Publikationen
2025
Neuropathic pain and distinct CASPR2 autoantibody IgG subclasses drive neuronal hyperexcitability
Habib, Margarita; Wießler, Anna-Lena; Fischer, Patrik; Niesner, Michéle G.; Pauls-Selcho, Mareike; Abrante Cabrera, Ligia; Werner, Christian; Sodmann, Annemarie; Koch, Maximilian; Zare, Abdolhossein; Prüß, Harald; Dargvainiene, Justina; Lewerenz, Jan; Handreka, Robert; Körtvélyessy, Péter; Reinhold, Dirk; Thaler, Franziska; Pitarokoili, Kalliopi; Kittel, Robert Johannes; Briese, Michael; Sendtner, Michael; Rittner, Heike; Leypoldt, Frank; Sommer, Claudia; Blum, Robert; Doppler, Kathrin Janina; Villmann, Carmen
In: Neurology: Neuroimmunology & Neuroinflammation ; official journal of the American Academy of Neurology - Philadelphia, Pa. : Wolters Kluwer, Bd. 12 (2025), Heft 4, Artikel e200423, insges. 13 S.
2024
Why a pinch of zinc in liver disease matters
Grüngreiff, Kurt; Reinhold, Dirk; Maret, Wolfgang
In: Annals of hepatology - México : Assoc., Bd. 29 (2024), Heft 1, Artikel 101152, insges. 2 S.
Targeting type I DED interactions at the DED filament serves as a sensitive switch for cell fate decisions
König, Corinna; Ivanisenko, Nikita V.; Hillert-Richter, Laura Katharina; Namjoshi, Deepti; Natu, Kalyani; Espe, Johannes; Reinhold, Dirk; Kolchanov, Nikolai A.; Ivanisenko, Vladimir A.; Kähne, Thilo; Bose, Kakoli; Lavrik, Inna N.
In: Cell chemical biology - Amsterdam : Elsevier, Bd. 31 (2024), Heft 11, S. 1969-1985, insges. 24 S.
Proteomic and transcriptomic profiling of brainstem, cerebellum and olfactory tissues in early- and late-phase COVID-19
Radke, Josefine; Meinhardt, Jenny; Aschman, Tom; Chua, Robert Lorenz; Farztdinov, Vadim; Lukassen, Sören; Ten, Foo Wei; Friebel, Ekaterina; Ishaque, Naveed; Franz, Jonas; Huhle, Valerie Helena; Mothes, Ronja; Peters, Kristin; Thomas, Carolina; Schneeberger, Shirin; Schumann, Elisa; Kawelke, Leona; Jünger, Julia; Horst, Viktor; Streit, Simon; Manitius, Regina; Körtvélyessy, Péter; Vielhaber, Stefan; Reinhold, Dirk; Hauser, Anja Erika; Osterloh, Anja; Enghard, Philipp; Ihlow, Jana; Elezkurtaj, Sefer; Horst, David; Kurth, Florian Michael; Müller, Marcel Alexander; Gassen, Nils C.; Melchert, Julia; Jechow, Katharina; Timmermann, Bernd; Fernandez-Zapata, Camila; Böttcher, Chotima; Stenzel, Werner; Krüger, Elke Helene; Landthaler, Markus; Wyler, Emanuel; Corman, Victor Max; Stadelmann, Christine; Ralser, Markus; Eils, Roland; Heppner, Frank L.; Mülleder, Michael; Conrad, Christian; Radbruch, Helena
In: Nature neuroscience - New York, NY : Nature America, Bd. 27 (2024), Heft 3, S. 409-420, insges. 32 S.
Leucine-rich glioma-inactivated 1 (LGI1) protein stimulates proliferation and IL-10 production in peripheral blood mononuclear cells of patients with LGI1 antibody-mediated autoimmune encephalitis in vitro
Goihl, Alexander; Reinhold, Dirk; Reinhold, Annegret; Schraven, Burkhart; Körtvélyessy, Péter
In: International journal of molecular sciences - Basel : Molecular Diversity Preservation International, Bd. 25 (2024), Heft 5, Artikel 2581, insges. 8 S.
Targeting caspase-8/c-FLIPL heterodimer in complex II promotes DL-mediated cell death
Hillert-Richter, Laura Katharina; König, Corinna; Ivanisenko, Nikita V.; Reinhold, Dirk; Lavrik, Inna N.
In: Frontiers in cell and developmental biology - Lausanne : Frontiers Media, Bd. 12 (2024), Artikel 1471216, insges. 16 S.
2023
Patterns of allergic sensitization in adults with severe asthma - the ATLAS non-interventional study
Lücke, Eva Kristin; Schraven, Burkhart; Borucki, Katrin; Lux, Anke; Reinhold, Dirk; Wu, Qingyu; Schreiber, Jens
In: Journal of asthma - Philadelphia, Pa. : Taylor & Francis, Bd. 60 (2023), Heft 11, S. 2021-2029
The brain reacting to COVID-19 - analysis of the cerebrospinal fluid proteome, RNA and inflammation
Reinhold, Dirk; Farztdinov, Vadim; Yan, Yan; Meisel, Christian; Sadlowski, Henrik; Kühn, Joachim; Perschel, Frank H.; Endres, Matthias; Düzel, Emrah; Vielhaber, Stefan; Guttek, Karina; Goihl, Alexander; Venø, Morten; Teegen, Bianca; Stöcker, Winfried; Stubbemann, Paula; Kurth, Florian Michael; Sander, Leif Erik; Ralser, Markus; Otto, Carolin; Streit, Simon; Jarius, Sven; Ruprecht, Klemens; Radbruch, Helena; Kjems, Jørgen; Mülleder, Michael; Heppner, Frank L.; Körtvélyessy, Péter
In: Journal of neuroinflammation - London : BioMed Central, Bd. 20 (2023), Artikel 30, insges. 16 S.
Plasma concentrations of anti-inflammatory cytokine TGF-β are associated with hippocampal structure related to explicit memory performance in older adults
Raschick, Matthias; Richter, Anni; Fischer, Larissa; Knopf, Lea; Schult, Annika; Yakupov, Renat; Behnisch, Gusalija; Guttek, Karina; Düzel, Emrah; Dunay, Ildikò Rita; Seidenbecher, Constanze; Schraven, Burkhart; Reinhold, Dirk; Schott, Björn H.
In: Journal of neural transmission - Wien [u.a.] : Springer, Bd. 130 (2023), Heft 8, S. 989-1002
Allgemeine Kenntnisse zu häufig angewandten Testverfahren in der rheumatologisch-immunologischen Diagnostik und Forschung - General knowledge of frequently applied test procedures in rheumatological and immunological diagnostics and research
Reinhold, Dirk; Reinhold, Annegret; Schraven, Burkhart; Feist, Eugen
In: Zeitschrift für Rheumatologie - Darmstadt : Steinkopff, Bd. 82 (2023), Heft 4, S. 278-284
Zinc aspartate induces proliferation of resting and antigen-stimulated human PBMC under high-density cell culture condition
Guttek, Karina; Reinhold, Annegret; Grüngreiff, Kurt; Schraven, Burkhart; Reinhold, Dirk
In: Journal of trace elements in medicine and biology - München : Elsevier, Bd. 77 (2023), Artikel 127152
Human glycoprotein-2 expressed in Brunner glands - a putative autoimmune target and link between Crohn's and coeliac disease
Roggenbuck, Dirk; Goihl, Alexander; Sowa, Mandy; Lopens, Steffi; Rödiger, Stefan; Schierack, Peter; Conrad, Karsten; Sommer, Ulrich; Jöhrens, Korinna; Grützmann, Robert; Reinhold, Dirk; Laaß, Martin Walter
In: Clinical immunology - San Diego, Calif. : Elsevier, Bd. 247 (2023), Artikel 109214, insges. 12 S.
Antibody properties associate with clinical phenotype in LGI1 encephalitis
Ludewig, Susann; Salzburger, Leonie; Goihl, Alexander; Rohne, Jana; Leypoldt, Frank; Bittner, Daniel Markus; Düzel, Emrah; Schraven, Burkhart; Reinhold, Dirk; Korte, Martin; Körtvélyessy, Péter
In: Cells - Basel : MDPI, Bd. 12 (2023), Heft 2, Artikel 282, insges. 15 S.
2022
IgE-mediated sensitization towards frequent and rare allergens in severe asthmatics - the ATLAS project
Schreiber, Jens; Thurm, Christoph; Reinhold, Dirk; Luecke, Eva; Schraven, Burkhart; Wu, Qingyu; Lux, Anke; Mailänder, Claudia
In: American journal of respiratory and critical care medicine - New York, NY : American Thoracic Society, Bd. 205 (2022), Artikel A5703, insges. 1 S.
Unique lasting effects on immune composition and autoantibody prevalence after mild SARS-CoV-2 infections
Lingel, Holger; Meltendorf, Stefan; Billing, Ulrike; Thurm, Christoph; Vogel, Katrin; Majer, Christiane; Prätsch, Florian; Roggenbuck, Dirk; Heuft, Hans-Gert; Hachenberg, Thomas; Feist, Eugen; Reinhold, Dirk; Brunner-Weinzierl, Monika
In: European journal of immunology - Weinheim : Wiley-VCH, Bd. 52 (2022), Heft Suppl. 1, S. 173-174, Artikel P 028
Homologous and heterologous anti-COVID-19 vaccination does not induce new-onset formation of autoantibodies typically accompanying lupus erythematodes, rheumatoid arthritis, celiac disease and antiphospholipid syndrome
Thurm, Christoph; Reinhold, Annegret; Borucki, Katrin; Kahlfuß, Sascha; Feist, Eugen; Schreiber, Jens; Reinhold, Dirk; Schraven, Burkhart
In: Vaccines - Basel: MDPI, 2013, Bd. 10 (2022), 2, insges. 16 S.
Robust induction of neutralizing antibodies against the SARS-CoV-2 Delta variant after homologous Spikevax or heterologous Vaxzevria-Spikevax vaccination
Hammerschmidt, Swantje Iris Anna-Dorothea; Thurm, Christoph; Bos̆njak, Berislav; Bernhardt, Günter; Reinhold, Annegret; Willenzon, Stefanie; Ritter, Christiane; Reinhold, Dirk; Schraven, Burkhart; Förster, Reinhold
In: European journal of immunology - Weinheim : Wiley-VCH, Bd. 52 (2022), Heft 2, S. 356-359
IL-13 determines specific IgE responses and SARS-CoV-2 immunity after mild COVID-19 and novel mRNA vaccination
Meltendorf, Stefan; Vogel, Katrin; Thurm, Christoph; Prätsch, Florian; Reinhold, Annegret; Färber, Jacqueline; Heuft, Hans-Gert; Kaasch, Achim; Hachenberg, Thomas; Weinzierl, Stefan; Schraven, Burkhart; Reinhold, Dirk; Brunner-Weinzierl, Monika; Lingel, Holger
In: European journal of immunology - Weinheim : Wiley-VCH, Bd. 52 (2022), Heft 12, S. 1972-1979
Ionic mitigation of CD4 + T cell metabolic fitness, Th1 central nervous system autoimmunity and Th2 asthmatic airway inflammation by therapeutic zinc
Krone, Anna; Fu, Yanpeng; Schreiber, Simon; Kotrba, Johanna; Borde, Loisa; Nötzold, Aileen; Thurm, Christoph; Negele, Jonas; Franz, Tobias; Stegemann-Koniszewski, Sabine; Schreiber, Jens; Garbers, Christoph; Shukla, Aniruddh; Geffers, Robert; Schraven, Burkhart; Reinhold, Dirk; Dudeck, Anne; Reinhold, Annegret; Müller, Andreas Johann; Kahlfuß, Sascha
In: Scientific reports - [London] : Macmillan Publishers Limited, part of Springer Nature, Bd. 12 (2022), Artikel 1943, insges. 14 S.
