Publikationen
2026
Begutachteter Zeitschriftenartikel
New avenues for human blood plasma biomarker discovery via improved in-depth analysis of the low-abundant N-glycoproteome
Zuniga-Banuelos, Frania J.; Hoffmann, Marcus; Reichl, Udo; Rapp, Erdmann
In: Engineering - Beijing : Engineering Sciences Press., Bd. 57 (2026), S. 23-42
2025
Begutachteter Zeitschriftenartikel
Quantification of intracellular influenza A virus protein dynamics in different host cells after seed virus adaptation
Küchler, Jan; Opitz, Patricia; Jordan, Ingo; Genzel, Yvonne; Benndorf, Dirk; Reichl, Udo
In: Applied microbiology and biotechnology - Berlin : Springer, Bd. 109 (2025), Artikel 74, insges. 17 S.
Influenza A virus production following quality by design principles
Zinnecker, Tilia; Thiele, Kristin; Schmidberger, Timo; Genzel, Yvonne; Reichl, Udo
In: Engineering in life sciences - Weinheim : Wiley-VCH, Bd. 25 (2025), Heft 4, Artikel e70027, insges. 11 S.
Fecal metaproteomics enables functional characterization of remission in patients with inflammatory bowel disease
Wolf, Maximilian; Lange, Julian; Benndorf, Dirk; Welz, Lina; Nikolaus, Susanna; Siever, Laura Katharina; Tran, Florian; Schallert, Kay; Hellwig, Patrick; Schreiber, Stefan; Gunzer, Matthias; Rosenstiel, Philip; Reichl, Udo; Adolph, Timon; Jukic, Almina; Aden, Konrad; Heyer, Robert
In: Journal of proteomics - New York, NY [u.a.] : Elsevier, Bd. 318 (2025), S. 1-11, Artikel 105455, 1 Online-Ressource (11 Seiten)
Seed train intensification and TFDF-based perfusion for MDCK cell-based influenza a virus production
Zinnecker, Tilia; Wicke, Emelie; Reichl, Udo; Göbel, Sven; Genzel, Yvonne
In: Processes - Basel : MDPI, Bd. 13 (2025), Heft 5, Artikel 1286, insges. 21 S.
Process intensification for recombinant Marburg virus glycoprotein production using drosophila S2 cells
Göbel, Sven; Mayerlen, Ludwig; Eiser, Isabelle Yazel; Fichtmueller, Lisa; Clements, David; Reichl, Udo; Genzel, Yvonne; Lehrer, Axel T.
In: Engineering in life sciences - Weinheim : Wiley-VCH, Bd. 25 (2025), Heft 5, Artikel e70022, insges. 13 S.
High cell density perfusion process of quail cells producing oncolytic rVSV-NDV
Jacobtorweihe, Lennart; Göbel, Sven; Wolschek, Markus; Altomonte, Jennifer; Reichl, Udo; Genzel, Yvonne
In: Engineering in life sciences - Weinheim : Wiley-VCH, Bd. 25 (2025), Heft 7, Artikel e70035, insges. 11 S.
Establishment of a cell-free multi-enzyme cascade for the synthesis of UDP-GalNAc
Hoang, Tuan Son; Wormstall, Sara-Theres; Hoang, Nam-Hai; Reichl, Udo; Rexer, Thomas F. T.
In: New biotechnology - New York, NY [u.a.] : Elsevier, Bd. 89 (2025), S. 20-28
Optimization of YF17D-vectored Zika vaccine production by employing small-molecule viral sensitizers to enhance yields
Göbel, Sven; Zinnecker, Tilia; Jordan, Ingo; Sandig, Volker; Vervoort, Andrea; Jong, de Jondavid; Diallo, Jean-Simon; Satzer, Peter; Satzer, Manfred; Dallmeier, Kai; Reichl, Udo; Genzel, Yvonne
In: Vaccines - Basel : MDPI, Bd. 13 (2025), Heft 7, Artikel 757, insges. 26 S.
Raider of the lost N-glycans - localizing rare and frequently overlooked IgG N-glycans with sulfation or bisecting LacNAc
Burock, Robert; Chuzel, Léa; Kähne, Thilo; Reichl, Udo; Rapp, Erdmann; Hennig, René
In: Frontiers in molecular biosciences - Lausanne : Frontiers, Bd. 12 (2025), Artikel 1593708, insges. 15 S.
Immunoglobulin A carries sulfated and O-acetylated N-glycans primarily at the tailpiece site – strategies for site-specific N-glycan identification
Zuniga-Banuelos, Frania J.; Lemke, Greta; Hoffmann, Marcus; Reichl, Udo; Rapp, Erdmann
In: Frontiers in molecular biosciences - Lausanne : Frontiers, Bd. 12 (2025), Artikel 1595173, insges. 19 S.
Quantitative analysis of proteomic changes in two monoclonal suspension MDCK cell lines infected with human influenza A virus (H1N1)
Küchler, Jan; Zinnecker, Tilia; Hellwig, Patrick; Wolf, Maximilian; Benndorf, Dirk; Genzel, Yvonne; Reichl, Udo
In: PLOS ONE - San Francisco, California, US : PLOS, Bd. 20 (2025), Heft 10, Artikel e0327939, insges. 18 S.
Reconstructing governing equations of influenza virus dynamics from incomplete measurements
Steiger, Martin; Gosea, Ion Victor; Rüdiger, Daniel; Benner, Peter; Brachtendorf, Hans-Georg; Reichl, Udo
In: IFAC-PapersOnLine / Internationale Förderung für Automatische Lenkung - Frankfurt : Elsevier, Bd. 59 (2025), Heft 6, S. 540-545
Dissertation
Genetically engineered defective interfering particles of influenza A virus for antiviral treatment and vaccination
Dogra, Tanya; Reichl, Udo
In: Magdeburg: Universitätsbibliothek, Dissertation Otto-von-Guericke-Universität Magdeburg, Fakultät für Verfahrens- und Systemtechnik 2025, 1 Online-Ressource (165 Blätter, 6,84 MB) [Literaturverzeichnis: Blatt 140-149]
Modeling the dynamics of cell growth, central carbon metabolism and virus production in animal cells
Correia Ramos, João Rodrigues; Reichl, Udo
In: Magdeburg: Universitätsbibliothek, Dissertation Otto-von-Guericke-Universität Magdeburg, Fakultät für Verfahrens- und Systemtechnik 2025, 1 Online-Ressource (XL, 181 Seiten, 8,19 MB) [Literaturangaben]
In-depth N-glycoproteomic analysis of human blood plasma proteins
Zúñiga Bañuelos, Frania Jaqueline; Reichl, Udo
In: Magdeburg: Universitätsbibliothek, Dissertation Otto-von-Guericke-Universität Magdeburg, Fakultät für Verfahrens- und Systemtechnik 2025, 1 Online-Ressource (XIX, 172 Seiten, 12,67 MB) [Literaturverzeichnis: Seite 111-126]
In-Depth N-Glycan analysis using a synergy of glycomics technologies: method development and biomedical applications
Cajic, Samanta; Langermann und Erlencamp, Jan von; Reichl, Udo
In: Barleben: docupoint Verlag, Dissertation Otto-von-Guericke-Universität Magdeburg, Fakultät für Verfahrens- und Systemtechnik 2025, XXIII, 197 Seiten, ISBN: 978-3-86912-223-6 [Literaturverzeichnis: Seite 123-144]
Buchbeitrag
Molecular community data meets Anaerobic Digestion Model 1 (ADM1) - a study about the correlation between metagenome-centric metaproteomics data of a two-step full-scale anaerobic digester and its corresponding mathematical model
Hellwig, Patrick; Seick, Ingolf; Meinusch, Nicole; Benndorf, Dirk; Wiese, Jürgen; Reichl, Udo; Heyer, Robert
In: Water research - Amsterdam [u.a.] : Elsevier Science, Bd. 292 (2025), Artikel 125272, insges. 15 S.
