Prof. Brunner-Weinzierl

Prof. Dr. rer. nat. Monika Brunner-Weinzierl
Forschungslabor (KPAE)
Aktuelle Projekte
- Entwicklung eines Test zur Diagnostik von Immunkompetenz bei SeniorInnen mit Hilfe von Data-mining Methoden (ImmunLearning)
Laufzeit: 01.03.2018 - 31.12.2022 - Antifungal T-cell responses of neonates, infants, and children
Laufzeit: 01.11.2019 - 31.12.2022 - MEMoRIAL: The international Graduate School for Medical Engineering and Engineering Materials
Laufzeit: 01.09.2016 - 30.04.2022 - Entwicklung eines Tests zur Diagnostik von Immunkompetenz bei Senior*innen mit Hilfe von Data-mining-Methoden (ImmunLearning)
Laufzeit: 01.01.2019 - 31.03.2022 - TP4: Staphylococcus aureus-induziertes Mikromilieu beim Neonatenund Kleinkind und seine Rolle bei Neoplasie. Else Kröner Forschungskolleg
Laufzeit: 01.01.2016 - 31.12.2021 - CTLA-4-(CD152)-induced signalling pathways as regulators of CD8+ T lymphocytes (SFB854 B14)
Laufzeit: 01.01.2014 - 31.12.2021 - Die Bedeutung des inflammatorischen Mikromilieus für die Krebsentstehung
Laufzeit: 01.01.2018 - 31.12.2021 - Charakterisierung und therapeutische Expansion der protektiven Effektor- und Gedächtnis-T-Zell-Antworten gegen SARS-CoV-2
Laufzeit: 01.06.2020 - 31.12.2021 - ABINEP Zentralprojekt
Laufzeit: 01.04.2017 - 31.10.2021
Abgeschlossene Projekte
- Zentrale Faktoren der Immunantwort zur Abwehr von Sars-CoV-2
Laufzeit: 01.01.2020 - 31.12.2020 - YB-1 bei chronischen T-Zellantworten und Systemischer Lupus Erthematodes (SLE)
Laufzeit: 01.08.2016 - 31.08.2019 - Steuerung der Gedächtnisbildung von Allergien
Laufzeit: 15.03.2014 - 30.11.2018 - The role of the cold-shock protein YB-1 in hyperproliferation of leukemic T cell blasts
Laufzeit: 01.01.2015 - 31.12.2017 - Induction and characterization of bacterial and fungal-specific T-cell responses
Laufzeit: 01.01.2015 - 31.12.2017 - CTLA-4 induced signal transduction in CD8 T-cell differentiation: Implications for tumour-checkpoint therapy
Laufzeit: 01.01.2015 - 28.12.2017 - Immunregulation von Th2 Gedächtniszellen bei Allergie
Laufzeit: 01.10.2011 - 30.09.2015 - CD152(CTLA-4-initiierte Signalwege bei der Differenzierung von T-Zellen
Laufzeit: 01.01.2010 - 31.12.2014 - CD152 (CTLA-4) bei der B-Zelldifferenzierung
Laufzeit: 01.09.2009 - 30.03.2013 - Natürliche Mechanismen der Immunregulation bei Neugeborenen, Säuglingen und Kleinkindern
Laufzeit: 15.08.2009 - 31.12.2011 - CTLA-4 sensibilisiert T Zellen für Migration
Laufzeit: 01.01.2006 - 21.01.2010 - CD28 unabhängige Signaltransduktion von CTLA-4 in CD28null T-Zellen
Laufzeit: 01.04.2007 - 31.12.2009 - Das frühkindlichen, adataptive Immunsystem: Nährboden für Immunpathologien?
Laufzeit: 15.01.2008 - 15.11.2009 - Das immunologische Gedächtnis beim Neugeborenen und Kleinkind - Fluch oder Segen?
