Prof. Dr.- Ing. Reichl

Hochschullehrer/-in

Prof. Dr.-Ing. Udo Reichl

Lehrstuhl Bioprozesstechnik
Fakultät für Verfahrens- und Systemtechnik (FVST)
Universitätsplatz 2, 39106 Magdeburg, G25-112
Projekte

Aktuelle Projekte

Abgeschlossene Projekte

Publikationen

2021

Begutachteter Zeitschriftenartikel

Rand, Ulfert;  Kupke, Sascha Young;  Shkarlet, Hanna;  Hein, Marc Dominique;  Hirsch, Tatjana;  Marichal-Gallardo, Pável Alejandro;  Cicin-Sain, Luka;  Reichl, Udo;  Bruder, Dunja 

Antiviral activity of influenza A virus defective interfering particles against SARS-CoV-2 replication in vitro through stimulation of innate immunity
In: Cells: open access journal - Basel: MDPI, 2012, Bd. 10 (2021), 7, insges. 14 S.

Marichal-Gallardo, Pavel;  Börner, Kathleen;  Pieler, Michael M.;  Sonntag-Buck, Vera;  Obr, Martin;  Bejarano, David;  Wolff, Michael W.;  Kräusslich, Hans-Georg;  Reichl, Udo;  Grimm, Dirk 

Associated viral gene transfer vectors by membrane-based steric exclusion chromatography
In: Human gene therapy - New York, NY: Liebert, 2021, insgesamt 16 Seiten

Hein, Marc D.;  Arora, Prerna;  Marichal-Gallardo, Pável Alejandro;  Winkler, Michael;  Genzel, Yvonne;  Pöhlmann, Stefan;  Schughart, Klaus;  Kupke, Sascha Y.;  Reichl, Udo 

Cell culture-based production and in vivo characterization of purely clonal defective interfering influenza virus particles
In: BMC biology - Berlin: Springer, Bd. 19 (2021)

Pralow, Alexander;  Hoffmann, Marcus;  Nguyen-Khuong, Terry;  Pioch, Markus;  Hennig, René;  Genzel, Yvonne;  Rapp, Erdmann;  Reichl, Udo 

Comprehensive Nglycosylation analysis of the influenza A virus proteins HA and NA from adherent and suspension MDCK cells
In: The FEBS journal/ Vereinigung der Europäischen Biochemischen Gesellschaften - Oxford [u.a.]: Wiley-Blackwell . - 2021

Biemann, Ronald;  Buß, Enrico;  Benndorf, Dirk;  Lehmann, Theresa;  Schallert, Kay;  Püttker, Sebastian;  Reichl, Udo;  Isermann, Berend;  Schneider, Jochen;  Saake, Gunter;  Heyer, Robert Steven 

Fecal metaproteomics reveals reduced gut inflammation and changed microbial metabolism following lifestyle-induced weight loss
In: Biomolecules: open access journal - Basel: MDPI, 2011, Vol.11.2021, 5, 726, insgesamt 13 Seiten

Reichl, Udo;  Seidel-Morgenstern, Andreas;  Sundmacher, Kai;  Tsotsas, Evangelos;  Wachem, Berend 

Forschungsarbeiten am Institut für Verfahrenstechnik der OttovonGuerickeUniversität Magdeburg
In: Chemie - Ingenieur - Technik: CIT - Weinheim: Wiley-VCH Verl., Bd. 93 (2021), 3, S. 345-352

Wu, Yixiao;  Bissinger, Thomas;  Genzel, Yvonne;  Liu, Xuping;  Reichl, Udo;  Tan, Wen-Song 

High cell density perfusion process for high yield of influenza A virus production using MDCK suspension cells
In: Applied microbiology and biotechnology - Berlin: Springer, Bd. 105 (2021), 4, S. 1421-1434

Meinusch, Nicole;  Kramer, Susanne;  Körner, Oliver;  Wiese, Jürgen;  Seick, Ingolf;  Beblek, Anita;  Berges, Regine;  Illenberger, Bernhard;  Illenberger, Marco;  Uebbing, Jennifer;  Wolf, Maximilian;  Saake, Gunter;  Benndorf, Dirk;  Reichl, Udo;  Heyer, Robert Steven 

Integrated cycles for urban biomass as a strategy to promote a co2-neutral society - a feasibility study
In: Sustainability - Basel: MDPI, Bd. 13 (2021), 17, insges. 22 S.

Mahour, Reza;  Marichal-Gallardo, Pavel A.;  Rexer, Thomas;  Reichl, Udo 

Multienzyme cascades for the in vitro synthesis of guanosine diphosphate Lfucose
In: ChemCatChem - Weinheim: WILEY-VCH Verlag, Bd. 13 (2021), insges. 11 S.

Hein, Marc D.;  Kollmus, Heike;  Marichal-Gallardo, Pavel;  Püttker, Sebastian;  Benndorf, Dirk;  Genzel, Yvonne;  Schughart, Klaus;  Kupke, Sascha Y.;  Reichl, Udo 

OP7, a novel influenza A virus defective interfering particle - production, purification, and animal experiments demonstrating antiviral potential
In: Applied microbiology and biotechnology - Berlin: Springer, Bd. 105 (2021), 1, S. 129-146

Offersgaard, Anna;  Duarte Hernandez, Carlos Rene;  Pihl, Anne Finne;  Costa, Rui;  Venkatesan, Nandine Prabhakar;  Lin, Xiangliang;  Pham, Long Van;  Feng, Shan;  Fahnøe, Ulrik;  Scheel, Troels Kasper Høyer;  Ramirez, Santseharay;  Reichl, Udo;  Bukh, Jens;  Genzel, Yvonne;  Gottwein, Judith Margarete 

SARS-CoV-2 production in a scalable high cell density bioreactor
In: Vaccines: open access journal - Basel: MDPI, Bd. 9 (2021)

Pralow, Alexander;  Nikolay, Alexander;  Leon, Arnaud;  Genzel, Yvonne;  Rapp, Erdmann;  Reichl, Udo 

Site-specific N-glycosylation analysis of animal cell culture-derived Zika virus proteins
In: Scientific reports - [London]: Macmillan Publishers Limited, part of Springer Nature, Bd. 11 (2021)

Bissinger, Thomas;  Wu, Yixiao;  Marichal-Gallardo, Pavel;  Riedel, Dietmar;  Liu, Xuping;  Genzel, Yvonne;  Tan, Wen-Song;  Reichl, Udo 

Towards integrated production of an influenza A vaccine candidate with MDCK suspension cells
In: Biotechnology & bioengineering - New York, NY [u.a.]: Wiley . - 2021, S. 1-18

Pech, Sabine;  Rehberg, Markus;  Janke, Robert;  Benndorf, Dirk;  Genzel, Yvonne;  Muth, Thilo;  Sickmann, Albert;  Rapp, Erdmann;  Reichl, Udo 

Tracking changes in adaptation to suspension growth for MDCK cells: cell growth correlates with levels of metabolites, enzymes and proteins
In: Applied microbiology and biotechnology - Berlin: Springer, Bd. 105 (2021), S. 1861-1874

Wissenschaftliche Monographie

Rapp, Erdmann [HerausgeberIn];  Reichl, Udo [HerausgeberIn] 

Advances in glycobiotechnology
In: Cham: Springer, 2021, viii, 461 Seiten, Illustrationen, Diagramme, 24 cm - (Advances in biochemical engineering/biotechnology; 175)

2020

Artikel in Zeitschrift

Rexer, Thomas F. T.;  Wenzel, Lisa;  Hoffmann, Marcus;  Tischlik, Sebastian;  Bergmann, Christin;  Grote, Valerian;  Boecker, Simon Matthias;  Bettenbrock, Katja;  Schildbach, Anna;  Kottler, Robert;  Mahour, Reza;  Rapp, Erdmann;  Pietzsch, Markus;  Reichl, Udo 

Synthesis of lipid-linked oligosaccharides by a compartmentalized multi-enzyme cascade for the in vitro N-glycosylation of peptides
In: Journal of biotechnology - Amsterdam [u.a.]: Elsevier Science, 1984, Bd. 322 (2020), S. 54-65

Begutachteter Zeitschriftenartikel

Ramos, João R.;  Rath, Alexander G.;  Genzel, Yvonne;  Sandig, Volker;  Reichl, Udo 

A dynamic model linking cell growth to intracellular metabolism and extracellular byproduct accumulation
In: Biotechnology & bioengineering - New York, NY [u.a.]: Wiley . - 2020, insges. 21 S.

Coronel, Juliana;  Gränicher, Gwendal;  Sandig, Volker;  Noll, Thomas;  Genzel, Yvonne;  Reichl, Udo 

Application of an nnclined settler for cell culture-based influenza A virus production in perfusion mode
In: Frontiers in Bioengineering and Biotechnology - Lausanne: Frontiers Media, Volume 8 (2020), article 672, insgesmat 13 Seiten

Heyer, Robert Steven;  Klang, Johanna;  Hellwig, Patrick;  Schallert, Kay;  Kress, Philipp;  Hülsemann, Benedikt;  Theuerl, Susanne;  Reichl, Udo;  Benndorf, Dirk 

Impact of feeding and stirring regimes on the internal stratification of microbial communities in the fermenter of anaerobic digestion plants
In: Bioresource technology - Amsterdam [u.a.]: Elsevier Science, 314(2020), Artikel-Nummer 123679, 1 Online-Ressource, Illustrationen, Diagramme

Gränicher, Gwendal;  Coronel, Juliana;  Trampler, Felix;  Jordan, Ingo;  Genzel, Yvonne;  Reichl, Udo 

Performance of an acoustic settler versus a hollow fiberbased ATF technology for influenza virus production in perfusion
In: Applied microbiology and biotechnology - Berlin: Springer, Bd. 104.2020, S. 4877-4888

Gränicher, Gwendal;  Tapia, Felipe;  Behrendt, Ilona;  Jordan, Ingo;  Genzel, Yvonne;  Reichl, Udo 

Production of Modified Vaccinia Ankara virus by intensified cell cultures - a comparison of platform technologies for viral vector production
In: Biotechnology journal: BTJ ; systems & synthetic biology, nanobiotech, medicine - Weinheim: Wiley-VCH, 2020, Artikelnr. 2000024, insgesamt 10 Seiten

Kupke, Sascha Young;  Ly, Lam-Ha;  Börno, Stefan Thomas;  Ruff, Alexander;  Timmermann, Bernd;  Vingron, Martin;  Haas, Stefan;  Reichl, Udo 

Single-cell analysis uncovers a vast diversity in intracellular viral defective interfering RNA content affecting the large cell-to-cell heterogeneity in influenza A virus replication
In: Viruses - Basel: MDPI, 12 (2020,1), Artikelnummer 71, 19 Seiten

Nikolay, Alexander;  Grooth, Joris;  Genzel, Yvonne;  Wood, Jeffery A.;  Reichl, Udo 

Virus harvesting in perfusion culture - choosing the right type of hollow fiber membrane
In: Biotechnology & bioengineering - New York, NY [u.a.]: Wiley, 2020, insgesamt 13 Seiten

Buchbeitrag

Nikolay, Alexander;  Bissinger, Thomas;  Gränicher, Gwendal;  Wu, Yixiao;  Genzel, Yvonne;  Reichl, Udo 

Perfusion control for high cell density cultivation and viral vaccine production
In: Animal Cell Biotechnology: Methods and Protocols - New York, NY: Springer US; Pörtner, Ralf . - 2020, S. 141-168

Dissertation

Hoffmann, Marcus;  Reichl, Udo [AkademischeR BetreuerIn];  Rapp, Erdmann [AkademischeR BetreuerIn] 

In-depth mass spectrometry-based glycoproteomics - advances in sample preparation, measurement and data-analysis of glycoproteins
In: Magdeburg, 2020, XI, 141 Seiten, Illustrationen, Diagramme, 30 cm ; [Literaturverzeichnis: Seite 118-133]

Nikolay, Alexander;  Reichl, Udo [AkademischeR BetreuerIn] 

Intensified yellow fever and Zika virus production in animal cell culture
In: Magdeburg, 2020, XV, 175 Seiten, Illustrationen, Diagramme, 30 cm ; [Literaturverzeichnis: Seite 139-157]

Kupke, Sascha Young;  Reichl, Udo [AkademischeR BetreuerIn] 

Single-cell analysis of influenza A virus replication - sources of cell-to-cell heterogeneity and discoverey of a novel type of defective interfering particle
In: Magdeburg, 2020, XV, 155 Seiten, Illustrationen, Diagramme, 30 cm ; [Literaturverzeichnis: Seite 122-136]

2019

Abstract

Lindquist, Jonathan;  Hennig, René;  Rapp, Erdmann;  Reichl, Udo;  Mertens, Peter Rene 

Dialyseinduzierte Veränderungen im menschlichen Serum-Protein N-Glykosylation
In: Kongress für Nephrologie, 11. Jahrestagung der Deutschen Gesellschaft für Nephrologie: Die Nephrologie als ganzheitliche Disziplin in der Patientenversorgung : 10. 13. Oktober 2019 in Düsseldorf : Programm/ Kongress für Nephrologie, 2019, P256, S. 165

Begutachteter Zeitschriftenartikel

Kupke, Sascha Young;  Riedel, Dietmar;  Frensing, Timo;  Zmora, Pawel;  Reichl, Udo 

A novel type of influenza a virus-derived defective interfering particle with nucleotide substitutions in its genome
In: Journal of virology: publ. by the American Society for Microbiology - Baltimore, Md.: Soc., 1967, Bd. 93.2019, 4, Art.-Nr. e01786, insges. 24 Seiten

Heyer, Robert;  Schallert, Kay;  Büdel, Anja;  Zoun, Roman;  Dorl, Sebastian;  Behne, Alexander;  Kohrs, Fabian;  Püttker, Sebastian;  Siewert, Corina;  Muth, Thilo;  Saake, Gunter;  Reichl, Udo;  Benndorf, Dirk 

