Publikationen
2024
Begutachteter Zeitschriftenartikel
Model-based optimization of cell-free enzyme cascades exemplified for the production of GDP-fucose
Huber, Nicolas; Alcalá-Orozco, Edgar Alberto; Rexer, Thomas; Reichl, Udo; Klamt, Steffen
In: Metabolic engineering - Orlando, Fla. : Academic Press, Bd. 81 (2024), S. 10-25
Begutachteter Zeitschriftenartikel
Production of recombinant vesicular stomatitis virus-based vectors by tangential flow depth filtration
Göbel, Sven; Pelz, Lars; Silva, Cristina A. T.; Brühlmann, Béla; Hill, Charles; Altomonte, Jennifer; Kamen, Amine; Reichl, Udo; Genzel, Yvonne
In: Applied microbiology and biotechnology - Berlin : Springer, Bd. 108 (2024), Artikel 240, insges. 18 S.
Begutachteter Zeitschriftenartikel
Breakdown of hardly degradable carbohydrates (lignocellulose) in a two-stage anaerobic digestion plant is favored in the main fermenter
Heyer, Robert; Hellwig, Patrick; Maus, Irena; Walke, Danile; Schlüter, Andreas; Hassa, Julia; Sczyrba, Alexander; Tubbesing, Tom; Klocke, Michael; Mächtig, Torsten; Schallert, Kay; Seick, Ingolf; Reichl, Udo; Benndorf, Dirk
In: Water research - Amsterdam [u.a.] : Elsevier Science, Bd. 250 (2024), Artikel 121020, insges. 11 S.
Begutachteter Zeitschriftenartikel
From single-cell cloning to high-yield influenza virus production - implementing advanced technologies in vaccine process development
Zinnecker, Tilia; Badri, Najd; Araujo, Diogo; Thiele, Kristin; Reichl, Udo; Genzel, Yvonne
In: Engineering in life sciences - Weinheim : Wiley-VCH . - 2024, insges. 14 S. [Online first]
2023
Abstract
Adjuvanted SARS-CoV-2 spike protein vaccination with altered glycosylation elicits improved TH1 humoral and cellular immunity in mice
Rudert, J.; Bälkner, M.; Juarez-Osorio, M.; Rexer, T.; Reichl, Udo; Jacobsen, H.; Metzdorf, K.; Bruder, D.; Volckmar, J.
In: European journal of immunology - Weinheim : Wiley-VCH, Bd. 53 (2023), Heft S2, S. 358, Artikel P376 [Konferenz: Joint Conference of the Société Française d'Immunologie (SFI) and the Deutsche Gesellschaft für Immunologie (DGfI), Strasbourg, France, 26-29 September 2023]
Buchbeitrag
Upstream processing for viral vaccines - process intensification
Göbel, Sven; Pelz, Lars; Reichl, Udo; Genzel, Yvonne
In: Bioprocessing of viral vaccines , First edition - Abgingdon : Taylor & Francis ; Kamen, Amine . - 2023, S. 137-173
Buchbeitrag
Upstream processing for viral vaccines - general aspects
Pelz, Lars; Göbel, Sven; Jaen, Karim; Reichl, Udo; Genzel, Yvonne
In: Bioprocessing of viral vaccines , First edition - Abgingdon : Taylor & Francis ; Kamen, Amine . - 2023, S. 79-135
Begutachteter Zeitschriftenartikel
Removable Ddes - the missing link for in-depth N-glycan analysis via multi-method approaches
Cajic, Samanta; Hennig, René; Grote, Valerian; Reichl, Udo; Rapp, Erdmann
In: Engineering - Beijing : Engineering Sciences Press., Bd. 26 (2023), S. 132-150
Begutachteter Zeitschriftenartikel
Cell-free N-glycosylation of peptides using synthetic lipid-linked hybrid and complex N-glycans
Wenzel, Lisa; Hoffmann, Marcus; Rapp, Erdmann; Rexer, Thomas F. T.; Reichl, Udo
In: Frontiers in molecular biosciences - Lausanne : Frontiers, Bd. 10 (2023), insges. 11 S.
Begutachteter Zeitschriftenartikel
A cell-free multi-enzyme cascade reaction for the synthesis of CDP-glycerol
Alcalá-Orozco, E. Alberto; Grote, Valerian; Fiebig, Timm; Klamt, Steffen; Reichl, Udo; Rexer, Thomas
In: ChemBioChem - Weinheim : Wiley-VCH . - 2023, Artikel e202300463 [Early view]
Begutachteter Zeitschriftenartikel
Characterization of a quail suspension cell line for production of a fusogenic oncolytic virus
Göbel, Sven; Jaén, Karim E.; Fernandes, Rita P.; Reiter, Manfred; Altomonte, Jennifer; Reichl, Udo; Genzel, Yvonne
In: Biotechnology & bioengineering - New York, NY [u.a.] : Wiley . - 2023, insges. 12 S. [Early view]
Begutachteter Zeitschriftenartikel
Broad-spectrum antiviral activity of influenza A Defective Interfering Particles against respiratory syncytial, yellow fever, and Zika virus replication in vitro
Pelz, Lars; Piagnani, Elena; Marsall, Patrick; Wynserski, Nancy; Hein, Marc Dominique; Marichal-Gallardo, Pavel; Kupke, Sascha Young; Reichl, Udo
In: Viruses - Basel : MDPI, Bd. 15 (2023), Heft 9, Artikel 1872, insges. 17 S.
Begutachteter Zeitschriftenartikel
Production of retroviral vectors in continuous high cell density culture
Hein, Marc D.; Kazenmaier, Daniel; van Heuvel, Yasemin; Dogra, Tanya; Cattaneo, Maurizio; Kupke, Sascha Y.; Stitz, Jörn; Genzel, Yvonne; Reichl, Udo
In: Applied microbiology and biotechnology - Berlin : Springer, Bd. 107 (2023), S. 5947-5961
Begutachteter Zeitschriftenartikel
Cell-free biosynthesis meets dynamic optimization and control - a fed-batch framework
Espinel-Ríos, Sebastián; Huber, Nicolas; Alcalá-Orozco, Edgar Alberto; Morabito, Bruno; Rexer, Thomas F. T.; Reichl, Udo; Klamt, Steffen; Findeisen, Rolf
In: IFAC-PapersOnLine / Internationale Förderung für Automatische Lenkung - Frankfurt : Elsevier, Bd. 55 (2022), Heft 23, S. 92-97
Begutachteter Zeitschriftenartikel
Reliable N-glycan analysis - removal of frequently occurring oligosaccharide impurities by enzymatic degradation
Burock, Robert; Cajic, Samanta; Henning, René; Buettner, Falk, F. R.; Reichl, Udo; Rapp, Erdmann
In: Molecules - Basel : MDPI, Bd. 28 (2023), Heft 4, Artikel 1843, insges. 19 S.
Begutachteter Zeitschriftenartikel
Degradation kinetics of lignocellulolytic enzymes in a biogas reactor using quantitative mass spectrometry
Küchler, Jan; Willenbücher, Katharina; Reiß, Elisabeth; Nuß, Lea; Conrady, Marius; Ramm, Patrice; Schimpf, Ulrike; Reichl, Udo; Szewzyk, Ulrich; Benndorf, Dirk
In: Fermentation - Basel : MDPI, Bd. 9 (2023), Heft 1, Artikel 67, 1 Online-Ressource (12 Seiten)
Begutachteter Zeitschriftenartikel
Process intensification strategies toward cell culture-based high-yield production of a fusogenic oncolytic virus
Göbel, Sven; Jaén, Karim E.; Dorn, Marie; Neumeyer, Victoria; Jordan, Ingo; Sandig, Volker; Reichl, Udo; Altomonte, Jennifer; Genzel, Yvonne
In: Biotechnology & bioengineering - New York, NY [u.a.] : Wiley . - 2023, insges. 19 S.
Begutachteter Zeitschriftenartikel
Generation of "OP7 chimera" defective interfering influenza A particle preparations free of infectious virus that show antiviral efficacy in mice
Dogra, Tanya; Pelz, Lars; Boehme, Julia D.; Kuechler, Jan; Kershaw, Olivia; Marichal-Gallardo, Pável Alejandro; Baelkner, Maike; Hein, Marc Dominique; Gruber, Achim; Benndorf, Dirk; Genzel, Yvonne; Bruder, Dunja; Kupke, Sascha Young; Reichl, Udo
In: Scientific reports - [London] : Macmillan Publishers Limited, part of Springer Nature, Bd. 13 (2023), Artikel 20936, insges. 13 S.
2022
Artikel in Zeitschrift
Discovering biomarkers for non-alcoholic steatohepatitis patients with and without hepatocellular carcinoma using fecal metaproteomics
Sydor, Svenja; Dandyk, Christian; Schwerdt, Johannes; Manka, Paul; Benndorf, Dirk; Lehmann, Theresa; Schallert, Kay; Wolf, Maximilian; Reichl, Udo; Canbay, Ali E.; Bechmann, Lars P.; Heyer, Robert
In: International journal of molecular sciences - Basel : Molecular Diversity Preservation International, Bd. 23 (2022), Heft 16, Artikel 8841, insges. 14 S.
Aufsatz
Absolute quantification of viral proteins during single-round replication of MDCK suspension cells
Küchler, Jan; Püttker, Sebastian; Lahmann, Patrick; Genzel, Yvonne; Kupke, Sascha; Benndorf, Dirk; Reichl, Udo
In: Journal of proteomics - New York, NY [u.a.] : Elsevier, Bd. 259 (2022), Artikel 104544, insges. 10 S.
Begutachteter Zeitschriftenartikel
High-titer hepatitis C virus production in a scalable single-use high cell density bioreactor
Offersgaard, Anna; Duarte Hernandez, Carlos Rene; Pihl, Anne Finne; Venkatesan, Nadini Prabhakar; Krarup, Henrik; Lin, Xiangliang; Reichl, Udo; Bukh, Jens; Genzel, Yvonnne; Gottwein, Judith Margarete
In: Vaccines - Basel : MDPI, Bd. 10 (2022), Heft 2, Artikel 249, insges. 24 S.
Begutachteter Zeitschriftenartikel
Adaptation of a microbial community to demand-oriented biological methanation
Khesali Aghtaei, Hoda; Püttker, Sebastian; Maus, Irena; Heyer, Robert; Huang, Liren; Sczyrba, Alexander; Reichl, Udo; Benndorf, Dirk
In: Biotechnology for biofuels and bioproducts - London : BioMed Central , 2022, Bd. 15 (2022), Heft 1, Artikel 125, 1 Online-Ressource (19 Seiten)
Begutachteter Zeitschriftenartikel
Human 3D airway tissue models for real-time microscopy - visualizing respiratory virus spreading
Möckel, Marion; Baldok, Nino; Walles, Thorsten; Hartig, Roland; Müller, Andreas Johann; Reichl, Udo; Genzel, Yvonne; Walles, Heike; Wiese-Rischke, Cornelia
In: Cells - Basel : MDPI, Bd. 11 (2022), Heft 22, Artikel 3634, insges. 21 S.
