Publikationen
2025
SLAMF7 (CD319) on activated CD8+ T cells transduces environmental cues to initiate cytotoxic effector cell responses
Lingel, Holger; Fischer, Laura; Remstedt, Sven; Kuropka, Benno; Philipsen, Lars; Han, Irina; Sander, Jan-Erik; Freund, Christian; Arra, Aditya; Brunner-Weinzierl, Monika
In: Cell death and differentiation - [London] : Springer Nature, Bd. 32 (2025), Heft 3, S. 561-572
PD1+ innate lymphoid cells 3 predict JAK-dependent inflammation in rheumatoid arthritis
Arra, Aditya; Vogel, Katrin; Han, Irina Han; Behrendt, Christine; Dunay, Ildikò Rita; Häupl, Thomas; Feist, Eugen; Brunner-Weinzierl, Monika
In: Journal of autoimmunity - [Amsterdam] : Elsevier, Bd. 154 (2025), Artikel 103424, insges. 11 S.
Long-term increase in soluble interleukin-6 receptor levels in convalescents after mild COVID-19 infection
Lokau, Juliane; Garbers, Yvonne; Vicente, Manuel M.; Dittrich, Anna; Meltendorf, Stefan; Lingel, Holger; Münster-Kühnel, Anja K.; Brunner-Weinzierl, Monika; Garbers, Christoph
In: Frontiers in immunology - Lausanne : Frontiers Media, Bd. 15 (2025), Artikel 1488745, insges. 13 S.
2024
Effective assessment of CD4+ T cell immunodominance patterns - impact of antigen processing and HLA restriction
Álvaro-Benito, Miguel; Abualrous, Esam T.; Lingel, Holger; Meltendorf, Stefan; Holzapfel, Jakob; Sticht, Jana; Kuropka, Benno; Clementi, Cecilia; Kuppler, Frank; Brunner-Weinzierl, Monika; Freund, Christian
In: bioRxiv beta - Cold Spring Harbor : Cold Spring Harbor Laboratory, NY . - 2024, insges. 25 S.
2023
SLAMF7 (CD319) lowers the threshold for differentiation commitment of cytotoxic T lymphocytes
Lingel, Holger; Arra, Aditya; Kuropka, Benno; Remstedt, Sven; Philipsen, Lars; Freund, Christian; Brunner-Weinzierl, Monika
In: European journal of immunology - Weinheim : Wiley-VCH, Bd. 53 (2023), Heft Suppl. 2, S. 148, Artikel O 32
Proteomic profiling and cytokine analysis reveals molecular signatures and inflammatory factors associated with thrombosis in JAK2-V617F positive myeloproliferative neoplasm (MPN) cohorts
Bhuria, Vikas; Ham, Marco Adrianus; Vogel, Katrin; Waldleben, Ana; Zeremski, Vanja; Böttcher, Martin; Brunner-Weinzierl, Monika; Mougiakakos, Dimitrios; Schraven, Burkhart; Jänsch, Lothar; Fischer, Thomas
In: Blood - Washington, DC : American Society of Hematology, Bd. 142 (2023), Heft Supplement 1, Artikel 6340, insges. 2 S.
SLAMF7-signals induce resistance against apoptosis in activated CD8+ T-cells
Orlov, Anastasia; Lingel, Holger; Arra, Aditya; Han, Irina; Brunner-Weinzierl, Monika
In: European journal of immunology - Weinheim : Wiley-VCH, Bd. 53 (2023), Heft Suppl. 2, S. 150, Artikel O 34
Age-related differences in immune reactions to SARS-CoV-2 spike and nucleocapsid antigens
Morhart, Patrick Daniel; Kehl, Sven; Schuh, Wolfgang; Hermes, Katharina; Meltendorf, Stefan; Neubert, Antje; Schneider, Michael; Brunner-Weinzierl, Monika; Schneider, Holm; Lingel, Holger
In: In vivo - Kapandriti, Attiki : IIAR, Bd. 37 (2023), Heft 1, S. 70-78
PD-1 limits differentiation and plasticity of Tc17 cells
Arra, Aditya; Lingel, Holger; Pierau, Mandy; Brunner-Weinzierl, Monika
In: Frontiers in immunology - Lausanne : Frontiers Media, Bd. 14 (2023), Artikel 1104730, insges. 13 S.
PD-1/PD-L1 control of antigen-specifically activated CD4 T-cells of neonates
Majer, Christiane; Lingel, Holger; Arra, Aditya; Heuft, Hans-Gert; Bretschneider, Dirk; Balk, Silke; Vogel, Katrin; Brunner-Weinzierl, Monika
In: International journal of molecular sciences - Basel : Molecular Diversity Preservation International, Bd. 24 (2023), Heft 6, Artikel 5662, insges. 13 S.
An integrated proteome and transcriptome of B cell maturation defines poised activation states of transitional and mature B cells
Salerno, Fiamma; Howden, Andrew J. M.; Matheson, Louise, S.; Gizlenci, Özge; Screen, Michael; Lingel, Holger; Brunner-Weinzierl, Monika; Turner, Martin
In: Nature Communications - [London] : Nature Publishing Group UK, Bd. 14 (2023), Artikel 5116, insges. 18 S.
