Publikationen
2025
Begutachteter Zeitschriftenartikel
CSN-CRL complexes - new regulators of adipogenesis
Dubiel, Dawadschargal; Naumann, Michael; Dubiel, Wolfgang
In: Biomolecules - Basel : MDPI, Bd. 15 (2025), Heft 3, Artikel 372, insges. 14 S.
The enigma of maladaptation in gastric pathophysiology
Maubach, Gunter; Kanthasamy, Arun K.; Gogia, Sandro; Naumann, Michael
In: Trends in cancer - Amsterdam : Elsevier, Bd. 11 (2025), Heft 5, S. 448-461
Ablation of the deubiquitinating enzyme cylindromatosis (CYLD) augments STAT1-mediated M1 macrophage polarization and fosters Staphylococcus aureus control
Schmidt, Christina; Harit, Kunjan; Traidl, Stephan; Naumann, Michael; Werfel, Thomas; Rösner, Lennart Matthias; Nishanth, Gopala; Schlüter, Dirk
In: Frontiers in immunology - Lausanne : Frontiers Media, Bd. 16 (2025), Artikel 1507989, insges. 15 S.
Activation and reactivity of the deubiquitinylase OTU Cezanne-2 from MD simulations and QM/MM calculations
Ilter, Metehan; Escorcia, Andrés M.; Schulze-Niemand, Eric; Naumann, Michael; Stein, Matthias
In: Journal of chemical information and modeling - Washington, DC : American Chemical Society, Bd. 65 (2025), Heft 2, S. 921-936
Staphylococcal SplA and SplB serine proteases target ubiquitin(-like) specific proteases
Glinka, Felix L.; Schmöker, Ole; Singh, Abhishek K.; Steil, Leif; Hentschker, Christian; Völker, Uwe; Böttcher, Dominique; Lammers, Michael; Cammann, Clemens; Seifert, Ulrike; Krüger, Elke Helene; Naumann, Michael; Bröker, Barbara; Bornscheuer, Uwe Theo
In: AMB express - Heidelberg : Springer, Bd. 15 (2025), Artikel 32, insges. 9 S.
ALPK1-dependent cIAP1 degradation regulates Helicobacter pylori-induced apoptosis
Maubach, Gunter; Lim, Michelle Chin Chia; Naumann, Michael
In: The FASEB journal / Federation of American Societies for Experimental Biology - Hoboken, NJ : Wiley, Bd. 39 (2025), Heft 10, Artikel e70593, insges. 5 S.
Differential expression of the ubiquitin-editing enzyme A20 in gastric biopsies indicates the severity of disease
Schnizler, Stephan; Naumann, Michael; Vieth, Michael
In: Histochemistry and cell biology - Berlin : Springer, Bd. 163 (2025), Artikel 22, insges. 9 S.
2024
Abstract
Microenvironment-dependent stress response signaling in H. pylori-infected cells
Amirkhizi, Behzad; Jantaree, Phatcharida; Täger, Christian; Naumann, Michael
In: Die Innere Medizin - Berlin : Springer Medizin, Bd. 65 (2024), Heft Supplement 1, S. S6, Artikel YIA03
Begutachteter Zeitschriftenartikel
Gene content, phage cycle regulation model and prophage inactivation disclosed by prophage genomics in the Helicobacter pylori Genome Project
Vale, Filipa F.; Roberts, Richard J.; Kobayashi, Ichizo; Camargo, M. Constanza; Rabkin, Charles S.; Link, Alexander; Malfertheiner, Peter; Naumann, Michael
In: Gut microbes - Austin, Tex. : Landes Bioscience, Bd. 16 (2024), Heft 1, Artikel 2379440, insges. 29 S.
Ascorbate - a forgotten component in the cytotoxicity of Cu(II) ATCUN peptide complexes
Heinrich, Julian; Siddiqui, Elisa; Eckstein, Henrike; Naumann, Michael; Kulak, Nora
In: Journal of biological inorganic chemistry - Berlin : Springer, Bd. 29 (2024), Heft 7-8, S. 801-809
Cortactin-dependent control of Par1b-regulated epithelial cell polarity in Helicobacter infection
Sharafutdinov, Irshad; Harrer, Aileen; Müsken, Mathias; Rottner, Klemens; Sticht, Heinrich; Täger, Christian; Naumann, Michael; Tegtmeyer, Nicole; Backert, Steffen
In: Cell insight - [Amsterdam] : Elsevier B.V., Bd. 3 (2024), Heft 3, Artikel 100161, insges. 16 S.
Harnessing gastrointestinal organoids for cancer therapy
Maubach, Gunter; Naumann, Michael
In: Trends in molecular medicine - Amsterdam [u.a.] : Elsevier Science, Bd. 30 (2024), Heft 7, S. 617-619
Discovery of biosynthetic enzymes for β-D-manno-heptoses across kingdoms - novel agonists for ALPK1/NF-κB-dependent immune response
Maubach, Gunter; Lim, Michelle Chin Chia; Naumann, Michael
In: Signal transduction and targeted therapy - London : Macmillan Publishers, part of Springer Nature, Bd. 9 (2024), Artikel 277, insges. 3 S.
2023
Buchbeitrag
Gastric epithelial barrier disruption, inflammation and oncogenic signal transduction by Helicobacter pylori
Naumann, Michael; Ferino, Lorena; Sharafutdinov, Irshad; Backert, Steffen
In: Helicobacter pylori and gastric cancer - Cham : Springer . - 2023, S. 207-238
Begutachteter Zeitschriftenartikel
CD248 induces a maladaptive unfolded protein response in diabetic kidney disease
Krishnan, Shruthi; Manoharan, Jayakumar; Wang, Hongjie; Gupta, Dheerendra; Fatima, Sameen; Yu, Yanfei; Mathew, Akash; Li, Zhen; Kohli, Shrey; Schwab, Constantin; Körner, Antje; Mertens, Peter R.; Nawroth, Peter Paul; Shahzad Hussain, Khurrum; Naumann, Michael; Isermann, Berend; Biemann, Ronald
In: Kidney international - New York, NY : Elsevier, Bd. 103 (2023), Heft 2, S. 304-319, insges. 16 S.
ZOMES - cell physiology determined by PCI complexes and protein turnover
Dubiel, Dawadschargal; Fonseca, Paula C.; Valás̆ek, Leos̆ Shivaya; Schulze-Niemand, Eric; Naumann, Michael
In: Biochimica et biophysica acta / Molecular cell research - Amsterdam [u.a.] : Elsevier, Bd. 1870 (2023), Heft 2, Artikel 119402
Structural dynamics of Lys11-selective deubiquitinylase Cezanne-1 during the catalytic cycle
Ilter, Metehan; Schulze-Niemand, Eric; Naumann, Michael; Stein, Matthias
In: Journal of chemical information and modeling - Washington, DC : American Chemical Society, Bd. 63 (2023), Heft 7, S. 2084-2094
Synthesis and structure–activity relationships of USP48 deubiquitinylase inhibitors
Böhm, Kevin; Schulze-Niemand, Eric; Kähne, Thilo; Siddiqui, Elisa; Täger, Christian; Ramsbeck, Daniel Lars; Buchholz, Mirko; Naumann, Michael
In: Archiv der Pharmazie - Weinheim : Wiley-VCH, Bd. 356 (2023), Artikel e2200661, insges. 17 S.
The conundrum of Helicobacter pylori-associated apoptosis in gastric cancer
Lim, Michelle Chin Chia; Jantaree, Phatcharida; Naumann, Michael
In: Trends in cancer - Amsterdam : Elsevier, Bd. 9 (2023), Heft 8, S. 679-690
Inhibition of EIF2α dephosphorylation decreases cell viability and synergizes with standard-of-care chemotherapeutics in head and neck squamous cell carcinoma
Cyran, Anna M.; Kleinegger, Florian; Naß, Norbert; Naumann, Michael; Haybäck, Johannes; Arens, Christoph
In: Cancers - Basel : MDPI, Bd. 15 (2023), Heft 22, Artikel 5350, insges. 22 S.
Decreased eukaryotic initiation factors expression upon temozolomide treatment - potential novel implications for eIFs in glioma therapy
Krassnig, Stefanie; Leber, Stefan L.; Orthmann, Andrea; Golob-Schwarzl, Nicole; Huber, Heinrich Johann; Wohlrab, Christina; Skofler, Christina; Pennauer, Mirjam Vera; Raicht, Andrea; Birkl-Toeglhofer, Anna Maria; Naumann, Michael; Mahdy-Ali, Kariem; Campe, Gord; Leoni, Marlene; Alcaniz, Joshua; Hoffmann, Jens; Wälchli, Thomas; Weis, Serge; Benesch, Martin; Haybäck, Johannes
In: Journal of neuro-oncology - Dordrecht [u.a.] : Springer Science + Business Media B.V, Bd. 165 (2023), Heft 1, S. 91-100
The Helicobacter pylori Genome Project - insights into H. pylori population structure from analysis of a worldwide collection of complete genomes
Thorell, Kaisa; Muñoz-Ramírez, Zilia Y.; Wang, Difei; Sandoval-Motta, Santiago; Agostini, Rajiv Boscolo; Ghirotto, Silvia; Torres, Roberto C.; Falush, Daniel; Camargo, M. Constanza; Rabkin, Charles S.; Malfertheiner, Peter; Naumann, Michael
In: Nature Communications - [London] : Nature Publishing Group UK, Bd. 14 (2023), Artikel 8184, insges. 16 S.
Helicobacter pylori regulates TIFA turnover in gastric epithelial cells
Sokolova, Olga; Maubach, Gunter; Naumann, Michael
In: European journal of cell biology - München : Elsevier, Bd. 102 (2023), Heft 2, Artikel 151307, insges. 14 S.
Latent CSN-CRL complexes are crucial for curcumin-induced apoptosis and recruited during adipogenesis to lipid droplets via small GTPase RAB18
Dubiel, Dawadschargal; Wang, Jing; Hartig, Roland; Chaithongyot, Supattra; Dubiel, Wolfgang; Naumann, Michael
In: iScience - Amsterdam : Elsevier, Bd. 26 (2023), Heft 4, Artikel 106468, insges. 22 S.
The COP9 signalosome - a versatile regulatory hub of Cullin-RING ligases
Schulze-Niemand, Eric; Naumann, Michael
In: Trends in biochemical sciences - Amsterdam [u.a.] : Elsevier Science, Bd. 48 (2023), Heft 1, S. 82-95
MAPT genotype-dependent mitochondrial aberration and ROS production trigger dysfunction and death in cortical neurons of patients with hereditary FTLD
Korn, Lisanne; Speicher, Anna Martina; Menskes, Christina Barbara; Gola, Lukas; Kaehne, Thilo; Engler, Alexander; Disse, Paul; Fernandez-Orth, Juncal; Csatári, Júlia; Naumann, Michael; Seebohm, Guiscard Friedrich Aldous; Meuth, Sven; Schöler, Hans Robert; Wiendl, Heinz; Kovać, Stjepana; Pawlowski, Matthias
In: Redox Biology - Amsterdam [u.a.] : Elsevier, Bd. 59 (2023), Artikel 102597, insges. 13 S.