Begutachteter Zeitschriftenartikel
Cell-line screening and process development for a fusogenic oncolytic virus in small-scale suspension cultures
Göbel, Sven; Kortum, Fabian; Chavez, Karim Jaén; Jordan, Ingo; Sandig, Volker; Reichl, Udo; Altomonte, Jennifer; Genzel, Yvonne
In: Applied microbiology and biotechnology - Berlin : Springer, Bd. 106 (2022), Heft 13/16, S. 4945-4961
Begutachteter Zeitschriftenartikel
Impact of influenza A virus infection on growth and metabolism of suspension MDCK cells using a dynamic model
Ramos, João Rodrigues Correia; Bissinger, Thomas; Genzel, Yvonne; Reichl, Udo
In: Metabolites - Basel : MDPI, Bd. 12 (2022), Heft 3, Artikel 239, insges. 27 S.
Dissertation
Development of chromatography-based purification processes for cell culture-derived influenza virus particles
Weigel, Thomas; Reichl, Udo
In: Magdeburg: Universitätsbibliothek, Dissertation Otto-von-Guericke-Universität Magdeburg, Fakultät für Verfahrens- und Systemtechnik 2022, 1 Online-Ressource (XXII, 145 Seiten, 2,22 MB) [Literaturverzeichnis: Seite 119-133]
Dissertation
Cell culture-based production of influenza A virus-derived defective interfering particles
Hein, Marc Dominique; Reichl, Udo
In: Magdeburg: Universitätsbibliothek, Dissertation Otto-von-Guericke-Universität Magdeburg, Fakultät für Verfahrens- und Systemtechnik 2022, 1 Online-Ressource (XV, 98, XVII-L Seiten, 5,1 MB) [Literaturverzeichnis: Seite XX-XXXVII]
Dissertation
Mathematical models of influenza A virus infection - multiplicity of infection and its impact on co-infection and virus production
Rüdiger, Daniel; Tsotsas, Evangelos; Reichl, Udo
In: Magdeburg: Universitätsbibliothek, 2022, 1 Online-Ressource (XVIII, 179 Seiten, 8,16 MB), Illustrationen
2021
Aufsatz
Tracking changes in adaptation to suspension growth for MDCK cells: cell growth correlates with levels of metabolites, enzymes and proteins
Pech, Sabine; Rehberg, Markus; Janke, Robert; Benndorf, Dirk; Genzel, Yvonne; Muth, Thilo; Sickmann, Albert; Rapp, Erdmann; Reichl, Udo
In: Applied microbiology and biotechnology - Berlin : Springer, Bd. 105 (2021), S. 1861-1874
Aufsatz
Fecal metaproteomics reveals reduced gut inflammation and changed microbial metabolism following lifestyle-induced weight loss
Biemann, Ronald; Buß, Enrico; Benndorf, Dirk; Lehmann, Theresa; Schallert, Kay; Püttker, Sebastian; Reichl, Udo; Isermann, Berend; Schneider, Jochen; Saake, Gunter; Heyer, Robert
In: Biomolecules - Basel : MDPI - Vol.11.2021, 5, 726, insgesamt 13 Seiten
Buchbeitrag
Preface
Rapp, Erdmann; Reichl, Udo
In: Advances in Glycobiotechnology - Cham: Springer International Publishing; Rapp, Erdmann . - 2021, S. v-vi
Buchbeitrag
Correction to: Animal Cell Expression Systems
Butler, M.; Reichl, Udo
In: Advances in Glycobiotechnology - Cham: Springer International Publishing; Rapp, Erdmann . - 2021, S. 459-461
Begutachteter Zeitschriftenartikel
SARS-CoV-2 production in a scalable high cell density bioreactor
Offersgaard, Anna; Duarte Hernandez, Carlos Rene; Pihl, Anne Finne; Costa, Rui; Venkatesan, Nandine Prabhakar; Lin, Xiangliang; Pham, Long Van; Feng, Shan; Fahnøe, Ulrik; Scheel, Troels Kasper Høyer; Ramirez, Santseharay; Reichl, Udo; Bukh, Jens; Genzel, Yvonne; Gottwein, Judith Margarete
In: Vaccines - Basel: MDPI, Bd. 9 (2021), 7
Begutachteter Zeitschriftenartikel
A high cell density perfusion process for Modified Vaccinia virus Ankara production - process integration with inline DNA digestion and cost analysis
Gränicher, Gwendal; Babakhani, Masoud; Göbel, Sven; Jordan, Ingo; Marichal-Gallardo, Pavel; Genzel, Yvonne; Reichl, Udo
In: Biotechnology & bioengineering - New York, NY [u.a.]: Wiley . - 2021, insges. 15 S.
Begutachteter Zeitschriftenartikel
Cell-free glycoengineering of the recombinant SARS-CoV-2 spike glycoprotein
Ruhnau, Johannes; Grote, Valerian; Juarez-Osorio, Mariana; Bruder, Dunja; Mahour, Reza; Rapp, Erdmann; Rexer, Thomas F. T.; Reichl, Udo
In: Frontiers in Bioengineering and Biotechnology - Lausanne: Frontiers Media, 2013, Bd. 9 (2021), insges. 10 S.
Begutachteter Zeitschriftenartikel
Cell culture-based production of defective interfering influenza A virus particles in perfusion mode using an alternating tangential flow filtration system
Hein, Marc D.; Chawla, Anshika; Cattaneo, Maurizio; Kupke, Sascha Y.; Genzel, Yvonne; Reichl, Udo
In: Applied microbiology and biotechnology - Berlin: Springer, Bd. 105 (2021), S. 72517264
Begutachteter Zeitschriftenartikel
Multiscale model of defective interfering particle replication for influenza A virus infection in animal cell culture
Rüdiger, Daniel; Pelz, Lars; Hein, Marc D.; Kupke, Sascha Y.; Reichl, Udo
In: PLoS Computational Biology/ Public Library of Science - San Francisco, Calif.: Public Library of Science, Bd. 17 (2021), 9, insges. 28 S.
Begutachteter Zeitschriftenartikel
Combining functional metagenomics and glycoanalytics to identify enzymes that facilitate structural characterization of sulfated N-glycans
Chuzel, Léa; Fossa, Samantha L.; Boisvert, Madison L.; Cajic, Samanta; Heenig, René; Ganatra, Mehul B.; Reichl, Udo; Rapp, Erdmann; Taron, Christopher H.
In: Microbial cell factories - London: Biomed Central, Bd. 20 (2021), S. 1-17
Begutachteter Zeitschriftenartikel
Integrated cycles for urban biomass as a strategy to promote a CO2-neutral society - a feasibility study
Meinusch, Nicole; Kramer, Susanne; Körner, Oliver; Wiese, Jürgen; Seick, Ingolf; Beblek, Anita; Berges, Regine; Illenberger, Bernhard; Illenberger, Marco; Uebbing, Jennifer; Wolf, Maximilian; Saake, Gunter; Benndorf, Dirk; Reichl, Udo; Heyer, Robert
In: Sustainability - Basel : MDPI, Bd. 13 (2021), Heft 17, Artikel 9505, insges. 22 S.
Begutachteter Zeitschriftenartikel
Towards integrated production of an influenza A vaccine candidate with MDCK suspension cells
Bissinger, Thomas; Wu, Yixiao; Marichal-Gallardo, Pável Alejandro; Riedel, Dietmar; Liu, Xuping; Genzel, Yvonne; Tan, Wen-Song; Reichl, Udo
In: Biotechnology & bioengineering - New York, NY [u.a.]: Wiley, Bd. 118 (2021), 10, S. 3996-4013
Begutachteter Zeitschriftenartikel
Antiviral activity of influenza A virus defective interfering particles against SARS-CoV-2 replication in vitro through stimulation of innate immunity
Rand, Ulfert; Kupke, Sascha Young; Shkarlet, Hanna; Hein, Marc Dominique; Hirsch, Tatjana; Marichal-Gallardo, Pável Alejandro; Cicin-Sain, Luka; Reichl, Udo; Bruder, Dunja
In: Cells - Basel: MDPI, 2012, Bd. 10 (2021), 7, insges. 14 S.
Begutachteter Zeitschriftenartikel
Cell culture-based production and in vivo characterization of purely clonal defective interfering influenza virus particles
Hein, Marc D.; Arora, Prerna; Marichal-Gallardo, Pável Alejandro; Winkler, Michael; Genzel, Yvonne; Pöhlmann, Stefan; Schughart, Klaus; Kupke, Sascha Y.; Reichl, Udo
In: BMC biology - Berlin: Springer, Bd. 19 (2021)
Begutachteter Zeitschriftenartikel
Associated viral gene transfer vectors by membrane-based steric exclusion chromatography
Marichal-Gallardo, Pavel; Börner, Kathleen; Pieler, Michael M.; Sonntag-Buck, Vera; Obr, Martin; Bejarano, David; Wolff, Michael W.; Kräusslich, Hans-Georg; Reichl, Udo; Grimm, Dirk
In: Human gene therapy - New York, NY: Liebert, 2021, insgesamt 16 Seiten
Begutachteter Zeitschriftenartikel
Site-specific N-glycosylation analysis of animal cell culture-derived Zika virus proteins
Pralow, Alexander; Nikolay, Alexander; Leon, Arnaud; Genzel, Yvonne; Rapp, Erdmann; Reichl, Udo
In: Scientific reports - [London] : Macmillan Publishers Limited, part of Springer Nature, Bd. 11 (2021), Artikel 5147
Begutachteter Zeitschriftenartikel
Comprehensive N‐glycosylation analysis of the influenza A virus proteins HA and NA from adherent and suspension MDCK cells
Pralow, Alexander; Hoffmann, Marcus; Nguyen-Khuong, Terry; Pioch, Markus; Hennig, René; Genzel, Yvonne; Rapp, Erdmann; Reichl, Udo
In: The FEBS journal / Vereinigung der Europäischen Biochemischen Gesellschaften - Oxford [u.a.] : Wiley-Blackwell, Bd. 288 (2021), Heft 16, S. 4869-4891
Begutachteter Zeitschriftenartikel
High cell density perfusion process for high yield of influenza A virus production using MDCK suspension cells
Wu, Yixiao; Bissinger, Thomas; Genzel, Yvonne; Liu, Xuping; Reichl, Udo; Tan, Wen-Song
In: Applied microbiology and biotechnology - Berlin: Springer, Bd. 105 (2021), 4, S. 1421-1434
Begutachteter Zeitschriftenartikel
Multienzyme cascades for the in vitro synthesis of guanosine diphosphate Lfucose
Mahour, Reza; Marichal-Gallardo, Pavel A.; Rexer, Thomas; Reichl, Udo
In: ChemCatChem - Weinheim: WILEY-VCH Verlag, Bd. 13 (2021), insges. 11 S.