Bifidobacteria shape antimicrobial T-helper cell responses during infancy and adulthood
Vogel, Katrin; Arra, Aditya; Lingel, Holger; Bretschneider, Dirk; Prätsch, Florian; Schanze, Denny; Zenker, Martin; Balk, Silke; Bruder, Dunja; Geffers, Robert; Hachenberg, Thomas; Arens, Christoph; Brunner-Weinzierl, Monika
In: Nature Communications - [London] : Nature Publishing Group UK, Bd. 14 (2023), Artikel 5943, insges. 13 S.
Das Bifidobakterium infantis als Wächter des Immunsystems
Vogel, Katrin; Brunner-Weinzierl, Monika
In: Ärzteblatt Sachsen-Anhalt - Magdeburg : Ärztekammer Sachsen-Anhalt, Bd. 34 (2023), Heft 12, S. 28-29
2022
Analysis of exhausted T cells, systemically enhanced cytokine levels ex vivo and machine learning facilitated search for ageing-related biomarkers
Beyer, Christian; Jamaludeen, Noor; Vogel, Katrin; Pierau, Mandy; Lingel, Holger; Meltendorf, Stefan; Spiliopoulou, Myra; Brunner-Weinzierl, Monika
In: Das Gesundheitswesen - Stuttgart [u.a.] : Thieme, Bd. 84 (2022), Heft 8/9, S. 846
T cell responses after immune checkpoint blockade differ between children, teenagers and adults
Aign, Clara; Arra, Aditya; Vosiková, Tereza; Vorwerk, Ulrich; Heuft, Hans-Gert; Vogel, Katrin; Lingel, Holger; Brunner-Weinzierl, Monika
In: European journal of immunology - Weinheim : Wiley-VCH, Bd. 52 (2022), Heft Suppl. 1, S. 275, Artikel P 140
Staphylococcus aureus and Bifidobacterium longum are well recognized by T-cells with opposite results
Vogel, Katrin; Arra, Aditya; Lingel, Holger; Bretschneider, Dirk; Prätsch, Florian; Schanze, Denny; Zenker, Martin; Bruder, Dunja; Hachenberg, Thomas; Arens, Christoph; Brunner-Weinzierl, Monika
In: European journal of immunology - Weinheim : Wiley-VCH, Bd. 52 (2022), Heft Suppl. 1, S. 265, Artikel P 129
Unique lasting effects on immune composition and autoantibody prevalence after mild SARS-CoV-2 infections
Lingel, Holger; Meltendorf, Stefan; Billing, Ulrike; Thurm, Christoph; Vogel, Katrin; Majer, Christiane; Prätsch, Florian; Roggenbuck, Dirk; Heuft, Hans-Gert; Hachenberg, Thomas; Feist, Eugen; Reinhold, Dirk; Brunner-Weinzierl, Monika
In: European journal of immunology - Weinheim : Wiley-VCH, Bd. 52 (2022), Heft Suppl. 1, S. 173-174, Artikel P 028
PD-1 suppresses differentiation and plasticity of IL-17 producing CD8+ T-cells (Tc17 cells)
Arra, Aditya; Pierau, Mandy; Lingel, Holger; Brunner-Weinzierl, Monika
In: European journal of immunology - Weinheim : Wiley-VCH, Bd. 52 (2022), Heft Suppl. 1, S. 330-331, Artikel P 203
Age dependence of T cell immune responses against bacteria and fungi in cystic fibrosis patients
Paszkier, Michelle; Vogel, Katrin; Pierau, Mandy; Meltendorf, Stefan; Vosiková, Tereza; Heuft, Hans-Gert; Gleißner, Michael; Bruder, Dunja; Arra, Aditya; Vorwerk, Ulrich; Schreiber, Jens; Brunner-Weinzierl, Monika
In: European journal of immunology - Weinheim : Wiley-VCH, Bd. 52 (2022), Heft Suppl. 1, S. 277, Artikel P 142
SLAMF7 (CD319) is a co-stimulatory molecule on CD4+ T-cells and regulated by CTLA-4 and TGFβ
Han, Irina; Arra, Aditya; Lingel, Holger; Brunner-Weinzierl, Monika
In: European journal of immunology - Weinheim : Wiley-VCH, Bd. 52 (2022), Heft Suppl. 1, S. 331-332, Artikel P 205
Developmental bias of newly synthesized proteins in Candida albicans-activated human CD4+ T-cells
Balk, Silke; Pierau, Mandy; Vogel, Katrin; Reinking, Janne; Vosiková, Tereza; Cakir, Eda; Bretschneider, Dirk; Jänsch, Lothar; Vorwerk, Ulrich; Heuft, Hans-Gert; Hütt, Marc-Thorsten; Arra, Aditya; Brunner-Weinzierl, Monika
In: European journal of immunology - Weinheim : Wiley-VCH, Bd. 52 (2022), Heft Suppl. 1, S. 273-274, Artikel P 138
Differential trafficking of ligands trogocytosed via CD28 versus CTLA4 promotes collective cellular control of co-stimulation
Zenke, Simon; Sica, Mauricio P.; Steinberg, Florian; Braun, Julia; Zink, Alicia; Gavrilov, Alina; Hilger, Alexander; Arra, Aditya; Brunner-Weinzierl, Monika; Elling, Roland; Beyersdorf, Niklas; Lämmermann, Tim; Smulski, Cristian R.; Rohr, Jan
In: Nature Communications - [London] : Springer Nature, Bd. 13 (2022), Artikel 6459, insges. 18 S.