Laufzeit: 22.01.2008 - 22.01.2009 - Immunregulation von Th2 Lymphozyten bei atopischer Dermatitis
Laufzeit: 01.03.2007 - 30.09.2008
2021
Begutachteter Zeitschriftenartikel
Plasma membrane Ca2+ ATPase 1 (PMCA1) but not PMCA4 is critical for B-cell development and Ca2+ homeostasis in mice
In: European journal of immunology - Weinheim: Wiley-VCH, 1971, Bd. 51 (2021), 3, S. 594-602
2020
Begutachteter Zeitschriftenartikel
YB-1 interferes with TNFα-TNFR binding and modulates progranulin-mediated inhibition of TNFα signaling
In: International journal of molecular sciences - Basel: Molecular Diversity Preservation International, 2000, Vol. 21.2020, 19, Art.-Nr. 7076, insgesamt 17 Seiten
Children from the age of three show a developmental switch in T-cell differentiation
In: Frontiers in immunology - Lausanne: Frontiers Media, 2010, Vol. 11.2020, Art.-Nr. 1640, insgesamt 12 Seiten
Cell survival failure in effector T cells from patients with systemic lupus erythematosus following insufficient upregulation of coldshock Ybox binding protein 1
In: Arthritis & rheumatology: an official journal of the American College of Rheumatology - Hoboken, NJ: Wiley, 2014, Bd. 72.2020, 10, S. 1721-1733
CTLA-4-competent conventional T-cells back up regulatory T-cells to restrain memory T-helper type 2 cell responses. Letter to the editor
In: Allergy - Oxford: Wiley, 1978, Bd. 75.2020, 3, S. 684-687
2019
Begutachteter Zeitschriftenartikel
Aktuelle Entwicklungen in der Allergieprävention
In: Consilium: Mitteilungen der Ärztekammer für Niederösterreich - Wien: Ärztekammer für Niederösterreich, Körperschaft Öffentlichen Rechts, Bd. 74.2019, 11, S. 26-31
CTLA-4 (CD152) - a versatile receptor for immune-based therapy
In: Seminars in immunology - London: Academic Press, Bd.42.2019, Art.-Nr. 101298
IFN-γ is a therapeutic target in paraneoplastic cerebellar degeneration
In: JCI insight - Ann Arbor, Michigan: JCI Insight, Bd. 4.2019, 7, Art.-Nr. e127001, insges. 12 S.
2018
Begutachteter Zeitschriftenartikel
CTLA-4 and PD-1 control of T-cell motility and migration - implications for tumor immunotherapy
In: Frontiers in immunology - Lausanne: Frontiers Media, Bd. 9.2018, Art.-Nr. 2737, insges. 8 S.
Paradigmenwechsel in der Allergieprävention
In: Monatsschrift Kinderheilkunde: Organ der Deutschen Gesellschaft für Kinderheilkunde - Berlin: Springer, Bd. 166.2018, 8, S. 708-713
Developmental induction of human T-cell responses against Candida albicans and Aspergillus fumigatus
In: Scientific reports - [London]: Macmillan Publishers Limited, part of Springer Nature, Bd. 8.2018, Art.-Nr. 16904, insges. 14 S.
2017
Abstract
CTLA-4 mediated effects on STATs regulate differentiation and plasticity of Tc17 cells
In: European journal of immunology - Weinheim: Wiley VCH, 1971, Bd. 47.2017, Suppl. 2, P395, S. 277
Bacteria-specific CD4+T-cell responses of neonates, infants and adults show age-dependent characteristics
In: European journal of immunology - Weinheim: Wiley VCH, 1971, Bd. 47.2017, Suppl. 2, P357, S. 264
Begutachteter Zeitschriftenartikel
The differentiation and plasticity of Tc17 cells are regulated by CTLA-4-mediated effects on STATs
In: OncoImmunology - Abingdon: Taylor & Franics, 2012, Bd. 6.2017, 2, Art.-Nr. e1273300, insges. 5 S.
