Publikationen

2024

Abstract

A study on experimentally induced thrombus formation in JAK2-V617F and Calr-del52 mouse models using ligation of the Inferior Vena Cava (IVC)

Bhuria, Vikas; Böttcher, Martin; Zeremski, Vanja; Müller, Andreas Johann; Mougiakakos, Dimitrios; Fischer, Thomas

In: Blood - Washington, DC : American Society of Hematology, Bd. 144 (2024), Heft Supplement 1, S. 4521-4522

Begutachteter Zeitschriftenartikel

Early-life vitamin A treatment rescues neonatal infection-induced durably impaired tolerogenic properties of celiac lymph nodes

Zou, Mangge; Pezoldt, Jörn; Mohr, Juliane; Philipsen, Lars; Leufgen, Andrea; Cerovic, Vuk; Wiechers, Carolin; Pils, Marina C.; Ortiz, Diego; Hao, Lianxu; Yang, Juhao; Beckstette, Michael; Dupont, Aline; Hornef, Mathias; Dersch, Petra; Strowig, Till; Müller, Andreas Johann; Raila, Jens; Hühn, Jochen

In: Cell reports - Maryland Heights, MO : Cell Press, Bd. 43 (2024), Heft 5, Artikel 114153, insges. 28 S.

Metabolic and ionic control of T cells in asthma endotypes

Franz, Tobias; Stegemann-Koniszewski, Sabine; Schreiber, Jens; Müller, Andreas Johann; Bruder, Dunja; Dudeck, Anne; Boehme, Julia D.; Kahlfuß, Sascha

In: American journal of physiology. Cell physiology - Bethesda, Md. : American Physiological Society, Bd. 327 (2024), Heft 5, S. C1300-C1307

Silver-integrated EDM processing of TiAl6V4 implant material has antibacterial capacity while optimizing osseointegration

Büssemaker, Hilmar; Meinshausen, Ann-Kathrin; Bui, Viet Duc; Döring, Joachim; Voropai, Vadym; Buchholz, Adrian; Müller, Andreas Johann; Harnisch, Karsten; Martin, André; Berger, Thomas; Schubert, Andreas; Bertrand, Jessica

In: Bioactive materials - [Bejing] : KeAi Publishing, Bd. 31 (2024), S. 497-508

Neutrophil-specific expression of JAK2-V617F or CALRmut induces distinct inflammatory profiles in myeloproliferative neoplasia

Haage, Tobias Ronny; Charakopoulos, Emmanouil; Bhuria, Vikas; Baldauf, Conny K.; Korthals, Mark; Handschuh, Juliane; Müller, Peter; Li, Juan; Harit, Kunjan; Nishanth, Gopala; Frey, Stephanie; Böttcher, Martin; Fischer, Klaus-Dieter; Dudeck, Jan; Dudeck, Anne; Lipka, Daniel; Schraven, Burkhart; Green, Tony; Müller, Andreas Johann; Mougiakakos, Dimitrios; Fischer, Thomas

In: Journal of hematology & oncology - London : Biomed Central, Bd. 17 (2024), S. 1-23, Artikel 43, insges. 23 S. [Gesehen am 18.11.2024]

Innate players in Th2 and non-Th2 asthma - emerging roles for the epithelial cell, mast cell, and monocyte/macrophage network

Kotrba, Johanna; Müller, Ilka; Pausder, Alexander; Hoffmann, Aaron; Camp, Belinda; Boehme, Julia D.; Müller, Andreas Johann; Schreiber, Jens; Bruder, Dunja; Kahlfuß, Sascha; Dudeck, Anne; Stegemann-Koniszewski, Sabine

In: American journal of physiology. Cell physiology - Bethesda, Md. : American Physiological Society, Bd. 327 (2024), Heft 6, S. C1373-C1383

Investigating pyroptosis as a mechanism of L. major cell-to-cell spread in the human BLaER1 infection model

Volkmar, Kerren; Jaedtka, Moritz; Baars, Iris; Walber, Bianca; Philipp, Marie-Sophie; Bagola, Katrin; Müller, Andreas Johann; Heine, Holger; Zandbergen, Ger

In: Molecular microbiology - Oxford [u.a.] : Wiley-Blackwell, Bd. 121 (2024), Heft 3, S. 453-469

Dissertation

Die Rolle c-Flip-abängiger NKp46-positiver Zellen in der intestinalen Homöostase

Jänsch, Robert; Müller, Andreas Johann; Tuckermann, Jan Peter Gottfried

In: Magdeburg: Otto-von-Guericke-Universität Magdeburg, Dissertation Universität Magdeburg 2024, 7 ungezählte Blätter, 85 Blätter

2023

Abstract

Neutrophils - not as ready to go as we thought?

