Publikationen

2020

Begutachteter Zeitschriftenartikel

Lowinus, Theresa;  Bose, Tanima;  Simeoni, Luca;  Schraven, Burkhart;  Bommhardt, Ursula 

Kv1.3 potassium channels - promising therapeutic targets in hematological malignancies
In: Journal of cellular signaling - Wilmington: Scientific Archives LLC, 2020, Bd. 1.2020, 3, S. 79-86

Publikationslink

2019

Begutachteter Zeitschriftenartikel

Bommhardt, Ursula;  Schraven, Burkhart;  Simeoni, Luca 

Beyond TCR signaling - emerging functions of Lck in cancer and immunotherapy
In: International journal of molecular sciences - Basel: Molecular Diversity Preservation International, Bd. 20.2019, 14, Art.-Nr. 3500, insges. 18 S.

Publikationslink

Lowinus, Theresa;  Heidel, Florian;  Bose, Tanima;  Nimmagadda, Subbaiah Chary;  Schnöder, Tina;  Cammann, Clemens;  Schmitz, Ingo;  Seifert, Ulrike;  Fischer, Thomas;  Schraven, Burkhart;  Bommhardt, Ursula 

Memantine potentiates cytarabine-induced cell death of acute leukemia correlating with inhibition of Kv1.3 potassium channels, AKT and ERK1/2 signaling
In: Cell communication and signaling - London: Biomed Central, Bd. 17.2019, Art.-Nr. 5, insges. 13 S.

Publikationslink

2018

Begutachteter Zeitschriftenartikel

Rheinländer, Andreas;  Schraven, Burkhart;  Bommhardt, Ursula 

CD45 in human physiology and clinical medicine
In: Immunology letters - Amsterdam [u.a.]: Elsevier Science, Bd. 196.2018, S. 22-32

Publikationslink

2017

Abstract

Mirdamadi, Yasaman Sadat;  Thielitz, Anja;  Goihl, Alexander;  Guttek, Karina;  Zouboulis, Christos C.;  Reinhold, Dirk;  Bommhardt, Ursula;  Quist, Sven Roy;  Gollnick, Harald 

Insights into the mechanism of action of insulin-like growth factor-1 and insulin in human T cells in vitro
In: Experimental dermatology: the official journal of the European Immunodermatology Society - Oxford: Wiley-Blackwell, Bd. 26.2017, 3, P081 (OP06/06), S. E35

Publikationslink

Mirdamadi, Yasaman Sadat;  Thielitz, Anja;  Wiede, Antje;  Goihl, Alexander;  Zouboulis, Christos C.;  Reinhold, Dirk;  Bommhardt, Ursula;  Quist, Sven Roy;  Gollnick, Harald 

Insights into the mechanism of action of isotretinoin in human sebocytes in vitro
In: Experimental dermatology: the official journal of the European Immunodermatology Society - Oxford: Wiley-Blackwell, Bd. 26.2017, 3, P082, S. E35-E36

Publikationslink

Begutachteter Zeitschriftenartikel

Mirdamadi, Yasaman Sadat;  Thielitz, Anja;  Wiede, Antje;  Goihl, Alexander;  Zouboulis, Christos C.;  Bommhardt, Ursula;  Quist, Sven Roy;  Gollnick, Harald 

Effects of isotretinoin on the phosphoinositide-3-kinase/Akt/FoxO1 pathway and molecular functions of SZ95 sebocytes in vitro
In: Journal of clinical & experimental dermatology research - Los Angeles, CA: Omics international, Bd. 8.2017, 3, Art.-Nr. 1000399, insges. 12 S.

Publikationslink

Mirdamadi, Yasaman Sadat;  Bommhardt, Ursula;  Goihl, Alexander;  Guttek, Karina;  Zouboulis, Christos C.;  Quist, Sven Roy;  Gollnick, Harald 

Insulin and insulin-like growth factor-1 can activate the phosphoinositide-3-kinase /Akt/FoxO1 pathway in T cells in vitro
In: Dermato-endocrinology - Austin, Tex: Landes Bioscience, Bd. 9.2017, Art.-Nr. e1356518, insges. 13 S.

Publikationslink

2016

Begutachteter Zeitschriftenartikel

Lowinus, Theresa;  Bose, Tanima;  Busse, Stefan;  Busse, Mandy;  Reinhold, Dirk;  Schraven, Burkhart;  Bommhardt, Ursula H. H. 