Inflammatory cell infiltration and resolution of kidney inflammation is orchestrated by the cold-shock protein Y-box binding protein-1
In: Kidney international: official journal of the International Society of Nephrology - New York, NY: Elsevier, 1972, Bd. 92.2017, 5, S. 1157-1177
RSK-mediated nuclear accumulation of the cold-shock Y-box protein-1 controls proliferation of T cells and T-ALL blasts
In: Cell death and differentiation - Houndmills, Basingstoke: Nature Publishing Group, 1997, Bd. 24.2017, 2, S. 371-383
CTLA-4-mediated posttranslational modifications direct cytotoxic T-lymphocyte differentiation
In: Cell death and differentiation - Houndmills, Basingstoke: Nature Publishing Group, Bd. 24.2017, 10, S. 1739-1749
Activated protein C protects from GvHD via PAR2/PAR3 signalling in regulatory T-cells
In: Nature Communications - [London]: Nature Publishing Group UK, 2010, 8(2017) Artikel-Nummer 311, 16 Seiten
Buchbeitrag
Adaptives Immunsystem
In: Fetoneonatale Infektiologie- Stuttgart: Georg Thieme Verlag, 2017, S. 27-34
Angeborenes Immunsystem von Fötus, Neonaten und Kleinkind
In: Fetoneonatale Infektiologie- Stuttgart: Georg Thieme Verlag, 2017, S. 23-27
Eingeschränkte Immunabwehr gegen bekapselte Bakterien
In: Fetoneonatale Infektiologie- Stuttgart: Georg Thieme Verlag, 2017, S. 36
Hygienehypothese
In: Fetoneonatale Infektiologie- Stuttgart: Georg Thieme Verlag, 2017, S. 34-35
Dissertation
CTLA-4 induced signal transduction in regulating differentiation and plasticity of Tc17 cells
In: Magdeburg, 2017, x, 84 Blätter, Illustrationen ; [Literaturverzeichnis: Blatt 63-79]
2016
Abstract
CD4+ T cells from human neonates and infants respond variously against antigens of Staphylococcus aureus, but not against Bifidobacter longum ssp. infantis
In: The journal of immunology: official journal of the American Association of Immunologists- Rockville, Md: American Association of Immunologists, 1916, Bd. 196.2016, 1 Suppl., Abs. 66.24, insges. 1 S.
CTLA-4-targeted proteins in differentiating CD8+ T lymphocytes
In: The journal of immunology: official journal of the American Association of Immunologists - Rockville, Md.: American Association of Immunologists, 1916, Bd. 196.2016, 1 Suppl., Abs. 72.19, insges. 1 S.
Plasticity along with differentiation of Tc17 cells is controlled by CTLA-4 (CD152)
In: The journal of immunology: official journal of the American Association of Immunologists - Rockville, Md.: American Association of Immunologists, 1916, Bd. 196.2016, 1 Suppl., Abs. 133.15, insges. 1 S.
Implikationen für allergische Erkrankungen - CTLA-4-Signale beeinflussen nachhaltig TH2-Immunantworten
In: Allergologie: immunbiologische Grundlagen ; Diagnostik und Therapie für Praxis und Klinik ; Organ der Deutschen Gesellschaft für Allergie- und Immunitätsforschung und des Ärzteverbandes Deutscher Allergologen - München-Deisenhofen [i.e.] Deisenhofen: Dustri-Verl. Feistle, 1978, Bd. 39 (2016), 5, S. 225
Intrinsic- and extrinsic- mediated CTLA-4-signals shape the TH2 response - implications for allergic disorders
In: European journal of immunology - Weinheim: Wiley, 1971, Bd. 46.2016, Suppl. 1, Abs. 3557, Seite 1053
Charakterisierung infektionsspezifischer T-Zell-Antworten bei Neugeborenen und Kleinkindern
In: Allergologie: immunbiologische Grundlagen ; Diagnostik und Therapie für Praxis und Klinik ; Organ der Deutschen Gesellschaft für Allergie- und Immunitätsforschung und des Ärzteverbandes Deutscher Allergologen - München-Deisenhofen [i.e.] Deisenhofen: Dustri-Verl. Feistle, 1978, Bd. 39.2016, 5, S. 227-228
Begutachteter Zeitschriftenartikel
Early changes in the metabolic profile of activated CD8+ T cells
In: BMC cell biology - London: BioMed Central, 2000, Bd. 17.2016, Art.-Nr. 28, insges. 11 S.
T cells of infants are mature, but hyporeactive due to limited Ca2+ influx
In: PLOS ONE - San Francisco, California, US: PLOS, 2006, Bd. 11.2016, 11, Art.-Nr. e0166633, insges. 27 S.