A robust and universal metaproteomics workflow for research studies and routine diagnostics within 24 h using phenol extraction, FASP digest, and the MetaProteomeAnalyzer
In: Frontiers in microbiology - Lausanne: Frontiers Media, 2010, 10 (2019), article 1883, insgesamt 20 Seiten

Bdeir, Najat;  Arora, Prerna;  Gärtner, Sabine;  Hoffmann, Markus;  Reichl, Udo;  Pöhlmann, Stefan;  Winkler, Michael 

A system for production of defective interfering particles in the absence of infectious influenza A virus
In: PLOS ONE - San Francisco, California, US: PLOS, Vol. 14.2019, 3, Artikel e0212757, insgesamt 18 Seiten

Tapia Delgado, Felipe Ignacio;  Wohlfahrth, Daniel;  Sandig, Volker;  Jordan, Ingo;  Genzel, Yvonne;  Reichl, Udo 

Continuous influenza virus production in a tubular bioreactor system provides stable titers and avoids the von Magnus effect
In: PLOS ONE - San Francisco, California, US: PLOS, 2006, 14 (2019), 11, article e0224317, insgesamt 21 Seiten

Gränicher, Gwendal;  Coronel, Juliana;  Pralow, Alexander;  Marichal-Gallardo, Pável Alejandro;  Wolff, Michael;  Rapp, Erdmann;  Karlas, Alexander;  Sandig, Volker;  Genzel, Yvonne;  Reichl, Udo 

Efficient influenza A virus production in high cell density using the novel porcine suspension cell line PBG.PK2.1
In: Vaccine - Amsterdam: Elsevier, 1983, Bd. 37.2019, 47, S. 7019-7028

Fischöder, Thomas;  Cajic, Samanta;  Reichl, Udo;  Rapp, Erdmann;  Elling, Lothar 

Enzymatic cascade synthesis provides novel linear human milk oligosaccharides as reference standards for xCGELIF based highthroughput analysis
In: Biotechnology journal - Weinheim: Wiley-VCH, Vol. 14 (2019), 3, Artikelnr. 1800305, insges. 9 Seiten

Fischöder, Thomas;  Cajic, Samanta;  Grote, Valerian;  Greifenstein, Raphael;  Reichl, Udo;  Franzreb, Matthias;  Rapp, Erdmann;  Elling, Lothar 

Enzymatic cascades for tailored 13 C 6 and 15 N enriched human milk oligosaccharides
In: Molecules: a journal of synthetic chemistry and natural product chemistry - Basel: MDPI, 1996, Volume 24 (2019), 19, Artikel 3482, insgesamt 21 Seiten

Vázquez-Ramírez, Daniel;  Jordan, Ingo;  Sandig, Volker;  Genzel, Yvonne;  Reichl, Udo 

High titer MVA and influenza A virus production using a hybrid fed-batch/perfusion strategy with an ATF system
In: Applied microbiology and biotechnology - Berlin: Springer, Bd. 103.2019, 7, S. 3025-3035

Reiding, Karli R.;  Bondt, Albert;  Hennig, René;  Gardner, Richard A.;  O'Flaherty, Roisin;  Trbojevič-Akmačič, Irena;  Shubhakar, Archana;  Hazes, Johanna M. W.;  Reichl, Udo;  Fernandes, Daryl L.;  Pučič-Bakovič, Maja;  Rapp, Erdmann;  Spencer, Daniel I. R.;  Dolhain, Radboud J. E. M.;  Rudd, Pauline M.;  Lauc, Gordon;  Wuhrer, Manfred 

High-throughput serum N-glycomics - method comparison and application to study rheumatoid arthritis and pregnancy-associated changes
In: Molecular & cellular proteomics: MCP - Bethesda, Md: The American Society for Biochemistry and Molecular Biology, Bd. 18.2019, 1, S. 3-15

Weigel, Thomas;  Soliman, Remon;  Wolff, Michael W.;  Reichl, Udo 

Hydrophobic-interaction chromatography for purification of influenza A and B virus
In: Journal of chromatography / B - New York, NY [u.a.]: Science Direct, Bd. 1117.2019, S. 103-117

Coronel, Juliana;  Behrendt, Ilona;  Bürgin, Tim;  Anderlei, Tibor;  Sandig, Volker;  Reichl, Udo;  Genzel, Yvonne 

Influenza A virus production in a single-use orbital shaken bioreactor with ATF or TFF perfusion systems
In: Vaccine - Amsterdam: Elsevier, Bd. 37.2019, 47, S. 7011-7018

Heyer, Robert;  Schallert, Kay;  Siewert, C.;  Kohrs, F.;  Greve, J.;  Maus, I.;  Klang, J.;  Klocke, M.;  Heiermann, M.;  Hoffmann, Michael;  Püttker, Sebastian;  Calusinska, M.;  Zoun, Roman;  Saake, Gunter;  Benndorf, Dirk;  Reichl, Udo 

Metaproteome analysis reveals that syntrophy, competition, and phage-host interaction shape microbial communities in biogas plants
In: Microbiome - London: Biomed Central, 2013 . - 2019, insges. 17 S.

Lehmann, Tony;  Schallert, Kay;  Vilchez-Vargas, Ramiro;  Benndorf, Dirk;  Püttker, Sebastian;  Sydor, Svenja;  Schulz, Christian;  Bechmann, Lars Peter;  Canbay, Ali E.;  Heidrich, Benjamin;  Reichl, Udo;  Link, Alexander;  Heyer, Robert Steven 

Metaproteomics of fecal samples of Crohn's disease and Ulcerative Colitis
In: Journal of proteomics - New York, NY [u.a.]: Elsevier, 2008, Bd. 201.2019, S. 93-103

Laske, Tanja;  Bachmann, Mandy;  Dostert, Melanie;  Karlas, Alexander;  Wirth, Dagmar;  Frensing, Timo;  Meyer, Thomas F.;  Hauser, Hansjörg;  Reichl, Udo 

Modellbasierte Analyse der Influenza-A-Virus-Replikation in gentechnisch veränderten Zelllinien untersucht den Einfluss von Wirtszellfaktoren auf die wichtigsten kinetischen Parameter des Viruswachstums
In: PLoS Computational Biology - San Francisco, Calif.: Public Library of Science, Vol. 15 (2019), 2, Artikel 1006944, insgesamt 30 Seiten

Tapia Delgado, Felipe Ignacio;  Laske, Tanja;  Wasik, Milena A.;  Rammhold, Markus;  Genzel, Yvonne;  Reichl, Udo 

Production of Defective Interfering Particles of influenza A virus in parallel continuous cultures at two residence times - insights from qPCR measurements and viral dynamics modeling
In: Frontiers in Bioengineering and Biotechnology - Lausanne: Frontiers Media, 2013, Volume 7 (2019), Artikel 275, insgesamt 15 Seiten

Koch, Sabine;  Kohrs, Fabian;  Lahmann, Patrick;  Bissinger, Thomas;  Wendschuh, Stefan;  Benndorf, Dirk;  Reichl, Udo 

RedCom - a strategy for reduced metabolic modeling of complex microbial communities and its application for analyzing experimental datasets from anaerobic digestion
In: PLoS Computational Biology: a new community journal/ Public Library of Science - San Francisco, Calif.: Public Library of Science, Vol. 15 (2019), 2, Artikel e1006759, insgesamt 32 Seiten

Bissinger, Thomas;  Fritsch, Johannes;  Mihut, Adrian;  Wu, Yxiao;  Liu, Xuping;  Genzel, Yvonne;  Tan, Wen-Song;  Reichl, Udo 

Semi-perfusion cultures of suspension MDCK cells enable high cell concentrations and efficient influenza A virus productionPK2.1
In: Vaccine - Amsterdam: Elsevier, Bd. 37 (2019), 47, S. 7003-7010

Fortuna, A. Raquel;  van Teeffelen, Sebastian;  Ley, Adrian;  Fischer, Laura M.;  Taft, Florian;  Genzel, Yvonne;  Villain, Louis;  Wolff, Michael W.;  Reichl, Udo 

Use of sulfated cellulose membrane adsorbers for chromatographic purification of cell cultured-derived influenza A and B viruses
In: Separation and purification technology - Amsterdam [u.a.]: Elsevier Science, 1997, Bd. 226.2019, S. 350-358

Dissertation

Bachmann, Mandy;  Reichl, Udo [AkademischeR BetreuerIn] 

Charakterisierung der Influenzavirus-Vermehrung in genetisch veränderten humanen Zelllinien zur Optimierung der Impfstoffproduktion
In: Magdeburg, 2019, XI, 173 Seiten, Illustrationen, Diagramme, 30 cm ; [Literaturverzeichnis: Seite 133-155]

2018

Artikel in Zeitschrift

Rexer, Thomas F. T.;  Schildbach, Anna;  Klapproth, Jan;  Schierhorn, Angelika;  Mahour, Reza;  Pietzsch, Markus;  Rapp, Erdmann;  Reichl, Udo 

One pot synthesis of GDP-mannose by a multi-enzyme cascade for enzymatic assembly of lipid-linked oligosaccharides
In: Biotechnology & bioengineering - New York, NY [u.a.]: Wiley, 1959, Bd. 115 (2018), 1, S. 192-205

Begutachteter Zeitschriftenartikel

Rüdiger, D.;  Kupke, S. Y.;  Reichl, Udo 

A multiscale model of influenza A virus replication covering highly different infection conditions in cell cultures
In: IFAC-PapersOnLine/ Internationale Förderung für Automatische Lenkung - Frankfurt: Elsevier, Bd. 51.2018, 19, S. 32-33

Wasik, Milena A.;  Eichwald, Luca;  Genzel, Yvonne;  Reichl, Udo 

Cell culture-based production of defective interfering particles for influenza antiviral therapy
In: Applied microbiology and biotechnology - Berlin: Springer, 1975, Bd. 102.2018, 3, S. 1167-1177, 2017

Mahour, Reza;  Klapproth, Jan;  Rexer, Thomas F. T.;  Schildbach, Anna;  Klamt, Steffen;  Pietzsch, Markus;  Rapp, Erdmann;  Reichl, Udo 

Establishment of a five-enzyme cell-free cascade for the synthesis of uridine diphosphate N-acetylglucosamine
In: Journal of biotechnology - Amsterdam [u.a.]: Elsevier Science, Bd. 283.2018, S. 120-129

Vázquez-Ramírez, Daniel;  Genzel, Yvonne;  Jordan, Ingo;  Sandig, Volker;  Reichl, Udo 

High-cell-density cultivations to increase MVA virus production
In: Vaccine - Amsterdam: Elsevier, Bd. 36.2018, 22, S. 3124-3133

Nguyen-Khuong, Terry;  Pralow, Alexander;  Reichl, Udo;  Rapp, Erdmann 

Improvement of electrospray stability in negative ion mode for nano-PGC-LC-MS glycoanalysis via post-column make-up flow
In: Glycoconjugate journal: official journal of the International Glycoconjugate Organization - Dordrecht [u.a.]: Springer Science + Business Media B.V, Bd. 35.2018, 6, S. 499-509

Muth, Thilo;  Kohrs, Fabian;  Heyer, Robert;  Benndorf, Dirk;  Rapp, Erdmann;  Reichl, Udo;  Martens, Lennart;  Renard, Bernhard Y. 

MPA portable - a stand-alone software package for analyzing metaproteome samples on the go
In: Analytical chemistry: the authoritative voice of the analytical community - Columbus, Ohio: American Chemical Society, Bd. 90.2018, 1, S. 685-689

Duvigneau, Stefanie;  Dürr, Robert;  Laske, Tanja;  Bachmann, Mandy;  Dostert, Melanie;  Reichl, Udo;  Kienle, Achim 

Mathematical modeling as a tool to improve influenza vaccine production processes
In: IFAC-PapersOnLine/ Internationale Förderung für Automatische Lenkung - Frankfurt: Elsevier, Bd. 51.2018, 19, S. 1-4

Fortuna, Ana Raquel;  Taft, Florian;  Villain, Louis;  Wolff, Michael W.;  Reichl, Udo 

Optimization of cell culture-derived influenza A virus particles purification using sulfated cellulose membrane adsorbers
In: Engineering in life sciences - Weinheim: Wiley-VCH, Bd. 18.2018, 1, S. 29-39

Nikolay, Alexander;  Léon, Arnaud;  Schwamborn, Klaus;  Genzel, Yvonne;  Reichl, Udo 

Process intensification of EB66® cell cultivations leads to high-yield yellow fever and Zika virus production
In: Applied microbiology and biotechnology - Berlin: Springer, 1975, Bd. 102.2018, 20, S. 8725-8737

Nikolay, Alexander;  Castilho, Leda R.;  Reichl, Udo;  Genzel, Yvonne 

Propagation of Brazilian Zika virus strains in static and suspension cultures using Vero and BHK cells
In: Vaccine - Amsterdam: Elsevier, 1983, Bd. 36.2018, 22, S. 3140-3145

Fischer, Laura M.;  Wolff, Michael;  Reichl, Udo 

Purification of cell culture-derived influenza A virus via continuous anion exchange chromatography on monoliths
In: Vaccine - Amsterdam: Elsevier, Bd. 36.2018, 22, S. 3153-3160

Carvalho, Sofia B.;  Fortuna, A. Raquel;  Wolff, Michael W.;  Peixoto, Cristina;  Alves, Paula M.;  Reichl, Udo 

Purification of influenza viruslike particles using sulfated cellulose membrane adsorbers
In: Journal of chemical technology & biotechnology - Chichester: Wiley, Bd. 93.2018, 7, S. 1988-1996

Wenzel, Lisa;  Heyer, Robert;  Schallert, Kay;  Löser, Lucy;  Wünschiers, Röbbe;  Reichl, Udo;  Benndorf, Dirk 

SDSPAGE fractionation to increase metaproteomic insight into the taxonomic and functional composition of microbial communities for biogas plant samples
In: Engineering in life sciences - Weinheim: Wiley-VCH, Bd. 18.2018, 7, S. 498-509

Hoffmann, Marcus;  Pioch, Markus;  Pralow, Alexander;  Henning, René;  Kottler, Robert;  Reichl, Udo;  Rapp, Erdmann 