Begutachteter Zeitschriftenartikel
Forschungsarbeiten am Institut für Verfahrenstechnik der OttovonGuerickeUniversität Magdeburg
Reichl, Udo; Seidel-Morgenstern, Andreas; Sundmacher, Kai; Tsotsas, Evangelos; Wachem, Berend
In: Chemie - Ingenieur - Technik - Weinheim : Wiley-VCH Verl., Bd. 93 (2021), Heft 3, S. 345-352
Begutachteter Zeitschriftenartikel
OP7, a novel influenza A virus defective interfering particle - production, purification, and animal experiments demonstrating antiviral potential
Hein, Marc D.; Kollmus, Heike; Marichal-Gallardo, Pavel; Püttker, Sebastian; Benndorf, Dirk; Genzel, Yvonne; Schughart, Klaus; Kupke, Sascha Y.; Reichl, Udo
In: Applied microbiology and biotechnology - Berlin : Springer , 1975, Bd. 105 (2021), Heft 1, S. 129-146
Begutachteter Zeitschriftenartikel
Critical Assessment of MetaProteome Investigation (CAMPI) - a multi-laboratory comparison of established workflows
Van Den Bossche, Tim; Kunath, Benoit J.; Schallert, Kay; Schäpe, Stephanie S.; Abraham, Paul C.; Armengaud, Jean; Arntzen, Magnus Ø.; Bassignani, Ariane; Benndorf, Dirk; Fuchs, Steohan; Giannone, Richard J.; Griffin, Timothy J.; Hagen, Live H.; Halder, Rashi; Henry, Céline; Hettich, Robert L.; Heyer, Robert; Jagtap, Pratik; Jehmlich, Nico; Jensen, Marlene; Juste, Ctherine; Kleiner, Manuel; Langella, Olivier; Lehmann, Theresa; Leith, Emma; May, Patrick; Mesuere, Bart; Miotello, Guylaine; Peters, Samantha L.; Pible, Olivier; Queiros, Pedro T.; Reichl, Udo; Renard, Bernhard Y.; Schiebenhoefer, Henning; Sczyrba, Alexander; Tanca, Alessandro; Trappe, Kathrin; Trezzi, jean-Pierre; Uzzau, Sergio; Verschaffelt, Pieter; Bergen, Martin von; Wilmes, Paul; Wolf, Maximilian; Martens, Lennart; Muth, Thilo
In: Nature Communications - [London] : Nature Publishing Group UK , 2010, Bd. 12 (2021), S. 1-15, Artikel 7305
Begutachteter Zeitschriftenartikel
Semi-continuous propagation of influenza A virus and its defective interfering particles - analyzing the dynamic competition to select candidates for antiviral therapy
Pelz, Lars; Rüdiger, Daniel; Dogra, Tanya; Alnaji, Fadi G.; Genzel, Yvonne; Brooke, Christopher B.; Kupke, Sascha Y.; Reichl, Udo
In: Journal of virology - Baltimore, Md.: Soc., Bd. 95 (2021), 24, insges. 18 S.
Begutachteter Zeitschriftenartikel
Cell-free multi-enzyme synthesis and purification of uridine diphosphate galactose
Mahour, Reza; Lee, Ju Weon; Grimpe, Pia; Boecker, Simon; Grote, Valerian; Klamt, Steffen; Seidel-Morgenstern, Andreas; Rexer, Thomas F. T.; Reichl, Udo
In: ChemBioChem - Weinheim: Wiley-VCH, Bd. 22 (2021), S. 1-11
Begutachteter Zeitschriftenartikel
MPA_Pathway_Tool - user-friendly, automatic assignment of microbial community data on metabolic pathways
Walke, Daniel; Schallert, Kay; Ramesh, Prasanna; Benndorf, Dirk; Lange, Emanuel; Reichl, Udo; Heyer, Robert
In: International journal of molecular sciences - Basel : Molecular Diversity Preservation International, Bd. 22 (2021), Heft 20, Artikel 10992, insges. 12 S.
Begutachteter Zeitschriftenartikel
Continuous purification of influenza A virus particles using pseudo-affinity membrane chromatography
Fortuna, Raquel A.; Taft, Florian; Villain, Louis; Wolff, Michael W.; Reichl, Udo
In: Journal of biotechnology - Amsterdam [u.a.]: Elsevier Science, Bd. 342 (2021), S. 139-148
Dissertation
Process intensification and integration for the production of vaccines and viral vectors
Gränicher, Gwendal; Reichl, Udo
In: Magdeburg: Universitätsbibliothek, 2021, 1 Online-Ressource (XXX, 222 Seiten, 8,49 MB), Illustrationen, Diagramme
Dissertation
Process intensification for the production of MVA and influenza A virus in high density suspension cultures of AGE1.CR.pIX cells
Vázquez Ramírez, Daniel; Reichl, Udo
In: Magdeburg: Universitätsbibliothek, 2021, 1 Online-Ressource (XIV, 136 Seiten, 7,58 MB), Illustrationen
Dissertation
Mathematical models of influenza A virus infection - elucidating the impact of host cell factors and defective interfering particles on virus growth
Laske, Tanja; Sundmacher, Kai; Reichl, Udo
In: Magdeburg: Universitätsbibliothek, 2021, 1 Online-Ressource (XVIII, 233 Seiten, 17,07 MB), Illustrationen, Diagramme
Dissertation
Metaproteomanalyse methanogener Mikrobiome aus Anreicherungskulturen im Labormaßstab
Kohrs, Fabian; Reichl, Udo
In: Magdeburg: Universitätsbibliothek, 2021, 1 Online-Ressource (IX, 123, A-J Seiten, 3,84 MB), Illustrationen
Dissertation
Scalable multi-enzyme platforms for the in vitro glycoengineering of therapeutic proteins & synthesis of human milk oligosaccharides
Mahour, Reza; Reichl, Udo
In: Magdeburg: Universitätsbibliothek, 2022, 1 Online-Ressource (XV, 170 Blätter, 5,8 MB), Illustrationen
Dissertation
Application of functional metagenomics to the field of glycobiology
Chuzel, Léa; Reichl, Udo
In: Düren: Shaker Verlag, 2022, Dissertation Otto-von-Guericke-Universität Magdeburg, Fakultät für Verfahrens- und Systemtechnik 2021, XI, 229 Seiten - (Forschungsberichte aus dem Max-Planck-Institut für Dynamik komplexer technischer Systeme; Band 55), ISBN: 3-8440-8437-1 [Literaturverzeichnis: Seite 186-210]
Herausgeberschaft
Advances in glycobiotechnology
Rapp, Erdmann; Reichl, Udo
In: Cham: Springer, 2021, viii, 461 Seiten - (Advances in biochemical engineering/biotechnology; 175), ISBN: 978-3-030-69589-7
2020
Artikel in Zeitschrift
Synthesis of lipid-linked oligosaccharides by a compartmentalized multi-enzyme cascade for the in vitro N-glycosylation of peptides
Rexer, Thomas F. T.; Wenzel, Lisa; Hoffmann, Marcus; Tischlik, Sebastian; Bergmann, Christin; Grote, Valerian; Boecker, Simon Matthias; Bettenbrock, Katja; Schildbach, Anna; Kottler, Robert; Mahour, Reza; Rapp, Erdmann; Pietzsch, Markus; Reichl, Udo
In: Journal of biotechnology - Amsterdam [u.a.]: Elsevier Science, 1984, Bd. 322 (2020), S. 54-65
Aufsatz
Impact of feeding and stirring regimes on the internal stratification of microbial communities in the fermenter of anaerobic digestion plants
Heyer, Robert; Klang, Johanna; Hellwig, Patrick; Schallert, Kay; Kress, Philipp; Hülsemann, Benedikt; Theuerl, Susanne; Reichl, Udo; Benndorf, Dirk
In: Bioresource technology - Amsterdam [u.a.] : Elsevier Science - 314(2020), Artikel-Nummer 123679, 1 Online-Ressource
Buchbeitrag
Perfusion control for high cell density cultivation and viral vaccine production
Nikolay, Alexander; Bissinger, Thomas; Gränicher, Gwendal; Wu, Yixiao; Genzel, Yvonne; Reichl, Udo
In: Animal Cell Biotechnology: Methods and Protocols - New York, NY: Springer US; Pörtner, Ralf . - 2020, S. 141-168
Begutachteter Zeitschriftenartikel
A dynamic model linking cell growth to intracellular metabolism and extracellular byproduct accumulation
Ramos, João R.; Rath, Alexander G.; Genzel, Yvonne; Sandig, Volker; Reichl, Udo
In: Biotechnology & bioengineering - New York, NY [u.a.]: Wiley . - 2020, insges. 21 S.