2024
Begutachteter Zeitschriftenartikel
Breakdown of hardly degradable carbohydrates (lignocellulose) in a two-stage anaerobic digestion plant is favored in the main fermenter
Heyer, Robert; Hellwig, Patrick; Maus, Irena; Walke, Danile; Schlüter, Andreas; Hassa, Julia; Sczyrba, Alexander; Tubbesing, Tom; Klocke, Michael; Mächtig, Torsten; Schallert, Kay; Seick, Ingolf; Reichl, Udo; Benndorf, Dirk
In: Water research - Amsterdam [u.a.] : Elsevier Science, Bd. 250 (2024), Artikel 121020, insges. 11 S.
Model-based optimization of cell-free enzyme cascades exemplified for the production of GDP-fucose
Huber, Nicolas; Alcalá-Orozco, Edgar Alberto; Rexer, Thomas; Reichl, Udo; Klamt, Steffen
In: Metabolic engineering - Orlando, Fla. : Academic Press, Bd. 81 (2024), S. 10-25
From single-cell cloning to high-yield influenza virus production - implementing advanced technologies in vaccine process development
Zinnecker, Tilia; Badri, Najd; Araujo, Diogo; Thiele, Kristin; Reichl, Udo; Genzel, Yvonne
In: Engineering in life sciences - Weinheim : Wiley-VCH, Bd. 24 (2024), Heft 4, Artikel 2300245
Production of recombinant vesicular stomatitis virus-based vectors by tangential flow depth filtration
Göbel, Sven; Pelz, Lars; Silva, Cristina A. T.; Brühlmann, Béla; Hill, Charles; Altomonte, Jennifer; Kamen, Amine; Reichl, Udo; Genzel, Yvonne
In: Applied microbiology and biotechnology - Berlin : Springer, Bd. 108 (2024), Artikel 240, insges. 18 S.
Mathematical model calibrated to in vitro data predicts mechanisms of antiviral action of the influenza defective interfering particle "OP7"
Rüdiger, Daniel; Piasecka, Julita; Küchler, Jan; Pontes, Carolina; Laske, Tanja; Kupke, Sascha Y.; Reichl, Udo
In: iScience - Amsterdam : Elsevier, Bd. 27 (2024), Heft 4, Artikel 109421, insges. 22 S.
Macrophage- and CD4+ T cell-derived SIV differ in glycosylation, infectivity and neutralization sensitivity
Karsten, Christina B.; Büttner, Falk; Cajic, Samanta; Nehlmeier, Inga; Roshani, Berit; Klippert, Antonina; Sauermann, Ulrike; Stolte-Leeb, Nicole; Reichl, Udo; Gerardy-Schahn, Rita; Rapp, Erdmann; Stahl-Hennig, Christine
In: PLoS pathogens / Public Library of Science - Lawrence, Kan. : PLoS, Bd. 20 (2024), Heft 5, Artikel e1012190, insges. 20 S.
Parallel multifactorial process optimization and intensification for high-yield production of Live YF17D-vectored zika vaccine
Göbel, Sven; Kazemi, Ozeir; Ma, Ji; Jordan, Ingo; Sandig, Volker; Paulissen, Jasmine; Kerstens, Winnie; Thibaut, Hendrik Jan; Reichl, Udo; Dallmeier, Kai; Genzel, Yvonne
In: Vaccines - Basel : MDPI, Bd. 12 (2024), Heft 7, Artikel 755, insges. 23 S.
Innovations in cell culture-based influenza vaccine manufacturing – from static cultures to high cell density cultivations
Zinnecker, Tilia; Reichl, Udo; Genzel, Yvonne
In: Human vaccines & immunotherapeutics - Austin, Tex. : Landes Bioscience, Bd. 20 (2024), Heft 1, insges. 15 S.
Production of antiviral “OP7 chimera” defective interfering particles free of infectious virus
Pelz, Lars; Dogra, Tanya; Marichal-Gallardo, Pavel; Hein, Marc Dominique; Hemissi, Ghada; Kupke, Sascha Young; Genzel, Yvonne; Reichl, Udo
In: Applied microbiology and biotechnology - Berlin : Springer, Bd. 108 (2024), Artikel 97, insges. 15 S.
Tracing active members in microbial communities by BONCAT and click chemistry-based enrichment of newly synthesised proteins
Hellwig, Patrick; Kautzner, Daniel; Heyer, Robert; Dittrich, Anna; Wibberg, Daniel; Busche, Tobias; Winkler, Anika; Reichl, Udo; Benndorf, Dirk
In: ISME communications - Oxford : Oxford University Press, Bd. 4 (2024), Heft 1, Artikel ycae153, insges. 14 S., 1 Online-Ressource (14 Seiten)
Dissertation
In-depth characterization and cell culture-based production in influenza A virus defective interfering particles
Pelz, Lars; Reichl, Udo
In: Magdeburg: Universitätsbibliothek, Dissertation Otto-von-Guericke-Universität Magdeburg, Fakultät für Verfahrens- und Systemtechnik 2024, 1 Online-Ressource (Verschiedene Seitenzählungen, 13.32 MB) [Literaturangaben][Literaturangaben]
Anderes Material
Improved biological methanation using tubular foam-bed reactor
Khesali Aghtaei, Hoda; Hyer, Robert; Reichl, Udo; Benndorf, Dirk
In: Biotechnology for biofuels and bioproducts - London : BioMed Central , 2022, Bd. 17 (2024), Artikel 66, insges. 12 S.
2023
Begutachteter Zeitschriftenartikel
Process intensification strategies toward cell culture-based high-yield production of a fusogenic oncolytic virus
Göbel, Sven; Jaén, Karim E.; Dorn, Marie; Neumeyer, Victoria; Jordan, Ingo; Sandig, Volker; Reichl, Udo; Altomonte, Jennifer; Genzel, Yvonne
In: Biotechnology & bioengineering - New York, NY [u.a.] : Wiley, Bd. 120 (2023), Heft 9, S. 2639-2657
Reliable N-glycan analysis - removal of frequently occurring oligosaccharide impurities by enzymatic degradation
Burock, Robert; Cajic, Samanta; Henning, René; Buettner, Falk, F. R.; Reichl, Udo; Rapp, Erdmann
In: Molecules - Basel : MDPI, Bd. 28 (2023), Heft 4, Artikel 1843, insges. 19 S.
Cell-free biosynthesis meets dynamic optimization and control - a fed-batch framework
Espinel-Ríos, Sebastián; Huber, Nicolas; Alcalá-Orozco, Edgar Alberto; Morabito, Bruno; Rexer, Thomas F. T.; Reichl, Udo; Klamt, Steffen; Findeisen, Rolf
In: IFAC-PapersOnLine / Internationale Förderung für Automatische Lenkung - Frankfurt : Elsevier, Bd. 55 (2022), Heft 23, S. 92-97
Production of retroviral vectors in continuous high cell density culture
Hein, Marc D.; Kazenmaier, Daniel; van Heuvel, Yasemin; Dogra, Tanya; Cattaneo, Maurizio; Kupke, Sascha Y.; Stitz, Jörn; Genzel, Yvonne; Reichl, Udo
In: Applied microbiology and biotechnology - Berlin : Springer, Bd. 107 (2023), S. 5947-5961
Broad-spectrum antiviral activity of influenza A Defective Interfering Particles against respiratory syncytial, yellow fever, and Zika virus replication in vitro
Pelz, Lars; Piagnani, Elena; Marsall, Patrick; Wynserski, Nancy; Hein, Marc Dominique; Marichal-Gallardo, Pavel; Kupke, Sascha Young; Reichl, Udo
In: Viruses - Basel : MDPI, Bd. 15 (2023), Heft 9, Artikel 1872, insges. 17 S.