The fine art of destruction - a guide to indepth glycoproteomic analyses-exploiting the diagnostic potential of fragment ions
In: Proteomics - Weinheim: Wiley VCH, 2001, Vol. 18.2018, 24, Art.-Nr. 1800282

Vodovnik, Maša;  Vrabec, Katja;  Hellwig, Patrick;  Benndorf, Dirk;  Sežun, Mija;  Gregori, Andrej;  Gottumukkala, Lalitha D.;  Anderson, Robin C.;  Reichl, Udo 

Valorisation of deinking sludge as a substrate for lignocellulolytic enzymes production by Pleurotus ostreatus
In: Journal of cleaner production - Amsterdam [u.a.]: Elsevier Science, Vol. 197.2018, Part 1, S. 253-263

Pioch, Markus;  Hoffmann, Marcus;  Prahlow, Alexander;  Reichl, Udo;  Rapp, Erdmann 

glyXtoolMS - an open-source pipeline for semiautomated analysis of glycopeptide mass spectrometry data
In: Analytical chemistry: the authoritative voice of the analytical community - Columbus, Ohio: American Chemical Society, 1947, Bd. 90.2018, 20, S. 11908-11916

2017

Begutachteter Zeitschriftenartikel

Tapia, Felipe;  Jordan, Ingo;  Genzel, Yvonne;  Reichl, Udo 

Efficient and stable production of Modified Vaccinia Ankara virus in two-stage semi-continuous and in continuous stirred tank cultivation systems
In: PLoS one - Lawrence, Kan: PLoS, Bd. 12.2017, 8, Art.-Nr. e0182553, insges. 17 Seiten

Pralow, Alexander;  Hoffmann, Marcus;  Nguyen-Khuong, Terry;  Rapp, Erdmann;  Reichl, Udo 

Improvement of the glycoproteomic toolbox with the discovery of a unique C-terminal cleavage specificity of flavastacin for N-glycosylated asparagine
In: Scientific reports - [London]: Macmillan Publishers Limited, part of Springer Nature, Bd. 7.2017, Art.-Nr. 11419, insgesamt 9 Seiten

Hämmerlein, Frank;  Pieler, Michael M.;  Hennig, René;  Serve, Anja;  Rapp, Erdmann;  Wolff, Michael W.;  Reichl, Udo;  Hubbuch, Jürgen 

Influence of the production system on the surface properties of influenza A virus particles
In: Engineering in life sciences - Weinheim: Wiley-VCH, Bd. 17.2017, 10, S. 1071-1077

Kohrs, Fabian;  Heyer, Robert;  Bissinger, Thomas;  Kottler, Robert;  Schallert, Kay;  Püttker, Sebastian;  Behne, A.;  Rapp, Erdmann;  Benndorf, Dirk;  Reichl, Udo 

Proteotyping of laboratory-scale biogas plants reveals multiple steady-states in community composition
In: Anaerobe: the official journal of the Anaerobe Society of the Americas - London: Academic Press, Bd. 46.2017, S. 56-68

Pieler, Michael Martin;  Heyse, Anja;  Wolff, Michael Werner;  Reichl, Udo 

Specific ion effects on the particle size distributions of cell culturederived influenza A virus particles within the Hofmeister series
In: Engineering in life sciences - Weinheim: Wiley-VCH, Bd. 17.2017, 5, S. 470-478

Marichal-Gallardo, Pavel;  Pieler, Michael M.;  Wolff, Michael W.;  Reichl, Udo 

Steric exclusion chromatography for purification of cell culture-derived influenza A virus using regenerated cellulose membranes and polyethylene glycol
In: Journal of chromatography / A: including electrophoresis, mass spectrometry and other separation and detection methods - New York, NY [u.a.]: Science Direct, Bd. 1483.2017, S. 110-119

Buchbeitrag

Butler, M.;  Reichl, Udo 

Animal cell expression systems
In: Advances in biochemical engineering, biotechnology - Berlin: Springer, S. 1-36, 2017

Dissertation

Heyer, Robert Steven;  Reichl, Udo [GutachterIn] 

Charakterisierung von mikrobiellen Gemeinschaften aus Biogasanlagen mittels Metaproteomanalyse und Korrelationen der Ergebnisse zu den Prozessparametern
In: Magdeburg, 2017, XVII, 164, xxxvii Blätter, Illustrationen

2016

Begutachteter Zeitschriftenartikel

Pieler, Michael M.;  Frentzel, Sarah;  Bruder, Dunja;  Wolff, Michael W.;  Reichl, Udo 

A cell culture-derived whole virus influenza A vaccine based on magnetic sulfated cellulose particles confers protection in mice against lethal influenza A virus infection
In: Vaccine - Amsterdam: Elsevier, 1983, Bd. 34.2016, 50, S. 6367-6374

Weigel, Thomas;  Solomaier, Thomas;  Wehmeyer, Sebastian;  Peuker, Alessa;  Wolff, Michael W.;  Reichl, Udo 

A membrane-based purification process for cell culture-derived influenza A virus
In: Journal of biotechnology - Amsterdam [u.a.]: Elsevier Science, 1984, Bd. 220.2016, S. 12-20

Wang, Wenjing;  Voigt, Andreas;  Wolff, Michael W.;  Reichl, Udo;  Sundmacher, Kai 

Binding kinetics and multi-bond : finding correlations by synthesizing interactions between ligand-coated bionanoparticles and receptor surfaces
In: Analytical biochemistry : methods in the biological sciences. - San Diego, Calif : Elsevier, Bd. 505.2016, S. 8-17

Tapia Delgado, Felipe Ignacio;  Vázquez-Ramírez, Daniel;  Genzel, Yvonne;  Reichl, Udo 

Bioreactors for high cell density and continuous multi-stage cultivations: options for process intensification in cell culture-based viral vaccine production
In: Applied microbiology and biotechnology - Berlin: Springer, 1975, Bd. 100.2016, 5, S. 2121-2132

Bensmann, Astrid;  Hanke-Rauschenbach, Richard;  Heyer, Robert;  Kohrs, Fabian;  Benndorf, Dirk;  Kausmann, Robert;  Plöchl, Matthias;  Heiermann, Monika;  Reichl, Udo;  Sundmacher, Kai 

Diagnostic concept for dynamically operated biogas production plants
In: Renewable energy: an international journal ; the official journal of WREN, The World Renewable Energy Network - Amsterdam [u.a.]: Elsevier Science, 1991, Vol. 96.2016, Part A, S. 479-489

Cammann, Clemens;  Rath, Alexander;  Reichl, Udo;  Lingel, Holger;  Brunner-Weinzierl, Monika;  Simeoni, Luca;  Schraven, Burkhart;  Lindquist, Jonathan A. 

Early changes in the metabolic profile of activated CD8+ T cells
In: BMC cell biology - London: BioMed Central, 2000, Bd. 17.2016, Art.-Nr. 28, insges. 11 S.

Kluge, Sabine;  Genzel, Yvonne;  Laus, Kim;  Serve, Anja;  Pflugmacher, Antje;  Peschel, Britta;  Rapp, Erdmann;  Reichl, Udo 

Ezrin and HNRNP expression correlate with increased virus release rate and early onset of virus-induced apoptosis of MDCK suspension cells
In: Biotechnology journal : BTJ ; systems & synthetic biology, nanobiotech, medicine. - Weinheim : Wiley-VCH, Bd. 11.2016, 10, S. 1332-1342

Thiesler, Christina T.;  Cajic, Samanta;  Hoffmann, Dirk;  Thiel, Christian;  Diepen, Laura van;  Hennig, René;  Sgodda, Malte;  Weiβmann, Robert;  Reichl, Udo;  Steinemann, Doris;  Diekmann, Ulf;  Huber, Nicolas M. B.;  Oberbeck, Astrid;  Cantz, Tobias;  Kuss, Andreas W.;  Körner, Christian;  Schambach, Axel;  Rapp, Erdmann;  Buettner, Falk F. R. 

Glycomic characterization of induced pluripotent stem cells derived from a patient suffering from phosphomannomutase 2 congenital Disorder of glycosylation (PMM2-CDG)
In: Molecular & cellular proteomics : MCP. - Bethesda, Md : The American Society for Biochemistry and Molecular Biology, Bd. 15.2016, 4, S. 1435-1452

Bachmann, Mandy;  Breitwieser, Theresa;  Lipps, Christoph;  Wirth, Dagmar;  Jordan, Ingo;  Reichl, Udo;  Frensing, Timo 

Impaired antiviral response of adenovirus-transformed cell lines supports virus replication
In: Journal of general virology: JGV - Reading: Soc., 1967, Bd. 97.2016, 2, S. 293-298

Frensing, Timo;  Kupke, Sascha Young;  Bachmann, Mandy;  Fritzsche, Susanne;  Gallo-Ramirez, Lili E.;  Reichl, Udo 

Influenza virus intracellular replication dynamics, release kinetics, and particle morphology during propagation in MDCK cells
In: Applied microbiology and biotechnology - Berlin: Springer, 1975, Bd. 100.2016, 16, S. 7181-7192

Salerno, Carlo;  Benndorf, Dirk;  Pech, Sabine;  Palese, Luigi Leonardo;  Reichl, Udo;  Pollice, Alfieri 

Metaproteomics applied to activated sludge for industrial wastewater treatment revealed a dominant methylotrophic metabolism of Hyphomicrobium zavarzinii
In: Microbial ecology - New York, NY: Springer, 1974 . - 2016

Koch, Sabine;  Benndorf, Dirk;  Fronk, Karen;  Reichl, Udo;  Klamt, Steffen 

Predicting compositions of microbial communities from stoichiometric models with applications for the biogas process
In: Biotechnology for biofuels. - London : BioMed Central, Bd. 9.2016, 17, insges. 16 S.

Heyer, Robert;  Benndorf, Dirk;  Kohrs, F.;  Vrieze, J.;  Boon, N.;  Hoffmann, M.;  Rapp, Erdmann;  Schlüter, A.;  Sczyrba, A.;  Reichl, Udo 

Proteotyping of biogas plant microbiomes separates biogas plants according to process temperature and reactor type
In: Biotechnology for biofuels - London: BioMed Central, 2008, Bd. 9.2016, 1

Laske, Tanja;  Heldt, Frank Stefan;  Hoffmann, Helene;  Frensing, Timo;  Reichl, Udo 

Reprint of "Modeling the intracellular replication of influenza A virus in the presence of defective interfering RNAs
In: Virus research : an international journal of molecular and cellular virology. - Amsterdam [u.a.] : Elsevier Science, Bd. 218.2016, S. 86-95

Meininger, M.;  Stepath, M.;  Hennig, R.;  Cajic, S.;  Rapp, E.;  Rotering, H.;  Wolff, M. W.;  Reichl, Udo 

Sialic acid-specific affinity chromatography for the separation of erythropoietin glycoforms using serotonin as a ligand
In: Journal of chromatography / B - New York, NY [u.a.]: Science Direct, 1977, Bd. 1012/1013.2016, S. 193-203

Hoffmann, Marcus;  Marx, Kristina;  Reichl, Udo;  Wuhrer, Manfred;  Rapp, Erdmann 

Site-specific O-glycosylation analysis of human blood plasma proteins
In: Molecular & cellular proteomics: MCP - Bethesda, Md: The American Society for Biochemistry and Molecular Biology, 2002, Bd. 15.2016, 2, S. 624-641

Hennig, René;  Cajic, Samanta;  Borowiak, Matthias;  Hoffmann, Marcus;  Kottler, Robert;  Reichl, Udo;  Rapp, Erdmann 

Towards personalized diagnostics via longitudinal study of the human plasma N-glycome
In: Biochimica et biophysica acta / General subjects: BBA - Amsterdam [u.a.]: Elsevier, 1964, Bd. 1860.2016, 8, S. 1728-1738

2015

Begutachteter Zeitschriftenartikel

Gallo-Ramírez, Lilí Esmeralda;  Nikolay, Alexander;  Genzel, Yvonne;  Reichl, Udo 

Bioreactor concepts for cell culture-based viral vaccine production
In: Expert review of vaccines - Abingdon, Oxon: Taylor & Francis, 2002, Bd. 14.2015, 9, S. 1181-1195

Kolmeder, Carolin A.;  Ritari, Jarmo;  Verdam, Froukje J.;  Muth, Thilo;  Keskitalo, Salla;  Varjosalo, Markku;  Fuentes, Susana;  Greve, Jan Willem;  Buurman, Wim A.;  Reichl, Udo;  Rapp, Erdmann;  Martens, Lennart;  Palva, Airi;  Salonen, Anne;  Rensen, Sander S.;  Vos, Willem M. 