Schwendele, Cora; Müller, Andreas Johann

In: European journal of immunology - Weinheim : Wiley-VCH, Bd. 53 (2023), Heft Suppl. 2, S. 361, Artikel P 379

CD4+ T cells eradicate IFN-unresponsive melanomas that resist CD8+ T cell therapy

Kruse, Bastian; Buzzai, Anthony; Shridhar, Naveen; Braun, Andreas; Gellert, Susan; Knauth, Kristin; Peters, Johannes; Mengoni, Miriam; Sluis, Tetje van der; Krone, Anna; Yu, Di; Höhn, Simon; Fu, Yan; Essand, Magnus; Geffers, Robert; Mougiakakos, Dimitrios; Kahlfuß, Sascha; Kashkar, Hamid; Gaffal, Evelyn; Kastenmüller, Wolfgang; Müller, Andreas Johann; Tüting, Thomas

In: The journal of investigative dermatology - Amsterdam : Elsevier, Bd. 143 (2023), Heft 5, Supplement, S. S63, Artikel 366

Dependence of pathogenic T helper cells on lipid receptors during house dust mite allergic airway inflammation

Krone, Anna; Schreiber, Simon; Negele, Jonas; Franz, Tobias; Kotrba, Johanna; Marks, Anna; Roder, Marc; Sammt, Anja; Jantz-Naeem, Nouria; Garbers, Christoph; Geffers, Robert; Schraven, Burkhart; Müller, Andreas Johann; Dudeck, Anne; Kahlfuß, Sascha

In: European journal of immunology - Weinheim : Wiley-VCH, Bd. 53 (2023), Heft Suppl. 2, S. 377, Artikel P 391

An IL-7 dependent rheostat drives hypo-inflammatory monocytes to dampen effector T cell responses in the tissue

Fu, Yan; Toussaint, Christophe; Sauerland, Ina; Philipsen, Lars; Saliba, Antoine; Schüler, Thomas; Müller, Andreas Johann

In: European journal of immunology - Weinheim : Wiley-VCH, Bd. 53 (2023), Heft Suppl. 2, S. 27, Artikel P 21

Begutachteter Zeitschriftenartikel

Leishmania major drives host phagocyte death and cell-to-cell transfer depending on intracellular pathogen proliferation rate

Baars, Iris; Jaedtka, Moritz; Dewitz, Leon-Alexander; Fu, Yan; Franz, Tobias; Mohr, Juliane; Gintschel, Patricia; Berlin, Hannes; Degen, Angelina; Freier, Sandra; Rygol, Stefan; Schraven, Burkhart; Kahlfuß, Sascha; Zandbergen, Ger; Müller, Andreas Johann

In: JCI insight - Ann Arbor, Michigan : JCI Insight, Bd. 8 (2023), Heft 14, Artikel e169020, insges. 20 S.

CD4+ T cell-induced inflammatory cell death controls immune-evasive tumours

Kruse, Bastian; Buzzai, Anthony C.; Shridhar, Naveen; Braun, Andreas; Gellert, Susan; Knauth, Kristin; Pozniak, Joanna; Peters, Johannes; Dittmann, Paulina; Mengoni, Miriam; Sluis, Tetje Cornelia van der; Höhn, Simon; Antoranz, Asier; Krone, Anna; Fu, Yan; Yu, Di; Essand, Magnus; Geffers, Robert; Mougiakakos, Dimitrios; Kahlfuß, Sascha; Kashkar, Hamid; Gaffal, Evelyn; Bosisio, Francesca M.; Bechter, Oliver; Rambow, Florian; Marine, Jean-Christophe; Kastenmüller, Wolfgang; Müller, Andreas Johann; Tüting, Thomas

In: Nature - London [u.a.] : Nature Publ. Group, Bd. 618 (2023), Heft 7967, S. 1033-1040

2022

Abstract

Intratumoral interaction dynamics of CD4+ T cells with myeloid cells during tumor regression

Kruse, Bastian; Buzzai, Anthony; Shridhar, Naveen; Braun, Andreas; Sluis, Tetje van der; Knauth, Kristin; Ruotsalainen, Janne; Gellert, Susan; Benkel, C.; Gaffal, Evelyn; Kahlfuß, Sascha; Müller, Andreas Johann; Tüting, Thomas

In: Experimental dermatology - Oxford : Wiley-Blackwell, Bd. 31 (2022), Heft 2, S. e76-e77, Artikel P165 (OP01/01)

Begutachteter Zeitschriftenartikel

The C5a-C5aR1 complement axis is essential for neutrophil recruitment to draining lymph nodes via high endothelial venules in cutaneous leishmaniasis

Prat-Luri, Borja; Neal, Christopher; Passelli, Katiuska; Ganga, Emma; Amore, Jonas; Firmino-Cruz, Luan; Petrova, Tatiana V.; Müller, Andreas Johann; Tacchini-Cottier, Fabienne

In: Cell reports - Maryland Heights, MO: Cell Press, 2012, Bd. 39 (2022), 5, insges. 21 S.

A photoconvertible reporter system for bacterial metabolic activity reveals that Staphylococcus aureus enters a dormant-like state to persist within macrophages

Lang, Julia C.; Seiß, Elena Anne; Moldovan, Adriana; Müsken, Mathias; Sauerwein, Till; Fraunholz, Martin; Müller, Andreas Johann; Goldmann, Oliver; Medina, Eva

In: mBio - Washington, DC: American Society for Microbiology, 2010, Bd. 13 (2022), 5, insges. 15 S.

Ionic mitigation of CD4 + T cell metabolic fitness, Th1 central nervous system autoimmunity and Th2 asthmatic airway inflammation by therapeutic zinc

Krone, Anna; Fu, Yanpeng; Schreiber, Simon; Kotrba, Johanna; Borde, Loisa; Nötzold, Aileen; Thurm, Christoph; Negele, Jonas; Franz, Tobias; Stegemann-Koniszewski, Sabine; Schreiber, Jens; Garbers, Christoph; Shukla, Aniruddh; Geffers, Robert; Schraven, Burkhart; Reinhold, Dirk; Dudeck, Anne; Reinhold, Annegret; Müller, Andreas Johann; Kahlfuß, Sascha

In: Scientific reports - [London] : Macmillan Publishers Limited, part of Springer Nature, Bd. 12 (2022), Artikel 1943, insges. 14 S.