Characterization of a quail suspension cell line for production of a fusogenic oncolytic virus
Göbel, Sven; Jaén, Karim E.; Fernandes, Rita P.; Reiter, Manfred; Altomonte, Jennifer; Reichl, Udo; Genzel, Yvonne
In: Biotechnology & bioengineering - New York, NY [u.a.] : Wiley, Bd. 120 (2023), Heft 11, S. 3335-3346
A cell-free multi-enzyme cascade reaction for the synthesis of CDP-glycerol
Alcalá-Orozco, E. Alberto; Grote, Valerian; Fiebig, Timm; Klamt, Steffen; Reichl, Udo; Rexer, Thomas
In: ChemBioChem - Weinheim : Wiley-VCH, Bd. 24 (2023), Heft 21, Artikel e202300463
Cell-free N-glycosylation of peptides using synthetic lipid-linked hybrid and complex N-glycans
Wenzel, Lisa; Hoffmann, Marcus; Rapp, Erdmann; Rexer, Thomas F. T.; Reichl, Udo
In: Frontiers in molecular biosciences - Lausanne : Frontiers, Bd. 10 (2023), insges. 11 S.
Removable Ddes - the missing link for in-depth N-glycan analysis via multi-method approaches
Cajic, Samanta; Hennig, René; Grote, Valerian; Reichl, Udo; Rapp, Erdmann
In: Engineering - Beijing : Engineering Sciences Press., Bd. 26 (2023), S. 132-150
Generation of "OP7 chimera" defective interfering influenza A particle preparations free of infectious virus that show antiviral efficacy in mice
Dogra, Tanya; Pelz, Lars; Boehme, Julia D.; Kuechler, Jan; Kershaw, Olivia; Marichal-Gallardo, Pável Alejandro; Baelkner, Maike; Hein, Marc Dominique; Gruber, Achim; Benndorf, Dirk; Genzel, Yvonne; Bruder, Dunja; Kupke, Sascha Young; Reichl, Udo
In: Scientific reports - [London] : Macmillan Publishers Limited, part of Springer Nature, Bd. 13 (2023), Artikel 20936, insges. 13 S.
Buchbeitrag
Upstream processing for viral vaccines - general aspects
Pelz, Lars; Göbel, Sven; Jaen, Karim; Reichl, Udo; Genzel, Yvonne
In: Bioprocessing of viral vaccines , First edition - Abgingdon : Taylor & Francis ; Kamen, Amine . - 2023, S. 79-135
Upstream processing for viral vaccines - process intensification
Göbel, Sven; Pelz, Lars; Reichl, Udo; Genzel, Yvonne
In: Bioprocessing of viral vaccines , First edition - Abgingdon : Taylor & Francis ; Kamen, Amine . - 2023, S. 137-173
Aufsatz
Degradation kinetics of lignocellulolytic enzymes in a biogas reactor using quantitative mass spectrometry
Küchler, Jan; Willenbücher, Katharina; Reiß, Elisabeth; Nuß, Lea; Conrady, Marius; Ramm, Patrice; Schimpf, Ulrike; Reichl, Udo; Szewzyk, Ulrich; Benndorf, Dirk
In: Fermentation - Basel : MDPI, Bd. 9 (2023), Heft 1, Artikel 67, 1 Online-Ressource (12 Seiten)
Abstrakt
Adjuvanted SARS-CoV-2 spike protein vaccination with altered glycosylation elicits improved TH1 humoral and cellular immunity in mice
Rudert, J.; Bälkner, M.; Juarez-Osorio, M.; Rexer, T.; Reichl, Udo; Jacobsen, H.; Metzdorf, K.; Bruder, D.; Volckmar, J.
In: European journal of immunology - Weinheim : Wiley-VCH, Bd. 53 (2023), Heft S2, S. 358, Artikel P376 [Konferenz: Joint Conference of the Société Française d'Immunologie (SFI) and the Deutsche Gesellschaft für Immunologie (DGfI), Strasbourg, France, 26-29 September 2023]
2022
Begutachteter Zeitschriftenartikel
High-titer hepatitis C virus production in a scalable single-use high cell density bioreactor
Offersgaard, Anna; Duarte Hernandez, Carlos Rene; Pihl, Anne Finne; Venkatesan, Nadini Prabhakar; Krarup, Henrik; Lin, Xiangliang; Reichl, Udo; Bukh, Jens; Genzel, Yvonnne; Gottwein, Judith Margarete
In: Vaccines - Basel : MDPI, Bd. 10 (2022), Heft 2, Artikel 249, insges. 24 S.
Impact of influenza A virus infection on growth and metabolism of suspension MDCK cells using a dynamic model
Ramos, João Rodrigues Correia; Bissinger, Thomas; Genzel, Yvonne; Reichl, Udo
In: Metabolites - Basel : MDPI, Bd. 12 (2022), Heft 3, Artikel 239, insges. 27 S.
Cell-line screening and process development for a fusogenic oncolytic virus in small-scale suspension cultures
Göbel, Sven; Kortum, Fabian; Chavez, Karim Jaén; Jordan, Ingo; Sandig, Volker; Reichl, Udo; Altomonte, Jennifer; Genzel, Yvonne
In: Applied microbiology and biotechnology - Berlin : Springer, Bd. 106 (2022), Heft 13/16, S. 4945-4961
Human 3D airway tissue models for real-time microscopy - visualizing respiratory virus spreading
Möckel, Marion; Baldok, Nino; Walles, Thorsten; Hartig, Roland; Müller, Andreas Johann; Reichl, Udo; Genzel, Yvonne; Walles, Heike; Wiese-Rischke, Cornelia
In: Cells - Basel : MDPI, Bd. 11 (2022), Heft 22, Artikel 3634, insges. 21 S.
Dissertation
Mathematical models of influenza A virus infection - multiplicity of infection and its impact on co-infection and virus production
Rüdiger, Daniel; Tsotsas, Evangelos; Reichl, Udo
In: Magdeburg: Universitätsbibliothek, 2022, 1 Online-Ressource (XVIII, 179 Seiten, 8,16 MB), Illustrationen
Development of chromatography-based purification processes for cell culture-derived influenza virus particles
Weigel, Thomas; Reichl, Udo
In: Magdeburg: Universitätsbibliothek, Dissertation Otto-von-Guericke-Universität Magdeburg, Fakultät für Verfahrens- und Systemtechnik 2022, 1 Online-Ressource (XXII, 145 Seiten, 2,22 MB) [Literaturverzeichnis: Seite 119-133]
Cell culture-based production of influenza A virus-derived defective interfering particles
Hein, Marc Dominique; Reichl, Udo
In: Magdeburg: Universitätsbibliothek, Dissertation Otto-von-Guericke-Universität Magdeburg, Fakultät für Verfahrens- und Systemtechnik 2022, 1 Online-Ressource (XV, 98, XVII-L Seiten, 5,1 MB) [Literaturverzeichnis: Seite XX-XXXVII]
Buchbeitrag
Discovering biomarkers for non-alcoholic steatohepatitis patients with and without hepatocellular carcinoma using fecal metaproteomics
Sydor, Svenja; Dandyk, Christian; Schwerdt, Johannes; Manka, Paul; Benndorf, Dirk; Lehmann, Theresa; Schallert, Kay; Wolf, Maximilian; Reichl, Udo; Canbay, Ali E.; Bechmann, Lars P.; Heyer, Robert
In: International journal of molecular sciences - Basel : Molecular Diversity Preservation International, Bd. 23 (2022), Heft 16, Artikel 8841, insges. 14 S.
Aufsatz
Absolute quantification of viral proteins during single-round replication of MDCK suspension cells
Küchler, Jan; Püttker, Sebastian; Lahmann, Patrick; Genzel, Yvonne; Kupke, Sascha; Benndorf, Dirk; Reichl, Udo
In: Journal of proteomics - New York, NY [u.a.] : Elsevier, Bd. 259 (2022), Artikel 104544, insges. 10 S.