Dissertation
Role of USP48 and A20 on cell survival of gastric epithelium during Helicobacter pylori infection
Jantaree, Phatcharida; Naumann, Michael
In: Magdeburg: Universitätsbibliothek, Dissertation Otto-von-Guericke-Universität Magdeburg, Fakultät für Naturwissenschaften 2023, 1 Online-Ressource (80 Blätter, 11,23 MB) [Literaturverzeichnis: Blatt 68-79]
2022
Begutachteter Zeitschriftenartikel
Ubiquitin-modifying enzymes as regulators of colitis
Ruan, Jing; Schlüter, Dirk; Naumann, Michael; Waisman, Ari; Wang, Xu
In: Trends in molecular medicine - Amsterdam [u.a.] : Elsevier Science, Bd. 28 (2022), Heft 4, S. 304-318
A20 undermines alternative NF-[kappa]B activity and expression of anti-apoptotic genes in Helicobacter pylori infection
Lim, Michelle Chin Chia; Maubach, Gunter; Birkl-Toeglhofer, Anna M.; Haybäck, Johannes; Vieth, Michael; Naumann, Michael
In: Cellular and molecular life sciences - Cham (ZG) : Springer International Publishing AG, Bd. 79 (2022), Heft 2, Artikel 102, insges. 12 S.
Ca2+ signaling in postsynaptic neurons - neuroplastin-65 regulates the interplay between plasma membrane Ca2+ ATPases and ionotropic glutamate receptors
Malci, Ayse; Lin, Xiao; Sandoval, Rodrigo; Gundelfinger, Eckart D.; Naumann, Michael; Seidenbecher, Constanze; Herrera-Molina, Rodrigo
In: Cell calcium - Edinburgh [u.a.]: Churchill Livingstone, 1980, Bd. 106 (2022), insges. 14 S.
USP48 and A20 synergistically promote cell survival in Helicobacter pylori infection
Jantaree, Phatcharida; Chaithongyot, Supattra; Sokolova, Olga; Naumann, Michael
In: Cellular and molecular life sciences - Cham (ZG) : Springer International Publishing AG, Bd. 79 (2022), Artikel 461, insges. 13 S.
Helicobacter pylori-induced NF-[kappa]B - trailblazer for gastric pathophysiology
Maubach, Gunter; Vieth, Michael; Boccellato, Francesco; Naumann, Michael
In: Trends in molecular medicine - Amsterdam [u.a.] : Elsevier Science, Bd. 28 (2022), Heft 3, S. 210-222
Ovarian tumor domain proteases in pathogen infection
Schlüter, Dirk; Schulze-Niemand, Eric; Stein, Matthias; Naumann, Michael
In: Trends in microbiology - Amsterdam [u.a.]: Elsevier Science, Bd. 30 (2022), 1, S. 22-33
Matrix metalloproteinases in Helicobacter pylori-associated gastritis and gastric cancer
Sokolova, Olga; Naumann, Michael
In: International journal of molecular sciences - Basel : Molecular Diversity Preservation International, Bd. 23 (2022), Heft 3, Artikel 1883, insges. 17 S.
Human gastric fibroblasts ameliorate A20-dependent cell survival in co-cultured gastric epithelial cells infected by Helicobacter pylori
Jantaree, Phatcharida; Yu, Yanfei; Chaithongyot, Supattra; Täger, Christian; Abdi Sarabi, Mohsen; Meyer, Thomas F.; Boccellato, Francesco; Maubach, Gunter; Naumann, Michael
In: Biochimica et biophysica acta / Molecular cell research - Amsterdam [u.a.] : Elsevier, Bd. 1869 (2022), Heft 12, Artikel 119364
Substrate-assisted activation and selectivity of the bacterial RavD effector deubiquitinylase
Schulze-Niemand, Eric; Naumann, Michael; Stein, Matthias
In: Proteins - New York, NY: Wiley-Liss, 1986, Bd. 90 (2022), 4, S. 947-958
Helicobacter pylori-induced reactive oxygen species direct turnover of CSN-associated STAMBPL1 and augment apoptotic cell death
Chaithongyot, Supattra; Naumann, Michael
In: Cellular and molecular life sciences - Cham (ZG) : Springer International Publishing AG, Bd. 79 (2022), Heft 2, Artikel 86, insges. 16 S.
Dissertation
Function of STAMBPL1 in Helicobacter pylori-associated cell death
Chaithongyot, Supattra; Naumann, Michael
In: Magdeburg: Universitätsbibliothek, Dissertation Otto-von-Guericke-Universität Magdeburg, Fakultät für Naturwissenschaften 2022, 1 Online-Ressource (ii, 82 Blätter, 3,89 MB) [Literaturverzeichnis: Blatt 64-81]
Molecular recognition and selectivity - computational investigations on the dynamics of non-bonded interactions
Schulze-Niemand, Eric; Naumann, Michael
In: Magdeburg: Universitätsbibliothek, Dissertation Otto-von-Guericke-Universität Magdeburg, Fakultät für Verfahrens- und Systemtechnik 2022, 1 Online-Ressource (192, XV, 13,18 MB) [Literaturverzeichnis: Seite 173-192][Literaturverzeichnis: Seite 173-192]
Function of A20 in the regulation of Helicobacter pylori-induced alternative NK-B and caspase-8-dependent apoptotic cell death
Lim, Michelle Chin Chia; Naumann, Michael
In: Magdeburg: Universitätsbibliothek, Dissertation Otto-von-Guericke-Universität Magdeburg, Fakultät für Naturwissenschaften 2022, 1 Online-Ressource (XI, 90 Seiten, 3,51 MB) [Literaturverzeichnis: Seite 69-89]
2021
Begutachteter Zeitschriftenartikel
NF-[kappa]B in gastric cancer development and therapy
Chaithongyot, Supattra; Jantaree, Phatcharida; Sokolova, Olga; Naumann, Michael
In: Biomedicines - Basel : MDPI, Bd. 9 (2021), Heft 8, Artikel 870, insges. 21 S.
Manifold role of ubiquitin in Helicobacter pylori infection and gastric cancer
Sokolova, Olga; Naumann, Michael
In: Cellular and molecular life sciences - Cham (ZG): Springer International Publishing AG, Bd. 78 (2021), Heft 10, S. 4765-4783
Discovery of Zika virus host dependency factors in trophoblasts using CRISPR/Cas9 screening
Rother, Marion; Dimmler, Christiane; Weege, Friderike; Mollenkopf, Hans-Joachim; Meyer, Thomas F.; Naumann, Michael
In: Journal of virological methods - Amsterdam [u.a.]: Elsevier Science, Bd. 290 (2021)
Importance of cortactin for efficient epithelial NF-[kappa]B activation by Helicobacter pylori, Salmonella enterica and Pseudomonas aeruginosa, but not Campylobacter spp.
Tegtmeyer, Nicole; Esmaeili, Delara Soltan; Sharafutdinov, Irshad; Knorr, Jakob; Naumann, Michael; Alter, Thomas; Backert, Steffen
In: European journal of microbiology and immunology - Budapest : Akad. Kiadó, Bd. 11 (2021), Heft 4, S. 95-103
Interactome mapping of eIF3A in a colon cancer and an immortalized embryonic cell line using proximity-dependent biotin identification
Vo, Diep-Khanh Ho; Engler, Alexander; Stoimenovski, Darko; Hartig, Roland; Kaehne, Thilo; Kalinski, Thomas; Naumann, Michael; Haybäck, Johannes; Naß, Norbert
In: Cancers - Basel: MDPI, 2009, Bd. 13 (2021), 6, insges. 21 S.
OTUB1 prevents lethal hepatocyte necroptosis through stabilization of c-IAP1 during murine liver inflammation
Koschel, Josephin; Nishanth, Gopala; Just, Sissy; Harit, Kunjan; Kröger, Andrea; Deckert, Martina; Naumann, Michael; Schlüter, Dirk
In: Cell death and differentiation - Houndmills, Basingstoke: Nature Publishing Group, 1997, Bd. 28 (2021), 7, S. 2257-2275
Peptide microarray-based analysis of antibody responses to SARS-CoV-2 identifies unique epitopes with potential for diagnostic test development
Holenya, Pavlo; Lange, Paul Joris; Reimer, Ulf; Woltersdorf, Wolfram; Panterodt, Thomas; Glas, Michael; Wasner, Mark; Eckey, Maren; Drosch, Michael; Hollidt, Jörg-Michael; Naumann, Michael; Kern, Florian; Wenschuh, Holger; Lange, Robert; Schnatbaum, Karsten; Bier, Frank Fabian
In: European journal of immunology - Weinheim: Wiley-VCH, 1971, Bd. 51 (2021), 7, S. 1839-1849
The deubiquitinase OTUB1 augments NF-[kappa]B-dependent immune responses in dendritic cells in infection and inflammation by stabilizing UBC13
Mulas, Floriana; Wang, Xu; Song, Shanshan; Nishanth, Gopala; Yi, Wenjing; Brunn, Anna Gertrud; Larsen, Pia-Katharina; Isermann, Berend; Kalinke, Ulrich; Barragan, Antonio; Naumann, Michael; Deckert, Martina; Schlüter, Dirk
In: Cellular & molecular immunology - London [u.a.]: Nature Publ. Group, 2004, Bd. 18 (2021), 6, S. 1512-1527
From 3D back to 2D monolayer stomach organoids-on-a-chip
Jantaree, Phatcharida; Bakhchova, Liubov; Steinmann, Ulrike; Naumann, Michael
In: Trends in biotechnology - Amsterdam [u.a.] : Elsevier Science, Bd. 39 (2021), Heft 8, S. 745-748
The activation and selectivity of the Legionella RavD deubiquitinase
Schulze-Niemand, Eric; Naumann, Michael; Stein, Matthias
In: Frontiers in molecular biosciences - Lausanne: Frontiers, 2014, Bd. 8 (2021), insges. 4 S.
On-a-chip-based sensitive detection of drug-induced apoptosis in polarized gastric epithelial cells
Bakhchova, Liubov; Jantaree, Phatcharida; Gupta, Anubhuti; Isermann, Berend; Steinmann, Ulrike; Naumann, Michael
In: ACS biomaterials science & engineering / American Chemical Society - Washington, DC : ACS Publ., Bd. 7 (2021), Heft 12, S. 5474-5483
TIFA has dual functions in Helicobacter pylori-induced classical and alternative NF-[kappa]B pathways
Maubach, Gunter; Lim, Michelle Chin Chia; Sokolova, Olga; Backert, Steffen; Meyer, Thomas F.; Naumann, Michael
In: EMBO reports / European Molecular Biology Organization - Heidelberg : EMBO Press, Bd. 22 (2021), Heft 9, Artikel e52878, insges. 12 S.
