Publikationen
2024
Leucine-rich glioma-inactivated 1 (LGI1) protein stimulates proliferation and IL-10 production in peripheral blood mononuclear cells of patients with LGI1 antibody-mediated autoimmune encephalitis in vitro
Goihl, Alexander; Reinhold, Dirk; Reinhold, Annegret; Schraven, Burkhart; Körtvélyessy, Péter
In: International journal of molecular sciences - Basel : Molecular Diversity Preservation International, Bd. 25 (2024), Heft 5, Artikel 2581, insges. 8 S.
Targeting caspase-8/c-FLIPL heterodimer in complex II promotes DL-mediated cell death
Hillert-Richter, Laura Katharina; König, Corinna; Ivanisenko, Nikita V.; Reinhold, Dirk; Lavrik, Inna N.
In: Frontiers in cell and developmental biology - Lausanne : Frontiers Media, Bd. 12 (2024), Artikel 1471216, insges. 16 S.
Why a pinch of zinc in liver disease matters
Grüngreiff, Kurt; Reinhold, Dirk; Maret, Wolfgang
In: Annals of hepatology - México : Assoc., Bd. 29 (2024), Heft 1, Artikel 101152, insges. 2 S.
Proteomic and transcriptomic profiling of brainstem, cerebellum and olfactory tissues in early- and late-phase COVID-19
Radke, Josefine; Meinhardt, Jenny; Aschman, Tom; Chua, Robert Lorenz; Farztdinov, Vadim; Lukassen, Sören; Ten, Foo Wei; Friebel, Ekaterina; Ishaque, Naveed; Franz, Jonas; Huhle, Valerie Helena; Mothes, Ronja; Peters, Kristin; Thomas, Carolina; Schneeberger, Shirin; Schumann, Elisa; Kawelke, Leona; Jünger, Julia; Horst, Viktor; Streit, Simon; Manitius, Regina; Körtvélyessy, Péter; Vielhaber, Stefan; Reinhold, Dirk; Hauser, Anja Erika; Osterloh, Anja; Enghard, Philipp; Ihlow, Jana; Elezkurtaj, Sefer; Horst, David; Kurth, Florian Michael; Müller, Marcel Alexander; Gassen, Nils C.; Melchert, Julia; Jechow, Katharina; Timmermann, Bernd; Fernandez-Zapata, Camila; Böttcher, Chotima; Stenzel, Werner; Krüger, Elke Helene; Landthaler, Markus; Wyler, Emanuel; Corman, Victor Max; Stadelmann, Christine; Ralser, Markus; Eils, Roland; Heppner, Frank L.; Mülleder, Michael; Conrad, Christian; Radbruch, Helena
In: Nature neuroscience - New York, NY : Nature America, Bd. 27 (2024), Heft 3, S. 409-420, insges. 32 S.
Targeting type I DED interactions at the DED filament serves as a sensitive switch for cell fate decisions
König, Corinna; Ivanisenko, Nikita V.; Hillert-Richter, Laura Katharina; Namjoshi, Deepti; Natu, Kalyani; Espe, Johannes; Reinhold, Dirk; Kolchanov, Nikolai A.; Ivanisenko, Vladimir A.; Kähne, Thilo; Bose, Kakoli; Lavrik, Inna N.
In: Cell chemical biology - Amsterdam : Elsevier, Bd. 31 (2024), Heft 11, S. 1969-1985, insges. 24 S.
2023
Patterns of allergic sensitization in adults with severe asthma - the ATLAS non-interventional study
Lücke, Eva Kristin; Schraven, Burkhart; Borucki, Katrin; Lux, Anke; Reinhold, Dirk; Wu, Qingyu; Schreiber, Jens
In: Journal of asthma - Philadelphia, Pa. : Taylor & Francis, Bd. 60 (2023), Heft 11, S. 2021-2029
Human glycoprotein-2 expressed in Brunner glands - a putative autoimmune target and link between Crohn's and coeliac disease
Roggenbuck, Dirk; Goihl, Alexander; Sowa, Mandy; Lopens, Steffi; Rödiger, Stefan; Schierack, Peter; Conrad, Karsten; Sommer, Ulrich; Jöhrens, Korinna; Grützmann, Robert; Reinhold, Dirk; Laaß, Martin Walter
In: Clinical immunology - San Diego, Calif. : Elsevier, Bd. 247 (2023), Artikel 109214, insges. 12 S.
Antibody properties associate with clinical phenotype in LGI1 encephalitis
Ludewig, Susann; Salzburger, Leonie; Goihl, Alexander; Rohne, Jana; Leypoldt, Frank; Bittner, Daniel Markus; Düzel, Emrah; Schraven, Burkhart; Reinhold, Dirk; Korte, Martin; Körtvélyessy, Péter
In: Cells - Basel : MDPI, Bd. 12 (2023), Heft 2, Artikel 282, insges. 15 S.
The brain reacting to COVID-19 - analysis of the cerebrospinal fluid proteome, RNA and inflammation
Reinhold, Dirk; Farztdinov, Vadim; Yan, Yan; Meisel, Christian; Sadlowski, Henrik; Kühn, Joachim; Perschel, Frank H.; Endres, Matthias; Düzel, Emrah; Vielhaber, Stefan; Guttek, Karina; Goihl, Alexander; Venø, Morten; Teegen, Bianca; Stöcker, Winfried; Stubbemann, Paula; Kurth, Florian Michael; Sander, Leif Erik; Ralser, Markus; Otto, Carolin; Streit, Simon; Jarius, Sven; Ruprecht, Klemens; Radbruch, Helena; Kjems, Jørgen; Mülleder, Michael; Heppner, Frank L.; Körtvélyessy, Péter
In: Journal of neuroinflammation - London : BioMed Central, Bd. 20 (2023), Artikel 30, insges. 16 S.
Allgemeine Kenntnisse zu häufig angewandten Testverfahren in der rheumatologisch-immunologischen Diagnostik und Forschung - General knowledge of frequently applied test procedures in rheumatological and immunological diagnostics and research
Reinhold, Dirk; Reinhold, Annegret; Schraven, Burkhart; Feist, Eugen
In: Zeitschrift für Rheumatologie - Darmstadt : Steinkopff, Bd. 82 (2023), Heft 4, S. 278-284
Plasma concentrations of anti-inflammatory cytokine TGF-β are associated with hippocampal structure related to explicit memory performance in older adults
Raschick, Matthias; Richter, Anni; Fischer, Larissa; Knopf, Lea; Schult, Annika; Yakupov, Renat; Behnisch, Gusalija; Guttek, Karina; Düzel, Emrah; Dunay, Ildikò Rita; Seidenbecher, Constanze; Schraven, Burkhart; Reinhold, Dirk; Schott, Björn H.
In: Journal of neural transmission - Wien [u.a.] : Springer, Bd. 130 (2023), Heft 8, S. 989-1002
Zinc aspartate induces proliferation of resting and antigen-stimulated human PBMC under high-density cell culture condition
Guttek, Karina; Reinhold, Annegret; Grüngreiff, Kurt; Schraven, Burkhart; Reinhold, Dirk
In: Journal of trace elements in medicine and biology - München : Elsevier, Bd. 77 (2023), Artikel 127152
2022
IgE-mediated sensitization towards frequent and rare allergens in severe asthmatics - the ATLAS project
Schreiber, Jens; Thurm, Christoph; Reinhold, Dirk; Luecke, Eva; Schraven, Burkhart; Wu, Qingyu; Lux, Anke; Mailänder, Claudia
In: American journal of respiratory and critical care medicine - New York, NY : American Thoracic Society, Bd. 205 (2022), Artikel A5703, insges. 1 S.
Unique lasting effects on immune composition and autoantibody prevalence after mild SARS-CoV-2 infections
Lingel, Holger; Meltendorf, Stefan; Billing, Ulrike; Thurm, Christoph; Vogel, Katrin; Majer, Christiane; Prätsch, Florian; Roggenbuck, Dirk; Heuft, Hans-Gert; Hachenberg, Thomas; Feist, Eugen; Reinhold, Dirk; Brunner-Weinzierl, Monika
In: European journal of immunology - Weinheim : Wiley-VCH, Bd. 52 (2022), Heft Suppl. 1, S. 173-174, Artikel P 028
Robust induction of neutralizing antibodies against the SARS-CoV-2 Delta variant after homologous Spikevax or heterologous Vaxzevria-Spikevax vaccination
Hammerschmidt, Swantje Iris Anna-Dorothea; Thurm, Christoph; Bos̆njak, Berislav; Bernhardt, Günter; Reinhold, Annegret; Willenzon, Stefanie; Ritter, Christiane; Reinhold, Dirk; Schraven, Burkhart; Förster, Reinhold
In: European journal of immunology - Weinheim : Wiley-VCH, Bd. 52 (2022), Heft 2, S. 356-359
Ionic mitigation of CD4 + T cell metabolic fitness, Th1 central nervous system autoimmunity and Th2 asthmatic airway inflammation by therapeutic zinc
Krone, Anna; Fu, Yanpeng; Schreiber, Simon; Kotrba, Johanna; Borde, Loisa; Nötzold, Aileen; Thurm, Christoph; Negele, Jonas; Franz, Tobias; Stegemann-Koniszewski, Sabine; Schreiber, Jens; Garbers, Christoph; Shukla, Aniruddh; Geffers, Robert; Schraven, Burkhart; Reinhold, Dirk; Dudeck, Anne; Reinhold, Annegret; Müller, Andreas Johann; Kahlfuß, Sascha
In: Scientific reports - [London] : Macmillan Publishers Limited, part of Springer Nature, Bd. 12 (2022), Artikel 1943, insges. 14 S.
IL-13 determines specific IgE responses and SARS-CoV-2 immunity after mild COVID-19 and novel mRNA vaccination
Meltendorf, Stefan; Vogel, Katrin; Thurm, Christoph; Prätsch, Florian; Reinhold, Annegret; Färber, Jacqueline; Heuft, Hans-Gert; Kaasch, Achim; Hachenberg, Thomas; Weinzierl, Stefan; Schraven, Burkhart; Reinhold, Dirk; Brunner-Weinzierl, Monika; Lingel, Holger
In: European journal of immunology - Weinheim : Wiley-VCH, Bd. 52 (2022), Heft 12, S. 1972-1979
Homologous and heterologous anti-COVID-19 vaccination does not induce new-onset formation of autoantibodies typically accompanying lupus erythematodes, rheumatoid arthritis, celiac disease and antiphospholipid syndrome
Thurm, Christoph; Reinhold, Annegret; Borucki, Katrin; Kahlfuß, Sascha; Feist, Eugen; Schreiber, Jens; Reinhold, Dirk; Schraven, Burkhart
In: Vaccines - Basel: MDPI, 2013, Bd. 10 (2022), 2, insges. 16 S.
Untersuchungen zur Wirkung von Adefovir-Dipivoxil und Pitavastatin auf die Funktion humaner T-Zellen
Voss, Linda; Reinhold, Dirk
In: Magdeburg: Universitätsbibliothek, Dissertation Otto-von-Guericke-Universität Magdeburg, Fakultät für Naturwissenschaften 2022, 1 Online-Ressource (IX, 103 Seiten, 4,65 MB) [Literaturverzeichnis: Seite 88-102][Literaturverzeichnis: Seite 88-102]
2021
The differential roles of zinc in immune responses and their potential implications in antiviral immunity against SARS-CoV-2
Reinhold, Dirk; Brocke, Stefan
In: Clinical nutrition - Amsterdam [u.a.]: Elsevier, Bd. 40 (2021), 2, S. 652
Screening of FDA-approved drug library identifies adefovir dipivoxil as highly potent inhibitor of T cell proliferation
Voss, Linda; Guttek, Karina; Reddig, Annika; Reinhold, Annegret; Voss, Martin; Schraven, Burkhart; Reinhold, Dirk
In: Frontiers in immunology - Lausanne: Frontiers Media, 2010, Bd. 11 (2021), insges. 16 S.