CTLA4 blockade elicits paraneoplastic neurological disease in a mouse model
In: Brain - Oxford: Oxford Univ. Press, 1878, Bd. 139 (2016), 11, S. 2923-2934
2014
Begutachteter Zeitschriftenartikel
CD4+ T cells from human neonates and infants are poised spontaneously to run a nonclassical IL-4 program
In: The journal of immunology - Bethesda, Md: Soc, 1916, Bd. 192.2014, 11, S. 5160-5170
CTLA-4 (CD152) enhances the Tc17 differentiation program
In: European journal of immunology - Weinheim: Wiley-VCH, 1971, Bd. 44.2014, 7, S. 2139-2152
Autoimmune pancreatitis in MRL/Mp mice is a T cell-mediated disease responsive to cyclosporine A and rapamycin treatment
In: Gut - London: BMJ Publishing Group, 1960, Bd. 63.2014, 3, S. 494-505
CTLA-4 is expressed by activated mouse NK cells and inhibits NK cell IFN-[gamma] production in response to mature dendritic cells
In: The journal of immunology. - Bethesda, Md : Soc, Bd. 192.2014, 9, S. 4184-4191
Clinically relevant doses of FLT3-kinase inhibitors Quizartinib and Midostaurin do not impair T-cell reactivity and function
In: Haematologica: journal of the European Hematology Association - Pavia: Ferrata Storti Foundation, Bd. 99.2014, 6, S. e90-e93
2013
Begutachteter Zeitschriftenartikel
Acute psychological stress increases peripheral blood CD3+CD56+ natural killer T cells in healthy men: possible implications for the development and treatment of allergic and autoimmune disorders
In: Stress : the international journal on the biology of stress. - London : Informa Healthcare, Bd. 16.2013, 4, S. 421-428
Immune privilege as an intrinsic CNS property - astrocytes protect the CNS against T-cell-mediated neuroinflammation
In: Mediators of inflammation. - Sylvania, Ohio : Hindawi Publishing Corp; 2013, Article ID 320519, insges. 11 S.
Das neonatale Immunsystem - Modulation durch regulatorische T-Zellen und CTLA-4 (CD152) : modulation by regulatory T-cells and CTLA-4
In: Laboratoriumsmedizin - Berlin [u.a.]: de Gruyter, 1977, Bd. 37.2013, 3, S. 123-129
Impact of the CTLA-4/CD28 axis on the processes of joint inflammation in rheumatoid arthritis
In: Arthritis & rheumatism: an official journal of the American College of Rheumatology - Hoboken, NJ: Wiley-Blackwell, 1958, Bd. 65.2013, 1, S. 81-87
PAG/Cbp suppression reveals a contribution of CTLA-4 to setting the activation threshold in T cells
In: Cell communication and signaling - London: Biomed Central, 2003, Bd. 11.2013, Art.-Nr. 28, insges. 13 S.
Dissertation
Untersuchung des Einflusses der Histon-H3K9-Acetylierung auf die Prognose beim Neuroblastom
In: Magdeburg, Univ., Med. Fak., Diss., 2013; XVIII, 53 Bl: Ill., graph. Darst.
2012
Originalartikel in begutachteter internationaler Zeitschrift
Migration of Th1 lymphocytes is regulated by CD152 (CTLA-4)-mediated signaling via PI3 kinase-dependent Akt activation
In: PLOS ONE - San Francisco, California, US: PLOS, 2006, Bd. 7.2012, 3, Artikel-Nr. e31391, insges. 9 S.