Signal peptidase complex subunit 1 is an essential Zika virus host factor in placental trophoblasts
Rother, Marion; Naumann, Michael
In: Virus research - Amsterdam [u.a.] : Elsevier Science - Vol. 296.2021, 198338
2020
Abstract
Expression der eukaryotischen Initiationsfaktoren (eIFs) in plattenepithelialen Kopf- und Halskarzinomen (HNSCC) - potenzielle therapeutische Implikationen
Cyran, Anna-Maria; Naß, Norbert; Swierczynski, Piotr; Sprung, Susanne; Naumann, Michael; Haybäck, Johannes; Arens, Christoph
In: Laryngo-Rhino-Otologie - Stuttgart [u.a.]: Thieme, 1980, Bd. 99.2020, S 02, S. S90-S91
Begutachteter Zeitschriftenartikel
Activation and selectivity of OTUB-1 and OTUB-2 deubiquitinylases
Sivakumar, Dakshinamurthy; Kumar, Vikash; Naumann, Michael; Stein, Matthias
In: The journal of biological chemistry - Bethesda, Md.: Soc., 1905, Bd. 295.2020, 20, S. 6972-6982
The interaction of TRAF6 with neuroplastin promotes spinogenesis during early neuronal development
Vemula, Sampath Kumar; Malci, Ayse; Junge, Lennart; Lehmann, Anne-Christin; Rama, Ramya; Hradsky, Johannes; Matute, Ricardo A.; Weber, André; Prigge, Matthias; Naumann, Michael; Kreutz, Michael R.; Seidenbecher, Constanze; Gundelfinger, Eckart D.; Herrera-Molina, Rodrigo
In: Frontiers in cell and developmental biology - Lausanne: Frontiers Media, 2013, Vol. 8.2020, 579513, insgesamt 18 Seiten
The COP9 signalosome - a multi-DUB complex
Dubiel, Wolfgang; Chaithongyot, Supattra; Dubiel, Dawadschargal; Naumann, Michael
In: Biomolecules: open access journal - Basel: MDPI, 2011, Bd. 10.2020, 7, Art.-Nr. 1082, insgesamt 11 Seiten
CEACAMs interaction with Helicobacter pylori HopQ supports the type 4 secretion system-dependent activation of non-canonical NF-[kappa]B
Maubach, Gunter; Sokolova, Olga; Täger, Christian; Naumann, Michael
In: International journal of medical microbiology: IJMM - München: Elsevier, 2000, Bd. 310.2020, 6, Art.-Nr. 151444, insges. 6 Seiten
2019
Abstract
Expression levels of eukaryotic initiation factors (eIFs) are significantly altered in head and neck squamous cell carcinomas (HNSCC)
Cyran, Anna-Maria; Sprung, Susanne; Naß, Norbert; Naumann, Michael; Arens, Christoph; Haybäck, Johannes
In: Der Pathologe - Berlin: Springer, 1994, Bd. 40.2019, Suppl. 2, AG11.05, Seite S139
Neuroplastin-plasma membrane Ca2+ ATPases complexes - a new team regulating Ca2+ clearance, signaling, and synaptic plasticity
Malci, Ayse; Naumann, Michael; Gundelfinger, Eckart D.; Seidenbecher, Constanze; Herrera-Molina, Rodrigo
In: Journal of neurochemistry - Oxford: Wiley-Blackwell, 1956, Vol. 150.2019, Suppl. 1, MTU02-05, S. 77
Role of Otubain-1 (OTUB1) during inflammatory liver diseases
Koschel, Josephin; Nishanth, Gopala; Just, Sissy; Naumann, Michael; Schlüter, Dirk
In: European journal of immunology - Weinheim: Wiley-VCH, 1971, Bd. 49.2019, Suppl. 1, O1, Seite 13
Begutachteter Zeitschriftenartikel
Targeting RIPK1 in AML cells carrying FLT3-ITD
Hillert, Laura K.; Bettermann-Bethge, Kira; Nimmagadda, Subbaiah Chary; Fischer, Thomas; Naumann, Michael; Lavrik, Inna N.
In: International journal of cancer - Bognor Regis : Wiley-Liss, Bd. 145 (2019), Heft 6, S. 1558-1569
NF-kappaB-inducing kinase in cancer
Maubach, Gunter; Feige, Michael H.; Lim, Michelle Chin Chia; Naumann, Michael
In: Biochimica et biophysica acta / Reviews on cancer - Amsterdam : Elsevier, Bd. 1871 (2019), Heft 1, S. 40-49
Crosstalk between DNA damage and inflammation in the multiple steps of gastric carcinogenesis
Sokolova, Olga; Naumann, Michael
In: Current topics in microbiology and immunology - Berlin: Springer, Bd. 421.2019, S. 107-137
Catalytic domain of deubiquitinylase USP48 directs interaction with Rel homology domain of nuclear factor kappaB transcription factor RelA
Ghanem, Ahmed; Schweitzer, Katrin; Naumann, Michael
In: Molecular biology reports - Dordrecht [u.a.]: Springer Science + Business Media B.V, Bd. 46.2019, 1, S. 1369-1375
2018
Begutachteter Zeitschriftenartikel
Computational studies on the inhibitor selectivity of human JAMM deubiquitinylases Rpn11 and CSN5
Kumar, Vikash; Naumann, Michael; Stein, Matthias
In: Frontiers in Chemistry - Lausanne: Frontiers Media, Bd. 6.2018, Art.-Nr. 480, insges. 12 S.
Deubiquitinylase USP47 promotes RelA phosphorylation and survival in gastric cancer cells
Naghavi, Lara; Schwalbe, Martin; Ghanem, Ahmed; Naumann, Michael
In: Biomedicines: open access journal - Basel: MDPI, Bd. 6.2018, 2, Art.-Nr. 62, insges. 9 S.
Cullin 3-based ubiquitin ligases as master regulators of mammalian cell differentiation
Dubiel, Wolfgang; Dubiel, Dawadschargal; Wolf, Dieter A.; Naumann, Michael
In: Trends in biochemical sciences: TIBS - Amsterdam [u.a.]: Elsevier Science, Bd. 43 (2018), 2, S. 95-107
Constitutive activation of nuclear factor kappa B-inducing kinase counteracts apoptosis in cells with rearranged mixed lineage leukemia gene
Studencka-Turski, Maja; Maubach, Gunter; Feige, Michael Hartmut; Naumann, Michael
In: Leukemia: normal and malignant hemopoiesis ; a peer-reviewed journal - London: Springer Nature, Bd. 32 (2018), 11, S. 2498-2501
HopQ impacts the integrin [alpha]5[beta]1-independent NF-[kappa]B activation by Helicobacter pylori in CEACAM expressing cells
Feige, Michael Hartmut; Sokolova, Olga; Pickenhahn, Anna; Maubach, Gunter; Naumann, Michael
In: International journal of medical microbiology: IJMM - München: Elsevier, Bd. 308 (2018), 5, S. 527-533
Diverging impact of cell fate determinants Scrib and Llgl1 on adhesion and migration of hematopoietic stem cells
Dash, Banaja Priyadarshini; Schnöder, Tina; Kathner, Carolin; Mohr, Juliane; Weinert, Sönke; Herzog, Carolin; Godavarthy, Parimala Sonika; Zanetti, Costanza; Perner, Florian; Braun-Dullaeus, Rüdiger; Hartleben, Björn; Huber, Tobias B.; Walz, Gerd; Naumann, Michael; Ellis, Sarah; Vasioukhin, Valera; Kähne, Thilo; Krause, Daniela Sandra; Heidel, Florian
In: Journal of cancer research and clinical oncology: official organ of the Deutsche Krebsgesellschaft - Berlin: Springer, Bd. 144.2018, 10, S. 1933-1944
NF-[kappa]B-regulated ubiquitin-editing enzyme A20 paves the way for infection persistency
Lim, Michelle Chin Chia; Maubach, Gunter; Naumann, Michael
In: Cell cycle - Abingdon : Taylor & Francis Group, Bd. 17 (2018), Heft 1, S. 3-4
Influence of eukaryotic translation initiation factor 6 on nonsmall cell lung cancer development and progression
Gantenbein, Nadine; Bernhart, Eva; Anders, Ines; Golob-Schwarzl, Nicole; Krassnig, Stefanie; Wodlej, Christina; Brcic, Luka; Lindenmann, Joerg; Fink-Neuboeck, Nicole; Gollowitsch, Franz; Stacher-Priehse, Elvira; Asslaber, Martin; Gogg-Kamerer, Margit; Rolff, Jana; Hoffmann, Jens; Silvestri, Alessandra; Regenbrecht, Christian René Alexander; Reinhard, Christoph; Pehserl, Anna-Maria; Pichler, Martin; Sokolova, Olga; Naumann, Michael; Mitterer, Valentin; Pertschy, Brigitte; Bergler, Helmut; Popper, Helmut; Sattler, Wolfgang; Haybäck, Johannes
In: European journal of cancer - Amsterdam [u.a.]: Elsevier, 1965, Bd. 101.2018, S. 165-180
Interactome analysis of transforming growth factor-[beta]-activated kinase 1 in Helicobacter pylori-infected cells revealed novel regulators tripartite motif 28 and CDC37
Sokolova, Olga; Kähne, Thilo; Bryan, Kenneth; Naumann, Michael
In: OncoTarget - [S.l.] : Impact Journals LLC, Bd. 9 (2018), Heft 18, S. 14366-14381
Helicobacter pylori induces direct activation of the lymphotoxin beta receptor and non-canonical nuclear factor-kappa B signaling
Feige, Michael Hartmut; Vieth, Michael; Sokolova, Olga; Täger, Christian; Naumann, Michael
In: Biochimica et biophysica acta / Molecular cell research: BBA - Amsterdam [u.a.]: Elsevier, Bd. 1865 (2018), 4, S. 545-550
The cell fate determinant Scribble is required for maintenance of hematopoietic stem cell function
Mohr, Juliane; Dash, Banaja Priyadarshini; Schnöder, Tina; Wolleschak, Denise; Herzog, Carolin; Santamaria, Nuria Tubio; Weinert, Sönke; Godavarthy, Sonika; Zanetti, Costanza; Naumann, Michael; Hartleben, Björn; Huber, Tobias B.; Krause, Daniela Sandra; Kähne, Thilo; Bullinger, Lars; Heidel, Florian
In: Leukemia: normal and malignant hemopoiesis ; a peer-reviewed journal - London: Springer Nature, Bd. 32.2018, 5, S. 1211-1221
2017
Abstract
CYLD-deficiency protects from experimental cerebral malaria
Schmid, Ursula; Stenzel, Werner; Koschel, Josephin; Raptaki, Maria; Wang, Xu; Naumann, Michael; Matuschewski, Kai; Schlüter, Dirk; Nishanth, Gopala
In: European journal of immunology - Weinheim: Wiley, 1971, Bd. 47.2017, Suppl. 2, O74, S. 42
A new way to create synapses - neuroplastin-TRAF6-dependent signaling induces excitatory synapse formation
Herrera-Molina, Rodrigo; Vemula, Sampath Kumar; Naumann, Michael; Seidenbecher, Constanze; Gundelfinger, Eckart D.