Adaptation of a microbial community to demand-oriented biological methanation
Khesali Aghtaei, Hoda; Püttker, Sebastian; Maus, Irena; Heyer, Robert; Huang, Liren; Sczyrba, Alexander; Reichl, Udo; Benndorf, Dirk
In: Biotechnology for biofuels and bioproducts - London : BioMed Central, Bd. 15 (2022), Heft 1, Artikel 125, 1 Online-Ressource (19 Seiten)
2021
Begutachteter Zeitschriftenartikel
Forschungsarbeiten am Institut für Verfahrenstechnik der OttovonGuerickeUniversität Magdeburg
Reichl, Udo; Seidel-Morgenstern, Andreas; Sundmacher, Kai; Tsotsas, Evangelos; Wachem, Berend
In: Chemie - Ingenieur - Technik - Weinheim : Wiley-VCH Verl., Bd. 93 (2021), Heft 3, S. 345-352
Multienzyme cascades for the in vitro synthesis of guanosine diphosphate Lfucose
Mahour, Reza; Marichal-Gallardo, Pavel A.; Rexer, Thomas; Reichl, Udo
In: ChemCatChem - Weinheim: WILEY-VCH Verlag, Bd. 13 (2021), insges. 11 S.
High cell density perfusion process for high yield of influenza A virus production using MDCK suspension cells
Wu, Yixiao; Bissinger, Thomas; Genzel, Yvonne; Liu, Xuping; Reichl, Udo; Tan, Wen-Song
In: Applied microbiology and biotechnology - Berlin: Springer, Bd. 105 (2021), 4, S. 1421-1434
Comprehensive N‐glycosylation analysis of the influenza A virus proteins HA and NA from adherent and suspension MDCK cells
Pralow, Alexander; Hoffmann, Marcus; Nguyen-Khuong, Terry; Pioch, Markus; Hennig, René; Genzel, Yvonne; Rapp, Erdmann; Reichl, Udo
In: The FEBS journal / Vereinigung der Europäischen Biochemischen Gesellschaften - Oxford [u.a.] : Wiley-Blackwell, Bd. 288 (2021), Heft 16, S. 4869-4891
Site-specific N-glycosylation analysis of animal cell culture-derived Zika virus proteins
Pralow, Alexander; Nikolay, Alexander; Leon, Arnaud; Genzel, Yvonne; Rapp, Erdmann; Reichl, Udo
In: Scientific reports - [London] : Macmillan Publishers Limited, part of Springer Nature, Bd. 11 (2021), Artikel 5147
Single-use capture purification of adeno-associated viral gene transfer vectors by membrane-based steric exclusion chromatography
Marichal-Gallardo, Pavel; Börner, Kathleen; Pieler, Michael M.; Sonntag-Buck, Vera; Obr, Martin; Bejarano, David; Wolff, Michael W.; Kräusslich, Hans-Georg; Reichl, Udo; Grimm, Dirk
In: Human gene therapy - New York, NY : Liebert, Bd. 32 (2021), Heft 17/18, S. 959-974
Cell culture-based production and in vivo characterization of purely clonal defective interfering influenza virus particles
Hein, Marc D.; Arora, Prerna; Marichal-Gallardo, Pável Alejandro; Winkler, Michael; Genzel, Yvonne; Pöhlmann, Stefan; Schughart, Klaus; Kupke, Sascha Y.; Reichl, Udo
In: BMC biology - Berlin: Springer, Bd. 19 (2021)
SARS-CoV-2 production in a scalable high cell density bioreactor
Offersgaard, Anna; Duarte Hernandez, Carlos Rene; Pihl, Anne Finne; Costa, Rui; Venkatesan, Nandine Prabhakar; Lin, Xiangliang; Pham, Long Van; Feng, Shan; Fahnøe, Ulrik; Scheel, Troels Kasper Høyer; Ramirez, Santseharay; Reichl, Udo; Bukh, Jens; Genzel, Yvonne; Gottwein, Judith Margarete
In: Vaccines - Basel: MDPI, Bd. 9 (2021), 7
Antiviral activity of influenza A virus defective interfering particles against SARS-CoV-2 replication in vitro through stimulation of innate immunity
Rand, Ulfert; Kupke, Sascha Young; Shkarlet, Hanna; Hein, Marc Dominique; Hirsch, Tatjana; Marichal-Gallardo, Pável Alejandro; Cicin-Sain, Luka; Reichl, Udo; Bruder, Dunja
In: Cells - Basel: MDPI, 2012, Bd. 10 (2021), 7, insges. 14 S.
Towards integrated production of an influenza A vaccine candidate with MDCK suspension cells
Bissinger, Thomas; Wu, Yixiao; Marichal-Gallardo, Pável Alejandro; Riedel, Dietmar; Liu, Xuping; Genzel, Yvonne; Tan, Wen-Song; Reichl, Udo
In: Biotechnology & bioengineering - New York, NY [u.a.]: Wiley, Bd. 118 (2021), 10, S. 3996-4013
Integrated cycles for urban biomass as a strategy to promote a CO2-neutral society - a feasibility study
Meinusch, Nicole; Kramer, Susanne; Körner, Oliver; Wiese, Jürgen; Seick, Ingolf; Beblek, Anita; Berges, Regine; Illenberger, Bernhard; Illenberger, Marco; Uebbing, Jennifer; Wolf, Maximilian; Saake, Gunter; Benndorf, Dirk; Reichl, Udo; Heyer, Robert
In: Sustainability - Basel : MDPI, Bd. 13 (2021), Heft 17, Artikel 9505, insges. 22 S.
Combining functional metagenomics and glycoanalytics to identify enzymes that facilitate structural characterization of sulfated N-glycans
Chuzel, Léa; Fossa, Samantha L.; Boisvert, Madison L.; Cajic, Samanta; Heenig, René; Ganatra, Mehul B.; Reichl, Udo; Rapp, Erdmann; Taron, Christopher H.
In: Microbial cell factories - London : Biomed Central, Bd. 20 (2021), S. 1-17, Artikel 162
Multiscale model of defective interfering particle replication for influenza A virus infection in animal cell culture
Rüdiger, Daniel; Pelz, Lars; Hein, Marc D.; Kupke, Sascha Y.; Reichl, Udo
In: PLoS Computational Biology/ Public Library of Science - San Francisco, Calif.: Public Library of Science, Bd. 17 (2021), 9, insges. 28 S.
Cell culture-based production of defective interfering influenza A virus particles in perfusion mode using an alternating tangential flow filtration system
Hein, Marc D.; Chawla, Anshika; Cattaneo, Maurizio; Kupke, Sascha Y.; Genzel, Yvonne; Reichl, Udo
In: Applied microbiology and biotechnology - Berlin : Springer, Bd. 105 (2021), S. 7251–7264
A high cell density perfusion process for Modified Vaccinia virus Ankara production - process integration with inline DNA digestion and cost analysis
Gränicher, Gwendal; Babakhani, Masoud; Göbel, Sven; Jordan, Ingo; Marichal-Gallardo, Pavel; Genzel, Yvonne; Reichl, Udo
In: Biotechnology & bioengineering - New York, NY [u.a.] : Wiley, Bd. 118 (2021), Heft 12, S. 4720-4734
Cell-free glycoengineering of the recombinant SARS-CoV-2 spike glycoprotein
Ruhnau, Johannes; Grote, Valerian; Juarez-Osorio, Mariana; Bruder, Dunja; Mahour, Reza; Rapp, Erdmann; Rexer, Thomas F. T.; Reichl, Udo
In: Frontiers in Bioengineering and Biotechnology - Lausanne: Frontiers Media, 2013, Bd. 9 (2021), insges. 10 S.
Continuous purification of influenza A virus particles using pseudo-affinity membrane chromatography
Fortuna, Raquel A.; Taft, Florian; Villain, Louis; Wolff, Michael W.; Reichl, Udo
In: Journal of biotechnology - Amsterdam [u.a.]: Elsevier Science, Bd. 342 (2021), S. 139-148
Cell-free multi-enzyme synthesis and purification of uridine diphosphate galactose
Mahour, Reza; Lee, Ju Weon; Grimpe, Pia; Boecker, Simon; Grote, Valerian; Klamt, Steffen; Seidel-Morgenstern, Andreas; Rexer, Thomas F. T.; Reichl, Udo
In: ChemBioChem - Weinheim : Wiley-VCH, Bd. 23 (2022), Heft 2, Artikel e202100361, insges. 11 S.
