Publikationen

2019

Begutachteter Zeitschriftenartikel

Gassenmaier, Maximilian;  Keim, Ulrike;  Leiter-Stöppke, Ulrike Martina Barbara;  Eigentler, Thomas Kurt;  Röcken, Martin;  Gesierich, Anja Heike;  Moritz, Rose Kathrin Caroline;  Heinzerling, Lucie;  Tüting, Thomas;  Wollina, Uwe;  Garbe, Claus 

Age as key factor for pattern, timing and extent of distant metastasis in patients with cutaneous melanoma - a study of the German Central Malignant Melanoma Registry
In: Journal of the American Academy of Dermatology - Amsterdam [u.a.]: Elsevier, Bd. 80.2019, 5, S. 1299-1307.e7

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Bender-Saebelkampf, Sophia;  Franke, Ingolf;  Alter, Mareike;  Tueting, Thomas;  Gaffal, Evelyn 

Cutaneous and pulmonary botryomycosis
In: The lancet <London> / Infectious diseases - New York, NY: Elsevier, Bd. 19.2019, 6, S. 670

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Ulrich, Maximilian;  Tinschert, Sigrid;  Siebert, Eberhard;  Franke, Ingolf;  Tüting, Thomas;  Ulrich, Jens;  Schanze, Denny;  Wieland, Ilse;  Zenker, Martin 

Detection of a multilineage mosaic NRAS mutation c.181C>A (p.Gln61Lys) in an individual with a complex congenital nevus syndrome. Letter to the editor
In: Pigment cell & melanoma research - Oxford [u.a.]: Wiley-Blackwell, Bd. 32.2019, 3, S. 470-473

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Annala, Suvi;  Feng, Xiaodong;  Shridhar, Naveen;  Eryilmaz, Funda;  Patt, Julian;  Yang, JuHee;  Pfeil, Eva M.;  Cervantes-Villagrana, Rodolfo Daniel;  Inoue, Asuka;  Häberlein, Felix;  Slodczyk, Tanja;  Reher, Raphael;  Kehraus, Stefan;  Monteleone, Stefania;  Schrage, Ramona;  Heycke, Nina;  Rick, Ulrike;  Engel, Sandra;  Pfeifer, Alexander;  Kolb, Peter;  König, Gabriele M.;  Bünemann, Moritz;  Tüting, Thomas;  Vázquez-Prado, José;  Gutkind, J. Silvio;  Gaffal, Evelyn;  Kostenis, Eva 

Direct targeting of Gαq and Gα11 oncoproteins in cancer cells
In: Science signaling - Washington, DC [u.a.]: Assoc., Bd. 12.2019, 573, eaau5948, insges. 14 S.

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Ruotsalainen, Janne;  Tüting, Thomas 

Live or let die - T cell survival in cancer immunotherapy
In: Immunity - [Cambridge, Mass.]: Cell Press, Bd. 50.2019, 2, S. 280-282

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Braun, Andreas;  Franke, Ingolf;  Tüting, Thomas;  Gaffal, Evelyn 

Pancreatic panniculitis with polyarthritis (PPP syndrome) - clinical letter
In: Journal der Deutschen Dermatologischen Gesellschaft - Berlin: Wiley-Blackwell, Bd. 17.2019, 5, S. 546-547

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Park, Simone L.;  Buzzai, Anthony;  Rautela, Jai;  Hor, Jyh Liang;  Hochheiser, Katharina;  Effern, Maike;  McBain, Nathan;  Wagner, Teagan;  Edwards, Jarem;  McConville, Robyn;  Wilmott, James S.;  Scolyer, Richard A.;  Tüting, Thomas;  Palendira, Umaimainthan;  Gyorki, David;  Mueller, Scott N.;  Huntington, Nicholas D.;  Bedoui, Sammy;  Hölzel, Michael;  Mackay, Laura K.;  Waithman, Jason;  Gebhardt, Thomas 

Tissue-resident memory CD8+ T cells promote melanoma-immune equilibrium in skin
In: Nature <London> - London [u.a.]: Nature Publ. Group, Bd. 565.2019, 7739, S. 366-371, insges. 23 S.

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2018

Abstrakt

Alter, Mareike;  Link, Alexander;  Karoglan, Ante;  Tüting, Thomas;  Canbay, Ali E. 

Alimentäre Beeinflussung des enteralen Mikrobioms durch gezielte Ernährungsberatung bei Melanompatienten unter Immuntherapie und Auswirkungen einer onkologischen Kostform auf die Lebensqualität und das Therapieansprechen
In: Journal der Deutschen Dermatologischen Gesellschaft: JDDG : Organ der Deutschen Dermatologischen Gesellschaft (DDG) und der Österreichischen Gesellschaft für Dermatologie und Venerologie (ÖGDV): JDDG ; Organ der Deutschen Dermatologischen Gesellschaft (DDG) und der Österreichischen Gesellschaft für Dermatologie und Venerologie (ÖGDV)/ Deutsche Dermatologische Gesellschaft - Chichester: Blackwell, Bd. 16.2018, Suppl. 6, P139, S. 82-83

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Shridhar, Naveen;  Ehrlich-Treuenstätt, Gregor;  Bonifatius, Susanne;  Tüting, Thomas;  Gaffal, Evelyn 

Effect of selective Gq/11-inhibition on malignant melanoma
In: Experimental dermatology - Oxford: Wiley-Blackwell, Bd. 27.2018, 3, P185 (OP05/03), S. e81

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Gaffal, Evelyn;  Sluis, Tetje;  Bonifatius, Susanne;  Tüting, Thomas 

Impact of oncogenic BrafV600 on melanoma pathogenesis in Hgf-Cdk4R24C mice
In: Experimental dermatology: the official journal of the European Immunodermatology Society - Oxford: Wiley-Blackwell, Bd. 27.2018, 3, P211, S. e92-e93

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Shridhar, Naveen;  Ruotsalainen, Janne;  Sluis, Tetje;  Rogava, Meri;  Yu, Di;  Essand, Magnus;  Kastenmüller, Wolfgang;  Gaffal, Evelyn;  Tüting, Thomas 

Modifying melanoma immune microenvironment by heterologous prime-boost vaccination with adenovirus and Modified Vaccinia Ankara virus vectors
In: Experimental dermatology - Oxford: Wiley-Blackwell, Bd. 27.2018, 3, P126, S. e54-e55

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Ribas, Antoni;  Mehmi, Inderjit;  Medina, Theresa;  Lao, Christopher;  Kummar, Shivanni;  Amin, Asim;  Deva, Sanjeer;  Salama, April K.;  Tueting, Thomas;  Milhem, Mohammed;  Hoimes, Christopher J.;  Daniels, Gregory;  Shaheen, Montaser;  Jang, Sekwon;  Barve, Minat;  Powell, Alex;  Chandra, Sunandana;  Schmidt, Emmett V.;  Janssen, Robert;  Long, Georgina 

Phase Ib/II study of the combination of SD-101 and pembrolizumab in patients with advanced melanoma who had progressive disease on or after prior anti-PD-1 therapy
In: Annals of oncology- Oxford: Oxford Univ. Press, 1990, Bd. 29.2018, Suppl. 8, 1265P, Seite viii451-viii452

Long, Georgina;  Milhem, Mohammed;  Amin, Asim;  Hoimes, Christopher J.;  Medina, Theresa;  Conry, Robert M.;  Lao, Christopher;  Daniels, Gregory;  Reddy, Sunil;  Mehmi, Inderjit;  Andtbacka, Robert H. I.;  Barve, Minat;  Shaheen, Montaser;  Tueting, Thomas;  Chisamore, Michael;  Xing, Biao;  Candia, Albert;  Gamelin, E.;  Janssen, Robert;  Ribas, Antoni 

Phase Ib/II, open label, multicenter, study of the combination of SD-101 and pembrolizumab in patients with advanced melanoma who are naive to anti-PD-1 therapy
In: Annals of oncology- Oxford: Oxford Univ. Press, 1990, Bd. 29.2018, Suppl. 8, LBA45, Seite viii736

Glodde, Nicole Erika;  Bald, Tobias;  Boorn-Konijnenberg, Debby;  Landsberg, Jennifer Caroline;  Gebhardt, Christoffer;  Long, Georgina;  Kastenmüller, Wolfgang;  Smith, M.J.;  Tüting, Thomas;  Hölzel, Michael 

Reactive neutrophil responses dependent on the receptor tyrosine kinase c-MET limit cancer immunotherapy
In: Experimental dermatology- Oxford: Wiley-Blackwell, 1992, Bd. 27.2018, 3, P137, Seite e59

Ruotsalainen, Janne;  López Ramos, Dorys Adriana;  Bonifatius, Susanne;  Sluis, Tetje;  Shridhar, Naveen;  Hinkkanen, Ari;  Riesenberg, Stefanie;  Reinhardt, Julia;  Gaffal, Evelyn;  Hölzel, Michael;  Tüting, Thomas 

Type I IFN responsiveness of melanoma is cell state dependent and can be both harnessed and suppressed to enhance oncolytic virotherapy efficacy
In: Experimental dermatology - Oxford: Wiley-Blackwell, Bd. 27.2018, 3, P187 (OP03/02), S. e82

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Artikel in Zeitschrift

Teramoto, Yukiko;  Keim, Ulrike;  Gesierich, Anja Heike;  Schuler, Gerold;  Fiedler, Eckhard;  Tüting, Thomas;  Ulrich, Claas;  Wollina, Uwe;  Hassel, Jessica C.;  Gutzmer, Ralf;  Goerdt, Sergij;  Zouboulis, Christos C.;  Leiter-Stöppke, Ulrike Martina Barbara;  Eigentler, Thomas Kurt;  Garbe, Claus 

Acral lentiginous melanoma - a skin cancer with unfavourable prognostic features : a study of the German Central Malignant Melanoma Registry (CMMR) in 2050 patients
In: British journal of dermatology - Oxford: Wiley-Blackwell, Bd. 178.2018, 2, S. 443-451

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Begutachteter Zeitschriftenartikel

Kunz, Manfred;  Löffler-Wirth, Henry;  Dannemann, Michael;  Willscher, Edith;  Doose, Gero;  Kelso, Janet;  Kottek, Tina;  Nickel, Birgit;  Hopp, Lydia;  Landsberg, Jenny;  Hoffmann, Steve;  Tüting, Thomas;  Zigrino, Paola;  Mauch, Cornelia;  Utikal, Jochen;  Ziemer, Mirjana;  Schulze, Hans-Joachim;  Hölzel, Michael;  Rösch, Alexander Oliver;  Kneitz, Susanne;  Meierjohann, Svenja;  Bosserhoff, Anja-Katrin;  Binder, Hans;  Schartl, Manfred 

RNA-seq analysis identifies different transcriptomic types and developmental trajectories of primary melanomas
In: Oncogene: including Oncogene reviews - London: Springer Nature, Bd. 37.2018, 47, S. 6136-6151

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Ottina, Eleonora;  Levy, Prisca;  Eksmond, Urszula;  Merkenschlager, Julia;  Young, George R.;  Roels, Juliette;  Stoye, Jonathan P.;  Tüting, Thomas;  Calado, Dinis P.;  Kassiotis, George 

Restoration of endogenous retrovirus infectivity impacts mouse cancer models
In: Cancer immunology research: illuminating the interplay of cancer and the immune system - Philadelphia, Pa: AACR, Bd. 6.2018, 11, S. 1292-1300

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Schiefer, Jan;  Gröne, Hermann-Josef;  Tüting, Thomas;  Chatzikyrkou, Christos;  Mertens, Peter Rene 

Von Hauteffloreszenzen zum pulmorenalen Syndrom - Eine überraschende Ursache für eine systemische Vaskulitis
In: Der Nephrologe: Zeitschrift für Nephrologie und Hypertensiologie - Berlin: Springer, Bd. 13.2018, 6, S. 411-415

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Weyden, Louise;  Arends, Mark J.;  Brenn, Thomas;  Tüting, Thomas;  Adams, David J. 