In: Journal of neurochemistry - Oxford: Wiley-Blackwell, 1956, Bd. 142.2017, Suppl. 1, MTU08-08, S. 130
Begutachteter Zeitschriftenartikel
Cul3 neddylation is crucial for gradual lipid droplet formation during adipogenesis
Dubiel, Dawadschargal; Bintig, Willem; Kähne, Thilo; Dubiel, Wolfgang; Naumann, Michael
In: Biochimica et biophysica acta / Molecular cell research: BBA - Amsterdam [u.a.]: Elsevier, Bd. 1864 (2017), 8, S. 1405-1412
ALPK1- and TIFA-dependent innate immune response triggered by the helicobacter pylori type IV secretion system
Zimmermann, Stephanie; Pfannkuch, Lennart; Al-Zeer, Munir A.; Bartfeld, Sina; Koch, Manuel; Liu, Jianping; Rechner, Cindy; Soerensen, Meike; Sokolova, Olga; Zamyatina, Alla; Kosma, Paul; Mäurer, André Germar Paul; Glowinski, Frithjof; Pleissner, Klaus-Peter; Schmid, Monika; Brinkmann, Volker; Karlas, Alexander; Naumann, Michael; Rother, Marion; Machuy, Nikolaus; Meyer, Thomas F.
In: Cell reports - Maryland Heights, MO: Cell Press, 2012, Bd. 20 (2017), 10, S. 2384-2395
The deubiquitinating enzyme cylindromatosis dampens CD8+ T cell responses and is a critical factor for experimental cerebral malaria and bloodbrain barrier damage
Schmid, Ursula; Stenzel, Werner; Koschel, Josephin; Raptaki, Maria; Wang, Xu; Naumann, Michael; Matuschewski, Kai; Schlüter, Dirk; Nishanth, Gopala
In: Frontiers in immunology - Lausanne: Frontiers Media, 2010, Bd. 8.2017, Art.-Nr. 27, insges. 17 S.
Pathogen-induced ubiquitin-editing enzyme A20 bifunctionally shuts off NF-κB and caspase-8-dependent apoptotic cell death
Lim, Michelle Chin Chia; Maubach, Gunter; Sokolova, Olga; Feige, Michael H.; Diezko, Rolf Christian; Buchbinder, Jörn; Backert, Steffen; Schlüter, Dirk; Lavrik, Inna N.; Naumann, Michael
In: Cell death and differentiation - Houndmills, Basingstoke : Nature Publishing Group, Bd. 24 (2017), Heft 9, S. 1621-1631
Double phosphorylation-induced structural changes in the signal-receiving domain of IκBα in complex with NF-κB
Yazdi, Samira; Naumann, Michael; Stein, Matthias
In: Proteins: Structure, Function, and Bioinformatics, 2017, S. 17-29, ISSN 08873585, 10.1002/prot.25181
The Helicobacter pylori type IV secretion system encoded by the cag pathogenicity island - architecture, function, and signaling
Backert, Steffen; Haas, Rainer; Gerhard, Markus; Naumann, Michael
In: Current topics in microbiology and immunology - Berlin: Springer, Bd. 413.2017, S. 187-220
A dual role of caspase-8 in triggering and sensing proliferation-associated DNA damage, a key determinant of liver cancer development
Böge, Yannick Thimotheus; Malehmir, Mohsen; Healy, Marc E.; Bettermann, Kira; Lorentzen, Anna; Vucur, Mihael; Ahuja, Akshay Kumar; Böhm, Friederike; Mertens, Joachim C.; Shimizu, Yutaka; Frick, Lukas; Remouchamps, Caroline; Mutreja, Karun; Kähne, Thilo; Sundaravinayagam, Devakumar; Wolf, Monika J.; Rehrauer, Hubert; Koppe, Christiane; Speicher, Tobias; Padrissa-Altés, Susagna; Maire, Renaud; Schattenberg, Jörn Markus; Jeong, Ju-Seong; Liu, Lei; Zwirner, Stefan; Boger, Regina; Hüser, Norbert; Davis, Roger J.; Müllhaupt, Beat; Moch, Holger; Schulze-Bergkamen, Henning; Clavien, Pierre-Alain; Werner, Sabine; Borsig, Lubor; Luther, Sanjiv A.; Jost, Philipp J.; Weinlich, Ricardo; Unger, Kristian; Behrens, Axel; Hillert, Laura; Dillon, Christopher; Virgilio, Michela; Wallach, David; Dejardin, Emmanuel; Zender, Lars; Naumann, Michael; Walczak, Henning; Green, Douglas R.; Lopes, Massimo; Lavrik, Inna N.; Lüdde, Tom; Heikenwälder, Mathias; Weber, Achim
In: Cancer cell - Cambridge, Mass. : Cell Press, Bd. 32 (2017), Heft 3, S. 342-359
A complex of neuroplastin and plasma membrane Ca2+ ATPase controls T cell activation
Korthals, Mark; Langnaese, Kristina; Smalla, Karl-Heinz; Kähne, Thilo; Herrera-Molina, Rodrigo; Handschuh, Juliane; Lehmann, Anne-Christin; Mamula, Dejan; Naumann, Michael; Seidenbecher, Constanze; Zuschratter, Werner; Tedford, Kerry; Gundelfinger, Eckart D.; Montag, Dirk; Fischer, Klaus-Dieter; Thomas, Ulrich
In: Scientific reports - [London]: Macmillan Publishers Limited, part of Springer Nature, 2011, Bd. 7.2017, Art.-Nr. 8358, insges. 13 S.
Double phosphorylation-induced structural changes in the signal-receiving domain of I[kappa]B[alpha] in complex with NF-[kappa]B
Yazdi, Samira; Naumann, Michael; Stein, Matthias
In: Proteins - New York, NY : Wiley-Liss, Bd. 85 (2017), Heft 1, S. 17-29
Helicobacter pylori employs a unique basolateral type IV secretion mechanism for CagA delivery
Tegtmeyer, Nicole; Weßler, Silja; Necchi, Vittorio; Rohde, Manfred; Harrer, Aileen; Rau, Tilman Tassilo Rupert; Asche, Carmen Isabell; Boehm, Manja; Lößner, Holger; Figueiredo, Ceu; Naumann, Michael; Palmisano, Ralf; Solcia, Enrico; Ricci, Vittorio; Backert, Steffen
In: Cell host and microbe - Amsterdam [u.a.]: Elsevier, Bd. 22.2017, 4, S. 552-560
Activated protein C protects from GvHD via PAR2/PAR3 signalling in regulatory T-cells
Ranjan, Satish; Goihl, Alexander; Kohli, Shrey; Gadi, Ihsan; Pierau, Mandy; Shahzad Hussain, Khurrum; Gupta, Dheerendra; Bock, Fabian; Wang, Hongjie; Shaikh, Haroon; Kähne, Thilo; Reinhold, Dirk; Bank, Ute; Zenclussen, Ana Claudia; Niemz, Jana; Schnöder, Tina; Brunner-Weinzierl, Monika; Fischer, Thomas; Kalinski, Thomas; Schraven, Burkhart; Luft, Thomas; Hühn, Jochen; Naumann, Michael; Heidel, Florian; Isermann, Berend
In: Nature Communications - [London] : Nature Publishing Group UK - 8(2017) Artikel-Nummer 311, 16 Seiten
Helicobacter pylori - a paradigm pathogen for subverting host cell signal transmission
Naumann, Michael; Sokolova, Olga; Tegtmeyer, Nicole; Backert, Steffen
In: Trends in microbiology - Amsterdam [u.a.]: Elsevier Science, Bd. 25 (2017), 4, S. 316-328
NF[kappa]B signaling in gastric cancer
Sokolova, Olga; Naumann, Michael
In: Toxins - Basel : MDPI - Bd. 9.2017, 4, Art.-Nr. 119, insges. 21 S.
NEMO links nuclear factor-[kappa]B to human diseases
Maubach, Gunter; Naumann, Michael
In: Trends in molecular medicine - Amsterdam [u.a.]: Elsevier Science, 2001, Bd. 23.2017, 12, S. 1138-1155
2016
Abstract
NF-KappaB dependent expression of a20 controls cell death in H. pylori-infected cells
Lim, Michelle Chin Chia; Maubach, Gunter; Diezko, Rolf Christian; Sokolova, Olga; Feige, Michael; Buchbinder, Jörn; Lavrik, Inna N.; Naumann, Michael
In: Helicobacter - Oxford [u.a.] : Wiley-Blackwell - Bd. 21.2016, Suppl. 1, Abs. P09.03, S. 162
Begutachteter Zeitschriftenartikel
Pathogenesis of Helicobacter pylori infection
Backert, Steffen; Neddermann, Matthias; Maubach, Gunter; Naumann, Michael
In: Helicobacter - Oxford [u.a.]: Wiley-Blackwell, 1996, Bd. 21 (2016), Suppl.1, Seite 19-25
Proteome rearrangements after auditory learning - high-resolution profiling of synapse-enriched protein fractions from mouse brain
Kähne, Thilo; Richter, Sandra; Kolodziej, Angela; Smalla, Karl-Heinz; Pielot, Rainer; Engler, Alexander; Ohl, Frank W.; Dieterich, Daniela C.; Seidenbecher, Constanze; Tischmeyer, Wolfgang; Naumann, Michael; Gundelfinger, Eckart D.
In: Journal of neurochemistry - Oxford : Wiley-Blackwell, Bd. 138 (2016), Heft 1, S. 124-138
New insights into the mechanism of COP9 signalosomecullin-RING ubiquitin-ligase pathway deregulation in urological cancers
Gummlich, Linda; Kähne, Thilo; Naumann, Michael; Kilic, Ergin; Jung, Klaus; Dubiel, Wolfgang
In: International review of cell and molecular biology - Amsterdam [u.a.]: Elsevier, Bd. 323 (2016), S. 181-229
Molecular architecture of the DED chains at the DISC - regulation of procaspase-8 activation by short DED proteins c-FLIP and procaspase-8 prodomain
Schleich, Kolja; Buchbinder, Jörn Holger; Pietkiewicz, Sabine; Kähne, Thilo; Warnken, Uwe; Öztürk, Selcen; Schnölzer, Martina; Naumann, Michael; Krammer, Peter H.; Lavrik, Inna N.
