Publikationen
2025
Two degrees of freedom control of a multistage power-to-methanol reactor
Keßler, Tobias; Plate, Christoph; Behrens, Jessica; Martensen, Carl J.; Leipold, Johannes; Kaps, Lothar; Seidel-Morgenstern, Andreas; Sager, Sebastian; Kienle, Achim
In: Computers & chemical engineering - Amsterdam [u.a.] : Elsevier Science, Bd. 192 (2025), Artikel 108893, insges. 9 S.
Optimal experiments for hybrid modeling of methanol synthesis kinetics
Kaps, Lothar; Leipold, Johannes; Plate, Christoph; Martensen, Carl Julius; Kortuz, Wieland; Seidel-Morgenstern, Andreas; Kienle, Achim; Sager, Sebastian
In: Computers & chemical engineering - Amsterdam [u.a.] : Elsevier Science, Bd. 204 (2025), Artikel 109387, insges. 13 S.
Surrogate modeling for control of microbial biopolymer production process
Dürr, Robert; Otto, Eric; Kok, Rudolph L.; Duvigneau, Stefanie; Kienle, Achim; Bück, Andreas
In: IFAC-PapersOnLine / Internationale Förderung für Automatische Lenkung - Frankfurt : Elsevier, Bd. 59 (2025), Heft 1, S. 169-174
Kinetic modeling of the methanol-assisted autocatalytic methanol synthesis on Cu/ZnO/Al2O3
Kortuz, Wieland; Leipold, Johannes; Kienle, Achim; Seidel-Morgenstern, Andreas
In: The chemical engineering journal - Amsterdam : Elsevier, Bd. 518 (2025), Artikel 164505, insges. 10 S.
Nonlinear behavior of methanol synthesis through CO2-hydrogenation
Leipold, Johannes; Kienle, Achim
In: The chemical engineering journal - Amsterdam : Elsevier, Bd. 522 (2025), Artikel 167176, insges. 13 S.
Optimization of methanol synthesis under forced periodic operation in isothermal fixed-bed reactors
Leipold, Johannes; Nikolic, Daliborka; Seidel-Morgenstern, Andreas; Kienle, Achim
In: Computers & chemical engineering - Amsterdam [u.a.] : Elsevier Science, Bd. 196 (2025), Artikel 109040
Surrogate modeling of microbial PHA-biopolymer synthesis
Dürr, Robert; Otto, Eric; Kok, Rudolph; Hempfling, Stefan; Duvigneau, Stefanie; Kienle, Achim; Bück, Andreas
In: Industrial & engineering chemistry research - Columbus, Ohio : American Chemical Society, Bd. 64 (2025), Heft 38, S. 18640-18655
Estimation of PHA concentrations from cell density data in Cupriavidus necator
Kranert, Lena; Kok, Rudolph; Neumann, Anne-Sophie; Kienle, Achim; Duvigneau, Stefanie
In: Applied microbiology and biotechnology - Berlin : Springer, Bd. 109 (2025), Artikel 11, insges. 11 S.
Computer-aided optimization of resource-efficient and flexible power-to-syngas processes
Maggi, Andrea; Janiga, Gábor; Sundmacher, Kai; Kienle, Achim
In: Magdeburg: Universitätsbibliothek, Dissertation Otto-von-Guericke-Universität Magdeburg, Fakultät für Verfahrens- und Systemtechnik 2025, 1 Online-Ressource (XI, 208 Blätter, 12,95 MB) [Literaturverzeichnis: Blatt 186-200]
Efficient simulation and optimization of simulated moving bed chromatography processes
Pishkari, Rojiar; Kienle, Achim
In: Magdeburg: Universitätsbibliothek, Dissertation Otto-von-Guericke-Universität Magdeburg, Fakultät für Elektrotechnik und Informationstechnik 2025, 1 Online-Ressource (xxiv, 117 Seiten, 1.92 MB) [Literaturverzeichnis: Seite 107-117]
2024
Dynamic modeling of particle size and porosity distribution in fluidized bed spray agglomeration
Otto, Eric; Dürr, Robert; Kienle, Achim; Bück, Andreas; Tsotsas, Evagelos
In: Computer aided chemical engineering - Amsterdam [u.a.] : Elsevier, Bd. 53 (2024), S. 163-168 [Symposium: 34th European Symposium on Computer Aided Process Engineering / 15th International Symposium on Process Systems Engineering, ESCAPE-34/PSE2024, Florence, Italy, 2-6 June 2024]
Improving the production of PHBV in cupriavidus necator by optimal control
Kok, Rudolph L., Johannes; Findeisen, Rolf; Kienle, Achim; Duvigneau, Stefanie
In: Computer aided chemical engineering - Amsterdam [u.a.] : Elsevier, Bd. 53 (2024), S. 2503-2508 [Symposium: 34th European Symposium on Computer Aided Process Engineering / 15th International Symposium on Process Systems Engineering, ESCAPE-34/PSE2024, Florence, Italy, 2-6 June 2024]
Multi-objective optimization of forced periodic operation of methanol synthesis in a fixed-bed reactor
Leiphold, Johannes; Nikolic, Daliborka; Seidel-Morgenstern, Andreas; Kienle, Achim
In: Computer aided chemical engineering - Amsterdam [u.a.] : Elsevier, Bd. 53 (2024), S. 1603-1608 [Symposium: 34th European Symposium on Computer Aided Process Engineering / 15th International Symposium on Process Systems Engineering, ESCAPE-34/PSE2024, Florence, Italy, 2-6 June 2024]
Mathematical modeling of an enzyme catalyzed transamination reaction with integrated product removal
Behrens, Jessica; Tiedemann, Sven; Langermann, Jan; Kienle, Achim
In: Computer aided chemical engineering - Amsterdam [u.a.] : Elsevier, Bd. 53 (2024), S. 721-726 [Symposium: 34th European Symposium on Computer Aided Process Engineering / 15th International Symposium on Process Systems Engineering, ESCAPE-34/PSE2024, Florence, Italy, 2-6 June 2024]
Hybrid modeling of PEM fuel cell - machine learning of equilibrium water content within a 1D cell model
Golovin, Ievgen; Knoppe, Kilian; Kunde, Christian; Kienle, Achim
In: Computer aided chemical engineering - Amsterdam [u.a.] : Elsevier, Bd. 53 (2024), S. 151-156 [Symposium: 34th European Symposium on Computer Aided Process Engineering / 15th International Symposium on Process Systems Engineering, ESCAPE-34/PSE2024, Florence, Italy, 2-6 June 2024]
Moving horizon estimation and control of a binary simulated moving bed chromatographic processes with Langmuir isotherms
Chernev, Valentin Plamenov; Kienle, Achim; Wouwer, Alain Vande
In: Computers & chemical engineering - Amsterdam [u.a.] : Elsevier Science, Bd. 189 (2024), Artikel 108804
Dynamic mode decomposition based MPC of fluidized bed spray agglomeration
Otto, Eric; Dürr, Robert; Bück, Andreas; Kienle, Achim
In: IFAC-PapersOnLine / Internationale Förderung für Automatische Lenkung - Frankfurt : Elsevier, Bd. 58 (2024), Heft 14, S. 694-699
Short-cut design of double-layer simulated moving bed chromatography for continuous ternary mixture separation - Langmuir isotherms
Lee, Ju Weon; Zarei, Somayeh; Kienle, Achim; Seidel-Morgenstern, Andreas
In: Industrial & engineering chemistry research - Columbus, Ohio : American Chemical Society, Bd. 63 (2024), Heft 39, S. 16873-16874
Population balance modeling of particle size and porosity in fluidized bed spray agglomeration
Otto, Eric; Ajalova, Aisel; Bück, Andreas; Tsotsas, Evangelos; Kienle, Achim
In: Industrial & engineering chemistry research - Columbus, Ohio : American Chemical Society, Bd. 63 (2024), Heft 41, S. 17545-17556
Moving horizon parameter estimation for an enzyme‐catalyzed transamination reaction with integrated product removal
Behrens, Jessica; Tiedemann, Sven; Kunde, Tom; Langermann und Erlencamp, von Jan; Kienle, Achim
In: Chemie - Ingenieur - Technik - Weinheim : Wiley-VCH Verl., Bd. 96 (2024), Heft 12, S. 1751-1766
Shortcut model to evaluate the performance of preferential crystallization for conglomerates forming chiral systems
Bhandari, Shashank; Kienle, Achim
In: Magdeburg: Universitätsbibliothek, Dissertation Otto-von-Guericke-Universität Magdeburg, Fakultät für Verfahrens- und Systemtechnik 2024, 1 Online-Ressource (142 Seiten, 4,61 MB) [Literaturverzeichnis: Seite 132-142][Literaturverzeichnis: Seite 132-142]
Model-based study of the regulation of biofilm growth by design of the porous substratum
Aamer, Emad; Faber, Felix; Bhaskaran, Supriya; Dürr, Robert; Bettenbrock, Katja; Kienle, Achim; Vorhauer-Huget, Nicole
In: SSRN eLibrary - [Erscheinungsort nicht ermittelbar] : Social Science Electronic Publ. . - 2024, insges. 37 S.