Begutachteter Zeitschriftenartikel
Performance of an acoustic settler versus a hollow fiberbased ATF technology for influenza virus production in perfusion
Gränicher, Gwendal; Coronel, Juliana; Trampler, Felix; Jordan, Ingo; Genzel, Yvonne; Reichl, Udo
In: Applied microbiology and biotechnology - Berlin: Springer, Bd. 104.2020, S. 4877-4888
Begutachteter Zeitschriftenartikel
Production of Modified Vaccinia Ankara virus by intensified cell cultures - a comparison of platform technologies for viral vector production
Gränicher, Gwendal; Tapia, Felipe; Behrendt, Ilona; Jordan, Ingo; Genzel, Yvonne; Reichl, Udo
In: Biotechnology journal - Weinheim: Wiley-VCH, Bd. 16 (2021), 1, insges. 10 S., 2020
Begutachteter Zeitschriftenartikel
Virus harvesting in perfusion culture - choosing the right type of hollow fiber membrane
Nikolay, Alexander; Grooth, Joris; Genzel, Yvonne; Wood, Jeffery A.; Reichl, Udo
In: Biotechnology & bioengineering - New York, NY [u.a.]: Wiley, 2020, insgesamt 13 Seiten[Online first]
Begutachteter Zeitschriftenartikel
Single-cell analysis uncovers a vast diversity in intracellular viral defective interfering RNA content affecting the large cell-to-cell heterogeneity in influenza A virus replication
Kupke, Sascha Young; Ly, Lam-Ha; Börno, Stefan Thomas; Ruff, Alexander; Timmermann, Bernd; Vingron, Martin; Haas, Stefan; Reichl, Udo
In: Viruses - Basel: MDPI, 12 (2020,1), Artikelnummer 71, 19 Seiten
Begutachteter Zeitschriftenartikel
Application of an nnclined settler for cell culture-based influenza A virus production in perfusion mode
Coronel, Juliana; Gränicher, Gwendal; Sandig, Volker; Noll, Thomas; Genzel, Yvonne; Reichl, Udo
In: Frontiers in Bioengineering and Biotechnology - Lausanne: Frontiers Media, Volume 8 (2020), article 672, insgesmat 13 Seiten
Dissertation
Intensified yellow fever and Zika virus production in animal cell culture
Nikolay, Alexander; Reichl, Udo
In: Magdeburg, 2020, XV, 175 Seiten, Illustrationen, Diagramme, 30 cm[Literaturverzeichnis: Seite 139-157]
Dissertation
Evaluation of MDCK suspension cell lines for influenza A virus production - media, metabolism, and process conditions
Bissinger, Thomas; Reichl, Udo
In: Magdeburg, 2020, XXVI, 137 Seiten, Illustrationen, Diagramme, 30 cm
Dissertation
In-depth mass spectrometry-based glycoproteomics - advances in sample preparation, measurement and data-analysis of glycoproteins
Hoffmann, Marcus; Reichl, Udo; Rapp, Erdmann
In: Magdeburg, 2020, XI, 141 Seiten, Illustrationen, Diagramme, 30 cm[Literaturverzeichnis: Seite 118-133]
Dissertation
Single-cell analysis of influenza A virus replication - sources of cell-to-cell heterogeneity and discoverey of a novel type of defective interfering particle
Kupke, Sascha Young; Reichl, Udo
In: Magdeburg, 2020, XV, 155 Seiten, Illustrationen, Diagramme, 30 cm[Literaturverzeichnis: Seite 122-136]
2019
Abstract
Dialyseinduzierte Veränderungen im menschlichen Serum-Protein N-Glykosylation
Lindquist, Jonathan; Hennig, René; Rapp, Erdmann; Reichl, Udo; Mertens, Peter Rene
In: Kongress für Nephrologie, 11. Jahrestagung der Deutschen Gesellschaft für Nephrologie: Die Nephrologie als ganzheitliche Disziplin in der Patientenversorgung : 10. 13. Oktober 2019 in Düsseldorf : Programm/ Kongress für Nephrologie, 2019, P256, S. 165
Aufsatz
RedCom - a strategy for reduced metabolic modeling of complex microbial communities and its application for analyzing experimental datasets from anaerobic digestion
Koch, Sabine; Kohrs, Fabian; Lahmann, Patrick; Bissinger, Thomas; Wendschuh, Stefan; Benndorf, Dirk; Reichl, Udo
In: PLoS Computational Biology / Public Library of Science - San Francisco, Calif. : Public Library of Science - Vol. 15 (2019), 2, Artikel e1006759, insgesamt 32 Seiten
Begutachteter Zeitschriftenartikel
High-throughput serum N-glycomics - method comparison and application to study rheumatoid arthritis and pregnancy-associated changes
Reiding, Karli R.; Bondt, Albert; Hennig, René; Gardner, Richard A.; O'Flaherty, Roisin; Trbojevič-Akmačič, Irena; Shubhakar, Archana; Hazes, Johanna M. W.; Reichl, Udo; Fernandes, Daryl L.; Pučič-Bakovič, Maja; Rapp, Erdmann; Spencer, Daniel I. R.; Dolhain, Radboud J. E. M.; Rudd, Pauline M.; Lauc, Gordon; Wuhrer, Manfred
In: Molecular & cellular proteomics: MCP - Bethesda, Md: The American Society for Biochemistry and Molecular Biology, Bd. 18.2019, 1, S. 3-15
Begutachteter Zeitschriftenartikel
Enzymatic cascade synthesis provides novel linear human milk oligosaccharides as reference standards for xCGELIF based highthroughput analysis
Fischöder, Thomas; Cajic, Samanta; Reichl, Udo; Rapp, Erdmann; Elling, Lothar
In: Biotechnology journal - Weinheim: Wiley-VCH, Vol. 14 (2019), 3, Artikelnr. 1800305, insges. 9 Seiten
Begutachteter Zeitschriftenartikel
Continuous influenza virus production in a tubular bioreactor system provides stable titers and avoids the von Magnus effect
Tapia Delgado, Felipe Ignacio; Wohlfahrth, Daniel; Sandig, Volker; Jordan, Ingo; Genzel, Yvonne; Reichl, Udo
In: PLOS ONE - San Francisco, California, US: PLOS, 2006, 14 (2019), 11, article e0224317, insgesamt 21 Seiten
Begutachteter Zeitschriftenartikel
Hydrophobic-interaction chromatography for purification of influenza A and B virus
Weigel, Thomas; Soliman, Remon; Wolff, Michael W.; Reichl, Udo
In: Journal of chromatography / B - New York, NY [u.a.]: Science Direct, Bd. 1117.2019, S. 103-117
Begutachteter Zeitschriftenartikel
High titer MVA and influenza A virus production using a hybrid fed-batch/perfusion strategy with an ATF system
Vázquez Ramírez, Daniel; Jordan, Ingo; Sandig, Volker; Genzel, Yvonne; Reichl, Udo
In: Applied microbiology and biotechnology - Berlin: Springer, Bd. 103 (2019), 7, S. 3025-3035
Begutachteter Zeitschriftenartikel
A system for production of defective interfering particles in the absence of infectious influenza A virus
Bdeir, Najat; Arora, Prerna; Gärtner, Sabine; Hoffmann, Markus; Reichl, Udo; Pöhlmann, Stefan; Winkler, Michael
In: PLOS ONE - San Francisco, California, US: PLOS, Vol. 14.2019, 3, Artikel e0212757, insgesamt 18 Seiten
Begutachteter Zeitschriftenartikel
A novel type of influenza a virus-derived defective interfering particle with nucleotide substitutions in its genome
Kupke, Sascha Young; Riedel, Dietmar; Frensing, Timo; Zmora, Pawel; Reichl, Udo
In: Journal of virology: publ. by the American Society for Microbiology - Baltimore, Md.: Soc., 1967, Bd. 93.2019, 4, Art.-Nr. e01786, insges. 24 Seiten
Begutachteter Zeitschriftenartikel
Influenza A virus production in a single-use orbital shaken bioreactor with ATF or TFF perfusion systems
Coronel, Juliana; Behrendt, Ilona; Bürgin, Tim; Anderlei, Tibor; Sandig, Volker; Reichl, Udo; Genzel, Yvonne
In: Vaccine - Amsterdam: Elsevier, Bd. 37.2019, 47, S. 7011-7018
Begutachteter Zeitschriftenartikel
Semi-perfusion cultures of suspension MDCK cells enable high cell concentrations and efficient influenza A virus productionPK2.1
Bissinger, Thomas; Fritsch, Johannes; Mihut, Adrian; Wu, Yxiao; Liu, Xuping; Genzel, Yvonne; Tan, Wen-Song; Reichl, Udo
In: Vaccine - Amsterdam: Elsevier, Bd. 37 (2019), 47, S. 7003-7010
Begutachteter Zeitschriftenartikel
Efficient influenza A virus production in high cell density using the novel porcine suspension cell line PBG.PK2.1
Gränicher, Gwendal; Coronel, Juliana; Pralow, Alexander; Marichal-Gallardo, Pável Alejandro; Wolff, Michael; Rapp, Erdmann; Karlas, Alexander; Sandig, Volker; Genzel, Yvonne; Reichl, Udo
In: Vaccine - Amsterdam: Elsevier, 1983, Bd. 37.2019, 47, S. 7019-7028
Begutachteter Zeitschriftenartikel
Production of Defective Interfering Particles of influenza A virus in parallel continuous cultures at two residence times - insights from qPCR measurements and viral dynamics modeling
Tapia Delgado, Felipe Ignacio; Laske, Tanja; Wasik, Milena A.; Rammhold, Markus; Genzel, Yvonne; Reichl, Udo
In: Frontiers in Bioengineering and Biotechnology - Lausanne: Frontiers Media, 2013, Volume 7 (2019), Artikel 275, insgesamt 15 Seiten
Begutachteter Zeitschriftenartikel
Enzymatic cascades for tailored 13 C 6 and 15 N enriched human milk oligosaccharides
Fischöder, Thomas; Cajic, Samanta; Grote, Valerian; Greifenstein, Raphael; Reichl, Udo; Franzreb, Matthias; Rapp, Erdmann; Elling, Lothar
In: Molecules: a journal of synthetic chemistry and natural product chemistry - Basel: MDPI, 1996, Volume 24 (2019), 19, Artikel 3482, insgesamt 21 Seiten
Begutachteter Zeitschriftenartikel
A robust and universal metaproteomics workflow for research studies and routine diagnostics within 24 h using phenol extraction, FASP digest, and the MetaProteomeAnalyzer
Heyer, Robert; Schallert, Kay; Büdel, Anja; Zoun, Roman; Dorl, Sebastian; Behne, Alexander; Kohrs, Fabian; Püttker, Sebastian; Siewert, Corina; Muth, Thilo; Saake, Gunter; Reichl, Udo; Benndorf, Dirk
In: Frontiers in microbiology - Lausanne: Frontiers Media, 10 (2019), article 1883, insgesamt 20 Seiten
Begutachteter Zeitschriftenartikel
Use of sulfated cellulose membrane adsorbers for chromatographic purification of cell cultured-derived influenza A and B viruses
Fortuna, A. Raquel; van Teeffelen, Sebastian; Ley, Adrian; Fischer, Laura M.; Taft, Florian; Genzel, Yvonne; Villain, Louis; Wolff, Michael W.; Reichl, Udo
In: Separation and purification technology - Amsterdam [u.a.]: Elsevier Science, 1997, Bd. 226.2019, S. 350-358
Begutachteter Zeitschriftenartikel
Metaproteomics of fecal samples of Crohn's disease and Ulcerative Colitis
Lehmann, Tony; Schallert, Kay; Vilchez-Vargas, Ramiro; Benndorf, Dirk; Püttker, Sebastian; Sydor, Svenja; Schulz, Christian; Bechmann, Lars Peter; Canbay, Ali E.; Heidrich, Benjamin; Reichl, Udo; Link, Alexander; Heyer, Robert
In: Journal of proteomics - New York, NY [u.a.] : Elsevier, Bd. 201 (2019), S. 93-103
Begutachteter Zeitschriftenartikel
Metaproteome analysis reveals that syntrophy, competition, and phage-host interaction shape microbial communities in biogas plants
Heyer, Robert; Schallert, Kay; Siewert, C.; Kohrs, F.; Greve, J.; Maus, I.; Klang, J.; Klocke, M.; Heiermann, M.; Hoffmann, Michael; Püttker, Sebastian; Calusinska, M.; Zoun, Roman; Saake, Gunter; Benndorf, Dirk; Reichl, Udo
In: Microbiome - London : Biomed Central, Bd. 7 (2019), Artikel 69, insges. 17 S.