Widespread spontaneous hyperproliferation, melanosis and melanoma in Hgf-Cdk4R24C mice. Letter to the editor
In: Melanoma research - Hagerstown, Md.: Lippincott Williams & Wilkins, Bd. 28.2018, 1, S. 76-78

Publikationslink

2017

Abstrakt

Giebeler, Nives;  Schönefuß, Alexander;  Landsberg, Jennifer Caroline;  Tüting, Thomas;  Mauch, Cornelia;  Zigrino, Paola 

ADAM9 modulates melanoma development and metastasis
In: The journal of investigative dermatology - Amsterdam: Elsevier, Bd. 137.2017, Suppl. 2, Abstract 525, S. S282

Publikationslink

Ramis, Bartomeu Bibiloni;  Reinhardt, Julia;  Tüting, Thomas;  Hölzel, Michael;  Landsberg, Jennifer Caroline 

CD73 (NT5E) expression is a prognostic marker for primary melanoma patients and a potential predictive marker for anti-PD1 treatment
In: Experimental dermatology: the official journal of the European Immunodermatology Society - Oxford: Wiley-Blackwell, Bd. 26.2017, 3, P223, S. E95-E96

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Karoglan, Ante;  Quist, Sven Roy;  Gollnick, Harald;  Tueting, Thomas;  Pätzold, Bernhard 

Direct modulation of the skin microbiome as new experimental tool for skin diseases
In: Experimental dermatology: the official journal of the European Immunodermatology Society - Oxford: Wiley-Blackwell, Bd. 26.2017, 3, P067, S. E28

Publikationslink

Lührmann, Anna Fabia;  Engels, Laura;  Bergenthal, Paul;  Tüting, Thomas;  Alter, Mareike 

Fallbericht - Kombinationstherapie von Pembrolizumab und T-VEC (talimogene laherparepvec) beim malignem Melanom im inoperablen Stadium IIIC
In: Journal der Deutschen Dermatologischen Gesellschaft: JDDG : Organ der Deutschen Dermatologischen Gesellschaft (DDG) und der Österreichischen Gesellschaft für Dermatologie und Venerologie (ÖGDV) - Chichester: Blackwell, Bd. 15.2017, Suppl. 3, P32, S. 32

Publikationslink

Braun, Andreas;  Mengoni, Miriam;  Bald, Tobias;  Tüting, Thomas 

HMGB1 in phenotypic plasticity: visualizing a putative resistance mechanism
In: Experimental dermatology: the official journal of the European Immunodermatology Society - Oxford: Wiley-Blackwell, Bd. 26.2017, 3, P227, S. E97

Publikationslink

Mengoni, Miriam;  Braun, Andreas;  Shridhar, Naveen;  Gaffal, Evelyn;  Tüting, Thomas 

Interplay between aryl hydrocarbon receptor signaling and inflammatory responses in melanoma
In: Experimental dermatology: the official journal of the European Immunodermatology Society - Oxford: Wiley-Blackwell, Bd. 26.2017, 3, P226, S. E96-E97

Publikationslink

Guell, Marc;  Gabaldon, Toni;  Quist, Sven Roy;  Oudova, Veronika;  Schanze, Denny;  Tueting, Thomas;  Paetzold, Bernhard 

Long lasting effect of skin microbiome modulation induced by probiotic solution application
In: Experimental dermatology: the official journal of the European Immunodermatology Society - Oxford: Wiley-Blackwell, Bd. 26.2017, 3, P234, S. E100

Publikationslink

Karoglan, Ante;  Engels, Laura;  Alter, Mareike;  Tüting, Thomas 

Maligner Nervenscheidentumor im Rahmen einer Neurofibromatose
In: Journal der Deutschen Dermatologischen Gesellschaft: JDDG : Organ der Deutschen Dermatologischen Gesellschaft (DDG) und der Österreichischen Gesellschaft für Dermatologie und Venerologie (ÖGDV) - Chichester: Blackwell, Bd. 15.2017, Suppl. 3, P142, S. 80

Publikationslink

Kraas, Luise;  Franke, Ingolf;  Muschke, Petra;  Tüting, Thomas 

Neue Mutation bei Muir-Torre-Syndrom
In: Journal der Deutschen Dermatologischen Gesellschaft: JDDG : Organ der Deutschen Dermatologischen Gesellschaft (DDG) und der Österreichischen Gesellschaft für Dermatologie und Venerologie (ÖGDV) - Chichester: Blackwell, Bd. 15.2017, Suppl. 3, P145, S. 81

Publikationslink

Kunz, Manfred;  Dannemann, Michael;  Doose, Gero;  Kelso, Janet;  Hoffmann, Steve;  Landsberg, Jennifer Caroline;  Tüting, Thomas;  Zigrino, Paola;  Mauch, Cornelia;  Kottek, Tina;  Utikal, Jochen;  Schulze, Hans-Joachim;  Ziemer, Mirjana;  Simon, Jan C.;  Bosserhoff, Anja-Katrin;  Schartl, Manfred 

RNA-Seq analysis of benign melanocytic nevi and primary melanomas
In: Experimental dermatology: the official journal of the European Immunodermatology Society - Oxford: Wiley-Blackwell, Bd. 26.2017, 3, P200 (OP04/05), S. E86

Publikationslink

Lima, João Pereira;  Doering, Ines;  Gabaldon, Toni;  Tueting, Thomas;  Paetzold, Bernhard 

Skin surface stripping and DNA extraction for high throughput NGS analysis of the acne vulgaris-associated microbiome
In: Experimental dermatology: the official journal of the European Immunodermatology Society - Oxford: Wiley-Blackwell, Bd. 26.2017, 3, P235, S. E100

Publikationslink

Park, Simone;  Buzzai, Anthony;  Hochheiser, Katharina;  Rautela, Jai;  Hor, Jyh Liang;  Effern, Maike;  McBain, Nathan;  Whitney, Paul;  Mueller, Scott;  Huntington, Nicholas;  Tüting, Thomas;  Herold, Marco;  Hölzel, Michael;  Bedoui, Sammy;  Mackay, Laura;  Waithman, Jason;  Gebhardt, Thomas 

Skin-resident memory T cells and melanoma surveillance
In: European journal of immunology - Weinheim: Wiley VCH, Bd. 47.2017, Suppl. 2, O8, S. 8

Publikationslink

Engels, Laura;  Karoglan, Ante;  Lührmann, Anna Fabia;  Alter, Mareike;  Tüting, Thomas 

Ungewöhnliches Nebenwirkungsspektrum bei Patientin unter PD1-Therapie
In: Journal der Deutschen Dermatologischen Gesellschaft: JDDG : Organ der Deutschen Dermatologischen Gesellschaft (DDG) und der Österreichischen Gesellschaft für Dermatologie und Venerologie (ÖGDV) - Chichester: Blackwell, Bd. 15.2017, Suppl. 3, P34, S. 33

Publikationslink

Glodde, Nicole Erika;  Bald, Tobias;  Boorn-Konijnenberg, Debby;  Szczepanski, Sabrina;  Brandes, Maria;  Eickhoff, Sarah;  Shridhar, Naveen;  Hinze, Daniel;  Rogava, Meri;  Sluis, Tetje;  Ruotsalainen, Janne;  Gaffal, Evelyn;  Landsberg, Jennifer Caroline;  Ludwig, Kerstin;  Riek-Burchardt, Monika;  Müller, Andreas J.;  Janzen, Viktor;  Kastenmüller, Wolfgang;  Mazzone, Massimiliano;  Tüting, Thomas;  Hölzel, Michael 

c-MET dependent neutrophil responses limit anti-tumoral T cell expansion and immunotherapy of cancer
In: Experimental dermatology: the official journal of the European Immunodermatology Society - Oxford: Wiley-Blackwell, Bd. 26.2017, 3, P219 (OP01/03), S. E93-E94

Publikationslink

Begutachteter Zeitschriftenartikel

Layer, Julian P.;  Kronmüller, Marie T.;  Quast, Thomas Wilhelm;  Boorn-Konijnenberg, Debby;  Effern, Maike;  Hinze, Daniel;  Althoff, Kristina;  Schramm, Alexander;  Westermann, Frank;  Peifer, Martin;  Hartmann, Gunther;  Tüting, Thomas;  Kolanus, Waldemar;  Fischer, Matthias;  Schulte, Johannes;  Hölzel, Michael 

Amplification of N-Myc is associated with a T-cell-poor microenvironment in metastatic neuroblastoma restraining interferon pathway activity and chemokine expression
In: OncoImmunology - Austin, Tex: Landes Bioscience, Bd. 6.2017, 6

Publikationslink

Sektioglu, Ibrahim Murathan;  Carretero, Rafael;  Bulbuc, Nadja;  Bald, Tobias;  Tüting, Thomas;  Rudensky, Alexander Y.;  Hämmerling, Günter J. 

Basophils promote tumor rejection via chemotaxis and infiltration of CD8+ T cells
In: Cancer research - Philadelphia, Pa: AACR, Bd. 77.2017, 2, S. 291-302

Publikationslink

Giebeler, Nives;  Schönefuß, Alexander;  Landsberg, Jennifer Caroline;  Tüting, Thomas;  Mauch, Cornelia;  Zigrino, Paola 

Deletion of ADAM-9 in HGF/CDK4 mice impairs melanoma development and metastasis
In: Oncogene: including Oncogene reviews - London: Springer Nature, Bd. 36.2017, 35, S. 5058-5067

Publikationslink

Weyden, Louise;  Arends, Mark J.;  Campbell, Andrew D.;  Bald, Tobias;  Wardle-Jones, Hannah;  Griggs, Nicola;  Castillo Velasco-Herrera, Martin;  Tüting, Thomas;  Sansom, Owen J.;  Karp, Natasha A.;  Clare, Simon;  Gleeson, Diane;  Ryder, Edward;  Galli, Antonella;  Tuck, Elizabeth;  Cambridge, Emma L.;  Voet, Thierry;  Macaulay, Iain C.;  Wong, Kim;  Spiegel, Sarah;  Speak, Anneliese O.;  Adams, David J. 

Genome-wide in vivo screen identifies novel host regulators of metastatic colonization. Letter
In: Nature <London> - London [u.a.]: Nature Publ. Group, Bd. 541.2017, 7636, S. 233-236

Publikationslink

Reinhardt, Julia;  Landsberg, Jennifer Caroline;  Schmid-Burgk, Jonathan;  Ramis, Bartomeu Bibiloni;  Bald, Tobias;  Glodde, Nicole Erika;  López Ramos, Dorys Adriana;  Young, Arabella;  Ngiow, Shin Foong;  Nettersheim, Daniel;  Schorle, Hubert;  Quast, Thomas Wilhelm;  Kolanus, Waldemar;  Schadendorf, Dirk;  Long, Georgina;  Madore, Jason;  Scolyer, Richard A.;  Ribas, Antoni;  Smyth, Mark J.;  Tumeh, Paul C.;  Tüting, Thomas;  Hölzel, Michael 

MAPK Signaling and Inflammation Link Melanoma Phenotype Switching to Induction of CD73 during Immunotherapy
In: Cancer research - Philadelphia, Pa: AACR, Bd. 77.2017, 17, S. 4697-4709

Publikationslink

Engel, Christina;  Brügmann, Grethe;  Lambing, Silke;  Mühlenbeck, Larissa Helen;  Marx, Samira;  Hagen, Christian;  Horváth, Dorottya;  Goldeck, Marion;  Ludwig, Janos;  Herzner, Anna-Maria;  Drijfhout, Jan W.;  Wenzel, Daniela;  Coch, Christoph;  Tüting, Thomas;  Schlee, Martin;  Hornung, Veit;  Hartmann, Gunther;  Boorn, Jasper G. 