Albumin substitution in decompensated liver cirrhosis - don't forget zinc
Grüngreiff, Kurt; Gottstein, Thomas; Reinhold, Dirk; Blindauer, Claudia A.
In: Nutrients - Basel: MDPI, 2009, Bd. 13 (2021), 11, insges. 19 S.
Zinc aspartate induces IL-16 secretion and apoptosis in human T cells
Reinhold, Dirk; Guttek, Karina; Reddig, Annika; Voss, Linda; Schubert, Claudia; Kahlfuß, Sascha; Grüngreiff, Kurt; Schraven, Burkhart; Reinhold, Annegret
In: Biomedicines - Basel : MDPI, Bd. 9 (2021), Heft 3, Artikel 246, insges. 11 S.
Olfactory transmucosal SARS-CoV-2 invasion as a port of central nervous system entry in individuals with COVID-19
Meinhardt, Jenny; Radke, Josefine; Dittmayer, Carsten; Franz, Jonas; Thomas, Carolina; Mothes, Ronja; Laue, Michael; Schneider, Julia; Brünink, Sebastian; Greuel, Selina; Lehmann, Malte; Hassan, Olga; Aschman, Tom; Schumann, Elisa; Chua, Robert Lorenz; Conrad, Christian; Eils, Roland; Stenzel, Werner; Windgassen, Marc; Rößler, Larissa; Goebel, Hans Hilmar; Gelderblom, Hans R.; Martin, Hubert; Nitsche, Andreas; Schulz-Schaeffer, Walter J.; Hakroush, Samy; Winkler, Martin S.; Tampe, Björn; Scheibe, Franziska; Körtvélyessy, Péter; Reinhold, Dirk; Siegmund, Britta; Kühl, Anja Andrea; Elezkurtaj, Sefer; Horst, David; Oesterhelweg, Lars; Tsokos, Michael; Ingold Heppner, Barbara; Stadelmann, Christine; Drosten, Christian; Corman, Victor Max; Radbruch, Helena; Heppner, Frank L.
In: Nature neuroscience - New York, NY : Nature America, Bd. 24 (2021), Heft 2, S. 168-175, insges. 8 S. [Published: 30 November 2020]
Anti-glycoprotein 2 (anti-GP2) IgA and anti-neutrophil cytoplasmic antibodies to serine proteinase 3 (PR3-ANCA) - antibodies to predict severe disease, poor survival and cholangiocarcinoma in primary sclerosing cholangitis
Wunsch, Ewa; Norman, Gary L.; Milkiewicz, Małgorzata; Krawczyk, Marcin; Bentow, Chelsea; Shums, Zakera; Mahler, Michael; Lopens, Steffi; Reinhold, Dirk; Franke, Andre; Schramm, Christoph; Roggenbuck, Dirk; Milkiewicz, Piotr
In: Alimentary pharmacology & therapeutics - Oxford: Blackwell Science, 1987, Bd. 53 (2021), 2, S. 302-313
The activity and stability of p56Lck and TCR signaling do not depend on the co-chaperone Cdc37
Kowallik, Sarah; Kritikos, Andreas; Kästle, Matthias; Thurm, Christoph; Schraven, Burkhart; Reinhold, Dirk; Simeoni, Luca
In: International journal of molecular sciences - Basel : Molecular Diversity Preservation International, Bd. 22 (2021), Heft 1, Artikel 126, insges. 12 S.
Pitavastatin is a highly potent inhibitor of T-cell proliferation
Voss, Linda; Guttek, Karina; Reddig, Annika; Reinhold, Annegret; Voss, Martin; Simeoni, Luca; Schraven, Burkhart; Reinhold, Dirk
In: Pharmaceuticals - Basel : MDPI, Bd. 14 (2021), Heft 8, Artikel 727, insges. 19 S.
Unique autoantibody prevalence in long-term recovered SARS-CoV-2-infected individuals
Lingel, Holger; Meltendorf, Stefan; Billing, Ulrike; Thurm, Christoph; Vogel, Katrin; Majer, Christiane; Prätsch, Florian; Roggenbuck, Dirk; Heuft, Hans-Gert; Hachenberg, Thomas; Feist, Eugen; Reinhold, Dirk; Brunner-Weinzierl, Monika
In: Journal of autoimmunity - London : Academic Press, Bd. 122 (2021), Artikel 102682, insges. 8 S.
Eosinophilic pulmonary vasculitis as a manifestation of the hyperinflammatory phase of COVID-19. Correspondence
Luecke, Eva; Jeron, Andreas; Kröger, Andrea; Bruder, Dunja; Stegemann-Koniszewski, Sabine; Jechorek, Dörthe; Borucki, Katrin; Reinhold, Dirk; Reinhold, Annegret; Föllner, Sebastian; Walles, Thorsten; Hachenberg, Thomas; Schreiber, Jens
In: The journal of allergy and clinical immunology - Amsterdam [u.a.]: Elsevier, Bd. 147 (2021), 1, S. 112-113
Impact of different JAK inhibitors and methotrexate on lymphocyte proliferation and DNA damage
Reddig, Annika; Voss, Linda; Guttek, Karina; Roggenbuck, Dirk; Feist, Eugen; Reinhold, Dirk
In: Journal of Clinical Medicine - Basel: MDPI, 2012, Bd. 10 (2021), 7, insges. 19 S.
2020
Gastric cancer in autoimmune gastritis - a case-control study from the German centers of the staR project on gastric cancer research
Weise, Friederike; Vieth, Michael; Reinhold, Dirk; Haybäck, Johannes; Goni, Elisabetta; Lippert, Hans; Ridwelski, Karsten; Lingohr, Philipp; Schildberg, Claus; Vassos, Nikolaos; Kruschewski, Martin; Krasniuk, Iurii; Grimminger, Peter; Waidmann, Oliver; Peitz, Ulrich; Veits, Lothar; Kreuser, Nicole; Lang, Hauke; Bruns, Christiane; Möhler, Markus; Lordick, Florian; Gockel, Ines; Schumacher, Johannes; Malfertheiner, Peter; Venerito, Marino
In: United european gastroenterology journal - Hoboken, NJ : Wiley, Bd. 8 (2020), Heft 2, S. 175-184, insges. 10 S.
Autoimmune peripheral neuropathies and contribution of antiganglioside/sulphatide autoantibody testing
Roggenbuck, Dirk; Delmont, Emilien; Reinhold, Dirk; Schierack, Peter; Conrad, Karsten; Boucraut, Joseph
In: Mediterranean journal of rheumatology - Athens: Greek Rheumatology Society, 2015, Bd. 31 (2020), 1, S. 10-18
Ratio and index of neurofilament light chain indicate its origin in GuillainBarré Syndrome
Körtvélyessy, Péter; Kuhle, Jens; Düzel, Emrah; Vielhaber, Stefan; Schmidt, Christian; Heinius, Annika; Leypoldt, Frank; Schraven, Burkhart; Reinhold, Dirk; Leppert, David; Goihl, Alexander
In: Annals of Clinical and Translational Neurology - Chichester [u.a.] : Wiley, Bd. 7 (2020), Heft 11, S. 2213-2220
Zinc deficiency - an independent risk factor in the pathogenesis of haemorrhagic stroke?
Grüngreiff, Kurt; Gottstein, Thomas; Reinhold, Dirk
In: Nutrients - Basel: MDPI, 2009, Vol. 12.2020, 11, Art.-Nr. 3548, insgesamt 11 Seiten
Serum and CSF cytokine levels mirror different neuroimmunological mechanisms in patients with LGI1 and Caspr2 encephalitis
Körtvélyessy, Péter; Goihl, Alexander; Guttek, Karina; Schraven, Burkhart; Prüß, Harald; Reinhold, Dirk
In: Cytokine - Oxford [u.a.] : Elsevier - Vol. 135.2020, 155226
2019
Characterization of mice with a platelet-specific deletion of the adapter molecule ADAP
Rudolph, Jochen M.; Guttek, Karina; Weitz, Gabriele; Meinke, Clara Antonia; Kliche, Stefanie; Reinhold, Dirk; Schraven, Burkhart; Reinhold, Annegret
In: Molecular and cellular biology - Washington, DC : Soc - Bd. 39.2019, 9, Art.-Nr. e00365-18, insges. 16 S.
Immune cell-type specific ablation of adapter protein ADAP differentially modulates EAE
Rudolph, Jochen M.; Meinke, Clara; Voss, Martin; Guttek, Karina; Kliche, Stefanie; Reinhold, Dirk; Schraven, Burkhart; Reinhold, Annegret
In: Frontiers in immunology - Lausanne: Frontiers Media, 2010, Bd. 10.2019, Art.-Nr. 2343, insges. 13 S.
2018
Generation and validation of murine monoclonal and camelid recombinant single domain antibodies specific for human pancreatic glycoprotein 2
Schlör, Anja; Holzlöhner, Pamela; Listek, Martin; Grieß, Cindy; Butze, Monique; Micheel, Burkhard; Hentschel, Christian; Sowa, Mandy; Roggenbuck, Dirk; Schierack, Peter; Füner, Jonas; Schliebs, Erik; Goihl, Alexander; Reinhold, Dirk; Hanack, Katja
In: New biotechnology - New York, NY [u.a.]: Elsevier, Bd. 45 (2018), S. 60-68
Lower serum zinc levels in patients with multiple sclerosis compared to healthy controls
Pawlitzki, Marc; Uebelhör, Julia; Sweeney-Reed, Catherine M.; Stephanik, Heike; Hoffmann, Juliane; Lux, Anke; Reinhold, Dirk
In: Nutrients - Basel: MDPI, 2009, Bd. 10.2018, 8, Art.-Nr. 967, insges. 9 S.
Zinc aspartate suppresses proliferation and Th1/Th2/Th17 cytokine production of pre-activated human T cells in vitro
Guttek, Karina; Wagenbrett, Linda; Reinhold, Annegret; Grüngreiff, Kurt; Reinhold, Dirk
In: Journal of trace elements in medicine and biology - München: Elsevier, Bd. 49.2018, S. 86-90
Phosphorylated histone 2AX foci determination in capillary blood mononuclear cells
Sowa, Mandy; Reddig, Annika; Schierack, Peter; Reinhold, Dirk; Roggenbuck, Dirk
In: Journal of laboratory and precision medicine: an open access journal for high-quality research in laboratory medicine : JLPM - Hong Kong: AME Publishing Company, 2016, Bd. 3.2018, Art.-Nr. 45, insges. 6 S.
Antibodies against glycoprotein 2 display diagnostic advantages over ASCA in distinguishing CD from intestinal tuberculosis and intestinal Behçet's disease
Zhang, Shulan; Luo, Jing; Wu, Ziyan; Roggenbuck, Dirk; Schierack, Peter; Reinhold, Dirk; Li, Ji; Zeng, Xiaofeng; Zhang, Fengchun; Qian, Jiaming; Li, Yongzhe
In: Clinical and translational gastroenterology - London: Nature Publ. Group, Bd. 9.2018, Art.-Nr. e133, insges. 11 S.
The potential toxic impact of different gadolinium-based contrast agents combined with 7-T MRI on isolated human lymphocytes
Friebe, Björn; Godenschweger, Frank; Fatahi, Mahsa; Speck, Oliver; Roggenbuck, Dirk; Reinhold, Dirk; Reddig, Annika
In: European radiology experimental - [Cham]: Springer International Publishing, 2017, Bd. 2.2018, Art.-Nr. 40, insges. 9 S.