Dissertation
Herstellungsprozess für onkolytische Masernviren
Grein, Tanja A.; Reichl, Udo
In: Düren: Shaker Verlag, 2019, XII, 195 Seiten, 24 Illustrationen, Diagramme, 21 cm, 314 g - (Schriftenreihe des Institutes für Bioverfahrenstechnik und Pharmazeutische Technologie; Band 15)
Dissertation
Continuous upstream processing for cell culture-derived virus production
Tapia Delgado, Felipe Ignacio; Reichl, Udo
In: Magdeburg, 2019, xv, 112 Blätter, Illustrationen, Diagramme, 30 cm
Dissertation
Chromatographic purification of biological macromolecules by their capture on hydrophilic surfaces with the aid of non-ionic polymers
Marichal-Gallardo, Pável Alejandro; Reichl, Udo
In: Magdeburg, 2019, xiii, 118 Blätter, Illustrationen, Diagramme, 30 cm
Dissertation
Charakterisierung der Influenzavirus-Vermehrung in genetisch veränderten humanen Zelllinien zur Optimierung der Impfstoffproduktion
Bachmann, Mandy; Reichl, Udo
In: Magdeburg, 2019, XI, 173 Seiten, Illustrationen, Diagramme, 30 cm[Literaturverzeichnis: Seite 133-155]
2018
Begutachteter Zeitschriftenartikel
A multiscale model of influenza A virus replication covering highly different infection conditions in cell cultures
Rüdiger, D.; Kupke, S. Y.; Reichl, Udo
In: IFAC-PapersOnLine/ Internationale Förderung für Automatische Lenkung - Frankfurt: Elsevier, Bd. 51.2018, 19, S. 32-33[Konferenz: 7th Conference on Foundation of Systems Biology in Engineering, FOSBE 2018, Chicago, Illinois, USA, 05-08 August 2018]
Begutachteter Zeitschriftenartikel
Improvement of electrospray stability in negative ion mode for nano-PGC-LC-MS glycoanalysis via post-column make-up flow
Nguyen-Khuong, Terry; Pralow, Alexander; Reichl, Udo; Rapp, Erdmann
In: Glycoconjugate journal: official journal of the International Glycoconjugate Organization - Dordrecht [u.a.]: Springer Science + Business Media B.V, Bd. 35.2018, 6, S. 499-509
Begutachteter Zeitschriftenartikel
The fine art of destruction - a guide to indepth glycoproteomic analyses-exploiting the diagnostic potential of fragment ions
Hoffmann, Marcus; Pioch, Markus; Pralow, Alexander; Henning, René; Kottler, Robert; Reichl, Udo; Rapp, Erdmann
In: Proteomics - Weinheim: Wiley VCH, 2001, Vol. 18.2018, 24, Art.-Nr. 1800282
Begutachteter Zeitschriftenartikel
glyXtoolMS - an open-source pipeline for semiautomated analysis of glycopeptide mass spectrometry data
Pioch, Markus; Hoffmann, Marcus; Prahlow, Alexander; Reichl, Udo; Rapp, Erdmann
In: Analytical chemistry: the authoritative voice of the analytical community - Columbus, Ohio: American Chemical Society, 1947, Bd. 90.2018, 20, S. 11908-11916
Begutachteter Zeitschriftenartikel
Mathematical modeling as a tool to improve influenza vaccine production processes
Duvigneau, Stefanie; Dürr, Robert; Laske, Tanja; Bachmann, Mandy; Dostert, Melanie; Reichl, Udo; Kienle, Achim
In: IFAC-PapersOnLine / Internationale Förderung für Automatische Lenkung - Frankfurt : Elsevier , 2015, Bd. 51 (2018), Heft 19, S. 1-4
Begutachteter Zeitschriftenartikel
Process intensification of EB66® cell cultivations leads to high-yield yellow fever and Zika virus production
Nikolay, Alexander; Léon, Arnaud; Schwamborn, Klaus; Genzel, Yvonne; Reichl, Udo
In: Applied microbiology and biotechnology - Berlin: Springer, 1975, Bd. 102.2018, 20, S. 8725-8737
Begutachteter Zeitschriftenartikel
Propagation of Brazilian Zika virus strains in static and suspension cultures using Vero and BHK cells
Nikolay, Alexander; Castilho, Leda R.; Reichl, Udo; Genzel, Yvonne
In: Vaccine - Amsterdam: Elsevier, 1983, Bd. 36.2018, 22, S. 3140-3145
Begutachteter Zeitschriftenartikel
Purification of influenza viruslike particles using sulfated cellulose membrane adsorbers
Carvalho, Sofia B.; Fortuna, A. Raquel; Wolff, Michael W.; Peixoto, Cristina; Alves, Paula M.; Reichl, Udo
In: Journal of chemical technology & biotechnology - Chichester: Wiley, Bd. 93.2018, 7, S. 1988-1996[Special issue: Bioseparations]
Begutachteter Zeitschriftenartikel
Establishment of a five-enzyme cell-free cascade for the synthesis of uridine diphosphate N-acetylglucosamine
Mahour, Reza; Klapproth, Jan; Rexer, Thomas F. T.; Schildbach, Anna; Klamt, Steffen; Pietzsch, Markus; Rapp, Erdmann; Reichl, Udo
In: Journal of biotechnology - Amsterdam [u.a.]: Elsevier Science, Bd. 283.2018, S. 120-129
Begutachteter Zeitschriftenartikel
SDSPAGE fractionation to increase metaproteomic insight into the taxonomic and functional composition of microbial communities for biogas plant samples
Wenzel, Lisa; Heyer, Robert; Schallert, Kay; Löser, Lucy; Wünschiers, Röbbe; Reichl, Udo; Benndorf, Dirk
In: Engineering in life sciences - Weinheim : Wiley-VCH, Bd. 18 (2018), Heft 7, S. 498-509
Begutachteter Zeitschriftenartikel
Valorisation of deinking sludge as a substrate for lignocellulolytic enzymes production by Pleurotus ostreatus
Vodovnik, Maša; Vrabec, Katja; Hellwig, Patrick; Benndorf, Dirk; Sežun, Mija; Gregori, Andrej; Gottumukkala, Lalitha D.; Anderson, Robin C.; Reichl, Udo
In: Journal of cleaner production - Amsterdam [u.a.]: Elsevier Science, Vol. 197.2018, Part 1, S. 253-263
Begutachteter Zeitschriftenartikel
Purification of cell culture-derived influenza A virus via continuous anion exchange chromatography on monoliths
Fischer, Laura M.; Wolff, Michael; Reichl, Udo
In: Vaccine - Amsterdam: Elsevier, Bd. 36.2018, 22, S. 3153-3160
Begutachteter Zeitschriftenartikel
High-cell-density cultivations to increase MVA virus production
Vázquez Ramírez, Daniel; Genzel, Yvonne; Jordan, Ingo; Sandig, Volker; Reichl, Udo
In: Vaccine - Amsterdam: Elsevier, Bd. 36 (2018), 22, S. 3124-3133
Begutachteter Zeitschriftenartikel
MPA portable - a stand-alone software package for analyzing metaproteome samples on the go
Muth, Thilo; Kohrs, Fabian; Heyer, Robert; Benndorf, Dirk; Rapp, Erdmann; Reichl, Udo; Martens, Lennart; Renard, Bernhard Y.
In: Analytical chemistry - Columbus, Ohio : American Chemical Society , 1947, Bd. 90 (2018), Heft 1, S. 685-689
Begutachteter Zeitschriftenartikel
Optimization of cell culture-derived influenza A virus particles purification using sulfated cellulose membrane adsorbers
Fortuna, Ana Raquel; Taft, Florian; Villain, Louis; Wolff, Michael W.; Reichl, Udo
In: Engineering in life sciences - Weinheim: Wiley-VCH, Bd. 18.2018, 1, S. 29-39
Begutachteter Zeitschriftenartikel
Cell culture-based production of defective interfering particles for influenza antiviral therapy
Wasik, Milena A.; Eichwald, Luca; Genzel, Yvonne; Reichl, Udo
In: Applied microbiology and biotechnology - Berlin: Springer, 1975, Bd. 102.2018, 3, S. 1167-1177, 2017
2017
Buchbeitrag
Animal cell expression systems
Butler, M.; Reichl, Udo
In: Advances in biochemical engineering, biotechnology - Berlin: Springer, S. 1-36, 2017[Online first]
Begutachteter Zeitschriftenartikel
Proteotyping of laboratory-scale biogas plants reveals multiple steady-states in community composition
Kohrs, Fabian; Heyer, Robert; Bissinger, Thomas; Kottler, Robert; Schallert, Kay; Püttker, Sebastian; Behne, Alexander; Rapp, Erdmann; Benndorf, Dirk; Reichl, Udo
In: Anaerobe - London : Academic Press , 1995, Bd. 46 (2017), S. 56-68
Begutachteter Zeitschriftenartikel
Specific ion effects on the particle size distributions of cell culturederived influenza A virus particles within the Hofmeister series
Pieler, Michael Martin; Heyse, Anja; Wolff, Michael Werner; Reichl, Udo
In: Engineering in life sciences - Weinheim : Wiley-VCH, Bd. 17.2017, 5, S. 470-478
Begutachteter Zeitschriftenartikel
Improvement of the glycoproteomic toolbox with the discovery of a unique C-terminal cleavage specificity of flavastacin for N-glycosylated asparagine
Pralow, Alexander; Hoffmann, Marcus; Nguyen-Khuong, Terry; Rapp, Erdmann; Reichl, Udo
In: Scientific reports - [London] : Macmillan Publishers Limited, part of Springer Nature - Bd. 7.2017, Art.-Nr. 11419, insgesamt 9 Seiten
Begutachteter Zeitschriftenartikel
Steric exclusion chromatography for purification of cell culture-derived influenza A virus using regenerated cellulose membranes and polyethylene glycol
Marichal-Gallardo, Pável Alejandro; Pieler, Michael M.; Wolff, Michael W.; Reichl, Udo
In: Journal of chromatography - New York, NY [u.a.] : Science Direct, Bd. 1483.2017, S. 110-119
Begutachteter Zeitschriftenartikel
One pot synthesis of GDP-mannose by a multi-enzyme cascade for enzymatic assembly of lipid-linked oligosaccharides
Rexer, Thomas F. T.; Schildbach, Anna; Klapproth, Jan; Schierhorn, Angelika; Mahour, Reza; Pietzsch, Markus; Rapp, Erdmann; Reichl, Udo
In: Biotechnology & bioengineering - New York, NY [u.a.]: Wiley, Bd. 115 (2018), 1, S. 192-205
Begutachteter Zeitschriftenartikel
Influence of the production system on the surface properties of influenza A virus particles
Hämmerlein, Frank; Pieler, Michael M.; Hennig, René; Serve, Anja; Rapp, Erdmann; Wolff, Michael W.; Reichl, Udo; Hubbuch, Jürgen
In: Engineering in life sciences - Weinheim : Wiley-VCH, Bd. 17.2017, 10, S. 1071-1077
Begutachteter Zeitschriftenartikel
Efficient and stable production of Modified Vaccinia Ankara virus in two-stage semi-continuous and in continuous stirred tank cultivation systems
Tapia Delgado, Felipe Ignacio; Jordan, Ingo; Genzel, Yvonne; Reichl, Udo
In: PLOS ONE - San Francisco, California, US : PLOS - Bd. 12.2017, 8, Art.-Nr. e0182553, insges. 17 Seiten
Dissertation
Characterisation of cell growth, metabolism and recombinant protein production during transient and steady state conditions for the human cell line AGE1.HN.AAT
Rath, Alexander; Sundmacher, Kai; Reichl, Udo
In: Magdeburg, 2017, XV, 178, xvi Seiten, Illustrationen, Diagramme, 30 cm
Dissertation
Investigation of influenza virus particle aggregation and purification with magnetic sulfated cellulose particles
Pieler, Michael Martin; Reichl, Udo
In: Magdeburg, 2017, xxv, 97 Seiten, Illustrationen
Dissertation
Charakterisierung von mikrobiellen Gemeinschaften aus Biogasanlagen mittels Metaproteomanalyse und Korrelationen der Ergebnisse zu den Prozessparametern
Heyer, Robert Steven; Reichl, Udo
In: Magdeburg, Dissertation Otto-von-Guericke-Universität Magdeburg, Fakultät für Verfahrens- und Systemtechnik 2017, XVII, 164, xxxvii Blätter, Illustrationen
2016
Begutachteter Zeitschriftenartikel
Impaired antiviral response of adenovirus-transformed cell lines supports virus replication
Bachmann, Mandy; Breitwieser, Theresa; Lipps, Christoph; Wirth, Dagmar; Jordan, Ingo; Reichl, Udo; Frensing, Timo
In: Journal of general virology: JGV - Reading: Soc., 1967, Bd. 97.2016, 2, S. 293-298
Begutachteter Zeitschriftenartikel
Site-specific O-glycosylation analysis of human blood plasma proteins
Hoffmann, Marcus; Marx, Kristina; Reichl, Udo; Wuhrer, Manfred; Rapp, Erdmann
In: Molecular & cellular proteomics: MCP - Bethesda, Md: The American Society for Biochemistry and Molecular Biology, 2002, Bd. 15.2016, 2, S. 624-641
Begutachteter Zeitschriftenartikel
A membrane-based purification process for cell culture-derived influenza A virus
Weigel, Thomas; Solomaier, Thomas; Wehmeyer, Sebastian; Peuker, Alessa; Wolff, Michael W.; Reichl, Udo
In: Journal of biotechnology - Amsterdam [u.a.]: Elsevier Science, 1984, Bd. 220.2016, S. 12-20
Begutachteter Zeitschriftenartikel
Binding kinetics and multi-bond : finding correlations by synthesizing interactions between ligand-coated bionanoparticles and receptor surfaces
Wang, Wenjing; Voigt, Andreas; Wolff, Michael W.; Reichl, Udo; Sundmacher, Kai
In: Analytical biochemistry : methods in the biological sciences. - San Diego, Calif : Elsevier, Bd. 505.2016, S. 8-17
Begutachteter Zeitschriftenartikel
Metaproteomics applied to activated sludge for industrial wastewater treatment revealed a dominant methylotrophic metabolism of Hyphomicrobium zavarzinii
Salerno, Carlo; Benndorf, Dirk; Pech, Sabine; Palese, Luigi Leonardo; Reichl, Udo; Pollice, Alfieri
In: Microbial ecology - New York, NY: Springer . - 2016
Begutachteter Zeitschriftenartikel
Bioreactors for high cell density and continuous multi-stage cultivations: options for process intensification in cell culture-based viral vaccine production
Tapia Delgado, Felipe Ignacio; Vázquez Ramírez, Daniel; Genzel, Yvonne; Reichl, Udo
In: Applied microbiology and biotechnology - Berlin: Springer, Bd. 100 (2016), 5, S. 2121-2132
Begutachteter Zeitschriftenartikel
Predicting compositions of microbial communities from stoichiometric models with applications for the biogas process
Koch, Sabine; Benndorf, Dirk; Fronk, Karen; Reichl, Udo; Klamt, Steffen
In: Biotechnology for biofuels - London: BioMed Central, Bd. 9 (2016), 17, insges. 16 S.