RIG-I resists hypoxia-induced immunosuppression and dedifferentiation
In: Cancer immunology research: illuminating the interplay of cancer and the immune system - Philadelphia, Pa: AACR, Bd. 5.2017, 6, S. 455-467

Publikationslink

Glodde, Nicole Erika;  Bald, Tobias;  Boorn-Konijnenberg, Debby;  Nakamura, Kyohei;  ODonnell, Jake S.;  Szczepanski, Sabrina;  Brandes, Maria;  Eickhoff, Sarah;  Das, Indrajit;  Shridhar, Naveen;  Hinze, Daniel;  Rogava, Meri;  Sluis, Tetje C.;  Ruotsalainen, Janne J.;  Gaffal, Evelyn;  Landsberg, Jennifer Caroline;  Ludwig, Kerstin U.;  Wilhelm, Christoph;  Riek-Burchardt, Monika;  Müller, Andreas J.;  Gebhardt, Christoffer;  Scolyer, Richard A.;  Long, Georgina;  Janzen, Viktor;  Teng, Michele W.L.;  Kastenmüller, Wolfgang;  Mazzone, Massimiliano;  Smyth, Mark J.;  Tüting, Thomas;  Hölzel, Michael 

Reactive neutrophil responses dependent on the receptor tyrosine kinase c-MET limit cancer immunotherapy
In: Immunity - [Cambridge, Mass.]: Cell Press, Bd. 47.2017, 4, S. 789-802

Publikationslink

Mescher, Melina;  Jeong, Peter;  Knapp, Sina K.;  Rübsam, Matthias;  Saynisch, Michael;  Kranen, Marina;  Landsberg, Jennifer Caroline;  Schlaak, Max Simon;  Mauch, Cornelia;  Tüting, Thomas;  Niessen, Carien M.;  Iden, Sandra 

The epidermal polarity protein Par3 is a non-cell autonomous suppressor of malignant melanoma
In: Journal of experimental medicine: JEM - New York, NY: Rockefeller Univ. Press, Bd. 214.2017, 2, S. 339-358

Publikationslink

Falletta, Paola;  Sanchez-del-Campo, Luis;  Chauhan, Jagat;  Effern, Maike;  Kenyon, Amy;  Kershaw, Christopher J.;  Siddaway, Robert;  Lisle, Richard;  Freter, Rasmus;  Daniels, Matthew J.;  Lu, Xin;  Tüting, Thomas;  Middleton, Mark;  Buffa, Francesca M.;  Willis, Anne E.;  Pavitt, Graham;  Ronai, Ze'ev A.;  Sauka-Spengler, Tatjana;  Hölzel, Michael;  Goding, Colin R. 

Translation reprogramming is an evolutionarily conserved driver of phenotypic plasticity and therapeutic resistance in melanoma
In: Genes & development: a journal devoted to the molecular analysis of gene expression in eukaryotes, prokaryotes and viruses - Stanford, Calif: HighWire Press, Bd. 31.2017, 1, S. 18-33

Publikationslink

2016

Abstrakt

Bibiloni, Ramis B.;  Reinhardt, Julia;  Tüting, Thomas;  Landsberg, Jennifer 

Histopathologische Charakterisierung und prognostische Bedeutung der Expression der Ekto-5-Nukleotidase CD73 im Melanom
In: Journal der Deutschen Dermatologischen Gesellschaft : JDDG : Organ der Deutschen Dermatologischen Gesellschaft (DDG) und der Österreichischen Gesellschaft für Dermatologie und Venerologie (ÖGDV). - Chichester : Blackwell; Bd. 14.2016, Suppl. 4, P2, S. 24

Publikationslink

Mescher, Melina;  Jeong, P.;  Rübsam, Matthias;  Kranen, M.;  Landsberg, Jennifer;  Schlaak, Max;  Mauch, Cornelia;  Tüting, Thomas;  Niessen, Carien M.;  Iden, Sandra 

Non-cell autonomous suppression of melanoma by the epidermal polarity protein Par3 through control of direct keratinocyte-melanocyte interactions
In: The journal of investigative dermatology. - Amsterdam : Elsevier; Bd. 136.2016, 9, Suppl. 2, Abs. 492, S. S244

Publikationslink

Kohlmeyer, Judith;  Landsberg, Jennifer;  Ratering, Eva-Maria;  Tüting, Thomas 

Progression of melanoma is associated with an increased expression of Ngfr - a histopathological correlation in human primary melanomas and skin metastases
In: The journal of investigative dermatology. - Amsterdam : Elsevier; Bd. 136.2016, 9, Suppl. 2, Abs. 481, S. S242

Publikationslink

Kohlmeyer, Judith;  Landsberg, Jennifer;  Ratering, Eva-Maria;  Tüting, Thomas 

The role of Ngfr expression in the progression of malignant melanoma - a histopathological correlation in human primary melanomas and skin metastases
In: Experimental dermatology : the official journal of the European Immunodermatology Society. - Oxford : Wiley-Blackwell; Bd. 25.2016, 3, P086, S. E15

Publikationslink

Begutachteter Zeitschriftenartikel

Hölzel, Michael;  Landsberg, Jennifer;  Glodde, Nicole;  Bald, Tobias;  Rogava, Meri;  Riesenberg, Stefanie;  Becker, Albert;  Jönsson, Göran;  Tüting, Thomas 

A Preclinical Model of Malignant Peripheral Nerve Sheath Tumor-like Melanoma Is Characterized by Infiltrating Mast Cells
In: Cancer Research, 2016, S. 251-263, ISSN 0008-5472, 10.1158/0008-5472.CAN-15-1090

Baar, Martina;  Coquille, Loren;  Mayer, Hannah;  Hölzel, Michael;  Rogava, Meri;  Tüting, Thomas;  Bovier, Anton 

A stochastic model for immunotherapy of cancer
In: Scientific reports - [London]: Macmillan Publishers Limited, part of Springer Nature, Bd. 6.2016, Art.-Nr. 24169, insges. 10 S.

Publikationslink

Tüting, Thomas 

Die tumorimmunologische Revolution in der Behandlung des fortgeschrittenen Melanoms. Editorial
In: Journal der Deutschen Dermatologischen Gesellschaft : JDDG. - Berlin : Wiley-Blackwell, Bd. 14.2016, 7, S. 655-656

Publikationslink

Knappe, Nathalie;  Novak, Daniel;  Weina, Kasia;  Bernhardt, Mathias;  Reith, Maike;  Larribere, Lionel;  Hölzel, Michael;  Tüting, Thomas;  Gebhardt, Christoffer;  Umansky, Viktor;  Utikal, Jochen 

Directed Dedifferentiation Using Partial Reprogramming Induces Invasive Phenotype in Melanoma Cells
In: STEM CELLS, 2016, S. 832-846, ISSN 10665099, 10.1002/stem.2284

Tüting, Thomas;  Visser, Karin E. de 

How neutrophils promote metastasis - Neutrophils may be cellular targets for cancer therapy
In: Science. - Washington, DC [u.a.] : American Association for the Advancement of Science, Bd. 352.2016, 6282, S. 145-146

Publikationslink

Hölzel, Michael;  Tüting, Thomas 

Inflammation-induced plasticity in melanoma therapy and metastasis
In: Trends in immunology. - Amsterdam [u.a.] : Elsevier Science, Bd. 37.2016, 6, S. 364-374

Publikationslink

Kilian, Marta M.;  Herwig, Martina C.;  Holz, Frank G.;  Tüting, Thomas;  Loeffler, Karin U. 

Overexpression of hepatocyte growth factor and an oncogenic CDK4 variant in mice alters corneal stroma morphology but does not lead to spontaneous ocular melanoma
In: Melanoma Research, 2016, S. 89-91, ISSN 0960-8931, 10.1097/CMR.0000000000000206

Reuten, Raphael;  Patel, Trushar R.;  McDougall, Matthew;  Rama, Nicolas;  Nikodemus, Denise;  Gibert, Benjamin;  Delcros, Jean-Guy;  Prein, Carina;  Meier, Markus;  Metzger, Stéphanie;  Zhou, Zhigang;  Kaltenberg, Jennifer;  McKee, Karen K.;  Bald, Tobias;  Tüting, Thomas;  Zigrino, Paola;  Djonov, Valentin;  Bloch, Wilhelm;  Clausen-Schaumann, Hauke;  Poschl, Ernst;  Yurchenco, Peter D.;  Ehrbar, Martin;  Mehlen, Patrick;  Stetefeld, Jörg;  Koch, Manuel 

Structural decoding of netrin-4 reveals a regulatory function towards mature basement membranes
In: Nature Communications - [London]: Nature Publishing Group UK, Bd. 7.2016, Art.-Nr. 13515, insges. 17 S.

Publikationslink

2015

Artikel in Zeitschrift

Roessler, Claudia;  Tüting, Christian;  Meleshin, Marat;  Steegborn, Clemens;  Schutkowski, Mike 

A novel continuous assay for the deacylase sirtuin 5 and other deacetylases
In: Journal of medicinal chemistry - Washington, DC: ACS, Bd. 58.2015, 18, S. 7217-7223

Publikationslink

Begutachteter Zeitschriftenartikel

Lu, K.-H.;  Tounsi, A.;  Shridhar, N.;  Küblbeck, G.;  Klevenz, A.;  Prokosch, S.;  Bald, T.;  Tüting, T.;  Arnold, B. 

Dickkopf-3 contributes to the regulation of anti-tumor immune responses by mesenchymal stem cells
In: Frontiers in Immunology, Vol. 6, 2015, Issue DEC, 10.3389/fimmu.2015.00645

Glodde, N.;  Jakobs, M.;  Bald, T.;  Tüting, T.;  Gaffal, E. 

Differential role of cannabinoids in the pathogenesis of skin cancer
In: Life Sciences, Vol. 138, 2015, S. 35-40, 10.1016/j.lfs.2015.04.003

Kunz, M.;  Konig, I.R.;  Schillert, A.;  Kruppa, J.;  Ziegler, A.;  Grallert, H.;  Muller-Nurasyid, M.;  Lieb, W.;  Franke, A.;  Ranki, A.;  Panelius, J.;  Koskenmies, S.;  Hasan, T.;  Kere, J.;  Ronn, A.-C.;  Simon, J.C.;  Schmidt, E.;  Wenzel, J.;  Tuting, T.;  Landsberg, J.;  Zeller, T.;  Blankenberg, S.;  Glaser, R.;  Patsinakidis, N.;  Kuhn, A.;  Ibrahim, S.M. 

Genome-wide association study identifies new susceptibility loci for cutaneous lupus erythematosus
In: Experimental Dermatology, Vol. 24, 2015, Issue 7, S. 510-515, 10.1111/exd.12708

Riesenberg, S.;  Groetchen, A.;  Siddaway, R.;  Bald, T.;  Reinhardt, J.;  Smorra, D.;  Kohlmeyer, J.;  Renn, M.;  Phung, B.;  Aymans, P.;  Schmidt, T.;  Hornung, V.;  Davidson, I.;  Goding, C.R.;  Jönsson, G.;  Landsberg, J.;  Tüting, T.;  Hölzel, M. 

MITF and c-Jun antagonism interconnects melanoma dedifferentiation with pro-inflammatory cytokine responsiveness and myeloid cell recruitment
In: Nature Communications, Vol. 6, 2015, 10.1038/ncomms9755

Bald, Tobias;  Landsberg, Jennifer;  Jansen, Philipp;  Gaffal, Evelyn;  Tüting, Thomas 

Phorbol ester-induced neutrophilic inflammatory responses selectively promote metastatic spread of melanoma in a TLR4-dependent manner
In: OncoImmunology, 2015, S. e1078964, ISSN 2162-402X, 10.1080/2162402X.2015.1078964

Meister, M.;  Tounsi, A.;  Gaffal, E.;  Bald, T.;  Papatriantafyllou, M.;  Ludwig, J.;  Pougialis, G.;  Bestvater, F.;  Klotz, L.;  Moldenhauer, G.;  Tüting, T.;  Hämmerling, G.J.;  Arnold, B.;  Oelert, T. 