Assessment of immune status using inexpensive cytokines - a literature review and learning approaches
Jamaludeen, Noor; Lehmann, Juliane; Beyer, Christian; Vogel, Katrin; Pierau, Mandy; Brunner-Weinzierl, Monika; Spiliopoulou, Myra
In: Sensors - Basel : MDPI, Bd. 22 (2022), Heft 24, Artikel 9785, insges. 26 S.
IL-13 determines specific IgE responses and SARS-CoV-2 immunity after mild COVID-19 and novel mRNA vaccination
Meltendorf, Stefan; Vogel, Katrin; Thurm, Christoph; Prätsch, Florian; Reinhold, Annegret; Färber, Jacqueline; Heuft, Hans-Gert; Kaasch, Achim; Hachenberg, Thomas; Weinzierl, Stefan; Schraven, Burkhart; Reinhold, Dirk; Brunner-Weinzierl, Monika; Lingel, Holger
In: European journal of immunology - Weinheim : Wiley-VCH, Bd. 52 (2022), Heft 12, S. 1972-1979
2021
Opposing effects of Bifidobacterium longum and Staphylococcus aureus after recognition by paediatric T cells
Vogel, Katrin; Arra, Aditya; Lingel, Holger; Bretschneider, Dirk; Prätsch, Florian; Zenker, Martin; Freund, Christian; Bruder, Dunja; Hachenberg, Thomas; Arens, Christoph; Brunner-Weinzierl, Monika
In: European journal of immunology - Weinheim : Wiley-VCH, Bd. 51 (2021), Heft Suppl. 1, S. 350, Artikel P-0880
Immune-checkpoint blockade of CTLA-4 (CD152) in antigen-specific human T-cell responses differs profoundly between neonates, children, and adults
Arra, Aditya; Pech, Maximilian; Fu, Hang; Lingel, Holger; Braun, Franziska; Beyer, Christian; Spiliopoulou, Myra; Bröker, Barbara; Lampe, Karen; Arens, Christoph; Vogel, Katrin; Pierau, Mandy; Brunner-Weinzierl, Monika
In: OncoImmunology - Abingdon : Taylor & Franics, Bd. 10 (2021), Heft 1, Artikel e1938475, insges. 12 S.
Plasma membrane Ca2+ ATPase 1 (PMCA1) but not PMCA4 is critical for B-cell development and Ca2+ homeostasis in mice
Korthals, Mark; Tech, Laura; Langnaese, Kristina; Gottfried, Anna; Hradsky, Johannes; Thomas, Ulrich; Zenclussen, Ana Claudia; Brunner-Weinzierl, Monika; Tedford, Kerry; Fischer, Klaus-Dieter
In: European journal of immunology - Weinheim : Wiley-VCH, Bd. 51 (2021), Heft 3, S. 594-602
Preventing atopic diseases during childhood - early exposure matters
Pierau, Mandy; Arra, Aditya; Brunner-Weinzierl, Monika
In: Frontiers in immunology - Lausanne : Frontiers Media, Bd. 12 (2021), Artikel 617731, insges. 14 S.
Potential of point-of-care and at-home assessment of immune status via rapid cytokine detection and questionnaire-based anamnesis
Jamaludeen, Noor; Beyer, Christian; Billing, Ulrike; Vogel, Katrin; Brunner-Weinzierl, Monika; Spiliopoulou, Myra
In: Sensors - Basel : MDPI, Bd. 21 (2021), Heft 15, Artikel 4960, insges. 33 S.
Unique autoantibody prevalence in long-term recovered SARS-CoV-2-infected individuals
Lingel, Holger; Meltendorf, Stefan; Billing, Ulrike; Thurm, Christoph; Vogel, Katrin; Majer, Christiane; Prätsch, Florian; Roggenbuck, Dirk; Heuft, Hans-Gert; Hachenberg, Thomas; Feist, Eugen; Reinhold, Dirk; Brunner-Weinzierl, Monika
In: Journal of autoimmunity - London : Academic Press, Bd. 122 (2021), Artikel 102682, insges. 8 S.
The regulation of the expression of PMCA isoforms by neuroplastin has an impact on the calcium clearance in cultured hippocampal neurons
Junge, Lennart; Brunner-Weinzierl, Monika; Roßner, Steffen
In: Magdeburg: Otto-von-Guericke-Universität Magdeburg, Dissertation Universität Magdeburg 2021, vi, 55 Blätter
2020
CTLA-4-competent conventional T-cells back up regulatory T-cells to restrain memory T-helper type 2 cell responses. Letter to the editor
Pierau, Mandy; Lingel, Holger; Vogel, Katrin; Arra, Aditya; Brunner-Weinzierl, Monika
In: Allergy - Oxford : Wiley, Bd. 75 (2020), Heft 3, S. 684-687
Cell survival failure in effector T cells from patients with systemic lupus erythematosus following insufficient upregulation of coldshock Ybox binding protein 1
Meltendorf, Stefan; Fu, Hang; Pierau, Mandy; Lindquist, Jonathan A.; Finzel, Stephanie; Mertens, Peter Rene; Gieseler-Halbach, Steffi; Ambach, Andreas; Thomas, Ulrich; Lingel, Holger; Voll, Reinhard; Brunner-Weinzierl, Monika
In: Arthritis & rheumatology - Hoboken, NJ : Wiley, Bd. 72 (2020), Heft 10, S. 1721-1733
Children from the age of three show a developmental switch in T-cell differentiation
Knolle, Julienne; Pierau, Mandy; Hebel, Katrin; Lampe, Karen; Jorch, Gerhard; Kropf, Siegfried; Arens, Christoph; Brunner-Weinzierl, Monika
In: Frontiers in immunology - Lausanne : Frontiers Media - Vol. 11.2020, Art.-Nr. 1640, insgesamt 12 Seiten
YB-1 interferes with TNFα-TNFR binding and modulates progranulin-mediated inhibition of TNFα signaling
Hessman, Christopher L.; Hildebrandt, Josephine; Shah, Aneri; Brandt, Sabine; Bock, Antonia; Frye, Björn Christian; Raffetseder, Ute; Geffers, Robert; Brunner-Weinzierl, Monika; Isermann, Berend; Mertens, Peter Rene; Lindquist, Jonathan A.