Begutachteter Zeitschriftenartikel
Early changes in the metabolic profile of activated CD8+ T cells
Cammann, Clemens; Rath, Alexander; Reichl, Udo; Lingel, Holger; Brunner-Weinzierl, Monika; Simeoni, Luca; Schraven, Burkhart; Lindquist, Jonathan A.
In: BMC cell biology - London : BioMed Central - Bd. 17.2016, Art.-Nr. 28, insges. 11 S.
Begutachteter Zeitschriftenartikel
Reprint of "Modeling the intracellular replication of influenza A virus in the presence of defective interfering RNAs
Laske, Tanja; Heldt, Frank Stefan; Hoffmann, Helene; Frensing, Timo; Reichl, Udo
In: Virus research : an international journal of molecular and cellular virology. - Amsterdam [u.a.] : Elsevier Science, Bd. 218.2016, S. 86-95
Begutachteter Zeitschriftenartikel
Diagnostic concept for dynamically operated biogas production plants
Bensmann, Astrid; Hanke-Rauschenbach, Richard; Heyer, Robert; Kohrs, Fabian; Benndorf, Dirk; Kausmann, Robert; Plöchl, Matthias; Heiermann, Monika; Reichl, Udo; Sundmacher, Kai
In: Renewable energy - Amsterdam [u.a.]: Elsevier Science, Vol. 96.2016, Part A, S. 479-489
Begutachteter Zeitschriftenartikel
Proteotyping of biogas plant microbiomes separates biogas plants according to process temperature and reactor type
Heyer, Robert; Benndorf, Dirk; Kohrs, F.; Vrieze, J.; Boon, N.; Hoffmann, M.; Rapp, Erdmann; Schlüter, A.; Sczyrba, A.; Reichl, Udo
In: Biotechnology for biofuels - London: BioMed Central, Bd. 9 (2016), 1
Begutachteter Zeitschriftenartikel
Glycomic characterization of induced pluripotent stem cells derived from a patient suffering from phosphomannomutase 2 congenital Disorder of glycosylation (PMM2-CDG)
Thiesler, Christina T.; Cajic, Samanta; Hoffmann, Dirk; Thiel, Christian; Diepen, Laura van; Hennig, René; Sgodda, Malte; Weiβmann, Robert; Reichl, Udo; Steinemann, Doris; Diekmann, Ulf; Huber, Nicolas M. B.; Oberbeck, Astrid; Cantz, Tobias; Kuss, Andreas W.; Körner, Christian; Schambach, Axel; Rapp, Erdmann; Buettner, Falk F. R.
In: Molecular & cellular proteomics - Bethesda, Md. : The American Society for Biochemistry and Molecular Biology, Bd. 15 (2016), Heft 4, S. 1435-1452
Begutachteter Zeitschriftenartikel
A cell culture-derived whole virus influenza A vaccine based on magnetic sulfated cellulose particles confers protection in mice against lethal influenza A virus infection
Pieler, Michael M.; Frentzel, Sarah; Bruder, Dunja; Wolff, Michael W.; Reichl, Udo
In: Vaccine - Amsterdam: Elsevier, 1983, Bd. 34.2016, 50, S. 6367-6374
Begutachteter Zeitschriftenartikel
Ezrin and HNRNP expression correlate with increased virus release rate and early onset of virus-induced apoptosis of MDCK suspension cells
Kluge, Sabine; Genzel, Yvonne; Laus, Kim; Serve, Anja; Pflugmacher, Antje; Peschel, Britta; Rapp, Erdmann; Reichl, Udo
In: Biotechnology journal : BTJ ; systems & synthetic biology, nanobiotech, medicine. - Weinheim : Wiley-VCH, Bd. 11.2016, 10, S. 1332-1342
Begutachteter Zeitschriftenartikel
Sialic acid-specific affinity chromatography for the separation of erythropoietin glycoforms using serotonin as a ligand
Meininger, M.; Stepath, M.; Hennig, R.; Cajic, S.; Rapp, E.; Rotering, H.; Wolff, M. W.; Reichl, Udo
In: Journal of chromatography / B - New York, NY [u.a.]: Science Direct, 1977, Bd. 1012/1013.2016, S. 193-203
Begutachteter Zeitschriftenartikel
Influenza virus intracellular replication dynamics, release kinetics, and particle morphology during propagation in MDCK cells
Frensing, Timo; Kupke, Sascha Young; Bachmann, Mandy; Fritzsche, Susanne; Gallo-Ramirez, Lili E.; Reichl, Udo
In: Applied microbiology and biotechnology - Berlin: Springer, 1975, Bd. 100.2016, 16, S. 7181-7192
Begutachteter Zeitschriftenartikel
Towards personalized diagnostics via longitudinal study of the human plasma N-glycome
Hennig, René; Cajic, Samanta; Borowiak, Matthias; Hoffmann, Marcus; Kottler, Robert; Reichl, Udo; Rapp, Erdmann
In: Biochimica et biophysica acta / General subjects: BBA - Amsterdam [u.a.]: Elsevier, 1964, Bd. 1860.2016, 8, S. 1728-1738
Dissertation
Novel computational methods for the analysis and interpretation of MS/MS data in metaproteomics
Muth, Thilo; Weiß, Helmut; Reichl, Udo
In: Magdeburg, 2016, XVI, 197 Seiten, Illustrationen
Dissertation
Modellbasierte Bestimmung von Interventionsstrategien zur Optimierung der Produktion von Biokraftstoffen in Cyanobakterien
Erdrich, Philipp; Reichl, Udo; Kienle, Achim
In: Magdeburg, 2016, xx, 158 Seiten, Illustrationen
Dissertation
Proteomanalytik der Adaption tierischer Zelllinien an Suspensionswachstum und optimierte Medien im Kontext der Impfstoffproduktion
Pech, Sabine; Reichl, Udo
In: Magdeburg: Otto-von-Guericke-Universität Magdeburg, 2016, XXIV, 192, lxxvii Seiten, Illustrationen, Diagramme, 30 cm
Dissertation
Purification of cell culture-derived influenza virus using simulated moving bed chromatography
Kröber, Tina; Reichl, Udo; Seidel-Morgenstern, Andreas
In: Magdeburg, 2016, XX, 171 Seiten, Illustrationen, Diagramme, 30 cm
Dissertation
Etablierung und Anwendung einer durchflusszytometrischen Methode für die Vitalitätsbestimmung von P. aeruginosa, B. cepacia und S. aureus in Mischkulturen
Rüger, Marc; Reichl, Udo
In: Magdeburg, 2016, XIV, 161, viii Blätter, Illustrationen
2015
Aufsatz
Metaproteomics of complex microbial communities in biogas plants
Heyer, Robert; Kohrs, Fabian; Reichl, Udo; Benndorf, Dirk
In: Microbial biotechnology - Oxford : Wiley-Blackwell, Bd. 8 (2015), Heft 5, S. 749-763
Aufsatz
The MetaProteomeAnalyzer - a powerful open-source software suite for metaproteomics data analysis and interpretation
Muth, Thilo; Behne, Alexander; Heyer, Robert; Kohrs, Fabian; Benndorf, Dirk; Hoffmann, Marcus; Lehtevä, Miro; Reichl, Udo; Martens, Lennart; Rapp, Erdmann
In: Journal of proteome research - Washington, DC : ACS Publications, Bd. 14 (2015), Heft 3, S. 1557-1565
Aufsatz
Fractionation of biogas plant sludge material improves metaproteomic characterization to investigate metabolic activity of microbial communities
Kohrs, Fabian; Wolter, Sophie; Benndorf, Dirk; Heyer, Robert; Hoffmann, Marcus; Rapp, Erdmann; Bremges, Andreas; Sczyrba, Alexander; Schlüter, Andreas; Reichl, Udo
In: Proteomics - Weinheim : Wiley VCH, Bd. 15 (2015), Heft 20, S. 3585-3589
Aufsatz
Metaproteomics of activated sludge from a wastewater treatment plant - a pilot study
Püttker, Sebastian; Kohrs, Fabian; Benndorf, Dirk; Heyer, Robert; Rapp, Erdmann; Reichl, Udo
In: Proteomics - Weinheim : Wiley VCH, Bd. 15 (2015), Heft 20, S. 3596-3601
Aufsatz
Comparison of influenza virus particle purification using magnetic sulfated cellulose particles with an established centrifugation method for analytics
Serve, Anja; Pieler, Michael Martin; Benndorf, Dirk; Rapp, Erdmann; Wolff, Michael Werner; Reichl, Udo
In: Analytical chemistry - Columbus, Ohio : American Chemical Society, Bd. 87 (2015), Heft 21, S. 10708-10711
Begutachteter Zeitschriftenartikel
Editorial: Can modern vaccine technology pursue the success of traditional vaccine manufacturing?