Untersuchungen zur Wirkung von Adefovir-Dipivoxil und Pitavastatin auf die Funktion humaner T-Zellen
Voss, Linda; Reinhold, Dirk
In: Magdeburg: Universitätsbibliothek, Dissertation Otto-von-Guericke-Universität Magdeburg, Fakultät für Naturwissenschaften 2022, 1 Online-Ressource (IX, 103 Seiten, 4,65 MB) [Literaturverzeichnis: Seite 88-102]
2021
Albumin substitution in decompensated liver cirrhosis - don't forget zinc
Grüngreiff, Kurt; Gottstein, Thomas; Reinhold, Dirk; Blindauer, Claudia A.
In: Nutrients - Basel: MDPI, 2009, Bd. 13 (2021), 11, insges. 19 S.
Zinc aspartate induces IL-16 secretion and apoptosis in human T cells
Reinhold, Dirk; Guttek, Karina; Reddig, Annika; Voss, Linda; Schubert, Claudia; Kahlfuß, Sascha; Grüngreiff, Kurt; Schraven, Burkhart; Reinhold, Annegret
In: Biomedicines - Basel : MDPI, Bd. 9 (2021), Heft 3, Artikel 246, insges. 11 S.
Unique autoantibody prevalence in long-term recovered SARS-CoV-2-infected individuals
Lingel, Holger; Meltendorf, Stefan; Billing, Ulrike; Thurm, Christoph; Vogel, Katrin; Majer, Christiane; Prätsch, Florian; Roggenbuck, Dirk; Heuft, Hans-Gert; Hachenberg, Thomas; Feist, Eugen; Reinhold, Dirk; Brunner-Weinzierl, Monika
In: Journal of autoimmunity - London : Academic Press, Bd. 122 (2021), Artikel 102682, insges. 8 S.
Screening of FDA-approved drug library identifies adefovir dipivoxil as highly potent inhibitor of T cell proliferation
Voss, Linda; Guttek, Karina; Reddig, Annika; Reinhold, Annegret; Voss, Martin; Schraven, Burkhart; Reinhold, Dirk
In: Frontiers in immunology - Lausanne: Frontiers Media, 2010, Bd. 11 (2021), insges. 16 S.
Impact of different JAK inhibitors and methotrexate on lymphocyte proliferation and DNA damage
Reddig, Annika; Voss, Linda; Guttek, Karina; Roggenbuck, Dirk; Feist, Eugen; Reinhold, Dirk
In: Journal of Clinical Medicine - Basel: MDPI, 2012, Bd. 10 (2021), 7, insges. 19 S.
The activity and stability of p56Lck and TCR signaling do not depend on the co-chaperone Cdc37
Kowallik, Sarah; Kritikos, Andreas; Kästle, Matthias; Thurm, Christoph; Schraven, Burkhart; Reinhold, Dirk; Simeoni, Luca
In: International journal of molecular sciences - Basel : Molecular Diversity Preservation International, Bd. 22 (2021), Heft 1, Artikel 126, insges. 12 S.
The differential roles of zinc in immune responses and their potential implications in antiviral immunity against SARS-CoV-2
Reinhold, Dirk; Brocke, Stefan
In: Clinical nutrition - Amsterdam [u.a.]: Elsevier, Bd. 40 (2021), 2, S. 652
Eosinophilic pulmonary vasculitis as a manifestation of the hyperinflammatory phase of COVID-19. Correspondence
Luecke, Eva; Jeron, Andreas; Kröger, Andrea; Bruder, Dunja; Stegemann-Koniszewski, Sabine; Jechorek, Dörthe; Borucki, Katrin; Reinhold, Dirk; Reinhold, Annegret; Föllner, Sebastian; Walles, Thorsten; Hachenberg, Thomas; Schreiber, Jens
In: The journal of allergy and clinical immunology - Amsterdam [u.a.]: Elsevier, Bd. 147 (2021), 1, S. 112-113
Olfactory transmucosal SARS-CoV-2 invasion as a port of central nervous system entry in individuals with COVID-19
Meinhardt, Jenny; Radke, Josefine; Dittmayer, Carsten; Franz, Jonas; Thomas, Carolina; Mothes, Ronja; Laue, Michael; Schneider, Julia; Brünink, Sebastian; Greuel, Selina; Lehmann, Malte; Hassan, Olga; Aschman, Tom; Schumann, Elisa; Chua, Robert Lorenz; Conrad, Christian; Eils, Roland; Stenzel, Werner; Windgassen, Marc; Rößler, Larissa; Goebel, Hans Hilmar; Gelderblom, Hans R.; Martin, Hubert; Nitsche, Andreas; Schulz-Schaeffer, Walter J.; Hakroush, Samy; Winkler, Martin S.; Tampe, Björn; Scheibe, Franziska; Körtvélyessy, Péter; Reinhold, Dirk; Siegmund, Britta; Kühl, Anja Andrea; Elezkurtaj, Sefer; Horst, David; Oesterhelweg, Lars; Tsokos, Michael; Ingold Heppner, Barbara; Stadelmann, Christine; Drosten, Christian; Corman, Victor Max; Radbruch, Helena; Heppner, Frank L.
In: Nature neuroscience - New York, NY : Nature America, Bd. 24 (2021), Heft 2, S. 168-175, insges. 8 S. [Published: 30 November 2020]
Anti-glycoprotein 2 (anti-GP2) IgA and anti-neutrophil cytoplasmic antibodies to serine proteinase 3 (PR3-ANCA) - antibodies to predict severe disease, poor survival and cholangiocarcinoma in primary sclerosing cholangitis
Wunsch, Ewa; Norman, Gary L.; Milkiewicz, Małgorzata; Krawczyk, Marcin; Bentow, Chelsea; Shums, Zakera; Mahler, Michael; Lopens, Steffi; Reinhold, Dirk; Franke, Andre; Schramm, Christoph; Roggenbuck, Dirk; Milkiewicz, Piotr
In: Alimentary pharmacology & therapeutics - Oxford: Blackwell Science, 1987, Bd. 53 (2021), 2, S. 302-313
Pitavastatin is a highly potent inhibitor of T-cell proliferation
Voss, Linda; Guttek, Karina; Reddig, Annika; Reinhold, Annegret; Voss, Martin; Simeoni, Luca; Schraven, Burkhart; Reinhold, Dirk
In: Pharmaceuticals - Basel : MDPI, Bd. 14 (2021), Heft 8, Artikel 727, insges. 19 S.
2020
Autoimmune peripheral neuropathies and contribution of antiganglioside/sulphatide autoantibody testing
Roggenbuck, Dirk; Delmont, Emilien; Reinhold, Dirk; Schierack, Peter; Conrad, Karsten; Boucraut, Joseph
In: Mediterranean journal of rheumatology - Athens: Greek Rheumatology Society, 2015, Bd. 31 (2020), 1, S. 10-18
Gastric cancer in autoimmune gastritis - a case-control study from the German centers of the staR project on gastric cancer research
Weise, Friederike; Vieth, Michael; Reinhold, Dirk; Haybäck, Johannes; Goni, Elisabetta; Lippert, Hans; Ridwelski, Karsten; Lingohr, Philipp; Schildberg, Claus; Vassos, Nikolaos; Kruschewski, Martin; Krasniuk, Iurii; Grimminger, Peter; Waidmann, Oliver; Peitz, Ulrich; Veits, Lothar; Kreuser, Nicole; Lang, Hauke; Bruns, Christiane; Möhler, Markus; Lordick, Florian; Gockel, Ines; Schumacher, Johannes; Malfertheiner, Peter; Venerito, Marino
In: United european gastroenterology journal - Hoboken, NJ : Wiley, Bd. 8 (2020), Heft 2, S. 175-184, insges. 10 S.
Serum and CSF cytokine levels mirror different neuroimmunological mechanisms in patients with LGI1 and Caspr2 encephalitis
Körtvélyessy, Péter; Goihl, Alexander; Guttek, Karina; Schraven, Burkhart; Prüß, Harald; Reinhold, Dirk
In: Cytokine - Oxford [u.a.] : Elsevier - Vol. 135.2020, 155226
Zinc deficiency - an independent risk factor in the pathogenesis of haemorrhagic stroke?
Grüngreiff, Kurt; Gottstein, Thomas; Reinhold, Dirk
In: Nutrients - Basel: MDPI, 2009, Vol. 12.2020, 11, Art.-Nr. 3548, insgesamt 11 Seiten
Ratio and index of neurofilament light chain indicate its origin in GuillainBarré Syndrome
Körtvélyessy, Péter; Kuhle, Jens; Düzel, Emrah; Vielhaber, Stefan; Schmidt, Christian; Heinius, Annika; Leypoldt, Frank; Schraven, Burkhart; Reinhold, Dirk; Leppert, David; Goihl, Alexander
In: Annals of Clinical and Translational Neurology - Chichester [u.a.] : Wiley, Bd. 7 (2020), Heft 11, S. 2213-2220
2019
Characterization of mice with a platelet-specific deletion of the adapter molecule ADAP
Rudolph, Jochen M.; Guttek, Karina; Weitz, Gabriele; Meinke, Clara Antonia; Kliche, Stefanie; Reinhold, Dirk; Schraven, Burkhart; Reinhold, Annegret
In: Molecular and cellular biology - Washington, DC : Soc - Bd. 39.2019, 9, Art.-Nr. e00365-18, insges. 16 S.
Immune cell-type specific ablation of adapter protein ADAP differentially modulates EAE
Rudolph, Jochen M.; Meinke, Clara; Voss, Martin; Guttek, Karina; Kliche, Stefanie; Reinhold, Dirk; Schraven, Burkhart; Reinhold, Annegret
In: Frontiers in immunology - Lausanne: Frontiers Media, 2010, Bd. 10.2019, Art.-Nr. 2343, insges. 13 S.
2018
Combined treatment with zinc aspartate and intravenous immunoglobulins (IVIGs) ameliorates experimental autoimmune encephalomyelitis (EAE)
Straubel, Diana; Thielitz, Anja; Reinhold, Annegret; Grüngreiff, Kurt; Reinhold, Dirk
In: Journal of Immunology Research - New York, NY: Hindawi, 2018, Art.-ID 5982169, insges. 7 S.
Lower serum zinc levels in patients with multiple sclerosis compared to healthy controls
Pawlitzki, Marc; Uebelhör, Julia; Sweeney-Reed, Catherine M.; Stephanik, Heike; Hoffmann, Juliane; Lux, Anke; Reinhold, Dirk
In: Nutrients - Basel: MDPI, 2009, Bd. 10.2018, 8, Art.-Nr. 967, insges. 9 S.
Zinc aspartate suppresses proliferation and Th1/Th2/Th17 cytokine production of pre-activated human T cells in vitro
Guttek, Karina; Wagenbrett, Linda; Reinhold, Annegret; Grüngreiff, Kurt; Reinhold, Dirk
In: Journal of trace elements in medicine and biology - München: Elsevier, Bd. 49.2018, S. 86-90
Antibodies against glycoprotein 2 display diagnostic advantages over ASCA in distinguishing CD from intestinal tuberculosis and intestinal Behçet's disease
Zhang, Shulan; Luo, Jing; Wu, Ziyan; Roggenbuck, Dirk; Schierack, Peter; Reinhold, Dirk; Li, Ji; Zeng, Xiaofeng; Zhang, Fengchun; Qian, Jiaming; Li, Yongzhe
In: Clinical and translational gastroenterology - London: Nature Publ. Group, Bd. 9.2018, Art.-Nr. e133, insges. 11 S.
The potential toxic impact of different gadolinium-based contrast agents combined with 7-T MRI on isolated human lymphocytes
Friebe, Björn; Godenschweger, Frank; Fatahi, Mahsa; Speck, Oliver; Roggenbuck, Dirk; Reinhold, Dirk; Reddig, Annika
In: European radiology experimental - [Cham]: Springer International Publishing, 2017, Bd. 2.2018, Art.-Nr. 40, insges. 9 S.