Immunomodulation by memantine in therapy of Alzheimer's disease is mediated through inhibition of Kv1.3 channels and T cell responsiveness
In: OncoTarget - [S.l.]: Impact Journals LLC, 2010, Bd. 7.2016, 33, S. 53797-53807

Publikationslink

2015

Abstract

Mirdamadi, Yasaman Sadat;  Thielitz, Anja;  Wiede, Antje;  Goihl, Alexander;  Zouboulis, Christos C.;  Reinhold, Dirk;  Bommhardt, Ursula;  Quist, Sven Roy;  Gollnick, Harald 

Effects of isotretinoin on FoxO1 transcriptional regulation and molecular functions of SZ95 sebocytes
In: Experimental dermatology: the official journal of the European Immunodermatology Society - Oxford: Wiley-Blackwell, Bd. 24.2015, 3, P068, S. E12

Publikationslink

Begutachteter Zeitschriftenartikel

Mirdamadi, Yasaman Sadat;  Thielitz, Anja;  Wiede, Antje;  Goihl, Alexander;  Papakonstantinou, Eleni;  Hartig, Roland;  Zouboulis, Christos C.;  Reinhold, Dirk;  Simeoni, Luca;  Bommhardt, Ursula;  Quist, Sven Roy;  Gollnick, Harald 

Insulin and insulin-like growth factor-1 can modulate the phosphoinositide-3-kinase/Akt/FoxO1 pathway in SZ95 sebocytes in vitro
In: Molecular and cellular endocrinology - Amsterdam [u.a.]: Elsevier Science, Bd. 415 (2015), S. 32-44

Publikationslink

Linker, Ralf;  Lee, De-Hyung;  Flach, Anne-Christine;  Litke, Tanja;  Brandt, Jens;  Reichardt, Holger Michael;  Lingner, Thomas;  Bommhardt, Ursula;  Sendtner, Michael;  Gold, Ralf;  Flügel, Alexander;  Lühder, Fred 

Thymocyte-derived BDNF influences T-cell maturation at the DN3/DN4 transition stage
In: European journal of immunology - Weinheim: Wiley-VCH, Bd. 45.2015, 5, S. 1326-1338

Publikationslink

Busse, Stefan;  Steiner, Johann;  Glorius, Sarah;  Dobrowolny, Henrik;  Greiner-Bohl, Sabrina;  Mawrin, Christian;  Bommhardt, Ursula;  Hartig, Roland;  Bogerts, Bernhard;  Busse, Mandy 

VGF expression by T lymphocytes in patients with Alzheimer's disease
In: OncoTarget - [S.l.]: Impact Journals LLC, 2010, Bd. 6.2015, 17, S. 14843-14851

Publikationslink

2014

Abstract

Lühder, Fred;  Linker, Ralf;  Lee, De-Hyung;  Reichardt, Holger Michael;  Bommhardt, Ursula;  Gold, Ralf;  Flügel, Alexander 

Critical role of thymocyte-derived brain-derived neurotrophic factor in T cell maturation
In: Journal of neuroimmunology: official journal of the International Society for Neuroimmunology - Amsterdam [u.a.]: Elsevier Science, 1981, Bd. 275.2014, 1/2, S. 202-203

Publikationslink

Begutachteter Zeitschriftenartikel

Busse, Stefan;  Steiner, Johann;  Micheel, Justus;  Dobrowolny, Henrik;  Mawrin, Christian;  Krause, Tim Johannes;  Adamaszek, Michael;  Bogerts, Bernhard;  Bommhardt, Ursula;  Hartig, Roland;  Busse, Mandy 

Age-related increase of VGF-expression in T lymphocytes
In: Aging - [S.l.]: Impact Journals, LLC, 2009, Bd. 6.2014, 6, S. 440-453

Publikationslink

Kahlfuß, Sascha;  Simma, Narasimhulu;  Mankiewicz, Judith;  Bose, Tanima;  Lowinus, Theresa;  Klein-Heßling, Stefan;  Sprengel, Rolf;  Schraven, Burkhart;  Heine, Martin;  Bommhardt, Ursula 

Immunosuppression by N-Methyl-D-aspartate receptor antagonists is mediated through inhibition of Kv1.3 and KCa3.1 channels in T cells
In: Molecular and cellular biology - Washington, DC: Soc, 1981, Bd. 34.2014, 5, S. 820-831

Publikationslink

Simma, Narasimhulu;  Bose, Tanima;  Kahlfuß, Sascha;  Mankiewicz, Judith;  Lowinus, Theresa;  Lühder, Fred;  Schüler, Thomas;  Schraven, Burkhart;  Heine, Martin;  Bommhardt, Ursula 

NMDA-receptor antagonists block B-cell function but foster IL-10 production in BCR/CD40-activated B cells
In: Cell communication and signaling - London: Biomed Central, 2003, Bd. 12.2014, Art.-Nr. 75, insges. 13 S.