Grabherr, Reingard; Reichl, Udo
In: Biotechnology journal: BTJ : systems & synthetic biology, nanobiotech, medicine - Weinheim: Wiley-VCH, Bd. 10.2015, 5, S. 657-658
Begutachteter Zeitschriftenartikel
Bioreactor concepts for cell culture-based viral vaccine production
Gallo-Ramírez, Lilí Esmeralda; Nikolay, Alexander; Genzel, Yvonne; Reichl, Udo
In: Expert review of vaccines - Abingdon, Oxon: Taylor & Francis, 2002, Bd. 14.2015, 9, S. 1181-1195
Begutachteter Zeitschriftenartikel
Single-cell analysis and stochastic modelling unveil large cell-to-cell variability in influenza A virus infection
Heldt, Frank S.; Kupke, Sascha Young; Dorl, Sebastian; Reichl, Udo; Frensing, Timo
In: Nature Communications - [London]: Nature Publishing Group UK, 2010, Vol. 6.2015, Art. 8938, insgesamt 12 S.
Begutachteter Zeitschriftenartikel
Colonic metaproteomic signatures of active bacteria and the host in obesity
Kolmeder, Carolin A.; Ritari, Jarmo; Verdam, Froukje J.; Muth, Thilo; Keskitalo, Salla; Varjosalo, Markku; Fuentes, Susana; Greve, Jan Willem; Buurman, Wim A.; Reichl, Udo; Rapp, Erdmann; Martens, Lennart; Palva, Airi; Salonen, Anne; Rensen, Sander S.; Vos, Willem M.
In: Proteomics - Weinheim : Wiley VCH, Bd. 15 (2015), Heft 20, S. 3544-3552
Begutachteter Zeitschriftenartikel
Monitoring changes in proteome during stepwise adaptation of a MDCK cell line from adherence to growth in suspension
Pech, Sabine; Benndorf, Dirk; Genzel, Yvonne; Scharfenberg, Klaus; Rapp, Erdmann; Reichl, Udo
In: Vaccine - Amsterdam: Elsevier, Bd. 33 (2015), 35, S. 4269-4280
Begutachteter Zeitschriftenartikel
Navigating through metaproteomics data - a logbook of database searching
Muth, Thilo; Kolmeder, Carolin A.; Salojärvi, Jarkko; Keskitalo, Salla; Varjosalo, Markku; Verdam, Froukje J.; Rensen, Sander S.; Reichl, Udo; Vos, Willem M.; Rapp, Erdmann; Martens, Lennart
In: Proteomics - Weinheim: Wiley VCH, 2001, Bd. 15.2015, 20, S. 3439-3453
Begutachteter Zeitschriftenartikel
Exclusive decoration of simian immunodeficiency virus Env with high-mannose type N-glycans is not compatible with mucosal transmission in rhesus macaques
Karsten, Christina B.; Buettner, Falk F. R.; Cajic, Samanta; Nehlmeier, Inga; Neumann, Berit; Klippert, Antonina; Sauermann, Ulrike; Reichl, Udo; Gerardy-Schahn, Rita; Rapp, Erdmann; Stahl-Hennig, Christiane; Pöhlmann, Stefan
In: Journal of virology: publ. by the American Society for Microbiology - Baltimore, Md.: Soc., 1967, Bd. 89.2015, 22, S. 11727-11733
Begutachteter Zeitschriftenartikel
Modeling the intracellular replication of influenza A virus in the presence of defective interfering RNAs
Laske, Tanja; Heldt, Frank Stefan; Hoffmann, Helene; Frensing, Timo; Reichl, Udo
In: Virus research: an international journal of molecular and cellular virology - Amsterdam [u.a.]: Elsevier Science, 1984, Bd. 213.2015, S. 90-99
Begutachteter Zeitschriftenartikel
Community shifts in a well-operating agricultural biogas plant - how process variations are handled by the microbiome
Theuerl, Susanne; Kohrs, Fabian; Benndorf, Dirk; Maus, Irena; Wibberg, Daniel; Schlüter, Andres; Kausmann, Robert; Heiermann, Monika; Rapp, Erdmann; Reichl, Udo; Pühler, Alfred; Klocke, Michael
In: Applied microbiology and biotechnology - Berlin: Springer, Bd. 99 (2015), 18, S. 7791-7803
Dissertation
Mathematical models of influenza A virus infection - from intracellular replication to virus growth in cell populations
Heldt, Frank Stefan; Frensing, Timo; Reichl, Udo
In: Magdeburg, Univ., Fak. für Verfahrens- und Systemtechnik, Diss., 2015, 2014, XX, 190 S., graph. Darst.
Dissertation
Population balance modeling of influenza A virus replication in MDCK cells during vaccine production
Müller, Thomas; Kienle, Achim; Reichl, Udo
In: Magdeburg, Univ., Fak. für Elektrotechnik und Informationstechnik, Diss., 2015, X, 127 S., graph. Darst.
Dissertation
Infection dynamics and virus-induced apoptosis in influenza virus A infected adherent and suspension MDCK cells
Peschel, Britta; Reichl, Udo; Marwan, Wolfgang
In: Zugl.: Magdeburg, Univ., Fak. für Verfahrens- und Systemtechnik, Diss., 2015: Aachen: Shaker, VI, 180 S., Ill., graph. Darst., 21 cm, 291 g - (Forschungsberichte aus dem Max-Planck-Institut für Dynamik komplexer technischer Systeme; 44)
2014
Aufsatz
Sample prefractionation with liquid isoelectric focusing enables in depth microbial metaproteome analysis of mesophilic and thermophilic biogas plants
Kohrs, Fabian; Heyer, Robert; Magnussen, A.; Benndorf, Dirk; Muth, Thilo; Behne, Alexander; Rapp, Erdmann; Kausmann, Robert; Heiermann, Monika; Klocke, Michael; Reichl, Udo
In: Anaerobe - London : Academic Press, Bd. 29 (2014), S. 59-67
Aufsatz
Impact of cultivation conditions on N-glycosylation of influenza virus A hemagglutinin produced in MDCK cell culture
Rödig, Jana; Rapp, Erdmann; Bohne, Jana; Kampe, Michael; Kaffka, Helene; Bock, Andreas; Genzel, Yvonne; Reichl, Udo
In: Biotechnology & bioengineering - New York, NY [u.a.] : Wiley, Bd. 110 (2014), Heft 6, S. 1691-1703
Begutachteter Zeitschriftenartikel
Avidity of influenza virus: Model-based identification of adsorption kinetics from surface plasmon resonance experiments
Wang, Wenjing; Wolff, Michael W.; Reichl, Udo; Sundmacher, Kai
In: Journal of chromatography / A - New York, NY [u.a.]: Science Direct, Bd. 1326.2014, S. 125-129
Begutachteter Zeitschriftenartikel
Flow cytometric viability assessment of lactic acid bacteria starter cultures produced by fluidized bed drying
Bensch, Gerald; Rüger, Marc; Wassermann, Magdalena; Weinholz, Susann; Reichl, Udo; Cordes, Christiana
In: Applied microbiology and biotechnology - Berlin: Springer, Bd. 98.2014, 11, S. 4897-4909
Begutachteter Zeitschriftenartikel
Production of high-titer human influenza A virus with adherent and suspension MDCK cells cultured in a single-use hollow fiber bioreactor
Tapia Delgado, Felipe Ignacio; Vogel, Thomas; Genzel, Yvonne; Behrendt, Ilona; Hirschel, Mark; Gangemi, J. David; Reichl, Udo
In: Vaccine - Amsterdam: Elsevier, 1983, Bd. 32.2014, 8, S. 1003-1011
Begutachteter Zeitschriftenartikel
Vaccine production - upstream processing with adherent or suspension cell lines
Genzel, Yvonne; Rödig, Jana; Rapp, Erdmann; Reichl, Udo
In: Animal Cell Biotechnology , 3rd ed. 2014 - Totowa, NJ : Humana Press , 2014, S. 371-393 - (Methods in Molecular Biology, Methods and Protocols; 1104)
Begutachteter Zeitschriftenartikel
Changes in intracellular metabolite pools during growth of adherent MDCK cells in two different media
Rehberg, M.; Rath, A.; Ritter, J. B.; Genzel, Y.; Reichl, Udo
In: Applied microbiology and biotechnology - Berlin: Springer, Bd. 98.2014, 1, S. 385-397
Begutachteter Zeitschriftenartikel
Impact of defective interfering particles on virus replication and antiviral host response in cell culture-based influenza vaccine production
Frensing, Timo; Pflugmacher, Antje; Bachmann, Mandy; Peschel, Britta; Reichl, Udo
In: Applied microbiology and biotechnology - Berlin: Springer, 1975, Bd. 98.2014, 21, S. 8999-9008
Begutachteter Zeitschriftenartikel
Glycolysis is governed by growth regime and simple enzyme regulation in adherent MDCK cells
Rehberg, Markus; Ritter, Joachim B.; Reichl, Udo
In: PLoS Computational Biology: a new community journal - San Francisco, Calif: Public Library of Science, Vol. 10.2014, 10, Art. e1003885, insgesamt 16 S.
Begutachteter Zeitschriftenartikel
Biological methanation of hydrogen within biogas plants - a model-based feasibility study
Bensmann, Astrid; Hanke-Rauschenbach, R.; Heyer, Robert; Kohrs, Fabian; Benndorf, Dirk; Reichl, Udo; Sundmacher, Kai
In: Applied energy - Amsterdam [u.a.]: Elsevier Science, Bd. 134 (2014), S. 413-425
Begutachteter Zeitschriftenartikel
A flow-through chromatography process for influenza A and B virus purification
Weigel, Thomas; Solomaier, Thomas; Peuker, Alessa; Pathapati, Trinath; Wolff, Michael W.; Reichl, Udo
In: Journal of virological methods - Amsterdam [u.a.]: Elsevier Science, Bd. 207.2014, S. 45-53
Begutachteter Zeitschriftenartikel
The avian cell line AGE1.CR.pIX characterized by metabolic flux analysis
Lohr, Verena; Hädicke, Oliver; Genzel, Yvonne; Jordan, Ingo; Büntemeyer, Heino; Klamt, Steffen; Reichl, Udo
In: BMC biotechnology - London: BioMed Central, Vol. 14.2014, Art. 72 insgesamt 14 S.