MRI and genetic damage - an update
Fatahi, Mahsa; Reddig, Annika; Friebe, Björn; Reinhold, Dirk; Speck, Oliver
In: Current radiology reports - New York, NY: Springer, 2013, Bd. 5.2017, Art.-Nr. 20, insges. 7 S.
Generation and validation of murine monoclonal and camelid recombinant single domain antibodies specific for human pancreatic glycoprotein 2
Schlör, Anja; Holzlöhner, Pamela; Listek, Martin; Grieß, Cindy; Butze, Monique; Micheel, Burkhard; Hentschel, Christian; Sowa, Mandy; Roggenbuck, Dirk; Schierack, Peter; Füner, Jonas; Schliebs, Erik; Goihl, Alexander; Reinhold, Dirk; Hanack, Katja
In: New biotechnology - New York, NY [u.a.]: Elsevier, Bd. 45 (2018), S. 60-68
Phosphorylated histone 2AX foci determination in capillary blood mononuclear cells
Sowa, Mandy; Reddig, Annika; Schierack, Peter; Reinhold, Dirk; Roggenbuck, Dirk
In: Journal of laboratory and precision medicine: an open access journal for high-quality research in laboratory medicine : JLPM - Hong Kong: AME Publishing Company, 2016, Bd. 3.2018, Art.-Nr. 45, insges. 6 S.
DNA damage assessment and potential applications in laboratory diagnostics and precision medicine
Reddig, Annika; Rübe, Claudia Elisabeth; Rödiger, Stefan; Schierack, Peter; Reinhold, Dirk; Roggenbuck, Dirk
In: Journal of laboratory and precision medicine - Hong Kong: AME Publishing Company, Bd. 3.2018, Art.-Nr. 31, insges. 15 S.
Comparison of different immunoassays for γH2AX quantification
Reddig, Annika; Roggenbuck, Dirk; Reinhold, Dirk
In: Journal of laboratory and precision medicine: an open access journal for high-quality research in laboratory medicine : JLPM - Hong Kong: AME Publishing Company, Bd. 3.2018, Art.-Nr. 80, insges. 9 S.
Biomarkers of neurodegeneration in autoimmune-mediated encephalitis
Körtvélyessy, Péter; Prüß, Harald; Thurner, Lorenz; Maetzler, Walter; Vittore-Welliong, Deborah; Schultze-Amberger, Jörg; Heinze, Hans-Jochen; Reinhold, Dirk; Leypoldt, Frank; Schreiber, Stephan; Bittner, Daniel Markus
In: Frontiers in neurology - Lausanne : Frontiers Research Foundation - Bd. 9.2018, Art.-Nr. 668, insges. 10 S.
Expression of Zinc transporters ZIP4, ZIP14 and ZnT9 in hepatic carcinogenesis - an immunohistochemical study
Gartmann, Laura; Wex, Thomas; Grüngreiff, Kurt; Reinhold, Dirk; Kalinski, Thomas; Malfertheiner, Peter; Schütte, Kerstin
In: Journal of trace elements in medicine and biology - München: Elsevier, Bd. 49.2018, S. 35-42
CSF macrophage migration inhibitory factor levels did not predict steroid treatment response after optic neuritis in patients with multiple sclerosis
Pawlitzki, Marc; Sweeney-Reed, Catherine M.; Meuth, Sven; Reinhold, Dirk; Neumann, Jens
In: PLOS ONE - San Francisco, California, US: PLOS, 2006, Bd. 13.2018, 11, Art.-Nr. e0207726, insges. 11 S.
Faktoren einer radiologischen Progression der chronisch progredient verlaufenden rheumatoiden Arthritis
Thunert, Isabell; Reinhold, Dirk; Oelzner, Peter
In: Magdeburg: Otto-von-Guericke-Universität Magdeburg, 2018, 72 Blätter, Diagramme
2017
Insights into the mechanism of action of isotretinoin in human sebocytes in vitro
Mirdamadi, Yasaman Sadat; Thielitz, Anja; Wiede, Antje; Goihl, Alexander; Zouboulis, Christos C.; Reinhold, Dirk; Bommhardt, Ursula; Quist, Sven Roy; Gollnick, Harald
In: Experimental dermatology : the official journal of the European Immunodermatology Society - Oxford : Wiley-Blackwell, Bd. 26.2017, 3, P082, S. E35-E36
Insights into the mechanism of action of insulin-like growth factor-1 and insulin in human T cells in vitro
Mirdamadi, Yasaman Sadat; Thielitz, Anja; Goihl, Alexander; Guttek, Karina; Zouboulis, Christos C.; Reinhold, Dirk; Bommhardt, Ursula; Quist, Sven Roy; Gollnick, Harald
In: Experimental dermatology : the official journal of the European Immunodermatology Society - Oxford : Wiley-Blackwell, Bd. 26.2017, 3, P081 (OP06/06), S. E35
Magenkarzinom auf dem Boden einer Autoimmungastritis - eine Fall-Kontroll-Studie aus dem staR (gastric cancer research)-Konsortium
Venerito, Marino; Weise, Friederike; Reinhold, Dirk; Ridwelski, Karsten; Goni, Elisabetta; Lingohr, Philipp; Matthaei, Hanno; Schildberg, Claus; Kruschewski, Martin; Krasniuk, Iurii; Grimminger, Peter; Möhler, Markus; Lippert, Hans; Wolff, Stefanie; Vieth, Michael; Veits, Lothar; Bruns, Christiane; Lordick, Florian; Gockel, Ines; Malfertheiner, Peter; Schumacher, Johannes
In: Zeitschrift für Gastroenterologie: offizielles Organ: Deutsche Gesellschaft für Verdauungs- und Stoffwechselkrankheiten mit Sektion Gastroenterologische Endoskopie : Österreichische Gesellschaft für Gastroenterologie und Hepatologie : Ungarische Gesellschaft für Gastroenterologie und Hepatologie - Stuttgart [u.a.]: Thieme, Bd. 55.2017, 8, insges. 1 S.
Clinical symptom tool raises index of suspicion for eosinophilic oesophagitis in adults and drives earlier biopsy for definitive diagnosis
Arnim, Ulrike; Roehl, Friedrich W.; Miehlke, Stephan; Jechorek, Dörthe; Reinhold, Dirk; Wex, Thomas; Malfertheiner, Peter
In: Gastroenterology - New York, NY : Elsevier - Bd. 152.2017, 5, Suppl. 1, Abs. Tu1094, S. S-859
Impact of in vivo high-field-strength and ultra-high-field-strength MR imaging on DNA double-strand-break formation in human lymphocytes
Reddig, Annika; Fatahi, Mahsa; Roggenbuck, Dirk; Ricke, Jens; Reinhold, Dirk; Speck, Oliver; Friebe, Björn
In: Radiology - Oak Brook, Ill : Soc, Bd. 282 (2017), Heft 3, S. 782-789
Clinical symptom tool that raises the index of suspicion for eosinophilic oesophagitis in adults and drives earlier biopsy for definitive diagnosis
Arnim, Ulrike; Röhl, Friedrich-Wilhelm; Miehlke, Stephan; Jechorek, Dörthe; Reinhold, Dirk; Wex, Thomas; Malfertheiner, Peter
In: Alimentary pharmacology & therapeutics - Oxford : Blackwell Science, Bd. 45 (2017), Heft 3, S. 417-426
Autoantibodies against glycoprotein 2 isoforms in pediatric patients with inflammatory bowel disease
Röber, Nadja; Noß, Lydia; Goihl, Alexander; Reinhold, Dirk; Jahn, Josefine; Laffolie, Jan; Johannes, Wolf; Flemming, Gunter Matthias Christian; Roggenbuck, Dirk; Conrad, Karsten; Laaß, Martin Walter
In: Inflammatory bowel diseases - Oxford : Oxford University Press, Bd. 23 (2017), 9, S. 1624-1636
Letter - multivariate clinical model for eosinophilic oesophagitis is this generalisable to a general population? : Authors reply
Arnim, Ulrike; Röhl, Friedrich-Wilhelm; Miehlke, Stephan; Jechorek, Dörthe; Reinhold, Dirk; Wex, Thomas; Malfertheiner, Peter
In: Alimentary pharmacology & therapeutics - Oxford : Blackwell Science, Bd. 45 (2017), Heft 6, S. 861
Next-generation autoantibody testing by combination of screening and confirmation - the CytoBead® technology
Sowa, Mandy; Hiemann, Rico Frank; Schierack, Peter; Reinhold, Dirk; Conrad, Karsten; Roggenbuck, Dirk
In: Clinical reviews in allergy & immunology - [S.l.]: Springer US, 1983, Bd. 53 (2017), 1, S. 87-104
Serological diagnosis and prognosis of severe acute pancreatitis by analysis of serum glycoprotein 2
Roggenbuck, Dirk; Goihl, Alexander; Hanack, Katja; Holzlöhner, Pamela; Hentschel, Christian; Veiczi, Miklós; Schierack, Peter; Reinhold, Dirk; Schulz, Hans-Ulrich
In: Clinical chemistry and laboratory medicine - Berlin [u.a.]: De Gruyter, 1998, Bd. 55 (2017), 6, S. 854-864
Der neuroimmunologische Boomerang nach Herpes-Simplex-Enzephalitis
Körtvélyessy, Péter; Bartels, Claudius; Galazky, Imke; Ranft, Karin; Sailer, Michael; Schreiber, Stephan; Heinsius, Valentin; Reinhold, Dirk; Vielhaber, Stefan; Heinze, Hans-Jochen; Huchtemann, Tessa
In: Klinische Neurophysiologie: Zeitschrift für Funktionsdiagnostik des Nervensystems ; EEG, EMG, MEP, Motorik, Elektronystagmographie, Kognitive Prozesse, Schlafstörungen - Stuttgart [u.a.]: Thieme, 1980, Bd. 48.2017, 1, S. 44-45
Activated protein C protects from GvHD via PAR2/PAR3 signalling in regulatory T-cells
Ranjan, Satish; Goihl, Alexander; Kohli, Shrey; Gadi, Ihsan; Pierau, Mandy; Shahzad Hussain, Khurrum; Gupta, Dheerendra; Bock, Fabian; Wang, Hongjie; Shaikh, Haroon; Kähne, Thilo; Reinhold, Dirk; Bank, Ute; Zenclussen, Ana Claudia; Niemz, Jana; Schnöder, Tina; Brunner-Weinzierl, Monika; Fischer, Thomas; Kalinski, Thomas; Schraven, Burkhart; Luft, Thomas; Hühn, Jochen; Naumann, Michael; Heidel, Florian; Isermann, Berend
In: Nature Communications - [London] : Nature Publishing Group UK - 8(2017) Artikel-Nummer 311, 16 Seiten
2016
Camelid nanobodies specific to human pancreatic glycoprotein 2
Hanack, Katja; Schlör, Anja; Holzlöhner, Pamela; Listek, Martin; Bauer, Cindy; Butze, Monique; Micheel, Burkhard; Hentschel, Christian; Sowa, Mandy; Roggenbuck, Dirk; Schierack, Peter; Füner, Jonas; Schliebs, Erik; Goihl, Alexander; Reinhold, Dirk
In: The journal of immunology: official journal of the American Association of Immunologists - Rockville, Md.: American Association of Immunologists, 1916, Bd. 196.2016, 1 Suppl.,Abs. 209.8, insges. 1 S.
