Publikationen
2024
Circadian rhythm of brain-derived neurotrophic factor in serum and plasma
Ehrhardt, Maren; Schreiber, Stefanie; Duderstadt, Yves; Braun-Dullaeus, Rüdiger; Borucki, Katrin; Brigadski, Tanja; Müller, Notger Germar; Leßmann, Volkmar; Müller, Patrick
In: Experimental physiology - Oxford [u.a.] : Wiley-Blackwell, Bd. 109 (2024), Heft 10, S. 1755-1767
Brain-Derived neurotrophic factor and inflammatory biomarkers are unaffected by acute and chronic intermittent hypoxic-hyperoxic exposure in geriatric patients - a randomized controlled trial
Behrendt, Tom; Quisilima, Jessica Ibanez; Bielitzki, Robert; Behrens, Martin; Glazachev, Oleg S.; Brigadski, Tanja; Leßmann, Volkmar; Schega, Lutz
In: Annals of medicine - London [u.a.] : Taylor & Francis Group, Bd. 56 (2024), Heft 1, Artikel 2304650, insges. 17 S.
Distinct GABAergic modulation of timing-dependent LTP in CA1 pyramidal neurons along the longitudinal axis of the mouse hippocampus
Khodaie, Babak; Edelmann, Elke; Leßmann, Volkmar
In: iScience - Amsterdam : Elsevier, Bd. 27 (2024), Heft 3, Artikel 109320, insges. 22 S.
Controlled hypoxia acutely prevents physical inactivity-induced peripheral BDNF decline
Duderstadt, Yves; Schreiber, Stefanie; Burtscher, Johannes; Schega, Lutz; Müller, Notger Germar; Brigadski, Tanja; Braun-Dullaeus, Rüdiger C.; Leßmann, Volkmar; Müller, Patrick
In: International journal of molecular sciences - Basel : Molecular Diversity Preservation International, Bd. 25 (2024), Heft 14, Artikel 7536, insges. 14 S.
2023
Intermittent hypoxic-hyperoxic exposure prior to aerobic cycling exercise does not increase serum and plasma brain-derived neurotrophic factor levels in geriatric patients
Behrendt, Tom; Ibanez Quisilima, Jessica; Bielitzki, Robert; Behrens, Martin; Glazachev, Oleg; Brigadski, Tanja; Leßmann, Volkmar; Schega, Lutz
In: Leistung steuern. Gesundheit stärken. Entwicklung fördern. / Deutsche Vereinigung für Sportwissenschaft , 2023 - Hamburg : Feldhaus, Edition Czwalina ; Schlesinger, Torsten *1976-*, S. 185 - (Schriften der Deutschen Vereinigung für Sportwissenschaft; Band 301) [Tagung: 26. dvs-Hochschultag, Bochum, 20.-22. September 2023]
Editorial - synaptopathies : from bench to bedside
Bramham, Clive R.; Leßmann, Volkmar; Hannan, Anthony J.; Wang, Changhe; Catanese, Alberto; Böckers, Tobias M.; Zhang, Hongyu
In: Frontiers in synaptic neuroscience - Lausanne : Frontiers Research Foundation, Bd. 15 (2023), Artikel 1291163, insges. 3 S.
A delay in vesicle endocytosis by a C-terminal fragment of N-cadherin enhances Aβ synaptotoxicity
Teng, Zenghui; Kartalou, Georgia-Ioanna; Dagar, Sushma; Fraering, Patrick; Leßmann, Volkmar; Gottmann, Kurt
In: Cell death discovery - London : Nature Publishing Group, Bd. 9 (2023), Artikel 444, insges. 9 S.
Flow down gradients - the problem of pressure in this physiology core concept
Nocke, Helmut; Meyer, Frank; Leßmann, Volkmar
In: Advances in physiology education - Bethesda, Md. : Soc., Bd. 47 (2023), Heft 3, S. 461-475
Repurposing drugs against Alzheimer's disease - can the anti-multiple sclerosis drug fingolimod (FTY720) effectively tackle inflammation processes in AD?
Leßmann, Volkmar; Kartalou, Georgia-Ioanna; Endres, Thomas; Pawlitzki, Marc; Gottmann, Kurt
In: Journal of neural transmission - Wien [u.a.] : Springer, Bd. 130 (2023), Heft 8, S. 1003-1012
Regulation of low repeat spike timing-dependent LTP in CA1 of mouse hippocampal slices by GABAergic inhibition and Dopamine signaling
Khodaie, Babak; Leßmann, Volkmar
In: Magdeburg: Universitätsbibliothek, Dissertation Otto-von-Guericke-Universität Magdeburg, Fakultät für Naturwissenschaften 2023, 1 Online-Ressource (147 Seiten, 8.94 MB) [Literaturverzeichnis: Seite 127-146][Literaturverzeichnis: Seite 127-146]
Vermeidung von Misskonzeptionen in der Hämodynamik - eine grundlegende Publikation in der Zeitschrift "Advances in Physiology Education" (American Physiological Society) zur
Meyer, Frank; Leßmann, Volkmar
In: Ärzteblatt Sachsen-Anhalt - Magdeburg : Ärztekammer Sachsen-Anhalt, Bd. 34 (2023), Heft 7/8, S. 22
2022
Diverse gabaergic modulation of STDP in mouse CA1 pyramidal neurons along the longitudinal axis of the hippocampus
Khodaie, Babak; Edelmann, Elke; Leßmann, Volkmar
In: FENS Forum - FENS . - 2022, Artikel S01-390a [Forum: FENS Forum 2022, Paris, France, 09-13.07.2022]
Untersuchungen zur adulten Neuroplastizität als Auswirkung langfristiger körperlicher Aktivität im Alter
Bade, Mandy; Hökelmann, Anita; Kaufmann, Jörn; Leßmann, Volkmar; Müller, Patrick; Müller, Notger Germar
In: Zeitschrift für Gerontologie und Geriatrie - Heidelberg : Springer Medizin, Bd. 55 (2022), Heft Suppl 1, S. S107, Artikel S405-3
Calcium-permeable AMPA receptors mediate timing-dependent LTP elicited by low repeat coincident pre- and postsynaptic activity at Schaffer collateral-CA1 synapses
Cepeda-Prado, Efrain Augusto; Khodaie, Babak; Quiceno, Gloria D.; Beythien, Swantje; Edelmann, Elke; Leßmann, Volkmar
In: Cerebral cortex - Oxford : Oxford Univ. Press, Bd. 32 (2022), Heft 8, S. 1682-1703
Brain-derived neurotrophic factor expression in serotonergic neurons improves stress resilience and promotes adult hippocampal neurogenesis
Leschik, Julia; Gentile, Antonietta; Cicek, Cigdem; Péron, Sophie; Tevosian, Margaryta; Beer, Annika; Radyushkin, Konstantin; Bludau, Anna; Ebner, Karl; Neumann, Inga D.; Singewald, Nicolas; Berninger, Benedikt; Leßmann, Volkmar; Lutz, Beat
In: Progress in neurobiology - Amsterdam [u.a.]: Elsevier, 1973, Bd. 217 (2022), insges. 13 S.
Proteomics of the dentate gyrus reveals semantic dementia specific molecular pathology
Mol, Merel O.; Miedema, Suzanne S. M.; Melhem, Shamiram; Li, Ka Wan; Koopmans, Frank; Seelaar, Harro; Gottmann, Kurt; Leßmann, Volkmar; Smit, August B.; Swieten, John C. van; Rooij, Jeroen G. J. van
In: Acta Neuropathologica Communications - London : Biomed Central, Bd. 10 (2022), Artikel 190, insges. 14 S.