In: Cell death and differentiation - Houndmills, Basingstoke : Nature Publishing Group, Bd. 23 (2016), Heft 4, S. 681-694
Receptor-interacting protein kinase-2 inhibition by CYLD impairs antibacterial immune responses in macrophages
Wex, Katharina; Schmid, Ursula; Just, Sissy; Wang, Xu; Wurm, Rebecca; Naumann, Michael; Schlüter, Dirk; Nishanth, Gopala
In: Frontiers in immunology - Lausanne: Frontiers Media, 2010, Bd. 6.2016, Art.-Nr. 650, insges. 13 S.
p97/VCP promotes Cullin-RING-ubiquitin-ligase/proteasome-dependent degradation of IBα and the preceding liberation of RelA from ubiquitinated IBα
Schweitzer, Katrin; Pralow, Alexander; Naumann, Michael
In: Journal of cellular and molecular medicine: an international journal ; JCMM - Hoboken, NJ: Wiley-Blackwell, 2000, Bd. 20 (2016), 1, S. 58-70
A20 curtails primary but augments secondary CD8+ T cell responses in intracellular bacterial infection
Just, Sissy; Nishanth, Gopala; Buchbinder, Jörn Holger; Wang, Xu; Naumann, Michael; Lavrik, Inna N.; Schlüter, Dirk
In: Scientific reports - [London] : Macmillan Publishers Limited, part of Springer Nature - Bd. 6.2016, Art.-Nr. 39796, insges. 15 S.
Immunoproteasome induction is suppressed in hepatitis C virus-infected cells in a protein kinase R-dependent manner
Oh, In Soo; Textoris-Taube, Kathrin; Sung, Pil Soo; Kang, Wonseok; Gorny, Xenia; Kähne, Thilo; Hong, Seon-Hui; Choi, Young Joon; Cammann, Clemens; Naumann, Michael; Kim, Jong Hoon; Park, Su-Hyung; Yoo, Ook Joon; Kloetzel, Peter M.; Seifert, Ulrike; Shin, Eui-Cheol
In: Experimental & molecular medicine - [London] : Macmillan Publishers Limited, part of Springer Nature - Bd. 48.2016, Art.-Nr. e270, insges. 10 S.
High resolution quantitative synaptic proteome profiling of mouse brain regions after auditory discrimination learning. Video article
Kolodziej, Angela; Smalla, Karl-Heinz; Richter, Sandra; Engler, Alexander; Pielot, Rainer; Dieterich, Daniela C.; Tischmeyer, Wolfgang; Naumann, Michael; Kähne, Thilo
In: JoVE - [S.l.], 2006, 2016, 118, Art.-Nr. e54992, insges. 12 S.
Receptor-interacting protein kinase-2 inhibition by CYLD impairs antibacterial immune responses in macrophages
Wex, Katharina; Schmid, Ursula; Just, Sissy; Wang, Xu; Wurm, Rebecca; Naumann, Michael; Schlüter, Dirk; Nishanth, Gopala
In: Frontiers in immunology. - Lausanne : Frontiers Media; Bd. 6.2016, Art.-Nr. 650, insges. 13 S.
2015
Abstract
The role of Helicobacter pylori-induced canonical- and non-canonical NF-KB signaling in cell survival
Naumann, Michael; Feige, Michael; Sokolova, Olga
In: Helicobacter - Oxford [u.a.]: Wiley-Blackwell, Bd. 20.2015, Suppl. 1, Abs. P04.18, S. 108-109
Begutachteter Zeitschriftenartikel
A20 expression in dendritic cells protects mice from LPS-induced mortality
Nguyen, Thi-Xuan; Wang, Xu; Nishanth, Gopala; Waisman, Ari; Borucki, Katrin; Isermann, Berend; Naumann, Michael; Deckert, Martina; Schlüter, Dirk
In: European journal of immunology - Weinheim: Wiley-VCH, Bd. 45 (2015), 3, S. 818-828
Quantification of CD95-induced apoptosis and NF-[Kappa]B activation at the single cell level
Schmidt, Jörn H.; Pietkiewicz, Sabine; Naumann, Michael; Lavrik, Inna N.
In: Journal of immunological methods: JIM - Amsterdam [u.a.]: Elsevier Science, Bd. 423 (2015), S. 12-17
Diversity of COP9 signalosome structures and functional consequences
Dubiel, Dawadschargal; Rockel, Beate; Naumann, Michael; Dubiel, Wolfgang
In: FEBS letters: for the rapid publication of short reports in biochemistry, biophysics, and molecular biology/ Vereinigung der Europäischen Biochemischen Gesellschaften - Chichester: Wiley, Bd. 589.2015, 19 Pt.A, S. 2507-2513
CSN-associated USP48 confers stability to nuclear NF-[kappa]B/RelA by trimming K48-linked Ub-chains
Schweitzer, Katrin; Naumann, Michael
In: Biochimica et biophysica acta / Molecular cell research: BBA - Amsterdam [u.a.]: Elsevier, Bd. 1853 (2015), 2, S. 453-469
DNA-dependent protein kinase (DNA-PK) permits vascular smooth muscle cell proliferation through phosphorylation of the orphan nuclear receptor NOR1
Medunjanin, Senad; Daniel, Jan-Marcus; Weinert, Sönke; Dutzmann, Jochen; Burgbacher, Frank; Brecht, Sarah; Brümmer, Dennis; Kähne, Thilo; Naumann, Michael; Sedding, Daniel; Zuschratter, Werner; Braun-Dullaeus, Ruediger C.
In: Cardiovascular research - Oxford: Oxford University Press, Bd. 106 (2015), 3, S. 488-497
Role of calprotectin as a modulator of the IL27-mediated proinflammatory effect on endothelial cells
Dorosz, Susann A.; Ginolhac, Aurélien; Kähne, Thilo; Naumann, Michael; Sauter, Thomas; Salsmann, Alexandre; Bueb, Jean-Luc
In: Mediators of inflammation - Sylvania, Ohio: Hindawi Publishing Corp., 2015, Art.-ID 737310, insges. 16 S.
Differential effects of dopamine signalling on long-term memory formation and consolidation in rodent brain
Reichenbach, Nicole; Herrmann, Ulrike; Kähne, Thilo; Schicknick, Horst; Pielot, Rainer; Naumann, Michael; Dieterich, Daniela C.; Gundelfinger, Eckart D.; Smalla, Karl-Heinz; Tischmeyer, Wolfgang
In: Proteome science - London: BioMed Central, 2003, Bd. 13.2015, Art.-Nr.13, insges. 17 S.
CAND1 exchange factor promotes Keap1 integration into cullin 3-RING ubiquitin ligase during adipogenesis
Dubiel, Dawadschargal; Ordemann, Jürgen; Pratschke, Johann; Dubiel, Wolfgang; Naumann, Michael
In: International journal of biochemistry & cell biology - Amsterdam: Elsevier, Bd. 66 (2015), S. 95-100
Protective dendritic cell responses against listeriosis induced by the short form of the deubiquitinating enzyme CYLD are inhibited by full-length CYLD
Wurm, Rebecca; Just, Sissy; Wang, Xu; Wex, Katharina; Schmid, Ursula; Blanchard, Nicolas; Waisman, Ari; Schild, Hans-Jörg; Naumann, Michael; Schlüter, Dirk; Nishanth, Gopala
In: European journal of immunology - Weinheim: Wiley-VCH, Bd. 45 (2015), 5, S. 1366-1376
Structural modeling of the N-terminal signal-receiving domain of I[kappa]B[alpha]
Yazdi, Samira; Durdagi, Serdar; Naumann, Michael; Stein, Matthias
In: Frontiers in molecular biosciences - Lausanne: Frontiers, Bd. 2.2015, Art.-Nr. 32, insges. 16 S.
2014
Abstract
JAK2V617F mutation is sufficient for autocrine induction of IP-10 in hematopoietic cells
Schnöder, Tina; Pandey, Akhilesh Datt; Nimmagadda, Subbaiah Chery; Wang, Xu; Maubach, Gunter; Wolleschak, Denise; Naumann, Michael; Schlüter, Dirk; Lane, Steven W.; Mullally, Ann; Heidel, Florian; Fischer, Thomas
In: Oncology research and treatment - Basel: Karger, Bd. 37.2014, Suppl. 5, V618, S. 199
Begutachteter Zeitschriftenartikel
MEKK3 and TAK1 synergize to activate IKK complex in Helicobacter pylori infection
Sokolova, Olga; Maubach, Gunter; Naumann, Michael
In: Biochimica et biophysica acta / Molecular cell research: BBA - Amsterdam [u.a.]: Elsevier, Bd. 1843 (2014), 4, S. 715-724
Experimental design, validation and computational modeling uncover DNA damage sensing by DNA-PK and ATM
Flassig, Robert J.; Maubach, Gunter; Täger, Christian; Sundmacher, Kai; Naumann, Michael
In: Molecular BioSystems - Cambridge: Royal Society of Chemistry, 2005, Bd. 10.2014, 7, S. 1978-1986
Helicobacter pylori promotes eukaryotic protein translation by activating phosphatidylinositol 3 kinase/mTOR
Sokolova, Olga; Vieth, Michael; Gnad, Thorsten; Bozko, Przemyslaw M.; Naumann, Michael
In: International journal of biochemistry & cell biology - Amsterdam: Elsevier, Bd. 55 (2014), S. 157-163
Dissertation
Molekulare Charakterisierung der Interaktion des COP9-Signalosoms mit NF-[Kappa]B/RelA und I[Kappa]Bα
Borgmann, Marc; Naumann, Michael
In: Magdeburg, Univ., Fak. für Naturwiss., Diss., 2014, 102 Bl., graph. Darst.