In: International journal of molecular sciences - Basel : Molecular Diversity Preservation International - Vol. 21.2020, 19, Art.-Nr. 7076, insgesamt 17 Seiten
2019
IFN-γ is a therapeutic target in paraneoplastic cerebellar degeneration
Yshii, Lidia; Pignolet, Béatrice; Mauré, Emilie; Pierau, Mandy; Brunner-Weinzierl, Monika; Hartley, Oliver; Bauer, Jan; Liblau, Roland
In: JCI insight - Ann Arbor, Michigan : JCI Insight - Bd. 4.2019, 7, Art.-Nr. e127001, insges. 12 S.
Aktuelle Entwicklungen in der Allergieprävention
Brunner-Weinzierl, Monika; Kopp, Matthias
In: Consilium - Wien : Ärztekammer für Niederösterreich, Körperschaft Öffentlichen Rechts, Bd. 74 (2019), Heft 11, S. 26-31
CTLA-4 (CD152) - a versatile receptor for immune-based therapy
Lingel, Holger; Brunner-Weinzierl, Monika
In: Seminars in immunology - London : Academic Press - Bd.42.2019, Art.-Nr. 101298
2018
Paradigmenwechsel in der Allergieprävention
Brunner-Weinzierl, Monika; Kopp, Matthias
In: Monatsschrift Kinderheilkunde - Berlin : Springer, Bd. 166 (2018), Heft 8, S. 708-713
Developmental induction of human T-cell responses against Candida albicans and Aspergillus fumigatus
Vogel, Katrin; Pierau, Mandy; Arra, Aditya; Lampe, Karen; Schlüter, Dirk; Arens, Christoph; Brunner-Weinzierl, Monika
In: Scientific reports - [London] : Macmillan Publishers Limited, part of Springer Nature - Bd. 8.2018, Art.-Nr. 16904, insges. 14 S.
CTLA-4 and PD-1 control of T-cell motility and migration - implications for tumor immunotherapy
Brunner-Weinzierl, Monika; Rudd, Christopher E.
In: Frontiers in immunology - Lausanne : Frontiers Media - Bd. 9.2018, Art.-Nr. 2737, insges. 8 S.
2017
Bacteria-specific CD4+T-cell responses of neonates, infants and adults show age-dependent characteristics
Vogel, Katrin; Braun, Franziska; Pierau, Mandy; Lampe, Karen; Jorch, Gerhard; Schlüter, Dirk; Arens, Christoph; Brunner-Weinzierl, Monika
In: European journal of immunology - Weinheim : Wiley - Bd. 47.2017, Suppl. 2, P357, S. 264
CTLA-4 mediated effects on STATs regulate differentiation and plasticity of Tc17 cells
Arra, Aditya; Lingel, Holger; Kuropka, Benno; Fischer, Thomas; Freund, Christian; Pierau, Mandy; Brunner-Weinzierl, Monika
In: European journal of immunology - Weinheim : Wiley VCH - Bd. 47.2017, Suppl. 2, P395, S. 277
Eingeschränkte Immunabwehr gegen bekapselte Bakterien
Brunner-Weinzierl, Monika
In: Fetoneonatale Infektiologie , 1. Auflage - Stuttgart : Georg Thieme Verlag . - 2017, S. 36
Angeborenes Immunsystem von Fötus, Neonaten und Kleinkind
Brunner-Weinzierl, Monika
In: Fetoneonatale Infektiologie , 1. Auflage - Stuttgart : Georg Thieme Verlag . - 2017, S. 23-27
Hygienehypothese
Brunner-Weinzierl, Monika
In: Fetoneonatale Infektiologie , 1. Auflage - Stuttgart : Georg Thieme Verlag . - 2017, S. 34-35
Adaptives Immunsystem
Brunner-Weinzierl, Monika
In: Fetoneonatale Infektiologie , 1. Auflage - Stuttgart : Georg Thieme Verlag . - 2017, S. 27-34
CTLA-4-mediated posttranslational modifications direct cytotoxic T-lymphocyte differentiation
Lingel, Holger; Wissing, Josef; Arra, Aditya; Schanze, Denny; Lienenklaus, Stefan; Klawonn, Frank; Pierau, Mandy; Zenker, Martin; Jänsch, Lothar; Brunner-Weinzierl, Monika
In: Cell death and differentiation - Houndmills, Basingstoke : Nature Publishing Group, Bd. 24 (2017), Heft 10, S. 1739-1749
RSK-mediated nuclear accumulation of the cold-shock Y-box protein-1 controls proliferation of T cells and T-ALL blasts
Gieseler-Halbach, Steffi; Meltendorf, Stefan; Pierau, Mandy; Weinert, Sönke; Heidel, Florian; Fischer, Thomas; Handschuh, Juliane; Braun-Dullaeus, Ruediger C.; Schrappe, Martin; Lindquist, Jonathan A.; Mertens, Peter Rene; Thomas, Ulrich; Brunner-Weinzierl, Monika
In: Cell death and differentiation - Houndmills, Basingstoke : Nature Publishing Group, Bd. 24 (2017), Heft 2, S. 371-383
The differentiation and plasticity of Tc17 cells are regulated by CTLA-4-mediated effects on STATs
Arra, Aditya; Lingel, Holger; Kuropka, Benno; Pick, Jonas; Schnöder, Tina; Fischer, Thomas; Freund, Christian; Pierau, Mandy; Brunner-Weinzierl, Monika
In: OncoImmunology - Abingdon : Taylor & Franics - Bd. 6.2017, 2, Art.-Nr. e1273300, insges. 5 S.