Human 3D airway tissue models for real-time microscopy - visualizing respiratory virus spreading

Möckel, Marion; Baldok, Nino; Walles, Thorsten; Hartig, Roland; Müller, Andreas Johann; Reichl, Udo; Genzel, Yvonne; Walles, Heike; Wiese-Rischke, Cornelia

In: Cells - Basel : MDPI, Bd. 11 (2022), Heft 22, Artikel 3634, insges. 21 S.

Pleiotropic effects of antibiotics on T cell metabolism and T cell-mediated immunity

Franz, Tobias; Negele, Jonas; Bruno, Philipp; Böttcher, Martin; Mitchell-Flack, Marisa; Reemts, Lea; Krone, Anna; Mougiakakos, Dimitrios; Müller, Andreas Johann; Zautner, Andreas Erich; Kahlfuß, Sascha

In: Frontiers in microbiology - Lausanne: Frontiers Media, 2010, Bd. 13 (2022), insges. 13 S.

Dissertation

The role of nitric oxide controlling intracellular pathogen, a link between proliferation inhibition and permissive host cell recruitment

Alabdullah, Mohamad; Müller, Andreas Johann

In: Magdeburg: Universitätsbibliothek, Dissertation Otto-von-Guericke-Universität Magdeburg, Fakultät für Naturwissenschaften 2022, 1 Online-Ressource (VIII, 98 Seiten, 4,32 MB) [Literaturverzeichnis: Seite 87-97][Literaturverzeichnis: Seite 87-97]

2021

Abstract

Early-life vitamin A treatment rescues neonatal infection-induced long-lastingly impaired lymph node operativeness

Zou, Mangge; Pezoldt, Jörn; Raila, Jens; Wiechers, Carolin; Mohr, Juliane; Yang, Juhao; Beckstette, Michael; Hao, Lianxu; Dupont, Aline; Hornef, Mathias; Strowig, Till; Dersch, Petra; Müller, Andreas Johann; Hühn, Jochen

In: European journal of immunology - Weinheim: Wiley-VCH, 1971, Bd. 51 (2021), Suppl. 1, S. 75

Begutachteter Zeitschriftenartikel

Severe traumatic injury induces phenotypic and functional changes of neutrophils and monocytes

Janicova, Andrea; Becker, Nils; Xu, Baolin; Simic, Marija; Noack, Laurens; Wagner, Nils; Müller, Andreas Johann; Bertrand, Jessica; Marzi, Ingo; Relja, Borna

In: Journal of Clinical Medicine - Basel : MDPI, Bd. 10 (2021), Heft 18, Artikel 4139, insges. 19 S.

Maternal B cell-intrinsic MyD88 signaling mediates LPS-driven intrauterine fetal death

Busse, Mandy; Plenagl, Susanne; Campe, Norina Kim Jutta; Müller, Andreas Johann; Tedford, Kerry; Schumacher, Anne; Zenclussen, Ana Claudia

In: Cells - Basel: MDPI, 2012, Bd. 10 (2021), 10, insges. 15 S.

Interleukin-11 receptor expression on monocytes is dispensable for their recruitment and pathogen uptake during Leishmania major infection

Baars, Iris; Lokau, Juliane; Sauerland, Ina; Müller, Andreas Johann; Garbers, Christoph

In: Cytokine - Oxford [u.a.]: Elsevier, Bd. 148 (2021)

Directional mast cell degranulation of tumor necrosis factor into blood vessels primes neutrophil extravasation

Dudeck, Jan; Kotrba, Johanna; Immler, Roland Thomas; Hoffmann, Aaron; Voss, Martin; Alexakē, Basileia-Ismēnē; Morton, Lorena; Jahn, Stephan René; Katsoulis-Dimitriou, Konstantinos; Winzer, Simon; Kollias, Georg; Fischer, Thomas; Nedospasov, Sergei A.; Dunay, Ildikò Rita; Chavakis, Triantafyllos; Müller, Andreas Johann; Schraven, Burkhart; Sperandio, Markus; Dudeck, Anne

In: Immunity - [Cambridge, Mass.]: Cell Press, Bd. 54 (2021), 3, S. 468-483.e5

Aspect ratio of nano/microstructures determines Staphylococcus aureus adhesion on PET and titanium surfaces

Meinshausen, Ann-Kathrin; Herbster, Maria; Zwahr, Christoph; Soldera, Marcos; Müller, Andreas Johann; Halle, Thorsten; Lasagni, Andrés Fabián; Bertrand, Jessica

In: Journal of applied microbiology - Oxford [u.a.] : Wiley-Blackwell, Bd. 131 (2021), Heft 3, S. 1498-1514

Ly6G deficiency alters the dynamics of neutrophil recruitment and pathogen capture during Leishmania major skin infection

Kleinholz, Corinna L.; Riek-Burchardt, Monika; Seiß, Elena Anne; Amore, Jonas; Gintschel, Patricia; Philipsen, Lars; Bousso, Philippe; Relja, Borna; Schraven, Burkhart; Handschuh, Juliane; Mohr, Juliane; Müller, Andreas Johann

In: Scientific reports - [London]: Macmillan Publishers Limited, part of Springer Nature, 2011, Bd. 11 (2021), insges. 12 S.