Publikationslink

Dissertation

Bose, Tanima;  Bommhardt, Ursula [Gutachter] 

Crosstalk between NMDAR antagonists and potassium channels in murine and human lymphocytes
In: Magdeburg, Univ., Fak. für Naturwiss., Diss., 2014, 92 Bl., graph. Darst., 30 cm

2013

Abstract

Patra, Amiya K.;  Avots, Andris;  Zahedi, René P.;  Schüler, Thomas;  Sickmann, Albert;  Bommhardt, Ursula;  Serfling, Edgar 

Interleukin-7-mediated NFAT activation sets the threshold for T cell development
In: Cytokine. - London : Academic Press; Bd. 63.2013, 3, Abs. 196, S. 289

Publikationslink

Begutachteter Zeitschriftenartikel

Patra, Amiya Kumar;  Avots, Andris;  Zahedi, René Peiman;  Schüler, Thomas;  Sickmann, Albert;  Bommhardt, Ursula;  Serfling, Edgar 

An alternative NFAT-activation pathway mediated by IL-7 is critical for early thymocyte development
In: Nature immunology - New York, NY: SpringerNature, Bd. 14.2013, 2, S. 127-135

Publikationslink

2012

Dissertation

Pierau, Mandy;  Bommhardt, Ursula [Gutachter] 

Proteinkinase B- und TGFβ1-Signalwege - Untersuchungen zu ihrer Interaktion bei der Th-Zelldifferenzierung
In: Magdeburg, Univ., Fak. für Naturwiss., Diss., 2012, 143 Bl., graph. Darst.

Originalartikel in begutachteter internationaler Zeitschrift

Pierau, Mandy;  Na, Shin-Young;  Simma, Narasimhulu;  Lowinus, Theresa;  Marx, Alexander;  Schraven, Burkhart;  Bommhardt, Ursula H. 

Constitutive Akt1 signals attenuate B-cell receptor signaling and proliferation, but enhance B-cell migration and effector function
In: European journal of immunology - Weinheim: Wiley, Bd. 42 (2012), 12, S. 3381-3393

Publikationslink

2011

Dissertation

Engelmann, Swen;  Bommhardt, Ursula [Gutachter] 

Einfluss von Proteinkinase B (PKB/Akt) auf Differenzierungsprozesse von T-Helferzellen und den Verlauf der Experimentellen Autoimmunen Enzephalomyelitis (EAE)
In: Magdeburg, Univ., Fak. für Naturwiss., Diss., 2011, III, 104 Bl., graph. Darst., 30 cm

Originalartikel in begutachteter internationaler Zeitschrift

Bhattacharyya, Sankar;  Deb, Jolly;  Patra, Amiya Kumar;  Pham, Duong Anh Thuy;  Chen, Wen;  Väth, Martin;  Berberich-Siebelt, Friederike;  Klein-Heßling, Stefan;  Lamperti, Edward D.;  Reifenberg, Kurt;  Jellúšová, Júlia;  Schweizer, Astrid;  Nitschke, Lars;  Leich, Ellen;  Rosenwald, Andreas;  Brunner, Cornelia;  Engelmann, Swen;  Bommhardt, Ursula;  Avots, Andris;  Müller, Martin R.;  Kondo, Eisaku;  Serfling, Edgar 

NFATc1 affects mouse splenic B cell function by controlling the calcineurin-NFAT signaling network
In: The journal of experimental medicine <New York, NY> - New York, NY: Rockefeller Univ. Press, 1896, Bd. 208.2011, 4, S. 823-839

Publikationslink

2010

Dissertation

Drewes, Thomas;  Bommhardt, Ursula [Gutachter] 

Cross-talk of protein kinase B (PKB/Akt) with the transcription factor NFAT and the Src kinase Fyn in T lymphocytes
In: Magdeburg, Univ., Fak. für Naturwiss., Diss., 2010, III, 116 Bl., graph. Darst., 30 cm

Originalartikel in begutachteter internationaler Zeitschrift

Bommhardt, Ursula 

Hedgehog signalling in T-cell development: A non-redundant role for Gli1
In: Cell cycle . - Georgetown, Tex. : Landes Bioscience, Bd. 9.2010, 22, S. 4428

Publikationslink

Bommhardt, Ursula 

Hedgehog signalling in T-cell development: A non-redundant role for Gli1.
In: Cell Cycle. 2010 Nov 15;9(22):4433-4432.