Characterisation of 242 patients with bullous pemphigoid with and without neurological disorder
Kolesnik, Malgorzata; Ambach, Andreas; Lux, Anke; Reinhold, Dirk; Bonnekoh, Bernd; Gollnick, Harald
In: Experimental dermatology - Oxford : Wiley-Blackwell - Bd. 25.2016, 3, P098, S. E17
In-vivo-Analyse von DNA-Doppelstrangbrüchen in humanen mononukleären Zellen (MNZ) nach klinischen MRT-Untersuchungen
Friebe, Björn; Fatahi, Mahsa; Reddig, Annika; Ricke, Jens; Reinhold, Dirk; Speck, Oliver
In: RöFo: Fortschritte auf dem Gebiet der Röntgenstrahlen und der bildgebenden Verfahren - Stuttgart [u.a.]: Thieme, Bd. 188.2016, S01, Abs. WISS307_1, insges. 1 S.
The mitochondrial phospholipid cardiolipin is involved in the regulation of T-cell proliferation
Mürke, Eik; Stoll, Steffan; Lendeckel, Uwe; Reinhold, Dirk; Schild, Lorenz
In: Biochimica et biophysica acta / Molecular and cell biology of lipids: BBA - Amsterdam: Elsevier, 1998, Bd. 1861.2016, 8 Pt. A, Seite 748-754
Immunomodulation by memantine in therapy of Alzheimer's disease is mediated through inhibition of Kv1.3 channels and T cell responsiveness
Lowinus, Theresa; Bose, Tanima; Busse, Stefan Gregor; Busse, Mandy; Reinhold, Dirk; Schraven, Burkhart; Bommhardt, Ursula H. H.
In: OncoTarget - [S.l.]: Impact Journals LLC, 2010, Bd. 7 (2016), 33, S. 53797-53807
DNA double-strand breaks and micronuclei in human blood lymphocytes after repeated whole body exposures to 7T Magnetic Resonance Imaging
Fatahi, Mahsa; Reddig, Annika; Vijayalaxmi,; Friebe, Björn; Hartig, Roland; Prihoda, Thomas J.; Ricke, Jens; Roggenbuck, Dirk; Reinhold, Dirk; Speck, Oliver
In: NeuroImage - Orlando, Fla: Academic Press, 1993, Bd. 133.2016, S. 288-293
Normal development and function of T cells in proline rich 7 (Prr7) deficient mice
Hrdinka, Matous; Sudan, Kritika; Just, Sissy; Drobek, Ales; Stepanek, Ondrej; Schlüter, Dirk; Reinhold, Dirk; Jordan, Bryen A.; Gintschel, Patricia; Schraven, Burkhart; Kreutz, Michael R.
In: PLOS ONE - San Francisco, California, US: PLOS, 2006, Bd. 11 (2016), 9, Art.-Nr. e0162863, insges. 15 S.
The role of zinc in liver cirrhosis
Grüngreiff, Kurt; Reinhold, Dirk; Wedemeyer, Heiner
In: Annals of hepatology - México : Assoc., Bd. 15 (2016), Heft 1, S. 7-16
Cellular analyses in the monitoring of autoimmune diseases
Sack, Ulrich; Boldt, Andreas; Mallouk, Nora; Gruber, Rudolf; Krenn, Veit; Berger-Depincé, Anne-Emmanuelle; Conrad, Karsten; Tárnok, Attila; Lambert, Claude; Reinhold, Dirk; Fricke, Stephan
In: Autoimmunity reviews - Amsterdam [u.a.]: Elsevier Science, 2002, Bd. 15.2016, 9, S. 883-889
Serologic anti-GP2 antibodies are associated with genetic polymorphisms, fibrostenosis, and need for surgical resection in Crohn's disease
Degenhardt, Frauke; Dirmeier, Andrea; Lopez, Rocio; Lang, Sylvia; Kunst, Claudia; Roggenbuck, Dirk; Reinhold, Dirk; Szymczak, Silke; Rogler, Gerhard; Klebl, Frank; Franke, Andre; Rieder, Florian
In: Inflammatory bowel diseases - Oxford: Oxford University Press, 1995, Bd. 22.2016, 11, S. 2648-2657
Autoimmunity in Crohn's disease - a putative stratification factor of the clinical phenotype
Roggenbuck, Dirk; Reinhold, Dirk; Baumgart, Daniel C.; Schierack, Peter; Conrad, Karsten; Laass, Martin W.
In: Advances in clinical chemistry - New York, NY [u.a.]: Elsevier, 2001, Bd. 77.2016, S. 77-101
Increased cerebral Tff1 expression in two murine models of neuroinflammation
Znalesniak, Eva B.; Fu, Ting; Guttek, Karina; Händel, Ulrike; Reinhold, Dirk; Hoffmann, Werner
In: Cellular physiology and biochemistry - Düsseldorf: Cell Physiol Biochem Press GmbH & Co KG, 1991, Bd. 39.2016, 6, S. 2287-2296
Simultaneous detection of celiac disease-specific IgA antibodies and total IgA
Großmann, Kai; Röber, Nadja; Hiemann, Rico Frank; Rödiger, Stefan; Schierack, Peter; Reinhold, Dirk; Laass, Martin W.; Conrad, Karsten; Roggenbuck, Dirk
In: Autoimmunity highlights - Mailand: Springer Milan, 2010, Bd. 7.2016, 1, Art.-Nr. 2, insges. 10 S.
Oxyntic gastric atrophy in Helicobacter pylori gastritis is distinct from autoimmune gastritis
Venerito, Marino; Varbanova, Mariya; Röhl, Friedrich-Wilhelm; Reinhold, Dirk; Frauenschläger, Katrin; Jechorek, Dörthe; Weigt, Jochen; Link, Alexander; Malfertheiner, Peter
In: Journal of clinical pathology - London : BMJ Publ. Group, Bd. 69 (2016), Heft 8, S. 677-685
2015
Serologische Diagnose der fortgeschrittenen oxyntischen Magenatrophie bei Patienten mit Helicobacter pylori Gastritis und Autoimmungastritis
Venerito, Marino; Varbanova, Mariya; Röhl, Friedrich-Wilhelm; Link, Alexander; Reinhold, Dirk; Frauenschläger, Katrin; Malfertheiner, Peter
In: Zeitschrift für Gastroenterologie : offizielles Organ: Deutsche Gesellschaft für Verdauungs- und Stoffwechselkrankheiten mit Sektion Gastroenterologische Endoskopie ; Österreichische Gesellschaft für Gastroenterologie und Hepatologie ; Ungarische Gesellschaft für Gastroenterologie und Hepatologie. - Stuttgart [u.a.] : Thieme; Bd. 53.2015, 8, KG019, insges. 1 S.
Oxyntic gastric atrophy in autoimmune gastritis compared to Helicobacter pylori gastritis
Venerito, Marino; Varbanova, Mariya; Röhl, Friedrich-Wilhelm; Reinhold, Dirk; Frauenschläger, Katrin; Weigt, Jochen; Link, Alexander; Malfertheiner, Peter
In: Helicobacter - Oxford [u.a.] : Wiley-Blackwell - Bd. 20.2015, Suppl. 1, Abs. P01.17, S. 90
Effects of isotretinoin on FoxO1 transcriptional regulation and molecular functions of SZ95 sebocytes
Mirdamadi, Yasaman Sadat; Thielitz, Anja; Wiede, Antje; Goihl, Alexander; Zouboulis, Christos C.; Reinhold, Dirk; Bommhardt, Ursula; Quist, Sven Roy; Gollnick, Harald
In: Experimental dermatology: the official journal of the European Immunodermatology Society - Oxford: Wiley-Blackwell, Bd. 24.2015, 3, P068, S. E12
Assessment of modulated cytostatic drug resistance by automated [gamma]H2AX analysis
Reddig, Annika; Lorenz, Sebastian; Hiemann, Rico Frank; Guttek, Karina; Hartig, Roland; Heiserich, Lisa; Eberle, Caroline; Peters, Vanessa; Schierack, Peter; Sack, Ulrich; Roggenbuck, Dirk; Reinhold, Dirk
In: Cytometry / A - Hoboken, NJ: Wiley-Liss, 2003, Bd. 87.2015, 8, S. 724-732
Autoreactivity to isoforms of glycoprotein 2 in inflammatory bowel disease. Letter to the editor
Roggenbuck, Dirk; Röber, Nadja; Bogdanos, Dimitrios P.; Goihl, Alexander; Reinhold, Dirk; Conrad, Karsten; Laaß, Martin Walter
In: Clinica chimica acta: international journal of clinical chemistry and applied molecular biology - Amsterdam [u.a.]: Elsevier Science, Bd. 442 (2015), S. 82-83
Evidence of Crohn's disease-related anti-glycoprotein 2 antibodies in patients with celiac disease
Roggenbuck, Dirk; Vermeire, Severine; Hoffman, Ilse; Reinhold, Dirk; Schierack, Peter; Goihl, Alexander; Arnim, Ulrike; Hertogh, Gert; Polymeros, Dimitrios; Bogdanos, Dimitrios P.; Bossuyt, Xavier
In: Clinical chemistry and laboratory medicine - Berlin [u.a.] : De Gruyter, Bd. 53 (2015), Heft 9, S. 1349-1357
Der Einfluss des Spurenelements Zink auf das Immunsystem
Schubert, Claudia; Guttek, Karina; Reinhold, Annegret; Grüngreiff, Kurt; Reinhold, Dirk
In: Laboratoriumsmedizin - Berlin [u.a.]: de Gruyter, 1977, Bd. 39.2015, 3, S. 135-144
Analysis of DNA double-strand breaks and cytotoxicity after 7 Tesla magnetic resonance imaging of isolated human lymphocytes
Reddig, Annika; Fatahi, Mahsa; Friebe, Björn; Guttek, Karina; Hartig, Roland; Godenschweger, Frank; Roggenbuck, Dirk; Ricke, Jens; Reinhold, Dirk; Speck, Oliver
In: PLOS ONE - San Francisco, California, US : PLOS - Vol. 10.2015, 7, Art. e0132702, insgesamt 14 S.
MiR-20a inhibits TCR-mediated signaling and cytokine production in human naïve CD4+ T cells
Reddycherla, Amarendra Varma; Meinert, Ines; Reinhold, Annegret; Reinhold, Dirk; Schraven, Burkhart; Simeoni, Luca
In: PLOS ONE - San Francisco, California, US: PLOS, Bd. 10.2015, 4, Art. e0125311, insges. 17 S.
Second generation analysis of antinuclear antibody (ANA) by combination of screening and confirmatory testing
Scholz, Juliane; Großmann, Kai; Knütter, Ilka; Hiemann, Rico Frank; Sowa, Mandy; Röber, Nadja; Rödiger, Stefan; Schierack, Peter; Reinhold, Dirk; Bogdanos, Dimitrios P.; Meroni, Pier Luigi; Radice, Antonella; Conrad, Karsten; Roggenbuck, Dirk
In: Clinical chemistry and laboratory medicine - Berlin [u.a.]: De Gruyter, Bd. 53 (2015), 12, S. 1991-2002
Species-specific and pathotype-specific binding of bacteria to zymogen granule membrane glycoprotein 2 (GP2). Postscript
Schierack, Peter; Rödiger, Stefan; Kolenda, Rafal; Hiemann, Rico Frank; Berger, Enrico; Grzymajło, Krzysztof; Swidsinski, Alexander; Juretzek, Thomas; Meissner, Dirk; Mydlak, Karsten; Reinhold, Dirk; Nolan, Lisa K.; Roggenbuck, Dirk
In: Gut - London: BMJ Publishing Group, 1960, Bd. 64.2015, 3, S. 517-519
Autoimmune gastritis in autoimmune thyroid disease
Venerito, Marino; Radünz, Marcus; Reschke, Kirsten; Reinhold, Dirk; Frauenschläger, Katrin; Jechorek, Dörthe; DiMario, Francesco; Malfertheiner, Peter
In: Alimentary pharmacology & therapeutics - Oxford : Blackwell Science, Bd. 41 (2015), Heft 7, S. 686-693
Insulin and insulin-like growth factor-1 can modulate the phosphoinositide-3-kinase/Akt/FoxO1 pathway in SZ95 sebocytes in vitro
Mirdamadi, Yasaman Sadat; Thielitz, Anja; Wiede, Antje; Goihl, Alexander; Papakonstantinou, Eleni; Hartig, Roland; Zouboulis, Christos C.; Reinhold, Dirk; Simeoni, Luca; Bommhardt, Ursula; Quist, Sven Roy; Gollnick, Harald
In: Molecular and cellular endocrinology - Amsterdam [u.a.]: Elsevier Science, Bd. 415 (2015), S. 32-44
The adhesion- and degranulation-promoting adaptor protein and its role in the modulation of experimental autoimmune encephalomyelitis
Engelmann, Swen; Togni, Mauro; Kliche, Stefanie; Reinhold, Dirk; Schraven, Burkhart; Reinhold, Annegret
In: Critical reviews in immunology - Boca Raton, Fla. : CRC Press, Bd. 35 (2015), Heft 1, S. 1-14
Interleukin 18 als Diagnose- und Verlaufsparameter beim Morbus Still
Kudela, Holger; Reinhold, Dirk
In: Magdeburg, Univ., Med. Fak., Diss., 2015, 91 Bl
Regulation der Interleukin-2-Sekretion in primären humanen T-Lymphozyten durch Cannabinoide
Wachter, Doreen; Reinhold, Dirk
In: Magdeburg Univ., Med. Fak., Diss., 2015, VIII, 77 Bl, Ill., graph. Darst.