Nitric oxide controls proliferation of Leishmania major by inhibiting the recruitment of permissive host cells

Formaglio, Pauline; Alabdullah, Mohamad; Siokis, Anastasios; Handschuh, Juliane; Sauerland, Ina; Fu, Yan; Krone, Anna; Gintschel, Patricia; Stettin, Juliane; Heyde, Sandrina; Mohr, Juliane; Philipsen, Lars; Schröder, Anja; Robert, Philippe A.; Zhao, Gang; Khailaie, Sahamoddin; Dudeck, Anne; Bertrand, Jessica; Späth, Gerald F.; Kahlfuß, Sascha; Bousso, Philippe; Schraven, Burkhart; Hühn, Jochen; Binder, Sebastian; Meyer-Hermann, Michael; Müller, Andreas Johann

In: Immunity - [Cambridge, Mass.] : Cell Press, Bd. 54 (2021), Heft 12, S. 2724-2739.e10

2020

Begutachteter Zeitschriftenartikel

Fibrosis and immune cell infiltration are separate events regulated by cell-specific receptor Notch3 expression

Brandt, Sabine; Ballhause, Tobias Malte; Bernhardt, Anja; Becker, Annika; Salaru, Delia Lidia; Le-Deffge, Hien Minh; Fehr, Alexander; Fu, Yanpeng; Philipsen, Lars; Djudjaj, Sonja; Müller, Andreas Johann; Kramann, Rafael; Ibrahim, Mahmoud; Geffers, Robert; Siebel, Chris; Isermann, Berend; Heidel, Florian; Lindquist, Jonathan A.; Mertens, Peter Rene

In: Journal of the American Society of Nephrology - Washington, DC : American Society of Nephrology, Bd. 31 (2020), Heft 11, S. 2589-2608

TLR7 sensing by neutrophils is critical for the control of cutaneous leishmaniasis

Regli, Ivo B.; Passelli, Katiuska; Martínez-Salazar, Berenice; Amore, Jonas; Hurrell, Benjamin P.; Müller, Andreas Johann; Tacchini-Cottier, Fabienne

In: Cell reports - Maryland Heights, MO: Cell Press, 2012, Vol. 31.2020, Art.-Nr. 107746, insgesamt 18 Seiten

Antibacterial coating of Ti-6Al-4V surfaces using silver nano-powder mixed electrical discharge machining

Bui, Viet D.; Mwangi, James Wamai; Meinshausen, Ann-Kathrin; Müller, Andreas Johann; Bertrand, Jessica; Schubert, Andreas

In: Surface and coatings technology - Amsterdam [u.a.]: Elsevier Science, Bd.383.2020, Art.-Nr. 125254

IL-7 derived from lymph node fibroblastic reticular cells is dispensable for naive T cell homeostasis but crucial for central memory T cell survival

Knop, Laura; Deiser, Katrin; Bank, Ute; Witte, Amelie; Mohr, Juliane; Philipsen, Lars; Fehling, Hans J.; Müller, Andreas Johann; Kalinke, Ulrich; Schüler, Thomas

In: European journal of immunology - Weinheim: Wiley-VCH, 1971, Bd. 50 (2020), 6, S. 846-857

From the cradle to the grave of an infection - host-pathogen interaction visualized by intravital microscopy

Handschuh, Juliane; Amore, Jonas; Müller, Andreas Johann

In: Cytometry / A - Hoboken, NJ: Wiley-Liss, 2003, Bd. 97 (2020), 5, S. 458-470

2019

Abstract

Unraveling pathogen proliferation-related signaling pathways in Leishmania major-infected monocytes in vivo

Fu, Yan; Heyde, Sandrina; Vafadarnejad, Ehsan; Gröger, Nicole; Dolowschiak, Tamas; Joller, Nicole Christine; Saliba, Antoine-Emmanuel; Müller, Andreas Johann

In: European journal of immunology: basic, clinical, translational - Weinheim: Wiley-VCH, 1971, Bd. 49.2019, Suppl. 3, P1345, S. 528

Regulating microvesicle transport at the immunological synapse

Ham, Marco; Amsberg, Nicole; Reinking, Janne; Philipsen, Lars; Müller, Andreas Johann; Hühn, Jochen; Schraven, Burkhart; Jänsch, Lothar

In: European journal of immunology: basic, clinical, translational - Weinheim: Wiley-VCH, 1971, Bd. 49.2019, Suppl. 1, P379, Seite 281

Inflammatory CD11c+ monocytes constitute a main reservoir for high proliferation and cell-to-cell transmission of Leishmania major

Heyde, Sandrina; Philipsen, Lars; Formaglio, Pauline; Fu, Yan; Baars, Iris; Höbbel, Guido; Kleinholz, Corinna L.; Seiß, Elena Anne; Stettin, Juliane; Gintschel, Patricia; Dudeck, Anne; Bousso, Philippe; Schraven, Burkhart; Müller, Andreas Johann

In: European journal of immunology: basic, clinical, translational - Weinheim: Wiley-VCH, 1971, Bd. 49.2019, Suppl. 3, P0943, S. 1195

Begutachteter Zeitschriftenartikel

Longitudinal proliferation mapping in vivo reveals NADPH oxidase-mediated dampening of Staphylococcus aureus growth rates within neutrophils

Seiß, Elena Anne; Krone, Anna; Formaglio, Pauline; Goldmann, Oliver; Engelmann, Susanne; Schraven, Burkhart; Medina, Eva; Müller, Andreas Johann

In: Scientific reports - [London]: Macmillan Publishers Limited, part of Springer Nature, 2011, Bd. 9.2019, Art.-Nr. 5703, insges. 10 S.