Colonic metaproteomic signatures of active bacteria and the host in obesity
In: Proteomics - Weinheim: Wiley VCH, 2001, Bd. 15.2015, 20, S. 3544-3552

Theuerl, Susanne;  Kohrs, Fabian;  Benndorf, Dirk;  Maus, Irena;  Wibberg, Daniel;  Schlüter, Andres;  Kausmann, Robert;  Heiermann, Monika;  Rapp, Erdmann;  Reichl, Udo;  Pühler, Alfred;  Klocke, Michael 

Community shifts in a well-operating agricultural biogas plant - how process variations are handled by the microbiome
In: Applied microbiology and biotechnology - Berlin: Springer, Bd. 99.2015, 18, S. 7791-7803

Serve, Anja;  Pieler, Michael Martin;  Benndorf, Dirk;  Rapp, Erdmann;  Wolff, Michael Werner;  Reichl, Udo 

Comparison of influenza virus particle purification using magnetic sulfated cellulose particles with an established centrifugation method for analytics
In: Analytical chemistry : the authoritative voice of the analytical community. - Columbus, Ohio : American Chemical Society, Bd. 87.2015, 21, S. 10708-10711

Grabherr, Reingard;  Reichl, Udo 

Editorial: Can modern vaccine technology pursue the success of traditional vaccine manufacturing?
In: Biotechnology journal: BTJ : systems & synthetic biology, nanobiotech, medicine - Weinheim: Wiley-VCH, Bd. 10.2015, 5, S. 657-658

Karsten, Christina B.;  Buettner, Falk F. R.;  Cajic, Samanta;  Nehlmeier, Inga;  Neumann, Berit;  Klippert, Antonina;  Sauermann, Ulrike;  Reichl, Udo;  Gerardy-Schahn, Rita;  Rapp, Erdmann;  Stahl-Hennig, Christiane;  Pöhlmann, Stefan 

Exclusive decoration of simian immunodeficiency virus Env with high-mannose type N-glycans is not compatible with mucosal transmission in rhesus macaques
In: Journal of virology: publ. by the American Society for Microbiology - Baltimore, Md.: Soc., 1967, Bd. 89.2015, 22, S. 11727-11733

Kohrs, Fabian;  Wolter, Sophie;  Benndorf, Dirk;  Heyer, Robert;  Hoffmann, Marcus;  Rapp, Erdmann;  Bremges, Andreas;  Sczyrba, Alexander;  Schlüter, Andreas;  Reichl, Udo 

Fractionation of biogas plant sludge material improves metaproteomic characterization to investigate metabolic activity of microbial communities
In: Proteomics - Weinheim: Wiley VCH, 2001, Bd. 15.2015, 20, S. 3585-3589

Püttker, Sebastian;  Kohrs, Fabian;  Benndorf, Dirk;  Heyer, Robert;  Rapp, Erdmann;  Reichl, Udo 

Metaproteomics of activated sludge from a wastewater treatment plant - a pilot study
In: Proteomics - Weinheim: Wiley VCH, 2001, Bd. 15.2015, 20, S. 3596-3601

Heyer, Robert;  Kohrs, Fabian;  Reichl, Udo;  Benndorf, Dirk 

Metaproteomics of complex microbial communities in biogas plants
In: Microbial biotechnology - Oxford: Wiley-Blackwell, 2008, Bd. 8.2015, 5, S. 749-763

Laske, Tanja;  Heldt, Frank Stefan;  Hoffmann, Helene;  Frensing, Timo;  Reichl, Udo 

Modeling the intracellular replication of influenza A virus in the presence of defective interfering RNAs
In: Virus research: an international journal of molecular and cellular virology - Amsterdam [u.a.]: Elsevier Science, 1984, Bd. 213.2015, S. 90-99

Pech, Sabine;  Benndorf, Dirk;  Genzel, Yvonne;  Scharfenberg, Klaus;  Rapp, Erdmann;  Reichl, Udo 

Monitoring changes in proteome during stepwise adaptation of a MDCK cell line from adherence to growth in suspension
In: Vaccine - Amsterdam: Elsevier, 1983, Bd. 33.2015, 35, S. 4269-4280

Muth, Thilo;  Kolmeder, Carolin A.;  Salojärvi, Jarkko;  Keskitalo, Salla;  Varjosalo, Markku;  Verdam, Froukje J.;  Rensen, Sander S.;  Reichl, Udo;  Vos, Willem M.;  Rapp, Erdmann;  Martens, Lennart 

Navigating through metaproteomics data - a logbook of database searching
In: Proteomics - Weinheim: Wiley VCH, 2001, Bd. 15.2015, 20, S. 3439-3453

Heldt, Frank S.;  Kupke, Sascha Young;  Dorl, Sebastian;  Reichl, Udo;  Frensing, Timo 

Single-cell analysis and stochastic modelling unveil large cell-to-cell variability in influenza A virus infection
In: Nature Communications - [London]: Nature Publishing Group UK, 2010, Vol. 6.2015, Art. 8938, insgesamt 12 S.

Muth, Thilo;  Behne, Alexander;  Heyer, Robert;  Kohrs, Fabian;  Benndorf, Dirk;  Hoffmann, Marcus;  Lehtevä, Miro;  Reichl, Udo;  Martens, Lennart;  Rapp, Erdmann 

The MetaProteomeAnalyzer - a powerful open-source software suite for metaproteomics data analysis and interpretation
In: Journal of proteome research - Washington, DC: ACS Publications, 2002, Bd. 14.2015, 3, S. 1557-1565

Dissertation

Müller, Thomas;  Kienle, Achim [Gutachter];  Reichl, Udo [Gutachter] 

Population balance modeling of influenza A virus replication in MDCK cells during vaccine production
In: Magdeburg Univ., Fak. für Elektrotechnik und Informationstechnik, Diss., 2015, X, 127 S., graph. Darst.

2014

Begutachteter Zeitschriftenartikel

Weigel, Thomas;  Solomaier, Thomas;  Peuker, Alessa;  Pathapati, Trinath;  Wolff, Michael W.;  Reichl, Udo 

A flow-through chromatography process for influenza A and B virus purification
In: Journal of virological methods - Amsterdam [u.a.]: Elsevier Science, Bd. 207.2014, S. 45-53

Wang, Wenjing;  Wolff, Michael W.;  Reichl, Udo;  Sundmacher, Kai 

Avidity of influenza virus: Model-based identification of adsorption kinetics from surface plasmon resonance experiments
In: Journal of chromatography / A - New York, NY [u.a.]: Science Direct, Bd. 1326.2014, S. 125-129

Bensmann, Astrid;  Hanke-Rauschenbach, R.;  Heyer, Robert;  Kohrs, Fabian;  Benndorf, Dirk;  Reichl, Udo;  Sundmacher, Kai 

Biological methanation of hydrogen within biogas plants - a model-based feasibility study
In: Applied energy - Amsterdam [u.a.]: Elsevier Science, Bd. 134.2014, S. 413-425

Rehberg, M.;  Rath, A.;  Ritter, J. B.;  Genzel, Y.;  Reichl, Udo 

Changes in intracellular metabolite pools during growth of adherent MDCK cells in two different media
In: Applied microbiology and biotechnology - Berlin: Springer, Bd. 98.2014, 1, S. 385-397

Huffman, Jennifer E.;  Pučić-Baković, Maja;  Klarić, Lucija;  Hennig, René;  Selman, Maurice H. J.;  Vučković, Frano;  Novokmet, Mislav;  Krištić, Jasminka;  Borowiak, Matthias;  Muth, Thilo;  Polašek, Ozren;  Razdorov, Genadij;  Gornik, Olga;  Plomp, Rosina;  Theodoratou, Evropi;  Wright, Alan F.;  Rudan, Igor;  Hayward, Caroline;  Campbell, Harry;  Deelder, André M.;  Reichl, Udo;  Aulchenko, Yurii S.;  Rapp, Erdmann;  Wuhrer, Manfred;  Lauc, Gordan 

Comparative performance of four methods for high-throughput glycosylation analysis of immunoglobulin G in genetic and epidemiological
In: Molecular & cellular proteomics: MCP - Bethesda, Md: The American Society for Biochemistry and Molecular Biology, Bd. 13.2014, S. 1598-1610

Bensch, Gerald;  Rüger, Marc;  Wassermann, Magdalena;  Weinholz, Susann;  Reichl, Udo;  Cordes, Christiana 

Flow cytometric viability assessment of lactic acid bacteria starter cultures produced by fluidized bed drying
In: Applied microbiology and biotechnology - Berlin: Springer, Bd. 98.2014, 11, S. 4897-4909

Rehberg, Markus;  Ritter, Joachim B.;  Reichl, Udo 

Glycolysis is governed by growth regime and simple enzyme regulation in adherent MDCK cells
In: PLoS Computational Biology: a new community journal - San Francisco, Calif: Public Library of Science, Vol. 10.2014, 10, Art. e1003885, insgesamt 16 S.

Genzel, Yvonne;  Vogel, Thomas;  Buck, Johannes;  Behrendt, Ilona;  Vazquez Ramirez, Daniel;  Schiedner, Gudrun;  Jordan, Ingo;  Reichl, Udo 

High cell density cultivations by alternating tangential flow (ATF) perfusion for influenza A virus production using suspension cells
In: Vaccine - Amsterdam: Elsevier, Bd. 32.2014, 24, S. 2770-2781

Rödig, Jana;  Rapp, Erdmann;  Bohne, Jana;  Kampe, Michael;  Kaffka, Helene;  Bock, Andreas;  Genzel, Yvonne;  Reichl, Udo 

Impact of cultivation conditions on N-glycosylation of influenza virus A hemagglutinin produced in MDCK cell culture
In: Biotechnology & bioengineering - New York, NY [u.a.]: Wiley, 1959, Bd. 110.2014, 6, S. 1691-1703

Frensing, Timo;  Pflugmacher, Antje;  Bachmann, Mandy;  Peschel, Britta;  Reichl, Udo 

Impact of defective interfering particles on virus replication and antiviral host response in cell culture-based influenza vaccine production
In: Applied microbiology and biotechnology - Berlin: Springer, 1975, Bd. 98.2014, 21, S. 8999-9008

Tapia Delgado, Felipe Ignacio;  Vogel, Thomas;  Genzel, Yvonne;  Behrendt, Ilona;  Hirschel, Mark;  Gangemi, J. David;  Reichl, Udo 

Production of high-titer human influenza A virus with adherent and suspension MDCK cells cultured in a single-use hollow fiber bioreactor
In: Vaccine - Amsterdam: Elsevier, 1983, Bd. 32.2014, 8, S. 1003-1011

Kohrs, Fabian;  Heyer, Robert;  Magnussen, A.;  Benndorf, Dirk;  Muth, T.;  Behne, A.;  Rapp, E.;  Kausmann, R.;  Heiermann, M.;  Klocke, M.;  Reichl, Udo 

Sample prefractionation with liquid isoelectric focusing enables in depth microbial metaproteome analysis of mesophilic and thermophilic biogas plants
In: Anaerobe: the official journal of the Anaerobe Society of the Americas - London: Academic Press, Bd. 29.2014, S. 59-67

Rüger, Marc;  Ackermann, Mandy;  Reichl, Udo 

Species-specific viability analysis of Pseudomonas aeruginosa, Burkholderia cepacia and Staphylococcus aureus in mixed culture by flow cytometry
In: BMC microbiology - London: BioMed Central, Bd. 14.2014, Art. 56, insgesamt 15 S.

Lohr, Verena;  Hädicke, Oliver;  Genzel, Yvonne;  Jordan, Ingo;  Büntemeyer, Heino;  Klamt, Steffen;  Reichl, Udo 

The avian cell line AGE1.CR.pIX characterized by metabolic flux analysis
In: BMC biotechnology - London: BioMed Central, Vol. 14.2014, Art. 72 insgesamt 14 S.

Rath, Alexander;  Rehberg, Markus;  Janke, Robert;  Genzel, Yvonne;  Scholz, Sebastian;  Noll, Thomas;  Rose, Thomas;  Sandig, Volker;  Reichl, Udo 

The influence of cell growth and enzyme activity changes on intracellular metabolite dynamics in AGE1.HN.AAT cells
In: Journal of biotechnology - Amsterdam [u.a.]: Elsevier Science, Bd. 178.2014, S. 43-53

Buchbeitrag

Genzel, Yvonne;  Rödig, Jana;  Rapp, Erdmann;  Reichl, Udo 

Vaccine production - upstream processing with adherent or suspension cell lines
In: Animal Cell Biotechnology - Totowa, NJ: Humana Press, 2014 . - 2014, S. 371-393 - (Methods in Molecular Biology, Methods and Protocols; 1104)

Dissertation

Lohr, Verena;  Reichl, Udo [Gutachter] 

Characterization of the avian designer cells AGE1.CR and AGE1.CR.plX considering growth, metabolism and production of influenza virus and Modified Vaccinia Virus Ankara (MVA)
In: Magdeburg, Univ., Fak. für Verfahrens- und Systemtechnik, Diss., 2014, IX, 178 S., Ill., graph. Darst., 30 cm

Rödig, Jana Verena;  Reichl, Udo [Gutachter] 

Impact of cultivation conditions on N-glycosylation of influenza A virus hemagglutinin, on quasispecies composition, and on immunogenicity of virus preparations
In: Magdeburg, Univ., Fak. für Verfahrens- und Systemtechnik, Diss., 2014, XVII, 159, S44 Bl., graph. Darst.

Habilitation

Pohlscheidt, Michael;  Reichl, Udo [Gutachter] 

Improving industrial antibody manufacturing processes using animal cell culture technology
In: Magdeburg, Univ., Fak. für Verfahrens- und Systemtechnik, Habil.-Schr., 2014, Getr. Zählung, Ill., graph. Darst., 30 cm

Herausgeberschaft

Benner, Peter;  Findeisen, Rolf [Hrsg.];  Flockerzi, Dietrich [Hrsg.];  Reichl, Udo [Hrsg.];  Sundmacher, Kai [Hrsg.] 

Large-Scale Networks in Engineering and Life Sciences
In: Cham: Birkhäuser, 2014, Online-Ressource (XIV, 388 p. 111 illus., 63 illus. in color, online resource) - (Springer eBook Collection; Mathematics and Statistics; SpringerLink; Bücher; Modeling and Simulation in Science, Engineering and Technology)

Benner, Peter;  Findeisen, Rolf;  Flockerzi, Dietrich;  Reichl, Udo;  Sundmacher, Kai 

Large-Scale Networks in Engineering and Life Sciences
In: Heidelberg [u.a.], Springer, Imprint: Birkhäuser, 2014, Online-Ressource (XIV, 388 p. 111 illus., 63 illus. in color), online resource - (Modeling and Simulation in Science, Engineering and Technology)

2013

Begutachteter Zeitschriftenartikel

Freund, Susann;  Rath, Alexander;  Barradas, Oscar Platas;  Skerhutt, Eva;  Scholz, Sebastian;  Niklas, Jens;  Sandig, Volker;  Rose, Thomas;  Heinzle, Elmar;  Noll, Thomas;  Pörtner, Ralf;  Zeng, An-Ping;  Reichl, Udo 

Batch-to-batch variability of two human designer cell lines - AGE1.HN and AGE1.HN.AAT ; carried out by different laboratories under defined culture conditions using a mathematical model
In: Engineering in life sciences - Weinheim: Wiley-VCH, 2001, Bd. 13.2013, 6, S. 580-592

Genzel, Yvonne;  Behrendt, Ilona;  Rödig, Jana;  Rapp, Erdmann;  Kueppers, Claudia;  Kochanek, Stefan;  Schiedner, Gudrun;  Reichl, Udo 

CAP, a new human suspension cell line for influenza virus production
In: Applied microbiology and biotechnology - Berlin: Springer, 1975, Bd. 97.2013, 1, S. 111-122, 2012

Peschel, B.;  Frentzel, S.;  Laske, T.;  Genzel, Y.;  Reichl, Udo 

Comparison of influenza virus yields and apoptosis-induction in an adherent and a suspension MDCK cell line
In: Vaccine. - Amsterdam : Elsevier, Bd. 31.2013, 48, S. 5693-5699

Frensing, Timo;  Stefan, Frank;  Pflugmacher, Antje;  Behrendt, Ilona;  Jordan, Ingo;  Flockerzi, Dietrich;  Genzel, Yvonne;  Reichl, Udo 

Continuous influenza virus production in cell culture shows a periodic accumulation of defective interfering particles
In: PLOS ONE - San Francisco, California, US: PLOS, 2006, Vol. 8.2013, 9, Art. e72288, insgesamt 9 S.