ProBDNF dependence of LTD and fear extinction learning in the amygdala of adult mice
Ma, Xiaoyun; Vuyyuru, Harish; Munsch, Thomas; Endres, Thomas; Leßmann, Volkmar; Meis, Susanne
In: Cerebral cortex - Oxford : Oxford Univ. Press, Bd. 32 (2022), Heft 7, S. 1350-1364
Structural and functional brain alterations in patients with myasthenia gravis
Klaus, Benita; Müller, Patrick; Wickeren, Nora; Dordevic, Milos; Schmicker, Marlen; Zdunczyk, Yael; Brigadski, Tanja; Leßmann, Volkmar; Vielhaber, Stefan; Schreiber, Stefanie; Müller, Notger Germar
In: Brain communications - [Oxford]: Oxford University Press, 2019, Bd. 4 (2022), 1, insges. 12 S.
Membrane electrical properties of mouse hippocampal CA1 pyramidal neurons during strong inputs
Bianchi, Daniela; Migliore, Rosanna; Vitale, Paola; Garad, Machhindra; Pousinha, Paula A.; Marie, Helene; Leßmann, Volkmar; Migliore, Michele
In: Biophysical journal - Cambridge, Mass.: Cell Press, 1960, Bd. 121 (2022), 4, S. 644-657
2021
Impairment of spike-timing-dependent plasticity at Schaffer collateral-CA1 synapses in adult APP/PS1 mice depends on proximity of Aβ plaques
Garad, Machhindra; Edelmann, Elke; Leßmann, Volkmar
In: International journal of molecular sciences - Basel: Molecular Diversity Preservation International, 2000, Bd. 22 (2021), 3, insges. 20 S.
BDNF haploinsufficiency induces behavioral endophenotypes of schizophrenia in male mice that are rescued by enriched environment
Harb, Mahmoud; Jagusch, Justina; Durairaja, Archana; Endres, Thomas; Leßmann, Volkmar; Fendt, Markus
In: Translational Psychiatry - London : Nature Publishing Group, Bd. 11 (2021), Artikel 233, insges. 13 S.
Long-term depression at hippocampal mossy fiber-CA3 synapses involves BDNF but is not mediated by p75NTR signaling
Garad, Machhindra; Edelmann, Elke; Leßmann, Volkmar
In: Scientific reports - [London]: Macmillan Publishers Limited, part of Springer Nature, 2011, Bd. 11 (2021), insges. 14 S.
Spike timing-dependent plasticity and basal synaptic transmission characterization at hippocampal Schaffer collateral-CA1 synapses of adult APP/PS1 Alzheimer's disease mice
Garad, Machhindra; Leßmann, Volkmar
In: Magdeburg: Universitätsbibliothek, Dissertation Otto-von-Guericke-Universität Magdeburg, Fakultät für Naturwissenschaften 2021, 1 Online-Ressource (XV, 100 Blätter, 2,91 MB) [Literaturverzeichnis: Blatt 84-98]
Die Rolle des BDNF/TrkB-Signalweges bei Lernprozessen in Wildtyp-Mäusen und einem Mausmodell des Morbus Alzheimer - [kumulative Habilitation]
Endres, Thomas; Leßmann, Volkmar; Bohlen und Halbach, Oliver; Alzheimer, Christian
In: Magdeburg: Otto-von-Guericke-Universität Magdeburg, 2020, verschiedene Seitenzählung, Illustrationen, Diagramme
2020
Anti-inflammatory treatment with FTY720 starting after onset of symptoms reverses synaptic deficits in an AD mouse model
Kartalou, Georgia-Ioanna; Salgueiro-Pereira, Ana Rita; Endres, Thomas; Lesnikova, Angelina; Casarotto, Plinio; Pousinha, Paula; Delanoe, Kevin; Edelmann, Elke; Castrén, Eero; Gottmann, Kurt; Marie, Hélène; Leßmann, Volkmar
In: International journal of molecular sciences - Basel: Molecular Diversity Preservation International, 2000, Vol. 21.2020, 23, 8957, insgesamt 23 Seiten
Cytosolic, but not matrix, calcium is essential for adjustment of mitochondrial pyruvate supply
Szibor, Marten; Gizatullina, Zemfira; Gainutdinov, Timur; Endres, Thomas; Debska-Vielhaber, Grazyna; Kunz, Matthias; Karavasili, Niki; Hallmann, Kerstin; Schreiber, Frank; Bamberger, Alexandra; Schwarzer, Michael; Doenst, Torsten; Heinze, Hans-Jochen; Leßmann, Volkmar; Vielhaber, Stefan; Kunz, Wolfram S.; Gellerich, Frank Norbert
In: The journal of biological chemistry - Bethesda, Md.: ASBMB Publications, 1905, Bd. 295 (2020), 14, S. 4383-4397
Golgi-Cox impregnation combined with fluorescence staining of amyloid plaques reveals local spine loss in an Alzheimer mouse model
Kartalou, Georgia-Ioanna; Endres, Thomas; Leßmann, Volkmar; Gottmann, Kurt
In: Journal of neuroscience methods - Amsterdam [u.a.]: Elsevier Science, 1979, Vol. 341.2020, Art.-Nr. 108797
Ketamine-induced changes in plasma brain-derived neurotrophic factor (BDNF) levels are associated with the resting-state functional connectivity of the prefrontal cortex
Woelfer, Marie; Li, Meng; Colic, Lejla; Liebe, Thomas; Di, Xin; Biswal, Bharat; Murrough, James; Leßmann, Volkmar; Brigadski, Tanja; Walter, Martin
In: The world journal of biological psychiatry - Abingdon: Taylor & Francis Group, 2000, Bd. 21.2020, 9, S. 696-710
Neurotrophin signalling in amygdala-dependent cued fear learning
Meis, Susanne; Endres, Thomas; Leßmann, Volkmar
In: Cell & tissue research - Berlin: Springer, 1924, Bd. 382 (2020), 1, S. 161-172
Reply to Rutter et al.: The roles of cytosolic and intramitochondrial Ca 2+ and the mitochondrial Ca 2+-uniporter (MCU) in the stimulation of mammalian oxidative phosphorylation. Letters to the editor
Gellerich, Frank Norbert; Szibor, Marten; Gizatullina, Zemfira; Leßmann, Volkmar; Schwarzer, Michael; Doenst, Torsten; Vielhaber, Stefan; Kunz, Wolfram S.
In: The journal of biological chemistry - Bethesda, Md.: ASBMB Publications, Bd. 295 (2020), 30, S. 10507
Editorial for the special issue neurotrophic factors
Saarma, Mart; Mobley, William; Leßmann, Volkmar
In: Cell & tissue research - Berlin: Springer, Bd. 382.2020, 1, S. 1-4
Lactate and BDNF - key mediators of exercise induced neuroplasticity?
Müller, Patrick; Duderstadt, Yves; Leßmann, Volkmar; Müller, Notger Germar
In: Journal of Clinical Medicine - Basel: MDPI, 2012, Bd. 9.2020, 4, Art.-Nr. 1136, insgesamt 15 Seiten
The physiology of regulated BDNF release
Brigadski, Tanja; Leßmann, Volkmar
In: Cell & tissue research - Berlin: Springer, 1924, Bd. 382.2020, 1, S. 15-45
2019
Impairment of spike timing-dependent plasticity in the hippocampal CA1 area of an APP/PS1 Alzheimer's disease mouse model
Garad, Machhindra; Edelmann, Elke; Leßmann, Volkmar
In: Acta physiologica / Supplement - Oxford [u.a.]: Wiley-Blackwell, 2007, Vol. 227.2019, Suppl. 719, OS 04-03, Seite 55-56
Changes in hippocampal network oscillations and single cell properties of GAD65 KO mice-a model of reduced GABAergic synthesis
Pollali, Evangelia; Caliskan, Gürsel; Munsch, Thomas; Leßmann, Volkmar; Stork, Oliver
In: 37th Göttingen Neurobiology Conference: 13th Göttingen Meeting of the German Neuroscience Society, March 20 - 23, 2019 : proceedings - Neurowissenschaftliche Gesellschaft, 2019, 2019, Artikel T23-6C - (Neuroforum, Band 25, Suppl. 1)[Konferenz: 13th Meeting of the German Neuroscience Society, Göttingen, March 20-23, 2019]
Impact of chronic BDNF depletion on GABAergic synaptic transmission in the lateral amygdala
Meis, Susanne; Endres, Thomas; Munsch, Thomas; Leßmann, Volkmar
In: International journal of molecular sciences - Basel: Molecular Diversity Preservation International, 2000, Bd.20.2019, 17, Art.-Nr. 4310, insges. 17 S.