Dissertation

Characterization of Staphylococcus aureus skin infection using a new in vivo proliferation biosensor

Seiß, Elena Anne; Müller, Andreas Johann

In: Magdeburg, Dissertation Otto-von-Guericke-Universität Magdeburg, Fakultät für Naturwissenschaften 2019, X, 153 Seiten [Literaturverzeichnis: Seite 107-130][Literaturverzeichnis: Seite 107-130]

2018

Abstract

Filamin A phosphorylation at serine 2152 by the serine/threonine kinase Ndr2 controls TCR-induced LFA-1 activation in T cells

Mix, Charlie; Waldt, Natalie; Seifert, Anke; Demiray, Yunus Emre; Reichardt, Peter; Reinhold, Annegret; Freund, Christian; Müller, Andreas Johann; Schraven, Burkhart; Stork, Oliver; Kliche, Stefanie

In: European journal of immunology - Weinheim : Wiley-VCH - Bd. 49.2019, Suppl. 1, P214, Seite 185-186

Begutachteter Zeitschriftenartikel

JAK2-V617F promotes venous thrombosis through β1/β2 integrin activation

Edelmann, Bärbel; Gupta, Nibedita; Schnöder, Tina; Oelschlegel, Anja Maria; Shahzad, Khurrum; Goldschmidt, Jürgen; Philipsen, Lars; Weinert, Sönke; Ghosh, Aniket; Saalfeld, Felix C.; Nimmagadda, Subbaiah Chary; Müller, Peter; Braun-Dullaeus, Rüdiger C.; Mohr, Juliane; Wolleschak, Denise; Kliche, Stefanie; Amthauer, Holger; Heidel, Florian; Schraven, Burkhart; Isermann, Berend; Müller, Andreas Johann; Fischer, Thomas

In: The journal of clinical investigation - Ann Arbor, Mich.: ASCJ, 1924, Bd. 128 (2018), 10, S. 4359-4371

Cold shock Y-box binding protein-1 acetylation status in monocytes is associated with systemic inflammation and vascular damage

Ewert, Lara; Fischer, Anja; Brandt, Sabine; Scurt, Florian Gunnar; Philipsen, Lars; Müller, Andreas Johann; Girndt, Matthias; Zenclussen, Ana Claudia; Lindquist, Jonathan A.; Gorny, Xenia; Mertens, Peter Rene

In: Atherosclerosis - Amsterdam [u.a.] : Elsevier Science, Bd. 278 (2018), S. 156-165

Beware the intruder - real time observation of infiltrated neutrophils and neutrophil-Microglia interaction during stroke in vivo

Neumann, Jens; Henneberg, Sophie; Kenne, Susanne; Nolte, Niklas; Müller, Andreas Johann; Schraven, Burkhart; Görtler, Michael; Reymann, Klaus G.; Gunzer, Matthias; Riek-Burchardt, Monika

In: PLOS ONE - San Francisco, California, US: PLOS, 2006, Bd. 13.2018, 3, Art.-Nr. e0193970, insges. 9 S.

CD11c-expressing Ly6C+CCR2+ monocytes constitute a reservoir for efficient Leishmania proliferation and cell-to-cell transmission

Heyde, Sandrina; Philipsen, Lars; Formaglio, Pauline; Fu, Yan; Baars, Iris; Höbbel, Guido; Kleinholz, Corinna L.; Seiß, Elena Anne; Stettin, Juliane; Gintschel, Patricia; Dudeck, Anne; Bousso, Philippe; Schraven, Burkhart; Müller, Andreas Johann

In: PLoS pathogens/ Public Library of Science - Lawrence, Kan.: PLoS, 2005, Bd. 14.2018, 10, Art.-Nr. e1007374, insges. 30 S.

Filamin A phosphorylation at serine 2152 by the serine/threonine kinase Ndr2 controls TCR-induced LFA-1 activation in T cells

Waldt, Natalie; Seifert, Anke; Demiray, Yunus Emre; Devroe, Eric; Turk, Benjamin E.; Reichardt, Peter; Mix, Charlie; Reinhold, Annegret; Freund, Christian; Müller, Andreas Johann; Schraven, Burkhart; Stork, Oliver; Kliche, Stefanie

In: Frontiers in immunology - Lausanne : Frontiers Media - Bd. 9.2018, Art.-Nr. 2852, insges. 16 S.