Semi-continuous propagation of influenza A virus and its defective interfering particles - analyzing the dynamic competition to select candidates for antiviral therapy
Pelz, Lars; Rüdiger, Daniel; Dogra, Tanya; Alnaji, Fadi G.; Genzel, Yvonne; Brooke, Christopher B.; Kupke, Sascha Y.; Reichl, Udo
In: Journal of virology - Baltimore, Md.: Soc., Bd. 95 (2021), 24, insges. 18 S.
Dissertation
Metaproteomanalyse methanogener Mikrobiome aus Anreicherungskulturen im Labormaßstab
Kohrs, Fabian; Reichl, Udo
In: Magdeburg: Universitätsbibliothek, 2021, 1 Online-Ressource (IX, 123, A-J Seiten, 3,84 MB), Illustrationen
Mathematical models of influenza A virus infection - elucidating the impact of host cell factors and defective interfering particles on virus growth
Laske, Tanja; Sundmacher, Kai; Reichl, Udo
In: Magdeburg: Universitätsbibliothek, 2021, 1 Online-Ressource (XVIII, 233 Seiten, 17,07 MB), Illustrationen, Diagramme
Process intensification for the production of MVA and influenza A virus in high density suspension cultures of AGE1.CR.pIX cells
Vázquez Ramírez, Daniel; Reichl, Udo
In: Magdeburg: Universitätsbibliothek, 2021, 1 Online-Ressource (XIV, 136 Seiten, 7,58 MB), Illustrationen
Process intensification and integration for the production of vaccines and viral vectors
Gränicher, Gwendal; Reichl, Udo
In: Magdeburg: Universitätsbibliothek, 2021, 1 Online-Ressource (XXX, 222 Seiten, 8,49 MB), Illustrationen, Diagramme
Application of functional metagenomics to the field of glycobiology
Chuzel, Léa; Reichl, Udo
In: Düren: Shaker Verlag, 2022, Dissertation Otto-von-Guericke-Universität Magdeburg, Fakultät für Verfahrens- und Systemtechnik 2021, XI, 229 Seiten - (Forschungsberichte aus dem Max-Planck-Institut für Dynamik komplexer technischer Systeme; Band 55), ISBN: 3-8440-8437-1 [Literaturverzeichnis: Seite 186-210]
Scalable multi-enzyme platforms for the in vitro glycoengineering of therapeutic proteins & synthesis of human milk oligosaccharides
Mahour, Reza; Reichl, Udo
In: Magdeburg: Universitätsbibliothek, 2022, 1 Online-Ressource (XV, 170 Blätter, 5,8 MB), Illustrationen
Buchbeitrag
Correction to: Animal Cell Expression Systems
Butler, M.; Reichl, Udo
In: Advances in Glycobiotechnology - Cham: Springer International Publishing; Rapp, Erdmann . - 2021, S. 459-461
Preface
Rapp, Erdmann; Reichl, Udo
In: Advances in Glycobiotechnology - Cham: Springer International Publishing; Rapp, Erdmann . - 2021, S. v-vi
Aufsatz
OP7, a novel influenza A virus defective interfering particle - production, purification, and animal experiments demonstrating antiviral potential
Hein, Marc D.; Kollmus, Heike; Marichal-Gallardo, Pavel; Püttker, Sebastian; Benndorf, Dirk; Genzel, Yvonne; Schughart, Klaus; Kupke, Sascha Y.; Reichl, Udo
In: Applied microbiology and biotechnology - Berlin : Springer, Bd. 105 (2021), Heft 1, S. 129-146
Tracking changes in adaptation to suspension growth for MDCK cells: cell growth correlates with levels of metabolites, enzymes and proteins
Pech, Sabine; Rehberg, Markus; Janke, Robert; Benndorf, Dirk; Genzel, Yvonne; Muth, Thilo; Sickmann, Albert; Rapp, Erdmann; Reichl, Udo
In: Applied microbiology and biotechnology - Berlin : Springer, Bd. 105 (2021), S. 1861-1874
Fecal metaproteomics reveals reduced gut inflammation and changed microbial metabolism following lifestyle-induced weight loss
Biemann, Ronald; Buß, Enrico; Benndorf, Dirk; Lehmann, Theresa; Schallert, Kay; Püttker, Sebastian; Reichl, Udo; Isermann, Berend; Schneider, Jochen; Saake, Gunter; Heyer, Robert
In: Biomolecules - Basel : MDPI - Vol.11.2021, 5, 726, insgesamt 13 Seiten
MPA_Pathway_Tool - user-friendly, automatic assignment of microbial community data on metabolic pathways
Walke, Daniel; Schallert, Kay; Ramesh, Prasanna; Benndorf, Dirk; Lange, Emanuel; Reichl, Udo; Heyer, Robert
In: International journal of molecular sciences - Basel : Molecular Diversity Preservation International, Bd. 22 (2021), Heft 20, Artikel 10992, insges. 12 S.
Critical Assessment of MetaProteome Investigation (CAMPI) - a multi-laboratory comparison of established workflows
Van Den Bossche, Tim; Kunath, Benoit J.; Schallert, Kay; Schäpe, Stephanie S.; Abraham, Paul C.; Armengaud, Jean; Arntzen, Magnus Ø.; Bassignani, Ariane; Benndorf, Dirk; Fuchs, Steohan; Giannone, Richard J.; Griffin, Timothy J.; Hagen, Live H.; Halder, Rashi; Henry, Céline; Hettich, Robert L.; Heyer, Robert; Jagtap, Pratik; Jehmlich, Nico; Jensen, Marlene; Juste, Ctherine; Kleiner, Manuel; Langella, Olivier; Lehmann, Theresa; Leith, Emma; May, Patrick; Mesuere, Bart; Miotello, Guylaine; Peters, Samantha L.; Pible, Olivier; Queiros, Pedro T.; Reichl, Udo; Renard, Bernhard Y.; Schiebenhoefer, Henning; Sczyrba, Alexander; Tanca, Alessandro; Trappe, Kathrin; Trezzi, jean-Pierre; Uzzau, Sergio; Verschaffelt, Pieter; Bergen, Martin von; Wilmes, Paul; Wolf, Maximilian; Martens, Lennart; Muth, Thilo
In: Nature Communications - [London] : Nature Publishing Group UK, Bd. 12 (2021), S. 1-15, Artikel 7305
Herausgeberschaft
Advances in glycobiotechnology
Rapp, Erdmann; Reichl, Udo
In: Cham: Springer, 2021, viii, 461 Seiten - (Advances in biochemical engineering/biotechnology; 175), ISBN: 978-3-030-69589-7 [Literaturangaben]
2020
Begutachteter Zeitschriftenartikel
Single-cell analysis uncovers a vast diversity in intracellular viral defective interfering RNA content affecting the large cell-to-cell heterogeneity in influenza A virus replication
Kupke, Sascha Young; Ly, Lam-Ha; Börno, Stefan Thomas; Ruff, Alexander; Timmermann, Bernd; Vingron, Martin; Haas, Stefan; Reichl, Udo
In: Viruses - Basel: MDPI, 12 (2020,1), Artikelnummer 71, 19 Seiten
A dynamic model linking cell growth to intracellular metabolism and extracellular by‐product accumulation
Ramos, João R.; Rath, Alexander G.; Genzel, Yvonne; Sandig, Volker; Reichl, Udo
In: Biotechnology & bioengineering - New York, NY [u.a.] : Wiley, Bd. 117 (2020), Heft 5, S. 1533-1553
Performance of an acoustic settler versus a hollow fiberbased ATF technology for influenza virus production in perfusion
Gränicher, Gwendal; Coronel, Juliana; Trampler, Felix; Jordan, Ingo; Genzel, Yvonne; Reichl, Udo