Prominent postsynaptic and dendritic exocytosis of endogenous BDNF vesicles in BDNF-GFP knock-in mice
Leschik, Julia; Eckenstaler, Robert; Endres, Thomas; Munsch, Thomas; Edelmann, Elke; Richter, Karin; Kobler, Oliver; Fischer, Klaus-Dieter; Zuschratter, Werner; Brigadski, Tanja; Lutz, Beat; Leßmann, Volkmar
In: Molecular neurobiology - Totowa, NJ: Humana Press, Bd. 56 (2019), 10, S. 6833-6855
A kinetic model for brain-derived neurotrophic factor mediated spike timing-dependent LTP
Solinas, Sergio M. G.; Edelmann, Elke; Leßmann, Volkmar; Migliore, Michele
In: PLoS Computational Biology/ Public Library of Science - San Francisco, Calif.: Public Library of Science, 2005, Bd.15.2019, 4, Art.-Nr. e1006975, insges. 28 S.
Mitoferrin-1 is required for brain energy metabolism and hippocampus-dependent memory
Baldauf, Lisa; Endres, Thomas; Scholz, Johannes; Kirches, Elmar; Ward, Diane M.; Leßmann, Volkmar; Borucki, Katrin; Mawrin, Christian
In: Neuroscience letters - Amsterdam [u.a.]: Elsevier Science, Bd.713.2019, Art.-Nr. 134521
Periprosthetic hypoxia as consequence of TRPM7 mediated cobalt influx in osteoblasts
Römmelt, Constantin; Munsch, Thomas; Drynda, Andreas; Leßmann, Volkmar; Lohmann, Christoph H.; Bertrand, Jessica
In: Journal of biomedical materials research / B - Hoboken, NJ: Wiley, Bd. 107 (2019), 6, S. 1806-1813
Mechanisms of spike timing-dependent LTP in CA1 region of the hippocampus induced with low repeat of coincident pre- and postsynaptic spiking
Cepeda-Prado, Efrain Augusto; Leßmann, Volkmar
In: Magdeburg, Dissertation Otto-von-Guericke-Universität Magdeburg, Fakultät für Naturwissenschaften 2019, xi, 106 Seiten [Literaturverzeichnis: Seite 84-100][Literaturverzeichnis: Seite 84-100]
2018
HIPP neurons in the dentate gyrus mediate the cholinergic modulation of background context memory salience
Raza, Syed Ahsan; Albrecht, Anne; Çalişkan, Gürsel; Müller, Bettina; Demiray, Yunus Emre; Ludewig, Susann; Meis, Susanne; Faber, Nicolai; Hartig, Roland; Schraven, Burkhart; Leßmann, Volkmar; Schwegler, Herbert; Stork, Oliver
In: 11th FENS Forum of Neuroscience - FENS - 2018, Abstract 3915 [Forum: 11th FENS Forum of Neuroscience, Berlin, Germany, 7-11 July 2018]
Brain-Derived Neurotrophic Factor (BDNF) as a potential biomarker for resting-state network remodeling after ketamine infusion
Woelfer, Marie; Li, Meng; Colic, Lejla; Biswal, Bharat; Leßmann, Volkmar; Brigadski, Tanja; Walter, Martin
In: Biological psychiatry: a journal of psychiatric neuroscience ; a publication of the Society of Biological Psychiatry - Amsterdam [u.a.]: Elsevier Science, 1985, Bd. 83.2018, Suppl. 9, S140, Seite S402
Dopaminergic innervation and modulation of hippocampal networks
Edelmann, Elke; Leßmann, Volkmar
In: Cell & tissue research - Berlin: Springer, 1924, Bd. 373.2018, 3, S. 711-727
Daily intermittent normobaric hypoxia over 2 weeks reduces BDNF plasma levels in young adults - a randomized controlled feasibility study
Becke, Andreas; Müller, Patrick; Dordevic, Milos; Leßmann, Volkmar; Brigadski, Tanja; Müller, Notger Germar
In: Frontiers in physiology - Lausanne: Frontiers Research Foundation, 2007, Bd. 9.2018, Art.-Nr. 1337, insges. 7 S.
Dance training is superior to repetitive physical exercise in inducing brain plasticity in the elderly
Rehfeld, Kathrin; Lüders, Angie; Hökelmann, Anita; Leßmann, Volkmar; Kaufmann, Joern; Brigadski, Tanja; Müller, Patrick; Müller, Notger Germar
In: PLOS ONE - San Francisco, California, US : PLOS - Bd. 13.2018, 7, Art.-Nr. e0196636, insges. 15 S.
Analyzing synaptic plasticity at the single cell level with STDP
Edelmann, Elke; Leßmann, Volkmar
In: Neuroforum - Berlin: De Gruyter, 2003, Bd. 24.2018, 3, Seite A143-A150
Generation of functional cardiomyocytes from rat embryonic and induced pluripotent stem cells using feeder-free expansion and differentiation in suspension culture
Dahlmann, Julia; Awad, George; Dolny, Carsten; Weinert, Sönke; Richter, Karin; Fischer, Klaus-Dieter; Munsch, Thomas; Leßmann, Volkmar; Volleth, Marianne; Zenker, Martin; Chen, Yaoyao; Merkl, Claudia; Schnieke, Angelika; Baraki, Hassina; Kutschka, Ingo; Kensah, George
In: PLOS ONE - San Francisco, California, US: PLOS, 2006, Bd. 13.2018, 3, Art.-Nr. e0192652, insges. 22 S.
The relation between long-term synaptic plasticity at glutamatergic synapses in the amygdala and fear learning in adult heterozygous BDNF-knockout mice
Meis, Susanne; Endres, Thomas; Munsch, Thomas; Leßmann, Volkmar
In: Cerebral cortex - Oxford: Oxford Univ. Press, 1991, Bd. 28.2018, 4, S. 1195-1208
Dorsal tegmental dopamine neurons gate associative learning of fear
Groessl, Florian; Munsch, Thomas; Meis, Susanne; Griessner, Johannes; Kaczanowska, Joanna; Pliota, Pinelopi; Kargl, Dominic; Badurek, Sylvia; Kraitsy, Klaus; Rassoulpour, Arash; Zuber, Johannes Ekkehart; Leßmann, Volkmar; Haubensak, Wulf
In: Nature neuroscience - New York, NY: Nature America, 1998, Bd. 21.2018, 7, S. 952-962
Memory enhancement by ferulic acid ester across species
Michels, Birgit; Zwaka, Hanna; Bartels, Ruth; Lushchak, Oleh; Franke, Katrin; Endres, Thomas; Fendt, Markus; Song, Inseon; Bakr, May; Budragchaa, Tuvshinjargal; Westermann, Bernhard; Mishra, Dushyant; Eschbach, Claire; Schreyer, Stefanie; Lingnau, Annika; Vahl, Caroline; Hilker, Marike; Menzel, Randolf; Kähne, Thilo; Leßmann, Volkmar; Dityatev, Alexander; Wessjohann, Ludger; Gerber, Bertram
In: Science advances - Washington, DC [u.a.]: Assoc., 2015, Bd. 4.2018, 10, Art.-Nr. eaat6994, insges. 18 S.