Self-Antigen Presentation by Keratinocytes in the Inflamed Adult Skin Modulates T-Cell Auto-Reactivity
In: Journal of Investigative Dermatology, Vol. 135, 2015, Issue 8, S. 1996-2004, 10.1038/jid.2015.130

2014

Begutachteter Zeitschriftenartikel

Schmitz, A.-L.;  Schrage, R.;  Gaffal, E.;  Charpentier, T.H.;  Wiest, J.;  Hiltensperger, G.;  Morschel, J.;  Hennen, S.;  Häußler, D.;  Horn, V.;  Wenzel, D.;  Grundmann, M.;  Büllesbach, K.M.;  Schröder, R.;  Brewitz, H.H.;  Schmidt, J.;  Gomeza, J.;  Galés, C.;  Fleischmann, B.K.;  Tüting, T.;  Imhof, D.;  Tietze, D.;  Gütschow, M.;  Holzgrabe, U.;  Sondek, J.;  Harden, T.K.;  Mohr, K.;  Kostenis, E. 

A cell-permeable inhibitor to trap Gαq proteins in the empty pocket conformation
In: Chemistry and Biology, Vol. 21, 2014, Issue 7, S. 890-902, 10.1016/j.chembiol.2014.06.003

Sistigu, A.;  Yamazaki, T.;  Vacchelli, E.;  Chaba, K.;  Enot, D.P.;  Adam, J.;  Vitale, I.;  Goubar, A.;  Baracco, E.E.;  Remédios, C.;  Fend, L.;  Hannani, D.;  Aymeric, L.;  Ma, Y.;  Niso-Santano, M.;  Kepp, O.;  Schultze, J.L.;  Tüting, T.;  Belardelli, F.;  Bracci, L.;  La Sorsa, V.;  Ziccheddu, G.;  Sestili, P.;  Urbani, F.;  Delorenzi, M.;  Lacroix-Triki, M.;  Quidville, V.;  Conforti, R.;  Spano, J.-P.;  Pusztai, L.;  Poirier-Colame, V.;  Delaloge, S.;  Penault-Llorca, F.;  Ladoire, S.;  Arnould, L.;  Cyrta, J.;  Dessoliers, M.-C.;  Eggermont, A.;  Bianchi, M.E.;  Pittet, M.;  Engblom, C.;  Pfirschke, C.;  Préville, X.;  Uzè, G.;  Schreiber, R.D.;  Chow, M.T.;  Smyth, M.J.;  Proietti, E.;  André, F.;  Kroemer, G.;  Zitvogel, L. 

Cancer cell-autonomous contribution of type I interferon signaling to the efficacy of chemotherapy
In: Nature medicine, Vol. 20, 2014, Issue 11, S. 1301-1309, 10.1038/nm.3708

Gaffal, E.;  Glodde, N.;  Jakobs, M.;  Bald, T.;  Tüting, T. 

Cannabinoid 1 receptors in keratinocytes attenuate fluorescein isothiocyanate-induced mouse atopic-like dermatitis
In: Experimental Dermatology, Vol. 23, 2014, Issue 6, S. 401-406, 10.1111/exd.12414

Bald, T.;  Landsberg, J.;  Lopez-Ramos, D.;  Renn, M.;  Glodde, N.;  Jansen, P.;  Gaffal, E.;  Steitz, J.;  Tolba, R.;  Kalinke, U.;  Limmer, A.;  Jönsson, G.;  Hölzel, M.;  Tüting, T. 

Immune cell-poor melanomas benefit from PD-1 blockade after targeted type I IFN activation
In: Cancer Discovery, Vol. 4, 2014, Issue 6, S. 674-687, 10.1158/2159-8290.CD-13-0458

Bald, T.;  Quast, T.;  Landsberg, J.;  Rogava, M.;  Glodde, N.;  Lopez-Ramos, D.;  Kohlmeyer, J.;  Riesenberg, S.;  Van Den Boorn-Konijnenberg, D.;  Hömig-Hölzel, C.;  Reuten, R.;  Schadow, B.;  Weighardt, H.;  Wenzel, D.;  Helfrich, I.;  Schadendorf, D.;  Bloch, W.;  Bianchi, M.E.;  Lugassy, C.;  Barnhill, R.L.;  Koch, M.;  Fleischmann, B.K.;  Förster, I.;  Kastenmüller, W.;  Kolanus, W.;  Hölzel, M.;  Gaffal, E.;  Tüting, T. 

Ultraviolet-radiation-induced inflammation promotes angiotropism and metastasis in melanoma
In: Nature, Vol. 507, 2014, Issue 7490, S. 109-113, 10.1038/nature13111

Gaffal, E.;  Jakobs, M.;  Glodde, N.;  Schröder, R.;  Kostenis, E.;  Tüting, T. 

β-arrestin 2 inhibits proinflammatory chemokine production and attenuates contact allergic inflammation in the skin
In: Journal of Investigative Dermatology, Vol. 134, 2014, Issue 8, S. 2131-2137, 10.1038/jid.2014.117

2013

Begutachteter Zeitschriftenartikel

Gaffal, E.;  Cron, M.;  Glodde, N.;  Tüting, T. 

Anti-inflammatory activity of topical THC in DNFB-mediated mouse allergic contact dermatitis independent of CB1 and CB2 receptors
In: Allergy: European Journal of Allergy and Clinical Immunology, Vol. 68, 2013, Issue 8, S. 994-1000, 10.1111/all.12183

Steitz, J.;  Tüting, T. 

Biolistic DNA vaccination against melanoma
In: Methods in Molecular Biology, Vol. 940, 2013, S. 317-337, 10.1007/978-1-62703-110-3_24

Gaffal, E.;  Cron, M.;  Glodde, N.;  Bald, T.;  Kuner, R.;  Zimmer, A.;  Lutz, B.;  Tüting, T. 

Cannabinoid 1 receptors in keratinocytes modulate proinflammatory chemokine secretion and attenuate contact allergic inflammation
In: Journal of Immunology, Vol. 190, 2013, Issue 10, S. 4929-4936, 10.4049/jimmunol.1201777

Zahn, S.;  Graef, M.;  Barchet, W.;  Bieber, T.;  Tüting, T.;  Wenzel, J. 

Nitrosative stress: A hallmark of the junctional inflammation in cutaneous lupus erythematosus
In: Clinical and Experimental Dermatology, Vol. 38, 2013, Issue 1, S. 96-97, 10.1111/j.1365-2230.2012.04472.x

Gehrke, N.;  Mertens, C.;  Zillinger, T.;  Wenzel, J.;  Bald, T.;  Zahn, S.;  Tüting, T.;  Hartmann, G.;  Barchet, W. 

Oxidative damage of dna confers resistance to cytosolic nuclease trex1 degradation and potentiates STING-dependent immune sensing
In: Immunity, Vol. 39, 2013, Issue 3, S. 482-495, 10.1016/j.immuni.2013.08.004

Hölzel, M.;  Bovier, A.;  Tüting, T. 

Plasticity of tumour and immune cells: A source of heterogeneity and a cause for therapy resistance?
In: Nature Reviews Cancer, Vol. 13, 2013, Issue 5, S. 365-376, 10.1038/nrc3498

Tüting, T. 

T cell immunotherapy for melanoma from bedside to bench to barn and back: How conceptual advances in experimental mouse models can be translated into clinical benefit for patients
In: Pigment Cell and Melanoma Research, Vol. 26, 2013, Issue 4, S. 441-456, 10.1111/pcmr.12111

2012

Begutachteter Zeitschriftenartikel

Hornung, T.;  Ko, A.;  Tüting, T.;  Bieber, T.;  Wenzel, J. 

Efficacy of low-dose methotrexate in the treatment of dermatomyositis skin lesions
In: Clinical and Experimental Dermatology, Vol. 37, 2012, Issue 2, S. 139-142, 10.1111/j.1365-2230.2011.04188.x

Landsberg, J.;  Kohlmeyer, J.;  Renn, M.;  Bald, T.;  Rogava, M.;  Cron, M.;  Fatho, M.;  Lennerz, V.;  Wölfel, T.;  Hölzel, M.;  Tüting, T. 

Melanomas resist T-cell therapy through inflammation-induced reversible dedifferentiation
In: Nature, Vol. 490, 2012, Issue 7420, S. 412-416, 10.1038/nature11538

2011

Begutachteter Zeitschriftenartikel

Hangalapura, B.N.;  Oosterhoff, D.;  Gupta, T.;  de Groot, J.;  Wijnands, P.G.J.T.B.;  van Beusechem, V.W.;  den Haan, J.;  TÜting, T.;  van den Eertwegh, A.J.M.;  Curiel, D.T.;  Scheper, R.J.;  de Gruijl, T.D. 

Delivery route, MyD88 signaling and cross-priming events determine the anti-tumor efficacy of an adenovirus based melanoma vaccine
In: Vaccine, Vol. 29, 2011, Issue 12, S. 2313-2321, 10.1016/j.vaccine.2011.01.022

Freutel, S.;  Gaffal, E.;  Zahn, S.;  Bieber, T.;  Tüting, T.;  Wenzel, J. 

Enhanced CCR5+/CCR3+ T helper cell ratio in patients with active cutaneous lupus erythematosus
In: Lupus, Vol. 20, 2011, Issue 12, S. 1300-1304, 10.1177/0961203311409267

Zahn, S.;  Barchet, W.;  Rehkämper, C.;  Hornung, T.;  Bieber, T.;  Tüting, T.;  Wenzel, J. 

Enhanced skin expression of melanoma differentiation-associated gene 5 (MDA5) in dermatomyositis and related autoimmune diseases
In: Journal of the American Academy of Dermatology, Vol. 64, 2011, Issue 5, S. 988-989, 10.1016/j.jaad.2010.08.004

Zahn, S.;  Rehkämper, C.;  Kümmerer, B.M.;  Ferring-Schmidt, S.;  Bieber, T.;  Tüting, T.;  Wenzel, J. 

Evidence for a pathophysiological role of keratinocyte-derived type III interferon (IFNλ) in cutaneous lupus erythematosus
In: Journal of Investigative Dermatology, Vol. 131, 2011, Issue 1, S. 133-140, 10.1038/jid.2010.244

Koch, P.;  Breuer, P.;  Peitz, M.;  Jungverdorben, J.;  Kesavan, J.;  Poppe, D.;  Doerr, J.;  Ladewig, J.;  Mertens, J.;  Tüting, T.;  Hoffmann, P.;  Klockgether, T.;  Evert, B.O.;  Wüllner, U.;  Brüstle, O. 

Excitation-induced ataxin-3 aggregation in neurons from patients with Machado-Joseph disease
In: Nature, Vol. 480, 2011, Issue 7378, S. 543-546, 10.1038/nature10671

Kübler, K.;  tho Pesch, C.;  Gehrke, N.;  Riemann, S.;  Daßler, J.;  Coch, C.;  Landsberg, J.;  Wimmenauer, V.;  Pölcher, M.;  Rudlowski, C.;  Tüting, T.;  Kuhn, W.;  Hartmann, G.;  Barchet, W. 

Immunogenic cell death of human ovarian cancer cells induced by cytosolic poly(I:C) leads to myeloid cell maturation and activates NK cells
In: European Journal of Immunology, Vol. 41, 2011, Issue 10, S. 3028-3039, 10.1002/eji.201141555

Zahn, S.;  Rehkamper, C.;  Ferring-Schmitt, S.;  Bieber, T.;  Tuting, T.;  Wenzel, J. 

Interferon-α stimulates TRAIL expression in human keratinocytes and peripheral blood mononuclear cells: Implications for the pathogenesis of cutaneous lupus erythematosus
In: British Journal of Dermatology, Vol. 165, 2011, Issue 5, S. 1118-1123, 10.1111/j.1365-2133.2011.10479.x

Gaffal, E.;  Gaffal, J.;  Bald, T.;  Sporleder, A.;  Kohlmeyer, J.;  Tüting, T. 