Activated protein C protects from GvHD via PAR2/PAR3 signalling in regulatory T-cells
Ranjan, Satish; Goihl, Alexander; Kohli, Shrey; Gadi, Ihsan; Pierau, Mandy; Shahzad Hussain, Khurrum; Gupta, Dheerendra; Bock, Fabian; Wang, Hongjie; Shaikh, Haroon; Kähne, Thilo; Reinhold, Dirk; Bank, Ute; Zenclussen, Ana Claudia; Niemz, Jana; Schnöder, Tina; Brunner-Weinzierl, Monika; Fischer, Thomas; Kalinski, Thomas; Schraven, Burkhart; Luft, Thomas; Hühn, Jochen; Naumann, Michael; Heidel, Florian; Isermann, Berend
In: Nature Communications - [London] : Nature Publishing Group UK - 8(2017) Artikel-Nummer 311, 16 Seiten
Inflammatory cell infiltration and resolution of kidney inflammation is orchestrated by the cold-shock protein Y-box binding protein-1
Bernhardt, Anja; Fehr, Alexander; Brandt, Sabine; Jerchel, Saskia; Ballhause, Tobias M.; Philipsen, Lars; Stolze, Saskia; Geffers, Robert; Weng, Honglei; Fischer, Klaus-Dieter; Isermann, Berend; Brunner-Weinzierl, Monika; Batra, Arvind; Siegmund, Britta; Zhu, Cheng; Lindquist, Jonathan A.; Mertens, Peter Rene
In: Kidney international - New York, NY : Elsevier, Bd. 92 (2017), Heft 5, S. 1157-1177
CTLA-4 induced signal transduction in regulating differentiation and plasticity of Tc17 cells
Arra, Aditya; Brunner-Weinzierl, Monika
In: Magdeburg, Dissertation Otto-von-Guericke-Universität Magdeburg, Fakultät für Naturwissenschaften 2017, x, 84 Blätter [Literaturverzeichnis: Blatt 63-79][Literaturverzeichnis: Blatt 63-79]
2016
Intrinsic- and extrinsic- mediated CTLA-4-signals shape the TH2 response - implications for allergic disorders
Pierau, Mandy; Brunner-Weinzierl, Monika
In: European journal of immunology - Weinheim : Wiley VCH - Bd. 46.2016, Suppl. 1, Abs. 3557, Seite 1053
CD4+ T cells from human neonates and infants respond variously against antigens of Staphylococcus aureus, but not against Bifidobacter longum ssp. infantis
Brunner-Weinzierl, Monika; Pierau, Mandy; Schlüter, Dirk; Lampe, Karen; Arens, Christoph; Jorch, Gerhard; Vogel, Katrin
In: The journal of immunology - Rockville, Md. : American Association of Immunologists - Bd. 196.2016, 1 Suppl., Abs. 66.24, insges. 1 S.
Implikationen für allergische Erkrankungen - CTLA-4-Signale beeinflussen nachhaltig TH2-Immunantworten
Pierau, Mandy; Brunner-Weinzierl, Monika
In: Allergologie - München-Deisenhofen [i.e.] Deisenhofen : Dustri-Verl. Feistle, Bd. 39 (2016), Heft 5, S. 225
Plasticity along with differentiation of Tc17 cells is controlled by CTLA-4 (CD152)
Brunner-Weinzierl, Monika; Lingel, Holger; Pick, Jonas; Huber, Magdalena; Pierau, Mandy; Arra, Aditya
In: The journal of immunology - Rockville, Md. : American Association of Immunologists - Bd. 196.2016, 1 Suppl., Abs. 133.15, insges. 1 S.
CTLA-4-targeted proteins in differentiating CD8+ T lymphocytes
Brunner-Weinzierl, Monika; Wissing, Josef; Arra, Aditya; Pierau, Mandy; Klawonn, Frank; Jänsch, Lothar; Lingel, Holger
In: The journal of immunology - Rockville, Md. : American Association of Immunologists - Bd. 196.2016, 1 Suppl., Abs. 72.19, insges. 1 S.