2014
Autoantibodies to glycoprotein 2 are associated with the clinical phenotype in Crohn's disease
Roggenbuck, Dirk; Bogdanos, Dimitrios P.; Reinhold, Dirk; Arnim, Ulrike; Malfertheiner, Peter; Forbes, Alastair; Conrad, Karsten; Laaß, Martin Walter
In: Zeitschrift für Gastroenterologie - Stuttgart [u.a.] : Thieme - Bd. 52.2014, Nr. 8, FV13, insges. 1 S.
Constitutive expression of murine c-FLIPR causes autoimmunity in aged mice
Ewald, Frida; Annemann, Michaela; Pils, Marina C.; Plaza-Sirvent, Carlos; Neff, Frauke; Erck, Christian; Reinhold, Dirk; Schmitz, Ingo
In: Cell death & disease - London [u.a.]: Nature Publishing Group, Bd. 5.2014, Art.-Nr. e1168, insges. 12 S.
Expression analysis of zinc transporters in resting and stimulated human peripheral blood mononuclear cells
Wex, Thomas; Grüngreiff, Kurt; Schütte, Kerstin; Stengritt, Maren; Reinhold, Dirk
In: Biomedical reports: an international journal devoted to biomedical research - Athens: Spandidos Publ., Bd. 2 (2014), 2, S. 217-222
DPP4-directed therapeutic strategies for MERS-CoV. Correspondence
Reinhold, Dirk; Brocke, Stefan
In: The lancet
Digital immunofluorescence enables automated detection of antinuclear antibody endpoint titers avoiding serial dilution
Roggenbuck, Dirk; Hiemann, Rico Frank; Schierack, Peter; Reinhold, Dirk; Conrad, Karsten
In: Clinical chemistry and laboratory medicine - Berlin [u.a.]: De Gruyter, Bd. 52.2014, 2, S. e9-e11
Oral zinc aspartate treats experimental autoimmune encephalomyelitis
Schubert, Claudia; Guttek, Karina; Grüngreiff, Kurt; Thielitz, Anja; Bühling, Frank; Reinhold, Annegret; Brocke, Stefan; Reinhold, Dirk
In: BioMetals - Dordrecht [u.a.]: Springer Science + Business Media B.V, Bd. 27 (2014), 6, S. 1249-1262
Treatment of severe autoimmune blistering skin diseases with combination of protein A immunoadsorption and rituximab - a protocol without initial high dose or pulse steroid medication
Kolesnik, Malgorzata; Becker, Elke; Reinhold, Dirk; Ambach, Andreas; Heim, Marcell U.; Gollnick, Harald; Bonnekoh, Bernd
In: Journal of the European Academy of Dermatology and Venereology - Oxford [u.a.]: Wiley-Blackwell, Bd. 28 (2014), 6, S. 771-780
Crohnʾs disease specific pancreatic antibodies - clinical and pathophysiological challenges
Roggenbuck, Dirk; Reinhold, Dirk; Schierack, Peter; Bogdanos, Dimitrios P.; Conrad, Karsten; Laaß, Martin Walter
In: Clinical chemistry and laboratory medicine - Berlin [u.a.]: De Gruyter, Bd. 52 (2014), 4, S. 483-494
Selective targeting of transforming growth factor-beta1 into TCR/CD28 signalling plasma membrane domains silences T cell activation
Harder, Thomas; Guttek, Karina; Philipsen, Lars; Simeoni, Luca; Schraven, Burkhart; Reinhold, Dirk
In: Cell communication and signaling - London: Biomed Central, 2003, Bd. 12.2014, Art.-Nr. 74, insges. 8 S.
Simultaneous automated screening and confirmatory testing for vasculitis-specific ANCA
Sowa, Mandy; Großmann, Kai; Knütter, Ilka; Hiemann, Rico Frank; Röber, Nadja; Anderer, Ursula; Csernok, Elena; Bogdanos, Dimitrios P.; Borghi, Maria Orietta; Meroni, Pier Luigi; Schierack, Peter; Reinhold, Dirk; Conrad, Karsten; Roggenbuck, Dirk
In: PLOS ONE - San Francisco, California, US: PLOS, Bd. 9.2014, 9, Art.-Nr. e107743, insges. 11 S.
2013
Training intervention improves memory in mild cognitive impairment and healthy controls, but plasma BDNF acts differentially
Bittner, Daniel Markus; Bittner, Verena; Hausmann, Janet; Reinhold, Dirk; Wesenberg, Judith; Westphal, Sabine; Heinze, Hans-Jochen; Schott, Björn H.; Kaufmann, Jörn; Müller, N. J.
In: Journal of psychophysiology - Göttingen : Hogrefe & Huber - Bd. 27.2013, Suppl. 1, S. 49
Aklides - a highly versatile imaging platform for detection of ANCA
Knütter, Ilka; Großmann, Kai; Hiemann, Rico Frank; Reinhold, Dirk; Csernok, Elena; Roggenbuck, Dirk
In: La presse médicale & Quarterly medical review - Issy-les-Moulineaux : Elsevier Masson, Bd. 42 (2013), Heft 4, S. 686
DP IV/CD26 effector peptides
Ansorge, Siegfried; Reinhold, Dirk
In: Handbook of biologically active peptides , 2. ed. - Amsterdam : Elsevier Academic Press ; Kastin, Abba J. . - 2013, S. 664-670
Fully automated analysis of chemically induced [gamma]H2AX foci in human peripheral blood mononuclear cells by indirect immunofluorescence
Willitzki, Annika; Lorenz, Sebastian; Hiemann, Rico Frank; Guttek, Karina; Goihl, Alexander; Hartig, Roland; Conrad, Karsten; Feist, Eugen; Sack, Ulrich; Schierack, Peter; Heiserich, Lisa; Eberle, Caroline; Peters, Vanessa; Roggenbuck, Dirk; Reinhold, Dirk
In: Cytometry / A - Hoboken, NJ: Wiley-Liss, Bd. 83 (2013), 11, S. 1017-1026
Humanes Leukozytenantigensystem in der Augenheilkunde
Lapp, Thabo; Reinhold, Dirk; Böhringer, Daniel; Reinhard, Thomas
In: Der Ophthalmologe - Berlin: Springer, Bd. 110 (2013), 9, S. 849-861
Glycoprotein 2 antibodies in Crohn's disease
Roggenbuck, Dirk; Reinhold, Dirk; Werner, Lael; Schierack, Peter; Bogdanos, Dimitrios P.; Conrad, Karsten
In: Advances in clinical chemistry - New York, NY [u.a.]: Elsevier, Bd. 60 (2013), S. 187-208
Glycoprotein 2 antibodies in inflammatory bowel disease - No association with disease phenotype?. Letters to the editor
Roggenbuck, Dirk; Humbel, René-Louis; Reinhold, Dirk; Bogdanos, Dimitrios P.; Conrad, Karsten; Laaß, Martin Walter
In: Journal of pediatric gastroenterology and nutrition - Philadelphia, Pa.: Lippincott Williams & Wilkins, Bd. 56 (2013), 1, S. e5
Standardization of automated interpretation of immunofluorescence tests. Letter to the editor
Roggenbuck, Dirk; Hiemann, Rico Frank; Bogdanos, Dimitrios; Reinhold, Dirk; Conrad, Karsten
In: Clinica chimica acta: CCA ; international journal of clinical chemistry and medical biochemistry / ed. in chief S. C. Frazer - Amsterdam: Elsevier, Bd. 421 (2013), S. 168-169
T cell-independent modulation of experimental autoimmune encephalomyelitis in ADAP-deficient mice
Engelmann, Swen; Togni, Mauro; Reinhold, Dirk; Thielitz, Anja; Reichardt, Peter; Kliche, Stefanie; Schraven, Burkhart; Reinhold, Annegret
In: The journal of immunology - Bethesda, Md: Soc, Bd. 191 (2013), 10, S. 4950-4959
Cooperative immunoregulatory function of the transmembrane adaptor proteins SIT and LAX
Arndt, Börge; Kalinski, Thomas; Reinhold, Dirk; Thielitz, Anja; Roessner, Albert; Schraven, Burkhart; Simeoni, Luca
In: Journal of leukocyte biology - Bethesda, Md. : FASEB, Bd. 93 (2013), Heft 3, S. 353-362
Stimulated human peripheral T cells produce high amounts of IL-35 protein in a proliferation-dependent manner
Guttek, Karina; Reinhold, Dirk
In: Cytokine - Oxford [u.a.]: Elsevier, Bd. 64 (2013), 1, S. 46-50
2012
Pancreatic-specific autoantibodies to glycoprotein 2 mirror disease location and behaviour in younger patients with Crohn's disease
Bogdanos, Dimitrios P.; Roggenbuck, Dirk; Reinhold, Dirk; Wex, Thomas; Pavlidis, Polychronis; Arnim, Ulrike; Malfertheiner, Peter; Forbes, Alastair; Conrad, Karsten; Laaß, Martin Walter
In: BMC gastroenterology - London : BioMed Central - Bd. 12.2012, Art.-Nr. 102, insges. 9 S.
Dipeptidyl peptidase IV, aminopeptidase N and DPIV/APN-like proteases in cerebral ischemia
Röhnert, Peter; Schmidt, Werner; Emmerlich, Patrick; Goihl, Alexander; Wrenger, Sabine; Bank, Ute; Nordhoff, Karsten; Täger, Michael; Ansorge, Siegfried; Reinhold, Dirk; Striggow, Frank
In: Journal of neuroinflammation - London : BioMed Central - Bd. 9.2012, Artikel-Nr.44, insges. 15 S.
Autoantibody diagnostics in clinical practice
Conrad, Karsten; Roggenbuck, Dirk; Reinhold, Dirk; Sack, Ulrich
In: Autoimmunity reviews - Amsterdam [u.a.] : Elsevier, Bd. 11 (2012), Heft 3, S. 207-211
Zinc aspartate suppresses T cell activation in vitro and relapsing experimental autoimmune encephalomyelitis in SJL/J mice
Stoye, Diana; Schubert, Claudia; Goihl, Alexander; Guttek, Karina; Reinhold, Annegret; Brocke, Stefan; Grüngreiff, Kurt; Reinhold, Dirk
In: BioMetals - Oxford : Rapid Communications, Bd. 25 (2012), Heft 3, S. 529-539
Progressive lipo-lymphedema associated with increased activity of dermal fibroblasts in monoclonal gammopathy of undetermined significance: is there a causal relationship?