Neonatal UVB exposure accelerates melanoma growth and enhances distant metastases in Hgf-Cdk4 R24C C57BL/6 mice
In: International Journal of Cancer, Vol. 129, 2011, Issue 2, S. 285-294, 10.1002/ijc.25913

Hangalapura, B.N.;  Oosterhoff, D.;  De Groot, J.;  Boon, L.;  Tuếing, T.;  Van Den Eertwegh, A.J.;  Gerritsen, W.R.;  Van Beusechem, V.W.;  Pereboev, A.;  Curiel, D.T.;  Scheper, R.J.;  De Gruijl, T.D. 

Potent antitumor immunity generated by a CD40-targeted adenoviral vaccine
In: Cancer Research, Vol. 71, 2011, Issue 17, S. 5827-5837, 10.1158/0008-5472.CAN-11-0804

2010

Begutachteter Zeitschriftenartikel

Landsberg, J.;  Gaffal, E.;  Cron, M.;  Kohlmeyer, J.;  Renn, M.;  Tüting, T. 

Autochthonous primary and metastatic melanomas in Hgf-Cdk4R24C mice evade T-cell-mediated immune surveillance
In: Pigment Cell and Melanoma Research, Vol. 23, 2010, Issue 5, S. 649-660, 10.1111/j.1755-148X.2010.00744.x

Stabenow, D.;  Frings, M.;  Trück, C.;  Gärtner, K.;  Förster, I.;  Kurts, C.;  Tüting, T.;  Odentha, M.;  Dienes, H.-P.;  Cederbrant, K.;  Protzer, U.;  Knolle, P.A. 

Bioluminescence imaging allows measuring CD8 T cell function in the liver
In: Hepatology, Vol. 51, 2010, Issue 4, S. 1430-1437, 10.1002/hep.23575

Backer, R.;  Schwandt, T.;  Greuter, M.;  Oosting, M.;  Jüngerkes, F.;  Tüting, T.;  Boon, L.;  O'Toole, T.;  Kraal, G.;  Limmer, A.;  Den Haan, J.M.M. 

Effective collaboration between marginal metallophilic macrophages and CD8+ dendritic cells in the generation of cytotoxic T cells
In: Proceedings of the National Academy of Sciences of the United States of America, Vol. 107, 2010, Issue 1, S. 216-221, 10.1073/pnas.0909541107

Hendrickson, R.C.;  Cicinnati, V.R.;  Albers, A.;  Dworacki, G.;  Gambotto, A.;  Pagliano, O.;  Tüting, T.;  Mayordomo, J.I.;  Visus, C.;  Appella, E.;  Shabanowitz, J.;  Hunt, D.F.;  Deleo, A.B. 

Identification of a 17β-hydroxysteroid dehydrogenase type 12 pseudogene as the source of a highly restricted BALB/c Meth A tumor rejection peptide
In: Cancer Immunology, Immunotherapy, Vol. 59, 2010, Issue 1, S. 113-124, 10.1007/s00262-009-0730-7

Eberle, J.;  Spangler, B.;  Becker, J.C.;  Heinemann, S.H.;  Klein, C.A.;  Kunz, M.;  Kuphal, S.;  Langer, P.;  Mauch, C.;  Meierjohann, S.;  Paschen, A.;  Schadendorf, D.;  Schartl, M.;  Schittek, B.;  Schönherr, R.;  Tüting, T.;  Zigrino, P.;  Bosserhoff, A.K. 

Multicentre study on standardisation of melanoma cell culture - An initiative of the German Melanoma Research Network
In: Pigment Cell and Melanoma Research, Vol. 23, 2010, Issue 2, S. 296-298, 10.1111/j.1755-148X.2010.00684.x

Tüting, T. 

Of swords and ploughshares: Immunosurveillance and inflammation in melanoma
In: Pigment Cell and Melanoma Research, Vol. 23, 2010, Issue 6, S. 727-728, 10.1111/j.1755-148X.2010.00754.x

Wenzel, J.;  Zahn, S.;  Tüting, T. 

Pathogenesis of cutaneous lupus erythematosus: Common and different features in distinct subsets
In: Lupus, Vol. 19, 2010, Issue 9, S. 1020-1028, 10.1177/0961203310370046

Petrosino, S.;  Cristino, L.;  Karsak, M.;  Gaffal, E.;  Ueda, N.;  Tüting, T.;  Bisogno, T.;  De Filippis, D.;  D'Amico, A.;  Saturnino, C.;  Orlando, P.;  Zimmer, A.;  Iuvone, T.;  Di Marzo, V. 

Protective role of palmitoylethanolamide in contact allergic dermatitis
In: Allergy: European Journal of Allergy and Clinical Immunology, Vol. 65, 2010, Issue 6, S. 698-711, 10.1111/j.1398-9995.2009.02254.x

Osen, W.;  Soltek, S.;  Song, M.;  Leuchs, B.;  Steitz, J.;  Tüting, T.T.;  Eichmüller, S.B.E.;  Nguyen, X.;  Schadendorf, D.;  Paschen, A. 

Screening of human tumor antigens for CD4+ T cell epitopes by combination of HLA-transgenic mice, recombinant adenovirus and antigen peptide libraries
In: PLoS ONE, Vol. 5, 2010, Issue 11, 10.1371/journal.pone.0014137

2009

Begutachteter Zeitschriftenartikel

Ney, J.T.;  Schmidt, T.;  Kurts, C.;  Zhou, Q.;  Eckert, D.;  Felsher, D.W.;  Schorle, H.;  Knolle, P.;  Tüting, T.;  Barchet, W.;  Büttner, R.;  Limmer, A.;  Gütgemann, I. 

Autochthonous liver tumors induce systemic T cell tolerance associated with T cell receptor down-modulation
In: Hepatology, Vol. 49, 2009, Issue 2, S. 471-481, 10.1002/hep.22652

Kohlmeyer, J.;  Cron, M.;  Landsberg, J.;  Bald, T.;  Renn, M.;  Mikus, S.;  Bondong, S.;  Wikasari, D.;  Gaffal, E.;  Hartmann, G.;  Tüting, T. 

Complete regression of advanced primary and metastatic mouse melanomas following combination chemoimmunotherapy
In: Cancer Research, Vol. 69, 2009, Issue 15, S. 6265-6274, 10.1158/0008-5472.CAN-09-0579

Cicinnati, V.R.;  Kang, J.;  Hou, J.;  Lindemann, M.;  Koop, K.;  Tüting, T.;  Gerken, G.;  Beckebaum, S. 

Interferon-α differentially affects homeostasis of human plasmacytoid and myeloid dendritic cells
In: Journal of Interferon and Cytokine Research, Vol. 29, 2009, Issue 3, S. 145-159, 10.1089/jir.2008.0011

Wiechert, A.;  Reinhard, G.;  Tüting, T.;  Uerlich, M.;  Bieber, T.;  Wenzel, J. 

Multiple skin cancers in a patient treated with hydroxyurea [Multiple kutane Neoplasien nach Therapie mit Hydroxyurea]
In: Hautarzt, Vol. 60, 2009, Issue 8, S. 651-654, 10.1007/s00105-008-1673-1

Tormo, D.;  Checiſska, A.;  Alonso-Curbelo, D.;  Pérez-Guijarro, E.;  Cañón, E.;  Riveiro-Falkenbach, E.;  Calvo, T.G.;  Larribere, L.;  Megías, D.;  Mulero, F.;  Piris, M.A.;  Dash, R.;  Barral, P.M.;  Rodríguez-Peralto, J.L.;  Ortiz-Romero, P.;  Tüting, T.;  Fisher, P.B.;  Soengas, M.S. 

Targeted Activation of Innate Immunity for Therapeutic Induction of Autophagy and Apoptosis in Melanoma Cells
In: Cancer Cell, Vol. 16, 2009, Issue 2, S. 103-114, 10.1016/j.ccr.2009.07.004

Wenzel, J.;  Zahn, S.;  Bieber, T.;  Tüting, T. 

Type I interferon-associated cytotoxic inflammation in cutaneous lupus erythematosus
In: Archives of Dermatological Research, Vol. 301, 2009, Issue 1, S. 83-86, 10.1007/s00403-008-0892-8

2008

Begutachteter Zeitschriftenartikel

Poeck, H.;  Besch, R.;  Maihoefer, C.;  Renn, M.;  Tormo, D.;  Morskaya, S.S.;  Kirschnek, S.;  Gaffal, E.;  Landsberg, J.;  Hellmuth, J.;  Schmidt, A.;  Anz, D.;  Bscheider, M.;  Schwerd, T.;  Berking, C.;  Bourquin, C.;  Kalinke, U.;  Kremmer, E.;  Kato, H.;  Akira, S.;  Meyers, R.;  Häcker, G.;  Neuenhahn, M.;  Busch, D.;  Ruland, J.;  Rothenfusser, S.;  Prinz, M.;  Hornung, V.;  Endres, S.;  Tüting, T.;  Hartmann, G. 

5′-triphosphate-siRNA: Turning gene silencing and Rig-I activation against melanoma
In: Nature Medicine, Vol. 14, 2008, Issue 11, S. 1256-1263, 10.1038/nm.1887

Wenzel, J.;  Lucas, S.;  Zahn, S.;  Mikus, S.;  Metze, D.;  Ständer, S.;  von Stebut, E.;  Hillen, U.;  Bieber, T.;  Tüting, T. 

CXCR3 <-> ligand-mediated skin inflammation in cutaneous lichenoid graft-versus-host disease
In: Journal of the American Academy of Dermatology, Vol. 58, 2008, Issue 3, S. 437-442, 10.1016/j.jaad.2007.10.647

Wenzel, J.;  Peters, B.;  Zahn, S.;  Birth, M.;  Hofmann, K.;  Küsters, D.;  Tomiuk, S.;  Baron, J.M.;  Merk, H.F.;  Mauch, C.;  Krieg, T.;  Bieber, T.;  Tüting, T.;  Bosio, A. 

Gene expression profiling of lichen planus reflects CXCL9+-mediated inflammation and distinguishes this disease from atopic dermatitis and psoriasis
In: Journal of Investigative Dermatology, Vol. 128, 2008, Issue 1, S. 67-78, 10.1038/sj.jid.5700945

Singh, B.;  Ezziddin, S.;  Palmedo, H.;  Reinhardt, M.;  Strunk, H.;  Tüting, T.;  Biersack, H.-J.;  Ahmadzadehfar, H. 

Preoperative 18F-FDG-PET/CT imaging and sentinel node biopsy in the detection of regional lymph node metastases in malignant melanoma
In: Melanoma Research, Vol. 18, 2008, Issue 5, S. 346-352, 10.1097/CMR.0b013e32830b363b

Wiechert, A.;  Tüting, T.;  Bieber, T.;  Haidl, G.;  Wenzel, J. 

Subacute cutaneous lupus erythematosus in a leuprorelin-treated patient with prostate carcinoma
In: British Journal of Dermatology, Vol. 159, 2008, Issue 1, S. 231-233, 10.1111/j.1365-2133.2008.08587.x

Hamprecht, A.;  Tüting, T.;  Bieber, T.;  Wenzel, J. 

Successful treatment of recalcitrant malar rash in a patient with cutaneous lupus erythematosus with efalizumab
In: Clinical and Experimental Dermatology, Vol. 33, 2008, Issue 3, S. 347-348, 10.1111/j.1365-2230.2007.02648.x

Booken, N.;  Gratchev, A.;  Utikal, J.;  Weiß, C.;  Yu, X.;  Qadoumi, M.;  Schmuth, M.;  Sepp, N.;  Nashan, D.;  Rass, K.;  Tüting, T.;  Assaf, C.;  Dippel, E.;  Stadler, R.;  Klemke, C.-D.;  Goerdt, S. 