MRI and genetic damage - an update
Fatahi, Mahsa; Reddig, Annika; Friebe, Björn; Reinhold, Dirk; Speck, Oliver
In: Current radiology reports - New York, NY: Springer, 2013, Bd. 5.2017, Art.-Nr. 20, insges. 7 S.
CSF macrophage migration inhibitory factor levels did not predict steroid treatment response after optic neuritis in patients with multiple sclerosis
Pawlitzki, Marc; Sweeney-Reed, Catherine M.; Meuth, Sven; Reinhold, Dirk; Neumann, Jens
In: PLOS ONE - San Francisco, California, US: PLOS, 2006, Bd. 13.2018, 11, Art.-Nr. e0207726, insges. 11 S.
DNA damage assessment and potential applications in laboratory diagnostics and precision medicine
Reddig, Annika; Rübe, Claudia Elisabeth; Rödiger, Stefan; Schierack, Peter; Reinhold, Dirk; Roggenbuck, Dirk
In: Journal of laboratory and precision medicine - Hong Kong: AME Publishing Company, Bd. 3.2018, Art.-Nr. 31, insges. 15 S.
Comparison of different immunoassays for γH2AX quantification
Reddig, Annika; Roggenbuck, Dirk; Reinhold, Dirk
In: Journal of laboratory and precision medicine: an open access journal for high-quality research in laboratory medicine : JLPM - Hong Kong: AME Publishing Company, Bd. 3.2018, Art.-Nr. 80, insges. 9 S.
Combined treatment with zinc aspartate and intravenous immunoglobulins (IVIGs) ameliorates experimental autoimmune encephalomyelitis (EAE)
Straubel, Diana; Thielitz, Anja; Reinhold, Annegret; Grüngreiff, Kurt; Reinhold, Dirk
In: Journal of Immunology Research - New York, NY: Hindawi, 2018, Art.-ID 5982169, insges. 7 S.
Biomarkers of neurodegeneration in autoimmune-mediated encephalitis
Körtvélyessy, Péter; Prüß, Harald; Thurner, Lorenz; Maetzler, Walter; Vittore-Welliong, Deborah; Schultze-Amberger, Jörg; Heinze, Hans-Jochen; Reinhold, Dirk; Leypoldt, Frank; Schreiber, Stephan; Bittner, Daniel Markus
In: Frontiers in neurology - Lausanne : Frontiers Research Foundation - Bd. 9.2018, Art.-Nr. 668, insges. 10 S.
Expression of Zinc transporters ZIP4, ZIP14 and ZnT9 in hepatic carcinogenesis - an immunohistochemical study
Gartmann, Laura; Wex, Thomas; Grüngreiff, Kurt; Reinhold, Dirk; Kalinski, Thomas; Malfertheiner, Peter; Schütte, Kerstin
In: Journal of trace elements in medicine and biology - München: Elsevier, Bd. 49.2018, S. 35-42
Faktoren einer radiologischen Progression der chronisch progredient verlaufenden rheumatoiden Arthritis
Thunert, Isabell; Reinhold, Dirk; Oelzner, Peter
In: Magdeburg: Otto-von-Guericke-Universität Magdeburg, 2018, 72 Blätter, Diagramme
2017
Magenkarzinom auf dem Boden einer Autoimmungastritis - eine Fall-Kontroll-Studie aus dem staR (gastric cancer research)-Konsortium
Venerito, Marino; Weise, Friederike; Reinhold, Dirk; Ridwelski, Karsten; Goni, Elisabetta; Lingohr, Philipp; Matthaei, Hanno; Schildberg, Claus; Kruschewski, Martin; Krasniuk, Iurii; Grimminger, Peter; Möhler, Markus; Lippert, Hans; Wolff, Stefanie; Vieth, Michael; Veits, Lothar; Bruns, Christiane; Lordick, Florian; Gockel, Ines; Malfertheiner, Peter; Schumacher, Johannes
In: Zeitschrift für Gastroenterologie: offizielles Organ: Deutsche Gesellschaft für Verdauungs- und Stoffwechselkrankheiten mit Sektion Gastroenterologische Endoskopie : Österreichische Gesellschaft für Gastroenterologie und Hepatologie : Ungarische Gesellschaft für Gastroenterologie und Hepatologie - Stuttgart [u.a.]: Thieme, Bd. 55.2017, 8, insges. 1 S.
Insights into the mechanism of action of isotretinoin in human sebocytes in vitro
Mirdamadi, Yasaman Sadat; Thielitz, Anja; Wiede, Antje; Goihl, Alexander; Zouboulis, Christos C.; Reinhold, Dirk; Bommhardt, Ursula; Quist, Sven Roy; Gollnick, Harald
In: Experimental dermatology : the official journal of the European Immunodermatology Society - Oxford : Wiley-Blackwell, Bd. 26.2017, 3, P082, S. E35-E36
Insights into the mechanism of action of insulin-like growth factor-1 and insulin in human T cells in vitro
Mirdamadi, Yasaman Sadat; Thielitz, Anja; Goihl, Alexander; Guttek, Karina; Zouboulis, Christos C.; Reinhold, Dirk; Bommhardt, Ursula; Quist, Sven Roy; Gollnick, Harald
In: Experimental dermatology : the official journal of the European Immunodermatology Society - Oxford : Wiley-Blackwell, Bd. 26.2017, 3, P081 (OP06/06), S. E35
Clinical symptom tool raises index of suspicion for eosinophilic oesophagitis in adults and drives earlier biopsy for definitive diagnosis
Arnim, Ulrike; Roehl, Friedrich W.; Miehlke, Stephan; Jechorek, Dörthe; Reinhold, Dirk; Wex, Thomas; Malfertheiner, Peter
In: Gastroenterology - New York, NY : Elsevier - Bd. 152.2017, 5, Suppl. 1, Abs. Tu1094, S. S-859
Autoantibodies against glycoprotein 2 isoforms in pediatric patients with inflammatory bowel disease
Röber, Nadja; Noß, Lydia; Goihl, Alexander; Reinhold, Dirk; Jahn, Josefine; Laffolie, Jan; Johannes, Wolf; Flemming, Gunter Matthias Christian; Roggenbuck, Dirk; Conrad, Karsten; Laaß, Martin Walter
In: Inflammatory bowel diseases - Oxford : Oxford University Press, Bd. 23 (2017), 9, S. 1624-1636
Activated protein C protects from GvHD via PAR2/PAR3 signalling in regulatory T-cells
Ranjan, Satish; Goihl, Alexander; Kohli, Shrey; Gadi, Ihsan; Pierau, Mandy; Shahzad Hussain, Khurrum; Gupta, Dheerendra; Bock, Fabian; Wang, Hongjie; Shaikh, Haroon; Kähne, Thilo; Reinhold, Dirk; Bank, Ute; Zenclussen, Ana Claudia; Niemz, Jana; Schnöder, Tina; Brunner-Weinzierl, Monika; Fischer, Thomas; Kalinski, Thomas; Schraven, Burkhart; Luft, Thomas; Hühn, Jochen; Naumann, Michael; Heidel, Florian; Isermann, Berend
In: Nature Communications - [London] : Nature Publishing Group UK - 8(2017) Artikel-Nummer 311, 16 Seiten
Serological diagnosis and prognosis of severe acute pancreatitis by analysis of serum glycoprotein 2
Roggenbuck, Dirk; Goihl, Alexander; Hanack, Katja; Holzlöhner, Pamela; Hentschel, Christian; Veiczi, Miklós; Schierack, Peter; Reinhold, Dirk; Schulz, Hans-Ulrich
In: Clinical chemistry and laboratory medicine - Berlin [u.a.]: De Gruyter, 1998, Bd. 55 (2017), 6, S. 854-864
Der neuroimmunologische Boomerang nach Herpes-Simplex-Enzephalitis
Körtvélyessy, Péter; Bartels, Claudius; Galazky, Imke; Ranft, Karin; Sailer, Michael; Schreiber, Stephan; Heinsius, Valentin; Reinhold, Dirk; Vielhaber, Stefan; Heinze, Hans-Jochen; Huchtemann, Tessa
In: Klinische Neurophysiologie: Zeitschrift für Funktionsdiagnostik des Nervensystems ; EEG, EMG, MEP, Motorik, Elektronystagmographie, Kognitive Prozesse, Schlafstörungen - Stuttgart [u.a.]: Thieme, 1980, Bd. 48.2017, 1, S. 44-45
Clinical symptom tool that raises the index of suspicion for eosinophilic oesophagitis in adults and drives earlier biopsy for definitive diagnosis
Arnim, Ulrike; Röhl, Friedrich-Wilhelm; Miehlke, Stephan; Jechorek, Dörthe; Reinhold, Dirk; Wex, Thomas; Malfertheiner, Peter
In: Alimentary pharmacology & therapeutics - Oxford : Blackwell Science, Bd. 45 (2017), Heft 3, S. 417-426
Next-generation autoantibody testing by combination of screening and confirmation - the CytoBead® technology
Sowa, Mandy; Hiemann, Rico Frank; Schierack, Peter; Reinhold, Dirk; Conrad, Karsten; Roggenbuck, Dirk
In: Clinical reviews in allergy & immunology - [S.l.]: Springer US, 1983, Bd. 53 (2017), 1, S. 87-104
Impact of in vivo high-field-strength and ultra-high-field-strength MR imaging on DNA double-strand-break formation in human lymphocytes
Reddig, Annika; Fatahi, Mahsa; Roggenbuck, Dirk; Ricke, Jens; Reinhold, Dirk; Speck, Oliver; Friebe, Björn
In: Radiology - Oak Brook, Ill : Soc, Bd. 282 (2017), Heft 3, S. 782-789
Letter - multivariate clinical model for eosinophilic oesophagitis is this generalisable to a general population? : Authors reply
Arnim, Ulrike; Röhl, Friedrich-Wilhelm; Miehlke, Stephan; Jechorek, Dörthe; Reinhold, Dirk; Wex, Thomas; Malfertheiner, Peter
In: Alimentary pharmacology & therapeutics - Oxford : Blackwell Science, Bd. 45 (2017), Heft 6, S. 861
2016
In-vivo-Analyse von DNA-Doppelstrangbrüchen in humanen mononukleären Zellen (MNZ) nach klinischen MRT-Untersuchungen
Friebe, Björn; Fatahi, Mahsa; Reddig, Annika; Ricke, Jens; Reinhold, Dirk; Speck, Oliver
In: RöFo: Fortschritte auf dem Gebiet der Röntgenstrahlen und der bildgebenden Verfahren - Stuttgart [u.a.]: Thieme, Bd. 188.2016, S01, Abs. WISS307_1, insges. 1 S.
Camelid nanobodies specific to human pancreatic glycoprotein 2
Hanack, Katja; Schlör, Anja; Holzlöhner, Pamela; Listek, Martin; Bauer, Cindy; Butze, Monique; Micheel, Burkhard; Hentschel, Christian; Sowa, Mandy; Roggenbuck, Dirk; Schierack, Peter; Füner, Jonas; Schliebs, Erik; Goihl, Alexander; Reinhold, Dirk
In: The journal of immunology: official journal of the American Association of Immunologists - Rockville, Md.: American Association of Immunologists, 1916, Bd. 196.2016, 1 Suppl.,Abs. 209.8, insges. 1 S.
Characterisation of 242 patients with bullous pemphigoid with and without neurological disorder
Kolesnik, Malgorzata; Ambach, Andreas; Lux, Anke; Reinhold, Dirk; Bonnekoh, Bernd; Gollnick, Harald
In: Experimental dermatology - Oxford : Wiley-Blackwell - Bd. 25.2016, 3, P098, S. E17
Simultaneous detection of celiac disease-specific IgA antibodies and total IgA
Großmann, Kai; Röber, Nadja; Hiemann, Rico Frank; Rödiger, Stefan; Schierack, Peter; Reinhold, Dirk; Laass, Martin W.; Conrad, Karsten; Roggenbuck, Dirk
In: Autoimmunity highlights - Mailand: Springer Milan, 2010, Bd. 7.2016, 1, Art.-Nr. 2, insges. 10 S.