Thielitz, Anja; Bellutti, Michael; Bonnekoh, Bernd; Franke, Ingolf; Wiede, Antje; Lotzing, Marita; Reinhold, Dirk; Gollnick, Harald
In: Lymphology: official organ of the International Society of Lymphology / chief ed. J. Bircher - Tucson, Ariz.: International Society of Lymphology: official organ of the International Society of Lymphology / chief ed. J. Bircher, Bd. 45 (2012), 3, S. 124-129
New platform technology for comprehensive serological diagnostics of autoimmune diseases
Willitzki, Annika; Hiemann, Rico Frank; Peters, Vanessa; Sack, Ulrich; Schierack, Peter; Rödiger, Stefan; Anderer, Ursula; Conrad, Karsten; Bogdanos, Dimitrios P.; Reinhold, Dirk; Roggenbuck, Dirk
In: Clinical & developmental immunology - New York, NY: Hindawi, 2012, Art.ID 284740, insges. 18 S.
The Authors' reply. Letter
Roggenbuck, Dirk; Reinhold, Dirk; Wex, Thomas; Arnim, Ulrike; Malfertheiner, Peter; Sturm, Andreas; Werner, Lael; Bogdanos, Dimitrios P.; Laaß, Martin Walter; Conrad, Karsten
In: Gut - London : BMJ Publishing Group, Bd. 61 (2012), Heft 1, S. 164-165
Asialoglycoprotein receptor (ASGPR): a peculiar target of liver-specific autoimmunity
Roggenbuck, Dirk; Mytilinaiou, Maria G.; Lapin, Sergey V.; Reinhold, Dirk; Conrad, Karsten
In: Autoimmunity highlights - Mailand: Springer Milan, Bd. 3 (2012), 3, S. 119-125
Methodologic issues in the measurement of interleukin-16 in clinical blood samples using immunoassays
Goihl, Alexander; Rolle, Anna-Maria; Kähne, Thilo; Reinhold, Annegret; Wrenger, Sabine; Reinhold, Dirk
In: Cytokine - Oxford [u.a.] : Elsevier, Bd. 58 (2012), Heft 1, S. 1-5
Automated interpretation of ANCA patterns - a new approach in the serology of ANCA-associated vasculitis
Knütter, Ilka; Hiemann, Rico Frank; Brumma, Therese; Büttner, Thomas; Großmann, Kai; Cusini, Marco; Pregnolato, Francesca; Borghi, Maria Orietta; Anderer, Ursula; Conrad, Karsten; Reinhold, Dirk; Roggenbuck, Dirk; Csernok, Elena
In: Arthritis Research & Therapy - London: BioMed Central, Bd. 14.2012, 6, Art.-Nr. R271, insges. 10 S.
Pro-inflammatory effector Th cells transmigrate through anti-inflammatory environments into the murine fetus
Wienecke, Janine; Hebel, Katrin; Hegel, Kolja J.; Pierau, Mandy; Brune, Thomas; Reinhold, Dirk; Pethe, Annette; Brunner-Weinzierl, Monika
In: Placenta - Amsterdam [u.a.] : Elsevier, Bd. 33 (2012), Heft 1, S. 39-46
The adapter protein ADAP is required for selected dendritic cell functions
Togni, Mauro; Engelmann, Swen; Reinhold, Dirk; Schraven, Burkhart; Reinhold, Annegret
In: Cell communication and signaling - London : Biomed Central - Bd. 10.2012, Art. 14, insges. 10 S.
Altes Immunsystem - neue Erkenntnisse? - Bedeutung mononukleärer Zellen bei der allogenen Hornhauttransplantatabstoßung
Lapp, Thabo; Reinhold, Dirk; Maier, Philip; Reinhard, Thomas
In: Der Ophthalmologe - Berlin : Springer Medizin, Bd. 109 (2012), Heft 9, S. 869-878
Ektopeptidasen - Von der Forschung in die Klinik - Ectopeptidases - from research to clinical application
Thielitz, Anja; Reinhold, Dirk; Täger, Michael; Bank, Ute; Ansorge, Siegfried; Gollnick, Harald
In: Aktuelle Dermatologie - Stuttgart : Thieme, Bd. 38 (2012), Heft 3, S. 85-87
2011
Autoantibodies to GP2, the major zymogen granule membrane glycoprotein, are new markers in Crohn's disease
Roggenbuck, Dirk; Reinhold, Dirk; Wex, Thomas; Goihl, Alexander; Arnim, Ulrike; Malfertheiner, Peter; Büttner, Thomas; Porstmann, Tomas; Porstmann, Silvia; Liedvogel, Bodo; Bogdanos, Dimitrios P.; Laaß, Martin Walter; Conrad, Karsten
In: Clinica chimica acta - Amsterdam : Elsevier, Bd. 412 (2011), Heft 9/10, S. 718-724
Diagnostic value, clinical utility and pathogenic significance of reactivity to the molecular targets of Crohn's disease specific-pancreatic autoantibodies
Bogdanos, Dimitrios P.; Rigopoulou, Eirini I.; Smyk, Daniel S.; Roggenbuck, Dirk; Reinhold, Dirk; Forbes, Alastair; Laaß, Martin Walter; Conrad, Karsten
In: Autoimmunity reviews - Amsterdam [u.a.] : Elsevier, Bd. 11 (2011), Heft 2, S. 143-148
Standardized detection of anti-ds DNA antibodies by indirect immunofluorescence - a new age for confirmatory tests in SLE diagnostics. Letter to the editor
Roggenbuck, Dirk; Reinhold, Dirk; Hiemann, Rico Frank; Anderer, Ursula; Conrad, Karsten
In: Clinica chimica acta - Amsterdam : Elsevier, Bd. 412 (2011), Heft 21/22, S. 2011-2012
Novel aspects of cellular action of dipeptidyl peptidase IV/CD26
Ansorge, Siegfried; Nordhoff, Karsten; Bank, Ute; Heimburg, Anke; Julius, Heiko; Breyer, Doreen; Thielitz, Anja; Reinhold, Dirk; Täger, Michael
In: Biological chemistry - Berlin [u.a.] : de Gruyter, Bd. 392 (2011), Heft 3, S. 153-168
Divergent actions by inhibitors of DP IV and APN family enzymes on CD4+ Teff cell motility and functions
Biton, Aliza; Ansorge, Siegfried; Bank, Ute; Täger, Michael; Reinhold, Dirk; Brocke, Stefan
In: Immunobiology - Amsterdam : Elsevier, Bd. 216 (2011), Heft 12, S. 1295-1301
PETIR-001, a dual inhibitor of dipeptidyl peptidase IV (DP IV) and aminopeptidase N (APN), ameliorates experimental autoimmune encephalomyelitis in SJL/J mice
Reinhold, Dirk; Bank, Ute; Entz, Dominik; Goihl, Alexander; Stoye, Diana; Wrenger, Sabine; Brocke, Stefan; Thielitz, Anja; Stefin, Sofia; Nordhoff, Karsten; Heimburg, Anke; Täger, Michael; Ansorge, Siegfried
In: Biological chemistry - Berlin [u.a.] : de Gruyter, Bd. 392 (2011), Heft 3, S. 233-237
The transmembrane adaptor protein SIT inhibits TCR-mediated signaling
Arndt, Börge; Krieger, Tina; Kalinski, Thomas; Thielitz, Anja; Reinhold, Dirk; Roessner, Albert; Schraven, Burkhart; Simeoni, Luca
In: PLOS ONE - San Francisco, California, US : PLOS - Bd. 6.2011, 9, Art.-Nr. e23761 insges. 7 S.
The zymogen granule protein 2 (GP2) binds to scavenger receptor expressed on endothelial cells I (SREC-I)
Hölzl, Markus A.; Hofer, Johannes; Kovarik, Johannes J.; Roggenbuck, Dirk; Reinhold, Dirk; Goihl, Alexander; Gärtner, Miriam; Steinberger, Peter; Zlabinger, Gerhard J.
In: Cellular immunology - San Diego, Calif. : Elsevier, Bd. 267 (2011), Heft 2, S. 88-93
Outside or inside: role of the subcellular localization of DP4-like enzymes for substrate conversion and inhibitor effects
Bank, Ute; Heimburg, Anke; Wohlfarth, Astrid; Koch, Gudrun; Nordhoff, Karsten; Julius, Heiko; Helmuth, Martin; Breyer, Doreen; Reinhold, Dirk; Täger, Michael; Ansorge, Siegfried
In: Biological chemistry - Berlin [u.a.] : de Gruyter, Bd. 392 (2011), Heft 3, S. 169-187
2010
Profiling of rheumatoid arthritis associated autoantibodies
Conrad, Karsten; Roggenbuck, Dirk; Reinhold, Dirk; Dörner, Thomas
In: Autoimmunity reviews - Amsterdam [u.a.] : Elsevier, Bd. 9 (2010), Heft 6, S. 431-435
High sensitive detection of double-stranded DNA antibodies by a modified Crithidia luciliae immunofluorescence test may improve diagnosis of systemic lupus erythematosus
Roggenbuck, Dirk; Conrad, Karsten; Reinhold, Dirk
In: Clinica chimica acta - Amsterdam : Elsevier, Bd. 411 (2010), Heft 21/22, S. 1837-1838
2009
Ektopeptidaseinhibitoren als Instrumente eines neuen Therapiekonzeptes zur Behandlung der Akne vulgaris
Thielitz, Anja; Reinhold, Dirk; Täger, Michael; Ansorge, Siegfried; Gollnick, Harald
In: Spitzenforschung in der Dermatologie und Allergologie: Innovationen und Auszeichnungen 2009 / DGAKI; DDG. [Red.-Leitung und Koordinierung der Beitr.: Angela Verse-Herrmann]: Innovationen und Auszeichnungen 2009 - Lampertheim: Alpha-Informationsges., 2009 . - 2009, insges. 6 S.