2023
Modeling and experimental validation of poly(3-Hydroxybutyrate-co-3-hydroxyvalerate) chain length distribution
Duvigneau, Stefanie; Wilisch-Neumann, Annette; Dürr, Robert; Kienle, Achim
In: Computer aided chemical engineering - Amsterdam [u.a.] : Elsevier, Bd. 52 (2023), S. 2223-2228
Modeling of particle formation in pan granulators with sieve-mill recycle
Dürr, Robert; Przywara, Mateusz; Otto, Eric; Antos, Dorota; Kienle, Achim
In: Computer aided chemical engineering - Amsterdam [u.a.] : Elsevier, Bd. 52 (2023), S. 1027-1032
Optimization of simulated moving bed chromatographic processes using surrogate models
Pishkari, Rojiar; Fechtner, Marcus; Keßler, Tobias; Kienle, Achim
In: Computer aided chemical engineering - Amsterdam [u.a.] : Elsevier, Bd. 52 (2023), S. 343-348
Towards machine learning of power-2-methanol processes
Martensen, Carl Julius; Plate, Christoph; Keßler, Tobias; Kunde, Christian; Kaps, Lothar; Kienle, Achim; Seidel-Morgenstern, Andreas; Sager, Sebastian
In: Computer aided chemical engineering - Amsterdam [u.a.] : Elsevier, Bd. 52 (2023), S. 561-568
Nonlinear behavior of methanol synthesis compared to CO2 methanation
Leipold, Johannes; Jung, Magnus; Keßler, Tobias; Kienle, Achim
In: Chemical engineering & technology - Weinheim : Wiley-VCH Verl.-Ges. . - 2023, insges. 7 S.
Stability of combined continuous granulation and agglomeration processes in a fluidized bed with sieve-mill-recycle
Otto, Eric; Dürr, Robert; Kienle, Achim
In: Processes - Basel : MDPI, Bd. 11 (2023), insges. 13 S.
Optimization of methanol synthesis under forced periodic operation in isothermal fixed-bed reactors
Leipold, Johannes; Seidel, Carsten; Nikolic, D.; Seidel-Morgenstern, Andreas; Kienle, Achim
In: Computers & chemical engineering - Amsterdam [u.a.] : Elsevier Science, Bd. 175 (2023), Artikel 108285
Modellierung und Optimierung erzwungener periodischer Betriebsweisen für die Methanolsynthese
Seidel, Carsten; Kienle, Achim
In: Magdeburg: Universitätsbibliothek, Dissertation Otto-von-Guericke-Universität Magdeburg, Fakultät für Elektrotechnik und Informationstechnik 2023, 1 Online-Ressource (xxiii, 209 Seiten, 3,34 MB) [Literaturverzeichnis: Seite 191-203]
Multiskalen-Modellierung der Polyhydroxyalkanoat-Biopolymer- und Influenza-A-Impfstoffproduktion
Duvigneau, Stefanie; Kienle, Achim
In: Magdeburg: Universitätsbibliothek, Dissertation Otto-von-Guericke-Universität Magdeburg, Fakultät für Elektrotechnik und Informationstechnik 2023, 1 Online-Ressource (vi, 167 Seiten, 10,89 MB) [Literaturverzeichnis: Seite 149-166][Literaturverzeichnis: Seite 149-166]
2022
Discrepancy-based control of particle processes
Otto, Eric; Behrens, Jessica; Palis, Stefan; Dürr, Robert; Kienle, Achim
In: Journal of process control - Amsterdam [u.a.] : Elsevier Science, Bd. 110 (2022), S. 99-109
Multiscale modeling of the microbial production of polyhydroxyalkanoates using two carbon sources
Duvigneau, Stefanie; Dürr, Robert; Wulkow, Michael; Kienle, Achim
In: Computers & chemical engineering - Amsterdam [u.a.] : Elsevier Science, Bd. 160 (2022), Artikel 107740, insges. 12 S.
Direct discretized kernel identification for continuous agglomeration processes
Otto, Eric; Maksakov, Anton; Dürr, Robert; Palis, Stefan; Kienle, Achim
In: IFAC-PapersOnLine / Internationale Förderung für Automatische Lenkung - Frankfurt : Elsevier, Bd. 55 (2022), Heft 7, S. 260-265
Bifurcation analysis of combined agglomeration and layering granulation in fluidized bed spray processes
Otto, Eric; Dürr, Robert; Kienle, Achim
In: 32nd European Symposium on Computer Aided Process Engineering - San Diego : Elsevier ; Montastruc, Ludovic . - 2022, S. 691-696
Global optimization for process design
Kunde, Christian; Kienle, Achim
In: Integrated Chemical Processes in Liquid Multiphase Systems - Berlin : De Gruyter ; Kraume, Matthias . - 2022, S. 433-449 [Kapitel 5.3.2]
Integrated solvent and process design
Linke, Steffen; Keßler, Tobias; Kunde, Christian; Kienle, Achim; Sundmacher, Kai
In: Integrated Chemical Processes in Liquid Multiphase Systems - Berlin : De Gruyter ; Kraume, Matthias . - 2022, S. 535-551 [Kapitel 6.4]
Deterministic global optimization of multistage layer melt crystallization using surrogate models and reduced space formulations
Kunde, Christian; Méndez, Ronald; Kienle, Achim
In: 32nd European Symposium on Computer Aided Process Engineering - San Diego : Elsevier ; Montastruc, Ludovic . - 2022, S. 727-732 [Konferenz: 32nd European Symposium on Computer Aided Process Engineering, Toulouse, 12.-15.06.2022]
Model Predictive Control of Simulated Moving Bed Chromatographic processes using Conservation Element/Solution Element method
Chernev, Valentin Plamenov; Santos, Lino O.; Wouver, Alain Vande; Kienle, Achim
In: IEEE Xplore digital library / Institute of Electrical and Electronics Engineers - New York, NY : IEEE . - 2022, S. 355-361 [Konferenz: 2022 26th International Conference on System Theory, Control and Computing (ICSTCC), 19-21 Oct. 2022; Sinaia, Romania]
Forced Periodic Operation of methanol synthesis in an isothermal gradientless reactor
Seidel, Carsten; Nikolić, Daliborka; Felischak, Matthias; Petkovska, Menka; Seidel-Morgenstern, Andreas; Kienle, Achim
In: Chemical engineering & technology - Weinheim : Wiley-VCH Verl.-Ges., Bd. 45 (2022), Heft 12, S. 2261-2272
Forced periodic operations of a chemical reactor for methanol synthesis - the search for the best scenario based on Nonlinear Frequency Response method. Part II: Simultaneous modulation of two inputs
Nikolić, Daliborka; Seidel, Carsten; Felischak, Matthias; Miličić, Tamara; Kienle, Achim; Seidel-Morgenstern, Andreas; Petkovska, Menka
In: Chemical engineering science - Amsterdam [u.a.] : Elsevier Science, Bd. 248 (2022), Artikel 117133
Integrated computer-aided molecular and process design - green solvents for the hydroformylation of long-chain olefines
Keßler, Tobias; Kunde, Christian; Linke, Steffen; Sundmacher, Kai; Kienle, Achim
In: Chemical engineering science - Amsterdam [u.a.] : Elsevier Science, Bd. 249 (2022), Artikel 117243
Forced periodic operations of a chemical reactor for methanol synthesis - the search for the best scenario based on Nonlinear Frequency Response method. Part I: Single input modulations
Nikolić, Daliborka; Seidel, Carsten; Felischak, Matthias; Miličić, Tamara; Kienle, Achim; Seidel-Morgenstern, Andreas; Petkovska, Menka
In: Chemical engineering science - Amsterdam [u.a.] : Elsevier Science, Bd. 248 (2022), Artikel 117134
Wave reflections in counter-current separation processes with unequal mass transfer coefficients
Fechtner, Marcus; Kienle, Achim
In: Chemical engineering science - Amsterdam [u.a.] : Elsevier Science, Bd. 260 (2022), Artikel 117929
2021
Fast, inexpensive, and reliable HPLC method to determine monomer fractions in poly(3-hydroxybutyrate-co-3-hydroxyvalerate)
Duvigneau, Stefanie; Kettner, Alexander; Carius, Lisa; Griehl, Carola; Findeisen, Rolf; Kienle, Achim
In: Applied microbiology and biotechnology - Berlin : Springer, Bd. 105 (2021), Heft 5, S. 4743-4749
Hybrid cybernetic modeling of the microbial production of polyhydroxyalkanoates using two carbon sources
Duvigneau, Stefanie; Dürr, Robert; Kranert, Lena; Wilisch-Neumann, Annette; Carius, Lisa; Findeisen, Rolf; Kienle, Achim
In: 31th European Symposium on Computer Aided Process Engineering , 2021 - Amsterdam : Elsevier ; Türkay, Metin - ESCAPE-31, S. 1969-1974 [Symposium: ESCAPE-31, Istanbul, 6-9 June 2021]
Advanced kinetic modeling of bio-co-polymer poly(3-hydroxybutyrate-co-3-hydroxyvalerate) production using fructose and propionate as carbon sources
Duvigneau, Stefanie; Dürr, Robert; Behrens, Jessica; Kienle, Achim
In: Processes - Basel : MDPI, Bd. 9 (2021), Heft 8, Artikel 1260, insges. 19 S.