2013
Begutachteter Zeitschriftenartikel
Helicobacter pylori induces type 4 secretion system-dependent, but CagA-independent activation of I[kappa]Bs and NF-[kappa]B/RelA at early time points
Sokolova, Olga; Borgmann, Marc; Rieke, Cornelia; Schweitzer, Katrin; Rothkötter, Hermann-Josef; Naumann, Michael
In: International journal of medical microbiology - München: Elsevier, Bd. 303 (2013), 8, S. 548-552
Crystal structure and versatile functional roles of the COP9 signalosome subunit 1
Lee, Jung-Hoon; Yi, Lina; Li, Jixi; Schweitzer, Katrin; Borgmann, Marc; Naumann, Michael; Wu, Hao
In: Proceedings of the National Academy of Sciences of the United States of America: PNAS/ National Academy of Sciences - Washington, DC: NAS, 1877, Bd. 110.2013, 29, S. 11845-11850
Ca2+/calmodulin-dependent kinase II contributes to inhibitor of nuclear factor-kappa B kinase complex activation in Helicobacter pylori infection
Maubach, Gunter; Sokolova, Olga; Wolfien, Markus; Rothkötter, Hermann-Josef; Naumann, Michael
In: International journal of cancer. - Malden, Mass : Wiley-Blackwell, Bd. 133.2013, 6, S. 1507-1512
Encoding and transducing the synaptic or extrasynaptic origin of NMDA receptor signals to the nucleus
Karpova, Anna; Mikhaylova, Marina G.; Bera, Sujoy; Bär, Julia; Reddy, Pasham Parameshwar; Behnisch, Thomas; Rankovic, Vladan; Spilker, Christina; Bethge, Philipp; Şahin, Jale; Kaushik, Rahul; Zuschratter, Werner; Kähne, Thilo; Naumann, Michael; Gundelfinger, Eckart D.; Kreutz, Michael R.
In: Cell - Cambridge, Mass.: Cell Press, Bd. 152 (2013), 5, S. 1119-1133
CAND1-dependent control of cullin 1-RING Ub ligases is essential for adipogenesis
Dubiel, Dawadschargal; Gierisch, Maria Elka; Huang, Xiaohua; Dubiel, Wolfgang; Naumann, Michael
In: Biochimica et biophysica acta: BBA ; international journal of biochemistry, biophysics and molecular biology - Amsterdam [u.a.]: Elsevier, Bd. 1833 (2013), 5, S. 1078-1084
Rapid interaction of Helicobacter pylori with microvilli of the polar human gastric epithelial cell line NCI-N87
Diesing, Anne-Kathrin; Nossol, Constanze; Faber-Zuschratter, Heidi; Zuschratter, Werner; Renner, Lydia; Sokolova, Olga; Naumann, Michael; Rothkötter, Hermann-Josef
In: The anatomical record: AR ; advances in integrative anatomy and evolutionary biology ; an official publication of the American Association of Anatomists - Hoboken, NJ: Wiley-Liss, 2007, Bd. 296.2013, 12, S. C1
Protein kinase C isozymes regulate matrix metalloproteinase-1 expression and cell invasion in Helicobacter pylori infection
Sokolova, Olga; Vieth, Michael; Naumann, Michael
In: Gut. - London : BMJ Publishing Group, Bd. 62.2013, 3, S. 358-367
Rapid interaction of Helicobacter pylori with microvilli of the polar human gastric epithelial cell line NCI-N87
Diesing, Anne-Kathrin; Nossol, Constanze; Faber-Zuschratter, Heidi; Zuschratter, Werner; Renner, Lydia; Sokolova, Olga; Naumann, Michael; Rothkötter, Hermann-Josef
In: The anatomical record: AR ; advances in integrative anatomy and evolutionary biology ; an official publication of the American Association of Anatomists - Hoboken, NJ: Wiley-Liss, 2007, Bd. 296.2013, 12, S. 1800-1805
Astrocytic A20 ameliorates experimental autoimmune encephalomyelitis by inhibiting NF-[kappa]B- and STAT1-dependent chemokine production in astrocytes
Wang, Xu; Deckert, Martina; Nguyen, Thi-Xuan; Nishanth, Gopala; Just, Sissy; Waisman, Ari; Naumann, Michael; Schlüter, Dirk
In: Acta neuropathologica - Berlin: Springer, 1961, Bd. 126.2013, 5, S. 711-724
Originalartikel in begutachteter internationaler Zeitschrift
CYLD enhances severe listeriosis by impairing IL-6/STAT3-dependent fibrin production
Nishanth, Gopala; Deckert, Martina; Wex, Katharina; Massoumi, Ramin; Schweitzer, Katrin; Naumann, Michael; Schlüter, Dirk
In: PLoS pathogens/ Public Library of Science - Lawrence, Kan.: PLoS, Bd. 9.2013, 6, Art. e1003455, insges. 17 S.
2012
Originalartikel in begutachteter internationaler Zeitschrift
Synaptic proteome changes in mouse brain regions upon auditory discrimination learning
Kähne, Thilo; Kolodziej, Angela; Smalla, Karl-Heinz; Eisenschmidt, Elke; Haus, Utz-Uwe; Weismantel, Robert; Kropf, Siegfried; Wetzel, Wolfram; Ohl, Frank W.; Tischmeyer, Wolfgang; Naumann, Michael; Gundelfinger, Eckart D.
In: Proteomics: proteomics and systems biology - Weinheim: Wiley-VCH, Bd. 12 (2012), 15/16, S. 2433-2444
Cyclin-dependent kinase 6 phosphorylates NF-[kappa]B p65 at serine 536 and contributes to the regulation of inflammatory gene expression
Buss, Holger; Handschick, Katja; Jurrmann, Nadine; Pekkonen, Pirita; Beuerlein, Knut; Müller, Helmut; Wait, Robin; Saklatvala, Jeremy; Ojala, Päivi M.; Schmitz, M. Lienhard; Naumann, Michael; Kracht, Michael
In: PLOS ONE - San Francisco, California, US: PLOS, Bd. 7.2012, 12, Art. e51847, insges. 13 S.
2011
Originalartikel in begutachteter internationaler Zeitschrift
Helicobacter pylori-induced tyrosine phosphorylation of IKK[beta] contributes to NF-[kappa]B activation
Rieke, Cornelia; Papendieck, Anja; Sokolova, Olga; Naumann, Michael
In: Biological chemistry - Berlin [u.a.] : de Gruyter, Bd. 392 (2011), Heft 4, S. 387-393
Microbial-induced immunomodulation by targeting the NF-[Kappa]B system
Neish, Andrew S.; Naumann, Michael
In: Trends in microbiology - Cambridge, Mass. : Cell Press, Bd. 19 (2011), Heft 12, S. 596-605
Nicht begutachteter Zeitschriftenartikel
Therapierelevante Forschung in der Inneren Medizin
Naumann, Michael
In: Ärzteblatt Sachsen-Anhalt - Magdeburg : Ärztekammer Sachsen-Anhalt, Bd. 22 (2011), Heft 4, S. 25-26
2010
Originalartikel in begutachteter internationaler Zeitschrift
Dynamics of bionanoparticle targeting in mixtures of human tumour cells by validated population balance modelling
Rollié, Sascha; Lendeckel, Uwe; Naumann, Michael; Reichl, Udo; Sundmacher, Kai
In: Soft matter / publ. by the Royal Society of Chemistry - Cambridge: RSC Publ., 2005, Bd. 6.2010, 6, S. 1203-1216
What a disorder: proinflammatory signaling pathways induced by Helicobacter pylori
Backert, Steffen; Naumann, Michael
In: Trends in microbiology - Cambridge, Mass. : Cell Press, Bd. 18 (2010), Heft 11, S. 479-486
Helicobacter pylori-induced activation of [beta]-catenin involves low density lipoprotein receptor-related protein 6 and dishevelled
Gnad, Thorsten; Feoktistova, Maria; Leverkus, Martin; Lendeckel, Uwe; Naumann, Michael
In: Molecular cancer . - London : Biomed Central, Bd. 9.2010, 31, insges. 9 S.; Abstract
Helicobacter pylori induces NF-[kappa]B independent of CagA. Correspondence
Schweitzer, Katrin; Sokolova, Olga; Bozko, Przemyslaw M.; Naumann, Michael
In: EMBO reports / European Molecular Biology Organization - Weinheim : Wiley, Bd. 11 (2010), Heft 1, S. 10-11
Interleukin 1 beta (IL1B) gene polymorphisms are not associated with gastric carcinogenesis in Germany
Wex, Thomas; Leodolter, Andreas; Bornschein, Jan; Küster, Dörthe; Kähne, Thilo; Kropf, Siegfried; Albrecht, Caroline; Naumann, Michael; Roessner, Albert; Malfertheiner, Peter
In: Anticancer research . - Kapandriti : International Inst. of Anticancer Research, Bd. 30.2010, 2, S. 505-511
Non-T cell activation linker regulates ERK activation in Helicobacter pylori-infected epithelial cells
Rieke, Cornelia; Kähne, Thilo; Schweitzer, Katrin; Schraven, Burkhart; Wienands, Jürgen; Engelke, Michael; Naumann, Michael
In: Cellular signalling - Amsterdam : Elsevier, Bd. 22 (2010), Heft 3, S. 395-403
Novel plant metalloproteinase from Dieffenbachia seguine causes fingertip necrosis. Correspondence
Mirastschijski, Ursula; Schnabel, Reinhild; Naumann, Michael; Kähne, Thilo
In: The British journal of dermatology - Oxford : Wiley-Blackwell, Bd. 162 (2010), Heft 5, S. 1150-1152
Control of NF-[kappa]B activation by the COP9 signalosome
Schweitzer, Katrin; Naumann, Michael
In: Biochemical Society transactions - London : Portland Press, Bd. 38 (2010), Heft 1, S. 156-161
Disposable micro-fluidic biosensor array for online parallelized cell adhesion kinetics analysis on quartz crystal resonators
Cama, Gianluca; Jacobs, Thomas; Dimaki, Maria I.; Svendsen, Winnie E.; Hauptmann, Peter; Naumann, Michael
In: Measurement science and technology . - Bristol : IOP Publ. Ltd., Bd. 21.2010, 8, insges. 12 S.