Plasma concentrations of zinc, copper, interleukin-6 and interferon-[gamma], and plasma dipeptidyl peptidase IV activity in chronic hepatitis C
Grüngreiff, Kurt; Hebell, Thomas; Gutensohn, Kai; Reinhold, Annegret; Reinhold, Dirk
In: Molecular medicine reports . - Athens : Spandidos Publ., Bd. 2.2009, 1, S. 63-68; Abstract
Identification of GP2, the major zymogen granule membrane glycoprotein, as the autoantigen of pancreatic antibodies in Crohn's disease
Roggenbuck, Dirk; Hausdorf, Gert; Martinez-Gamboa, Lorena; Reinhold, Dirk; Büttner, Thomas; Jungblut, Peter R.; Porstmann, Tomas; Laaß, Martin Walter; Henker, Jobst; Büning, Carsten; Feist, Eugen; Conrad, Karsten
In: Gut: the journal of the British Society of Gastroenterology ; an international journal of gastroenterology and hepatology / ed. Sheila Sherlock: the journal of the British Society of Gastroenterology ; an international journal of gastroenterology and hepatology - London: BMJ Publishing Group, 1960, Bd. 58.2009, 12, S. 1620-1628
High-sensitive detection of autoantibodies against proteinase-3 by a novel third-generation enzyme-linked immunosorbent assay
Roggenbuck, Dirk; Büttner, Thomas; Hoffmann, Lars; Schmechta, Helmuth; Reinhold, Dirk; Conrad, Karsten
In: Annals of the New York Academy of Sciences - Hoboken, NJ : Wiley Subscription Services, Bd. 1173 (2009), S. 41-46
Increased blood plasma concentrations of TGF-[beta]1 and TGF-[beta]2 after treatment with intravenous immunoglobulins in childhood autoimmune diseases
Rißmann, Anke; Pieper, Stefanie; Adams, Ines; Brune, Thomas; Wiemann, Dagobert; Reinhold, Dirk
In: Pediatric allergy and immunology - Oxford : Wiley-Blackwell, Bd. 20 (2009), Heft 3, S. 261-265
Role of dipeptidyl peptidase IV (DP IV)-like enzymes in T lymphocyte activation: investigations in DP IV/CD26-knockout mice
Reinhold, Dirk; Goihl, Alexander; Wrenger, Sabine; Reinhold, Annegret; Kühlmann, Ulrike C.; Faust, Jürgen; Neubert, Klaus; Thielitz, Anja; Brocke, Stefan; Täger, Michael; Ansorge, Siegfried; Bank, Ute
In: Clinical chemistry and laboratory medicine - Berlin : ˜deœ Gruyter, Bd. 47 (2009), Heft 3, S. 268-274
Modulation of cytokine production and silica-induced lung fibrosis by inhibitors of aminopeptidase N and of dipeptidyl peptidase-IV-related proteases
Kühlmann, Ulrike C.; Chwieralski, Caroline Elisabeth; Brule, Sybille; Röcken, Christoph; Reinhold, Dirk; Welte, Tobias; Bühling, Frank
In: Life sciences - Amsterdam [u.a.] : Elsevier, Bd. 84 (2009), Heft 1/2, S. 1-11
Radiation-induced matrix production of lung fibroblasts is regulated by interleukin-8
Kühlmann, Ulrike C.; Chwieralski, Caroline Elisabeth; Reinhold, Dirk; Welte, Tobias; Bühling, Frank
In: International journal of radiation biology - Abingdon : Informa Healthcare, Bd. 85 (2009), Heft 2, S. 138-143
Expression of SKAP-HOM in DCs is required for an optimal immune response in vivo
Reinhold, Annegret; Reimann, Sibylle; Reinhold, Dirk; Schraven, Burkhart; Togni, Mauro
In: Journal of leukocyte biology - Bethesda, Md. : FASEB, Bd. 86 (2009), Heft 1, S. 61-71
Recent insights into the role of dipeptidyl aminopeptidase IV (DPIV) and aminopeptidase N (APN) families in immune functions
Ansorge, Siegfried; Bank, Ute; Heimburg, Anke; Helmuth, Martin; Koch, Gudrun; Tadje, Janine; Lendeckel, Uwe; Wolke, Carmen; Neubert, Klaus; Faust, Jürgen; Fuchs, Petra; Reinhold, Dirk; Thielitz, Anja; Täger, Michael
In: Clinical chemistry and laboratory medicine - Berlin : ˜deœ Gruyter, Bd. 47 (2009), Heft 3, S. 253-261
High sensitive detection of double-stranded DNA autoantibodies by a modified Crithidia luciliae immunofluorescence test
Conrad, Karsten; Ittenson, Annelore; Reinhold, Dirk; Fischer, Richard; Roggenbuck, Dirk; Büttner, Thomas; Bosselmann, Hans-Peter; Steinbach, Jörg; Schößler, Werner
In: Annals of the New York Academy of Sciences - Hoboken, NJ : Wiley Subscription Services, Bd. 1173 (2009), S. 180-185
2008
Non-substrate peptides influencing dipeptidyl peptidase IV/CD26 activity and immune cell function
Wrenger, Sabine; Faust, Jürgen; Mrestani-Klaus, Carmen; Brandt, Wolfgang; Thielitz, Anja; Neubert, Klaus; Reinhold, Dirk
In: Frontiers in bioscience - Searington, NY, Bd. 13 (2008), Heft 9, S. 3194-3201
Inflammatory bowel diseases: multiple benefits from therapy with dipeptidyl- and alanyl-aminopeptidase inhibitors
Bank, Ute; Bohr, Ulrich R. M.; Reinhold, Dirk; Lendeckel, Uwe; Ansorge, Siegfried; Malfertheiner, Peter; Täger, Michael
In: Frontiers in bioscience - Searington, NY, Bd. 13 (2008), Heft 10, S. 3699-3713
Inhibitors of dipeptidyl peptidase IV-like activity mediate antifibrotic effects in normal and keloid-derived skin fibroblasts
Thielitz, Anja; Vetter, Robert W.; Schultze, Bianca; Wrenger, Sabine; Simeoni, Luca; Ansorge, Siegfried; Neubert, Klaus; Faust, Jürgen; Lindenlaub, Petra; Gollnick, Harald; Reinhold, Dirk
In: The journal of investigative dermatology - New York, NY : Elsevier, Bd. 128 (2008), Heft 4, S. 855-866
DP IV/CD26, APN/CD13 and related enzymes as regulators of T cell immunity: implications for experimental encephalomyelitis and multiple sclerosis
Reinhold, Dirk; Bank, Ute; Täger, Michael; Ansorge, Siegfried; Wrenger, Sabine; Thielitz, Anja; Lendeckel, Uwe; Faust, Jürgen; Neubert, Klaus; Brocke, Stefan
In: Frontiers in bioscience - Searington, NY, Bd. 13 (2008), Heft 6, S. 2356-2363
The ectopeptidases dipeptidyl peptidase IV (DP IV) and aminopeptidase N (APN) and their related enzymes as possible targets in the treatment of skin diseases
Thielitz, Anja; Ansorge, Siegfried; Bank, Ute; Täger, Michael; Wrenger, Sabine; Gollnick, Harald; Reinhold, Dirk
In: Frontiers in bioscience - Searington, NY, Bd. 13 (2008), Heft 6, S. 2364-2375
2007
Inhibitors of dipeptidyl peptidase IV and aminopeptidase N target major pathogenetic steps in acne initiation
Thielitz, Anja; Reinhold, Dirk; Vetter, Robert; Bank, Ute; Helmuth, Martin; Hartig, Roland; Wrenger, Sabine; Wiswedel, Ingrid; Lendeckel, Uwe; Kähne, Thilo; Neubert, Klaus; Faust, Jürgen; Zouboulis, Christos C.; Ansorge, Siegfried; Gollnick, Harald
In: The journal of investigative dermatology - New York, NY : Elsevier, Bd. 127 (2007), Heft 5, S. 1042-1051
Dual inhibition of dipeptidyl peptidase IV and aminopeptidase N suppresses inflammatory immune responses
Reinhold, Dirk; Biton, Aliza; Goihl, Alexander; Pieper, Stefanie; Lendeckel, Uwe; Faust, Jürgen; Neubert, Klaus; Bank, Ute; Täger, Michael; Ansorge, Siegfried; Brocke, Stefan
In: Annals of the New York Academy of Sciences/ New York Academy of Sciences - Hoboken, NJ: Wiley Subscription Services, Bd. 1110 (2007), S. 402-409
A new line immunoassay for the multiparametric detection of antiganglioside autoantibodies in patients with autoimmune peripheral neuropathies
Conrad, Karsten; Schneider, Hauke; Ziemssen, Tjalf; Talaska, Thomas; Reinhold, Dirk; Humbel, Rene-Louis; Roggenbuck, Dirk
In: Autoimmunity ; Pt. A:Basic principles and new diagnostic tools / ed. by M. Eric Gershwin and Yehuda Shoenfeld - Boston, Mass.: Blackwell Publ., Bd. 1109 (2007), S. 256-264
A new line immunoassay for the multiparametric detection of antiganglioside autoantibodies in patients with autoimmune peripheral neuropathies
Conrad, Karsten; Schneider, Hauke; Ziemssen, Tjalf; Talaska, Thomas; Reinhold, Dirk; Humbel, Rene-Louis; Roggenbuck, Dirk
In: Autoimmunity ; Pt. A: Basic principles and new diagnostic tools - Boston, Mass. : Blackwell Publ. ; Shoenfeld, Yehuda, Bd. 1109 (2007), S. 256-264
TGF-[beta]1-mediated control of central nervous system inflammation and autoimmunity through the inhibitory receptor CD26
Preller, Vera; Gerber, Annegret; Wrenger, Sabine; Togni, Mauro; Marguet, Didier; Tadje, Janine; Lendeckel, Uwe; Röcken, Christoph; Faust, Jürgen; Neubert, Klaus; Schraven, Burkhart; Martin, Roland; Ansorge, Siegfried; Brocke, Stefan; Reinhold, Dirk
In: The journal of immunology - Rockville, Md.: American Association of Immunologists, Bd. 178 (2007), 7, S. 4632-4640
Deletion of the LIME adaptor protein minimally affects T and B cell development and function
Grégoire, Claude; Simova, Sarka; Wang, Ying; Sansoni, Amandine; Richelme, Sylvie; Schmidt-Giese, Anja; Simeoni, Luca; Angelisova, Pavla; Reinhold, Dirk; Schraven, Burkhart; Horejsi, Vaclav; Malissen, Bernard; Malissen, Marie
In: European journal of immunology - Weinheim: Wiley, Bd. 37 (2007), 11, S. 3259-3269
TGF-[beta]1-mediated control of central nervous system inflammation and autoimmunity through the inhibitory receptor CD26
Preller, Vera; Gerber, Annegret; Wrenger, Sabine; Togni, Mauro; Marguet, Didier; Tadje, Janine; Lendeckel, Uwe; Röcken, Christoph; Faust, Jürgen; Neubert, Klaus; Schraven, Burkhart; Martin, Roland; Ansorge, Siegfried; Brocke, Stefan; Reinhold, Dirk
In: The journal of immunology - Rockville, Md. : American Association of Immunologists, Bd. 178 (2007), Heft 7, S. 4632-4640
Deletion of the LIME adaptor protein minimally affects T and B cell development and function
Grégoire, Claude; Simova, Sarka; Wang, Ying; Sansoni, Amandine; Richelme, Sylvie; Schmidt-Giese, Anja; Simeoni, Luca; Angelisova, Pavla; Reinhold, Dirk; Schraven, Burkhart; Horejsi, Vaclav; Malissen, Bernard; Malissen, Marie
In: European journal of immunology - Weinheim : Wiley, Bd. 37 (2007), Heft 11, S. 3259-3269
Inhibition of alanyl-aminopeptidase on CD4+CD25+ regulatory T-cells enhances expression of FoxP3 and TGF-[beta]1 and ameliorates acute colitis in mice
Bank, Ute; Tadje, Janine; Täger, Michael; Wolke, Carmen; Bukowska, Alicja; Ittenson, Annelore; Reinhold, Dirk; Helmuth, Martin; Ansorge, Siegfried; Shakespeare, Ann; Vieth, Michael W.R.; Malfertheiner, Peter; Naumann, Michael; Lendeckel, Uwe
In: International journal of molecular medicine - Athens : Spandidos Publications, Bd. 20 (2007), Heft 4, S. 483-492
Dual inhibition of dipeptidyl peptidase IV and aminopeptidase N suppresses inflammatory immune responses
Reinhold, Dirk; Biton, Aliza; Goihl, Alexander; Pieper, Stefanie; Lendeckel, Uwe; Faust, Jürgen; Neubert, Klaus; Bank, Ute; Täger, Michael; Ansorge, Siegfried; Brocke, Stefan
In: Annals of the New York Academy of Sciences - Hoboken, NJ : Wiley Subscription Services, Bd. 1110 (2007), S. 402-409