Kröber, T.;  Wolff, M. W.;  Hundt, B.;  Seidel-Morgenstern, Andreas;  Reichl, Udo 

Continuous purification of influenza virus using simulated moving bed chromatography
In: Journal of chromatography. - New York, NY [u.a.] : Science DirectJournal of chromatography / A, Bd. 1307.2013, S. 99-110

Kottler, Robert;  Mank, Marko;  Hennig, René;  Müller-Werner, Beate;  Stahl, Bernd;  Reichl, Udo;  Rapp, Erdmann 

Development of a high-throughput glycoanalysis method for the characterization of oligosaccharides in human milk utilizing multiplexed capillary gel electrophoresis with laser-induced fluorescence detection
In: Electrophoresis. - Weinheim : Wiley-Blackwell, Bd. 34.2013, 16, S. 2323-2336

Müller, Thomas;  Dürr, Robert;  Isken, Britta;  Schulze-Horsel, Josef;  Reichl, Udo;  Kienle, Achim 

Distributed modeling of human influenza a virushost cell interactions during vaccine production
In: Biotechnology & bioengineering. - New York, NY [u.a.] : Wiley, Bd. 110.2013, 8, S. 2252-2266

Jordan, Ingo;  Lohr, Verena;  Genzel, Yvonne;  Reichl, Udo;  Sandig, Volker 

Elements in the development of a production process for modified vaccinia virus ankara
In: Microorganisms. - Basel : MDPI, Bd. 1.2013, 1, S. 100-121

Hädicke, O.;  Lohr, V.;  Genzel, Y.;  Reichl, Udo;  Klamt, S. 

Evaluating differences of metabolic performances - statistical methods and their application to animal cell cultivations
In: Biotechnology & bioengineering. - New York, NY [u.a.] : Wiley, Bd. 110.2013, 10, S. 2633-2642

Genzel, Yvonne;  Frensing, Timo;  Reichl, Udo 

Herstellung moderner Grippeimpfstoffe
In: Chemie in unserer Zeit. - Weinheim : Wiley-VCH, Bd. 47.2013, 1, S. 12-22

Borchers, Steffen;  Freund, Susann;  Rath, Alexander;  Streif, Stefan;  Reichl, Udo;  Findeisen, Rolf 

Identification of growth phases and influencing factors in cultivation of AGE1.HN cells using set-based methods
In: PLOS ONE - San Francisco, California, US: PLOS, 2006, Vol. 8.2013, 8, Art. e68124, insgesamt 11 S.

Hanreich, Angelika;  Schimpf, Ulrike;  Zakrzewski, Martha;  Schlüter, Andreas;  Benndorf, Dirk;  Heyer, Robert;  Rapp, Erdmann;  Pühler, Alfred;  Reichl, Udo;  Klocke, Michael 

Metagenome and metaproteome analyses of microbial communities in mesophilic biogas-producing anaerobic batch fermentations indicate concerted plant carbohydrate degradation
In: Systematic and applied microbiology - München: Elsevier, Bd. 36.2013, 5, S. 330-338

Heyer, Robert;  Kohrs, Fabian;  Benndorf, Dirk;  Rapp, E.;  Kausmann, R.;  Heiermann, M.;  Klocke, M.;  Reichl, Udo 

Metaproteome analysis of the microbial communities in agricultural biogas plants
In: New biotechnology - New York, NY [u.a.]: Elsevier, 2008, Bd. 30.2013, 6, S. 614-622

Heldt, Frank S.;  Frensing, Timo;  Pflugmacher, Antje;  Gröpler, Robin;  Peschel, Britta;  Reichl, Udo 

Multiscale modeling of influenza A virus infection supports the development of direct-acting antivirals
In: PLoS Computational Biology: a new community journal/ Public Library of Science - San Francisco, Calif.: Public Library of Science, 2005, Bd. 9.2013, 11, Art. e1003372, insges. 13 S.

Neumann, A.;  Hoyer, W.;  Wolff, M. W.;  Reichl, Udo;  Pfitzner, A.;  Roth, B. 

New method for density determination of nanoparticles using a CPS disc centrifuge
In: Colloids and surfaces. - Amsterdam [u.a.] : Elsevier ScienceColloids and surfaces / B, Bd. 104.2013, S. 27-31

Tung, Stephanie;  Shi, Yonghong;  Wong, Karry;  Zhu, Fang;  Gorczynski, Reg;  Laister, Robert C.;  Minden, Mark;  Blechert, Anne-Kareen;  Genzel, Yvonne;  Reichl, Udo;  Spaner, David E. 

PPARα and fatty acid oxidation mediate glucocorticoid resistance in chronic lymphocytic leukemia
In: Blood. - Stanford, Calif : HighWire Press, Bd. 112.2013, 6, S. 969-980

Pech, Sabine;  Rourou, Samia;  Vester, Diana;  Majoul, Samy;  Genzel, Yvonne;  Rapp, Erdmann;  Kallel, Héla;  Reichl, Udo 

Proteome analysis of virushost cell interaction - rabies virus replication in Vero cells in two different media
In: Applied microbiology and biotechnology - Berlin: Springer, 1975, Bd. 97.2013, 12, S. 5493-5506

Benndorf, Dirk;  Reichl, Udo 

Proteomics in environmental and technical microbiology
In: Engineering in life sciences - Weinheim: Wiley-VCH, 2001, Bd. 14.2013, 1, S. 27-46

Muth, Thilo;  Brenndorf, Dirk;  Reichl, Udo;  Rapp, Erdmann;  Martens, Lennart 

Searching for a needle in a stack of needles: challenges in metaproteomics data analysis
In: Molecular BioSystems. - Cambridge : Royal Society of Chemistry, Bd. 9.2013, 4, S. 578-585

Hütter, Julia;  Rödig, Jana;  Höper, Dirk;  Seeberger, Peter H.;  Reichl, Udo;  Rapp, Erdmann;  Lepenies, Bernd 

Toward animal cell culturebased influenza vaccine design - viral hemagglutinin N-glycosylation markedly impacts immunogenicity
In: The journal of immunology - Bethesda, Md.: Soc., 1916, Bd. 19.2013, 1, S. 220-230

Behne, Alexander;  Muth, Thilo;  Borowiak, Matthias;  Reichl, Udo;  Rapp, Erdmann 

glyXalign - high-throughput migration time alignment preprocessing of electrophoretic data retrieved via multiplexed capillary gel electrophoresis with laser-induced fluorescence detection-based glycoprofiling
In: Electrophoresis. - Weinheim : Wiley-Blackwell, Bd. 34.2013, 16, S. 2311-2315

Originalartikel in begutachteter internationaler Zeitschrift

Rehberg, M.;  Ritter, J. B.;  Genzel, Y.;  Flockerzi, D.;  Reichl, Udo 

The relation between growth phases, cell volume changes and metabolism of adherent cells during cultivation
In: Journal of biotechnology. - Amsterdam [u.a.] : Elsevier Science, Bd. 164.2013, 4, S. 489-499

2012

Abstract

Hütter, J.;  Rödig, Jana;  Höper, D.;  Reichl, Udo;  Seeberger, P. H.;  Rapp, E.;  Lepenies, B. 

Glycosylation matters - role of viral hemagglutinin N-glycosylation in immunogenicity
In: Immunology: an official journal of the British Society for Immunology - Oxford [u.a.]: Wiley-Blackwell, 1958, Vol. 137, 2012, Suppl. 1, Art. P1880, S. 760

Artikel in Kongressband

Dürr, Robert;  Müller, Thomas;  Isken, Britta;  Schulze-Horstel, Josef;  Reichl, Udo;  Kienle, Achim 

Distributed modeling and parameter estimation of influenza virus replication during vaccine production authors
In: Preprints MATHMOD 2012 Vienna: abstract volume - Vienna: ARGESIM, ARGE Simulation News, Vienna Univ. of Technology, insges. 6 S. - (ARGESIM report; 38)

Begutachteter Zeitschriftenartikel

Rüger, Marc;  Bensch, Gerald;  Tüngler, Ralf;  Reichl, Udo 

A flow cytometric method for viability assessment of Staphylococcus aureus and Burkholderia cepacia in mixed culture
In: Cytometry / A - Hoboken, NJ: Wiley-Liss, Bd. 81.2012, 12, S. 1055-1066

Platas Barradas, Oscar;  Jandt, Uwe;  Phan, Linh Da Minh;  Villanueva, Mario E.;  Schaletzky, Martin;  Rath, Alexander;  Freund, Susann;  Reichl, Udo;  Skerhutt, Eva;  Scholz, Sebastian;  Noll, Thomas;  Sandig, Volker;  Pörtner, Ralf;  Zeng, An-Ping 

Evaluation of criteria for bioreactor comparison and operation standardization for mammalian cell culture
In: Engineering in life sciences - Weinheim: Wiley-VCH, 2001, Bd. 12.2012, 5, S. 518-528

Carrondo, Manuel J. T.;  Alves, Paula M.;  Carinhas, Nuno;  Glassey, Jarka;  Hesse, Friedemann;  Merten, Otto-Wilhelm;  Micheletti, Martina;  Noll, Thomas;  Oliveira, Rui;  Reichl, Udo;  Staby, Arne;  Teixeira, Ana P.;  Weichert, Henry;  Mandenius, Carl-Fredrik 

How can measurement, monitoring, modeling and control advance cell culture in industrial biotechnology?
In: Biotechnology journal: BTJ : systems & synthetic biology, nanobiotech, medicine - Weinheim: Wiley-VCH, Bd. 7.2012, 12, S. 1522-1529

Lohr, Verena;  Genzel, Yvonne;  Jordan, Ingo;  Katinger, Dietmar;  Mahr, Stefan;  Sanding, Volker;  Reichl, Udo 

Live attenuated influenza viruses produced in a suspension process with avian AGE1.CR.pIX cells
In: BMC biotechnology - London: BioMed Central, 12.2012, Art. 79, insgesamt 9 S.

Hanreich, Angelika;  Heyer, Robert;  Benndorf, Dirk;  Rapp, Erdmann;  Pioch, Markus;  Reichl, Udo;  Klocke, Michael 

Metaproteome analysis to determine the metabolically active part of a thermophilic microbial community producing biogas from agricultural biomass
In: Canadian journal of microbiology / publ. by the National Research Council of Canada - Plattsburgh, NY: NRC Research Press, 1954, Bd. 58.2012, 7, S. 917-922; =A http://dx.doi.org/10.1139/W2012-058

Heldt, Frank S.;  Frensing, Timo;  Reichl, Udo 

Modeling the intracellular dynamics of influenza virus replication to understand the control of viral RNA synthesis
In: Journal of virology: publ. by the American Society for Microbiology - Baltimore, Md: Soc, Bd. 86.2012, 15, S. 7806-7817

Isken, B.;  Genzel, Y.;  Reichl, Udo 

Productivity, apoptosis, and infection dynamics of influenza A/PR/8 strains and A/PR/8-based reassortants
In: Vaccine - Amsterdam: Elsevier, Bd. 30.2012, 35, S. 5253-5261

Dissertation

Bock, Andreas;  Reichl, Udo [Gutachter] 

Überwachung und Regelung von Hochzelldichtekultivierungen in der Influenza-Impfstoffproduktion
In: Zugl.: Magdeburg, Univ., Fak. für Verfahrens- und Systemtechnik, Diss., 2012: Aachen: Shaker, XI, 175 S., Ill., graph. Darst., 210 mm x 148 mm, 300 g - (Forschungsberichte aus dem Max-Planck-Institut für Dynamik komplexer technischer Systeme; 33)

Originalartikel in begutachteter internationaler Zeitschrift

Popov, Mladen;  Nacheva, Genoveva;  Reichl, Udo;  Ivanov, Ivan 

Effect of the 3'-terminal truncation of the human interferon-gamma gene on plasmid segregation in escherichia coli
In: Biotechnology & biotechnological equipment: international scientific-theoretical and applied publication - London: Taylor and Francis, Bd. 26.2012, 2, S. 2930-2936

Rödig, Jana;  Rapp, Erdmann;  Höper, Dirk;  Genzel, Yvonne;  Reichl, Udo 

Impact of host cell line adaptation on quasispecies composition and glycosylation of influenza A virus hemagglutinin
In: PLOS ONE - San Francisco, California, US: PLOS, 2006, Vol. 6, 2012, 12, Art. e27989, insgesamt 10 S.