In: Applied microbiology and biotechnology - Berlin: Springer, Bd. 104.2020, S. 4877-4888
Virus harvesting in perfusion culture - choosing the right type of hollow fiber membrane
Nikolay, Alexander; Grooth, de Joris; Genzel, Yvonne; Wood, Jeffery A.; Reichl, Udo
In: Biotechnology & bioengineering - New York, NY [u.a.] : Wiley, Bd. 117 (2020), Heft 10, S. 3040-3052
Application of an nnclined settler for cell culture-based influenza A virus production in perfusion mode
Coronel, Juliana; Gränicher, Gwendal; Sandig, Volker; Noll, Thomas; Genzel, Yvonne; Reichl, Udo
In: Frontiers in Bioengineering and Biotechnology - Lausanne: Frontiers Media, Volume 8 (2020), article 672, insgesmat 13 Seiten
Production of Modified Vaccinia Ankara virus by intensified cell cultures - a comparison of platform technologies for viral vector production
Gränicher, Gwendal; Tapia, Felipe; Behrendt, Ilona; Jordan, Ingo; Genzel, Yvonne; Reichl, Udo
In: Biotechnology journal - Weinheim: Wiley-VCH, Bd. 16 (2021), 1, insges. 10 S., 2020
Dissertation
Single-cell analysis of influenza A virus replication - sources of cell-to-cell heterogeneity and discoverey of a novel type of defective interfering particle
Kupke, Sascha Young; Reichl, Udo
In: Magdeburg, Dissertation Otto-von-Guericke-Universität Magdeburg, Fakultät für Verfahrens- und Systemtechnik 2020, XV, 155 Seiten [Literaturverzeichnis: Seite 122-136][Literaturverzeichnis: Seite 122-136]
Intensified yellow fever and Zika virus production in animal cell culture
Nikolay, Alexander; Reichl, Udo
In: Magdeburg, Dissertation Otto-von-Guericke-Universität Magdeburg, Fakultät für Verfahrens- und Systemtechnik 2020, XV, 175 Seiten [Literaturverzeichnis: Seite 139-157][Literaturverzeichnis: Seite 139-157]
In-depth mass spectrometry-based glycoproteomics - advances in sample preparation, measurement and data-analysis of glycoproteins
Hoffmann, Marcus; Reichl, Udo; Rapp, Erdmann
In: Magdeburg, Dissertation Otto-von-Guericke-Universität Magdeburg, Fakultät für Verfahrens- und Systemtechnik 2020, XI, 141 Seiten [Literaturverzeichnis: Seite 118-133][Literaturverzeichnis: Seite 118-133]
Evaluation of MDCK suspension cell lines for influenza A virus production - media, metabolism, and process conditions
Bissinger, Thomas; Reichl, Udo
In: Magdeburg, Dissertation Otto-von-Guericke-Universität Magdeburg, Fakultät für Verfahrens- und Systemtechnik 2020, XXVI, 137 Seiten [Literaturverzeichnis: Seite 109-125][Literaturverzeichnis: Seite 109-125]
Buchbeitrag
Impact of feeding and stirring regimes on the internal stratification of microbial communities in the fermenter of anaerobic digestion plants
Heyer, Robert; Klang, Johanna; Hellwig, Patrick; Schallert, Kay; Kress, Philipp; Hülsemann, Benedikt; Theuerl, Susanne; Reichl, Udo; Benndorf, Dirk
In: Bioresource technology - Amsterdam [u.a.] : Elsevier Science - 314(2020), Artikel-Nummer 123679, 1 Online-Ressource
Perfusion control for high cell density cultivation and viral vaccine production
Nikolay, Alexander; Bissinger, Thomas; Gränicher, Gwendal; Wu, Yixiao; Genzel, Yvonne; Reichl, Udo
In: Animal Cell Biotechnology: Methods and Protocols - New York, NY: Springer US; Pörtner, Ralf . - 2020, S. 141-168
Artikel in Zeitschrift
Synthesis of lipid-linked oligosaccharides by a compartmentalized multi-enzyme cascade for the in vitro N-glycosylation of peptides
Rexer, Thomas F. T.; Wenzel, Lisa; Hoffmann, Marcus; Tischlik, Sebastian; Bergmann, Christin; Grote, Valerian; Boecker, Simon Matthias; Bettenbrock, Katja; Schildbach, Anna; Kottler, Robert; Mahour, Reza; Rapp, Erdmann; Pietzsch, Markus; Reichl, Udo
In: Journal of biotechnology - Amsterdam [u.a.]: Elsevier Science, 1984, Bd. 322 (2020), S. 54-65
2019
Begutachteter Zeitschriftenartikel
A novel type of influenza a virus-derived defective interfering particle with nucleotide substitutions in its genome
Kupke, Sascha Young; Riedel, Dietmar; Frensing, Timo; Zmora, Pawel; Reichl, Udo
In: Journal of virology: publ. by the American Society for Microbiology - Baltimore, Md.: Soc., 1967, Bd. 93.2019, 4, Art.-Nr. e01786, insges. 24 Seiten
High-throughput serum N-glycomics - method comparison and application to study rheumatoid arthritis and pregnancy-associated changes
Reiding, Karli R.; Bondt, Albert; Hennig, René; Gardner, Richard A.; O'Flaherty, Roisin; Trbojevič-Akmačič, Irena; Shubhakar, Archana; Hazes, Johanna M. W.; Reichl, Udo; Fernandes, Daryl L.; Pučič-Bakovič, Maja; Rapp, Erdmann; Spencer, Daniel I. R.; Dolhain, Radboud J. E. M.; Rudd, Pauline M.; Lauc, Gordon; Wuhrer, Manfred
In: Molecular & cellular proteomics: MCP - Bethesda, Md: The American Society for Biochemistry and Molecular Biology, Bd. 18.2019, 1, S. 3-15
Enzymatic cascade synthesis provides novel linear human milk oligosaccharides as reference standards for xCGELIF based highthroughput analysis
Fischöder, Thomas; Cajic, Samanta; Reichl, Udo; Rapp, Erdmann; Elling, Lothar
In: Biotechnology journal - Weinheim: Wiley-VCH, Vol. 14 (2019), 3, Artikelnr. 1800305, insges. 9 Seiten
A system for production of defective interfering particles in the absence of infectious influenza A virus
Bdeir, Najat; Arora, Prerna; Gärtner, Sabine; Hoffmann, Markus; Reichl, Udo; Pöhlmann, Stefan; Winkler, Michael
In: PLOS ONE - San Francisco, California, US: PLOS, Vol. 14.2019, 3, Artikel e0212757, insgesamt 18 Seiten
High titer MVA and influenza A virus production using a hybrid fed-batch/perfusion strategy with an ATF system
Vázquez Ramírez, Daniel; Jordan, Ingo; Sandig, Volker; Genzel, Yvonne; Reichl, Udo
In: Applied microbiology and biotechnology - Berlin: Springer, Bd. 103 (2019), 7, S. 3025-3035
Hydrophobic-interaction chromatography for purification of influenza A and B virus
Weigel, Thomas; Soliman, Remon; Wolff, Michael W.; Reichl, Udo
In: Journal of chromatography / B - New York, NY [u.a.]: Science Direct, Bd. 1117.2019, S. 103-117
Use of sulfated cellulose membrane adsorbers for chromatographic purification of cell cultured-derived influenza A and B viruses
Fortuna, A. Raquel; van Teeffelen, Sebastian; Ley, Adrian; Fischer, Laura M.; Taft, Florian; Genzel, Yvonne; Villain, Louis; Wolff, Michael W.; Reichl, Udo