Control of particle formation processes
Otto, Eric; Behrens, Jessica; Dürr, Robert; Palis, Stefan; Kienle, Achim
In: IFAC-PapersOnLine / Internationale Förderung für Automatische Lenkung - Frankfurt : Elsevier, Bd. 54 (2021), Heft 3, S. 231-236
Microbial production of polyhydroxyalkanoates - modeling of chain length distribution
Dürr, Robert; Duvigneau, Stefanie; Kienle, Achim
In: 31th European Symposium on Computer Aided Process Engineering , 2021 - Amsterdam : Elsevier ; Türkay, Metin, S. 1975-1982 [Symposium: ESCAPE-31, Istanbul, 6-9 June 2021]
Population balance modelling of pan granulation process
Otto, Eric; Dürr, Robert; Przywara, Mateusz; Antos, Dorota; Kienle, Achim
In: 31th European Symposium on Computer Aided Process Engineering , 2021 - Amsterdam : Elsevier ; Türkay, Metin - ESCAPE-31, S. 965-970 [Symposium: ESCAPE-31, Istanbul, 6-9 June 2021]
Multi-Rate data fusion for state and parameter estimation in (Bio-)chemical process engineering
Dürr, Robert; Duvigneau, Stefanie; Seidel, Carsten; Kienle, Achim; Bück, Andreas
In: Processes - Basel : MDPI, Bd. 9 (2021), Heft 11, Artikel 1990, insges. 16 S.
Kernel identification in continuous fluidized bed spray agglomeration from steady state data
Otto, Eric; Dürr, Robert; Strenzke, Gerd; Palis, Stefan; Bück, Andreas; Tsotsas, Evangelos; Kienle, Achim
In: Advanced powder technology - Amsterdam [u.a.] : Elsevier - Vol. 31 (2021), insgesamt 13 Seiten
EXPERIMENTAL INVESTIGATION OF PROCESS BEHAVIOUR OF CONTINUOUS FLUIDIZED BED SPRAY AGGLOMERATION WITH INTERNAL CLASSIFICATION
Strenzke, Gerd; Dürr, Robert; Bück, Andreas; Kienle, Achim; Tsotsas, Evangelos
In: Proceedings of the13th International Conference on Fluidized Bed Technology , 2021 - Vancouver, Canada : GLAB Reactor and Fluidization Technologies ; Bi, Xiaotao, S. 374-379 [Konferenz: CFB 13, Vancouver, Canada, May 10-14, 2021]
Process behavior and product quality in fertilizer manufacturing using continuous hopper transfer pan granulation - experimental investigations
Przywara, Mateusz; Dürr, Robert; Otto, Eric; Kienle, Achim; Antos, Dorota
In: Processes - Basel : MDPI, Bd. 9 (2021), Heft 8, Artikel 1439, insges. 18 S.
Optimization of methanol synthesis under forced periodic operation
Seidel, Carsten; Nikolić, Daliborka; Felischak, Mattias; Petkovska, Menka; Seidel-Morgenstern, Andreas; Kienle, Achim
In: Processes - Basel : MDPI - open access journal, Bd. 9 (2021), Heft 5, Artikel 872
Approximate shock layer solutions for the separation of multicomponent mixtures with different axial dispersion or mass transfer coefficients
Fechtner, Marcus; Kienle, Achim
In: Chemical engineering science - Amsterdam [u.a.] : Elsevier Science - Volume 231 (2021), article 116335
Modelling and controlling of particle formation processes
Dürr, Robert; Otto, Eric; Kienle, Achim
In: Naukovi praci Donecʹkoho Nacionalʹnoho Techničnoho Universytetu / Problemi modeljuvannja ta avtomatizaciï proektuvannja / Donec'kyj Nacional'nyj Techničnyj Universytet - Donecʹk, Bd. 17 (2021), Heft 1, S. 66-72
Numerical short-cut design of simulated moving bed chromatography for multicomponent nonlinear adsorption isotherms - nonstoichiometric Langmuir model
Lee, Ju Weon; Kienle, Achim; Seidel-Morgenstern, Andreas
In: Industrial & engineering chemistry research - Columbus, Ohio : American Chemical Society, Bd. 60 (2021), Heft 29, S. 10455-10834 [This article is part of the Giuseppe Storti Festschrift special issue.]
Model-based control for active damping of crane structural vibrations
Golovin, Ievgen; Kienle, Achim
In: Magdeburg, Dissertation Otto-von-Guericke-Universität Magdeburg, Fakultät für Elektrotechnik und Informationstechnik 2021, ii, 129 Seiten [Literaturverzeichnis: Seite 115-123][Literaturverzeichnis: Seite 115-123]
2020
Hybrid cybernetic modeling of polyhydroxyalkanoate production in cupriavidus necator using fructose and acetate as substrates
Duvigneau, Stefanie; Dürr, Robert; Carius, Lisa; Kienle, Achim
In: IFAC-PapersOnLine / Internationale Förderung für Automatische Lenkung - Frankfurt : Elsevier, Bd. 53 (2020), Heft 2, S. 16872-16877
Process control
Engell, Sebastian; Kienle, Achim
In: Preparative Chromatography , Third edition - Weinheim : Wiley-VCH . - 2020, S. 504-524 [Kapitel 9]
Methanol kinetics from optimal dynamic experiments
Seidel, Carsten; Kienle, Achim
In: 30th European Symposium on Computer Aided Chemical Engineering / European Symposium on Computer Aided Process Engineering , 2020 - Amsterdam : Elsevier ; Pierucci, Sauro, S. 7-12 [Symposium: ESCAPE30, May 24-27, 2020, Milan, Italy]
Dynamics of spray granulation in continuously operated horizontal fluidized beds
Neugebauer, Christoph; Diez, Eugen; Mielke, Lisa; Palis, Stefan; Bück, Andreas; Tsotsas, Evangelos; Kienle, Achim; Heinrich, Stefan
In: Dynamic flowsheet simulation of solids processes - Cham : Springer Nature Switzerland AG 2020 ; Heinrich, Stefan, S. 67-107 [Chapter 3]
Computer aided molecular design of green solvents for the hydroformylation of long-chain olefines
Keßler, Tobias; Kunde, Christian; Linke, Steffen; McBride, Kevin; Sundmacher, Kai; Kienle, Achim
In: 30th European Symposium on Computer Aided Process Engineering , 2020 - Amsterdam : Elsevier, S. 745-750 [Symposium: ESCAPE30, May 24-27, 2020, Milan, Italy]
Inferential control of product properties for fluidized bed spray granulation layering
Dürr, Robert; Neugebauer, Christoph; Palis, Stefan; Bück, Andreas; Kienle, Andreas
In: IFAC-PapersOnLine / Internationale Förderung für Automatische Lenkung - Frankfurt : Elsevier, Bd. 53 (2020), Heft 2, S. 11410-11415
Model-based approach for predicting the impact of genetic modifications on product yield in biopharmaceutical manufacturing-Application to influenza vaccine production
Duvigneau, Stefanie; Dürr, Robert; Laske, Tanja; Bachmann, Mandy; Dostert, Melanie; Kienle, Achim
In: PLoS Computational Biology / Public Library of Science - San Francisco, Calif. : Public Library of Science - Volume 16 (2020), issue 6, article e1007810, 22 pages
Fast and accurate simulation of simulated moving bed chromatographic processes with linear adsorption isotherms
Pishkari, Rojiar; Kienle, Achim
In: 30th European Symposium on Computer Aided Chemical Engineering / European Symposium on Computer Aided Process Engineering , 2020 - Amsterdam : Elsevier ; Pierucci, Sauro, S. 487-492 [Symposium: ESCAPE30, May 24-27, 2020, Milan, Italy]
Rational design of ion exchange simulated moving bed processes
Fechtner, Marcus; Kienle, Achim
In: 30th European Symposium on Computer Aided Chemical Engineering / European Symposium on Computer Aided Process Engineering , 2020 - Amsterdam : Elsevier ; Pierucci, Sauro, S. 733-738 [Symposium: ESCAPE30, May 24-27, 2020, Milan, Italy]
On-line optimization of four-zone simulated moving bed chromatography using an equilibrium-dispersion model: I. Simulation study
Lee, Ju Weon; Kienle, Achim; Seidel-Morgenstern, Andreas
In: Chemical engineering science - Amsterdam [u.a.]: Elsevier Science, Volume 225 (2020), article 115810
Examining sodium and potassium channel conductances involved in hyperexcitability of chemotherapy-induced peripheral neuropathy - a mathematical and cell culture-based study
Verma, Parul; Eaton, Muriel; Kienle, Achim; Flockerzi, Dietrich; Yang, Yang; Ramkrishna, Doraiswami
In: Frontiers in computational neuroscience - Lausanne : Frontiers Research Foundation - Vol. 14 (2020), Article 564980
Robust control of fluidized bed layering granulation
Neugebauer, Christoph; Seidel, Carsten; Palis, Stefan; Kienle, Achim
In: IFAC-PapersOnLine / Internationale Förderung für Automatische Lenkung - Frankfurt : Elsevier, Bd. 53 (2020), Heft 2, S. 11422-11427
Computational analysis of a 9D model for a small DRG neuron
Verma, Parul; Kienle, Achim; Flockerzi, Dietrich; Ramkrishna, Doraiswami
In: Journal of computational neuroscience - Dordrecht [u.a.] : Springer Science + Business Media B.V, Bd. 48 (2020), S. 429-444