Begutachteter Zeitschriftenartikel
Comparative performance of four methods for high-throughput glycosylation analysis of immunoglobulin G in genetic and epidemiological
Huffman, Jennifer E.; Pučić-Baković, Maja; Klarić, Lucija; Hennig, René; Selman, Maurice H. J.; Vučković, Frano; Novokmet, Mislav; Krištić, Jasminka; Borowiak, Matthias; Muth, Thilo; Polašek, Ozren; Razdorov, Genadij; Gornik, Olga; Plomp, Rosina; Theodoratou, Evropi; Wright, Alan F.; Rudan, Igor; Hayward, Caroline; Campbell, Harry; Deelder, André M.; Reichl, Udo; Aulchenko, Yurii S.; Rapp, Erdmann; Wuhrer, Manfred; Lauc, Gordan
In: Molecular & cellular proteomics: MCP - Bethesda, Md: The American Society for Biochemistry and Molecular Biology, Bd. 13.2014, S. 1598-1610
Begutachteter Zeitschriftenartikel
High cell density cultivations by alternating tangential flow (ATF) perfusion for influenza A virus production using suspension cells
Genzel, Yvonne; Vogel, Thomas; Buck, Johannes; Behrendt, Ilona; Vázquez Ramírez, Daniel; Schiedner, Gudrun; Jordan, Ingo; Reichl, Udo
In: Vaccine - Amsterdam: Elsevier, Bd. 32 (2014), 24, S. 2770-2781
Begutachteter Zeitschriftenartikel
Species-specific viability analysis of Pseudomonas aeruginosa, Burkholderia cepacia and Staphylococcus aureus in mixed culture by flow cytometry
Rüger, Marc; Ackermann, Mandy; Reichl, Udo
In: BMC microbiology - London: BioMed Central, Bd. 14.2014, Art. 56, insgesamt 15 S.
Begutachteter Zeitschriftenartikel
The influence of cell growth and enzyme activity changes on intracellular metabolite dynamics in AGE1.HN.AAT cells
Rath, Alexander; Rehberg, Markus; Janke, Robert; Genzel, Yvonne; Scholz, Sebastian; Noll, Thomas; Rose, Thomas; Sandig, Volker; Reichl, Udo
In: Journal of biotechnology - Amsterdam [u.a.]: Elsevier Science, Bd. 178.2014, S. 43-53
Dissertation
Characterization of the avian designer cells AGE1.CR and AGE1.CR.plX considering growth, metabolism and production of influenza virus and Modified Vaccinia Virus Ankara (MVA)
Lohr, Verena; Reichl, Udo
In: Magdeburg, Univ., Fak. für Verfahrens- und Systemtechnik, Diss., 2014, IX, 178 S., Ill., graph. Darst., 30 cm
Dissertation
Impact of cultivation conditions on N-glycosylation of influenza A virus hemagglutinin, on quasispecies composition, and on immunogenicity of virus preparations
Rödig, Jana Verena; Reichl, Udo
In: Magdeburg, Univ., Fak. für Verfahrens- und Systemtechnik, Diss., 2014, XVII, 159, S44 Bl., graph. Darst.
Habilitation
Improving industrial antibody manufacturing processes using animal cell culture technology
Pohlscheidt, Michael; Reichl, Udo
In: Magdeburg, Univ., Fak. für Verfahrens- und Systemtechnik, Habil.-Schr., 2014, Getr. Zählung, Ill., graph. Darst., 30 cm
Herausgeberschaft
Large-Scale Networks in Engineering and Life Sciences
Benner, Peter; Findeisen, Rolf; Flockerzi, Dietrich; Reichl, Udo; Sundmacher, Kai
In: Cham: Birkhäuser, 2014, Online-Ressource (XIV, 388 p. 111 illus., 63 illus. in color, online resource) - (Modeling and Simulation in Science, Engineering and Technology; SpringerLink; Bücher; Springer eBook Collection; Mathematics and Statistics), ISBN: 978-3-319-08437-4
2013
Aufsatz
Distributed modeling of human influenza a virus–host cell interactions during vaccine production
Müller, Thomas; Dürr, Robert; Isken, Britta; Schulze-Horsel, Josef; Reichl, Udo; Kienle, Achim
In: Biotechnology & bioengineering - New York, NY [u.a.] : Wiley, Bd. 110 (2013), Heft 8, S. 2252-2266
Aufsatz
Metaproteome analysis of the microbial communities in agricultural biogas plants
Heyer, Robert; Kohrs, Fabian; Benndorf, Dirk; Rapp, Erdmann; Kausmann, Robert; Heiermann, Monika; Klocke, Michael; Reichl, Udo
In: New biotechnology - New York, NY [u.a.] : Elsevier, Bd. 30 (2013), Heft 6, S. 614-622
Begutachteter Zeitschriftenartikel
CAP, a new human suspension cell line for influenza virus production
Genzel, Yvonne; Behrendt, Ilona; Rödig, Jana; Rapp, Erdmann; Kueppers, Claudia; Kochanek, Stefan; Schiedner, Gudrun; Reichl, Udo
In: Applied microbiology and biotechnology - Berlin: Springer, Bd. 97 (2013), 1, S. 111-122, 2012
Begutachteter Zeitschriftenartikel
Multiscale modeling of influenza A virus infection supports the development of direct-acting antivirals
Heldt, Frank S.; Frensing, Timo; Pflugmacher, Antje; Gröpler, Robin; Peschel, Britta; Reichl, Udo
In: PLoS Computational Biology: a new community journal/ Public Library of Science - San Francisco, Calif.: Public Library of Science, 2005, Bd. 9.2013, 11, Art. e1003372, insges. 13 S.
Begutachteter Zeitschriftenartikel
Proteomics in environmental and technical microbiology
Benndorf, Dirk; Reichl, Udo
In: Engineering in life sciences - Weinheim: Wiley-VCH, 2001, Bd. 14.2013, 1, S. 27-46
Begutachteter Zeitschriftenartikel
Evaluating differences of metabolic performances - statistical methods and their application to animal cell cultivations
Hädicke, O.; Lohr, V.; Genzel, Y.; Reichl, Udo; Klamt, S.
In: Biotechnology & bioengineering. - New York, NY [u.a.] : Wiley, Bd. 110.2013, 10, S. 2633-2642
Begutachteter Zeitschriftenartikel
Comparison of influenza virus yields and apoptosis-induction in an adherent and a suspension MDCK cell line
Peschel, B.; Frentzel, S.; Laske, T.; Genzel, Y.; Reichl, Udo
In: Vaccine. - Amsterdam : Elsevier, Bd. 31.2013, 48, S. 5693-5699
Begutachteter Zeitschriftenartikel
Batch-to-batch variability of two human designer cell lines - AGE1.HN and AGE1.HN.AAT ; carried out by different laboratories under defined culture conditions using a mathematical model
Freund, Susann; Rath, Alexander; Barradas, Oscar Platas; Skerhutt, Eva; Scholz, Sebastian; Niklas, Jens; Sandig, Volker; Rose, Thomas; Heinzle, Elmar; Noll, Thomas; Pörtner, Ralf; Zeng, An-Ping; Reichl, Udo
In: Engineering in life sciences - Weinheim: Wiley-VCH, 2001, Bd. 13.2013, 6, S. 580-592
Begutachteter Zeitschriftenartikel
Elements in the development of a production process for modified vaccinia virus ankara
Jordan, Ingo; Lohr, Verena; Genzel, Yvonne; Reichl, Udo; Sandig, Volker
In: Microorganisms. - Basel : MDPI, Bd. 1.2013, 1, S. 100-121
Begutachteter Zeitschriftenartikel
PPARα and fatty acid oxidation mediate glucocorticoid resistance in chronic lymphocytic leukemia
Tung, Stephanie; Shi, Yonghong; Wong, Karry; Zhu, Fang; Gorczynski, Reg; Laister, Robert C.; Minden, Mark; Blechert, Anne-Kareen; Genzel, Yvonne; Reichl, Udo; Spaner, David E.
In: Blood. - Stanford, Calif : HighWire Press, Bd. 112.2013, 6, S. 969-980
Begutachteter Zeitschriftenartikel
Continuous influenza virus production in cell culture shows a periodic accumulation of defective interfering particles
Frensing, Timo; Stefan, Frank; Pflugmacher, Antje; Behrendt, Ilona; Jordan, Ingo; Flockerzi, Dietrich; Genzel, Yvonne; Reichl, Udo
In: PLOS ONE - San Francisco, California, US: PLOS, 2006, Vol. 8.2013, 9, Art. e72288, insgesamt 9 S.
Begutachteter Zeitschriftenartikel
Development of a high-throughput glycoanalysis method for the characterization of oligosaccharides in human milk utilizing multiplexed capillary gel electrophoresis with laser-induced fluorescence detection
Kottler, Robert; Mank, Marko; Hennig, René; Müller-Werner, Beate; Stahl, Bernd; Reichl, Udo; Rapp, Erdmann
In: Electrophoresis. - Weinheim : Wiley-Blackwell, Bd. 34.2013, 16, S. 2323-2336
Begutachteter Zeitschriftenartikel
glyXalign - high-throughput migration time alignment preprocessing of electrophoretic data retrieved via multiplexed capillary gel electrophoresis with laser-induced fluorescence detection-based glycoprofiling
Behne, Alexander; Muth, Thilo; Borowiak, Matthias; Reichl, Udo; Rapp, Erdmann
In: Electrophoresis. - Weinheim : Wiley-Blackwell, Bd. 34.2013, 16, S. 2311-2315
Begutachteter Zeitschriftenartikel
Continuous purification of influenza virus using simulated moving bed chromatography
Kröber, T.; Wolff, M. W.; Hundt, B.; Seidel-Morgenstern, Andreas; Reichl, Udo
In: Journal of chromatography / A - New York, NY [u.a.]: Science Direct, Bd. 1307 (2013), S. 99-110
Begutachteter Zeitschriftenartikel
Metagenome and metaproteome analyses of microbial communities in mesophilic biogas-producing anaerobic batch fermentations indicate concerted plant carbohydrate degradation
Hanreich, Angelika; Schimpf, Ulrike; Zakrzewski, Martha; Schlüter, Andreas; Benndorf, Dirk; Heyer, Robert; Rapp, Erdmann; Pühler, Alfred; Reichl, Udo; Klocke, Michael
In: Systematic and applied microbiology - München: Elsevier, Bd. 36 (2013), 5, S. 330-338
Begutachteter Zeitschriftenartikel
Identification of growth phases and influencing factors in cultivation of AGE1.HN cells using set-based methods
Borchers, Steffen; Freund, Susann; Rath, Alexander; Streif, Stefan; Reichl, Udo; Findeisen, Rolf
In: PLOS ONE - San Francisco, California, US: PLOS, 2006, Vol. 8.2013, 8, Art. e68124, insgesamt 11 S.
Begutachteter Zeitschriftenartikel
Proteome analysis of virushost cell interaction - rabies virus replication in Vero cells in two different media
Pech, Sabine; Rourou, Samia; Vester, Diana; Majoul, Samy; Benndorf, Dirk; Genzel, Yvonne; Rapp, Erdmann; Kallel, Héla; Reichl, Udo
In: Applied microbiology and biotechnology - Berlin: Springer, Bd. 97 (2013), 12, S. 5493-5506
Begutachteter Zeitschriftenartikel
Searching for a needle in a stack of needles: challenges in metaproteomics data analysis
Muth, Thilo; Benndorf, Dirk; Reichl, Udo; Rapp, Erdmann; Martens, Lennart
In: Molecular BioSystems - Cambridge: Royal Society of Chemistry, Bd. 9 (2013), 4, S. 578-585
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