In: Separation and purification technology - Amsterdam [u.a.]: Elsevier Science, 1997, Bd. 226.2019, S. 350-358
A robust and universal metaproteomics workflow for research studies and routine diagnostics within 24 h using phenol extraction, FASP digest, and the MetaProteomeAnalyzer
Heyer, Robert; Schallert, Kay; Büdel, Anja; Zoun, Roman; Dorl, Sebastian; Behne, Alexander; Kohrs, Fabian; Püttker, Sebastian; Siewert, Corina; Muth, Thilo; Saake, Gunter; Reichl, Udo; Benndorf, Dirk
In: Frontiers in microbiology - Lausanne : Frontiers Media - 10 (2019), article 1883, insgesamt 20 Seiten
Influenza A virus production in a single-use orbital shaken bioreactor with ATF or TFF perfusion systems
Coronel, Juliana; Behrendt, Ilona; Bürgin, Tim; Anderlei, Tibor; Sandig, Volker; Reichl, Udo; Genzel, Yvonne
In: Vaccine - Amsterdam: Elsevier, Bd. 37.2019, 47, S. 7011-7018
Efficient influenza A virus production in high cell density using the novel porcine suspension cell line PBG.PK2.1
Gränicher, Gwendal; Coronel, Juliana; Pralow, Alexander; Marichal-Gallardo, Pável Alejandro; Wolff, Michael; Rapp, Erdmann; Karlas, Alexander; Sandig, Volker; Genzel, Yvonne; Reichl, Udo
In: Vaccine - Amsterdam: Elsevier, 1983, Bd. 37.2019, 47, S. 7019-7028
Enzymatic cascades for tailored 13 C 6 and 15 N enriched human milk oligosaccharides
Fischöder, Thomas; Cajic, Samanta; Grote, Valerian; Greifenstein, Raphael; Reichl, Udo; Franzreb, Matthias; Rapp, Erdmann; Elling, Lothar
In: Molecules - Basel : MDPI - Volume 24 (2019), 19, Artikel 3482, insgesamt 21 Seiten
Semi-perfusion cultures of suspension MDCK cells enable high cell concentrations and efficient influenza A virus productionPK2.1
Bissinger, Thomas; Fritsch, Johannes; Mihut, Adrian; Wu, Yxiao; Liu, Xuping; Genzel, Yvonne; Tan, Wen-Song; Reichl, Udo
In: Vaccine - Amsterdam: Elsevier, Bd. 37 (2019), 47, S. 7003-7010
Production of Defective Interfering Particles of influenza A virus in parallel continuous cultures at two residence times - insights from qPCR measurements and viral dynamics modeling
Tapia Delgado, Felipe Ignacio; Laske, Tanja; Wasik, Milena A.; Rammhold, Markus; Genzel, Yvonne; Reichl, Udo
In: Frontiers in Bioengineering and Biotechnology - Lausanne: Frontiers Media, 2013, Volume 7 (2019), Artikel 275, insgesamt 15 Seiten
Continuous influenza virus production in a tubular bioreactor system provides stable titers and avoids the von Magnus effect
Tapia Delgado, Felipe Ignacio; Wohlfahrth, Daniel; Sandig, Volker; Jordan, Ingo; Genzel, Yvonne; Reichl, Udo
In: PLOS ONE - San Francisco, California, US: PLOS, 2006, 14 (2019), 11, article e0224317, insgesamt 21 Seiten
Dissertation
Charakterisierung der Influenzavirus-Vermehrung in genetisch veränderten humanen Zelllinien zur Optimierung der Impfstoffproduktion
Bachmann, Mandy; Reichl, Udo
In: Magdeburg, Dissertation Otto-von-Guericke-Universität Magdeburg, Fakultät für Verfahrens- und Systemtechnik 2019, XI, 173 Seiten [Literaturverzeichnis: Seite 133-155][Literaturverzeichnis: Seite 133-155]
Herstellungsprozess für onkolytische Masernviren
Grein, Tanja A.; Reichl, Udo
In: Düren: Shaker Verlag, 2019, XII, 195 Seiten, 24 Illustrationen, Diagramme, 21 cm, 314 g - (Schriftenreihe des Institutes für Bioverfahrenstechnik und Pharmazeutische Technologie; Band 15)
Chromatographic purification of biological macromolecules by their capture on hydrophilic surfaces with the aid of non-ionic polymers
Marichal-Gallardo, Pável Alejandro; Reichl, Udo
In: Magdeburg, Dissertation Otto-von-Guericke-Universität Magdeburg, Fakultät für Verfahrens- und Systemtechnik 2019, xiii, 118 Blätter [Literaturverzeichnis: Blatt 99-113][Literaturverzeichnis: Blatt 99-113]
Continuous upstream processing for cell culture-derived virus production
Tapia Delgado, Felipe Ignacio; Reichl, Udo
In: Magdeburg, Dissertation Otto-von-Guericke-Universität Magdeburg, Fakultät für Verfahrens- und Systemtechnik 2019, xv, 112 Blätter [Literaturverzeichnis: Blatt 92-106][Literaturverzeichnis: Blatt 92-106]
Buchbeitrag
Metaproteomics of fecal samples of Crohn's disease and Ulcerative Colitis
Lehmann, Tony; Schallert, Kay; Vilchez-Vargas, Ramiro; Benndorf, Dirk; Püttker, Sebastian; Sydor, Svenja; Schulz, Christian; Bechmann, Lars Peter; Canbay, Ali E.; Heidrich, Benjamin; Reichl, Udo; Link, Alexander; Heyer, Robert
In: Journal of proteomics - New York, NY [u.a.] : Elsevier, Bd. 201 (2019), S. 93-103
Aufsatz
RedCom - a strategy for reduced metabolic modeling of complex microbial communities and its application for analyzing experimental datasets from anaerobic digestion
Koch, Sabine; Kohrs, Fabian; Lahmann, Patrick; Bissinger, Thomas; Wendschuh, Stefan; Benndorf, Dirk; Reichl, Udo
In: PLoS Computational Biology / Public Library of Science - San Francisco, Calif. : Public Library of Science - Vol. 15 (2019), 2, Artikel e1006759, insgesamt 32 Seiten
Metaproteome analysis reveals that syntrophy, competition, and phage-host interaction shape microbial communities in biogas plants
Heyer, Robert; Schallert, Kay; Siewert, C.; Kohrs, F.; Greve, J.; Maus, I.; Klang, J.; Klocke, M.; Heiermann, M.; Hoffmann, Michael; Püttker, Sebastian; Calusinska, M.; Zoun, Roman; Saake, Gunter; Benndorf, Dirk; Reichl, Udo
In: Microbiome - London : Biomed Central, Bd. 7 (2019), Artikel 69, insges. 17 S.
Abstrakt
Dialyseinduzierte Veränderungen im menschlichen Serum-Protein N-Glykosylation
Lindquist, Jonathan; Hennig, René; Rapp, Erdmann; Reichl, Udo; Mertens, Peter Rene
In: Kongress für Nephrologie, 11. Jahrestagung der Deutschen Gesellschaft für Nephrologie: Die Nephrologie als ganzheitliche Disziplin in der Patientenversorgung : 10. 13. Oktober 2019 in Düsseldorf : Programm/ Kongress für Nephrologie, 2019, P256, S. 165
2018
Begutachteter Zeitschriftenartikel
Cell culture-based production of defective interfering particles for influenza antiviral therapy
Wasik, Milena A.; Eichwald, Luca; Genzel, Yvonne; Reichl, Udo
In: Applied microbiology and biotechnology - Berlin: Springer, 1975, Bd. 102.2018, 3, S. 1167-1177, 2017
MPA portable - a stand-alone software package for analyzing metaproteome samples on the go
Muth, Thilo; Kohrs, Fabian; Heyer, Robert; Benndorf, Dirk; Rapp, Erdmann; Reichl, Udo; Martens, Lennart; Renard, Bernhard Y.