2006
Immune peptides related to dipeptidyl aminopeptidase IV/CD26
Ansorge, Siegfried; Reinhold, Dirk
In: Handbook of biologically active peptides - Amsterdam: Elsevier, Academic Press; Kastin, Abba J. . - 2006, S. 567-572
Immune peptides related to dipeptidyl aminopeptidase IV/CD26
Ansorge, Siegfried; Reinhold, Dirk
In: Handbook of biologically active peptides - Amsterdam : Elsevier, Academic Press ; Kastin, Abba J. . - 2006, S. 567-572
Dipeptidyl aminopeptidases - basic science and clinical applications
Lendeckel, Uwe; Reinhold, Dirk; Bank, Ute
In: New York: Springer Science + Business Media, 2006, XXIV, 239 S., Ill, graf. Darst. - (Advances in experimental medicine and biology; 575)Kongress: International Conference on Dipeptidyl Aminopeptidases 2 (Magdeburg : 2005.04.13-15)
Dipeptidyl aminopeptidases - basic science and clinical applications
Lendeckel, Uwe; Reinhold, Dirk; Bank, Ute
In: New York: Springer Science + Business Media, 2006, XXIV, 239 S. - (Advances in experimental medicine and biology; 575), ISBN: 978-0-387-29058-4 Kongress: International Conference on Dipeptidyl Aminopeptidases 2 Magdeburg 2005.04.13-15
Attractin, a dipeptidyl peptidase IV/CD26-like enzyme, is expressed on human peripheral blood monocytes and potentially influences monocyte function
Wrenger, Sabine; Faust, Jürgen; Friedrich, Daniel; Hoffmann, Torsten; Hartig, Roland; Lendeckel, Uwe; Kähne, Thilo; Thielitz, Anja; Neubert, Klaus; Reinhold, Dirk
In: Journal of leukocyte biology: cellular and molecular mechanisms of host defense and inflammation / publ. by the Federation of American Societies for Experimental Biology - Bethesda, Md.: FASEB, Bd. 80 (2006), 3, S. 621-629
Triggering endogenous immunosuppressive mechanisms by combined targeting of Dipeptidyl peptidase IV (DPIV/CD26) and Aminopeptidase N (APN/ CD13) - a novel approach for the treatment of inflammatory bowel disease
Bank, Ute; Heimburg, Anke; Helmuth, Martin; Stefin, Sofia; Lendeckel, Uwe; Reinhold, Dirk; Faust, Jürgen; Fuchs, Petra; Sens, Bianca; Neubert, Klaus; Täger, Michael; Ansorge, Siegfried
In: International immunopharmacology - Amsterdam [u.a.]: Elsevier, Bd. 6 (2006), 13/14, S. 1925-1934
Dipeptidyl peptidase IV (DP IV, CD26) and aminopeptidase N (APN, CD13) as regulators of T cell function and targets of immunotherapy in CNS inflammation
Reinhold, Dirk; Biton, Aliza; Pieper, Stefanie; Lendeckel, Uwe; Faust, Jürgen; Neubert, Klaus; Bank, Ute; Täger, Michael; Ansorge, Siegfried; Brocke, Stefan
In: International immunopharmacology - Amsterdam [u.a.] : Elsevier, Bd. 6 (2006), Heft 13/14, S. 1935-1942
Attractin, a dipeptidyl peptidase IV/CD26-like enzyme, is expressed on human peripheral blood monocytes and potentially influences monocyte function
Wrenger, Sabine; Faust, Jürgen; Friedrich, Daniel; Hoffmann, Torsten; Hartig, Roland; Lendeckel, Uwe; Kähne, Thilo; Thielitz, Anja; Neubert, Klaus; Reinhold, Dirk
In: Journal of leukocyte biology - Bethesda, Md. : FASEB, Bd. 80 (2006), Heft 3, S. 621-629
Triggering endogenous immunosuppressive mechanisms by combined targeting of Dipeptidyl peptidase IV (DPIV/CD26) and Aminopeptidase N (APN/ CD13) - a novel approach for the treatment of inflammatory bowel disease
Bank, Ute; Heimburg, Anke; Helmuth, Martin; Stefin, Sofia; Lendeckel, Uwe; Reinhold, Dirk; Faust, Jürgen; Fuchs, Petra; Sens, Bianca; Neubert, Klaus; Täger, Michael; Ansorge, Siegfried
In: International immunopharmacology - Amsterdam [u.a.] : Elsevier, Bd. 6 (2006), Heft 13/14, S. 1925-1934
Normal T-cell development and immune functions in TRIM-deficient mice
Kölsch, Uwe; Arndt, Börge; Reinhold, Dirk; Lindquist, Jonathan A.; Jüling, Nicole; Kliche, Stefanie; Pfeffer, Klaus; Bruyns, Eddy; Schraven, Burkhart; Simeoni, Luca
In: Molecular and cellular biology: MCB / American Society for Microbiology - Washington, DC: American Society for Microbiology, Bd. 26 (2006), Heft 9, S. 3639-3648
Increased concentrations of transforming growth factor [beta]1 and [beta]2 in the plasma of patients with glioblastoma
Schneider, Thomas; Sailer, Michael; Ansorge, Siegfried; Firsching, Raimund; Reinhold, Dirk
In: Journal of neuro-oncology - Dordrecht : Springer, Bd. 79 (2006), Heft 1, S. 61-65
Increased concentrations of transforming growth factor [beta]1 and [beta]2 in the plasma of patients with glioblastoma
Schneider, Thomas; Sailer, Michael; Ansorge, Siegfried; Firsching, Raimund; Reinhold, Dirk
In: Journal of neuro-oncology - Dordrecht: Springer, Bd. 79 (2006), 1, S. 61-65
Normal T-cell development and immune functions in TRIM-deficient mice
Kölsch, Uwe; Arndt, Börge; Reinhold, Dirk; Lindquist, Jonathan A.; Jüling, Nicole; Kliche, Stefanie; Pfeffer, Klaus; Bruyns, Eddy; Schraven, Burkhart; Simeoni, Luca
In: Molecular and cellular biology - Washington, DC : American Society for Microbiology, Bd. 26 (2006), Heft 9, S. 3639-3648
CD26/DP IV in T cell activation and autoimmunity
Preller, Vera; Gerber, Annegret; Togni, Mauro; Wrenger, Sabine; Schraven, Burkhart; Röcken, Christoph; Marguet, Didier; Ansorge, Siegfried; Brocke, Stefan; Reinhold, Dirk
In: Dipeptidyl aminopeptidases - basic science and clinical applications , 1. Ed. - New York : Springer Science + Business Media , 2006, S. 187-193
Dipeptidylpeptidase IV (DPIV) and alanyl-aminopeptidases (AAPs) as a new target complex for treatment of autoimmune and inflammatory diseases - proof of concept in a mouse model of colitis
Bank, Ute; Tadje, Janine; Helmuth, Martin; Stefin, Sofia; Täger, Michael; Wolke, Carmen; Wischeropp, Anke; Ittenson, Annelore; Reinhold, Dirk; Ansorge, Siegfried; Lendeckel, Uwe
In: Dipeptidyl aminopeptidases - New York: Springer Science + Business Media, 2006 . - 2006, S. 143-153
CD26/DP IV in T cell activation and autoimmunity
Preller, Vera; Gerber, Annegret; Togni, Mauro; Wrenger, Sabine; Schraven, Burkhart; Röcken, Christoph; Marguet, Didier; Ansorge, Siegfried; Brocke, Stefan; Reinhold, Dirk
In: Dipeptidyl aminopeptidases - New York: Springer Science + Business Media, 2006 . - 2006, S. 187-193
Dipeptidyl peptidase IV (DP IV, CD26) and aminopeptidase N (APN, CD13) as regulators of T cell function and targets of immunotherapy in CNS inflammation
Biton, Aliza; Bank, Ute; Täger, Michael; Ansorge, Siegfried; Reinhold, Dirk; Lendeckel, Uwe; Brocke, Stefan
In: Dipeptidyl aminopeptidases - New York: Springer Science + Business Media, 2006 . - 2006, S. 177-186
Possible role of DP IV inhibitors in acne therapy
Thielitz, Anja; Reinhold, Dirk; Vetter, Robert; Lendeckel, Uwe; Kähne, Thilo; Bank, Ute; Helmuth, Martin; Neubert, Klaus; Faust, Jürgen; Hartig, Roland; Wrenger, Sabine; Zouboulis, Christos C.; Ansorge, Siegfried; Gollnick, Harald
In: Dipeptidyl aminopeptidases - New York: Springer Science + Business Media, 2006 . - 2006, S. 163-167
Expression of dipeptidyl peptidase IV-like enzymes in human peripheral blood mononuclear cells
Wrenger, Sabine; Guth, Bianca; Schultze, Bianca; Hoffmann, Torsten; Friedrichs, Daniela; Kähne, Thilo; Faust, Jürgen; Neubert, Klaus; Reinhold, Dirk
In: Dipeptidyl aminopeptidases - basic science and clinical applications , 1. Ed. - New York : Springer Science + Business Media , 2006, S. 87-91
Expression of dipeptidyl peptidase IV-like enzymes in human peripheral blood mononuclear cells
Wrenger, Sabine; Guth, Bianca; Schultze, Bianca; Hoffmann, Torsten; Friedrich, Daniel; Kähne, Thilo; Faust, Jürgen; Neubert, Klaus; Reinhold, Dirk
In: Dipeptidyl aminopeptidases - New York: Springer Science + Business Media, 2006 . - 2006, S. 87-91
2005
Soluble vascular endothelial growth factor, soluble VEGF receptor Flt-1 and endothelial function in healthy smokers.
Schmidt-Lucke, Caroline; Belgore, F.; Reinhold, Dirk; Ansorge, Siegfried; Klein, Helmut; Schmidt-Lucke, Jan Andre; Lip, G.
In: Int. J. Cardiol. 100(2005), Nr. 2, S. 207 - 212
2004
Increased blood plasma concentrations of TGF-beta isoforms after treatment with intravenous immunoglobulins (IVIG) in patients with multiple sclerosis.
Reinhold, Dirk; Perlov, E.; Schrecke, Kirstin; Kekow, Joern; Brune, Thomas; Sailer, Michael
In: J. Neuroimmunol. 152(2004), Nr. 1-2, S. 191 - 194
2003
Immunomodulatory effects of zinc.
Reinhold, Dirk; Ansorge, Siegfried; Gruengreiff, K.
In: Bonnekoh, B. (Ed.) ; Gollnick, H. (Ed.): Clinico-experimental advances in dermatological diagnostics and treatment : the proceedings of two scientific workshops, organized in the years 2000 and 2001 by the Department of Dermatology and Venerology, Otto-von-Guericke- University Magdeburg. 1. Aufl. Melsungen : Bibliomed, 2003, S. 157 - 162
Dipeptidyl peptidase IV inhibitors with the N-terminal MXP sequence : structure-activity- relationships.
Faust, J.; Fuchs, P.; Wrenger, Sabine; Reinhold, Dirk; Stoeckel Maschek, A.; Kaehne, Thilo; Ansorge, Siegfried; Neubert, K.
In: Hildebrandt, M. (Ed.) ; Klapp, B. (Ed.) ; ... (Ed.): Dipeptidyl aminopeptidases in health and disease. New York [u.a.] : Kluwer Academic/Plenum Publ., 2003, S. 175 - 179 (Advances in experimental medicine and biology ; 524)
Specific inhibition of dipeptidyl peptidase IV (CD26) enzymatic activity - a new approach to psoriasis therapy?.
Vetter, Robert; Reinhold, Dirk; Buehling, Frank; Lendeckel, Uwe; Born, I.; Faust, J.; Neubert, K.; Ansorge, Siegfried; Gollnick, Harald
In: Bonnekoh, B. (Ed.) ; Gollnick, H. (Ed.): Clinico-experimental advances in dermatological diagnostics and treatment : the proceedings of two scientific workshops, organized in the years 2000 and 2001 by the Department of Dermatology and Venerology, Otto-von-Guericke- University Magdeburg. 1. Aufl. Melsungen : Bibliomed, 2003, S. 113 - 119
Propolis and some of its constituents down-regulate DNA synthesis and inflammatory cytokine production but induce TGF-ß1 production of human immune cells.
Ansorge, S.; Reinhold, Dirk; Lendeckel, Uwe
In: Z. Naturforsch. C 58c(2003), Nr. 7/8, S. 580 - 589
2002
Protein kinase C and ERK activation are required for TFF-peptide-stimulated bronchial epithelial cell migration and tumor necrosis factor-alpha-induced interleukin-6 (IL-6) and IL- 8 secretion.
Graness, Angela; Chwieralski, Caroline; Reinhold, Dirk; Thim, L.; Hoffmann, Werner
In: keine Angabe