Oxidative stress in drug-naive first episode patients with schizophrenia and major depression - effects of disease acuity and potential confounders
Jordan, Wolfgang; Dobrowolny, Henrik; Bahn, Sabine; Bernstein, Hans-Gert; Brigadski, Tanja; Frodl, Thomas; Isermann, Berend; Leßmann, Volkmar; Pilz, Jürgen; Rodenbeck, Andrea; Schiltz, Kolja; Schwedhelm, Edzard; Tumani, Hayrettin; Wiltfang, Jens; Guest, Paul C.; Steiner, Johann
In: European archives of psychiatry and clinical neuroscience - Darmstadt : Steinkopff, Bd. 268 (2018), Heft 2, S. 129-143
Presynaptic regulation of tonic inhibition by neuromodulatory transmitters in the basal amygdala
Meis, Susanne; Endres, Thomas; Munsch, Thomas; Leßmann, Volkmar
In: Molecular neurobiology - Totowa, NJ: Humana Press, 1987, Bd. 55.2018, 11, S. 8509-8521
2017
Wirkung eines fünfwöchigen Kraftausdauertrainings unter normobarer Hypoxie auf den Serum-BDNF bei jungen vs. älteren Menschen
Törpel, Alexander; Brigadski, Tanja; Leßmann, Volkmar; Schega, Lutz
In: Innovation & Technologie im Sport / Deutsche Vereinigung für Sportwissenschaft , 2017 - Hamburg : Feldhaus, Edition Czwalina, S. 174 - (Schriften der Deutschen Vereinigung für Sportwissenschaft; 265)
Evolution of neuroplasticity in response to physical activity in old age - the case for dancing
Müller, Patrick; Rehfeld, Kathrin; Schmicker, Marlen; Hökelmann, Anita; Dordevic, Milos; Leßmann, Volkmar; Brigadski, Tanja; Kaufmann, Jörn; Müller, Notger Germar
In: Frontiers in aging neuroscience - Lausanne: Frontiers Research Foundation, 2010, Bd. 9.2017, Art.-Nr. 56, insges. 8 S.
HIPP neurons in the dentate gyrus mediate the cholinergic modulation of background context memory salience
Raza, Ahsan Syed; Albrecht, Anne; Çalişkan, Gürsel; Müller, Bettina; Demiray, Yunus Emre; Ludewig, Susann; Meis, Susanne; Faber, Nicolai; Hartig, Roland; Schraven, Burkhart; Leßmann, Volkmar; Schwegler, Herbert; Stork, Oliver
In: Nature Communications - [London] : Nature Publishing Group UK - Vol. 8.2017, Art. 189, insgesamt 15 S.
Coexistence of multiple types of synaptic plasticity in individual hippocampal CA1 pyramidal neurons
Edelmann, Elke; Cepeda-Prado, Efrain Augusto; Leßmann, Volkmar
In: Frontiers in synaptic neuroscience - Lausanne: Frontiers Research Foundation, 2009, Bd. 9.2017, Art.-Nr. 7, insges. 15 S.
Laterale Diffusion Spannungs und/oder Liganden gesteuerter Ionenkanäle als Variable neuronaler Plastizität
Heine, Martin; Leßmann, Volkmar
In: Magdeburg, 2017, 1 Band (verschiedene Seitenzählungen), Illustrationen, Diagramme, 30 cm
2016
CAPS1 effects on intragranular pH and regulation of BDNF release from secretory granules in hippocampal neurons
Eckenstaler, Robert; Leßmann, Volkmar; Brigadski, Tanja
In: Journal of cell science - Cambridge: Company of Biologists Limited, 1853, Bd. 129.2016, 7, S. 1378-1390
Amyloid-beta induced changes in vesicular transport of BDNF in hippocampal neurons
Seifert, Bianca; Eckenstaler, Robert; Rönicke, Raik; Leschik, Julia; Lutz, Beat; Reymann, Klaus; Leßmann, Volkmar; Brigadski, Tanja
In: Neural plasticity - New York, NY: Hindawi, 1998, (2016), Article ID 4145708, insges. 15 S.
Relationships of peripheral IGF-1, VEGF and BDNF levels to exercise-related changes in memory, hippocampal perfusion and volumes in older adults
Maass, Anne; Düzel, Sandra; Brigadski, Tanja; Görke, Monique; Becke, Andreas; Sobieray, Uwe; Neumann, Katja; Lövdén, Martin; Lindenberger, Ulman; Bäckman, Lars; Braun-Dullaeus, Rüdiger; Ahrens, Dörte; Heinze, Hans-Jochen; Müller, Notger Germar; Leßmann, Volkmar; Sendtner, Michael; Düzel, Emrah
In: NeuroImage - Orlando, Fla. : Academic Press, Bd. 131 (2016), S. 142-154
Effect of intermittent normobaric hypoxia on aerobic capacity and cognitive function in older people
Schega, Lutz; Peter, Beate; Brigadski, Tanja; Leßmann, Volkmar; Isermann, Berend; Hamacher, Dennis; Törpel, Alexander
In: Journal of science and medicine in sport - Amsterdam [u.a.] : Elsevier, Bd. 19 (2016), Heft 11, S. 941-945
Regulation der Kalzium-abhängigen Ausschüttung von BDNF aus hippokampalen Neuronen durch CAPS1
Eckenstaler, Robert; Leßmann, Volkmar
In: Magdeburg, 2016, 133 Seiten, Illustrationen, Diagramme, 30 cm[Literaturverzeichnis: Seite 124-133]
2015
Opposing effects of cAMP-effectors PKA and Epac on activity-dependent BDNF secretion in dissociated hippocampal neurons
Heyne, Jan-Hendrik; Lichtenecker, Petra; Brigadski, Tanja; Leßmann, Volkmar
In: Acta physiologica / Supplement - Oxford [u.a.]: Wiley-Blackwell, 2007, Vol. 213.2015, Suppl. 699, P224, S. 162
Coexistence of different forms of timing-dependent LTP at hippocampal CA3-CA1 synapses
Edelmann, Elke; Cepeda-Prado, Efrain Augusto; Leßmann, Volkmar
In: Acta physiologica / Supplement - Oxford [u.a.]: Wiley-Blackwell, 2007, Vol. 213.2015, Suppl. 699, OS2-03, S. 42-43
Interaction between amyloid-[beta] peptide and BDNF signalling in hippocampal neurogenesis
Dobrota, Dijana; Leßmann, Volkmar; Brigadski, Tanja
In: Acta physiologica / Supplement - Oxford [u.a.]: Wiley-Blackwell, 2007, Vol. 213.2015, Suppl. 699, P236, S. 167
Systemic hypoxia affects attenuated expression of erythropoietin in old age
Törpel, Alexander; Peter, Beate; Leßmann, Volkmar; Brigadski, Tanja; Schega, Lutz
In: Acta physiologica / Supplement - Oxford [u.a.]: Wiley-Blackwell, 2007, Vol. 213.2015, Suppl. 699, S. 194[Annual Meeting of the German Physiological Society ; 94 (Magdeburg) : 2015.03.05-07]
Amyloid-beta-induced changes in vesicular transport of BDNF in hippocampal neurons
Seifert, Bianca; Eckenstaler, Robert; Rönicke, Raik; Leschik, Julia; Lutz, Beat; Reymann, Klaus; Leßmann, Volkmar; Brigadski, Tanja
In: Acta physiologica. Supplement - Oxford [u.a.] : Wiley-Blackwell - Vol. 213.2015, Suppl. 699, P221, S. 161
Fear and fear extinction learning in APP/PS1 mice
Endres, Thomas; Hölzl, Gloria; Edelmann, Elke; Leßmann, Volkmar