Immunomodulation by memantine in therapy of Alzheimer's disease is mediated through inhibition of Kv1.3 channels and T cell responsiveness
Lowinus, Theresa; Bose, Tanima; Busse, Stefan Gregor; Busse, Mandy; Reinhold, Dirk; Schraven, Burkhart; Bommhardt, Ursula H. H.
In: OncoTarget - [S.l.]: Impact Journals LLC, 2010, Bd. 7 (2016), 33, S. 53797-53807
Increased cerebral Tff1 expression in two murine models of neuroinflammation
Znalesniak, Eva B.; Fu, Ting; Guttek, Karina; Händel, Ulrike; Reinhold, Dirk; Hoffmann, Werner
In: Cellular physiology and biochemistry - Düsseldorf: Cell Physiol Biochem Press GmbH & Co KG, 1991, Bd. 39.2016, 6, S. 2287-2296
Autoimmunity in Crohn's disease - a putative stratification factor of the clinical phenotype
Roggenbuck, Dirk; Reinhold, Dirk; Baumgart, Daniel C.; Schierack, Peter; Conrad, Karsten; Laass, Martin W.
In: Advances in clinical chemistry - New York, NY [u.a.]: Elsevier, 2001, Bd. 77.2016, S. 77-101
DNA double-strand breaks and micronuclei in human blood lymphocytes after repeated whole body exposures to 7T Magnetic Resonance Imaging
Fatahi, Mahsa; Reddig, Annika; Vijayalaxmi,; Friebe, Björn; Hartig, Roland; Prihoda, Thomas J.; Ricke, Jens; Roggenbuck, Dirk; Reinhold, Dirk; Speck, Oliver
In: NeuroImage - Orlando, Fla: Academic Press, 1993, Bd. 133.2016, S. 288-293
Oxyntic gastric atrophy in Helicobacter pylori gastritis is distinct from autoimmune gastritis
Venerito, Marino; Varbanova, Mariya; Röhl, Friedrich-Wilhelm; Reinhold, Dirk; Frauenschläger, Katrin; Jechorek, Dörthe; Weigt, Jochen; Link, Alexander; Malfertheiner, Peter
In: Journal of clinical pathology - London : BMJ Publ. Group, Bd. 69 (2016), Heft 8, S. 677-685
The role of zinc in liver cirrhosis
Grüngreiff, Kurt; Reinhold, Dirk; Wedemeyer, Heiner
In: Annals of hepatology - México : Assoc., Bd. 15 (2016), Heft 1, S. 7-16
The mitochondrial phospholipid cardiolipin is involved in the regulation of T-cell proliferation
Mürke, Eik; Stoll, Steffan; Lendeckel, Uwe; Reinhold, Dirk; Schild, Lorenz
In: Biochimica et biophysica acta / Molecular and cell biology of lipids: BBA - Amsterdam: Elsevier, 1998, Bd. 1861.2016, 8 Pt. A, Seite 748-754
Serologic anti-GP2 antibodies are associated with genetic polymorphisms, fibrostenosis, and need for surgical resection in Crohn's disease
Degenhardt, Frauke; Dirmeier, Andrea; Lopez, Rocio; Lang, Sylvia; Kunst, Claudia; Roggenbuck, Dirk; Reinhold, Dirk; Szymczak, Silke; Rogler, Gerhard; Klebl, Frank; Franke, Andre; Rieder, Florian
In: Inflammatory bowel diseases - Oxford: Oxford University Press, 1995, Bd. 22.2016, 11, S. 2648-2657
Normal development and function of T cells in proline rich 7 (Prr7) deficient mice
Hrdinka, Matous; Sudan, Kritika; Just, Sissy; Drobek, Ales; Stepanek, Ondrej; Schlüter, Dirk; Reinhold, Dirk; Jordan, Bryen A.; Gintschel, Patricia; Schraven, Burkhart; Kreutz, Michael R.
In: PLOS ONE - San Francisco, California, US: PLOS, 2006, Bd. 11 (2016), 9, Art.-Nr. e0162863, insges. 15 S.
Cellular analyses in the monitoring of autoimmune diseases
Sack, Ulrich; Boldt, Andreas; Mallouk, Nora; Gruber, Rudolf; Krenn, Veit; Berger-Depincé, Anne-Emmanuelle; Conrad, Karsten; Tárnok, Attila; Lambert, Claude; Reinhold, Dirk; Fricke, Stephan
In: Autoimmunity reviews - Amsterdam [u.a.]: Elsevier Science, 2002, Bd. 15.2016, 9, S. 883-889
2015
Effects of isotretinoin on FoxO1 transcriptional regulation and molecular functions of SZ95 sebocytes
Mirdamadi, Yasaman Sadat; Thielitz, Anja; Wiede, Antje; Goihl, Alexander; Zouboulis, Christos C.; Reinhold, Dirk; Bommhardt, Ursula; Quist, Sven Roy; Gollnick, Harald
In: Experimental dermatology: the official journal of the European Immunodermatology Society - Oxford: Wiley-Blackwell, Bd. 24.2015, 3, P068, S. E12
Oxyntic gastric atrophy in autoimmune gastritis compared to Helicobacter pylori gastritis
Venerito, Marino; Varbanova, Mariya; Röhl, Friedrich-Wilhelm; Reinhold, Dirk; Frauenschläger, Katrin; Weigt, Jochen; Link, Alexander; Malfertheiner, Peter
In: Helicobacter - Oxford [u.a.] : Wiley-Blackwell - Bd. 20.2015, Suppl. 1, Abs. P01.17, S. 90
Serologische Diagnose der fortgeschrittenen oxyntischen Magenatrophie bei Patienten mit Helicobacter pylori Gastritis und Autoimmungastritis
Venerito, Marino; Varbanova, Mariya; Röhl, Friedrich-Wilhelm; Link, Alexander; Reinhold, Dirk; Frauenschläger, Katrin; Malfertheiner, Peter
In: Zeitschrift für Gastroenterologie : offizielles Organ: Deutsche Gesellschaft für Verdauungs- und Stoffwechselkrankheiten mit Sektion Gastroenterologische Endoskopie ; Österreichische Gesellschaft für Gastroenterologie und Hepatologie ; Ungarische Gesellschaft für Gastroenterologie und Hepatologie. - Stuttgart [u.a.] : Thieme; Bd. 53.2015, 8, KG019, insges. 1 S.
Assessment of modulated cytostatic drug resistance by automated [gamma]H2AX analysis
Reddig, Annika; Lorenz, Sebastian; Hiemann, Rico Frank; Guttek, Karina; Hartig, Roland; Heiserich, Lisa; Eberle, Caroline; Peters, Vanessa; Schierack, Peter; Sack, Ulrich; Roggenbuck, Dirk; Reinhold, Dirk
In: Cytometry / A - Hoboken, NJ: Wiley-Liss, 2003, Bd. 87.2015, 8, S. 724-732
Evidence of Crohn's disease-related anti-glycoprotein 2 antibodies in patients with celiac disease
Roggenbuck, Dirk; Vermeire, Severine; Hoffman, Ilse; Reinhold, Dirk; Schierack, Peter; Goihl, Alexander; Arnim, Ulrike; Hertogh, Gert; Polymeros, Dimitrios; Bogdanos, Dimitrios P.; Bossuyt, Xavier
In: Clinical chemistry and laboratory medicine - Berlin [u.a.] : De Gruyter, Bd. 53 (2015), Heft 9, S. 1349-1357
Autoreactivity to isoforms of glycoprotein 2 in inflammatory bowel disease. Letter to the editor
Roggenbuck, Dirk; Röber, Nadja; Bogdanos, Dimitrios P.; Goihl, Alexander; Reinhold, Dirk; Conrad, Karsten; Laaß, Martin Walter
In: Clinica chimica acta: international journal of clinical chemistry and applied molecular biology - Amsterdam [u.a.]: Elsevier Science, Bd. 442 (2015), S. 82-83
The adhesion- and degranulation-promoting adaptor protein and its role in the modulation of experimental autoimmune encephalomyelitis
Engelmann, Swen; Togni, Mauro; Kliche, Stefanie; Reinhold, Dirk; Schraven, Burkhart; Reinhold, Annegret
In: Critical reviews in immunology - Boca Raton, Fla. : CRC Press, Bd. 35 (2015), Heft 1, S. 1-14
Der Einfluss des Spurenelements Zink auf das Immunsystem
Schubert, Claudia; Guttek, Karina; Reinhold, Annegret; Grüngreiff, Kurt; Reinhold, Dirk
In: Laboratoriumsmedizin - Berlin [u.a.]: de Gruyter, 1977, Bd. 39.2015, 3, S. 135-144
Analysis of DNA double-strand breaks and cytotoxicity after 7 Tesla magnetic resonance imaging of isolated human lymphocytes
Reddig, Annika; Fatahi, Mahsa; Friebe, Björn; Guttek, Karina; Hartig, Roland; Godenschweger, Frank; Roggenbuck, Dirk; Ricke, Jens; Reinhold, Dirk; Speck, Oliver
In: PLOS ONE - San Francisco, California, US : PLOS - Vol. 10.2015, 7, Art. e0132702, insgesamt 14 S.
MiR-20a inhibits TCR-mediated signaling and cytokine production in human naïve CD4+ T cells
Reddycherla, Amarendra Varma; Meinert, Ines; Reinhold, Annegret; Reinhold, Dirk; Schraven, Burkhart; Simeoni, Luca
In: PLOS ONE - San Francisco, California, US: PLOS, Bd. 10.2015, 4, Art. e0125311, insges. 17 S.
Second generation analysis of antinuclear antibody (ANA) by combination of screening and confirmatory testing
Scholz, Juliane; Großmann, Kai; Knütter, Ilka; Hiemann, Rico Frank; Sowa, Mandy; Röber, Nadja; Rödiger, Stefan; Schierack, Peter; Reinhold, Dirk; Bogdanos, Dimitrios P.; Meroni, Pier Luigi; Radice, Antonella; Conrad, Karsten; Roggenbuck, Dirk
In: Clinical chemistry and laboratory medicine - Berlin [u.a.]: De Gruyter, Bd. 53 (2015), 12, S. 1991-2002
Insulin and insulin-like growth factor-1 can modulate the phosphoinositide-3-kinase/Akt/FoxO1 pathway in SZ95 sebocytes in vitro
Mirdamadi, Yasaman Sadat; Thielitz, Anja; Wiede, Antje; Goihl, Alexander; Papakonstantinou, Eleni; Hartig, Roland; Zouboulis, Christos C.; Reinhold, Dirk; Simeoni, Luca; Bommhardt, Ursula; Quist, Sven Roy; Gollnick, Harald
In: Molecular and cellular endocrinology - Amsterdam [u.a.]: Elsevier Science, Bd. 415 (2015), S. 32-44
Species-specific and pathotype-specific binding of bacteria to zymogen granule membrane glycoprotein 2 (GP2). Postscript
Schierack, Peter; Rödiger, Stefan; Kolenda, Rafal; Hiemann, Rico Frank; Berger, Enrico; Grzymajło, Krzysztof; Swidsinski, Alexander; Juretzek, Thomas; Meissner, Dirk; Mydlak, Karsten; Reinhold, Dirk; Nolan, Lisa K.; Roggenbuck, Dirk
In: Gut - London: BMJ Publishing Group, 1960, Bd. 64.2015, 3, S. 517-519
Autoimmune gastritis in autoimmune thyroid disease
Venerito, Marino; Radünz, Marcus; Reschke, Kirsten; Reinhold, Dirk; Frauenschläger, Katrin; Jechorek, Dörthe; DiMario, Francesco; Malfertheiner, Peter
In: Alimentary pharmacology & therapeutics - Oxford : Blackwell Science, Bd. 41 (2015), Heft 7, S. 686-693
Interleukin 18 als Diagnose- und Verlaufsparameter beim Morbus Still
Kudela, Holger; Reinhold, Dirk
In: Magdeburg, Univ., Med. Fak., Diss., 2015, 91 Bl
Regulation der Interleukin-2-Sekretion in primären humanen T-Lymphozyten durch Cannabinoide
Wachter, Doreen; Reinhold, Dirk
In: Magdeburg Univ., Med. Fak., Diss., 2015, VIII, 77 Bl, Ill., graph. Darst.