Kluge, Sabine;  Hoffmann, Marcus;  Benndorf, Dirk;  Rapp, Erdmann;  Reichl, Udo 

Proteomic tracking and analysis of a bacterial mixed culture
In: Proteomics: proteomics and systems biology - Weinheim: Wiley-VCH, 2001, Bd. 12.2012, 12, S. 1893-1901

Riedele, Christian;  Reichl, Udo 

Time-kill studies with a ceftazidime-treated mixed culture consisting of Pseudomonas aeruginosa, Burkholderia cepacia and Staphylococcus aureus
In: Engineering in life sciences: Industry, Environment, Plant, Food - Weinheim: Wiley-Blackwell, Bd. 12.2012, 2, S. 188-197

Seitz, Claudia;  Isken, Britta;  Heynisch, Björn;  Rettkowski, Maria;  Frensing, Timo;  Reichl, Udo 

Trypsin promotes efficient influenza vaccine production in MDCK cells by interfering with the antiviral host response
In: Applied microbiology and biotechnology - Berlin: Springer, Bd. 93.2012, 2, S. 601-611

2011

Dissertation

Vester, Diana;  Reichl, Udo 

Molecular biological analysis of dynamic interactions between influenza viruses and host cells - host cell proteomes and viral replication dynamics
In: Magdeburg, Univ., Fak. für Naturwiss., Diss., 2011, XVIII, 176 S., graph. Darst.

Originalartikel in begutachteter internationaler Zeitschrift

Schmidt, Julia K.;  Riedele, Christian;  Regestein, Lars;  Rausenberger, Julia;  Reichl, Udo 

A novel concept combining experimental and mathematical analysis for the identification of unknown interspecies effects in a mixed culture
In: Biotechnology and bioengineering. - New York, NY [u.a.] : Wiley, Bd. 108.2011, 8, S. 1900-1911

Schräder, Eva;  Scholz, Sebastian;  Niklas, Jens;  Rath, Alexander;  Platas Barradas, Oscar;  Jandt, Uwe;  Sandig, Volker;  Rose, Thomas;  Pörtner, Ralf;  Reichl, Udo;  Zeng, An-Ping;  Heinzle, Elmar;  Noll, Thomas 

Characterisation of cultivation of the human cell line AGE1.HN.AAT
In: BMC proceedings - London: BioMed Central, 2007, 2011 Suppl. 8, P87

Scholz, Sebastian;  Luebbecke, Miriam;  Rath, Alexander;  Schräder, Eva;  Rose, Thomas;  Büntemeyer, Heino;  Scheper, Thomas;  Reichl, Udo;  Noll, Thomas 

Characterization of the human AGE1.HN cell line: a systems biology approach
In: BMC proceedings - London: BioMed Central, 2007, 2011, Suppl. 8, P78

Platas Barradas, Oscar;  Jandt, Uwe;  Phan, Linh Da Minh;  Villanueva, Mario;  Rath, Alexander;  Reichl, Udo;  Schräder, Eva;  Scholz, Sebastian;  Noll, Thomas;  Sandig, Volker;  Zeng, An-Ping;  Pörtner, Ralf 

Criteria for bioreactor comparison and operation standardisation during process development for mammalian cell culture
In: BMC proceedings/ Biomed Central - London: BioMed Central, 2007, 2011, Suppl. 8, P47

W Wolf, Michael;  Reichl, Udo 

Downstream processing of cell culture-derived virus particles
In: Expert review of vaccines. - London : Expert Reviews, Bd. 10.2011, 10, S. 1451-1475

Popov, Mladen;  Petrov, Stefan;  Nacheva, Genoveva;  Ivanov, Ivan;  Reichl, Udo 

Effects of a recombinant gene expression on ColE1-like plasmid segregation in Escherichia coli
In: BMC biotechnology. - London : BioMed Central, Bd. 11.2011, 18, insges. 12 S.

Frensing, Timo;  Seitz, Claudius;  Heynisch, Bjoern;  Patzina, Corinna;  Kochs, Georg;  Reichl, Udo 

Efficient influenza B virus propagation due to deficient interferon-induced antiviral activity in MDCK cells
In: Vaccine. - Amsterdam : Elsevier, Bd. 29.2011, 41, S. 7125-7129

Bock, A.;  Schulze-Horsel, J.;  Schwarzer, J.;  Rapp, E.;  Genzel, Y.;  Reichl, Udo 

High-density microcarrier cell cultures for influenza virus production
In: Biotechnology progress. - Hoboken, NJ : Wiley, Bd. 27.2011, 1, S. 241-250

Rödig, Jana;  Rapp, Erdmann;  Genzel, Yvonne;  Reichl, Udo 

Impact of different influenza cultivation conditions on HA N-Glycosylation
In: BMC proceedings/ Biomed Central - London: BioMed Central, 2007, 2011, Suppl. 8, P113

Rödig, Jana;  Rapp, Erdmann;  Djeljadini, Suzana;  Lohr, Verena;  Genzel, Yvonne;  Jordan, Ingo;  Sandig, Volker;  Reichl, Udo 

Impact of influenza virus adaptation status on HA N-glycosylation patterns in cell culture-based vaccine production
In: Journal of carbohydrate chemistry - London [u.a.]: Taylor & Francis, 1982, Bd. 30.2011, 4/6, S. 281-290

Riedele, Christian;  Reichl, Udo 

Interspecies effects in a ceftazidime-treated mixed culture of Pseudomonas aeruginosa, Burkholderia cepacia and Staphylococcus aureus: analysis at the single-species level
In: The journal of antimicrobial chemotherapy. - Oxford : Oxford Univ. Press, Bd. 66.2011, 1, S. 138-145

Janke, R.;  Genzel, Y.;  Händel, N.;  Wahl, A.;  Reichl, Udo 

Metabolic adaptation of MDCK cells to different growth conditions - effects on catalytic activities of central metabolic enzymes
In: Biotechnology and bioengineering. - New York, NY [u.a.] : Wiley, Bd. 108.2011, 11, S. 2691-2704

Kuhn, Ramona;  Benndorf, Dirk;  Rapp, Erdmann;  Reichl, Udo;  Palese, Luigi Leonardo;  Pollice, Alfieri 

Metaproteome analysis of sewage from membrane bioreactors
In: Proteomics. - Weinheim : Wiley-Blackwell, Bd. 11.2011, 13, S. 2738-2744

Originalartikel in begutachteter zeitschriftenartiger Reihe

Janke, Robert;  Genzel, Yvonne;  Wetzel, Maria;  Reichl, Udo 

Effect of influenza virus infection on key metabolic enzyme activities in MDCK cells
In: BMC proceedings. - London : BioMed Central, Bd. 5.2011, S. 4

Müller, Thomas;  Dürr, Robert;  Isken, Britta;  Schulze-Horsel, Josef;  Reichl, Udo;  Kienle, Achim 

Population balance modelling of influenza virus replication during vaccine production - influence of apoptosis
In: 21st European Symposium on Computer Aided Process Engineering ; Pt. B. - Amsterdam [u.a.] : Elsevier, S. 1336-1340, 2011 - (Computer-aided chemical engineering; 29) ; Kongress: ESCAPE; 21 (Chalkidiki, Greece) : 2011.05.29-06.01

2010

Originalartikel in begutachteter internationaler Zeitschrift

Lohr, V.;  Genzel, Y.;  Behrendt, I.;  Scharfenberg, K.;  Reichl, Udo 

A new MDCK suspension line cultivated in a fully defined medium in stirred-tank and wave bioreactor
In: Vaccine. - Amsterdam : Elsevier, Bd. 28.2010, 38, S. 6256-6264

Öncül, Alper A.;  Bordás, Robert;  Thévenin, Dominique;  Genzel, Yvonne;  Reichl, Udo 

CFD-Modellierung der Zellkultivierung in Wave-Bioreaktoren
In: Chemie - Ingenieur - Technik . - Weinheim : Wiley-VCH Verl., Bd. 82.2010, 9, S. 1512

Wolff, Michael;  Siewert, Corina;  Lehmann, Sylvia;  Post Hansen, Sara;  Djurup, Rene;  Faber, Rene;  Reichl, Udo 

Capturing of cell culture-derived modified Vaccinia Ankara virus by ion exchange and pseudo-affinity membrane adsorbers
In: Biotechnology and bioengineering . - New York, NY [u.a.] : Wiley, Bd. 105.2010, 4, S. 761-769

Öncül, Alper A.;  Kalmbach, Andreas;  Genzel, Yvonne;  Reichl, Udo;  Thévenin, Dominique 

Characterization of flow conditions in 2 L and 20 L wave bioreactors using computational fluid dynamics
In: Biotechnology progress . - Hoboken, NJ : Wiley, Bd. 26.2010, 1, S. 101-110

Kröber, Tina;  Knöchlein, Anne;  Eisold, Katrin;  Kalbfuß-Zimmermann, Bernd;  Reichl, Udo 

DNA depletion by precipitation in the purification of cell culture-derived influenza vaccines
In: Chemical engineering & technology: industrial chemistry, plant equipment, process engineering, biotechnology / Gesellschaft Deutscher Chemiker ; Deutsche Gesellschaft für Chemisches Apparatewesen, Chemische Technik und Biotechnologie, DECHEMA ; VDI-Gesellschaft Verfahrenstechnik und Chemieingenieurwesen, GVC: industrial chemistry, plant equipment, process engineering, biotechnology - Weinheim: Wiley-VCH, 1987, Bd. 33.2010, 6, S. 941-959

Heynisch, Björn;  Frensing, T.;  Heinze, K.;  Seitz, C.;  Genzel, Y.;  Reichl, Udo 

Differential activation of host cell signalling pathways through infection with two variants of influenza A/Puerto Rico/8/34 (H1N1) in MDCK cells
In: Vaccine . - Amsterdam : Elsevier, ISSN 0264-410x, Bd. 28.2010, 51, S. 8210-8218

Rollié, Sascha;  Lendeckel, Uwe;  Naumann, Michael;  Reichl, Udo;  Sundmacher, Kai 

Dynamics of bionanoparticle targeting in mixtures of human tumour cells by validated population balance modelling
In: Soft matter / publ. by the Royal Society of Chemistry - Cambridge: RSC Publ., 2005, Bd. 6.2010, 6, S. 1203-1216

Kalmbach, Andreas;  Bordás, Róbert;  Öncül, Alper A.;  Thévenin, Dominique;  Genzel, Yvonne;  Reichl, Udo 

Experimental characterization of flow conditions in 2 L and 20 L bioreactors with wave-induced motion
In: Biotechnology progress: a journal of food, pharmaceutical and bioengineering ; a publication of the American Chemical Society and the American Institute of Chemical Engineers - Hoboken, NJ: Wiley, 1985, Bd. 27.2011, 2, S. 402-409

Janke, R.;  Genzel, Y.;  Freund, S.;  Wolff, Michael;  Grammel, H.;  Rühmkorf, C.;  Seidemann, J.;  Wahl, A.;  Reichl, Udo 

Expression, purification, and characterization of a His 6-tagged glycerokinase from Pichia farinosa for enzymatic cycling assays in mammalian cells
In: Journal of biotechnology . - Amsterdam : Elsevier, Bd. 150.2010, 3, S. 396-403

Seitz, Claudius;  Frensing, Timo;  Höper, Dirk;  Kochs, Georg;  Reichl, Udo 

High yields of influenza A virus in MadinDarby canine kidney cells are promoted by an insufficient interferon-induced antiviral state
In: The journal of general virology. - Reading : Society for General Microbiology, Bd. 91.2010, 7, S. 1754-1763

Genzel, Yvonne;  Dietzsch, Christian;  Rapp, Erdmann;  Schwarzer, Jana;  Reichl, Udo 

MDCK and Vero cells for influenza virus vaccine production: a one-to-one comparison up to lab-scale bioreactor cultivation
In: Applied microbiology and biotechnology. - Berlin : Springer, Bd. 88.2010, 2, S. 461-475

Janke, R.;  Genzel, Y.;  Wahl, A.;  Reichl, Udo 

Measurement of key metabolic enzyme activities in mammalian cells using rapid and sensitive microplate-based assays
In: Biotechnology and bioengineering. - New York, NY [u.a.] : Wiley, Bd. 107.2010, 3, S. 566-581

Ritter, Joachim B.;  Wahl, Aljoscha S.;  Freund, Susann;  Genzel, Yvonne;  Reichl, Udo 

Metabolic effects of influenza virus infection in cultured animal cells - intra- and extracellular metabolite profiling
In: BMC systems biology. - London : BioMed Central, Bd. 4.2010, 61, insges. 22 S.

Kuhn, R.;  Benndorf, Dirk;  Rapp, E.;  Reichl, Udo;  Pollice, A.;  Palese, L. L. 