Protective toxoplasma gondii-specific T-cell responses require T-cell-specific expression of protein kinase C-theta
Nishanth, Gopala; Sakowicz-Burkiewicz, Monika; Händel, Ulrike; Kliche, Stefanie; Wang, Xiaoqian; Naumann, Michael; Deckert, Martina; Schlüter, Dirk
In: Infection and immunity: IAI ; a publication of the American Society for Microbiology - Washington, DC: Soc., Bd. 78 (2010), 8, S. 3454-3464
Studies on neuronal differentiation and signalling processes with a novel impedimetric biosensor
Valero, Teresa; Moschopoulou, Georgia; Kintzios, Spiridon; Hauptmann, Peter; Naumann, Michael; Jacobs, Thomas
In: Biosensors & bioelectronics - Barking, Essex : Elsevier, Bd. 26 (2010), Heft 4, S. 1407-1413
2009
Originalartikel in begutachteter internationaler Zeitschrift
Logical network of genotoxic stress-induced NF-[kappa]B signal transduction predicts putative target structures for therapeutic intervention strategies
Poltz, Rainer; Franke, Raimo Michael; Schweitzer, Katrin; Klamt, Steffen; Gilles, Ernst Dieter; Naumann, Michael
In: Advances and applications in bioinformatics and chemistry - Albany, Auckland: Dove Medical Press, Bd. 2 (2009), S. 125-138
Influence of statistical variations in cell distribution on the proliferation kinetics of Madin-Darby canine kidney cells on quartz crystal resonator
Cama, Gianluca; Bolaeva, Kermen; Jacobs, Thomas; Hartmann, Matthias; Hirsch, Sören; Naumann, Michael; Hauptmann, Peter
In: Procedia chemistry - Amsterdam [u.a.] : Elsevier, Bd. 1 (2009), Heft 1, S. 373-376 [Proceedings of the Eurosensors XXIII Conference]
Identification of novel Cyclooxygenase-2-dependent genes in Helicobacter pylori infection in vivo
Walduck, Anna K.; Weber, Matthias; Wunder, Christian; Jüttner, Stefan; Stolte, Manfred; Vieth, Michael; Wiedenmann, Bertram; Meyer, Thomas F.; Naumann, Michael; Höcker, Michael
In: Molecular cancer . - London : Biomed Central, Bd. 8.2009, 22, insges. 13 S.; Abstract
COP9 signalosome controls the Carma1-Bcl10-Malt1 complex upon T-cell stimulation
Welteke, Verena; Eitelhuber, Andrea; Düwel, Michael; Schweitzer, Katrin; Naumann, Michael; Krappmann, Daniel
In: EMBO reports / European Molecular Biology Organization - Weinheim : Wiley, Bd. 10 (2009), Heft 6, S. 642-648
Impact of flow-through regime on the cultivation of epithelial cells on quartz crystal resonators in micro fluidic channels
Jacobs, Thomas; Cama, Gianluca; Bolaeva, Kermen; Naumann, Michael; Hauptmann, Peter
In: Procedia chemistry - Amsterdam [u.a.] : Elsevier, Bd. 1 (2009), Heft 1, S. 365-368 [Proceedings of the Eurosensors XXIII Conference]
Electrical impedance spectroscopy of gel embedded neuronal cells based on a novel impedimetric biosensor
Jacobs, Thomas; Valero, Teresa; Naumann, Michael; Kintzios, Spiridon; Hauptmann, Peter
In: Procedia chemistry - Amsterdam [u.a.] : Elsevier, Bd. 1 (2009), Heft 1, S. 261-264 [Proceedings of the Eurosensors XXIII Conference]
Ectodomain shedding of E-cadherin and c-Met is induced by Helicobacter pylori infection
Schirrmeister, Wiebke; Gnad, Thorsten; Wex, Thomas; Higashiyama, Shigeki; Wolke, Carmen; Naumann, Michael; Lendeckel, Uwe
In: Experimental cell research - San Diego, Calif. : Elsevier, Bd. 315 (2009), Heft 20, S. 3500-3508
Electrical impedance analysis of N2a neuroblastoma cells in gel matrices after ACh-receptor triggering with an impedimetric biosensor
Valero, Teresa; Jacobs, Thomas; Moschopoulou, Georgia; Naumann, Michael; Hauptmann, Peter; Kintzios, Spiridon
In: Procedia chemistry - Amsterdam [u.a.] : Elsevier, Bd. 1 (2009), Heft 1, S. 734-737 [Proceedings of the Eurosensors XXIII Conference]
Bis(1H-indol-2-yl)methanones are effective inhibitors of FLT3-ITD tyrosine kinase and partially overcome resistance to PKC412A in vitro
Heidel, Florian; Lipka, Daniel; Mirea, Fian K.; Mahboobi, Siavosh; Grundler, Rebekka; Kancha, Rama K.; Duyster, Justus; Naumann, Michael; Huber, Christoph; Böhmer, Frank D.; Fischer, Thomas
In: British journal of haematology - Oxford [u.a.] : Wiley-Blackwell, Bd. 144 (2009), Heft 6, S. 865-874
Originalartikel in begutachteter zeitschriftenartiger Reihe
Impedimetric biosensor system for the on-line analysis of stimulated neuronal cells embedded in gel matrices
Jacobs, Thomas; Valero, Teresa; Naumann, Michael; Kintzios, Spiridon; Hauptmann, Peter
In: IEEE Sensors 2009 . - IEEE, ISBN 978-1-424-45335-1, S. 1864-1867Kongress: IEEE Conference on Sensors; 8 (Christchurch) : 2009.10.25-28[Auch auf CD-ROM erschienen]
2008
Originalartikel in begutachteter internationaler Zeitschrift
Protein kinase C-[theta] critically regulates the proliferation and survival of pathogen-specific T cells in murine listeriosis
Sakowicz-Burkiewicz, Monika; Nishanth, Gopala; Helmuth, Ulrike; Drögemüller, Katrin; Busch, Dirk H.; Utermöhlen, Olaf; Naumann, Michael; Deckert, Martina; Schlüter, Dirk
In: The journal of immunology: official journal of the American Association of Immunologists - Rockville, Md.: American Association of Immunologists, 1916, Bd. 180.2008, 8, S. 5601-5612
Helicobacter pylori regulates p21WAF1 by histone H4 acetylation
Xia, Guoqing; Schneider-Stock, Regine; Diestel, Antje; Habold, Caroline; Krüger, Sabine; Roessner, Albert; Naumann, Michael; Lendeckel, Uwe
In: Biochemical and biophysical research communications - San Diego, Calif. : Elsevier, Bd. 369 (2008), Heft 2, S. 526-531
Helicobacter pylori suppresses glycogen synthase kinase 3[beta] to promote [beta]-catenin activity
Sokolova, Olga; Bozko, Przemyslaw M.; Naumann, Michael
In: The journal of biological chemistry - Bethesda, Md. : ASBMB, Bd. 283 (2008), Heft 43, S. 29367-29374
Host-pathogen systems biology: logical modelling of hepatocyte growth factor and Helicobacter pylori induced c-Met signal transduction
Franke, Raimo; Müller, Melanie; Wundrack, Nicole; Gilles, Ernst-Dieter; Klamt, Steffen; Kähne, Thilo; Naumann, Michael
In: BMC systems biology . - London : BioMed Central, Bd. 2.2008, 4, insges. 17 S.; Abstract
Originalartikel in begutachteter zeitschriftenartiger Reihe
Real-time analysis of hepatocyte growth factor induced cell motility with quartz crystal resonators
Jacobs, Thomas; Bolaeva, Kermen; Kähne, Thilo; Naumann, Michael; Hauptmann, Peter
In: IEEE sensors 2008: the 7th IEEE Conference on Sensors ; Lecce, Italy, October 26-29, 2008/ Conference on Sensors, 2008 . - 2008, S. 246-249Kongress: IEEE Conference on Sensors 7 (Lecce, Italy : 2008.10.26-29)[Beitrag auf CD-ROM]
Online adhesion analysis of hepatocyte growth factor stimulated cells with resonant biosensor
Jacobs, Thomas; Bolaeva, Kermen; Kähne, Thilo; Naumann, Michael; Hauptmann, Peter
In: Proceedings: Dresden, Germany, 7 - 10 September 2008 - Düsseldorf: VDI/VDE-Ges. Mess- und Automatisierungstechnik, 2008 . - 2008, S. 1185-1188Kongress: Eurosensors 22 (Dresden : 2008.09.07-10)[Beitrag auf CD-ROM]
Disposable micro fluidic biosensor array for parallelized online cell stimulation analysis
Jacobs, Thomas; Cama, Gianluca; Hartmann, Matthias; Kähne, Thilo; Hirsch, Sören; Naumann, Michael; Hauptmann, Peter
In: Proceedings: Dresden, Germany, 7 - 10 September 2008 - Düsseldorf: VDI/VDE-Ges. Mess- und Automatisierungstechnik, 2008 . - 2008, S. 1189-1192Kongress: Eurosensors 22 (Dresden : 2008.09.07-10)[Beitrag auf CD-ROM]
Micro fluidic biosensor array for parallelized cell adhesion analysis during pathogenic infection
Jacobs, Thomas; Cama, Gianluca; Hartmann, Matthias; Kähne, Thilo; Hirsch, Sören; Naumann, Michael; Hauptmann, Peter
In: IEEE sensors 2008: the 7th IEEE Conference on Sensors ; Lecce, Italy, October 26-29, 2008/ Conference on Sensors, 2008 . - 2008, S. 1460-1463Kongress: IEEE Conference on Sensors 7 (Lecce, Italy : 2008.10.26-29)[Beitrag auf CD-ROM]
2007
Buchbeitrag
Expression of ADAM19 in Helicobacter pylori-mediated diseases and gastric cancer
Wex, Thomas; Sokic-Milutinovic, Aleksandra; Kalinski, Thomas; Roessner, Albert; Malfertheiner, Peter; Naumann, Michael; Lendeckel, Uwe
In: Gastric cancer research trends - New York: Nova Science . - 2007, S. 171-188
Originalartikel in begutachteter internationaler Zeitschrift
Cholera toxin promotes the generation of semi-mature porcine monocyte-derived dendritic cells that are unable to stimulate T cells
Bimczok, Diane; Rau, Henriette; Wundrack, Nicole; Naumann, Michael; Rothkötter, Hermann-Josef; McCullough, Kenneth; Summerfield, Artur
In: Veterinary research - Paris : Ed.Scientifiques Elsevier, Bd. 38 (2007), Heft 4, S. 597-612
The Fusarium toxin deoxynivalenol disrupts phenotype and function of monocyte-derived dendritic cells in vivo and in vitro
Bimczok, Diane; Döll, Susanne; Rau, Henriette; Goyarts, Tanja; Wundrack, Nicole; Naumann, Michael; Dänicke, Sven; Rothkötter, Hermann-Josef
In: Immunobiology - Amsterdam : Elsevier, Bd. 212 (2007), Heft 8, S. 655-666
Beyond I[kappa]Bs: alternative regulation of NF-[kappa]B activity
Neumann, Manfred; Naumann, Michael
In: The FASEB journal / Federation of American Societies for Experimental Biology - Bethesda, Md. : FASEB, Bd. 21 (2007), Heft 11, S. 2642-2654
CSN controls NF-[kappa]B by deubiquitinylation of I[kappa]B[alpha]
Schweitzer, Katrin; Bozko, Przemyslaw M.; Dubiel, Wolfgang; Naumann, Michael
In: The EMBO journal / European Molecular Biology Organization - Heidelberg, Germany : Wiley, Bd. 26 (2007), Heft 6, S. 1532-1541
CSN controls NF-[kappa]B by deubiquitinylation of I[kappa]B[alpha]
Schweitzer, Katrin; Bozko, Przemyslaw M.; Dubiel, Wolfgang; Naumann, Michael
In: The EMBO journal/ European Molecular Biology Organization - Heidelberg, Germany: Wiley, Bd. 26 (2007), 6, S. 1532-1541
Beyond I[kappa]Bs: alternative regulation of NF-[kappa]B activity
Neumann, Manfred; Naumann, Michael
In: The FASEB journal: the official journal of the Federation of American Societies for Experimental Biology/ Federation of American Societies for Experimental Biology - Bethesda, Md.: FASEB, Bd. 21 (2007), 11, S. 2642-2654
Subcellular localization of Grb2 by the adaptor protein Dok-3 restricts the intensity of Ca2+ signaling in B cells
Stork, Björn; Neumann, Konstantin; Goldbeck, Ingo; Alers, Sebastian; Kähne, Thilo; Naumann, Michael; Engelke, Michael; Wienands, Jürgen
In: The EMBO journal/ European Molecular Biology Organization - Heidelberg, Germany: Wiley, Bd. 26 (2007), 4, S. 1140-1149
Cholera toxin promotes the generation of semi-mature porcine monocyte-derived dendritic cells that are unable to stimulate T cells
Bimczok, Diane; Rau, Henriette; Wundrack, Nicole; Naumann, Michael; Rothkötter, Hermann-Josef; McCullough, Kenneth; Summerfield, Artur
In: Veterinary research / Institut National de la Recherche Agronomique - Paris: Ed.Scientifiques Elsevier, Bd. 38 (2007), 4, S. 597-612
Subcellular localization of Grb2 by the adaptor protein Dok-3 restricts the intensity of Ca2+ signaling in B cells
Stork, Björn; Neumann, Konstantin; Goldbeck, Ingo; Alers, Sebastian; Kähne, Thilo; Naumann, Michael; Engelke, Michael; Wienands, Jürgen
In: The EMBO journal / European Molecular Biology Organization - Heidelberg, Germany : Wiley, Bd. 26 (2007), Heft 4, S. 1140-1149
The Fusarium toxin deoxynivalenol disrupts phenotype and function of monocyte-derived dendritic cells in vivo and in vitro
Bimczok, Diane; Döll, Susanne; Rau, Henriette; Goyarts, Tanja; Wundrack, Nicole; Naumann, Michael; Dänicke, Sven; Rothkötter, Hermann-Josef
In: Immunobiology: founded in 1909 - Amsterdam: Elsevier, Bd. 212 (2007), 8, S. 655-666
Control of the NF-[kappa]B inhibitor I[kappa]B[alpha] in pathogen infection
Naumann, Michael
In: Biochemical Society transactions - London : Portland Press, Bd. 35 (2007), Heft 2, S. 267-269
Control of the NF-[kappa]B inhibitor I[kappa]B[alpha] in pathogen infection
Naumann, Michael
In: Biochemical Society transactions/ Biochemical Society - London: Portland Press, Bd. 35 (2007), 2, S. 267-269
Soluble galectin-3 is a strong, colonic epithelial-cell-derived, lamina propria fibroblast-stimulating factor
Lippert, E.; Falk, W.; Bataille, F.; Kähne, Thilo; Naumann, Michael; Goeke, M.; Herfarth, H.; Schoelmerich, J.; Rogler, G.