2014
Autoantibodies to glycoprotein 2 are associated with the clinical phenotype in Crohn's disease
Roggenbuck, Dirk; Bogdanos, Dimitrios P.; Reinhold, Dirk; Arnim, Ulrike; Malfertheiner, Peter; Forbes, Alastair; Conrad, Karsten; Laaß, Martin Walter
In: Zeitschrift für Gastroenterologie - Stuttgart [u.a.] : Thieme - Bd. 52.2014, Nr. 8, FV13, insges. 1 S.
Oral zinc aspartate treats experimental autoimmune encephalomyelitis
Schubert, Claudia; Guttek, Karina; Grüngreiff, Kurt; Thielitz, Anja; Bühling, Frank; Reinhold, Annegret; Brocke, Stefan; Reinhold, Dirk
In: BioMetals - Dordrecht [u.a.]: Springer Science + Business Media B.V, Bd. 27 (2014), 6, S. 1249-1262
Constitutive expression of murine c-FLIPR causes autoimmunity in aged mice
Ewald, Frida; Annemann, Michaela; Pils, Marina C.; Plaza-Sirvent, Carlos; Neff, Frauke; Erck, Christian; Reinhold, Dirk; Schmitz, Ingo
In: Cell death & disease - London [u.a.]: Nature Publishing Group, Bd. 5.2014, Art.-Nr. e1168, insges. 12 S.
Simultaneous automated screening and confirmatory testing for vasculitis-specific ANCA
Sowa, Mandy; Großmann, Kai; Knütter, Ilka; Hiemann, Rico Frank; Röber, Nadja; Anderer, Ursula; Csernok, Elena; Bogdanos, Dimitrios P.; Borghi, Maria Orietta; Meroni, Pier Luigi; Schierack, Peter; Reinhold, Dirk; Conrad, Karsten; Roggenbuck, Dirk
In: PLOS ONE - San Francisco, California, US: PLOS, Bd. 9.2014, 9, Art.-Nr. e107743, insges. 11 S.
DPP4-directed therapeutic strategies for MERS-CoV. Correspondence
Reinhold, Dirk; Brocke, Stefan
In: The lancet
Selective targeting of transforming growth factor-beta1 into TCR/CD28 signalling plasma membrane domains silences T cell activation
Harder, Thomas; Guttek, Karina; Philipsen, Lars; Simeoni, Luca; Schraven, Burkhart; Reinhold, Dirk
In: Cell communication and signaling - London: Biomed Central, 2003, Bd. 12.2014, Art.-Nr. 74, insges. 8 S.
Digital immunofluorescence enables automated detection of antinuclear antibody endpoint titers avoiding serial dilution
Roggenbuck, Dirk; Hiemann, Rico Frank; Schierack, Peter; Reinhold, Dirk; Conrad, Karsten
In: Clinical chemistry and laboratory medicine - Berlin [u.a.]: De Gruyter, Bd. 52.2014, 2, S. e9-e11
Treatment of severe autoimmune blistering skin diseases with combination of protein A immunoadsorption and rituximab - a protocol without initial high dose or pulse steroid medication
Kolesnik, Malgorzata; Becker, Elke; Reinhold, Dirk; Ambach, Andreas; Heim, Marcell U.; Gollnick, Harald; Bonnekoh, Bernd
In: Journal of the European Academy of Dermatology and Venereology - Oxford [u.a.]: Wiley-Blackwell, Bd. 28 (2014), 6, S. 771-780
Expression analysis of zinc transporters in resting and stimulated human peripheral blood mononuclear cells
Wex, Thomas; Grüngreiff, Kurt; Schütte, Kerstin; Stengritt, Maren; Reinhold, Dirk
In: Biomedical reports: an international journal devoted to biomedical research - Athens: Spandidos Publ., Bd. 2 (2014), 2, S. 217-222
Crohnʾs disease specific pancreatic antibodies - clinical and pathophysiological challenges
Roggenbuck, Dirk; Reinhold, Dirk; Schierack, Peter; Bogdanos, Dimitrios P.; Conrad, Karsten; Laaß, Martin Walter
In: Clinical chemistry and laboratory medicine - Berlin [u.a.]: De Gruyter, Bd. 52 (2014), 4, S. 483-494
2013
Aklides - a highly versatile imaging platform for detection of ANCA
Knütter, Ilka; Großmann, Kai; Hiemann, Rico Frank; Reinhold, Dirk; Csernok, Elena; Roggenbuck, Dirk
In: La presse médicale & Quarterly medical review - Issy-les-Moulineaux : Elsevier Masson, Bd. 42 (2013), Heft 4, S. 686
Training intervention improves memory in mild cognitive impairment and healthy controls, but plasma BDNF acts differentially
Bittner, Daniel Markus; Bittner, Verena; Hausmann, Janet; Reinhold, Dirk; Wesenberg, Judith; Westphal, Sabine; Heinze, Hans-Jochen; Schott, Björn H.; Kaufmann, Jörn; Müller, N. J.
In: Journal of psychophysiology - Göttingen : Hogrefe & Huber - Bd. 27.2013, Suppl. 1, S. 49
DP IV/CD26 effector peptides
Ansorge, Siegfried; Reinhold, Dirk
In: Handbook of biologically active peptides , 2. ed. - Amsterdam : Elsevier Academic Press ; Kastin, Abba J. . - 2013, S. 664-670
Humanes Leukozytenantigensystem in der Augenheilkunde
Lapp, Thabo; Reinhold, Dirk; Böhringer, Daniel; Reinhard, Thomas
In: Der Ophthalmologe - Berlin: Springer, Bd. 110 (2013), 9, S. 849-861
Cooperative immunoregulatory function of the transmembrane adaptor proteins SIT and LAX
Arndt, Börge; Kalinski, Thomas; Reinhold, Dirk; Thielitz, Anja; Roessner, Albert; Schraven, Burkhart; Simeoni, Luca
In: Journal of leukocyte biology - Bethesda, Md. : FASEB, Bd. 93 (2013), Heft 3, S. 353-362
T cell-independent modulation of experimental autoimmune encephalomyelitis in ADAP-deficient mice
Engelmann, Swen; Togni, Mauro; Reinhold, Dirk; Thielitz, Anja; Reichardt, Peter; Kliche, Stefanie; Schraven, Burkhart; Reinhold, Annegret
In: The journal of immunology - Bethesda, Md: Soc, Bd. 191 (2013), 10, S. 4950-4959
Fully automated analysis of chemically induced [gamma]H2AX foci in human peripheral blood mononuclear cells by indirect immunofluorescence
Willitzki, Annika; Lorenz, Sebastian; Hiemann, Rico Frank; Guttek, Karina; Goihl, Alexander; Hartig, Roland; Conrad, Karsten; Feist, Eugen; Sack, Ulrich; Schierack, Peter; Heiserich, Lisa; Eberle, Caroline; Peters, Vanessa; Roggenbuck, Dirk; Reinhold, Dirk
In: Cytometry / A - Hoboken, NJ: Wiley-Liss, Bd. 83 (2013), 11, S. 1017-1026
Glycoprotein 2 antibodies in Crohn's disease
Roggenbuck, Dirk; Reinhold, Dirk; Werner, Lael; Schierack, Peter; Bogdanos, Dimitrios P.; Conrad, Karsten
In: Advances in clinical chemistry - New York, NY [u.a.]: Elsevier, Bd. 60 (2013), S. 187-208
Glycoprotein 2 antibodies in inflammatory bowel disease - No association with disease phenotype?. Letters to the editor
Roggenbuck, Dirk; Humbel, René-Louis; Reinhold, Dirk; Bogdanos, Dimitrios P.; Conrad, Karsten; Laaß, Martin Walter
In: Journal of pediatric gastroenterology and nutrition - Philadelphia, Pa.: Lippincott Williams & Wilkins, Bd. 56 (2013), 1, S. e5
Standardization of automated interpretation of immunofluorescence tests. Letter to the editor
Roggenbuck, Dirk; Hiemann, Rico Frank; Bogdanos, Dimitrios; Reinhold, Dirk; Conrad, Karsten
In: Clinica chimica acta: CCA ; international journal of clinical chemistry and medical biochemistry / ed. in chief S. C. Frazer - Amsterdam: Elsevier, Bd. 421 (2013), S. 168-169
Stimulated human peripheral T cells produce high amounts of IL-35 protein in a proliferation-dependent manner
Guttek, Karina; Reinhold, Dirk
In: Cytokine - Oxford [u.a.]: Elsevier, Bd. 64 (2013), 1, S. 46-50
2012
Pancreatic-specific autoantibodies to glycoprotein 2 mirror disease location and behaviour in younger patients with Crohn's disease
Bogdanos, Dimitrios P.; Roggenbuck, Dirk; Reinhold, Dirk; Wex, Thomas; Pavlidis, Polychronis; Arnim, Ulrike; Malfertheiner, Peter; Forbes, Alastair; Conrad, Karsten; Laaß, Martin Walter
In: BMC gastroenterology - London : BioMed Central - Bd. 12.2012, Art.-Nr. 102, insges. 9 S.
Dipeptidyl peptidase IV, aminopeptidase N and DPIV/APN-like proteases in cerebral ischemia
Röhnert, Peter; Schmidt, Werner; Emmerlich, Patrick; Goihl, Alexander; Wrenger, Sabine; Bank, Ute; Nordhoff, Karsten; Täger, Michael; Ansorge, Siegfried; Reinhold, Dirk; Striggow, Frank
In: Journal of neuroinflammation - London : BioMed Central - Bd. 9.2012, Artikel-Nr.44, insges. 15 S.
Autoantibody diagnostics in clinical practice
Conrad, Karsten; Roggenbuck, Dirk; Reinhold, Dirk; Sack, Ulrich
In: Autoimmunity reviews - Amsterdam [u.a.] : Elsevier, Bd. 11 (2012), Heft 3, S. 207-211
Zinc aspartate suppresses T cell activation in vitro and relapsing experimental autoimmune encephalomyelitis in SJL/J mice
Stoye, Diana; Schubert, Claudia; Goihl, Alexander; Guttek, Karina; Reinhold, Annegret; Brocke, Stefan; Grüngreiff, Kurt; Reinhold, Dirk
In: BioMetals - Oxford : Rapid Communications, Bd. 25 (2012), Heft 3, S. 529-539
Progressive lipo-lymphedema associated with increased activity of dermal fibroblasts in monoclonal gammopathy of undetermined significance: is there a causal relationship?