Charakterisierung infektionsspezifischer T-Zell-Antworten bei Neugeborenen und Kleinkindern
Vogel, Katrin; Pierau, Mandy; Lampe, Karen; Jorch, Gerhard; Schlüter, Dirk; Arens, Christoph; Brunner-Weinzierl, Monika
In: Allergologie - München-Deisenhofen [i.e.] Deisenhofen : Dustri-Verl. Feistle, Bd. 39 (2016), Heft 5, S. 227-228
Early changes in the metabolic profile of activated CD8+ T cells
Cammann, Clemens; Rath, Alexander; Reichl, Udo; Lingel, Holger; Brunner-Weinzierl, Monika; Simeoni, Luca; Schraven, Burkhart; Lindquist, Jonathan A.
In: BMC cell biology - London : BioMed Central - Bd. 17.2016, Art.-Nr. 28, insges. 11 S.
T cells of infants are mature, but hyporeactive due to limited Ca2+ influx
Schmiedeberg, Kristin; Krause, Hardy; Röhl, Friedrich-Wilhelm; Hartig, Roland; Jorch, Gerhard; Brunner-Weinzierl, Monika
In: PLOS ONE - San Francisco, California, US : PLOS - Bd. 11.2016, 11, Art.-Nr. e0166633, insges. 27 S.
CTLA4 blockade elicits paraneoplastic neurological disease in a mouse model
Yshii, Lidia M.; Gebauer, Christina M.; Pignolet, Béatrice; Mauré, Emilie; Quériault, Clémence; Pierau, Mandy; Saito, Hiromitsu; Suzuki, Noboru; Brunner-Weinzierl, Monika; Bauer, Jan; Liblau, Roland
In: Brain - Oxford : Oxford Univ. Press, Bd. 139 (2016), Heft 11, S. 2923-2934
2014
CTLA-4 (CD152) enhances the Tc17 differentiation program
Pick, Jonas; Arra, Aditya; Lingel, Holger; Hegel, J. Kolja; Huber, Magdalena; Nishanth, Gopala; Jorch, Gerhard; Fischer, Klaus-Dieter; Schlüter, Dirk; Tedford, Kerry; Brunner-Weinzierl, Monika
In: European journal of immunology - Weinheim : Wiley-VCH, Bd. 44 (2014), Heft 7, S. 2139-2152
Clinically relevant doses of FLT3-kinase inhibitors Quizartinib and Midostaurin do not impair T-cell reactivity and function
Wolleschak, Denise; Mack, Thomas S.; Perner, Florian; Frey, Stephanie; Schnöder, Tina; Wagner, Marie-Christine; Höding, Christine; Pils, Marina C.; Parkner, Andreas; Kliche, Stefanie; Schraven, Burkhart; Hebel, Katrin; Brunner-Weinzierl, Monika; Ranjan, Satish; Isermann, Berend; Lipka, Daniel; Fischer, Thomas; Heidel, Florian
In: Haematologica - Pavia : Ferrata Storti Foundation - Bd. 99.2014, 6, S. e90-e93
CD4+ T cells from human neonates and infants are poised spontaneously to run a nonclassical IL-4 program
Hebel, Katrin; Weinert, Soenke; Kuropka, Benno; Knolle, Julienne; Kosak, Bernhard; Jorch, Gerhard; Arens, Christoph; Krause, Eberhard; Braun-Dullaeus, Ruediger C.; Brunner-Weinzierl, Monika
In: The journal of immunology - Bethesda, Md : Soc, Bd. 192 (2014), Heft 11, S. 5160-5170
CTLA-4 is expressed by activated mouse NK cells and inhibits NK cell IFN-[gamma] production in response to mature dendritic cells
Stojanovic, Ana; Fiegler, Nathalie; Brunner-Weinzierl, Monika; Cerwenka, Adelheid
In: The journal of immunology - Bethesda, Md. : Soc., Bd. 192 (2014), Heft 9, S. 4184-4191
Autoimmune pancreatitis in MRL/Mp mice is a T cell-mediated disease responsive to cyclosporine A and rapamycin treatment
Schwaiger, Theresa; Brandt, Cindy; Fitzner, Brit; Zaatreh, Sarah; Kraatz, Franziska; Dummer, Annegret; Nizze, Horst; Evert, Matthias; Bröker, Barbara; Brunner-Weinzierl, Monika; Wartmann, Thomas; Salem, Tareq; Lerch, Markus M.; Jaster, Robert; Mayerle, Julia
In: Gut - London : BMJ Publishing Group, Bd. 63 (2014), Heft 3, S. 494-505
2013
Impact of the CTLA-4/CD28 axis on the processes of joint inflammation in rheumatoid arthritis
Körmendy, Dezsö; Hoff, Holger; Hoff, Paula; Bröker, Barbara; Burmester, Gerd-Rüdiger; Brunner-Weinzierl, Monika
In: Arthritis & rheumatism - Hoboken, NJ : Wiley-Blackwell, Bd. 65 (2013), Heft 1, S. 81-87
PAG/Cbp suppression reveals a contribution of CTLA-4 to setting the activation threshold in T cells
Smida, Michal; Cammann, Clemens; Gurbiel, Slavyana; Kerstin, Nadja; Lingel, Holger; Lindquist, Sabine; Simeoni, Luca; Brunner-Weinzierl, Monika; Suchanek, Miloslav; Schraven, Burkhart; Lindquist, Jonathan A.