Activation of the Hippo pathway by CTLA-4 regulates the expression of Blimp-1 in the CD8+ T cell
In: Proceedings of the National Academy of Sciences of the United States of America - Washington, DC: National Acad. of Sciences, 1915, Bd. 109.2012, 33, S. E2223-E2229
Pro-inflammatory effector Th cells transmigrate through anti-inflammatory environments into the murine fetus
In: Placenta - Amsterdam [u.a.]: Elsevier, Bd. 33 (2012), 1, S. 39-46
2011
Dissertation
Einfluss von CD152-Signalen auf das Migrationsverhalten von T H 1-Lymphozyten
In: Magdeburg, Univ., Fak. für Naturwiss., Diss., 2011, 114 Bl., graph. Darst., 30 cm
Originalartikel in begutachteter internationaler Zeitschrift
IL-1[beta] and TGF-[beta] act antagonistically in induction and differentially in propagation of human proinflammatory precursor CD4+ T cells
In: The journal of immunology: official journal of the American Association of Immunologists - Rockville, Md.: American Association of Immunologists, 1916, Bd. 187.2011, 11, S. 5627-5635
CTLA-4 (CD152) blockade does not cause a pro-inflammatory cytokine profile in regulatory T cells
In: Clinical and experimental rheumatology. - Pisa : Pacini, Bd. 29.2011, 2, S. 254-260
Glycogen synthase kinase-3[beta] is a crucial mediator of signal-induced RelB degradation
In: Oncogene: an international journal - New York, NY: Springer Nature, 1987, Bd. 30.2011, 21, S. 2485-2492
Blockade of CTLA-4 decreases the generation of multifunctional memory CD4+ T Cells in vivo
In: The journal of immunology: official journal of the American Association of Immunologists - Rockville, Md.: American Association of Immunologists, 1916, Bd. 186.2011, 10, S. 5580-5589
2010
Originalartikel in begutachteter internationaler Zeitschrift
Decrease of CD4+FOXP3+ T regulatory cells in the peripheral blood of human subjects undergoing a mental stressor
In: Psychoneuroendocrinology . - Oxford [u.a.] : Elsevier, Bd. 35.2010, 5, S. 663-673
CTLA-4 (CD152) inhibits T cell function by activating the ubiquitin ligase Itch
In: Molecular immunology . - Amsterdam [u.a.] : Elsevier, Bd. 47.2010, 10, S. 1875-1881
Female-biased incidence of experimental autoimmune encephalomyelitis reflects sexually dimorphic expression of surface CTLA-4 (CD152) on T lymphocytes
In: Gender medicine . - Hillsborough, NJ : Excerpta Medica, Bd. 7.2010, 4, S. 296-308
2009
Originalartikel in begutachteter internationaler Zeitschrift
CD152 (CTLA-4) regulates effector functions of CD8+ T lymphocytes by repressing Eomesodermin
In: European journal of immunology . - Weinheim : Wiley VCH, Bd. 39.2009, 3, S. 883-893
Surface CD152 (CTLA-4) expression and signaling dictates longevity of CD28null T cells
In: The journal of immunology . - Bethesda, Md. : American Assoc. of Immunologists, Bd. 182.2009, 9, S. 5342-5351
CD152 (CTLA-4) determines CD4 T cell migration in vitro and in vivo
In: PLoS one . - Lawrence, Kan. : PLoS, Bd. 4.2009, 5, insges. 11 S.
CTLA-4 (CD152) controls homeostasis and suppressive capacity of regulatory T cells in mice
In: Arthritis & rheumatism . - Hoboken, NJ : Wiley-Blackwell, Bd. 60.2009, 1, S. 123-132
2008
Artikel in Zeitschrift
CTLA-4 (CD152) controls homeostasis and suppressive capacity of regulatory T cells in mice
In: Arthritis & rheumatism. - Hoboken, NJ : Wiley-Blackwell, Bd. 60.2008, 1, S. 123-32
2007
Artikel in Zeitschrift
High IFN- Production of Individual CD8 T Lymphocytes Is Controlled by CD152 (CTLA-4)
In: The journal of immunology. - Bethesda, Md : Soc, Bd. 178.2007, 4, S. 2132-2140, unter URL: http://www.jimmunol.org/cgi/content/full/178/4/2132
Originalartikel in begutachteter internationaler Zeitschrift
A new role of CTLA-4 on B cells in thymus-dependent immune responses in vivo
In: The journal of immunology: official journal of the American Association of Immunologists - Rockville, Md: American Association of Immunologists, Bd. 179.2007, 11, S. 7316-7324
2006
Artikel in Zeitschrift
CD25 regulatory T cells determine secondary but not primary remission in EAE: impact on long-term disease progression
In: Journal of neuroimmunology . - Amsterdam : Elsevier, Bd. 172.2006, 1, S. 73-84
- Role of the cold-shock protein YB-1 in Systemic Lupus Erythematodes (SLE)
- Prof. Thomas Fischer, Klinik für Hämatologie und Onkologie, Universitätsklinik Magdeburg