2017

Abstract

Dynein light intermediate chain 1 (LIC1) in T cell signalling and immunological synapse organisation of Tregs

Amsberg, Nicole; Ham, Marco; Kliche, Stefanie; Philipsen, Lars; Müller, Andreas Johann; Falk, Christine Susanne; Hühn, Jochen; Jänsch, Lothar

In: European journal of immunology - Weinheim: Wiley, 1971, Bd. 47.2017, Suppl. 2, P369, S. 268

c-MET dependent neutrophil responses limit anti-tumoral T cell expansion and immunotherapy of cancer

Glodde, Nicole Erika; Bald, Tobias; Boorn-Konijnenberg, Debby; Szczepanski, Sabrina; Brandes, Maria; Eickhoff, Sarah; Shridhar, Naveen; Hinze, Daniel; Rogava, Meri; Sluis, Tetje; Ruotsalainen, Janne; Gaffal, Evelyn; Landsberg, Jennifer Caroline; Ludwig, Kerstin; Riek-Burchardt, Monika; Müller, Andreas Johann; Janzen, Viktor; Kastenmüller, Wolfgang; Mazzone, Massimiliano; Tüting, Thomas; Hölzel, Michael

In: Experimental dermatology: the official journal of the European Immunodermatology Society - Oxford: Wiley-Blackwell, 1992, Bd. 26.2017, 3, P219 (OP01/03), S. E93-E94

Begutachteter Zeitschriftenartikel

TCR signalling network organization at the immunological synapses of murine regulatory T cells

Ham, Marco; Teich, René; Philipsen, Lars; Niemz, Jana; Amsberg, Nicole; Wissing, Josef; Nimtz, Manfred; Gröbe, Lothar; Kliche, Stefanie; Thiel, Nadine; Klawonn, Frank; Hubo, Mario; Jonuleit, Helmut; Reichardt, Peter; Müller, Andreas Johann; Hühn, Jochen; Jänsch, Lothar

In: European journal of immunology: basic, clinical, translational - Weinheim: Wiley-VCH, 1971, Bd. 47 (2017), 12, S. 2043-2058

D120 and K152 within the PH domain of T cell adapter SKAP55 regulate plasma membrane targeting of SKAP55 and LFA-1 affinity modulation in human T lymphocytes

Witte, Amelie; Meineke, Bernhard; Sticht, Jana; Philipsen, Lars; Kuropka, Benno; Müller, Andreas Johann; Freund, Christian; Schraven, Burkhart; Kliche, Stefanie

In: Molecular and cellular biology - London : Taylor & Francis - Bd. 37.2017, 7, Seite e.00509-e.00516

Reactive neutrophil responses dependent on the receptor tyrosine kinase c-MET limit cancer immunotherapy

Glodde, Nicole Erika; Bald, Tobias; Boorn-Konijnenberg, Debby; Nakamura, Kyohei; ODonnell, Jake S.; Szczepanski, Sabrina; Brandes, Maria; Eickhoff, Sarah; Das, Indrajit; Shridhar, Naveen; Hinze, Daniel; Rogava, Meri; Sluis, Tetje C.; Ruotsalainen, Janne J.; Gaffal, Evelyn; Landsberg, Jennifer Caroline; Ludwig, Kerstin U.; Wilhelm, Christoph; Riek-Burchardt, Monika; Müller, Andreas Johann; Gebhardt, Christoffer; Scolyer, Richard A.; Long, Georgina; Janzen, Viktor; Teng, Michele W.L.; Kastenmüller, Wolfgang; Mazzone, Massimiliano; Smyth, Mark J.; Tüting, Thomas; Hölzel, Michael

In: Immunity - [Cambridge, Mass.]: Cell Press, Bd. 47 (2017), 4, S. 789-802

Targeted antigen delivery to dendritic cells elicits robust antiviral T cell-mediated immunity in the liver

Volckmar, Julia; Gereke, Marcus; Ebensen, Thomas; Riese, Peggy; Philipsen, Lars; Lienenklaus, Stefan; Wohlleber, Dirk; Klopfleisch, Robert; Stegemann-Koniszewski, Sabine; Müller, Andreas Johann; Gruber, Achim D.; Knolle, Percy A.; Guzmán, Carlos; Bruder, Dunja

In: Scientific reports - [London]: Macmillan Publishers Limited, part of Springer Nature, 2011, Bd. 7.2017, Art.-Nr. 43985, insges. 14 S.

De novo phosphorylation and conformational opening of the tyrosine kinase Lck act in concert to initiate T cell receptor signaling

Philipsen, Lars; Reddycherla, Amarendra Varma; Hartig, Roland; Gumz, Janine; Kästle, Matthias; Kritikos, Andreas; Poltorak, Mateusz Pawel; Prokazov, Yury; Turbin, Evgeny; Weber, André; Zuschratter, Werner; Schraven, Burkhart; Simeoni, Luca; Müller, Andreas Johann

In: Science signaling: the signal transduction knowledge environment - Washington, DC [u.a.]: Assoc., Bd. 10.2017, 462, insges. 14 S.

Frontline Science - Leishmania mexicana amastigotes can replicate within neutrophils

Hurrell, Benjamin P.; Beaumann, Manon; Heyde, Sandrina; Regli, Ivo B.; Müller, Andreas Johann; Tacchini-Cottier, Fabienne

In: Journal of leukocyte biology: JLB - Hoboken, NJ: Wiley, Bd. 102 (2017), 5, S. 1187-1198

Signal integration at the PI3K-p85-XBP1 hub endows coagulation protease activated protein C with insulin-like function

Madhusudhan, Thati; Wang, Hongjie; Ghosh, Sanchita; Dong, Wei; Kumar, Varun; Al-Dabet, Moh’d Mohanad; Manoharan, Jayakumar; Nazir, Sumra; Elwakiel, Ahmed; Bock, Fabian; Kohli, Shrey; Marquardt, Andi; Sögüt, Ibrahim; Shahzad, Khurrum; Müller, Andreas J.; Esmon, Charles T.; Nawroth, Peter Paul; Reiser, Jochen; Chavakis, Triantafyllos; Ruf, Wolfram; Isermann, Berend

In: Blood - Washington, DC : American Society of Hematology, Bd. 130 (2017), Heft 12, S. 1445-1455, insges. 11 S.