Sézary syndrome is a unique cutaneous T-cell lymphoma as identified by an expanded gene signature including diagnostic marker molecules CDO1 and DNM3
In: Leukemia, Vol. 22, 2008, Issue 2, S. 393-399, 10.1038/sj.leu.2405044

Betz, R.C.;  König, K.;  Flaquer, A.;  Redler, S.;  Eigelshoven, S.;  Kortüm, A.-K.;  Hanneken, S.;  Hillmer, A.;  Tüting, T.;  Lambert, J.;  De Weert, J.;  Kruse, R.;  Lutz, G.;  Blaumeiser, B.;  Nöthen, M.M. 

The R620W polymorphism in PTPN22 confers general susceptibility for the development of alopecia areata
In: British Journal of Dermatology, Vol. 158, 2008, Issue 2, S. 389-391, 10.1111/j.1365-2133.2007.08312.x

Wenzel, J.;  Tormo, D.;  Tüting, T. 

Toll-like receptor-agonists in the treatment of skin cancer: History, current developments and future prospects
In: Handbook of Experimental Pharmacology, Vol. 183, 2008, S. 201-220, 10.1007/978-3-540-72167-3-10

Wenzel, J.;  Tomiuk, S.;  Zahn, S.;  Küsters, D.;  Vahsen, A.;  Wiechert, A.;  Mikus, S.;  Birth, M.;  Scheler, M.;  Von Bubnoff, D.;  Baron, J.M.;  Merk, H.F.;  Mauch, C.;  Krieg, T.;  Bieber, T.;  Bosio, A.;  Hofmann, K.;  Tüting, T.;  Peters, B. 

Transcriptional profiling identifies an interferon-associated host immune response in invasive squamous cell carcinoma of the skin
In: International Journal of Cancer, Vol. 123, 2008, Issue 11, S. 2605-2615, 10.1002/ijc.23799

Buchbeitrag

Wenzel, J.;  Tüting, T. 

An IFN-associated cytotoxic cellular immune response against viral, self-, or tumor antigens is a common pathogenetic feature in "interface dermatitis"
In: Journal of Investigative Dermatology, Vol. 128, 2008, Issue 10, S. 2392-2402, 10.1038/jid.2008.96

Tüting, T. 

New ways in melanoma therapy [Neue wege in der melanomtherapie]
In: JDDG - Journal of the German Society of Dermatology, Vol. 6, 2008, Issue 10, S. 815-816, 10.1111/j.1610-0387.2008.06879.x

2007

Begutachteter Zeitschriftenartikel

Distelmaier, M.;  Gaffal, E.;  Wenzel, J.;  Rabini, S.;  Tüting, T. 

Application study Bepanthol Body Lotion Plus for atopic skin [Anwendungsbeobachtung Bepanthol Körperlotion Plus bei atopischer Haut]
In: Kosmetische Medizin, Vol. 28, 2007, Issue 4, S. 182-185

Karsak, M.;  Gaffal, E.;  Date, R.;  Wang-Eckhardt, L.;  Rehnelt, J.;  Petrosino, S.;  Starowicz, K.;  Steuder, R.;  Schlicker, E.;  Cravatt, B.;  Mechoulam, R.;  Buettner, R.;  Werner, S.;  Di Marzo, V.;  Tüting, T.;  Zimmer, A. 

Attenuation of allergic contact dermatitis through the endocannabinoid system
In: Science, Vol. 316, 2007, Issue 5830, S. 1494-1497, 10.1126/science.1142265

Wenzel, J.;  Proelss, J.;  Wiechert, A.;  Zahn, S.;  Bieber, T.;  Tüting, T. 

CXCR3-mediated recruitment of cytotoxic lymphocytes in lupus erythematosus profundus
In: Journal of the American Academy of Dermatology, Vol. 56, 2007, Issue 4, S. 648-650, 10.1016/j.jaad.2006.08.014

Gaffal, E.;  Schweichel, D.;  Tormo, D.;  Steitz, J.;  Lenz, J.;  Basner-Tschakarjan, E.;  Limmer, A.;  Tüting, T. 

Comparative evaluation of CD8+CTL responses following gene gun immunization targeting the skin with intracutaneous injection of antigen-transduced dendritic cells
In: European Journal of Cell Biology, Vol. 86, 2007, Issue 11-12, S. 817-826, 10.1016/j.ejcb.2006.07.002

Wenzel, J.;  Wiechert, A.;  Merkel, C.;  Bieber, T.;  Tüting, T. 

IP10/CXCL10 - CXCR3 interaction: A potential self-recruiting mechanism for cytotoxic lymphocytes in lichen sclerosus et atrophicus
In: Acta Dermato-Venereologica, Vol. 87, 2007, Issue 2, S. 112-117, 10.2340/00015555-0194

Wenzel, J.;  Tüting, T. 

Identification of type I interferon-associated inflammation in the pathogenesis of cutaneous lupus erythematosus opens up options for novel therapeutic approaches
In: Experimental Dermatology, Vol. 16, 2007, Issue 5, S. 454-463, 10.1111/j.1600-0625.2007.00556.x

Scheler, M.;  Wenzel, J.;  Tüting, T.;  Takikawa, O.;  Bieber, T.;  Von Bubnoff, D. 

Indoleamine 2,3-dioxygenase (IDO): The antagonist of type I interferon-driven skin inflammation?
In: American Journal of Pathology, Vol. 171, 2007, Issue 6, S. 1936-1943, 10.2353/ajpath.2007.070281

Betz, R.C.;  Pforr, J.;  Flaquer, A.;  Redler, S.;  Hanneken, S.;  Eigelshoven, S.;  Kortüm, A.-K.;  Tüting, T.;  Lambert, J.;  De Weert, J.;  Hillmer, A.M.;  Schmael, C.;  Wienker, T.F.;  Kruse, R.;  Lutz, G.;  Blaumeiser, B.;  Nöthen, M.M. 

Loss-of-function mutations in the filaggrin gene and alopecia areata: Strong risk factor for a severe course of disease in patients comorbid for atopic disease
In: Journal of Investigative Dermatology, Vol. 127, 2007, Issue 11, S. 2539-2543, 10.1038/sj.jid.5700915

Ten Freyhaus, K.;  Kaiser, H.-W.;  Proelss, J.;  Tüting, T.;  Bieber, T.;  Wenzel, J. 

Successful treatment of bullous congenital ichthyosiform erythroderma with erythromycin [2]
In: Dermatology, Vol. 215, 2007, Issue 1, S. 81-83, 10.1159/000102043

Wenzel, J.;  Zahn, S.;  Mikus, S.;  Wiechert, A.;  Bieber, T.;  Tüting, T. 

The expression pattern of interferon-inducible proteins reflects the characteristic histological distribution of infiltrating immune cells in different cutaneous lupus erythematosus subsets
In: British Journal of Dermatology, Vol. 157, 2007, Issue 4, S. 752-757, 10.1111/j.1365-2133.2007.08137.x

Sokoſowska-Wojdyſo, M.;  Speuser, P.;  Tüting, T. 

The neoplastic T cells' culture in cutaneous T cell lymphomas - Never ending challenge [Hodowla nowotworowych komórek T w chÅ¿oniakach pierwotnie skórnych z komórek T - Nieustaja̧ce wyzwanie]
In: Przeglad Dermatologiczny, Vol. 94, 2007, Issue 4, S. 495-499

Buchbeitrag

Tüting, T. 

Preclinical development of melanoma vaccines with toll-like receptor ligands in a novel genetic mouse model
In: Arzneimittel-Forschung/Drug Research, Vol. 57, 2007, Issue 1, S. 67

2006

Begutachteter Zeitschriftenartikel

Utikal, J.;  Poenitz, N.;  Gratchev, A.;  Klemke, C.-D.;  Nashan, D.;  Tüting, T.;  Goerdt, S. 

Additional Her 2/neu gene copies in patients with Sézary syndrome
In: Leukemia Research, Vol. 30, 2006, Issue 6, S. 755-760, 10.1016/j.leukres.2005.10.012

Basner-Tschakarjan, E.;  Gaffal, E.;  O'Keeffe, M.;  Tormo, D.;  Limmer, A.;  Wagner, H.;  Hochrein, H.;  Tüting, T. 

Adenovirus efficiently transduces plasmacytoid dendritic cells resulting in TLR9-dependent maturation and IFN-α production
In: Journal of Gene Medicine, Vol. 8, 2006, Issue 11, S. 1300-1306, 10.1002/jgm.964

Steitz, J.;  Tormo, D.;  Schweichel, D.;  Tüting, T. 

Comparison of recombinant adenovirus and synthetic peptide for DC-based melanoma vaccination
In: Cancer Gene Therapy, Vol. 13, 2006, Issue 3, S. 318-325, 10.1038/sj.cgt.7700894

Reinhardt, M.J.;  Joe, A.Y.;  Jaeger, U.;  Huber, A.;  Matthies, A.;  Bucerius, J.;  Roedel, R.;  Strunk, H.;  Bieber, T.;  Biersack, H.-J.;  Tüting, T. 

Diagnostic performance of whole body dual modality 18F-FDG PET/CT imaging for N- and M-staging of malignant melanoma: Experience with 250 consecutive patients
In: Journal of Clinical Oncology, Vol. 24, 2006, Issue 7, S. 1178-1187, 10.1200/JCO.2005.03.5634

Steitz, J.;  Britten, C.M.;  Wölfel, T.;  Tüting, T. 

Effective induction of anti-melanoma immunity following genetic vaccination with synthetic mRNA coding for the fusion protein EGFP.TRP2
In: Cancer Immunology, Immunotherapy, Vol. 55, 2006, Issue 3, S. 246-253, 10.1007/s00262-005-0042-5

Schweichel, D.;  Steitz, J.;  Tormo, D.;  Gaffal, E.;  Ferrer, A.;  Büchs, S.;  Speuser, P.;  Limmer, A.;  Tüting, T. 

Evaluation of DNA vaccination with recombinant adenoviruses using bioluminescence imaging of antigen expression: Impact of application routes and delivery with dendritic cells
In: Journal of Gene Medicine, Vol. 8, 2006, Issue 10, S. 1243-1250, 10.1002/jgm.952

Steitz, J.;  Büchs, S.;  Tormo, D.;  Ferrer, A.;  Wenzel, J.;  Huber, C.;  Wölfel, T.;  Barbacid, M.;  Malumbres, M.;  Tüting, T. 

Evaluation of genetic melanoma vaccines in cdk4-mutant mice provides evidence for immunological tolerance against autochthonous melanomas in the skin
In: International Journal of Cancer, Vol. 118, 2006, Issue 2, S. 373-380, 10.1002/ijc.21349

Huber, A.;  Tüting, T.;  Bauer, R.;  Bieber, T.;  Wenzel, J. 

Methotrexate treatment in cutaneous lupus erythematosus: Subcutaneous application is as effective as intravenous administration [16]
In: British Journal of Dermatology, Vol. 155, 2006, Issue 4, S. 861-862, 10.1111/j.1365-2133.2006.07431.x

Chromik, J.;  Schnürer, E.;  Georg Meyer, R.;  Wehler, T.;  Tüting, T.;  Wölfel, T.;  Huber, C.;  Herr, W. 

Proteasome-inhibited dendritic cells demonstrate improved presentation of exogenous synthetic and natural HLA-class I peptide epitopes
In: Journal of Immunological Methods, Vol. 308, 2006, Issue 1-2, S. 77-89, 10.1016/j.jim.2005.09.021

Tormo, D.;  Ferrer, A.;  Gaffal, E.;  Wenzel, J.;  Basner-Tschakarjan, E.;  Steitz, J.;  Heukamp, L.C.;  Gütgemann, I.;  Buettner, R.;  Malumbres, M.;  Barbacid, M.;  Merlino, G.;  Tüting, T. 