- Christian Freund, Free University Berlin
- Prof. SPILIOPOULOU, Myra, FIN, OVGU
- Dirk Schlüter, OVGU Magdeburg
- Prof. Peter Mertens, OVGU
- Prof. Burkart Schraven, Institut für Immunologie, Universitätsklinikum, OVGU, Magdeburg
- Thomas Fischer, OVGU Magdeburg
- The role of CTLA-4 in allergy prevention
1991 Diploma in Biology
1986-1988 Studies of Informatics, Free University Berlin
1985-1991 Studies of Biology, Free University Berlin and University of Western Australia Perth
2. Advanced academic qualifications
2008 Graduation in Diagnostics of Immunodeficiency and Autoimmunity (DGfI)
since 2007 W2-Professorship of Experimental Pediatrics and Neonatology at the Medical Faculty of the OvGU
2004-2007 C2-Assistant Professor at the Clinic of Internal Medicine, Department of Rheumatology and Clin. Immunology, Charité-Universitätsmedizin (Charité) Berlin
11/03 Venia legendi in Immunology, Free University Berlin
11/03 Habilitation for Immunology, Charité Berlin (mentors Andreas Radbruch, Gerd-Rüdiger Burmester)
08/03 Graduation as Expert in Immunology of the German society of Immunology (DGfI)
03/95 Ph.D. thesis, DRFZ/Free University Berlin, Mentor: Avrion Mitchison
3. Postgraduate professional career
since 04/07 Head (W2) of the Department Experimental Pediatrics and Neonatology of the Clinic of Pediatrics, Medical Faculty, Otto-von-Guericke University Magdeburg
2002-2007 Group leader ¿Molecular Immunology¿ at the Clinic of Internal Medicine, Department of Rheumatology and Clin. Immunology, Charité Berlin
1997-2002 Group leader ¿Molecular Immunology¿ at the Center of Arthritis Research Berlin (DRFZ)
1995-1997 PostDoc at the Department of Molecular and Cellular Biology, University of California, Berkeley, US, mentor: James P. Allison, Nobel price winner 2018
1991-1995 Scientific staff member of the DRFZ, Berlin
5. Other
since 2016 Vice-President of research, technology, and equal opportunity of the Otto-von-Guericke University Magdeburg
2011 Nomination of Rudolph...and Brunner-Weinzierl, 2011, as research highlight of Nature Immunology (Nat Immunol 12:518)
2009 Nomination of Hoff, .., and Brunner-Weinzierl, 2009, J Immunol 182:5342 for the 1000 best publications in medicine (Faculty of 1000)
since 2004 Member of the Audit Committee for ¿Expert in Immunology¿, DGfI
2007 Max Hirsch Lecturer SS07 at the Charité, Berlin
2006-2007 Personal award for the top assistant professors of the Charité, Berlin (top 10% rating)
2004 Award 2004 of the Wolfgang Schulze foundation for the best research
2002-2004 Rahel Hirsch grant for habilitation, Charité Berlin
2003 Award 2003 of the Wolfgang Schulze foundation for the best research
1995-2000 Fellowship (in US and Germany) of the Bundesministerium für Bildung und Forschung, given by the DKFZ, Heidelberg, (now Emmy Nöther program)
1991 Diploma in Biology
1986-1988 Studies of Informatics, Free University Berlin
1985-1991 Studies of Biology, Free University Berlin and University of Western Australia Perth
2. Advanced academic qualifications
2008 Graduation in Diagnostics of Immunodeficiency and Autoimmunity (DGfI)
since 2007 W2-Professorship of Experimental Pediatrics and Neonatology at the Medical Faculty of
the OvGU
2004-2007 C2-Assistant Professor at the Clinic of Internal Medicine, Department of Rheumatology and Clin. Immunology, Charité-Universitätsmedizin (Charité) Berlin
11/03 Venia legendi in Immunology, Free University Berlin
11/03 Habilitation for Immunology, Charité Berlin (mentors Andreas Radbruch, Gerd-Rüdiger
Burmester)
08/03 Graduation as Expert in Immunology of the German society of Immunology (DGfI)
03/95 Ph.D. thesis, DRFZ/Free University Berlin, Mentor: Avrion Mitchison
3. Postgraduate professional career
since 04/07 Head (W2) of the Department Experimental Pediatrics and Neonatology of the Clinic of
Pediatrics, Medical Faculty, Otto-von-Guericke University Magdeburg
2002-2007 Group leader ¿Molecular Immunology¿ at the Clinic of Internal Medicine, Department of
Rheumatology and Clin. Immunology, Charité Berlin
1997-2002 Group leader ¿Molecular Immunology¿ at the Center of Arthritis Research Berlin (DRFZ)
1995-1997 PostDoc at the Department of Molecular and Cellular Biology, University of California,
Berkeley, US (mentor James P. Allison).