In: Acta physiologica / Supplement - Oxford [u.a.]: Wiley-Blackwell, 2007, Vol. 213.2015, Suppl. 699, P132, S. 122
Long-term plasticity and fear learning in adult heterozygous BDNF knockout mice
Meis, Susanne; Endres, Thomas; Munsch, Thomas; Leßmann, Volkmar
In: Acta physiologica / Supplement - Oxford [u.a.]: Wiley-Blackwell, 2007, Vol. 213.2015, Suppl. 699, P138, S. 125
The second messenger cAMP modulates the secretion of BDNF from dissociated hippocampal neurons
Lichtenecker, Petra; Brigadski, Tanja; Leßmann, Volkmar
In: Acta physiologica / Supplement - Oxford [u.a.]: Wiley-Blackwell, 2007, Vol. 213.2015, Suppl. 699, P228, S. 163-164
Increase of BDNF in response to normobaric hypoxia in humans
Törpel, Alexander; Peter, Beate; Leßmann, Volkmar; Brigadski, Tanja; Schega, Lutz
In: AHA 2015: the book of abstracts Active Healthy Aging Sports Science and Neuroscience International Conference / ed. by Tariq Ali Gujar ...: the book of abstracts Active Healthy Aging Sports Science and Neuroscience International Conference - Magdeburg, 2015 . - 2015, S. 110
CAPS1 critically regulates BDNF release and intragranular pH of secretory granules
Eckenstaler, Robert; Leßmann, Volkmar; Brigadski, Tanja
In: Acta physiologica / Supplement - Oxford [u.a.]: Wiley-Blackwell, 2007, Vol. 213.2015, Suppl. 699, P231, S. 164-165
Influence of number of spike pairings on induction mechanisms in Spike timing-dependent plasticity
Cepeda-Prado, Efrain Augusto; Leßmann, Volkmar; Edelmann, Elke
In: Acta physiologica / Supplement - Oxford [u.a.]: Wiley-Blackwell, 2007, Vol. 213.2015, Suppl. 699, P101, S. 108
Effect of intermittent normobaric hypoxia on the health status in older people
Schega, Lutz; Peter, Beate; Leßmann, Volkmar; Törpel, Alexander; Brigadski, Tanja
In: Journal of rehabilitation medicine: official journal of the UEMS European Board of Physical and Rehabilitation Medicine - Uppsala: Foundation for Rehabilitation Information, 2001, Bd. 47.2015, Suppl. 54, Abs. PA795, S. 319Kongress: World Congress of International Society of Physical and Rehabilitation Medicine (Berlin : 2015.06.19-23)
Overexpression of BDNF and full-length TrkB receptor ameliorate striatal neural survival in Huntington's disease
Silva, Ana; Naia, Luana; Dominguez, Alejandro; Ribeiro, Márcio; Rodrigues, Joana; Vieira, Otília V.; Leßmann, Volkmar; Rego, Ana Cristina
In: Neurodegenerative diseases - Basel: Karger, Bd. 15 (2015), 4, S. 207-218
Chronic BDNF deficiency leads to an age-dependent impairment in spatial learning
Petzold, Anne; Psotta, Laura; Brigadski, Tanja; Endres, Thomas; Lessmann, Volkmar
In: Neurobiology of learning and memory. - Orlando, Fla : Academic Press, Bd. 120.2015, S. 52-60
Theta burst firing recruits BDNF release and signaling in postsynaptic CA1 neurons in spike-timing-dependent LTP
Edelmann, Elke; Cepeda-Prado, Efrain Augusto; Franck, Martin; Lichtenecker, Petra; Brigadski, Tanja; Leßmann, Volkmar
In: Neuron - [Cambridge, Mass.]: Cell Press, Bd. 86 (2015), 4, S. 1041-1054
Chronic BDNF deficiency leads to an age-dependent impairment in spatial learning
Petzold, Anne; Psotta, Laura; Brigadski, Tanja; Endres, Thomas; Leßmann, Volkmar
In: Neurobiology of learning and memory - Orlando, Fla.: Academic Press, Bd. 120 (2015), S. 52-60
Impact of an additional chronic BDNF reduction on learning performance in an Alzheimer mouse model
Psotta, Laura; Rockahr, Carolin; Gruß, Michael; Kirches, Elmar; Braun, Anna Katharina; Leßmann, Volkmar; Bock, Jörg; Endres, Thomas
In: Frontiers in behavioral neuroscience - Lausanne: Frontiers Research Foundation, Bd. 9.2015, Art.-Nr.58, insges. 10 S.
Einfluss der chronischen Reduktion des endogenen Neutrophins BDNF auf kognitive Prozesse im APP/PS1 Alzheimer-Mausmodell
Psotta, Laura; Leßmann, Volkmar
In: Magdeburg, Univ., Fak. für Naturwiss., Diss., 2015, 2014, 137 S., graph. Darst.
Anti- und proarrhythmische Wirkung, Verträglichkeit und Sicherheit von Dronedaron (SSR149744C) bei Patienten mit Vorhofflimmern - [kumulative Habilitation]
Said, Samir; Leßmann, Volkmar
In: Magdeburg, Univ., Med. Fak., Habil.-Schr., 2015, Getr. Zählung, Ill., graph. Darst.
2014
Single-cell juxtacellular recording and transfection technique
Brigadski, Tanja; Daniel, Julia; Leßmann, Volkmar
In: Acta physiologica / Supplement - Oxford [u.a.]: Wiley-Blackwell, 2007, Bd. 210.2014, Suppl.695, Abs. P262, S. 181-182
Recruitment of BDNF/TrkB signaling in hippocampal mossy fiber LTP depends on stimulation frequency used for LTP induction
Edelmann, Elke; Jahn, Angela; Schildt, Sandra; Leßmann, Volkmar
In: Acta physiologica / Supplement - Oxford [u.a.]: Wiley-Blackwell, 2007, Bd. 210.2014, Suppl.695, P074, S. 112
Low-repeat STDP paradigms induce dopamine sensitive plasticity in acute hippocampal slices
Cepeda, Efrain; Leßmann, Volkmar; Edelmann, Elke
In: Acta physiologica / Supplement - Oxford [u.a.]: Wiley-Blackwell, 2007, Bd. 210.2014, Suppl.695, P252, S. 178
Influence of the second messenger cAMP on the activity-induced secretion of BDNF in dissociated hippocampal neurons
Lichtenecker, Petra; Brigadski, Tanja; Leßmann, Volkmar
In: Acta physiologica / Supplement - Oxford [u.a.]: Wiley-Blackwell, 2007, Bd. 210.2014, Suppl. 695, OS7-06, S. 70
Molecular regulation of Ca2+-dependent neurotrophin secretion in hippocampal neurons by CAPS1
Eckenstaler, Robert; Munsch, Thomas; Brigadski, Tanja; Leßmann, Volkmar
In: Acta physiologica / Supplement - Oxford [u.a.]: Wiley-Blackwell, 2007, Bd. 210.2014, Suppl.695, P068, S. 110
BDNF-induced nitric oxide signals in cultured rat hippocampal neurons - time course, mechanism of generation, and effect on neurotrophin secretion
Kolarow, Richard; Kuhlmann, Christoph R. W.; Munsch, Thomas; Zehendner, Christoph Michael; Brigadski, Tanja; Luhmann, Heiko; Leßmann, Volkmar
In: Frontiers in cellular neuroscience - Lausanne: Frontiers Research Foundation, 2007, Bd. 8.2014, Art.-Nr. 323, insges. 12 S.