Lyapunov-based online parameter estimation for continuous fluidized bed layering granulation
Otto, Eric; Neugebauer, Christoph; Palis, Stefan; Kienle, Achim
In: IFAC-PapersOnLine / Internationale Förderung für Automatische Lenkung - Frankfurt : Elsevier, Bd. 53 (2020), Heft 2, S. 11398-11403
Efficient simulation of chromatographic processes using the conservation element/solution element method
Chernev, Valentin Plamenov; Wouwer, Alain Vande; Kienle, Achim
In: Processes - Basel : MDPI - Vol. 8 (2020), 10, Artikelnr. 1316, insgesamt 19 Seiten [This article belongs to the Special Issue Advanced Methods in Process and Systems Engineering]
Corrigendum to Kinetic modeling of methanol synthesis from renewable resources (Chem. Eng. Sci. 175 (2018), 130-138)
Seidel, Carsten; Jörke, A.; Vollbrecht, B.; Seidel-Morgenstern, Andreas; Kienle, Achim
In: Chemical engineering science - Amsterdam [u.a.] : Elsevier Science - Volume 223 (2020), article 115724
Using bifurcation theory for exploring pain
Verma, Parul; Kienle, Achim; Flockerzi, Dietrich; Ramkrishna, Doraiswami
In: Industrial & engineering chemistry research - Columbus, Ohio : American Chemical Society, Bd. 59 (2020), Heft 6, S. 2524-2535
On-line optimization of four-zone simulated moving bed chromatography using an Equilibrium-Dispersion Model: II. Experimental validation
Lee, Ju Weon; Kienle, Achim; Seidel-Morgenstern, Andreas
In: Chemical engineering science - Amsterdam [u.a.] : Elsevier Science - Volume 226 (2020), article 115808
Modeling, dynamics and control of continuous fluidized bed layering granulation processes
Neugebauer, Christoph; Kienle, Achim; Palis, Stefan
In: Magdeburg, Dissertation Otto-von-Guericke-Universität Magdeburg, Fakultät für Elektrotechnik und Informationstechnik 2020, xii, 139 Seiten [Literaturverzeichnis: Seite 121-131][Literaturverzeichnis: Seite 121-131]
Modeling and simulation of enzyme controlled metabolic networks using optimization based methods
Lindhorst, Henning; Kienle, Achim
In: Magdeburg, Dissertation Otto-von-Guericke-Universität Magdeburg, Fakultät für Elektrotechnik und Informationstechnik 2020, III, 133 Seiten [Literaturverzeichnis: Seite 121-129][Literaturverzeichnis: Seite 121-129]
2019
Lyapunov-based online parameter estimation in continuous fluidized bed spray agglomeration processes
Golovin, Ievgen; Otto, Eric; Dürr, Robert; Palis, Stefan; Kienle, Achim
In: IFAC-PapersOnLine / Internationale Förderung für Automatische Lenkung - Frankfurt : Elsevier, Bd. 52 (2019), Heft 1, S. 329-334
Global optimization of distillation columns using explicit and implicit surrogate models
Keßler, Tobias; Kunde, Christian; McBride, Kevin; Mertens, Nick; Michaels, Dennis; Sundmacher, Kai; Kienle, Achim
In: Chemical engineering science - Amsterdam [u.a.] : Elsevier Science, Bd. 197 (2019), S. 235-245
Multi-mode model predictive control and estimation for uncertain biotechnological processes
Morabito, Bruno; Kienle, Achim; Findeisen, Rolf; Carius, Lisa
In: IFAC-PapersOnLine - Frankfurt : Elsevier, Bd. 52 (2019), Heft 1, S. 709-714 [Part of special issue: 12th IFAC Symposium on Dynamics and Control of Process Systems, including Biosystems DYCOPS 2019: Florianópolis, Brazil, 2326 April 2019]
Systematic selection of green solvents and process optimization for the hydroformylation of long-chain olefines
Keßler, Tobias; Kunde, Christian; Linke, Steffen; McBride, Kevin; Sundmacher, Kai; Kienle, Achim
In: Processes - Basel : MDPI - Volume 7 (2019), 12, Artikel 882 [This article belongs to the Special Issue Advanced Methods in Process and Systems Engineering]
On the dynamics and control of continuous fluidized bed layering granulation with screen-mill-cycle
Neugebauer, Christoph; Diez, Eugen; Bück, Andreas; Palis, Stefan; Heinrich, Stefan; Kienle, Achim
In: Powder technology - Amsterdam [u.a.] : Elsevier Science, Bd. 354 (2019), S. 765-778 [Sonstige Körperschaft: Technische Universität Hamburg; Sonstige Körperschaft: Technische Universität Hamburg, Institute of Solids Process Engineering & Particle Technology]
Equilibrium theory of ion exchange chromatography with variable solution normality and steric hindrance
Fechtner, Marcus; Kienle, Achim
In: Chemical engineering science - Amsterdam [u.a.] : Elsevier Science, Bd. 199 (2019), S. 508-527
Surrogate modeling for liquidliquid equilibria using a parameterization of the binodal curve
Kunde, Christian; Keßler, Tobias; Linke, Steffen; McBride, Kevin; Sundmacher, Kai; Kienle, Achim
In: Processes - Basel : MDPI - Volume 7 (2019), 10, Artikel 753 [This article belongs to the Special Issue Advanced Methods in Process and Systems Engineering]
Online estimation of optimal operating conditions for simulated moving bed chromatographic processes
Suvarov, Paul; Lee, Ju Weon; Vande Wouwer, Alain; Seidel-Morgenstern, Andreas; Kienle, Achim
In: Journal of chromatography - New York, NY [u.a.] : Science Direct, Bd. 1602 (2019), S. 266-272
Discrete modeling of drying induced ion transport and crystallization in porous media
Rahimi, Arman; Tsotsas, Evangelos; Kienle, Achim
In: Magdeburg, Dissertation Otto-von-Guericke-Universität Magdeburg, Fakultät für Verfahrens- und Systemtechnik 2019, xv, 153 Seiten [Literaturverzeichnis: Seite 117-127][Literaturverzeichnis: Seite 117-127]
Mathematische Modellierung und Simulation von in-silico Protozellen nach dem Modularisierungs- und Baukastenprinzip
Schneider, Eugenia; Kienle, Achim
In: Magdeburg, Dissertation Otto-von-Guericke-Universität Magdeburg, Fakultät für Elektrotechnik und Informationstechnik 2019, xiv, 115 Seiten [Literaturverzeichnis: Seite 103-115][Literaturverzeichnis: Seite 103-115]
2018
Parameter identification for continuous fluidized bed spray agglomeration
Golovin, Ivgen; Strenzke, Gerd; Wegner, Maximilian; Palis, Stefan; Bück, Andreas; Kienle, Achim; Tsotsas, Evangelos
In: 6th International Conference on Population Balance Modelling - Ghent, Belgium : Ghent University . - 2018, insges. 4 S. [Konferenz: PBM 2018, Ghent, Belgium, 6 - 9 May]
Efficient simulation of ion exchange chromatography with application to bioseparations
Fechtner, Marcus; Kaspereit, Malte; Kienle, Achim
In: Computer aided chemical engineering - Amsterdam [u.a.] : Elsevier, Bd. 43 (2018), S. 295-300 [Symposium: 28th European Symposium on Computer Aided Process Engineering, Graz, Austria, 10-13 June 2018]
Kinetic modeling of methanol synthesis - impact of catalyst deactivation
Seidel, Carsten; Jörke, Andreas; Vollbrecht, Bert; Seidel-Morgenstern, Andreas; Kienle, Achim
In: Computer aided chemical engineering - Amsterdam [u.a.] : Elsevier, Bd. 43 (2018), S. 85-90 [Symposium: 28th European Symposium on Computer Aided Process Engineering, Graz, Austria, 10-13 June 2018]
Parameter identification for continuous fluidized bed spray agglomeration
Golovin, Ievgen; Strenzke, Gerd; Dürr, Robert; Palis, Stefan; Bück, Andreas; Tsotsas, Evangelos; Kienle, Achim
In: Processes - Basel : MDPI - Vol. 6.2018, 12, Artikel 246
Influence of thermal conditions on particle properties in fluidized bed layering granulation
Neugebauer, Christoph; Bück, Andreas; Palis, Stefan; Mielke, Lisa; Tsotsas, Evangelos; Kienle, Achim
In: 6th International Conference on Population Balance Modelling - Ghent, Belgium : Ghent University . - 2018, insges. 8 S. [Konferenz: PBM 2018, Ghent, Belgium, 6 - 9 May]
Mathematical modeling as a tool to improve influenza vaccine production processes
Duvigneau, Stefanie; Dürr, Robert; Laske, Tanja; Bachmann, Mandy; Dostert, Melanie; Reichl, Udo; Kienle, Achim
In: IFAC-PapersOnLine / Internationale Förderung für Automatische Lenkung - Frankfurt : Elsevier, Bd. 51 (2018), Heft 19, S. 1-4
Influence of drying conditions on process properties and parameter identification for continuous fluidized bed spray agglomeration
Strenzke, Gerd; Golovin, Ievgen; Wegner, M.; Palis, Stefan; Bück, Andreas; Kienle, Achim; Tsotsas, Evangelos