1991-1995 Scientific staff member of the DRFZ, Berlin
4. Other
since 2016 Vice-President of research, technology, and equal opportunity of the Otto-von-Guericke
University Magdeburg
2011 Nomination of Rudolph...and Brunner-Weinzierl, 2011, as research highlight of Nature
Immunology (Nat Immunol 12:518)
2009 Nomination of Hoff, .., and Brunner-Weinzierl, 2009, J Immunol 182:5342 for the 1000
best publications in medicine (Faculty of 1000)
since 2004 Member of the Audit Committee for ¿Expert in Immunology¿, DGfI
2007 Max Hirsch Lecturer SS07 at the Charité, Berlin
2006-2007 Personal award for the top assistant professors of the Charité, Berlin (top 10% rating)
2004 Award 2004 of the Wolfgang Schulze foundation for the best research
2002-2004 Rahel Hirsch grant for habilitation, Charité Berlin
2003 Award 2003 of the Wolfgang Schulze foundation for the best research
1995-2000 Fellowship (in US and Germany) of the Bundesministerium für Bildung und Forschung,
given by the DKFZ, Heidelberg, (now Emmy Nöther program)
1991 Diploma in Biology
1986-1988 Studies of Informatics, Free University Berlin
1985-1991 Studies of Biology (Free University Berlin, University of Western Australia at Perth)
2. Advanced academic qualifications
2008 Graduation in Diagnostics of Immunodeficiency and Autoimmunity (DGfI)
since 2007 W2-Professorship of Experimental Pediatrics and Neonatology, Medical Faculty, OVGU
2004-2007 C2-Assistant Professor, Internal Medicin, Charité-Universitätsmedizin Berlin
11/03 Venia legendi in Immunology, Free University Berlin
11/03 Habilitation, Charité Berlin (mentors: Andreas Radbruch, Gerd-Rüdiger Burmester)
08/03 Graduation as Expert in Immunology of the German society of Immunology (DGfI)
03/95 Ph.D. thesis, DRFZ/Free University Berlin, mentor: Avrion Mitchison
3. Postgraduate professional career
since 2016 Vice-President of the OVGU for research, technology and equal opportunity
since 04/07 Head (W2) of the Dep. Exp. Pediatrics and Neonatology, Medical Faculty, OVGU 2002-2007 Group leader ¿Molecular Immunology¿ , Dep. of Rheumatol. and Clin. Immunol., Charité
1997-2002 Group leader ¿Molecular Immunology¿ at the Center of Arthritis Research Berlin (DRFZ)
1995-1997 PostDoc at the Department of Cancer Research, University of California,
Berkeley, US (mentor James P. Allison).
1991-1995 Scientific staff member of the DRFZ, Berlin
- Other
since 2016 Vice-President of the OVGU research, technology, and equal opportunity
2011 Nomination of Rudolph et al., 2011, as research highlight of Nat. Immunol. (12:518)
2009 Nomination of Hoff et al., 2009, for the 1000 best publications in medicine (Faculty of 1000)
since 2004 Member of the Audit Committee for ¿Expert in Immunology¿, DGfI
2007 Max Hirsch Lecturer SS07 at the Charité, Berlin
2006-2007 Personal award for the top assistant professors of the Charité, Berlin (top 10% rating)
2004 Award 2004 of the Wolfgang Schulze foundation for the best research
2002-2004 Rahel Hirsch grant for habilitation, Charité Berlin
2003 Award 2003 of the Wolfgang Schulze foundation for the best research
1995-2000 Fellowship (in US and Germany) of the BMBF given by the DKFZ, Heidelberg, (now Emmy Nöther program)