In: Cell communication and signaling - London : Biomed Central - Bd. 11.2013, Art.-Nr. 28, insges. 13 S.
Acute psychological stress increases peripheral blood CD3+CD56+ natural killer T cells in healthy men: possible implications for the development and treatment of allergic and autoimmune disorders
Atanackovic, Djordje; Nowottne, Ulrike; Freier, Eva; Weber, Cora Stefanie; Meyer, Sabrina; Bartels, Katrin; Hildebrandt, York; Cao, Yanran; Kröger, Nicolaus; Brunner-Weinzierl, Monika; Bokemeyer, Carsten; Deter, Hans-Christian
In: Stress - London : Informa Healthcare, Bd. 16 (2013), Heft 4, S. 421-428
Das neonatale Immunsystem - Modulation durch regulatorische T-Zellen und CTLA-4 (CD152) : modulation by regulatory T-cells and CTLA-4 - The neonatal immune system
Hebel, Katrin; Pierau, Mandy; Lingel, Holger; Steiner, Michael; Krause, Hardy; Jorch, Gerhard; Brunner-Weinzierl, Monika
In: Laboratoriumsmedizin - Berlin [u.a.] : de Gruyter, Bd. 37 (2013), Heft 3, S. 123-129
Immune privilege as an intrinsic CNS property - astrocytes protect the CNS against T-cell-mediated neuroinflammation
Gimsa, Ulrike; Mitchison, Avrion; Brunner-Weinzierl, Monika
In: Mediators of inflammation - Sylvania, Ohio : Hindawi Publishing Corp. - 2013, Article ID 320519, insges. 11 S.
Untersuchung des Einflusses der Histon-H3K9-Acetylierung auf die Prognose beim Neuroblastom
Dietl, Johanna; Brunner-Weinzierl, Monika
In: Magdeburg, Univ., Med. Fak., Diss., 2013, XVIII, 53 Bl
2012
Migration of Th1 lymphocytes is regulated by CD152 (CTLA-4)-mediated signaling via PI3 kinase-dependent Akt activation
Knieke, Karin; Lingel, Holger; Chamaon, Kathrin; Brunner-Weinzierl, Monika
In: PLOS ONE - San Francisco, California, US : PLOS - Bd. 7.2012, 3, Artikel-Nr. e31391, insges. 9 S.
Pro-inflammatory effector Th cells transmigrate through anti-inflammatory environments into the murine fetus
Wienecke, Janine; Hebel, Katrin; Hegel, Kolja J.; Pierau, Mandy; Brune, Thomas; Reinhold, Dirk; Pethe, Annette; Brunner-Weinzierl, Monika
In: Placenta - Amsterdam [u.a.] : Elsevier, Bd. 33 (2012), Heft 1, S. 39-46
Activation of the Hippo pathway by CTLA-4 regulates the expression of Blimp-1 in the CD8+ T cell
Thaventhiran, James E. D.; Hoffmann, Anja; Magiera, Lukasz; Roche, Maike de la; Lingel, Holger; Brunner-Weinzierl, Monika; Fearon, Douglas T.
In: Proceedings of the National Academy of Sciences of the United States of America - Washington, DC : National Acad. of Sciences - Bd. 109.2012, 33, S. E2223-E2229
2011
Einfluss von CD152-Signalen auf das Migrationsverhalten von T H 1-Lymphozyten
Knieke, Karin; Brunner-Weinzierl, Monika C.
In: Magdeburg, Univ., Fak. für Naturwiss., Diss., 2011, 114 Bl.
IL-1[beta] and TGF-[beta] act antagonistically in induction and differentially in propagation of human proinflammatory precursor CD4+ T cells
Hebel, Katrin; Rudolph, Marion; Kosak, Bernhard; Chang, Hyun-Dong; Butzmann, Jana; Brunner-Weinzierl, Monika
In: The journal of immunology - Rockville, Md. : American Association of Immunologists, Bd. 187 (2011), Heft 11, S. 5627-5635
Blockade of CTLA-4 decreases the generation of multifunctional memory CD4+ T Cells in vivo
Rudolph, Marion; Hebel, Katrin; Miyamura, Yoshinori; Maverakis, Emanual; Brunner-Weinzierl, Monika
In: The journal of immunology - Rockville, Md. : American Association of Immunologists, Bd. 186 (2011), Heft 10, S. 5580-5589
CTLA-4 (CD152) blockade does not cause a pro-inflammatory cytokine profile in regulatory T cells
Kolar, Paula; Hoff, Holger; Maschmeyer, Patrick; Burmester, Gerd-Rüdiger; Brunner-Weinzierl, Monika
In: Clinical and experimental rheumatology - Pisa : Pacini, Bd. 29 (2011), Heft 2, S. 254-260
Glycogen synthase kinase-3[beta] is a crucial mediator of signal-induced RelB degradation
Neumann, Manfred; Klar, S.; Wilisch-Neumann, Annette; Hollenbach, Eike; Kavuri, Shyam; Leverkus, Martin; Kandolf, Reinhard; Brunner-Weinzierl, Monika; Klingel, Karin
In: Oncogene - New York, NY : Springer Nature, Bd. 30 (2011), Heft 21, S. 2485-2492