In: IDS 2018 / International Dryign Symposium , .2018 - València, Spain : Universitat ; Cárcel, Juan Andrés, S. 579-586 [Konferenz: IDS 2018]
Efficient simulation and equilibrium theory for adsorption processes with implicit adsorption isotherms - ideal adsorbed solution theory
Fechtner, Marcus; Kienle, Achim
In: Chemical engineering science - Amsterdam [u.a.] : Elsevier Science, Bd. 177 (2018), S. 284-292
Kinetic modeling of methanol synthesis from renewable resources
Seidel, Carsten; Jörke, A.; Vollbrecht, B.; Seidel-Morgenstern, Andreas; Kienle, Achim
In: Chemical engineering science - Amsterdam [u.a.] : Elsevier Science, Bd. 175 (2018), S. 130-138
Model-based state estimation based on hybrid cybernetic models
Carius, Lisa; Pohlodek, J.; Morabito, Bruno; Franz, A.; Mangold, M.; Findeisen, Rolf; Kienle, Achim
In: IFAC-PapersOnLine / Internationale Förderung für Automatische Lenkung - Frankfurt : Elsevier, Bd. 51 (2018), Heft 18, S. 197-202 [Symposium: 10th IFAC Symposium on Advanced Control of Chemical Processes, ADCHEM 2018, Shenyang, China, 25-27 July 2018]
Monotonic reformulation and bound tightening for global optimization of ideal multi-component distillation columns
Mertens, Nick; Kunde, Christian; Kienle, Achim; Michaels, Dennis
In: Optimization and engineering - Dordrecht [u.a.] : Springer Science + Business Media B.V, Bd. 19 (2018), Heft 2, S. 479-514
Global optimization of distillation columns using surrogate models
Keßler, Tobias; Kunde, Christian; Mertens, Nick; Michaels, Dennis; Kienle, Achim
In: SN applied sciences - [Cham] : Springer International Publishing - Vol. 1.2019, Artikel 27 [Online first]
Influence of thermal conditions on particle properties in fluidized bed layering granulation
Neugebauer, Christoph; Bück, Andreas; Palis, Stefan; Mielke, Lisa; Tsotsas, Evangelos; Kienle, Achim
In: Processes - Basel : MDPI - Vol. 6.2018, 12, Artikel 235
Global optimization of multistage binary separation networks
Kunde, Christian; Kienle, Achim
In: Chemical engineering and processing - Amsterdam [u.a.] : Elsevier, Bd. 131 (2018), S. 164-177
Dynamic methods for thermodynamic equilibrium calculations in process simulation and process optimization
Zinser, Alexander; Sundmacher, Kai; Kienle, Achim
In: Magdeburg, Dissertation Otto-von-Guericke-Universität Magdeburg, Fakultät für Verfahrens- und Systemtechnik 2018, xvi, 128 Seiten [Literaturverzeichnis: Seite 117-125][Literaturverzeichnis: Seite 117-125]
Magdeburger Automatisierungstechnik im Wandel - vom Industrie- zum Forschungsstandort
Neumann, Peter; Diedrich, Christian; Höltge, Rolf; Jumar, Ulrich; Kienle, Achim; Krampitz, Reinhold; Müller, Günter; Pusch, Konrad; Rokosch, Helga; Schmidt, Barbara; Schmucker, Ulrich; Unger, Gerhard; Wolf, Günter
In: Magdeburg: Otto-von-Guericke-Universität, 2018, 223 Seiten, ISBN: 978-3-944722-75-7
2017
Online parameter identification for continuous fluidized bed spray granulation with external sieve-mill cycle
Palis, Stefan; Kienle, Achim
In: IEEE Xplore digital library / Institute of Electrical and Electronics Engineers - New York, NY : IEEE . - 2017, S. 594-598 [Konferenz: 22nd International Conference on Methods and Models in Automation and Robotics (MMAR), Miedzyzdroje, Poland, 2017]
Process dynamics of continuous fluidised bed layering granulation
Bück, Andreas; Schmidt, Martin; Neugebauer, Christoph; Palis, Stefan; Kienle, Achim; Heinrich, Stefan; Tsotsas, Evangelos
In: 8th International Granulation Workshop - Sheffield - Posternr. 2, paper 67, insgesamt 5 Seiten
Global optimization of distillation columns using surrogate models
Keßler, Tobias; Kunde, Christian; Mertens, Nick; Michaels, Dennis; Kienle, Achim
In: Evolutionary and deterministic methods for design optimization and control with applications to industrial and societal problems : Sep 13-15, 2017 in Madrid, Spain ; EUROGEN 2017 ; Book of abstracts - Madrid : Technical University ; Andrés, Esther - 2017, paper 041, insgesamt 7 Seiten
Efficient global optimization of a novel hydroformylation process
Keßler, Tobias; Mertens, Nick; Kunde, Christian; Nentwich, Corina; Michaels, Dennis; Kienle, Achim
In: 27th European symposium on computer aided process engineering - Amsterdam : Elsevier ; Espuña, Antonio . - 2017, S. 2113-2118 [Konferenz: ESCAPE 2017]
Control of continuous mixed-solution mixed-product removal crystallization processes
Geyyer, Rostyslav; Dürr, Robert; Temmel, Erik; Li, Tao; Lorenz, Heike; Palis, Stefan; Seidel-Morgenstern, Andreas; Kienle, Achim
In: Chemical engineering & technology - Weinheim : Wiley-VCH Verl.-Ges., Bd. 40 (2017), Heft 7, S. 1362-1369
A dynamic two-zone model of continuous fluidized bed layering granulation with internal product classification
Neugebauer, Christoph; Palis, Stefan; Bück, Andreas; Tsotsas, Evangelos; Heinrich, Stefan; Kienle, Achim
In: Particuology - Amsterdam : Elsevier, Bd. 31 (2017), S. 8-14
Efficient simulation and equilibrium theory for adsorption processes with implicit adsorption isotherms - mass action equilibria
Fechtner, Marcus; Kienle, Achim
In: Chemical engineering science - Amsterdam [u.a.] : Elsevier Science, Bd. 171 (2017), S. 471-480
Analysis and design of center-cut separations using 8-zone simulated moving bed chromatography
Santos da Silva, Francisco Vitor; Kienle, Achim; Seidel-Morgenstern, Andreas
In: Magdeburg, Dissertation Otto-von-Guericke-Universität Magdeburg, Fakultät für Verfahrens- und Systemtechnik 2017, 161 Seiten [Literaturverzeichnis: Seite 142-153][Literaturverzeichnis: Seite 142-153]
Global optimization in conceptual process design
Kunde, Christian; Kienle, Achim; Seidel-Morgenstern, Andreas
In: Magdeburg, Dissertation Otto-von-Guericke-Universität Magdeburg, Fakultät für Elektrotechnik und Informationstechnik 2017, i, 123 Seiten [Literaturverzeichnis: Seite 117-123][Literaturverzeichnis: Seite 117-123]
Investigating arsenic and osmotic stress response in yeast saccharomyces cerevisiae using mathematical modeling and model selection
Rastgou Talemi, Soheil Soheil Rastgou; Kienle, Achim Achim
In: Magdeburg, Dissertation Otto-von-Guericke-Universität Magdeburg, Fakultät für Elektrotechnik und Informationstechnik 2016, XII, 124 Seiten
2016
Analyzing the impact of heterogeneity in genetically engineered cell lines for influenza vaccine production using population balance modeling
Dürr, Robert; Duvigneau, Stefanie; Laske, Tanja; Bachmann, Mandy; Kienle, Achim
In: IFAC-PapersOnLine / Internationale Förderung für Automatische Lenkung - Frankfurt : Elsevier, Bd. 49 (2016), Heft 26, S. 225-230
Control of MSMPR crystallization processes
Geyyer, Rostyslaw; Dürr, Robert; Temmel, E.; Li, T.; Lorenz, H.; Palis, Stefan; Seidel-Morgenstern, Andreas; Kienle, Achim
In: BIWIC 2016 , 2016 , 1. Auflage - Göttingen : Cuvillier Verlag, S. 335-341 [Kongress: 23rd International Workshop on Industrial Crystallization, BIWIC 2016, Magdeburg, 6-8 September, 2016]
A reformulation strategy for deterministic global optimization of ideal multi-component distillation processes
Mertens, Nick; Kunde, Christian; Kienle, Achim; Michaels, Dennis
In: Computer aided chemical engineering - Amsterdam [u.a.] : Elsevier, Bd. 38 (2016), S. 691-696 [Kongress: 26th European Symposium on Computer Aided Process Engineering]
Influence of mill characteristics on stability of continuous layering granulation with external product classification
Neugebauer, Christoph; Palis, Stefan; Bück, Andreas; Diez, Eugen; Heinrich, Stefan; Tsotsas, Evangelos; Kienle, Achim
In: Computer aided chemical engineering - Amsterdam [u.a.] : Elsevier, Bd. 38 (2016), S. 1275-1280 [Kongress: 26th European Symposium on Computer Aided Process Engineering]
An efficient approximate moment method for multi-dimensional population balance models - application to virus replication in multi-cellular systems
Dürr, Robert; Müller, Thomas; Duvigneau, Stefanie; Kienle, Achim
In: Chemical engineering science - Amsterdam [u.a.] : Elsevier Science . - 2016