2016

Begutachteter Zeitschriftenartikel

Chronic Toxoplasma gondii infection enhances [beta]-amyloid phagocytosis and clearance by recruited monocytes

Möhle, Luisa; Israel, Nicole; Paarmann, Kristin; Krohn, Markus; Pietkiewicz, Sabine; Müller, Andreas Johann; Lavrik, Inna N.; Buguliskis, Jeffrey S.; Schott, Björn H.; Schlüter, Dirk; Gundelfinger, Eckart D.; Montag, Dirk; Seifert, Ulrike; Pahnke, Jens; Dunay, Ildikò Rita

In: Acta Neuropathologica Communications - London : Biomed Central - Bd. 4.2016, Art.-Nr. 25, insges. 19 S.

2015

Begutachteter Zeitschriftenartikel

Rapid sequestration of Leishmania mexicana by neutrophils contributes to the development of chronic lesion

Hurrell, Benjamin P.; Schuster, Steffen; Grün, Eva; Coutaz, Manuel; Williams, Roderick A.; Held, Werner; Malissen, Bernard; Malissen, Marie; Yousefi, Shida; Simon, Hans-Uwe; Müller, Andreas Johann; Tacchini-Cottier, Fabienne

In: PLoS pathogens/ Public Library of Science - Lawrence, Kan.: PLoS, Bd. 11.2015, 5, Art.-Nr. e1004929, insges. 23 S.

2014

Abstract

Phagocytosis of Abeta by infiltrating myeloid cells in a mouse model of Alzheimer's disease

Möhle, Luisa; Müller, Andreas Johann; Lavrik, Inna N.; Pahnke, Jens; Dunay, Ildikò Rita

In: Journal of neuroimmunology: official journal of the International Society for Neuroimmunology - Amsterdam [u.a.]: Elsevier Science, 1981, Bd. 275 (2014), 1/2, S. 120

Begutachteter Zeitschriftenartikel

Collective nitric oxide production provides tissue-wide immunity during Leishmania infection

Olekhnovitch, R.; Ryffel, B.; Müller, A.J.; Bousso, P.

In: Journal of Clinical Investigation, Vol. 124, 2014, Issue 4, S. 1711-1722, ISSN 00219738, 10.1172/JCI72058

2013

Begutachteter Zeitschriftenartikel

NADPH Oxidase Deficient Mice Develop Colitis and Bacteremia upon Infection with Normally Avirulent, TTSS-1- and TTSS-2-Deficient Salmonella Typhimurium

Felmy, B.; Songhet, P.; Slack, E.M.C.; Müller, A.J.; Kremer, M.; Van Maele, L.; Cayet, D.; Heikenwalder, M.; Sirard, J.-C.; Hardt, W.-D.

In: PLoS ONE, Vol. 8, 2013, Issue 10, ISSN 19326203, 10.1371/journal.pone.0077204

Photoconvertible pathogen labeling reveals nitric oxide control of leishmania major infection in vivo via dampening of parasite metabolism

Müller, A.J.; Aeschlimann, S.; Olekhnovitch, R.; Dacher, M.; Späth, G.F.; Bousso, P.

In: Cell Host and Microbe, Vol. 14, 2013, Issue 4, S. 460-467, ISSN 19313128, 10.1016/j.chom.2013.09.008

2012

Begutachteter Zeitschriftenartikel

CD4 + T Cells Rely on a Cytokine Gradient to Control Intracellular Pathogens beyond Sites of Antigen Presentation

Müller, A.J.; Filipe-Santos, O.; Eberl, G.; Aebischer, T.; Späth, G.F.; Bousso, P.

In: Immunity, Vol. 37, 2012, Issue 1, S. 147-157, ISSN 10747613, 10.1016/j.immuni.2012.05.015

How many dendritic cells are required to initiate a T-cell response?

Celli, S.; Day, M.; Müller, A.J.; Molina-Paris, C.; Lythe, G.; Bousso, P.

In: Blood, Vol. 120, 2012, Issue 19, S. 3945-3948, ISSN 00064971, 10.1182/blood-2012-01-408260

Salmonella gut invasion involves TTSS-2-dependent epithelial traversal, basolateral exit, and uptake by epithelium-sampling lamina propria phagocytes

Müller, A.J.; Kaiser, P.; Dittmar, K.E.J.; Weber, T.C.; Haueter, S.; Endt, K.; Songhet, P.; Zellweger, C.; Kremer, M.; Fehling, H.-J.; Hardt, W.-D.

In: Cell Host and Microbe, Vol. 11, 2012, Issue 1, S. 19-32, ISSN 19313128, 10.1016/j.chom.2011.11.013

2011

Begutachteter Zeitschriftenartikel

Stromal IFN-γr-signaling modulates goblet cell function during salmonella Typhimurium infection

Songhet, P.; Barthel, M.; Stecher, B.; Müller, A.J.; Kremer, M.; Hansson, G.C.; Hardt, W.-D.