Rapid growth of invasive metastatic melanoma in carcinogen-treated hepatocyte growth factor/scatter factor-transgenic mice carrying an oncogenic CDK4 mutation
In: American Journal of Pathology, Vol. 169, 2006, Issue 2, S. 665-672, 10.2353/ajpath.2006.060017

Wingender, G.;  Garbi, N.;  Schumak, B.;  Jüngerkes, F.;  Endl, E.;  von Bubnoff, D.;  Steitz, J.;  Striegler, J.;  Moldenhauer, G.;  Tüting, T.;  Heit, A.;  Huster, K.M.;  Takikawa, O.;  Akira, S.;  Busch, D.H.;  Wagner, H.;  Hämmerling, G.J.;  Knolle, P.A.;  Limmer, A. 

Systemic application of CpG-rich DNA suppresses adaptive T cell immunity via induction of IDO
In: European Journal of Immunology, Vol. 36, 2006, Issue 1, S. 12-20, 10.1002/eji.200535602

Tormo, D.;  Ferrer, A.;  Bosch, P.;  Gaffal, E.;  Basner-Tschakarjan, E.;  Wenzel, J.;  Tüting, T. 

Therapeutic efficacy of antigen-specific vaccination and toll-like receptor stimulation against established transplanted and autochthonous melanoma in mice
In: Cancer Research, Vol. 66, 2006, Issue 10, S. 5427-5435, 10.1158/0008-5472.CAN-06-0399

Huber, A.;  Gaffal, E.;  Bieber, T.;  Tüting, T.;  Wenzel, J. 

Treatment of recalcitrant dermatomyositis with efalizumab [3]
In: Acta Dermato-Venereologica, Vol. 86, 2006, Issue 3, S. 254-255, 10.2340/00015555-0058

Wenzel, J.;  Scheler, M.;  Proelss, J.;  Bieber, T.;  Tüting, T. 

Type I interferon-associated cytotoxic inflammation in lichen planus
In: Journal of Cutaneous Pathology, Vol. 33, 2006, Issue 10, S. 672-678, 10.1111/j.1600-0560.2006.00527.x

Wenzel, J.;  Schmidt, R.;  Proelss, J.;  Zahn, S.;  Bieber, T.;  Tüting, T. 

Type I interferon-associated skin recruitment of CXCR3+ lymphocytes in dermatomyositis
In: Clinical and Experimental Dermatology, Vol. 31, 2006, Issue 4, S. 576-582, 10.1111/j.1365-2230.2006.02150.x

2005

Begutachteter Zeitschriftenartikel

Sokolowska-Wojdylo, M.;  Wenzel, J.;  Gaffal, E.;  Steitz, J.;  Roszkiewicz, J.;  Bieber, T.;  Tüting, T. 

Absence of CD26 expression on skin-homing CLA+ CD4+ T lymphocytes in peripheral blood is a highly sensitive marker for early diagnosis and therapeutic monitoring of patients with Sézary syndrome
In: Clinical and Experimental Dermatology, Vol. 30, 2005, Issue 6, S. 702-706, 10.1111/j.1365-2230.2005.01904.x

Brück, J.;  Steitz, J.;  Strand, D.;  Tüting, T. 

Altered intracellular sorting signals do not influence the efficacy of genetic melanoma vaccines incorporating helper determinants in mice
In: Journal of Gene Medicine, Vol. 7, 2005, Issue 5, S. 613-620, 10.1002/jgm.702

Sokolowska-Wojdylo, M.;  Wenzel, J.;  Gaffal, E.;  Lenz, J.;  Speuser, P.;  Erdmann, S.;  Abuzahra, F.;  Bowman, E.;  Roszkiewicz, J.;  Bieber, T.;  Tüting, T. 

Circulating clonal CLA+ and CD4+ T cells in Sézary syndrome express the skin-homing chemokine receptors CCR4 and CCR10 as well as the lymph node-homing chemokine receptor CCR7
In: British Journal of Dermatology, Vol. 152, 2005, Issue 2, S. 258-264, 10.1111/j.1365-2133.2004.06325.x

Wenzel, J.;  Brähler, S.;  Bauer, R.;  Bieber, T.;  Tüting, T. 

Efficacy and safety of methotrexate in recalcitrant cutaneous lupus erythematosus: Results of a retrospective study in 43 patients
In: British Journal of Dermatology, Vol. 153, 2005, Issue 1, S. 157-162, 10.1111/j.1365-2133.2005.06552.x

Wenzel, J.;  Wörenkämper, E.;  Freutel, S.;  Henze, S.;  Haller, O.;  Bieber, T.;  Tüting, T. 

Enhanced type I interferon signalling promotes Th1-biased inflammation in cutaneous lupus erythematosus
In: Journal of Pathology, Vol. 205, 2005, Issue 4, S. 435-442, 10.1002/path.1721

Steitz, J.;  Bruck, J.;  Lenz, J.;  Buchs, S.;  Tüting, T. 

Erratum: Breaking tolerance - Another piece added to the vitiligo puzzle (Journal of Investigative Dermatology (2005) 124 (xiii-xv))
In: Journal of Investigative Dermatology, Vol. 124, 2005, Issue 5, S. 1092, 10.1111/j.0022-202X.2005.23751.x

Wenzel, J.;  Scheler, M.;  Bieber, T.;  Tüting, T.;  Caproni, M.;  Torchia, D.;  Fabbri, P. 

Evidence for a role of type I interferons in the pathogenesis of dermatomyositis [15] (multiple letters)
In: British Journal of Dermatology, Vol. 153, 2005, Issue 2, S. 462-464, 10.1111/j.1365-2133.2005.06786.x

Cicinnati, V.R.;  Dworacki, G.;  Albers, A.;  Beckebaum, S.;  Tüting, T.;  Kaczmarek, E.;  DeLeo, A.B. 

Impact of p53-based immunization on primary chemically-induced tumors
In: International Journal of Cancer, Vol. 113, 2005, Issue 6, S. 961-970, 10.1002/ijc.20686

Steitz, J.;  Brück, J.;  Lenz, J.;  Büchs, S.;  Tüting, T. 

Peripheral CD8+ T cell tolerance against melanocytic self-antigens in the skin is regulated in two steps by CD4+ T cells and local inflammation: Implications for the pathophysiology of vitiligo
In: Journal of Investigative Dermatology, Vol. 124, 2005, Issue 1, S. 144-150, 10.1111/j.0022-202X.2004.23538.x

Wenzel, J.;  Henze, S.;  Wörenkämper, E.;  Basner-Tschakarjan, E.;  Sokolowska-Wojdylo, M.;  Steitz, J.;  Bieber, T.;  Tüting, T. 

Role of the chemokine receptor CCR4 and its ligand thymus- and activation-regulated chemokine/CCL17 for lymphocyte recruitment in cutaneous lupus erythematosus
In: Journal of Investigative Dermatology, Vol. 124, 2005, Issue 6, S. 1241-1248, 10.1111/j.0022-202X.2005.23755.x

Wenzel, J.;  Uerlich, M.;  Wörrenkämper, E.;  Freutel, S.;  Bieber, T.;  Tüting, T. 

Scarring skin lesions of discoid lupus erythematosus are characterized by high numbers of skin-homing cytotoxic lymphocytes associated with strong expression of the type I interferon-induced protein MxA
In: British Journal of Dermatology, Vol. 153, 2005, Issue 5, S. 1011-1015, 10.1111/j.1365-2133.2005.06784.x

Wenzel, J.;  Bauer, R.;  Bieber, T.;  Tüting, T. 

Successful rituximab treatment of severe Pemphigus vulgaris resistant to multiple immunosuppressants [8]
In: Acta Dermato-Venereologica, Vol. 85, 2005, Issue 2, S. 185-186, 10.1080/00015550410024111

Wenzel, J.;  Henze, S.;  Brähler, S.;  Bieber, T.;  Tüting, T. 

The expression of human leukocyte antigen-DR and CD25 on circulating T cells in cutaneous lupus erythematosus and correlation with disease activity
In: Experimental Dermatology, Vol. 14, 2005, Issue 6, S. 454-459, 10.1111/j.0906-6705.2005.00301.x

Wenzel, J.;  Gütgemann, I.;  Distelmaier, M.;  Uerlich, M.;  Mikus, S.;  Bieber, T.;  Tüting, T. 

The role of cytotoxic skin-homing CD8+ lymphocytes in cutaneous cytotoxic T-cell lymphoma and pityriasis lichenoides
In: Journal of the American Academy of Dermatology, Vol. 53, 2005, Issue 3, S. 422-427, 10.1016/j.jaad.2005.05.042

Wenzel, J.;  Philipp-Dormston, W.;  Bieber, T.;  Tüting, T. 

Topical treatment of bullous pemphigoid with tacrolimus. Case report with brief literature review [Topische therapie des bullösen pemphigoids mit tacrolimus. Ein fallbericht mit kurzer übersicht die literatur]
In: JDDG - Journal of the German Society of Dermatology, Vol. 3, 2005, Issue 3, S. 207-210

Wenzel, J.;  Bekisch, B.;  Uerlich, M.;  Haller, O.;  Bieber, T.;  Tüting, T. 

Type I interferon-associated recruitment of cytotoxic lymphocytes: A common mechanism in regressive melanocytic lesions
In: American Journal of Clinical Pathology, Vol. 124, 2005, Issue 1, S. 37-48, 10.1309/4EJ9-KL7C-GDEN-VVLE

2004

Begutachteter Zeitschriftenartikel

Tuettenberg, A.;  Jonuleit, H.;  Tüting, T.;  Brück, J.;  Biermann, V.;  Kochanek, S.;  Knop, J.;  Enk, A.H. 

Early Adenoviral Gene Expression Mediates Immunosuppression by Transduced Dendritic Cell (DC): Implications for Immunotherapy Using Genetically Modified DC
In: Journal of Immunology, Vol. 172, 2004, Issue 3, S. 1524-1530

Steitz, J.;  Wenzel, J.;  Gaffal, E.;  Tüting, T. 

Initiation and regulation of CD8+T cells recognizing melanocytic antigens in the epidermis: Implications for the pathophysiology of vitiligo
In: European Journal of Cell Biology, Vol. 83, 2004, Issue 11-12, S. 797-803, 10.1078/0171-9335-00423

Wenzel, J.;  Montag, S.;  Wilsmann-Theis, D.;  Gaffal, E.;  Bieber, T.;  Tüting, T. 

Successful treatment of recalcitrant Wegener's granulomatosis of the skin with tacrolimus (Prograf™) [1]
In: British Journal of Dermatology, Vol. 151, 2004, Issue 4, S. 927-928, 10.1111/j.1365-2133.2004.06187.x

De Palma, R.;  Marigo, I.;  Del Galdo, F.;  De Santo, C.;  Serafini, P.;  Cingarlini, S.;  Tüting, T.;  Lenz, J.;  Basso, G.;  Milan, G.;  Zanovello, P.;  Bronte, V. 

Therapeutic effectiveness of recombinant cancer vaccines is associated with a prevalent T-cell receptor α usage by melanoma-specific CD8+ T lymphocytes
In: Cancer Research, Vol. 64, 2004, Issue 21, S. 8068-8076, 10.1158/0008-5472.CAN-04-0067

2003

Begutachteter Zeitschriftenartikel

Wenzel, J.;  Tüting, T.;  Bieber, T. 

Cutaneous lesions in lupus erythematosus [Kutane manifestationen des lupus erythematodes]
In: Deutsche Medizinische Wochenschrift, Vol. 128, 2003, Issue 31-32, S. 1655-1658, 10.1055/s-2003-41095

Tuettenberg, A.;  Jonuleit, H.;  Tüting, T.;  Brück, J.;  Knop, J.;  Enk, A.H. 

Priming of T cells with Ad-transduced DC followed by expansion with peptide-pulsed DC significantly enhances the induction of tumor-specific CD8+ T cells: Implications for an efficient vaccination strategy
In: Gene Therapy, Vol. 10, 2003, Issue 3, S. 243-250, 10.1038/sj.gt.3301880

Wenzel, J.;  Bieber, T.;  Uerlich, M.;  Tüting, T. 

