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Ionic cobalt but not metal particles induces ROS generation in immune cells in vitro
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Notch-signaling activity determines uptake and biological effect of imatinib in systemic sclerosis dermal fibroblasts
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Periprosthetic hypoxia as consequence of TRPM7 mediated cobalt influx in osteoblasts
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Soluble syndecans - biomarkers for diseases and therapeutic options
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Syndecan-4 is increased in osteoarthritic knee, but not hip or shoulder, articular hypertrophic chondrocytes
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BCP crystals drive chondrocyte hypertrophic differentiation via binding WNT ligands and activation of canonical WNT signaling
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Influence of cobalt (II) + and chromium (III)-ions on bone formation in human osteoblast-like cells in-vitro
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Inhibition of the complement system component C5 as possible treatment in OA
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Initial results on energy harvesting by exploiting the temperature gradient in hip implants
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Programmed cell death and toll-like receptor activation in articular cartilage
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Transient receptor potential cation channel (TRPC6) as a regulator of CXCR2-mediated articular cartilage homeostasis
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Calcification of the acetabular labrum of the hip - prevalence in the general population and relation to hip articular cartilage and fibrocartilage degeneration
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Ceramic prosthesis surfaces induce an inflammatory cell response and fibrotic tissue changes
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Differential effect of cobalt and chromium ions as well as CoCr particles on the expression of osteogenic markers and osteoblast function
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Targeting β-catenin dependent Wnt signaling via peptidomimetic inhibitors in murine chondrocytes and OA cartilage
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The effects of cobalt and chromium ions on transforming growth factor-beta patterns and mineralization in human osteoblast-like MG63 and SaOs-2 cells
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The terminal complement pathway is activated in septic but not in aseptic shoulder revision arthroplasties
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Calcium crystals and their link to osteoarthritis
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Nucleotide binding TLR dependent signalling cascades are activated upon cartilage trauma
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Shed syndecan 4 in synovial fluid as a biomarker for OA severity
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Syndecan-4 deficiency affects extracellular matrix architecture of articular cartilage
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The role of transient receptor potential cation channel trpc6 activity in cxcr2-mediated chondrocyte phenotypic stability
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Importance of the novel organic cation transporter 1 for tyrosine kinase inhibition by saracatinib in rheumatoid arthritis synovial fibroblasts
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Forced exercise-induced osteoarthritis is attenuated in mice lacking the small leucine-rich proteoglycan decorin
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Role of proteoglycans in osteoarthritis
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Activation of the transient receptor potential cation channel TRPC6 is required for chondrocyte phenotypic stability
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Altered matrix stiffness in decorin-null articular cartilage results in improved resistance to osteoarthritis induced by forced exercise
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Pharmacological blockade of CAMKII is detrimental for osteoarthritis progression
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Role of toll like receptor 3 in cartilage homoeostasis during posttraumatic and degenerative osteoarthritis
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Shed syndecan-4 in synovial fluid is a marker of osteoarthritis severity
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MATE1 regulates cellular uptake and sensitivity to imatinib in CML patients
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Articular cartilage calcification of the hip and knee is highly prevalent, independent of age but associated with histological osteoarthritis: evidence for a systemic disorder
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Articular cartilage calcification of the humeral head is highly prevalent and associated with osteoarthritis in the general population
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Hyaline cartilage calcification of the first metatarsophalangeal joint is associated with osteoarthritis but independent of age and BMI
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Arthrose
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Critical role for syndecan-4 in dendritic cell migration during development of allergic airway inflammation.
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Cellular and molecular mechanisms of cartilage damage and repair
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Manipulation of pro-inflammatory cytokine production by the bacterial cell-penetrating effector protein YopM is independent of its interaction with host cell kinases RSK1 and PRK2
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Regulation of matrixmetalloproteinase-3 and matrixmetalloproteinase-13 by SUMO-2/3 through the transcription factor NF-κB
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Syndecan 4 supports bone fracture repair, but not fetal skeletal development, in mice
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Syndecans in cartilage breakdown and synovial inflammation
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TRPC6 regulates CXCR2-mediated chemotaxis of murine neutrophils
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Decreased levels of nucleotide pyrophosphatase phosphodiesterase 1 are associated with cartilage calcification in osteoarthritis and trigger osteoarthritic changes in mice
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News from the osteoarthritis research [Neues aus der Arthroseforschung]
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Pathogenetic-oriented therapies for osteoarthritis - Are new DMOADS on the way? [Pathogenetisch orientierte therapieansätze bei der osteoarthrose - Sind DMOADs in der pipeline?]
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Transient receptor potential canonical channel 1 impacts on mechanosignaling during cell migration.
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Transport Mechanisms and Their Pathology-Induced Regulation Govern Tyrosine Kinase Inhibitor Delivery in Rheumatoid Arthritis
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WNT-3A modulates articular chondrocyte phenotype by activating both canonical and noncanonical pathways
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Cartilage biology, pathology, and repair
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Molecular mechanisms of cartilage remodelling in osteoarthritis
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Calcification of articular cartilage in human osteoarthritis
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Syndecan-4 regulates ADAMTS-5 activation and cartilage breakdown in osteoarthritis
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Gender differences in cardiac arrhythmias
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Role of sequence variations in the human ether-a-go-go-related gene (HERG, KCNH2) in the Brugada syndrome
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Amino acid substitutions in putative selectivity filter regions III and IV in KdpA alter ion selectivity of the KdpFABC complex from Escherichia coli
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The Methanocaldococcus jannaschii protein Mj0968 is not a P-type ATPase
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