Thielitz, Anja; Bellutti, Michael; Bonnekoh, Bernd; Franke, Ingolf; Wiede, Antje; Lotzing, Marita; Reinhold, Dirk; Gollnick, Harald
In: Lymphology: official organ of the International Society of Lymphology / chief ed. J. Bircher - Tucson, Ariz.: International Society of Lymphology: official organ of the International Society of Lymphology / chief ed. J. Bircher, Bd. 45 (2012), 3, S. 124-129
New platform technology for comprehensive serological diagnostics of autoimmune diseases
Willitzki, Annika; Hiemann, Rico Frank; Peters, Vanessa; Sack, Ulrich; Schierack, Peter; Rödiger, Stefan; Anderer, Ursula; Conrad, Karsten; Bogdanos, Dimitrios P.; Reinhold, Dirk; Roggenbuck, Dirk
In: Clinical & developmental immunology - New York, NY: Hindawi, 2012, Art.ID 284740, insges. 18 S.
The Authors' reply. Letter
Roggenbuck, Dirk; Reinhold, Dirk; Wex, Thomas; Arnim, Ulrike; Malfertheiner, Peter; Sturm, Andreas; Werner, Lael; Bogdanos, Dimitrios P.; Laaß, Martin Walter; Conrad, Karsten
In: Gut - London : BMJ Publishing Group, Bd. 61 (2012), Heft 1, S. 164-165
Asialoglycoprotein receptor (ASGPR): a peculiar target of liver-specific autoimmunity
Roggenbuck, Dirk; Mytilinaiou, Maria G.; Lapin, Sergey V.; Reinhold, Dirk; Conrad, Karsten
In: Autoimmunity highlights - Mailand: Springer Milan, Bd. 3 (2012), 3, S. 119-125
Methodologic issues in the measurement of interleukin-16 in clinical blood samples using immunoassays
Goihl, Alexander; Rolle, Anna-Maria; Kähne, Thilo; Reinhold, Annegret; Wrenger, Sabine; Reinhold, Dirk
In: Cytokine - Oxford [u.a.] : Elsevier, Bd. 58 (2012), Heft 1, S. 1-5
Automated interpretation of ANCA patterns - a new approach in the serology of ANCA-associated vasculitis
Knütter, Ilka; Hiemann, Rico Frank; Brumma, Therese; Büttner, Thomas; Großmann, Kai; Cusini, Marco; Pregnolato, Francesca; Borghi, Maria Orietta; Anderer, Ursula; Conrad, Karsten; Reinhold, Dirk; Roggenbuck, Dirk; Csernok, Elena
In: Arthritis Research & Therapy - London: BioMed Central, Bd. 14.2012, 6, Art.-Nr. R271, insges. 10 S.
Pro-inflammatory effector Th cells transmigrate through anti-inflammatory environments into the murine fetus
Wienecke, Janine; Hebel, Katrin; Hegel, Kolja J.; Pierau, Mandy; Brune, Thomas; Reinhold, Dirk; Pethe, Annette; Brunner-Weinzierl, Monika
In: Placenta - Amsterdam [u.a.] : Elsevier, Bd. 33 (2012), Heft 1, S. 39-46
The adapter protein ADAP is required for selected dendritic cell functions
Togni, Mauro; Engelmann, Swen; Reinhold, Dirk; Schraven, Burkhart; Reinhold, Annegret
In: Cell communication and signaling - London : Biomed Central - Bd. 10.2012, Art. 14, insges. 10 S.
Ektopeptidasen - Von der Forschung in die Klinik - Ectopeptidases - from research to clinical application
Thielitz, Anja; Reinhold, Dirk; Täger, Michael; Bank, Ute; Ansorge, Siegfried; Gollnick, Harald
In: Aktuelle Dermatologie - Stuttgart : Thieme, Bd. 38 (2012), Heft 3, S. 85-87
Altes Immunsystem - neue Erkenntnisse? - Bedeutung mononukleärer Zellen bei der allogenen Hornhauttransplantatabstoßung
Lapp, Thabo; Reinhold, Dirk; Maier, Philip; Reinhard, Thomas
In: Der Ophthalmologe - Berlin : Springer Medizin, Bd. 109 (2012), Heft 9, S. 869-878
2011
Outside or inside: role of the subcellular localization of DP4-like enzymes for substrate conversion and inhibitor effects
Bank, Ute; Heimburg, Anke; Wohlfarth, Astrid; Koch, Gudrun; Nordhoff, Karsten; Julius, Heiko; Helmuth, Martin; Breyer, Doreen; Reinhold, Dirk; Täger, Michael; Ansorge, Siegfried
In: Biological chemistry - Berlin [u.a.] : de Gruyter, Bd. 392 (2011), Heft 3, S. 169-187
The zymogen granule protein 2 (GP2) binds to scavenger receptor expressed on endothelial cells I (SREC-I)
Hölzl, Markus A.; Hofer, Johannes; Kovarik, Johannes J.; Roggenbuck, Dirk; Reinhold, Dirk; Goihl, Alexander; Gärtner, Miriam; Steinberger, Peter; Zlabinger, Gerhard J.
In: Cellular immunology - San Diego, Calif. : Elsevier, Bd. 267 (2011), Heft 2, S. 88-93
Autoantibodies to GP2, the major zymogen granule membrane glycoprotein, are new markers in Crohn's disease
Roggenbuck, Dirk; Reinhold, Dirk; Wex, Thomas; Goihl, Alexander; Arnim, Ulrike; Malfertheiner, Peter; Büttner, Thomas; Porstmann, Tomas; Porstmann, Silvia; Liedvogel, Bodo; Bogdanos, Dimitrios P.; Laaß, Martin Walter; Conrad, Karsten
In: Clinica chimica acta - Amsterdam : Elsevier, Bd. 412 (2011), Heft 9/10, S. 718-724
PETIR-001, a dual inhibitor of dipeptidyl peptidase IV (DP IV) and aminopeptidase N (APN), ameliorates experimental autoimmune encephalomyelitis in SJL/J mice
Reinhold, Dirk; Bank, Ute; Entz, Dominik; Goihl, Alexander; Stoye, Diana; Wrenger, Sabine; Brocke, Stefan; Thielitz, Anja; Stefin, Sofia; Nordhoff, Karsten; Heimburg, Anke; Täger, Michael; Ansorge, Siegfried
In: Biological chemistry - Berlin [u.a.] : de Gruyter, Bd. 392 (2011), Heft 3, S. 233-237
The transmembrane adaptor protein SIT inhibits TCR-mediated signaling
Arndt, Börge; Krieger, Tina; Kalinski, Thomas; Thielitz, Anja; Reinhold, Dirk; Roessner, Albert; Schraven, Burkhart; Simeoni, Luca
In: PLOS ONE - San Francisco, California, US : PLOS - Bd. 6.2011, 9, Art.-Nr. e23761 insges. 7 S.
Novel aspects of cellular action of dipeptidyl peptidase IV/CD26
Ansorge, Siegfried; Nordhoff, Karsten; Bank, Ute; Heimburg, Anke; Julius, Heiko; Breyer, Doreen; Thielitz, Anja; Reinhold, Dirk; Täger, Michael
In: Biological chemistry - Berlin [u.a.] : de Gruyter, Bd. 392 (2011), Heft 3, S. 153-168
Divergent actions by inhibitors of DP IV and APN family enzymes on CD4+ Teff cell motility and functions
Biton, Aliza; Ansorge, Siegfried; Bank, Ute; Täger, Michael; Reinhold, Dirk; Brocke, Stefan
In: Immunobiology - Amsterdam : Elsevier, Bd. 216 (2011), Heft 12, S. 1295-1301
Diagnostic value, clinical utility and pathogenic significance of reactivity to the molecular targets of Crohn's disease specific-pancreatic autoantibodies
Bogdanos, Dimitrios P.; Rigopoulou, Eirini I.; Smyk, Daniel S.; Roggenbuck, Dirk; Reinhold, Dirk; Forbes, Alastair; Laaß, Martin Walter; Conrad, Karsten
In: Autoimmunity reviews - Amsterdam [u.a.] : Elsevier, Bd. 11 (2011), Heft 2, S. 143-148
Standardized detection of anti-ds DNA antibodies by indirect immunofluorescence - a new age for confirmatory tests in SLE diagnostics. Letter to the editor
Roggenbuck, Dirk; Reinhold, Dirk; Hiemann, Rico Frank; Anderer, Ursula; Conrad, Karsten
In: Clinica chimica acta - Amsterdam : Elsevier, Bd. 412 (2011), Heft 21/22, S. 2011-2012
2010
Profiling of rheumatoid arthritis associated autoantibodies
Conrad, Karsten; Roggenbuck, Dirk; Reinhold, Dirk; Dörner, Thomas
In: Autoimmunity reviews - Amsterdam [u.a.] : Elsevier, Bd. 9 (2010), Heft 6, S. 431-435
High sensitive detection of double-stranded DNA antibodies by a modified Crithidia luciliae immunofluorescence test may improve diagnosis of systemic lupus erythematosus
Roggenbuck, Dirk; Conrad, Karsten; Reinhold, Dirk
In: Clinica chimica acta - Amsterdam : Elsevier, Bd. 411 (2010), Heft 21/22, S. 1837-1838
2009
Ektopeptidaseinhibitoren als Instrumente eines neuen Therapiekonzeptes zur Behandlung der Akne vulgaris
Thielitz, Anja; Reinhold, Dirk; Täger, Michael; Ansorge, Siegfried; Gollnick, Harald
In: Spitzenforschung in der Dermatologie und Allergologie: Innovationen und Auszeichnungen 2009 / DGAKI; DDG. [Red.-Leitung und Koordinierung der Beitr.: Angela Verse-Herrmann]: Innovationen und Auszeichnungen 2009 - Lampertheim: Alpha-Informationsges., 2009 . - 2009, insges. 6 S.