Systemic treatment of cutaneous lupus erythematosus [Systemische therapie des kutanen lupus erythematodes]
In: JDDG - Journal of the German Society of Dermatology, Vol. 1, 2003, Issue 9, S. 694-704, 10.1046/j.1610-0387.2003.03024.x

Ross, R.;  Sudowe, S.;  Beisner, J.;  Ross, X.-L.;  Ludwig-Portugall, I.;  Steitz, J.;  Tüting, T.;  Knop, J.;  Reske-Kunz, A.B. 

Transcriptional targeting of dendritic cells for gene therapy using the promoter of the cytoskeletal protein fascin
In: Gene Therapy, Vol. 10, 2003, Issue 12, S. 1035-1040, 10.1038/sj.gt.3301968

2002

Begutachteter Zeitschriftenartikel

Sudowe, S.;  Montermann, E.;  Steitz, J.;  Tüting, T.;  Knop, J.;  Reske-Kunz, A.B. 

Efficacy of recombinant adenovirus as vector for allergen gene therapy in a mouse model of type I allergy
In: Gene Therapy, Vol. 9, 2002, Issue 2, S. 147-156, 10.1038/sj/gt/3301625

Steitz, J.;  Brück, J.;  Gambotto, A.;  Knop, J.;  Tüting, T. 

Genetic immunization with a melanocytic self-antigen linked to foreign helper sequences breaks tolerance and induces autoimmunity and tumor immunity
In: Gene Therapy, Vol. 9, 2002, Issue 3, S. 208-213, 10.1038/sj/gt/3301634

Müller, G.;  Müller, A.;  Tüting, T.;  Steinbrink, K.;  Saloga, J.;  Szalma, C.;  Knop, J.;  Enk, A.H. 

Interleukin-10-treated dendritic cells modulate immune responses of naive and sensitized T cells In vivo
In: Journal of Investigative Dermatology, Vol. 119, 2002, Issue 4, S. 836-841, 10.1046/j.1523-1747.2002.00496.x

Tüting, T.;  Reinhard, G. 

Tumor immunity and autoimmunity: Lessons for the development of modern melanome vaccines learned in murine models [Tumorimmunabwehr und autoimmunität: Erkenntnisse für die entwicklung moderner melanomvakzinen aus tierexperimentellen studien]
In: H+G Zeitschrift fur Hautkrankheiten, Vol. 77, 2002, Issue 11, S. 553-558, 10.1046/j.1439-0353.2002.02604.x

2001

Begutachteter Zeitschriftenartikel

Jonuleit, H.;  Giesecke-Tuettenberg, A.;  Tüting, T.;  Thurner-Schuler, B.;  Stuge, T.B.;  Paragnik, L.;  Kandemir, A.;  Lee, P.P.;  Schuler, G.;  Knop, J.;  Enk, A.H. 

A comparison of two types of dendritic cell as adjuvants for the induction of melanoma-specific T-cell responses in humans following intranodal injection
In: International Journal of Cancer, Vol. 93, 2001, Issue 2, S. 243-251, 10.1002/ijc.1323

Steitz, J.;  Brück, J.;  Knop, J.;  Tüting, T. 

Adenovirus-transduced dendritic cells stimulate cellular immunity to melanoma via a CD4+ T cell-dependent mechanism
In: Gene Therapy, Vol. 8, 2001, Issue 16, S. 1255-1263, 10.1038/sj.gt.3301521

Steitz, J.;  Brück, J.;  Lenz, J.;  Knop, J.;  Tüting, T. 

Depletion of CD25+ CD4+ T cells and treatment with tyrosinase-related protein 2-transduced dendritic cells enhance the interferon α-induced, CD8+ T-cell-dependent immune defense of B16 melanoma
In: Cancer Research, Vol. 61, 2001, Issue 24, S. 8643-8646

2000

Begutachteter Zeitschriftenartikel

Jonuleit, H.;  Tüting, T.;  Steitz, J.;  Brück, J.;  Giesecke, A.;  Steinbrink, K.;  Knop, J.;  Enk, A.H. 

Efficient transduction of mature CD83+ dendritic cells using recombinant adenovirus suppressed T cell stimulatory capacity
In: Gene Therapy, Vol. 7, 2000, Issue 3, S. 249-254

Steitz, J.;  Brück, J.;  Steinbrink, K.;  Alexander, E.;  Knop, J.;  Tüting, T. 

Genetic immunization of mice with human tyrosinase-related protein 2: Implications for the immunotherapy of melanoma
In: International Journal of Cancer, Vol. 86, 2000, Issue 1, S. 89-94, 10.1002/(SICI)1097-0215(20000401)86:1<89::AID-IJC14>3.0.CO;2-I

Hiroishi, K.;  Tüting, T.;  Lotze, M.T. 

IFN-α-expressing tumor cells enhance generation and promote survival of tumor-specific CTLs
In: Journal of Immunology, Vol. 164, 2000, Issue 2, S. 567-572

Gambotto, A.;  Dworacki, G.;  Cicinnati, V.;  Kenniston, T.;  Steitz, J.;  Tüting, T.;  Robbins, P.D.;  DeLeo, A.B. 

Immunogenicity of enhanced green fluorescent protein (EGFP) in BALB/c mice: Identification of an H2-Kd-restricted CTL epitope
In: Gene Therapy, Vol. 7, 2000, Issue 23, S. 2036-2040, 10.1038/sj.gt.3301335

Steinbrink, K.;  Paragnik, L.;  Jonuleit, H.;  Tüting, T.;  Knop, J.;  Enk, A.H. 

Induction of dendritic cell maturation and modulation of dendritic cell-induced immune responses by prostaglandins
In: Archives of Dermatological Research, Vol. 292, 2000, Issue 9, S. 437-445

1999

Begutachteter Zeitschriftenartikel

Tüting, T.;  Gambotto, A.;  Robbins, P.D.;  Storkus, W.J.;  DeLeo, A.B. 

Co-delivery of T helper 1-biasing cytokine genes enhances the efficacy of gene gun immunization of mice: Studies with the model tumor antigen β-galactosidase and the BALB/c Meth A p53 tumor-specific antigen
In: Gene Therapy, Vol. 6, 1999, Issue 4, S. 629-636, 10.1038/sj.gt.3300859

Tüting, T.;  Steitz, J.;  Brück, J.;  Gambotto, A.;  Steinbrink, K.;  DeLeo, A.B.;  Robbins, P.;  Knop, J.;  Enk, A.H. 

Dendritic Cell-based Genetic Immunization in Mice with a Recombinant Adenovirus Encoding Murine TRP2 Induces Effective Anti-melanoma Immunity
In: Journal of Gene Medicine, Vol. 1, 1999, Issue 6, S. 400-406

Wilson, C.C.;  Olson, W.C.;  Tuting, T.;  Rinaldo, C.R.;  Lotze, M.T.;  Storkus, W.J. 

HIV-1-specific, CTL responses primed in vitro by blood-derived dendritic cells and Th1-biasing cytokines
In: Journal of Immunology, Vol. 162, 1999, Issue 5, S. 3070-3078

Gambotto, A.;  Tüting, T.;  McVey, D.L.;  Kovesdi, I.;  Tahara, H.;  Lotze, M.T.;  Robbins, P.D. 

Induction of antitumor immunity by direct intratumoral injection of a recombinant adenovirus vector expressing interleukin-12
In: Cancer Gene Therapy, Vol. 6, 1999, Issue 1, S. 45-53

Tüting, T.;  Gambotto, A.;  DeLeo, A.;  Lotze, M.T.;  Robbins, P.D.;  Storkus, W.J. 

Induction of tumor antigen-specific immunity using plasmid DNA immunization in mice
In: Cancer Gene Therapy, Vol. 6, 1999, Issue 1, S. 73-80

Hiroishi, K.;  Tüting, T.;  Tahara, H.;  Lotze, M.T. 

Interferon-alpha gene therapy in combination with CD80 transduction reduces tumorigenicity and growth of established tumor in poorly immunogenic tumor models
In: Gene Therapy, Vol. 6, 1999, Issue 12, S. 1988-1994, 10.1038/sj.gt.3301034

Tüting, T. 

The immunology of cutaneous DNA immunization
In: Current Opinion in Molecular Therapeutics, Vol. 1, 1999, Issue 2, S. 216-225

1998

Begutachteter Zeitschriftenartikel

Tüting, T.;  Wilson, C.C.;  Martin, D.M.;  Kasamon, Y.L.;  Rowles, J.;  Ma, D.I.;  Slingluff Jr., C.L.;  Wagner, S.N.;  Van Der Bruggen, P.;  Baar, J.;  Lotze, M.T.;  Storkus, W.J. 

Autologous human monocyte-derived dendritic cells genetically modified to express melanoma antigens elicit primary cytotoxic T cell responses in vitro: Enhancement by cotransfection of genes encoding the Th1-biasing cytokines IL-12 and IFN-α
In: Journal of Immunology, Vol. 160, 1998, Issue 3, S. 1139-1147

Tüting, T.;  Storkus, W.J.;  Falo Jr., L.D. 

DNA immunization targeting the skin: Molecular control of adaptive immunity
In: Journal of Investigative Dermatology, Vol. 111, 1998, Issue 2, S. 183-188, 10.1046/j.1523-1747.1998.00261.x

Tüting, T.;  Wilson, C.C.;  Martin, D.M.;  Baar, J.;  DeLeo, A.;  Lotze, M.T.;  Storkus, W.J. 

DNA vaccines targeting dendritic cells for the immunotherapy of cancer
In: Advances in Experimental Medicine and Biology, Vol. 451, 1998, S. 295-304

1997

Begutachteter Zeitschriftenartikel

Tüting, T.;  Storkus, W.J.;  Lotze, M.T. 

Gene-based strategies for the immunotherapy of cancer
In: Journal of Molecular Medicine, Vol. 75, 1997, Issue 7, S. 478-491, 10.1007/s001090050133

Tüting, T.;  DeLeo, A.B.;  Lotze, M.T.;  Storkus, W.J. 

Genetically modified bone marrow-derived dendritic cells expressing tumor-associated viral or 'self' antigens induce antitumor immunity in vivo
In: European Journal of Immunology, Vol. 27, 1997, Issue 10, S. 2702-2707, 10.1002/eji.1830271033

Tüting, T.;  Gambotto, A.;  Baar, J.;  Davis, I.D.;  Storkus, W.J.;  Zavodny, P.J.;  Narula, S.;  Tahara, H.;  Robbins, P.D.;  Lotze, M.T. 

Interferon-α gene therapy for cancer: Retroviral transduction of fibroblasts and particle-mediated transfection of tumor cells are both effective strategies for gene delivery in murine tumor models
In: Gene Therapy, Vol. 4, 1997, Issue 10, S. 1053-1060

Buchbeitrag

Tüting, T.;  Zorina, T.;  Ma, D.I.;  Wilson, C.C.;  De Cesare, C.M.;  De Leo, A.B.;  Lotze, M.T.;  Storkus, W.J. 

Development of dendritic cell-based genetic vaccines for cancer
In: Advances in Experimental Medicine and Biology, Vol. 417, 1997, S. 511-518

1996

Begutachteter Zeitschriftenartikel

Tuting, T.;  Bork, K. 

Primary plasmacytoma of the skin
In: Journal of the American Academy of Dermatology, Vol. 34, 1996, Issue 2 II, S. 386-390

1995

Begutachteter Zeitschriftenartikel

Hoh, R.;  Meyer-Rogge, D.;  Tuting, T.;  Sorhage, B. 

Familial benign chronic pemphigus (Hailey-Hailey-disease) - Therapy with dermabrasion [PEMPHIGUS CHRONICUS BENIGNUS FAMILIARIS (MORBUS-HAILEY-HAILEY). THERAPIE MITTELS DERMABRASION]
In: Aktuelle Dermatologie, Vol. 21, 1995, Issue 12, S. 403-405

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