In: Gut: the journal of the British Society of Gastroenterology ; an international journal of gastroenterology and hepatology / ed. Sheila Sherlock: the journal of the British Society of Gastroenterology ; an international journal of gastroenterology and hepatology - London: BMJ Publishing Group, Bd. 56 (2007), 1, S. 43-51
Originalartikel in begutachteter zeitschriftenartiger Reihe
Micro fluidic biosensor system based on quartz crystal resonators for fast online adherent cell proliferation and stimulation analysis
Jacobs, Thomas; Gomide, Andreza; Kähne, Thilo; Kienle, Achim; Naumann, Michael; Hauptmann, Peter
In: IEEE sensors 2007 conference, 2007 . - 2007, S. 720-723
2006
Originalartikel in begutachteter internationaler Zeitschrift
The PAK1 autoregulatory domain is required for interaction with NIK in Helicobacter pylori-induced NF-[kappa]B activation
Neumann, Manfred; Foryst-Ludwig, Anna; Klar, Stefanie; Schweitzer, Katrin; Naumann, Michael
In: Biological chemistry - Berlin [u.a.] : de Gruyter, Bd. 387 (2006), Heft 1, S. 79-86
The PAK1 autoregulatory domain is required for interaction with NIK in Helicobacter pylori-induced NF-[kappa]B activation
Neumann, Manfred; Foryst-Ludwig, Anna; Klar, Stefanie; Schweitzer, Katrin; Naumann, Michael
In: Biological chemistry - Berlin [u.a.]: de Gruyter, Bd. 387 (2006), 1, S. 79-86
Epithelial cell signaling in Helicobacter pylori infection
Crabtree, Jean E.; Naumann, Michael
In: Current signal transduction therapy . - San Francisco, Calif. [u.a.] : Bentham Science Publ., Bd. 1.2006, 1, S. 53-65
Helicobacter pylori encoding the pathogenicity island activates matrix-metalloproteinase 1 in gastric epithelial cells via JNK and ERK
Krüger, Sabine; Hundertmark, Tanja; Kalinski, Thomas; Peitz, Ulrich; Wex, Thomas; Malfertheiner, Peter; Naumann, Michael; Roessner, Albert
In: The journal of biological chemistry - Bethesda, Md.: ASBMB, Bd. 281 (2006), 5, S. 2868-2875
Helicobacter pylori encoding the pathogenicity island activates matrix-metalloproteinase 1 in gastric epithelial cells via JNK and ERK
Krüger, Sabine; Hundertmark, Tanja; Kalinski, Thomas; Peitz, Ulrich; Wex, Thomas; Malfertheiner, Peter; Naumann, Michael; Roessner, Albert
In: The journal of biological chemistry - Bethesda, Md. : ASBMB, Bd. 281 (2006), Heft 5, S. 2868-2875
2005
Buchbeitrag
Helicobacter pylori mechanisms for inducing epithelial cell proliferation.
Naumann, Michael; Crabtree, J.
In: keine Angabe
Originalartikel in begutachteter internationaler Zeitschrift
Inhibition of RICK/nuclear factor-kappaB and p38 signaling attenuates the inflammatory response in a murine model of Crohn disease.
Hollenbach, Eike; Vieth, Michael W.R.; Roessner, Albert; Neumann, Manfred; Malfertheiner, Peter; Naumann, Michael
In: keine Angabe
Consequences of COP9 signalosome and 26S proteasome interaction.
Huang, X.; Hetfeld, B.; Seifert, U.; Kaehne, Thilo; Kloetzel, P.M.; Naumann, Michael; Bech-Otschir, D.; Dubiel, W.
In: keine Angabe
Pathogenicity island-dependent effects of Helicobacter pylori on intracellular signal transduction in epithelial cells.
Naumann, Michael
In: keine Angabe
Gene transfer of tissue inhibitor of metalloproteinases-3 reverses the inhibitory effects of TNF-alpha on Fas-induced apoptosis in rheumatoid arthritis synovial fibroblasts.
Drynda, Andreas; Quax, P.; Neumann, Manfred; Laan, W.van der; Pap, Geza; Drynda, Susanne; Meinecke, I.; Kekow, Joern; Neumann, W.; Huizinga, T.; Naumann, Michael; Koenig, Wolfgang; Pap, T.
In: J. Immunol. 174(2005), Nr. 10, S. 6524 - 6531
Helicobacter pylori eradication has the potential to prevent gastric cancer : a state-of-the- art critique.
Malfertheiner, Peter; Sipponen, P.; Naumann, Michael; Moayyedi, P.; Megraud, F.; Xiao, S.D.
In: keine Angabe
Up-regulation of cathepsin X in Helicobacter pylori gastritis and gastric cancer.
Krueger, Sabine; Kalinski, Thomas; Hundertmark, Tanja; Wex, Thomas; Kuester, Doerthe; Peitz, Ulrich; Ebert, Matthias; Naegler, D.; Kellner, U.; Malfertheiner, Peter; Naumann, Michael; Roecken, Christoph; Roessner, Albert
In: J. Pathol. 207(2005), Nr. 1, S. 32 - 42
The anti-inflammatory compound curcumin inhibits Neisseria gonorrhoeae-induced NF-kappaB signaling, release of pro-inflammatory cytokines/chemokines and attenuates adhesion in late infection.
Wessler, S.; Muenzner, P.; Meyer, T.; Naumann, Michael
In: keine Angabe
2004
Originalartikel in begutachteter internationaler Zeitschrift
Curcumin blocks NF-kappaB and the motogenic response in Helicobacter pylori-infected epithelial cells.
Foryst-Ludwig, Anna; Neumann, Manfred; Schneider-Brachert, W.; Naumann, Michael
In: keine Angabe
Analysis of the type IV secretion system-dependent cell motility of Helicobacter pylori- infected epithelial cells.
Al-Ghoul, L.; Wessler, Silja; Hundertmark, Tanja; Krueger, Sabine; Fischer, W.; Wunder, C.; Haas, R.; Roessner, Albert; Naumann, Michael
In: keine Angabe
Inhibition of p38 MAP kinase- and RICK/NF-kappaB-signaling suppresses inflammatory bowel disease.
Hollenbach, Eike; Neumann, Manfred; Vieth, Michael W.R.; Roessner, Albert; Malfertheiner, Peter; Naumann, Michael
In: keine Angabe
Prevention of gastric cancer by Helicobacter pylori eradication.
Leodolter, Andreas; Naumann, Michael; Malfertheiner, Peter
In: keine Angabe
Helicobacter pylori-induced epithelial cell signalling in gastric carcinogenesis.
Naumann, Michael; Crabtree, J.
In: keine Angabe
2003
Originalartikel in begutachteter internationaler Zeitschrift
The mitogen-activated protein kinase p38 : a new molecular target for anti-inflammatory therapy in Crohn's disease?.
Hollenbach, Eike; Naumann, Michael; Malfertheiner, Peter
In: keine Angabe
Fission yeast COP9/signalosome suppresses cullin activity through recruitment of the deubiquitylating enzyme Ubp12p.
Zhou, C.; Wee, S.; Rhee, E.; Naumann, Michael; Dubiel, W.; Wolf, D.
In: keine Angabe
Helicobacter pylori stimulates host vascular endothelial growth factor-A (vegf-A) gene expression via MEK/ERK-dependent activation of Sp1 and Sp3. . - Gedr. ersch. in: FASEB J. 18(2004)1, S. 218 - 220.
Strowski, M.; Cramer, T.; Schaefer, G.; Wessler, Silja; Naumann, Michael; Hoecker, M.
In: Faseb J.(2003)
Helicobacter pylori stimulates host cyclooxygenase-2 gene transcription : critical importance of MEK/ERK-dependent activation of USF1/-2 and CREB transcription factors.
Juettner, S.; Cramer, T.; Wessler, Silja; Walduck, A.; Naumann, Michael; Hoecker, M.
In: keine Angabe
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