2010
CTLA-4 (CD152) inhibits T cell function by activating the ubiquitin ligase Itch
Hoff, Holger; Kolar, Paula; Ambach, Andreas; Radbruch, Andreas; Brunner-Weinzierl, Monika
In: Molecular immunology - Amsterdam [u.a.] : Elsevier, Bd. 47 (2010), Heft 10, S. 1875-1881
Decrease of CD4+FOXP3+ T regulatory cells in the peripheral blood of human subjects undergoing a mental stressor
Freier, Eva; Weber, Cora Stefanie; Nowottne, Ulrike; Horn, Christiane; Bartels, Katrin; Meyer, Sabrina; Hildebrandt, York; Luetkens, Tim; Cao, Yanran; Pabst, Caroline; Muzzulini, Julia; Schnee, Benjamin; Brunner-Weinzierl, Monika; Marangolo, Maurizio; Bokemeyer, Carsten; Deter, Hans-Christian; Atanackovic, Djordje
In: Psychoneuroendocrinology - Oxford [u.a.] : Elsevier, Bd. 35 (2010), Heft 5, S. 663-673, insges. 11 S. [Im Titel sind die Pluszeichen jeweils hochgestellt]
Female-biased incidence of experimental autoimmune encephalomyelitis reflects sexually dimorphic expression of surface CTLA-4 (CD152) on T lymphocytes
Luna, Rosa María Licón; Körmendy, Dezsö; Brunner-Weinzierl, Monika
In: Gender medicine - Hillsborough, NJ : Excerpta Medica, Bd. 7 (2010), Heft 4, S. 296-308
2009
Surface CD152 (CTLA-4) expression and signaling dictates longevity of CD28null T cells
Hoff, Holger; Knieke, Karin; Cabail, Zulema; Hirseland, Heike; Vratsanos, George; Burmester, Gerd-Rüdiger; Jorch, Gerhard; Nadler, Steven G.; Bröker, Barbara; Hebel, Katrin; Brunner-Weinzierl, Monika
In: The journal of immunology - Rockville, Md. : American Association of Immunologists, Bd. 182 (2009), Heft 9, S. 5342-5351
CD152 (CTLA-4) determines CD4 T cell migration in vitro and in vivo
Knieke, Karin; Hoff, Holger; Maszyna, Frank; Kolar, Paula; Schrage, Arnhild; Hamann, Alf; Debes, Gudrun F.; Brunner-Weinzierl, Monika
In: PLOS ONE - San Francisco, California, US : PLOS - Bd. 4.2009, 5, Art. e5702, insges. 11 S.
CTLA-4 (CD152) controls homeostasis and suppressive capacity of regulatory T cells in mice
Kolar, Paula; Knieke, Karin; Hegel, J. Kolja E.; Quandt, Dagmar; Burmester, Gerd-Rüdiger; Hoff, Holger; Brunner-Weinzierl, Monika
In: Arthritis & rheumatism - Hoboken, NJ : Wiley-Blackwell, Bd. 60 (2009), Heft 1, S. 123-132
CD152 (CTLA-4) regulates effector functions of CD8+ T lymphocytes by repressing Eomesodermin
Hegel, Johannes K.; Knieke, Karin; Kolar, Paula; Reiner, Steven L.; Brunner-Weinzierl, Monika
In: European journal of immunology - Weinheim : Wiley, Bd. 39 (2009), Heft 3, S. 883-893
2008
CTLA-4 (CD152) controls homeostasis and suppressive capacity of regulatory T cells in mice
Kolar, Paula; Knieke, Karin; Hegel, J. Kolja E.; Quandt, Dagmar; Burmester, Gerd-R.; Hoff, Holger; Brunner-Weinzierl, Monika
In: Arthritis & rheumatism - Hoboken, NJ : Wiley-Blackwell, Bd. 60 (2008), Heft 1, S. 123-32
2007
High IFN- Production of Individual CD8 T Lymphocytes Is Controlled by CD152 (CTLA-4)
Pandiyan, Pushpa; Hegel, Kolja E.; Krueger, Manuela; Quandt, Dagmar; Brunner-Weinzierl, Monika C.
In: The journal of immunology - Rockville, Md. : American Association of Immunologists, Bd. 178 (2007), Heft 4, S. 2132-2140
A new role of CTLA-4 on B cells in thymus-dependent immune responses in vivo
Quandt, Dagmar; Hoff, Holger; Rudolph, Marion; Fillatreau, Simon; Brunner-Weinzierl, Monika
In: The journal of immunology - Rockville, Md. : American Association of Immunologists, Bd. 179 (2007), Heft 11, S. 7316-7324
A new role of CTLA-4 on B cells in thymus-dependent immune responses in vivo
Quandt, Dagmar; Hoff, Holger; Rudolph, Marion; Fillatreau, Simon; Brunner-Weinzierl, Monika
In: The journal of immunology - Rockville, Md. : American Association of Immunologists, Bd. 179 (2007), Heft 11, S. 7316-7324
2006
CD25 regulatory T cells determine secondary but not primary remission in EAE: impact on long-term disease progression
Gärtner, Dagmar; Hoff, Holger; Gimsa, Ulrike; Burmester, Gerd-R.; Brunner-Weinzierl, Monika C.
In: Journal of neuroimmunology . - Amsterdam : Elsevier, Bd. 172.2006, 1, S. 73-84