Metaproteomanalyse von Klärschlamm aus Membranbioreaktoren
In: Chemie - Ingenieur - Technik . - Weinheim : Wiley-VCH Verl., Bd. 82.2010, 9, S. 1539

Wolff, Michael W.;  Siewert, Corina;  Post Hansen, Sara;  Faber, Rene;  Reichl, Udo 

Purification of cell culture-derived modified vaccinia ankara virus by pseudo-affinity membrane adsorbers and hydrophobic interaction chromatography
In: Biotechnology and bioengineering. - New York, NY [u.a.] : Wiley, Bd. 107.2010, 2, S. 312-320

Vester, Diana;  Lagoda, Antje;  Hoffmann, Diana;  Seitz, Claudius;  Heldt, Stefan;  Bettenbrock, Katja;  Genzel, Yvonne;  Reichl, Udo 

Real-time RT-qPCR assay for the analysis of human influenza A virus transcription and replication dynamics
In: Journal of virological methods. - Amsterdam : Elsevier, North-Holland Biomed. Press, Bd. 168.2010, 1/2, S. 63-71

Vester, Diana;  Rapp, Erdmann;  Pech, Sabine;  Genzel, Yvonne;  Reichl, Udo 

Virushost cell interactions in vaccine production cell lines infected with different human influenza A virus variants: A proteomic approach
In: Journal of proteomics: official journal of the European Proteomics Association - Amsterdam [u.a.]: Elsevier, 2008, Bd. 73.2010, 9, S. 1656-1669

2009

Artikel in Kongressband

Öncül, Alper A.;  Genzel, Yvonne;  Reichl, Udo;  Thévenin, Dominique 

Flow characterization in wave bioreactors using computational fluid dynamics
In: 21th Meeting of the European Society for Animal Cell Technology \"Cellular Solutions for Clinical Challenges\", ESACT 2009 . - Dublin, insges. 17 S. ; Kongress: ESACT; 21 (Dublin) : 2009.06.07-10

Habilitation

Genzel, Yvonne;  Reichl, Udo;  Seidel-Morgenstern, Andreas 

Upstream processing issues in influenza vaccine production using animal cell technology
In: Magdeburg, Univ., Fak. für Verfahrens- und Systemtechnik, Habil.-Schr., 2009, Getr. Zählung, Ill., graph. Darst., 21 cm

Originalartikel in begutachteter internationaler Zeitschrift

Rapp, Erdmann;  Charvát, Ales;  Beinsen, Alexander;  Plessmann, Uwe;  Reichl, Udo;  Seidel-Morgenstern, Andreas;  Urlaub, Henning;  Abel, Bernd 

Atmospheric pressure free liquid infrared MALDI mass spectrometry - toward a combined ESI/MALDI-liquid chromatography interface
In: Analytical chemistry . - Washington, DC : Soc., Bd. 81.2009, 1, S. 443-452

Schwarzer, Jana;  Rapp, Erdmann;  Hennig, René;  Genzel, Yvonne;  Jordan, Ingo;  Sandig, Volker;  Reichl, Udo 

Glycan analysis in cell culture-based influenza vaccine production - influence of host cell line strain on the glycosylation pattern of viral hemagglutinin
In: Vaccine . - Amsterdam : Elsevier, ISSN 0264-410x, Bd. 27.2009, 32, S. 4325-4336

Schwarzer, Jana;  Rapp, Erdmann;  Hennig, René;  Genzel, Yvonne;  Jordan, Ingo;  Sandig, Volker;  Reichl, Udo 

Glycan analysis in cell culture-based influenza vaccine production: Influence of host cell line and virus strain on the glycosylation pattern of viral hemagglutinin
In: Vaccine . - Amsterdam : Elsevier, ISSN 0264-410x, Bd. 27.2009, 32, S. 4325-4336

Schulze-Horsel, J.;  Schulze, M.;  Agalaridis, G.;  Genzel, Y.;  Reichl, Udo 

Infection dynamics and virus-induced apoptosis in cell culture-based influenza vaccine productionFlow cytometry and mathematical modeling
In: Vaccine . - Amsterdam : Elsevier, ISSN 0264-410x, Bd. 27.2009, 20, S. 2712-2722

Lohr, V.;  Rath, A.;  Genzel, Y.;  Jordan, I.;  Sandig, V.;  Reichl, Udo 

New avian suspension cell lines provide production of influenza virus and MVA in serum-free media - studies on growth, metabolism and virus propagation
In: Vaccine . - Amsterdam : Elsevier, ISSN 0264-410x, Bd. 27.2009, 36, S. 4975-4982

Öncül, Alper A.;  Kalmbach, A.;  Genzel, Y.;  Reichl, Udo;  Thévenin, Dominique 

Numerische und experimentelle Untersuchung der Fließbedingungen in Wave-Bioreaktoren
In: Chemie - Ingenieur - Technik . - Weinheim : Wiley-VCH Verl., Bd. 81.2009, 8, S. 1241

Opitz, Lars;  Hohlweg, Jonas;  Reichl, Udo;  Wolff, Michael W. 

Purification of cell culture-derived influenza virus A/Puerto Rico/8/34 by membrane-based immobilized metal affinity chromatography
In: Journal of virological methods . - Amsterdam : Elsevier, North-Holland Biomed. Press, Bd. 161.2009, 2, S. 312-316

Vester, Diana;  Rapp, Erdmann;  Gade, Dörte;  Genzel, Yvonne;  Reichl, Udo 

Quantitative analysis of cellular proteome alterations in human influenza A virus-infected mammalian cell lines
In: Proteomics . - Weinheim : Wiley VCH, Bd. 9.2009, 12, S. 3316-3327

Opitz, Lars;  Lehmann, Sylvia;  Reichl, Udo;  Wolff, Michael W. 

Sulfated membrane adsorbers for economic pseudo-affinity capture of influenza virus particles
In: Biotechnology and bioengineering . - New York, NY [u.a.] : Wiley, Bd. 103.2009, 6, S. 1144-1154

2008

Originalartikel in begutachteter internationaler Zeitschrift

Pohlscheidt, Michael;  Bödeker, Berthold;  Langer, Uwe;  Apeler, Heiner;  Hörlein, Hans-Dietrich;  Rübsamen-Waigmann, Helga;  Reichl, Udo;  Henzler, Hans-Jürgen 

Auslegungsunterlagen für Bioreaktoren zur Maßstabsvergrößerung eines microcarrierbasierenden Virusproduktionsprozesses
In: Chemie - Ingenieur - Technik . - Weinheim : Wiley-VCH Verl., Bd. 80.2008, 6, S. 821-830

Sidorenko, Yury;  Wahl, Aljoscha;  Dauner, Michael;  Genzel, Yvonne;  Reichl, Udo 

Comparison of metabolic flux distributions for MDCK cell growth in glutamine- and pyruvate-containing media
In: Biotechnology progress . - Hoboken, NJ : Wiley, Bd. 24.2008, 2, S. 311-320

Pohlscheidt, M.;  Langer, U.;  Minuth, T.;  Bödecker, B.;  Apeler, H.;  Hörlein, H.-D.;  Paulsen, D.;  Rübsamen-Waigmann, H.;  Henzler, H.-J.;  Reichl, Udo 

Development and optimisation of a procedure for the production of parapoxvirus ovis by large-scale microcarrier cell culture in a non-animal, non-human and non-plant-derived medium
In: Vaccine . - Amsterdam : Elsevier, ISSN 0264-410x, Bd. 26.2008, 12, S. 1552-1565

Schulze-Horsel, Josef;  Genzel, Yvonne;  Reichl, Udo 

Flow cytometric monitoring of influenza A virus infection in MDCK cells during vaccine production
In: BMC biotechnology . - London : BioMed Central, Bd. 8.2008, 45, insges. 23 S.

Sidorenko, Y.;  Antoniukas, L.;  Schulze-Horsel, J.;  Kremling, A.;  Reichl, Udo 

Mathematical model of growth and heterologous hantavirus protein production of the recombinant yeast saccharomyces cerevisiae
In: Engineering in life sciences . - Weinheim : Wiley-Blackwell, Bd. 8.2008, 4, S. 399-414

Wahl, Aljoscha;  Sidorenko, Yury;  Dauner, Michael;  Genzel, Yvonne;  Reichl, Udo 

Metabolic flux model for an anchorage-dependent MDCK cell line - characteristic growth phases and minimum substrate consumption flux distribution
In: Biotechnology and bioengineering . - New York, NY [u.a.] : Wiley, Bd. 101.2008, 1, S. 135-152

Kalbfuß-Zimmermann, Bernd;  Knöchlein, Anne;  Kröber, Tina;  Reichl, Udo 

Monitoring influenza virus content in vaccine production - precise assays for the quantitation of hemagglutination and neuraminidase activity
In: Biologicals: journal of the International Association of Biological Standardization - Amsterdam [u.a.]: Elsevier, 1990, Bd. 36.2008, 3, S. 145-161

Schwarzer, Jana;  Rapp, Erdmann;  Reichl, Udo 

N-glycan analysis by CGE-LIF - profiling influenza A virus hemagglutinin N-glycosylation during vaccine production
In: Electrophoresis: electrokinetics, fluidics, proteomics - Weinheim: Wiley-VCH, 1980, Bd. 29.2008, 20, S. 4203-4214

Antoniukas, Linas;  Grammel, Hartmut;  Sasnauskas, Kestutis;  Reichl, Udo 

Profiling of external metabolites during production of hantavirus nucleocapsid protein with recombinant saccharomyces cerevisiae
In: Biotechnology letters. - Dordrecht [u.a.] : Kluwer Academic Publ., Bd. 30.2008, 3, S. 415-420

Möhler, Lars;  Bock, Andreas;  Reichl, Udo 

Segregated mathematical model for growth of anchorage-dependent MDCK cells in microcarrier culture
In: Biotechnology progress . - Hoboken, NJ : Wiley, Bd. 24.2008, 1, S. 110-119

Ritter, Joachim B.;  Genzel, Yvonne;  Reichl, Udo 

Simultaneous extraction of several metabolites of energy metabolism and related substances in mammalian cells - optimization using experimental design
In: Analytical biochemistry . - San Diego, Calif. : Elsevier, Bd. 373.2008, 2, S. 349-369

Kalbfuss, Bernd;  Flockerzi, Dietrich;  Seidel-Morgenstern, Andreas;  Reichl, Udo 

Size-exclusion chromatography as a linear transfer system - purification of human influenza virus as an example
In: Journal of chromatography . - Amsterdam [u.a.] : Elsevier, Bd. 873.2008, 1, S. 102-112

Sidorenko, Y.;  Schulze-Horsel, J.;  Voigt, Andreas;  Reichl, Udo;  Kienle, Achim 

Stochastic population balance modeling of influenza virus replication in vaccine production processes
In: Chemical engineering science. - Amsterdam : Elsevier, Bd. 63.2008, 1, S. 157-169

Sidorenko, Y.;  Voigt, Andreas;  Schulze-Horsel, J.;  Reichl, Udo;  Kienle, Achim 

Stochastic population balance modeling of influenza virus replication in vaccine production processes. II. detailed description of the replication mechanism
In: Chemical engineering science. - Amsterdam : Elsevier, Bd. 63.2008, 8, S. 2299-2304

Originalartikel in begutachteter zeitschriftenartiger Reihe

Müller, Thomas;  Schulze-Horsel, Josef;  Sidorenko, Yury;  Reichl, Udo;  Kienle, Achim 

Population balance modeling of influenza virus replication in MDCK cells during vaccine production
In: 18th European Symposium on Computer Aided Process Engineering. - Amsterdam [u.a.] : Elsevier, S. 133-138, 2008 - (Computer-aided chemical engineering; 25) ; Kongress: ESCAPE; 18 (Lyon) : 2008.06.01-04

2007

Buchbeitrag

Bock, A.;  Reichl, Udo 

Closed loop control of perfusion systems in high-density cell culture
In: Cell technology for cell products: proceedings of the 19th ESACT meeting, Harrogate, UK, June 5-8, 2005 / Hrsg. Rodney Smith: proceedings of the 19th ESACT meeting, Harrogate, UK, June 5-8, 2005 - Dordrecht: Springer Netherland . - 2007, S. 549-551 ; Kongress: European Society for Animal Cell Technology meeting 19 (Harrogate : 2005.06.05-08)

Reichl, Udo;  Sidorenko, Yury 

Dynamics of virus-host cell interaction
In: Bioinformatics - from genomes to therapies ; Vol. 2:Getting at the inner workings: molecular interactions - Weinheim: WILEY-VCH . - 2007, S. 861-898

Genzel, Yvonne;  Schulze-Horsel, Josef;  Möhler, Lars;  Sidorenko, Yury;  Reichl, Udo 

Influenza vaccine - challanges in mammalian cell culture technology
In: Cell technology for cell products: proceedings of the 19th ESACT meeting, Harrogate, UK, June 5-8, 2005 / Hrsg. Rodney Smith: proceedings of the 19th ESACT meeting, Harrogate, UK, June 5-8, 2005 - Dordrecht: Springer Netherland . - 2007, S. 503-508 ; Kongress: European Society for Animal Cell Technology meeting 19 (Harrogate : 2005.06.05-08)

Schulze-Horsel, Josef;  Genzel, Yvonne;  Reichl, Udo 

Monitoring cell physiology in influenza vaccine production by flow cytometry
In: Cell technology for cell products: proceedings of the 19th ESACT meeting, Harrogate, UK, June 5-8, 2005 / Hrsg. Rodney Smith: proceedings of the 19th ESACT meeting, Harrogate, UK, June 5-8, 2005 - Dordrecht: Springer Netherland . - 2007, S. 531-533 ; Kongress: European Society for Animal Cell Technology meeting 19 (Harrogate : 2005.06.05-08)

Ritter, Joachim B.;  Genzel, Yvonne;  Reichl, Udo 

Monitoring of extracellular TCA cycle intermediates in mammalian cell culture
In: Cell technology for cell products: proceedings of the 19th ESACT meeting, Harrogate, UK, June 5-8, 2005 / Hrsg. Rodney Smith: proceedings of the 19th ESACT meeting, Harrogate, UK, June 5-8, 2005 - Dordrecht: Springer Netherland . - 2007, S. 603-605 ; Kongress: European Society for Animal Cell Technology meeting 19 (Harrogate : 2005.06.05-08)

Genzel, Yvonne;  Fischer, Marlies;  Olmer, Ruth Maria;  Schäfer, Bastian;  Best, Claudia;  König, Susanne;  Hundt, Boris;  Reichl, Udo 

Serum-free influenza vaccine production with MDCK cells in wave-bioreactor and 5L-stirred tank bioreactor
In: Cell technology for cell products: proceedings of the 19th ESACT meeting, Harrogate, UK, June 5-8, 2005 / Hrsg. Rodney Smith: proceedings of the 19th ESACT meeting, Harrogate, UK, June 5-8, 2005 - Dordrecht: Springer Netherland . - 2007, S. 563-565 ; Kongress: European Society for Animal Cell Technology meeting 19 (Harrogate : 2005.06.05-08)

Pohlscheidt, M.;  Langer, U.;  Bödeker, B.;  Paulsen, D.;  Rübsamen-Waigmann, H.;  Reichl, Udo;  Henzler, H. J.;  Apeler, H. 