Expression of SKAP-HOM in DCs is required for an optimal immune response in vivo
Reinhold, Annegret; Reimann, Sibylle; Reinhold, Dirk; Schraven, Burkhart; Togni, Mauro
In: Journal of leukocyte biology - Bethesda, Md. : FASEB, Bd. 86 (2009), Heft 1, S. 61-71
Recent insights into the role of dipeptidyl aminopeptidase IV (DPIV) and aminopeptidase N (APN) families in immune functions
Ansorge, Siegfried; Bank, Ute; Heimburg, Anke; Helmuth, Martin; Koch, Gudrun; Tadje, Janine; Lendeckel, Uwe; Wolke, Carmen; Neubert, Klaus; Faust, Jürgen; Fuchs, Petra; Reinhold, Dirk; Thielitz, Anja; Täger, Michael
In: Clinical chemistry and laboratory medicine - Berlin : de Gruyter, Bd. 47 (2009), Heft 3, S. 253-261
High-sensitive detection of autoantibodies against proteinase-3 by a novel third-generation enzyme-linked immunosorbent assay
Roggenbuck, Dirk; Büttner, Thomas; Hoffmann, Lars; Schmechta, Helmuth; Reinhold, Dirk; Conrad, Karsten
In: Annals of the New York Academy of Sciences - Hoboken, NJ : Wiley Subscription Services, Bd. 1173 (2009), S. 41-46
Modulation of cytokine production and silica-induced lung fibrosis by inhibitors of aminopeptidase N and of dipeptidyl peptidase-IV-related proteases
Kühlmann, Ulrike C.; Chwieralski, Caroline Elisabeth; Brule, Sybille; Röcken, Christoph; Reinhold, Dirk; Welte, Tobias; Bühling, Frank
In: Life sciences - Amsterdam [u.a.] : Elsevier, Bd. 84 (2009), Heft 1/2, S. 1-11
Plasma concentrations of zinc, copper, interleukin-6 and interferon-[gamma], and plasma dipeptidyl peptidase IV activity in chronic hepatitis C
Grüngreiff, Kurt; Hebell, Thomas; Gutensohn, Kai; Reinhold, Annegret; Reinhold, Dirk
In: Molecular medicine reports . - Athens : Spandidos Publ., Bd. 2.2009, 1, S. 63-68; Abstract
Radiation-induced matrix production of lung fibroblasts is regulated by interleukin-8
Kühlmann, Ulrike C.; Chwieralski, Caroline Elisabeth; Reinhold, Dirk; Welte, Tobias; Bühling, Frank
In: International journal of radiation biology - Abingdon : Informa Healthcare, Bd. 85 (2009), Heft 2, S. 138-143
High sensitive detection of double-stranded DNA autoantibodies by a modified Crithidia luciliae immunofluorescence test
Conrad, Karsten; Ittenson, Annelore; Reinhold, Dirk; Fischer, Richard; Roggenbuck, Dirk; Büttner, Thomas; Bosselmann, Hans-Peter; Steinbach, Jörg; Schößler, Werner
In: Annals of the New York Academy of Sciences - Hoboken, NJ : Wiley Subscription Services, Bd. 1173 (2009), S. 180-185
Identification of GP2, the major zymogen granule membrane glycoprotein, as the autoantigen of pancreatic antibodies in Crohn's disease
Roggenbuck, Dirk; Hausdorf, Gert; Martinez-Gamboa, Lorena; Reinhold, Dirk; Büttner, Thomas; Jungblut, Peter R.; Porstmann, Tomas; Laaß, Martin Walter; Henker, Jobst; Büning, Carsten; Feist, Eugen; Conrad, Karsten
In: Gut: the journal of the British Society of Gastroenterology ; an international journal of gastroenterology and hepatology / ed. Sheila Sherlock: the journal of the British Society of Gastroenterology ; an international journal of gastroenterology and hepatology - London: BMJ Publishing Group, 1960, Bd. 58.2009, 12, S. 1620-1628
Role of dipeptidyl peptidase IV (DP IV)-like enzymes in T lymphocyte activation: investigations in DP IV/CD26-knockout mice
Reinhold, Dirk; Goihl, Alexander; Wrenger, Sabine; Reinhold, Annegret; Kühlmann, Ulrike C.; Faust, Jürgen; Neubert, Klaus; Thielitz, Anja; Brocke, Stefan; Täger, Michael; Ansorge, Siegfried; Bank, Ute
In: Clinical chemistry and laboratory medicine - Berlin : de Gruyter, Bd. 47 (2009), Heft 3, S. 268-274
Increased blood plasma concentrations of TGF-[beta]1 and TGF-[beta]2 after treatment with intravenous immunoglobulins in childhood autoimmune diseases
Rißmann, Anke; Pieper, Stefanie; Adams, Ines; Brune, Thomas; Wiemann, Dagobert; Reinhold, Dirk
In: Pediatric allergy and immunology - Oxford : Wiley-Blackwell, Bd. 20 (2009), Heft 3, S. 261-265
2008
Non-substrate peptides influencing dipeptidyl peptidase IV/CD26 activity and immune cell function
Wrenger, Sabine; Faust, Jürgen; Mrestani-Klaus, Carmen; Brandt, Wolfgang; Thielitz, Anja; Neubert, Klaus; Reinhold, Dirk
In: Frontiers in bioscience - Searington, NY, Bd. 13 (2008), Heft 9, S. 3194-3201
Inhibitors of dipeptidyl peptidase IV-like activity mediate antifibrotic effects in normal and keloid-derived skin fibroblasts
Thielitz, Anja; Vetter, Robert W.; Schultze, Bianca; Wrenger, Sabine; Simeoni, Luca; Ansorge, Siegfried; Neubert, Klaus; Faust, Jürgen; Lindenlaub, Petra; Gollnick, Harald; Reinhold, Dirk
In: The journal of investigative dermatology - New York, NY : Elsevier, Bd. 128 (2008), Heft 4, S. 855-866
Inflammatory bowel diseases: multiple benefits from therapy with dipeptidyl- and alanyl-aminopeptidase inhibitors
Bank, Ute; Bohr, Ulrich R. M.; Reinhold, Dirk; Lendeckel, Uwe; Ansorge, Siegfried; Malfertheiner, Peter; Täger, Michael
In: Frontiers in bioscience - Searington, NY, Bd. 13 (2008), Heft 10, S. 3699-3713
DP IV/CD26, APN/CD13 and related enzymes as regulators of T cell immunity: implications for experimental encephalomyelitis and multiple sclerosis
Reinhold, Dirk; Bank, Ute; Täger, Michael; Ansorge, Siegfried; Wrenger, Sabine; Thielitz, Anja; Lendeckel, Uwe; Faust, Jürgen; Neubert, Klaus; Brocke, Stefan
In: Frontiers in bioscience - Searington, NY, Bd. 13 (2008), Heft 6, S. 2356-2363
The ectopeptidases dipeptidyl peptidase IV (DP IV) and aminopeptidase N (APN) and their related enzymes as possible targets in the treatment of skin diseases
Thielitz, Anja; Ansorge, Siegfried; Bank, Ute; Täger, Michael; Wrenger, Sabine; Gollnick, Harald; Reinhold, Dirk
In: Frontiers in bioscience - Searington, NY, Bd. 13 (2008), Heft 6, S. 2364-2375
2007
Inhibitors of dipeptidyl peptidase IV and aminopeptidase N target major pathogenetic steps in acne initiation
Thielitz, Anja; Reinhold, Dirk; Vetter, Robert; Bank, Ute; Helmuth, Martin; Hartig, Roland; Wrenger, Sabine; Wiswedel, Ingrid; Lendeckel, Uwe; Kähne, Thilo; Neubert, Klaus; Faust, Jürgen; Zouboulis, Christos C.; Ansorge, Siegfried; Gollnick, Harald
In: The journal of investigative dermatology - New York, NY : Elsevier, Bd. 127 (2007), Heft 5, S. 1042-1051
Dual inhibition of dipeptidyl peptidase IV and aminopeptidase N suppresses inflammatory immune responses
Reinhold, Dirk; Biton, Aliza; Goihl, Alexander; Pieper, Stefanie; Lendeckel, Uwe; Faust, Jürgen; Neubert, Klaus; Bank, Ute; Täger, Michael; Ansorge, Siegfried; Brocke, Stefan
In: Annals of the New York Academy of Sciences/ New York Academy of Sciences - Hoboken, NJ: Wiley Subscription Services, Bd. 1110 (2007), S. 402-409
A new line immunoassay for the multiparametric detection of antiganglioside autoantibodies in patients with autoimmune peripheral neuropathies
Conrad, Karsten; Schneider, Hauke; Ziemssen, Tjalf; Talaska, Thomas; Reinhold, Dirk; Humbel, Rene-Louis; Roggenbuck, Dirk
In: Autoimmunity ; Pt. A:Basic principles and new diagnostic tools / ed. by M. Eric Gershwin and Yehuda Shoenfeld - Boston, Mass.: Blackwell Publ., Bd. 1109 (2007), S. 256-264
A new line immunoassay for the multiparametric detection of antiganglioside autoantibodies in patients with autoimmune peripheral neuropathies
Conrad, Karsten; Schneider, Hauke; Ziemssen, Tjalf; Talaska, Thomas; Reinhold, Dirk; Humbel, Rene-Louis; Roggenbuck, Dirk
In: Autoimmunity ; Pt. A: Basic principles and new diagnostic tools - Boston, Mass. : Blackwell Publ. ; Shoenfeld, Yehuda, Bd. 1109 (2007), S. 256-264
TGF-[beta]1-mediated control of central nervous system inflammation and autoimmunity through the inhibitory receptor CD26
Preller, Vera; Gerber, Annegret; Wrenger, Sabine; Togni, Mauro; Marguet, Didier; Tadje, Janine; Lendeckel, Uwe; Röcken, Christoph; Faust, Jürgen; Neubert, Klaus; Schraven, Burkhart; Martin, Roland; Ansorge, Siegfried; Brocke, Stefan; Reinhold, Dirk
In: The journal of immunology - Rockville, Md. : American Association of Immunologists, Bd. 178 (2007), Heft 7, S. 4632-4640
TGF-[beta]1-mediated control of central nervous system inflammation and autoimmunity through the inhibitory receptor CD26
Preller, Vera; Gerber, Annegret; Wrenger, Sabine; Togni, Mauro; Marguet, Didier; Tadje, Janine; Lendeckel, Uwe; Röcken, Christoph; Faust, Jürgen; Neubert, Klaus; Schraven, Burkhart; Martin, Roland; Ansorge, Siegfried; Brocke, Stefan; Reinhold, Dirk
In: The journal of immunology - Rockville, Md.: American Association of Immunologists, Bd. 178 (2007), 7, S. 4632-4640
Deletion of the LIME adaptor protein minimally affects T and B cell development and function
Grégoire, Claude; Simova, Sarka; Wang, Ying; Sansoni, Amandine; Richelme, Sylvie; Schmidt-Giese, Anja; Simeoni, Luca; Angelisova, Pavla; Reinhold, Dirk; Schraven, Burkhart; Horejsi, Vaclav; Malissen, Bernard; Malissen, Marie
In: European journal of immunology - Weinheim: Wiley, Bd. 37 (2007), 11, S. 3259-3269
Deletion of the LIME adaptor protein minimally affects T and B cell development and function
Grégoire, Claude; Simova, Sarka; Wang, Ying; Sansoni, Amandine; Richelme, Sylvie; Schmidt-Giese, Anja; Simeoni, Luca; Angelisova, Pavla; Reinhold, Dirk; Schraven, Burkhart; Horejsi, Vaclav; Malissen, Bernard; Malissen, Marie
In: European journal of immunology - Weinheim : Wiley, Bd. 37 (2007), Heft 11, S. 3259-3269
Inhibition of alanyl-aminopeptidase on CD4+CD25+ regulatory T-cells enhances expression of FoxP3 and TGF-[beta]1 and ameliorates acute colitis in mice
Bank, Ute; Tadje, Janine; Täger, Michael; Wolke, Carmen; Bukowska, Alicja; Ittenson, Annelore; Reinhold, Dirk; Helmuth, Martin; Ansorge, Siegfried; Shakespeare, Ann; Vieth, Michael W.R.; Malfertheiner, Peter; Naumann, Michael; Lendeckel, Uwe
In: International journal of molecular medicine - Athens : Spandidos Publications, Bd. 20 (2007), Heft 4, S. 483-492
Dual inhibition of dipeptidyl peptidase IV and aminopeptidase N suppresses inflammatory immune responses
Reinhold, Dirk; Biton, Aliza; Goihl, Alexander; Pieper, Stefanie; Lendeckel, Uwe; Faust, Jürgen; Neubert, Klaus; Bank, Ute; Täger, Michael; Ansorge, Siegfried; Brocke, Stefan
In: Annals of the New York Academy of Sciences - Hoboken, NJ : Wiley Subscription Services, Bd. 1110 (2007), S. 402-409