Control of incomplete separation in simulated moving bed chromatographic processes
Suvarov, Paul; Wouwer, Alain vande; Lee, Ju Weon; Seidel-Morgensten, Andreas; Kienle, Achim
In: IFAC-PapersOnLine / Internationale Förderung für Automatische Lenkung - Frankfurt : Elsevier, Bd. 49 (2016), Heft 7, S. 153-158 [Kongress: 11th IFAC Symposium on Dynamics and Control of Process SystemsIncluding Biosystems, DYCOPS-CAB 2016, Trondheim, Norway, 6-8 June, 2016]
Modeling and simulation of particulate processes
Kienle, Achim; Palis, Stefan; Mangold, Michael; Dürr, Robert
In: Ėlektronnoe modelirovanie - Kiev : Naukova Dumka, Bd. 38 (2016), Heft 5, S. 23-34
Influence of operation parameters on process stability in continuous fluidised bed layering with external product classification
Bück, Andreas; Neugebauer, Christoph; Meyer, Katja; Palis, Stefan; Diez, Eugen; Kienle, Achim; Heinrich, Stefan; Tsotsas, Evangelos
In: Powder technology - Amsterdam [u.a.] : Elsevier Science, Bd. 300 (2016), S. 37-45 [Kongress: 7th International Granulation Workshop 2015: Granulation across the length scales]
Untersuchung des dynamischen Verhaltens der Sprühgranulation in kontinuierlich betriebenen Wirbelschichtrinnen
Diez, E.; Heinrich, S.; Meyer, Katja; Tsotsas, Evangelos; Neugebauer, C.; Kienle, Achim
In: Chemie - Ingenieur - Technik - Weinheim : Wiley-VCH Verl., Bd. 88 (2016), Heft 9, S. 1359-1360 [Special Issue: ProcessNet-Jahrestagung und 32. DECHEMA-Jahrestagung der Biotechnologen 2016]
Deterministic global optimization in conceptual process design of distillation and melt crystallization
Kunde, Christian; Michaels, Dennis; Micovic, Jovana; Lutze, Philip; Górak, Andrzej; Kienle, Achim
In: Chemical engineering and processing - Amsterdam [u.a.] : Elsevier, Bd. 99 (2016), S. 132-142
Parameter estimation and method of moments for multi dimensional population balance equations with application to vaccine production processes
Dürr, Robert; Kienle, Achim; Thévenin, Dominique
In: Magdeburg, Dissertation Otto-von-Guericke-Universität Magdeburg, Fakultät für Elektrotechnik und Informationstechnik 2016, ii , 151 Seiten [Literaturverzeichnis: Seite 141-150][Literaturverzeichnis: Seite 141-150]
Modellbasierte Bestimmung von Interventionsstrategien zur Optimierung der Produktion von Biokraftstoffen in Cyanobakterien
Erdrich, Philipp; Reichl, Udo; Kienle, Achim
In: Magdeburg, Dissertation Otto-von-Guericke-Universität Magdeburg, Fakultät für Verfahrens- und Systemtechnik 2016, xx, 158 Seiten [Literaturverzeichnis: Seite 131-158][Literaturverzeichnis: Seite 131-158]
Development of an efficient method for simulating fixed-bed adsorption dynamics using Ideal Adsorbed Solution Theory
Rubiera Landa, Héctor Octavio; Kienle, Achim
In: Magdeburg, Dissertation Otto-von-Guericke-Universität Magdeburg, Fakultät für Verfahrens- und Systemtechnik 2016, xxii, 227 Seiten [Literaturverzeichnis: Seite 195-222][Literaturverzeichnis: Seite 195-222]
Modellbasierte Analysen zur Gestaltung und Betriebsführung von Biogasanlagen
Bensmann, Astrid Lilian; Sundmacher, Kai; Kienle, Achim
In: München: Dr. Hut, Dissertation Otto-von-Guericke-Universität Magdeburg, Fakultät für Verfahrens- und Systemtechnik 2016, xiv, 149 Seiten - (Verfahrenstechnik), ISBN: 978-3-8439-2908-0 [Literaturverzeichnis: Seite 135-144][Literaturverzeichnis: Seite 135-144]
Robuste Regelung von Simulated Moving Bed Chromatographieprozessen
Suvarov, Paul; Kienle, Achim
In: Magdeburg, Dissertation Université de Mons 2016 Dissertation Otto-von Guericke-Universität Magdeburg, Fakultät für Elektrotechnik und Informationstechnik 2016, 114 Seiten [englischer Titel: Robust control methods for Simulated Moving Bed chromatographic separation processes; Literaturverzeichnis: Seite 104-107][englischer Titel: Robust control methods for Simulated Moving Bed chromatographic separation processes; Literaturverzeichnis: Seite 104-107]
Analyzing the impact of heterogeneity in genetically engineered cell lines for influenza vaccine production using population balance modeling
Dürr, Robert; Duvigneau, Stefanie; Laske, Tanja; Bachmann, Mandy; Kienle, Achim
In: FOSBE 2016 - Magdeburg ; Findeisen, Rolf - 2016, Art. TuPP.1, S. 32 [Kongress: 6th International Conference on Foundations of Systems Biology in Engineering, FOSBE 2016, Magdeburg, Germany, October 9-12,2016]
Control of multi-chamber continuous fluidized bed spray granulation
Palis, Stefan; Neugebauer, Christoph; Bück, Andreas; Heinrich, Stefan; Tsotsas, Evangelos; Kienle, Achim
In: PARTEC 2016 - Nürnberg, insges. 4 S.
2015
Deterministic global optimization of multistage melt crystallization processes in hydroformylation
Kunde, Christian; Kienle, Achim
In: 12th International Symposium on Process Systems Engineering and 25th European Symposium on Computer Aided Process Engineering - Amsterdam [u.a.] : Elsevier . - 2015, S. 1061-1066 - (Computer-aided chemical engineering; 37)
Efficient DQMOM for multivariate population balance equations and application to virus replication in cell cultures
Dürr, Robert; Müller, Thomas; Kienle, Achim
In: 8th Vienna International Conference on Mathematical Modelling 2015 - IFAC ; Breitenecker, Felix, S. 29-34
Online parameter identification of facet growth kinetics in crystal morphology population balance models
Dürr, Robert; Palis, Stefan; Kienle, Achim
In: Procedia engineering - Amsterdam [u.a.] : Elsevier, Bd. 102 (2015), S. 1336-1345
Auto-tuning control systems for improved operation of continuous fluidized bed spray granulation processes with external product classification
Palis, Stefan; Dreyschultze, Christian; Neugebauer, Christoph; Kienle, Achim
In: Procedia engineering - Amsterdam [u.a.] : Elsevier, Bd. 102 (2015), S. 133-141
Influence of zone formation on stability of continuous fluidized bed layering granulation with external product classification
Dreyschultze, Christian; Neugebauer, Christoph; Palis, Stefan; Bück, Andreas; Tsotsas, Evangelos; Heinrich, Stefan; Kienle, Achim
In: Particuology - Amsterdam : Elsevier, Bd. 23 (2015), S. 1-7
Combination of limited measurement information and multidimensional population balance models
Dürr, Robert; Franz, André; Kienle, Achim
In: IFAC-PapersOnLine / Internationale Förderung für Automatische Lenkung - Frankfurt : Elsevier, Bd. 48 (2015), Heft 20, S. 261-166
Entropy-based control of continuous Fluidized bed spray granulation processes
Palis, Stefan; Bück, Andreas; Kienle, Achim
In: IFAC-PapersOnLine / Internationale Förderung für Automatische Lenkung - Frankfurt : Elsevier, Bd. 48 (2015), Heft 13, S. 154-157 [Kongress: 5th IFAC Workshop on Lagrangian and Hamiltonian Methods for Nonlinear Control LHMNC 2015, Lyon, France, 4-7 July 2015]
Deterministic global optimization of binary hybrid distillation/melt-crystallization processes based on relaxed MINLP formulations
Ballerstein, Martin; Kienle, Achim; Kunde, Christian; Michaels, Dennis; Weismantel, Robert
In: Optimization and engineering - Dordrecht [u.a.] : Springer Science + Business Media B.V, Bd. 16 (2015), Heft 2, S. 409-440
Robust control of continuous crystallization processes
Geyyer, Rostyslav; Kienle, Achim; Palis, Stefan
In: IFAC-PapersOnLine / Internationale Förderung für Automatische Lenkung - Frankfurt : Elsevier, Bd. 48 (2015), Heft 11, S. 598-603 [Kongress: 1st IFAC Conference on Modelling, Identification and Control of Nonlinear Systems MICNON 2015, Saint Petersburg, Russia, 24-26 June 2015]
Nonlinear dynamics of Poly(hydroxyalkanoate) production in Ralstonia eutropha and Rhodospirillum rubrum
Franz, André; Kienle, Achim
In: Magdeburg, Univ., Fak. für Elektrotechnik und Informationstechnik, Diss., 2015, XIX, 134 S.
Influence of operation parameters onprocess stability in conzinuous fluidised bed layering with external classification
Bück, Andreas; Neugebauer, Christoph; Meyer, Katja; Palis, Stefan; Diez, Eugen; Kienle, Achim; Heinrich, Stefan; Tsotsas, Evangelos
In: 7th International Granulation Workshop - Sheffield . - 2015, insges. 11 S.