Strategies for large scale production of Parapoxvirus Ovis NZ-2
In: Cell technology for cell products: proceedings of the 19th ESACT meeting, Harrogate, UK, June 5-8, 2005 / Hrsg. Rodney Smith: proceedings of the 19th ESACT meeting, Harrogate, UK, June 5-8, 2005 - Dordrecht: Springer Netherland . - 2007, S. 707-710 ; Kongress: European Society for Animal Cell Technology meeting 19 (Harrogate : 2005.06.05-08)

Genzel, Yvonne;  Reichl, Udo 

Vaccine production - state of the art and future needs in upstream processing
In: Animal cell biotechnology: methods and protocols / ed. by Ralf Pörtner: methods and protocols - Totowa, N.J.: Humana Press . - 2007, S. 457-473 - (Methods in biotechnology; 24)

Originalartikel in begutachteter internationaler Zeitschrift

Schmidt, Julia;  König, Brigitte;  Reichl, Udo 

Characterization of a three bacteria mixed culture in a chemostat - evaluation and application of a quantitative terminal-restriction fragment length polymorphism (T-RFLP) analysis for absolute and species specific cell enumeration
In: Biotechnology and bioengineering . - New York, NY [u.a.] : Wiley, Bd. 96.2007, 4, S. 738-756

Nischang, Ivo;  Reichl, Udo;  Seidel-Morgenstern, Andreas;  Tallarek, Ulrich 

Concentration polarization and nonequilibrium electroosmotic slip in dense multiparticle systems
In: Langmuir: the ACS journal of surfaces and colloids / American Chemical Society: the ACS journal of surfaces and colloids - Washington, DC: ACS Publ., Bd. 23 (2007), 18, S. 9271-9281

Kalbfuss, Bernd;  Wolff, Michael;  Geisler, Liane;  Tappe, Alexander;  Wickramasinghe, Ranil;  Thom, Volkmar;  Reichl, Udo 

Direct capture of influenza A virus from cell culture supernatant with Sartobind anion-exchange membrane adsorbers
In: Journal of membrane science - Amsterdam: Elsevier, Bd. 299 (2007), 1/2, S. 251-260

Hundt, B.;  Best, Claudia;  Schlawin, N.;  Kaßner, H.;  Genzel, Y.;  Reichl, Udo 

Establishment of a mink enteritis vaccine production process in stirred-tank reactor and wave bioreactor microcarrier culture in 1-10 L scale
In: Vaccine - Amsterdam: Elsevier, Bd. 25 (2007), 20, S. 3987-3995

Bandaru, Krishna S. V. S. R.;  Kessler, Lars Christian;  Wolf, Michael W.;  Reichl, Udo;  Seidel-Morgenstern, Andreas;  Pushpavanam, Subramaniam 

Hydrodynamic characteristics and expansion behavior of beds containing single and binary mixtures of particles
In: Industrial & engineering chemistry research: I & EC research ; a publication of the American Chemical Society for applied chemistry & chemical engineering - Washington, DC: ACS Publ., Bd. 46 (2007), 13, S. 4686-4694

Opitz, Lars;  Lehmann, Sylvia;  Zimmermann, Anke;  Reichl, Udo;  Wolf, Michael W. 

Impact of adsorbents selection on capture efficiency of cell culture derived human influenza viruses
In: Journal of biotechnology - Amsterdam: Elsevier, Bd. 131 (2007), 3, S. 309-317

Opitz, Lars;  Salaklang, Jatuporn;  Büttner, Hermann;  Reichl, Udo;  Wolff, Michael W. 

Lectin-affinity chromatography for downstream processing of MDCK cell culture derived human influenza A viruses
In: Vaccine - Amsterdam: Elsevier, Bd. 25 (2007), 5, S. 939-947

Antoniukas, Linas;  Grammel, Hartmut;  Sasnauskas, Kestutis;  Reichl, Udo 

Profiling of external metabolites during production of hantavirus nucleocapsid protein with recombinant saccharomyces cerevisiae
In: Biotechnology letters - Dordrecht [u.a.]: Springer Science + Business Media B.V . - 2007, insges. 6 S.

2006

Originalartikel in begutachteter internationaler Zeitschrift

Heßeler, Julia;  Schmidt, Julia K.;  Reichl, Udo;  Flockerzi, Dietrich 

Coexistence in the chemostat as a result of metabolic by-products
In: Journal of mathematical biology - Berlin: Springer, Bd. 53.2006, 4, S. 556-584

Kalbfuss, Bernd;  Genzel, Yvonne;  Wolff, Michael;  Zimmermann, Anke;  Morenweiser, Robert;  Reichl, Udo 

Harvesting and concentration of human influenza - a virus produced in serum-free mammalian cell culture for the production of vaccines
In: Biotechnology and bioengineering - New York, NY [u.a.]: Wiley, Bd. 97.2007, 1, S. 73-85, 2006

Ritter, Joachim B.;  Genzel, Yvonne;  Reichl, Udo 

High-performance anion-exchange chromatography using on-line electrolytic eluent generation for the determination of more than 25 intermediates from energy metabolism of mammalian cells in culture
In: Journal of chromatography / B - New York, NY [u.a.]: Science Direct, Bd. 843.2006, 2, S. 216-226

Kalbfuss, Bernd;  Wolff, Michael;  Morenweiser, Robert;  Reichl, Udo 

Purification of cell culture-derived human influenza a virius by size-exclusion and anion-exchange chromatography
In: Biotechnology and bioengineering - New York, NY [u.a.]: Wiley, Bd. 96.2007, 5, S. 932-944, 2006

2005

Buchbeitrag

Genzel, Y. (ext.);  Alt, R. (ext.);  Reichl, Udo 

Glutamine-free media for vaccine production processes.
In: Godia, Francesc (Hrsg.) ; Fussenegger, Martin (Hrsg.): Animal cell technology meets genomics ( 18th ESACT meeting Granada, Spain, May 11 - 14 2003). - proceedings. Dordrecht : Springer, 2005, S. 767 - 770 (ESACT 18)

Hundt, Boris;  Schaenzler, A. (ext.);  Reichl, Udo 

Serum free cultivation of primary chicken embryo fibroblasts in microcarrier systems for vaccine production.
In: Godia, Francesc (Hrsg.) ; Fussenegger, Martin (Hrsg.): Animal cell technology meets genomics ( 18th ESACT meeting Granada, Spain, May 11 - 14 2003). - proceedings. Dordrecht : Springer, 2005, S. 771 - 774 (ESACT 18)

Originalartikel in begutachteter internationaler Zeitschrift

Nayak, Deba Prasad (ext.);  Lehmann, Sylvia (ext.);  Reichl, Udo 

Downstream processing of MDCK cell-derived equine influenza virus.
In: Journal of Chromatography B [Amsterdam] 823(2005), S. 75 - 81

Moehler, Lars;  Flockerzi, Dietrich (ext.);  Sann, Heiner (ext.);  Reichl, Udo 

Mathematical model of influenza a virus production in large-scale microcarrier culture.
In: Biotechnology and bioengineering [New York, NY] 90(2005), Nr. 4, S. 46 - 58

Genzel, Yvonne (ext.);  Ritter, Joachim B. (ext.);  Koenig, Susanne (ext.);  Alt, Ruediger (ext.);  Reichl, Udo 

Substitution of glutamine by pyruvate to reduce ammonia formation and groth inhibition of mammalian cells.
In: Biotechnology progress [New York, NY] 21(2005), S. 58 - 69

Wickramasinghe, S.R. (ext.);  Kalbfuss, B. (ext.);  Zimmermann, A. (ext.);  Thom, V. (ext.);  Reichl, Udo 

Tangential flow microfiltration and ultrafiltration for human influenza a virus concentration and purification.
In: Biotechnology and bioengineering [New York, NY] 92(2005), Nr. 2, S. 199 - 208

2004

Artikel in Kongressband

Sidorenko, Y. (ext.);  Reichl, Udo 

A mathematical model for the replication of influenza a virus in MDCK cells.
In: BioPerspectives 2004 : mit 22. DECHEMA-Jahrestagung der Biotechnologen (Wiesbaden, 4. - 6. Mai 2004). - Tagungshandbuch. Frankfurt am Main, 2004, S. 82

Originalartikel in begutachteter internationaler Zeitschrift

Genzel, Yvonne (ext.);  Koenig, Susanne (ext.);  Reichl, Udo 

Amino acid analysis in mammalian cell culture media containing serum and high glucose concentrations by anion exchange chromatography and integrated pulsed amperometric detecion.
In: Analytical biochemistry [New York, NY] 335(2004), S. 119 - 125

Genzel, Y. (ext.);  Behrendt, I. (ext.);  Koenig, S. (ext.);  Sann, H. (ext.);  Reichl, Udo 

Metabolism of MDCK cells during cell growth and influenza virus production in large-scale microcarrier culture.
In: Vaccine [Amsterdam] 22(2004), S. 2202 - 2208

Nayak, Deba Prasad (ext.);  Reichl, Udo 

Neuraminidase activity assays for monitoring MDCK cell culture derived influenza virus.
In: Journal of virological methods [Amsterdam] 122(2004), S. 9 - 15

Sidorenko, Y. (ext.);  Reichl, Udo 

Structured model of influenza virus replication in MDCK cells.
In: Biotechnology and bioengineering [New York, NY] 88(2004), Nr. 1, S. 1 - 14

2003

Artikel in Kongressband

Reichl, Udo;  Genzel, Yvonne (ext.);  Moehler, Lars;  Sydorenko, I. (ext.);  Sann, H. (ext.) 

Animal cell cultures for the production of viral vaccines.
In: VDI-Gesellschaft (Veranst.) ; DECHEMA e. V. (Veranst.): GVC/DECHEMA : Vortrags- und Diskussionstagung (\"Zellkulturen : vom biologischen System zum Produktionsprozess\" Bad Dürkheim, 26. bis 28. Mai 2003). - Tagungsband. Bad Dürkheim, 2003, S. 32 - 35

Originalartikel in begutachteter internationaler Zeitschrift

Tallarek, Ulrich;  Rapp, Erdmann (ext.);  Sann, Heiner (ext.);  Reichl, Udo;  Seidel Morgenstern, Andreas 

Quantitative study of electrokinetic transport in porous media by confocal laser scanning microscopy.
In: Langmuir [Washington, DC] 19(2003), Nr. 11, S. 4527 - 4531

2002

Originalartikel in begutachteter internationaler Zeitschrift

Trotha, Rene;  Reichl, Udo;  Thies, Frank;  Sperling, Danuta;  Koenig, Wolfgang;  Koenig, Brigitte 

Adaption of a fragment analysis technique to an automated high-throughput multicapillary electrophoresis device for the precise qualitative and quantitative characterization of microbial communities.
In: Electrophoresis [Weinheim] 23(2002), S. 1070 - 1079

2001

Buchbeitrag

Genzel, Yvonne (ext.);  Voges, Lars;  Reichl, Udo 

Development of bioprocess concepts on vaccine production : influenza virus as an example.
In: Lindner-Olsson, E. (Hrsg.) ; Chatzissavidou, N. (Hrsg.) ; Lüllau, E. (Hrsg.): Animal cell technology : from target to market (17th ESACT meeting, Tylösand, Sweden, June 10-14, 2001). - proceedings. Dordrecht : Kluwer, 2001, S. 344 - 346

Originalartikel in begutachteter nationaler Zeitschrift

Kremling, Andreas (ext.);  Bettenbrock, Katja (ext.);  Stelling, Joerg (ext.);  Reichl, Udo;  Gilles, Ernst-Dieter (ext.) 

Systemorientierte Bioprozesstechnik : interdisziplinäre Forschung in Biologie, System- und Computerwissenschaften.
In: Magdeburger Wissenschaftsjournal [Magdeburg] 6(2001), Nr. 1/2, S. 29 - 36

2000

Buchbeitrag

Reichl, Udo 

ISCOM vaccines : antigen production and downstream processing.
In: Brunner, Herwig (Hrsg.): Biochemical engineering (4th International congress Stuttgart 17 and 18 February, 2000). - proceedings. Stuttgart : Fraunhofer-IRB-Verl., 2000, S. 314 - 318

Vita
1980 - 1987Studium Biologie, Diplom, Universität Saarbrücken
1991Promotion am Institut für Systemdynamik der Universität Stuttgart, Abschluss: Doktoringenieur (Dr.-Ing.)
1991 - 1992Wissenschaftlicher Mitarbeiter, Biotechnologie, University of British Columbia, Vancouver, Kanada
1992 - 1993Wissenschaftlicher Mitarbeiter, Biotechnologie, Institut für Systemdynamik und Regelungstechnik, Universität Stuttgart
1993Projektleiter ¿Mikrocarrier¿, Pitman-Moore GmbH, Burgwedel
1993 - 1996Abteilungsleiter Virusproduktion, Pitman-Moore GmbH, Burgwedel
1996 - 1999Stellvertretender Herstellungsleiter, Mallinckrodt Vet GmbH / Essex Animal Health, Burgwedel
seit 1999o. Professor für Bioprozesstechnik, Otto-von-Guericke-Universität, Magdeburg
seit 2000Wissenschaftliches Mitglied der Max-Planck-Gesellschaft zur Förderung der Wissenschaften e.V.
seit 2000Direktor am Max-Planck-Institut für Dynamik komplexer technischer Systeme, Abteilung System- und signalorientierte Bioprozesstechnik, Magdeburg
2003 - 2004Geschäftsführender Leiter des Instituts für Verfahrenstechnik, Otto-von-Guericke-Universität, Magdeburg
2005 - 2006Geschäftsführender Direktor am Max-Planck-Institut für Dynamik komplexer technischer Systeme, Magdeburg
seit 2005Mitglied der Perspektivenkommission der CPTS der Max-Planck-Gesellschaft
2007 - 2013Sprecher der IMPRS ("International Max Planck Research School for Analysis, Design and Optimization in Chemical and Biochemical Process Engineering"), Magdeburg
2009 - 2010Geschäftsführender Leiter des Instituts für Verfahrenstechnik, Otto-von-Guericke-Universität, Magdeburg
2011 - 2012Geschäftsführender Direktor am Max-Planck-Institut für Dynamik komplexer technischer Systeme, Magdeburg
2017 - 2018Geschäftsführender Leiter des Instituts für Verfahrenstechnik, Otto-von-Guericke-Universität, Magdeburg
2019 - 2020Geschäftsführender Direktor am Max-Planck-Institut für Dynamik komplexer technischer Systeme, Magdeburg

Letzte Änderung: 01.09.2021 - Ansprechpartner: Webmaster