2006
Immune peptides related to dipeptidyl aminopeptidase IV/CD26
Ansorge, Siegfried; Reinhold, Dirk
In: Handbook of biologically active peptides - Amsterdam : Elsevier, Academic Press ; Kastin, Abba J. . - 2006, S. 567-572
Immune peptides related to dipeptidyl aminopeptidase IV/CD26
Ansorge, Siegfried; Reinhold, Dirk
In: Handbook of biologically active peptides - Amsterdam: Elsevier, Academic Press; Kastin, Abba J. . - 2006, S. 567-572
Dipeptidyl aminopeptidases - basic science and clinical applications
Lendeckel, Uwe; Reinhold, Dirk; Bank, Ute
In: New York: Springer Science + Business Media, 2006, XXIV, 239 S., Ill, graf. Darst. - (Advances in experimental medicine and biology; 575)Kongress: International Conference on Dipeptidyl Aminopeptidases 2 (Magdeburg : 2005.04.13-15)
Dipeptidyl aminopeptidases - basic science and clinical applications
Lendeckel, Uwe; Reinhold, Dirk; Bank, Ute
In: New York: Springer Science + Business Media, 2006, XXIV, 239 S. - (Advances in experimental medicine and biology; 575), ISBN: 978-0-387-29058-4 Kongress: International Conference on Dipeptidyl Aminopeptidases 2 Magdeburg 2005.04.13-15
Triggering endogenous immunosuppressive mechanisms by combined targeting of Dipeptidyl peptidase IV (DPIV/CD26) and Aminopeptidase N (APN/ CD13) - a novel approach for the treatment of inflammatory bowel disease
Bank, Ute; Heimburg, Anke; Helmuth, Martin; Stefin, Sofia; Lendeckel, Uwe; Reinhold, Dirk; Faust, Jürgen; Fuchs, Petra; Sens, Bianca; Neubert, Klaus; Täger, Michael; Ansorge, Siegfried
In: International immunopharmacology - Amsterdam [u.a.] : Elsevier, Bd. 6 (2006), Heft 13/14, S. 1925-1934
Increased concentrations of transforming growth factor [beta]1 and [beta]2 in the plasma of patients with glioblastoma
Schneider, Thomas; Sailer, Michael; Ansorge, Siegfried; Firsching, Raimund; Reinhold, Dirk
In: Journal of neuro-oncology - Dordrecht : Springer, Bd. 79 (2006), Heft 1, S. 61-65
Increased concentrations of transforming growth factor [beta]1 and [beta]2 in the plasma of patients with glioblastoma
Schneider, Thomas; Sailer, Michael; Ansorge, Siegfried; Firsching, Raimund; Reinhold, Dirk
In: Journal of neuro-oncology - Dordrecht: Springer, Bd. 79 (2006), 1, S. 61-65
Normal T-cell development and immune functions in TRIM-deficient mice
Kölsch, Uwe; Arndt, Börge; Reinhold, Dirk; Lindquist, Jonathan A.; Jüling, Nicole; Kliche, Stefanie; Pfeffer, Klaus; Bruyns, Eddy; Schraven, Burkhart; Simeoni, Luca
In: Molecular and cellular biology: MCB / American Society for Microbiology - Washington, DC: American Society for Microbiology, Bd. 26 (2006), Heft 9, S. 3639-3648
Dipeptidyl peptidase IV (DP IV, CD26) and aminopeptidase N (APN, CD13) as regulators of T cell function and targets of immunotherapy in CNS inflammation
Reinhold, Dirk; Biton, Aliza; Pieper, Stefanie; Lendeckel, Uwe; Faust, Jürgen; Neubert, Klaus; Bank, Ute; Täger, Michael; Ansorge, Siegfried; Brocke, Stefan
In: International immunopharmacology - Amsterdam [u.a.] : Elsevier, Bd. 6 (2006), Heft 13/14, S. 1935-1942
Attractin, a dipeptidyl peptidase IV/CD26-like enzyme, is expressed on human peripheral blood monocytes and potentially influences monocyte function
Wrenger, Sabine; Faust, Jürgen; Friedrich, Daniel; Hoffmann, Torsten; Hartig, Roland; Lendeckel, Uwe; Kähne, Thilo; Thielitz, Anja; Neubert, Klaus; Reinhold, Dirk
In: Journal of leukocyte biology - Bethesda, Md. : FASEB, Bd. 80 (2006), Heft 3, S. 621-629
Triggering endogenous immunosuppressive mechanisms by combined targeting of Dipeptidyl peptidase IV (DPIV/CD26) and Aminopeptidase N (APN/ CD13) - a novel approach for the treatment of inflammatory bowel disease
Bank, Ute; Heimburg, Anke; Helmuth, Martin; Stefin, Sofia; Lendeckel, Uwe; Reinhold, Dirk; Faust, Jürgen; Fuchs, Petra; Sens, Bianca; Neubert, Klaus; Täger, Michael; Ansorge, Siegfried
In: International immunopharmacology - Amsterdam [u.a.]: Elsevier, Bd. 6 (2006), 13/14, S. 1925-1934
Normal T-cell development and immune functions in TRIM-deficient mice
Kölsch, Uwe; Arndt, Börge; Reinhold, Dirk; Lindquist, Jonathan A.; Jüling, Nicole; Kliche, Stefanie; Pfeffer, Klaus; Bruyns, Eddy; Schraven, Burkhart; Simeoni, Luca
In: Molecular and cellular biology - Washington, DC : American Society for Microbiology, Bd. 26 (2006), Heft 9, S. 3639-3648
Attractin, a dipeptidyl peptidase IV/CD26-like enzyme, is expressed on human peripheral blood monocytes and potentially influences monocyte function
Wrenger, Sabine; Faust, Jürgen; Friedrich, Daniel; Hoffmann, Torsten; Hartig, Roland; Lendeckel, Uwe; Kähne, Thilo; Thielitz, Anja; Neubert, Klaus; Reinhold, Dirk
In: Journal of leukocyte biology: cellular and molecular mechanisms of host defense and inflammation / publ. by the Federation of American Societies for Experimental Biology - Bethesda, Md.: FASEB, Bd. 80 (2006), 3, S. 621-629
Possible role of DP IV inhibitors in acne therapy
Thielitz, Anja; Reinhold, Dirk; Vetter, Robert; Lendeckel, Uwe; Kähne, Thilo; Bank, Ute; Helmuth, Martin; Neubert, Klaus; Faust, Jürgen; Hartig, Roland; Wrenger, Sabine; Zouboulis, Christos C.; Ansorge, Siegfried; Gollnick, Harald
In: Dipeptidyl aminopeptidases - New York: Springer Science + Business Media, 2006 . - 2006, S. 163-167
Dipeptidylpeptidase IV (DPIV) and alanyl-aminopeptidases (AAPs) as a new target complex for treatment of autoimmune and inflammatory diseases - proof of concept in a mouse model of colitis
Bank, Ute; Tadje, Janine; Helmuth, Martin; Stefin, Sofia; Täger, Michael; Wolke, Carmen; Wischeropp, Anke; Ittenson, Annelore; Reinhold, Dirk; Ansorge, Siegfried; Lendeckel, Uwe
In: Dipeptidyl aminopeptidases - New York: Springer Science + Business Media, 2006 . - 2006, S. 143-153
CD26/DP IV in T cell activation and autoimmunity
Preller, Vera; Gerber, Annegret; Togni, Mauro; Wrenger, Sabine; Schraven, Burkhart; Röcken, Christoph; Marguet, Didier; Ansorge, Siegfried; Brocke, Stefan; Reinhold, Dirk
In: Dipeptidyl aminopeptidases - New York: Springer Science + Business Media, 2006 . - 2006, S. 187-193
CD26/DP IV in T cell activation and autoimmunity
Preller, Vera; Gerber, Annegret; Togni, Mauro; Wrenger, Sabine; Schraven, Burkhart; Röcken, Christoph; Marguet, Didier; Ansorge, Siegfried; Brocke, Stefan; Reinhold, Dirk
In: Dipeptidyl aminopeptidases - basic science and clinical applications , 1. Ed. - New York : Springer Science + Business Media , 2006, S. 187-193
Dipeptidyl peptidase IV (DP IV, CD26) and aminopeptidase N (APN, CD13) as regulators of T cell function and targets of immunotherapy in CNS inflammation
Biton, Aliza; Bank, Ute; Täger, Michael; Ansorge, Siegfried; Reinhold, Dirk; Lendeckel, Uwe; Brocke, Stefan
In: Dipeptidyl aminopeptidases - New York: Springer Science + Business Media, 2006 . - 2006, S. 177-186
Expression of dipeptidyl peptidase IV-like enzymes in human peripheral blood mononuclear cells
Wrenger, Sabine; Guth, Bianca; Schultze, Bianca; Hoffmann, Torsten; Friedrichs, Daniela; Kähne, Thilo; Faust, Jürgen; Neubert, Klaus; Reinhold, Dirk
In: Dipeptidyl aminopeptidases - basic science and clinical applications , 1. Ed. - New York : Springer Science + Business Media , 2006, S. 87-91
Expression of dipeptidyl peptidase IV-like enzymes in human peripheral blood mononuclear cells
Wrenger, Sabine; Guth, Bianca; Schultze, Bianca; Hoffmann, Torsten; Friedrich, Daniel; Kähne, Thilo; Faust, Jürgen; Neubert, Klaus; Reinhold, Dirk
In: Dipeptidyl aminopeptidases - New York: Springer Science + Business Media, 2006 . - 2006, S. 87-91
2005
Soluble vascular endothelial growth factor, soluble VEGF receptor Flt-1 and endothelial function in healthy smokers.
Schmidt-Lucke, Caroline; Belgore, F.; Reinhold, Dirk; Ansorge, Siegfried; Klein, Helmut; Schmidt-Lucke, Jan Andre; Lip, G.
In: Int. J. Cardiol. 100(2005), Nr. 2, S. 207 - 212
2004
Increased blood plasma concentrations of TGF-beta isoforms after treatment with intravenous immunoglobulins (IVIG) in patients with multiple sclerosis.
Reinhold, Dirk; Perlov, E.; Schrecke, Kirstin; Kekow, Joern; Brune, Thomas; Sailer, Michael
In: J. Neuroimmunol. 152(2004), Nr. 1-2, S. 191 - 194
2003
Specific inhibition of dipeptidyl peptidase IV (CD26) enzymatic activity - a new approach to psoriasis therapy?.
Vetter, Robert; Reinhold, Dirk; Buehling, Frank; Lendeckel, Uwe; Born, I.; Faust, J.; Neubert, K.; Ansorge, Siegfried; Gollnick, Harald
In: Bonnekoh, B. (Ed.) ; Gollnick, H. (Ed.): Clinico-experimental advances in dermatological diagnostics and treatment : the proceedings of two scientific workshops, organized in the years 2000 and 2001 by the Department of Dermatology and Venerology, Otto-von-Guericke- University Magdeburg. 1. Aufl. Melsungen : Bibliomed, 2003, S. 113 - 119
Immunomodulatory effects of zinc.
Reinhold, Dirk; Ansorge, Siegfried; Gruengreiff, K.
In: Bonnekoh, B. (Ed.) ; Gollnick, H. (Ed.): Clinico-experimental advances in dermatological diagnostics and treatment : the proceedings of two scientific workshops, organized in the years 2000 and 2001 by the Department of Dermatology and Venerology, Otto-von-Guericke- University Magdeburg. 1. Aufl. Melsungen : Bibliomed, 2003, S. 157 - 162
Dipeptidyl peptidase IV inhibitors with the N-terminal MXP sequence : structure-activity- relationships.
Faust, J.; Fuchs, P.; Wrenger, Sabine; Reinhold, Dirk; Stoeckel Maschek, A.; Kaehne, Thilo; Ansorge, Siegfried; Neubert, K.
In: Hildebrandt, M. (Ed.) ; Klapp, B. (Ed.) ; ... (Ed.): Dipeptidyl aminopeptidases in health and disease. New York [u.a.] : Kluwer Academic/Plenum Publ., 2003, S. 175 - 179 (Advances in experimental medicine and biology ; 524)
Propolis and some of its constituents down-regulate DNA synthesis and inflammatory cytokine production but induce TGF-ß1 production of human immune cells.
Ansorge, S.; Reinhold, Dirk; Lendeckel, Uwe
In: Z. Naturforsch. C 58c(2003), Nr. 7/8, S. 580 - 589
2002
Protein kinase C and ERK activation are required for TFF-peptide-stimulated bronchial epithelial cell migration and tumor necrosis factor-alpha-induced interleukin-6 (IL-6) and IL- 8 secretion.
Graness, Angela; Chwieralski, Caroline; Reinhold, Dirk; Thim, L.; Hoffmann, Werner
In: keine Angabe