2014
Auto-tuning of multivariable PI/PID controllers using iterative feedback tuning - design examples
Sommer, Steffen; Nguyen, Hoang; Kienle, Achim
In: 24th European Symposium on Computer Aided Process Engineering: [ESCAPE-24, held in Budapest, Hungary, from 15 to 18 June 2014] - Amsterdam [u.a.] : Elsevier ; Klemeš, Jiři Jaromír Pt. A, S. 721-726 - (Computer-aided chemical engineering; 33) Kongress: ESCAPE 24 Budapest, Hungary 2014.06.15-18
Population balance modeling of biopolymer production in cellular systems (I)
Franz, André; Dürr, Robert; Kienle, Achim
In: Proceedings of the 19th IFAC world congress 2014 - IFAC ; Boje, Edward, S. 1705-1710 Kongress: IFAC World Congress 19 Cape Town, South Africa 2014.08.24-29
A methodology for experimental determination of stability boundaries with application to fluidized bed spray granulation
Palis, Stefan; Dreyschultze, Christian; Kienle, Achim
In: Computer aided chemical engineering - Amsterdam [u.a.] : Elsevier, Bd. 33 (2014), S. 625-630
Discrepancy-based control of a heat equation with quadratic nonlinearity
Palis, Stefan; Kienle, Achim
In: American Control Conference (ACC), 2014 - Piscataway, NJ : IEEE, S. 3359-3362 Kongress: ACC Portland, Or. 2014.06.04-06
Stability analysis of switching hyperbolic systems - the example of SMB chromatography
Bastin, Georges; Coron, Jean-Michel; d'Andréa-Novel, Brigitte; Suvarov, Paul; Wouwer, Alain Vande; Kienle, Achim
In: European Control Conference (ECC), 2014 - Piscataway, NJ : IEEE, S. 2153 - 2157 Kongress: ECC Strasbourg, France 2014.06.24-27
An efficient method for calculating the moments of multidimensional growth processes in population balance systems
Dürr, Robert; Kienle, Achim
In: The Canadian journal of chemical engineering - Ottawa, Ontario : Soc., Bd. 92 (2014), Heft 12, S. 2088-2097
Evaluation of multipoint dosing strategy in a miniaturized tubular reactor - nitration of salicylic acid
Debnath, Soujoy; Kienle, Achim; Kulkarni, Amol A.
In: Chemical engineering & technology - Weinheim : Wiley-VCH Verl.-Ges., Bd. 37 (2014), Heft 6, S. 927-937
Coupled continuous chromatography and racemization processes for the production of pure enantiomers
Swernath, Subramanian; Kaspereit, Malte; Kienle, Achim
In: Chemical engineering & technology - Weinheim : Wiley-VCH Verl.-Ges., Bd. 37 (2014), Heft 4, S. 643-651
Cycle to cycle adaptive control of simulated moving bed chromatographic separation processes
Suvarov, Paul; Kienle, Achim; Nobre, Clarisse; Weireld, Guy De; Vande Wouwer, Alain
In: Journal of process control - Amsterdam [u.a.] : Elsevier Science, Bd. 24 (2014), Heft 2, S. 357-367
Discrepancy based control of particulate processes
Palis, Stefan; Kienle, Achim
In: Journal of process control - Amsterdam [u.a.] : Elsevier Science, Bd. 24 (2014), Heft 3, S. 33-46
Development and nonlinear analysis of dynamic plant models in ProMot /Diana
Mangold, Michael; Khlopov, Dmytro; Danker, Gerrit; Palis, Stefan; Svjatnyj, Volodymyr; Kienle, Achim
In: Chemie - Ingenieur - Technik - Weinheim : Wiley-VCH Verl., Bd. 86 (2014), Heft 7, S. 1107-1116
Optimal experimental design for parameter identification and model selection
Schenkendorf, René; Mangold, Michael; Kienle, Achim
In: Magdeburg, Univ., Fak. für Elektrotechnik und Informationstechnik, Diss., 2014, XII, 159 S.
Modellbasierte Identifizierung von Interventionsstrategien für Stoffwechselnetzwerke
Hädicke, Oliver Oliver; Kienle, Achim
In: Magdeburg Univ., Fak. für Elektrotechnik und Informationstechnik, Diss., 2014, IV, 169 S.
2013
Adaptice discrepancy based control of continuous fluidized bed spray granulation with internal classification
Palis, Stefan; Bück, Andreas; Kienle, Achim
In: 9th IFAC Symposium on Nonlinear Control Systems 2013 - Elsevier, S. 400-405 Kongress: IFAC Symposium on Nonlinear Control Systems; 9 (Toulouse, France) 2013.09.04-06
Distributed modeling of human influenza a virus–host cell interactions during vaccine production
Müller, Thomas; Dürr, Robert; Isken, Britta; Schulze-Horsel, Josef; Reichl, Udo; Kienle, Achim
In: Biotechnology & bioengineering - New York, NY [u.a.] : Wiley, Bd. 110 (2013), Heft 8, S. 2252-2266
Population balance modeling of crystallization in a fluidized bed
Palis, Stefan; Binev, D.; Lorenz, H.; Seidel-Morgenstern, Andreas; Kienle, Achim
In: BIWIC 2013 - Odense : Univ. of Southern Denmark, S. 252-259 Kongress: BIWIC 20 Odense, Denmark 2013.09.18-20
Spectral properties of Bi-Langmuir isotherms
Flockerzi, D.; Kaspereit, M.; Kienle, Achim
In: Chemical engineering science - Amsterdam [u.a.] : Elsevier Science, Bd. 104 (2013), S. 957-959
H∞ loop shaping control for continuous fluidized bed spray granulation with internal product classification
Palis, Stefan; Kienle, Achim
In: Industrial & engineering chemistry research - Columbus, Ohio : American Chemical Society, Bd. 52 (2013), Heft 1, S. 408-420
Dynamics and control of coupled continuous chromatography and crystallization processes for the production of pure enantiomers
Swernath, S.; Kaspereit, M.; Kienle, Achim
In: Chemical engineering & technology - Weinheim : Wiley-VCH Verl.-Ges., Bd. 36 (2013), Heft 8, S. 1417-1429
Deterministic global optimization of multistage melt crystallization processes
Kunde, Christian; Müller, C.; Kienle, Achim
In: 2st European Congress of Applied Biotechnology and 9th European Congress of Chemical Engineering, The Hague, The Netherlands, April, 21 -25, 2013 Kongress: ECCE 9 Den Haag, The Netherlands 2013.04.21-25
An efficient method for calculating the moments of multidimensional growth processes
Dürr, Robert; Kienle, Achim
In: 5th International Conference on Population Balance Modelling - Banaglore : Indian Institute of Science . - 2013, insges. 4 S. Kongress: PBM 2013 5 Bangalore, India 2013.09.11-13
Online parameter identification for continuous fluidized bed spray granulation
Palis, Stefan; Kienle, Achim
In: 5th International Conference on Population Balance Modelling - Banaglore : Indian Institute of Science . - 2013, insges. 7 S. Kongress: PBM 2013 5 Bangalore, India 2013.09.11-13
A plug and control strategy for simulated moving bed processes - stability analysis
Suvarov, Paul; Wouwer, Alain Vande; Kienle, Achim
In: 32st Benelux Meeting on Systems and Control - UMONS . - 2013, S. 252 Kongress: Benelux Meeting on Systems and Control 32 Houffalize, Belgium 2013.03.26-28
2012
A plug and control strategy for simulated moving bed processes
Suvarov, Paul; Wouwer, Alain Vande; Kienle, Achim
In: 31st Benelux Meeting on Systems and Control - disc . - 2012, S. 343 Kongress: Benelux Meeting on Systems and Control 31 Heijden, The Netherlands 2012.03.27-29
A simple robust control for simulated moving bed chromatographic separation
Suvarov, Paul; Vande Wouwer, Alain; Kienle, Achim
In: 8th IFAC International Symposium on Advanced Control of Chemical Processes 2012 , [Online-Ausg.] - Elsevier, S. 137-142 Kongress: IFAC International Symposium on Advanced Control of Chemical Processes 8 Singapore 2012.07.10-13
Discrepancy based control of continuous fluidized bed spray granulation with internal product classification
Palis, Stefan; Kienle, Achim
In: 8th IFAC International Symposium on Advanced Control of Chemical Processes 2012 , [Online-Ausg.] - Elsevier, S. 756-761 Kongress: IFAC International Symposium on Advanced Control of Chemical Processes 8 Singapore 2012.07.10-13
Low order controller design for continuous fluidized bed spray granulation with internal product classification by robust control methods
Palis, Stefan; Bück, Andreas; Kienle, Achim
In: 7th IFAC Symposium on Robust Control Design , [Online-Ausg.] - Elsevier . - 2012, S. 701-706 Kongress: IFAC Symposium on Robust Control Design 7 Aalbourg, Denmark 2012.06.20-22
Decentralized control system design for a ternary reactive distillation with inert using mixed integer optimization
Paramasivan, Ganesh; Kienle, Achim
In: Chemical engineering & technology - Weinheim : Wiley-VCH Verl.-Ges., Bd. 35 (2012), Heft 9, S. 1609-1616
Systematic evaluation of models of different complexity for a low-density polyethylene plant
Disli, Ilknur; Kienle, Achim
In: Mathematical and computer modelling of dynamical systems - London [u.a.] : Taylor & Francis, Bd. 18 (2012), Heft 4, S. 397-412 [Special Issue: Modelling of fuel cells and chemical engineering applications]
Auto-tuning of multivariable PID controllers using iterative feedback tuning - Auto-Tuning von PID-Mehrgrößenreglern mit Hilfe von Iterative Feedback Tuning
Sommer, Steffen; Kienle, Achim
In: Automatisierungstechnik - Berlin : De Gruyter, Bd. 60 (2012), Heft 1, S. 20-27
Model-based measurement and control of fluidised bed spray granulation processes
Bück, Andreas; Tsotsas, Evangelos; Kienle, Achim; Peglow, Mirko
In: Magdeburg, Univ., Fak. für Verfahrens- und Systemtechnik, Diss., 2012, XII, 190 S.