BDNF - a regulator of learning and memory processes with clinical potential
Brigadski, Tanja; Leßmann, Volkmar
In: e-Neuroforum - Heidelberg : Spektrum Akademischer Verlag, Bd. 5 (2014), Heft 1, S. 1-11
Pre- and postsynaptic twists in BDNF secretion and action in synaptic plasticity
Edelmann, Elke; Leßmann, Volkmar; Brigadski, Tanja
In: Neuropharmacology - Amsterdam [u.a.]: Elsevier Science, Bd. 76, Part C.2014, S. 610-627
BDNF - ein Regulator von Lern- und Gedächtnisprozessen mit klinischem Potenzial
Brigadski, Tanja; Leßmann, Volkmar
In: Neuroforum - Berlin : De Gruyter, Bd. 20 (2014), Heft 1, S. 166-177
Aspekte der Gefäßphysiologie im klinisch-operativen Alltag - Grundbegriffe der Gefäßmechanik - Aspects of vascular physiology in clinical and vascular surgical practice - basic principles of vascular mechanics
Nocke, Helmut; Meyer, Frank; Leßmann, Volkmar
In: Zentralblatt für Chirurgie - Stuttgart [u.a.] : Thieme, Bd. 139 (2014), Heft 5, S. 499-507
Einzelzelltransfektion in organotypischen Schnittkulturen und die Bedeutung von BDNF bei Prozessen der synaptischen Transmission und Plastizität
Daniel, Julia; Leßmann, Volkmar
In: Magdeburg, Univ., Fak. für Naturwiss., Diss., 2014, V, 94 Bl., Bl. VII - XI, graph. Darst.
2013
Impaired fear extinction learning in adult heterozygous BDNF knock-out mice
Psotta, Laura; Leßmann, Volkmar; Endres, Thomas
In: Neurobiology of learning and memory: an interdisciplinary journal - Amsterdam: Elsevier, Bd. 103 (2013), S. 34-38
Acute and chronic interference with BDNF/TrkB-signaling impair LTP selectively at mossy fiber synapses in the CA3 region of mouse hippocampus
Schildt, Sandra; Endres, Thomas; Leßmann, Volkmar; Edelmann, Elke
In: Neuropharmacology - Amsterdam [u.a.]: Elsevier Science, Bd. 71 (2013), S. 247-254
BDNF-dependent consolidation of fear memories in the perirhinal cortex
Schulz-Klaus, Brigitte; Leßmann, Volkmar; Endres, Thomas
In: Frontiers in behavioral neuroscience - Lausanne: Frontiers Research Foundation, 2007, Bd. 7.2013, Art.-Nr. 205, insges. 7 S.
Single-cell juxtacellular transfection and recording technique
Daniel, Julia; Polder, Hans Reiner; Leßmann, Volkmar; Brigadski, Tanja
In: Pflügers Archiv - Berlin: Springer, 1868, Bd. 465.2013, 11, S. 1637-1649
Embryonic stem cells stably expressing BDNFGFP exhibit a BDNF-release-dependent enhancement of neuronal differentiation
Leschik, Julia; Eckenstaler, Robert; Nieweg, Katja; Lichtenecker, Petra; Brigadski, Tanja; Gottmann, Kurt; Leßmann, Volkmar; Lutz, Beat
In: Journal of cell science - Cambridge: Company of Biologists Limited, 1853, Bd. 126.2013, 21, S. 5062-5073
Dopamine regulates intrinsic excitability thereby gating successful induction of spike timing-dependent plasticity in CA1 of the hippocampus
Edelmann, Elke; Leßmann, Volkmar
In: Frontiers in neuroscience - Lausanne: Frontiers Research Foundation, 2007, Vol. 7.2013, Art. 25, insgesamt 11 S.
2012
Postsynaptic BDNF signalling regulates long-term potentiation at thalamo-amygdala afferents
Meis, Susanne; Endres, Thomas; Leßmann, Volkmar
In: The journal of physiology - Oxford: Blackwell, 1878, Bd. 590.2012, 1, S. 193-208
Impaired transmission at corticothalamic excitatory inputs and intrathalamic GABAergic synapses in the ventrobasal thalamus of heterozygous BDNF knockout mice
Laudes, Thomas; Meis, Susanne; Munsch, Thomas; Leßmann, Volkmar
In: Neuroscience / IBRO, International Brain Research Organization - Amsterdam ˜[u.a.]œ: Elsevier, 1976, Bd. 222.2012, S. 215-227
Age-dependent deficits in fear learning in heterozygous BDNF knock-out mice
Endres, Thomas; Leßmann, Volkmar
In: Learning & memory - Plainview, NY: Cold Spring Harbor Laboratory Press, 1994, Bd. 19.2012, 12, S. 561-570
2011
Dopamine modulates spike timing-dependent plasticity and action potential properties in CA1 pyramidal neurons of acute rat hippocampal slices
Edelmann, Elke; Leßmann, Volkmar
In: Frontiers in synaptic neuroscience - Lausanne: Frontiers Research Foundation, 2009, Bd. 3.2011, Artikel 6, insges. 16 S.
The expression mechanism of the residual LTP in the CA1 region of BDNF k.o. mice is insensitive to NO synthase inhibition
Leßmann, Volkmar; Stroh-Kaffei, Sigrid; Steinbrecher, Violetta; Edelmann, Elke; Brigadski, Tanja; Kilb, Werner; Luhmann, Heiko J.
In: Brain research: internat. multidisciplinary journal devoted to fundamental research in the brain sciences / ed. board K. Akert [u.a.]: internat. multidisciplinary journal devoted to fundamental research in the brain sciences - Amsterdam: Elsevier, 1966, Bd. 1391.2011, S. 14-23
2010
Essential cooperation of N-cadherin and neuroligin-1 in the transsynaptic control of vesicle accumulation
Stan, Adriana; Pielarski, Kim N.; Brigadski, Tanja; Wittenmayer, Nina; Fedorchenko, Olga; Gohla, Antje; Lessmann, Volkmar; Dresbach, Thomas; Gottmann, Kurt
In: Proceedings of the National Academy of Sciences of the United States of America - Washington, DC : NAS, Bd. 107 (2010), Heft 24, S. 11116-11121
2009
Cytotoxic CD8+ T cell-neuron interactions: perforin-dependent electrical silencing precedes but is not causally linked to neuronal cell death
Meuth, Sven; Herrmann, Alexander M.; Simon, Ole J.; Siffrin, Volker; Melzer, Nico; Bittner, Stefan; Meuth, Patrick; Langer, Harald F.; Hallermann, Stefan; Boldakowa, Nadia; Herz, Josephine; Munsch, Thomas; Landgraf, Peter; Aktaş, Orhan; Heckmann, Manfred; Lessmann, Volkmar; Budde, Thomas; Kieseier, Bernd C.; Zipp, Frauke; Wiendl, Heinz
In: The journal of neuroscience: the official journal of the Society for Neuroscience - Washington, DC: Society for Neuroscience, SfN, 1981, Bd. 29.2009, 49, S. 15397-15409
Imaging of evoked dense-core-vesicle exocytosis in hippocampal neurons reveals long latencies and kiss-and-run fusion events
Xia, Xiaofeng; Lessmann, Volkmar; Martin, Thomas F. J.
In: Journal of cell science / publ. for the Company of Biologists Limited - Cambridge: Company of Biologists Limited, 1966, Bd. 122.2009, 1, S. 75-82
A protein interaction node at the neurotransmitter release site: domains of Aczonin/Piccolo, Bassoon, CAST, and Rim converge on the N-terminal domain of Munc13-1
Wang, Xiaolu; Hu, Bin; Zieba, Agata; Neumann, Nicole G.; Kasper-Sonnenberg, Monika; Honsbein, Annegret; Hultqvist, Greta; Conze, Tim; Witt, Wolfgang; Limbach, Christoph; Geitmann, Matthis; Danielson, Helena; Kolarow, Richard; Niemann, Gesa; Lessmann, Volkmar; Kilimann, Manfred W.
In: The journal of neuroscience: the official journal of the Society for Neuroscience - Washington, DC: Society for Neuroscience, SfN, 1981, Bd. 29.2009, 40, S. 12584-12596
Mechanisms of C-reactive protein-induced blood-brain barrier disruption
Kuhlmann, Christoph R. W.; Librizzi, Laura; Closhen, Dorothea; Pflanzner, Thorsten; Leßmann, Volkmar; Pietrzik, Claus Ulrich; Curtis, Marco; Luhmann, Heiko J.