In: PLoS ONE, Vol. 6, 2011, Issue 7, ISSN 19326203, 10.1371/journal.pone.0022459

2010

Begutachteter Zeitschriftenartikel

In macrophages, caspase-1 activation by SopE and the type III secretion system-1 of s. Typhimurium can proceed in the absence of flagellin

Hoffmann, C.; Galle, M.; Dilling, S.; Käppeli, R.; Müller, A.J.; Songhet, P.; Beyaert, R.; Hardt, W.-D.

In: PLoS ONE, Vol. 5, 2010, Issue 8, ISSN 19326203, 10.1371/journal.pone.0012477

Antibodies protect against intracellular bacteria by Fc receptor-mediated lysosomal targeting

Joller, N.; Weber, S.S.; Müller, A.J.; Spörri, R.; Selchow, P.; Sander, P.; Hilbi, H.; Oxenius, A.

In: Proceedings of the National Academy of Sciences of the United States of America, Vol. 107, 2010, Issue 47, S. 20441-20446, ISSN 00278424, 10.1073/pnas.1013827107

Host-specific symbiotic requirement of BdeAB, a RegR-controlled RND-type efflux system in Bradyrhizobium japonicum

Lindemann, A.; Koch, M.; Pessi, G.; Müller, A.J.; Balsiger, S.; Hennecke, H.; Fischer, H.-M.

In: FEMS Microbiology Letters, Vol. 312, 2010, Issue 2, S. 184-191, ISSN 03781097, 10.1111/j.1574-6968.2010.02115.x

Caspase-1 activation via Rho GTPases: A common theme in mucosal infections?

Müller, A.J.; Hoffmann, C.; Hardt, W.-D.

In: PLoS Pathogens, Vol. 6, 2010, Issue 2, ISSN 15537366, 10.1371/journal.ppat.1000795

2009

Begutachteter Zeitschriftenartikel

Accelerated type III secretion system 2-dependent enteropathogenesis by a Salmonella enterica serovar enteritidis PT4/6 strain

Suar, M.; Periaswamy, B.; Songhet, P.; Misselwitz, B.; Müller, A.; Käppeli, R.; Kremer, M.; Heikenwalder, M.; Hardt, W.-D.

In: Infection and Immunity, Vol. 77, 2009, Issue 9, S. 3569-3577, ISSN 00199567, 10.1128/IAI.00511-09

The S. Typhimurium Effector SopE Induces Caspase-1 Activation in Stromal Cells to Initiate Gut Inflammation

Müller, A.J.; Hoffmann, C.; Galle, M.; Van Den Broeke, A.; Heikenwalder, M.; Falter, L.; Misselwitz, B.; Kremer, M.; Beyaert, R.; Hardt, W.-D.

In: Cell Host and Microbe, Vol. 6, 2009, Issue 2, S. 125-136, ISSN 19313128, 10.1016/j.chom.2009.07.007

2008

Begutachteter Zeitschriftenartikel

Microbe sampling by mucosal dendritic cells is a discrete, MyD88-independent step in ΔinvG S. Typhimurium colitis

Hapfelmeier, S.; Müller, A.J.; Stecher, B.; Kaiser, P.; Barthel, M.; Endt, K.; Eberhard, M.; Robbiani, R.; Jacobi, C.A.; Heikenwalder, M.; Kirschning, C.; Jung, S.; Stallmach, T.; Kremer, M.; Hardt, W.-D.

In: Journal of Experimental Medicine, Vol. 205, 2008, Issue 2, S. 437-450, ISSN 00221007, 10.1084/jem.20070633

2007

Begutachteter Zeitschriftenartikel

Two newly identified SipA domains (F1, F2) steer effector protein localization and contribute to Salmonella host cell manipulation

Schlumberger, M.C.; Käppeli, R.; Wetter, M.; Müller, A.J.; Misselwitz, B.; Dilling, S.; Kremer, M.; Hardt, W.-D.

In: Molecular Microbiology, Vol. 65, 2007, Issue 3, S. 741-760, ISSN 0950382X, 10.1111/j.1365-2958.2007.05823.x

2005

Begutachteter Zeitschriftenartikel

Real-time imaging of type III secretion: Salmonella SipA injection into host cells

Schlumberger, M.C.; Müller, A.J.; Ehrbar, K.; Winnen, B.; Duss, I.; Stecher, B.; Hardt, W.-D.

In: Proceedings of the National Academy of Sciences of the United States of America, Vol. 102, 2005, Issue 35, S. 12548-12553, ISSN 00278424, 10.1073/pnas.0503407102

The Salmonella Pathogenicity Island (SPI)-2 and SPI-1 type III secretion systems allow Salmonella serovar typhimurium to trigger colitis via MyD88-dependent and MyD88-independent mechanisms

Hapfelmeier, S.; Stecher, B.; Barthel, M.; Kremer, M.; Müller, A.J.; Heikenwalder, M.; Stallmach, T.; Hensel, M.; Pfeffer, K.; Akira, S.; Hardt, W.-D.

In: Journal of Immunology, Vol. 174, 2005, Issue 3, S. 1675-1685, ISSN 00221767

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