Multiscale modeling of biopolymer production in multicellular systems
Franz, Andre; Grammel, Hardy; Rehner, Ruxandra; Paetzold, Philipp; Kienle, Achim
In: Preprints MATHMOD 2012 Vienna , [Online-Ausg.] - Vienna : ARGESIM, ARGE Simulation News, Vienna Univ. of Technology, insges. 5 S. - (ARGESIM report; 38) Kongress: MATHMOD 7 Vienna 2012.02.15-17
Distributed modeling and parameter estimation of influenza virus replication during vaccine production authors
Dürr, Robert; Müller, Thomas; Isken, Britta; Schulze-Horstel, Josef; Reichl, Udo; Kienle, Achim
In: Preprints MATHMOD 2012 Vienna , [Online-Ausg.] - Vienna : ARGESIM, ARGE Simulation News, Vienna Univ. of Technology, insges. 6 S. - (ARGESIM report; 38) Kongress: MATHMOD 7 Vienna 2012.02.15-17
Simulation and nonlinear analysis of the stagnant polymer layer in a LDPE tubular reactor
Krasnyk, Mykhaylo; Kunde, Christian; Kienle, Achim
In: Addendum to 22nd European Symposium on Computer Aided Process Engineering. - Amsterdam [u.a.] : Elsevier [u.a.], insges. 5 S., 2012Kongress: European Symposium on Computer Aided Process Engineering, ESCAPE; 22 (London) : 2012.06.17-20
Rapid selection of glucose-utilizing variants of the polyhydroxyalkanoate producer Ralstonia eutropha H16 by incubation with high substrate levels
Franz, Andre; Rehner, R.; Kienle, Achim; Grammel, H.
In: Letters in applied microbiology - Oxford : Wiley-Blackwell, Bd. 54 (2012), Heft 1, S. 45-51
Stabilization of continuous fluidized bed spray granulation with external product classification
Palis, Stefan; Kienle, Achim
In: Chemical engineering science - Génie chimique - journal internat. de génie chimique - Amsterdam : Elsevier, Bd. 70 (2012), S. 200-209
Diskrepanzbasierte Regelung der kontinuierlichen Kristallisation - Discrepancy based control of continuous crystallization
Palis, Stefan; Kienle, Achim
In: Automatisierungstechnik - Berlin : ˜deœ Gruyter, Oldenbourg, Bd. 60 (2012), Heft 3, S. 145-154
Decentralized control system design under uncertainty using mixed-integer optimization
Paramasivan, Ganesh; Kienle, Achim
In: Chemical engineering & technology - Weinheim : Wiley-VCH, Bd. 35 (2012), Heft 2, S. 261-271
Design of an integrated process of chromatography, crystallization and racemization for the resolution of 2',6'-pipecoloxylidide (PPX)
Langermann und Erlencamp, Jan von; Kaspereit, Malte; Shakeri, Mozaffar; Lorenz, Heike; Hedberg, Martin; Jones, Matthew Jonathan; Larson, Kerstin; Herschend, Björn; Arnell, Robert; Temmel, Erik; Bäckvall, Jan-E.; Kienle, Achim; Seidel-Morgenstern, Andreas
In: Organic process research & development - Washington, DC : American Chemical Society, Bd. 16 (2012), Heft 2, S. 343-352
Evaluation of competing process concepts for the production of pure enantiomers
Kaspereit, Malte; Swernath, Subramanian; Kienle, Achim
In: Organic process research & development - Washington, DC : American Chemical Society, Bd. 16 (2012), Heft 2, S. 353-363
2011
Inferential control of reactive destillation columns - an algorithmic approach
Paramasivan, Ganesh; Kienle, Achim
In: Chemical engineering & technology - Weinheim : Wiley-VCH, Bd. 34 (2011), Heft 8, S. 1235-1244
A model for the freeze start behavior of a PEM fuel cell stack
Mangold, Michael; Piewek, Silvia; Klein, Olaf; Kienle, Achim
In: Journal of fuel cell science and technology - New York, NY : ASME, Bd. 8 (2011), Heft 3, S. 031006-1-031009
Integrated simulated moving bed processes for production of single enantiomers
Palacios, J. G.; Kaspereit, Malte; Kienle, Achim
In: Chemical engineering & technology - Weinheim : Wiley-VCH, Bd. 34 (2011), Heft 5, S. 688-698
Experimental and theoretical analysis of poly(ß-hydroxybutyrate) formation and consumption in Ralstonia eutropha
Franz, André; Song, Hyun-Seob; Ramkrishna, Doraiswami; Kienle, Achim
In: Biochemical engineering journal - Amsterdam [u.a.] : Elsevier Science, Bd. 55 (2011), Heft 1, S. 49-58
Iterative feedback tuning of PID controllers for reactive distillation processes - a comparison with relay feedback tuning
Sommer, Steffen; Müller, Peter; Kienle, Achim
In: Industrial & engineering chemistry research - Washington, DC : ACS Publ., Bd. 50 (2011), Heft 16, S. 9821-9828
Experimental validation of a new integrated simulated moving bed process for the production of single enantiomers
Palacios, Javier García; Kramer, Bernhard; Kienle, Achim; Kaspereit, Malte
In: Journal of chromatography / A - Amsterdam [u.a.] : Elsevier, Bd. 1218 (2011), Heft 16, S. 2232-2239
Model-based measurement of particle size distributions in layering granulation processes
Bück, Andreas; Peglow, Mirko; Tsotsas, Evangelos; Mangold, Michael; Kienle, Achim
In: AIChE journal / American Institute of Chemical Engineers - Hoboken, NJ : Wiley-Blackwell, Bd. 57 (2011), Heft 4, S. 929-941
Towards global optimization of combined distillation-crystallization processes for the separation of closely boiling mixtures
Ballerstein, Martin; Kienle, Achim; Kunde, Christian; Michaels, Dennis; Weismantel, Robert
In: 21st European Symposium on Computer Aided Process Engineering ; Pt. A , 1. ed. - Amsterdam [u.a.] : Elsevier , 2011, S. 552-556 - (Computer-aided chemical engineering; 29) Kongress: ESCAPE 21 Chalkidiki, Greece 2011.05.29-06.01
Population balance modelling of influenza virus replication during vaccine production - influence of apoptosis
Müller, Thomas; Dürr, Robert; Isken, Britta; Schulze-Horsel, Josef; Reichl, Udo; Kienle, Achim
In: 21st European Symposium on Computer Aided Process Engineering ; Pt. B , 1. ed. - Amsterdam [u.a.] : Elsevier , 2011, S. 1336-1340 - (Computer-aided chemical engineering; 29) Kongress: ESCAPE 21 Chalkidiki, Greece 2011.05.29-06.01
2010
Decentralized control system design using mixed integer optimization
Paramasivan, Ganesh; Kienle, Achim
In: Book of abstracts and CD-ROM proceedings , 1. ed. - Lisboa : APMTAC, Associação Portuguesa de Mecânica Teórica, Aplicada e Computacional - 2010, Paper 1098, insgesamt 10 S. Kongress: EngOpt 2010 2 Lisboa, Portugal 2010.09.06-09
Model-based measurement and control of particulate processes - an application to granulation processes
Bück, Andreas; Peglow, Mirko; Tsotsas, Evangelos; Mangold, M.; Kienle, Achim
In: 19th International Congress of Chemical and Process Engineering and 7th European Congress of Chemical Engineering - Praha . - 2010, insges. 11 S. Kongress: CHISA 2008 19 Praha, Czech Republic 2010.08.28-09.01
Model-based measurement of PSDs granulation processes
Bück, Andreas; Peglow, Mirko; Tsotsas, Evangelos; Kienle, Achim
In: Abstracts and proceedings - Nürnberg . - 2010, insges. 4 S. Kongress: WCPT 6 Nürnberg 2010.04.26-29
Stabilization of a continuous fluidized bed spray granulation
Palis, Stefan; Kienle, Achim
In: 4th International Conference on Population Balance Modelling , 2010 - Berlin : Max-Planck-Institut für Dynamik komplexer technischer Systeme - 2010, S. 87-97, Art. T2-02 Kongress: PBM 2010 4 Berlin 2010.09.15-17
Temperature and humidity control of a micro PEM fuel cell stack
Kunde, Christian; Hanke-Rauschenbach, R.; Mangold, Michael; Kienle, Achim; Sundmacher, Kai; Wagner, S.; Hahn, R.
In: Fuel Cells - Weinheim : Wiley-VCH, Bd. 10 (2010), Heft 6, S. 949-959
Inline chemical process analysis in micro-plants based on thermoelectric flow and impedimetric sensors
Jacobs, Thomas; Kutzner, Christian; Kropp, Miron; Brokmann, Geert; Lang, Walter; Steinke, Arndt; Kienle, Achim; Hauptmann, Peter
In: Measurement science and technology - Bristol : IOP Publ. Ltd., Bd. 21 (2010), Heft 10, insges. 12 S.
Capillary type thermal mass flow sensors for monitoring esterification reactions in residence time micro-reactors
Jacobs, Thomas; Kienle, Achim; Hauptmann, Peter
In: Chemical engineering journal - Amsterdam : Elsevier, Bd. 160 (2010), Heft 3, S. 827-833
Reduction procedure for parametrized fluid dynamics problems based on proper orthogonal decomposition and calibration
Krasnyk, Mykhaylo; Mangold, Michael; Kienle, Achim
In: Chemical engineering science - Génie chimique - journal internat. de génie chimique - Amsterdam : Elsevier, Bd. 65 (2010), Heft 23, S. 6238-6246
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