In: Stroke: a journal of cerebral circulation / American Heart Association: a journal of cerebral circulation - Baltimore, MD: Lippincott Williams & Wilkins, 1970, Bd. 40.2009, 4, S. 1458-1466
Cellular mechanisms of subplate-driven and cholinergic input-dependent network activity in the neonatal rat somatosensory cortex
Hanganu, Ileana L.; Okabe, Akihito; Lessmann, Volkmar; Luhmann, Heiko J.
In: Cerebral cortex - New York, NY: Oxford Univ. Press, 1991, Bd. 19.2009, 1, S. 89-105
A population of serum deprivation-induced bone marrow stem cells (SD-BMSC) expresses marker typical for embryonic and neural stem cells
Sauerzweig, Steven; Munsch, Thomas; Leßmann, Volkmar; Reymann, Klaus G.; Braun, Holger
In: Experimental cell research - San Diego, Calif. : Elsevier, Bd. 315 (2009), Heft 1, S. 50-66
Mechanisms, locations, and kinetics of synaptic BDNF secretion: an update
Leßmann, Volkmar; Brigadski, Tanja
In: Neuroscience research - Shannon : Elsevier, Bd. 65 (2009), Heft 1, S. 11-22
Brain-derived neurotrophic factor signaling in the HVC is required for testosterone-induced song of female canaries
Hartog, Tessa E.; Dittrich, Falk; Pieneman, Anton W.; Jansen, René F.; Frankl-Vilches, Carolina; Lessmann, Volkmar; Lilliehook, Christina; Goldman, Steven A.; Gahr, Manfred
In: The journal of neuroscience: the official journal of the Society for Neuroscience - Washington, DC: Society for Neuroscience, SfN, 1981, Bd. 29.2009, 49, S. 15511-15519
Activity-dependent dendritic release of BDNF and biological consequences
Kuczewski, Nicola; Porcher, Christophe; Leßmann, Volkmar; Medina, Igor; Gaiarsa, Jean-Luc
In: Molecular neurobiology - New York, NY : Humana Press, a part of Springer Science + Business Media, Bd. 39 (2009), Heft 1, S. 37-49
BDNF signaling in the formation, maturation and plasticity of glutamatergic and GABAergic synapses
Gottmann, Kurt; Mittmann, Thomas; Leßmann, Volkmar
In: Experimental brain research - Berlin : Springer, Bd. 199 (2009), Heft 3/4, S. 203-234
2008
Back-propagating action potential - a key contributor in activity-dependent dendritic release of BDNF
Kuczewski, Nicola; Porcher, Christophe; Leßmann, Volkmar; Medina, Igor; Gaiarsa, Jean-Luc
In: Communicative & integrative biology - Austin, Tex. : Landes Bioscience, Bd. 1 (2008), Heft 2, S. 153-155
Backpropagating action potentials trigger dendritic release of BDNF during spontaneous network activity
Kuczewski, Nicola; Porcher, Christophe; Ferrand, Nadine; Fiorentino, Hervé; Pellegrino, Christophe; Kolarow, Richard; Lessmann, Volkmar; Medina, Igor; Gaiarsa, Jean-Luc
In: The journal of neuroscience: the official journal of the Society for Neuroscience - Washington, DC: Society for Neuroscience, SfN, 1981, Bd. 28.2008, 27, S. 7013-7023
Fluvastatin prevents glutamate-induced blood-brain-barrier disruption in vitro
Kuhlmann, Christoph R. W.; Gerigk, Marlis; Bender, Bianca; Closhen, Dorothea; Leßmann, Volkmar; Luhmann, Heiko J.
In: Life sciences - Amsterdam [u.a.] : Elsevier, Bd. 82 (2008), Heft 25/26, S. 1281-1287
Activity-dependent regulation of neuronal apoptosis in neonatal mouse cerebral cortex
Heck, Nicolas; Golbs, Antje; Riedemann, Therese; Sun, Jyh-Jang; Leßmann, Volkmar; Luhmann, Heiko J.
In: Cerebral cortex - New York, NY : Oxford Univ. Press, Bd. 18 (2008), Heft 6, S. 1335-1349
Impaired GABAergic inhibition in the visual cortex of brain-derived neurotrophic factor heterozygous knockout mice
Abidin, Ismail; Eysel, Ulf T.; Leßmann, Volkmar; Mittmann, Thomas
In: The journal of physiology - Oxford : Blackwell, Bd. 586 (2008), Heft 7, S. 1885-1901
The functional role of the second NPXY motif of the LRP1 [beta]-chain in tissue-type plasminogen activator-mediated activation of N-methyl-D-aspartate receptors
Martin, Anne M.; Kuhlmann, Christoph; Trossbach, Svenja; Jaeger, Sebastian; Waldron, Elaine; Roebroek, Anton; Luhmann, Heiko J.; Laatsch, Alexander; Weggen, Sascha; Leßmann, Volkmar; Pietrzik, Claus Ulrich
In: The journal of biological chemistry - Bethesda, Md. : ASBMB, Bd. 283 (2008), Heft 18, S. 12004-12013
2007
Presynaptic plasticity in an immature neocortical network requires NMDA receptor activation and BDNF release.
Walz, Corinna; Jüngling, Kay; Lessmann, Volkmar; Gottmann, Kurt
In: Journal of neurophysiology, Vol. 96, 2007, S. 3512-6, ISSN Print0022-3077, 10.1152/jn.00018.2006
Reduced presynaptic efficiency of excitatory synaptic transmission impairs LTP in the visual cortex of BDNF-heterozygous mice.
Abidin, Ismail; Köhler, Torben; Weiler, Elke; Zoidl, Georg; Eysel, Ulf T; Lessmann, Volkmar; Mittmann, Thomas
In: The European journal of neuroscience, Vol. 24, 2007, S. 3519-31, ISSN Print0953-816X, 10.1111/j.1460-9568.2006.05242.x
Inhibition of the myosin light chain kinase prevents hypoxia-induced blood-brain barrier disruption.
Kuhlmann, Christoph R W; Tamaki, Ryo; Gamerdinger, Martin; Lessmann, Volkmar; Behl, Christian; Kempski, Oliver S; Luhmann, Heiko J
In: Journal of neurochemistry, Vol. 102, 2007, S. 501-7, ISSN Print0022-3042, 10.1111/j.1471-4159.2007.04506.x
Postsynaptic secretion of BDNF and NT-3 from hippocampal neurons depends on calcium-calmodulin kinase II signaling and proceeds via delayed fusion pore opening
Kolarow, Richard; Brigadski, Tanja; Lessmann, Volkmar
In: The journal of neuroscience: the official journal of the Society for Neuroscience - Washington, DC: Society for Neuroscience, SfN, 1981, Bd. 27.2007, 39, S. 10350-10364
2006
Differential vesicular targeting and time course of synaptic secretion of the mammalian neurotrophins.
Brigadski, Tanja; Hartmann, Matthias; Lessmann, Volkmar
In: The Journal of neuroscience : the official journal of the Society for Neuroscience, Vol. 25, 2006, S. 7601-14, ISSN 1529-2401, 10.1523/JNEUROSCI.1776-05.2005
Fluvastatin stabilizes the blood-brain barrier in vitro by nitric oxide-dependent dephosphorylation of myosin light chains.
Kuhlmann, Christoph R W; Lessmann, Volkmar; Luhmann, Heiko J
In: Neuropharmacology, Vol. 51, 2006, S. 907-13, ISSN Print0028-3908, 10.1016/j.neuropharm.2006.06.004
N-cadherin transsynaptically regulates short-term plasticity at glutamatergic synapses in embryonic stem cell-derived neurons.