2009

Originalartikel in begutachteter internationaler Zeitschrift

Bajbouj, Khuloud;  Pöhlmann, Angela;  Küster, Dörthe;  Drewes, Thomas;  Haase, Kathrin;  Hartig, Roland;  Teller, Anne;  Kliche, Stefanie;  Walluscheck, Diana;  Ivanovska, Jelena;  Chakilam, Saritha;  Ulitzsch, Annika;  Bommhardt, Ursula;  Leverkus, Martin;  Roessner, Albert;  Schneider-Stock, Regine 

Identification of phosphorylated p38 as a novel DAPK-interacting partner during TNF[alpha]-induced apoptosis in colorectal tumor cells
In: The American journal of pathology . - Bethesda, Md. : American Society for Investigative Pathology, Bd. 175.2009, 2, S. 557-570

Publikationslink

Pierau, Mandy;  Engelmann, Swen;  Reinhold, Dirk;  Lapp, Thabo;  Schraven, Burkhart;  Bommhardt, Ursula 

Protein kinase B/Akt signals impair Th17 differentiation and support natural regulatory T cell function and induced regulatory T cell formation
In: The journal of immunology . - Bethesda, Md. : American Assoc. of Immunologists, Bd. 183.2009, 10, S. 6124-6134

Publikationslink

2008

Originalartikel in begutachteter internationaler Zeitschrift

Bekeredjian-Ding, Isabelle;  Doster, Anne;  Schiller, Martin;  Heyder, Petra;  Lorenz, Hanns-Martin;  Schraven, Burkhart;  Bommhardt, Ursula;  Heeg, Klaus 

TLR9-activating DNA up-regulates ZAP70 via sustained PKB induction in IgM+ B cells
In: The journal of immunology: official journal of the American Association of Immunologists - Rockville, Md.: American Association of Immunologists, 1916, Bd. 181.2008, 12, S. 8267-8277

2007

Originalartikel in begutachteter internationaler Zeitschrift

Sáez Rodríguez, Julio;  Simeoni, Luca;  Lindquist, Jonathan A.;  Hemenway, Rebecca;  Bommhardt, Ursula;  Arndt, Börge;  Haus, Utz-Uwe;  Weismantel, Robert;  Gilles, Ernst D.;  Klamt, Steffen;  Schraven, Burkhart 

A logical model provides insights into T cell receptor signaling
In: PLoS Computational Biology - San Francisco, Calif: Public Library of Science, Bd. 3(2007), 8, insges. 11 S.

Publikationslink

Bommhardt, Ursula 

Glis: novel modulators of TCR signaling?
In: Blood: the journal of hematology - Washington, DC: American Society of Hematology, Bd. 109.2007, 9, S. 3618-3619

Publikationslink

Masse, Guillemette X.;  Corcuff, Erwan;  Decaluwe, Hélène;  Bommhardt, Ursula;  Lantz, Olivier;  Buer, Jan;  DiSanto, James P. 

[Gamma]c cytokines provide multiple homeostatic signals to naive CD4+ T cells
In: European journal of immunology - Weinheim: Wiley VCH, Bd. 37.2007, 9, S. 2606-2616

Publikationslink

2006

Originalartikel in begutachteter internationaler Zeitschrift

Patra, Amiya Kumar;  Drewes, Thomas;  Engelmann, Swen;  Chuvpilo, Sergei;  Kishi, Hiroyuki;  Hünig, Thomas;  Serfling, Edgar;  Bommhardt, Ursula H. 

PKB rescues Calcineurin/NFAT-induced arrest of Rag expression and Pre-T cell differentiation
In: The journal of immunology: official journal of the American Association of Immunologists - Rockville, Md.: American Association of Immunologists, 1916, Bd. 177.2006, 7, S. 4567-4576

Publikationslink

Letzte Änderung: 01.09.2020 - Ansprechpartner: Webmaster