Jüngling, Kay; Eulenburg, Volker; Moore, Robert; Kemler, Rolf; Lessmann, Volkmar; Gottmann, Kurt
In: The Journal of neuroscience : the official journal of the Society for Neuroscience, Vol. 26, 2006, S. 6968-78, ISSN 1529-2401, 10.1523/JNEUROSCI.1013-06.2006
2004
Huntingtin controls neurotrophic support and survival of neurons by enhancing BDNF vesicular transport along microtubules.
Gauthier, Laurent R; Charrin, Bénédicte C; Borrell-Pagès, Maria; Dompierre, Jim P; Rangone, Hélène; Cordelières, Fabrice P; De Mey, Jan; MacDonald, Marcy E; Lessmann, Volkmar; Humbert, Sandrine; Saudou, Frédéric
In: Cell, Vol. 118, 2004, S. 127-38, ISSN Print0092-8674, 10.1016/j.cell.2004.06.018
Truncated TrkB receptor-induced outgrowth of dendritic filopodia involves the p75 neurotrophin receptor.
Hartmann, Matthias; Brigadski, Tanja; Erdmann, Kai S; Holtmann, Bettina; Sendtner, Michael; Narz, Frank; Lessmann, Volkmar
In: Journal of cell science, Vol. 117, 2004, S. 5803-14, ISSN Print0021-9533, 10.1242/jcs.01511
2003
Neurotrophin secretion: current facts and future prospects.
Lessmann, Volkmar; Gottmann, Kurt; Malcangio, Marzia
In: Progress in neurobiology, Vol. 69, 2003, S. 341-74, ISSN Print0301-0082
Developmental maturation of synaptic vesicle cycling as a distinctive feature of central glutamatergic synapses.
Mohrmann, R; Lessmann, V; Gottmann, K
In: Neuroscience, Vol. 117, 2003, S. 7-18, ISSN Print0306-4522
A common thread for pain and memory synapses? Brain-derived neurotrophic factor and trkB receptors.
Malcangio, Marzia; Lessmann, Volkmar
In: Trends in pharmacological sciences, Vol. 24, 2003, S. 116-21, ISSN Print0165-6147, 10.1016/S0165-6147(03)00025-7
2002
Reduced number of functional glutamatergic synapses in hippocampal neurons overexpressing full-length TrkB receptors.
Klau, M; Hartmann, M; Erdmann, K S; Heumann, R; Lessmann, V
In: Journal of neuroscience research, Vol. 66, 2002, S. 327-36, ISSN Print0360-4012
2001
Synaptic secretion of BDNF after high-frequency stimulation of glutamatergic synapses.
Hartmann, M; Heumann, R; Lessmann, V
In: The EMBO journal, Vol. 20, 2001, S. 5887-97, ISSN Print0261-4189, 10.1093/emboj/20.21.5887
NT-3 regulates BDNF-induced modulation of synaptic transmission in cultured hippocampal neurons.
Paul, J; Gottmann, K; Lessmann, V
In: Neuroreport, Vol. 12, 2001, S. 2635-9, ISSN Print0959-4965
Semaphorin4F interacts with the synapse-associated protein SAP90/PSD-95.
Schultze, W; Eulenburg, V; Lessmann, V; Herrmann, L; Dittmar, T; Gundelfinger, E D; Heumann, R; Erdmann, K S
In: Journal of neurochemistry, Vol. 78, 2001, S. 482-9, ISSN Print0022-3042
2000
Fast, convenient, and effective method to transiently transfect primary hippocampal neurons.
Köhrmann, M; Haubensak, W; Hemraj, I; Kaether, C; Lessmann, V J; Kiebler, M A
In: Journal of neuroscience research, Vol. 58, 2000, S. 831-5, ISSN Print0360-4012
Protein expression patterns of identified neurons and of sprouting cells from the leech central nervous system.
Wu, X; Ritter, B; Schlattjan, J H; Lessmann, V; Heumann, R; Dietzel, I D
In: Journal of neurobiology, Vol. 44, 2000, S. 320-32, ISSN Print0022-3034
The Adenomatous Polyposis Coli-protein (APC) interacts with the protein tyrosine phosphatase PTP-BL via an alternatively spliced PDZ domain.
Erdmann, K S; Kuhlmann, J; Lessmann, V; Herrmann, L; Eulenburg, V; Müller, O; Heumann, R
In: Oncogene, Vol. 19, 2000, S. 3894-901, ISSN Print0950-9232, 10.1038/sj.onc.1203725
1999
Modulation of unitary glutamatergic synapses by neurotrophin-4/5 or brain-derived neurotrophic factor in hippocampal microcultures: presynaptic enhancement depends on pre-established paired-pulse facilitation.
Lessmann, V; Heumann, R
In: Neuroscience, Vol. 86, 1999, S. 399-413, ISSN Print0306-4522
1998
BDNF-GFP containing secretory granules are localized in the vicinity of synaptic junctions of cultured cortical neurons.
Haubensak, W; Narz, F; Heumann, R; Lessmann, V
In: Journal of cell science, Vol. 111 ( Pt 11), 1998, S. 1483-93, ISSN Print0021-9533
Neurotrophin-dependent modulation of glutamatergic synaptic transmission in the mammalian CNS.
Lessmann, V
In: General pharmacology, Vol. 31, 1998, S. 667-74, ISSN Print0306-3623
1997
Cyclic AMP endogenously enhances synaptic strength of developing glutamatergic synapses in serum-free microcultures of rat hippocampal neurons.
Lessmann, V; Heumann, R
In: Brain research, Vol. 763, 1997, S. 111-22, ISSN Print0006-8993
Differential modulation of AMPA receptor mediated currents by evans blue in postnatal rat hippocampal neurones.
Schürmann, B; Wu, X; Dietzel, I D; Lessmann, V
In: British journal of pharmacology, Vol. 121, 1997, S. 237-47, ISSN Print0007-1188, 10.1038/sj.bjp.0701125
1995
Two kinetically distinct 5-hydroxytryptamine-activated Cl- conductances at Retzius P-cell synapses of the medicinal leech.
Lessmann, V; Dietzel, I D
In: The Journal of neuroscience : the official journal of the Society for Neuroscience, Vol. 15, 1995, S. 1496-505, ISSN Print0270-6474
Fast desensitization of glutamate activated AMPA/kainate receptors in rat thalamic neurones.
Lessmann, V; Gottmann, K
In: Neuroreport, Vol. 5, 1995, S. 2253-6, ISSN Print0959-4965
BDNF and NT-4/5 enhance glutamatergic synaptic transmission in cultured hippocampal neurones.
Lessmann, V; Gottmann, K; Heumann, R
In: Neuroreport, Vol. 6, 1995, S. 21-5, ISSN Print0959-4965
Enhancement of postsynaptic serotonin-activated Cl- currents by depolarization-induced Ca2+ entry into leech neurons.
Lessmann, V; Dietzel, I D
In: Neuroscience, Vol. 67, 1995, S. 525-9, ISSN Print0306-4522
1993
Evans blue reduces macroscopic desensitization of non-NMDA receptor mediated currents and prolongs excitatory postsynaptic currents in cultured rat thalamic neurons.
Lessmann, V; Gottmann, K; Lux, H D
In: Neuroscience letters, Vol. 146, 1993, S. 13-6, ISSN Print0304-3940
1991
Development of serotonin-induced ion currents in identified embryonic Retzius cells from the medicinal leech (Hirudo medicinalis).
Lessmann, V; Dietzel, I D
In: The Journal of neuroscience : the official journal of the Society for Neuroscience, Vol. 11, 1991, S. 800-9, ISSN Print0270-6474
1990
Alterations in glycosylation and lectin pattern during phorbol ester-induced differentiation of U937 cells.
Hass, R; Köhler, L; Rehfeldt, W; Lessmann, V; Müller, W; Resch, K; Goppelt-Struebe, M
In: Cancer research, Vol. 50, 1990, S. 323-7, ISSN Print0008-5472