In: Analytical chemistry - Columbus, Ohio : American Chemical Society , 1947, Bd. 90 (2018), Heft 1, S. 685-689
Optimization of cell culture-derived influenza A virus particles purification using sulfated cellulose membrane adsorbers
Fortuna, Ana Raquel; Taft, Florian; Villain, Louis; Wolff, Michael W.; Reichl, Udo
In: Engineering in life sciences - Weinheim: Wiley-VCH, Bd. 18.2018, 1, S. 29-39
High-cell-density cultivations to increase MVA virus production
Vázquez Ramírez, Daniel; Genzel, Yvonne; Jordan, Ingo; Sandig, Volker; Reichl, Udo
In: Vaccine - Amsterdam : Elsevier, Bd. 36 (2018), Heft 22, S. 3124-3133
Purification of cell culture-derived influenza A virus via continuous anion exchange chromatography on monoliths
Fischer, Laura M.; Wolff, Michael; Reichl, Udo
In: Vaccine - Amsterdam: Elsevier, Bd. 36.2018, 22, S. 3153-3160
Valorisation of deinking sludge as a substrate for lignocellulolytic enzymes production by Pleurotus ostreatus
Vodovnik, Maša; Vrabec, Katja; Hellwig, Patrick; Benndorf, Dirk; Sežun, Mija; Gregori, Andrej; Gottumukkala, Lalitha D.; Anderson, Robin C.; Reichl, Udo
In: Journal of cleaner production - Amsterdam [u.a.] : Elsevier Science - Vol. 197.2018, Part 1, S. 253-263
SDSPAGE fractionation to increase metaproteomic insight into the taxonomic and functional composition of microbial communities for biogas plant samples
Wenzel, Lisa; Heyer, Robert; Schallert, Kay; Löser, Lucy; Wünschiers, Röbbe; Reichl, Udo; Benndorf, Dirk
In: Engineering in life sciences - Weinheim : Wiley-VCH, Bd. 18 (2018), Heft 7, S. 498-509
Establishment of a five-enzyme cell-free cascade for the synthesis of uridine diphosphate N-acetylglucosamine
Mahour, Reza; Klapproth, Jan; Rexer, Thomas F. T.; Schildbach, Anna; Klamt, Steffen; Pietzsch, Markus; Rapp, Erdmann; Reichl, Udo
In: Journal of biotechnology - Amsterdam [u.a.]: Elsevier Science, Bd. 283.2018, S. 120-129
Process intensification of EB66® cell cultivations leads to high-yield yellow fever and Zika virus production
Nikolay, Alexander; Léon, Arnaud; Schwamborn, Klaus; Genzel, Yvonne; Reichl, Udo
In: Applied microbiology and biotechnology - Berlin: Springer, 1975, Bd. 102.2018, 20, S. 8725-8737
Purification of influenza viruslike particles using sulfated cellulose membrane adsorbers
Carvalho, Sofia B.; Fortuna, A. Raquel; Wolff, Michael W.; Peixoto, Cristina; Alves, Paula M.; Reichl, Udo
In: Journal of chemical technology & biotechnology - Chichester: Wiley, Bd. 93.2018, 7, S. 1988-1996[Special issue: Bioseparations]
Propagation of Brazilian Zika virus strains in static and suspension cultures using Vero and BHK cells
Nikolay, Alexander; Castilho, Leda R.; Reichl, Udo; Genzel, Yvonne
In: Vaccine - Amsterdam: Elsevier, 1983, Bd. 36.2018, 22, S. 3140-3145
A multiscale model of influenza A virus replication covering highly different infection conditions in cell cultures
Rüdiger, D.; Kupke, S. Y.; Reichl, Udo
In: IFAC-PapersOnLine/ Internationale Förderung für Automatische Lenkung - Frankfurt: Elsevier, Bd. 51.2018, 19, S. 32-33[Konferenz: 7th Conference on Foundation of Systems Biology in Engineering, FOSBE 2018, Chicago, Illinois, USA, 05-08 August 2018]
glyXtoolMS - an open-source pipeline for semiautomated analysis of glycopeptide mass spectrometry data
Pioch, Markus; Hoffmann, Marcus; Prahlow, Alexander; Reichl, Udo; Rapp, Erdmann
In: Analytical chemistry: the authoritative voice of the analytical community - Columbus, Ohio: American Chemical Society, 1947, Bd. 90.2018, 20, S. 11908-11916
Improvement of electrospray stability in negative ion mode for nano-PGC-LC-MS glycoanalysis via post-column make-up flow
Nguyen-Khuong, Terry; Pralow, Alexander; Reichl, Udo; Rapp, Erdmann
In: Glycoconjugate journal: official journal of the International Glycoconjugate Organization - Dordrecht [u.a.]: Springer Science + Business Media B.V, Bd. 35.2018, 6, S. 499-509
The fine art of destruction - a guide to indepth glycoproteomic analyses-exploiting the diagnostic potential of fragment ions
Hoffmann, Marcus; Pioch, Markus; Pralow, Alexander; Henning, René; Kottler, Robert; Reichl, Udo; Rapp, Erdmann
In: Proteomics - Weinheim: Wiley VCH, 2001, Vol. 18.2018, 24, Art.-Nr. 1800282
Buchbeitrag
Mathematical modeling as a tool to improve influenza vaccine production processes
Duvigneau, Stefanie; Dürr, Robert; Laske, Tanja; Bachmann, Mandy; Dostert, Melanie; Reichl, Udo; Kienle, Achim
In: IFAC-PapersOnLine / Internationale Förderung für Automatische Lenkung - Frankfurt : Elsevier, Bd. 51 (2018), Heft 19, S. 1-4
Aufsatz
One pot synthesis of GDP-mannose by a multi-enzyme cascade for enzymatic assembly of lipid-linked oligosaccharides
Rexer, Thomas F. T.; Schildbach, Anna; Klapproth, Jan; Schierhorn, Angelika; Mahour, Reza; Pietzsch, Markus; Rapp, Erdmann; Reichl, Udo
In: Biotechnology & bioengineering - New York, NY [u.a.] : Wiley, Bd. 115 (2018), Heft 1, S. 192-205
2017
Begutachteter Zeitschriftenartikel
Steric exclusion chromatography for purification of cell culture-derived influenza A virus using regenerated cellulose membranes and polyethylene glycol
Marichal-Gallardo, Pável Alejandro; Pieler, Michael M.; Wolff, Michael W.; Reichl, Udo
In: Journal of chromatography - New York, NY [u.a.] : Science Direct, Bd. 1483.2017, S. 110-119
Efficient and stable production of Modified Vaccinia Ankara virus in two-stage semi-continuous and in continuous stirred tank cultivation systems
Tapia Delgado, Felipe Ignacio; Jordan, Ingo; Genzel, Yvonne; Reichl, Udo
In: PLOS ONE - San Francisco, California, US : PLOS - Bd. 12.2017, 8, Art.-Nr. e0182553, insges. 17 Seiten
Improvement of the glycoproteomic toolbox with the discovery of a unique C-terminal cleavage specificity of flavastacin for N-glycosylated asparagine
Pralow, Alexander; Hoffmann, Marcus; Nguyen-Khuong, Terry; Rapp, Erdmann; Reichl, Udo
In: Scientific reports - [London] : Macmillan Publishers Limited, part of Springer Nature - Bd. 7.2017, Art.-Nr. 11419, insgesamt 9 Seiten
Influence of the production system on the surface properties of influenza A virus particles
Hämmerlein, Frank; Pieler, Michael M.; Hennig, René; Serve, Anja; Rapp, Erdmann; Wolff, Michael W.; Reichl, Udo; Hubbuch, Jürgen
In: Engineering in life sciences - Weinheim : Wiley-VCH, Bd. 17.2017, 10, S. 1071-1077
Specific ion effects on the particle size distributions of cell culturederived influenza A virus particles within the Hofmeister series
Pieler, Michael Martin; Heyse, Anja; Wolff, Michael Werner; Reichl, Udo
In: Engineering in life sciences - Weinheim : Wiley-VCH, Bd. 17.2017, 5, S. 470-478
Dissertation
Investigation of influenza virus particle aggregation and purification with magnetic sulfated cellulose particles
Pieler, Michael Martin; Reichl, Udo
In: Magdeburg, 2017, xxv, 97 Seiten, Illustrationen
Charakterisierung von mikrobiellen Gemeinschaften aus Biogasanlagen mittels Metaproteomanalyse und Korrelationen der Ergebnisse zu den Prozessparametern
Heyer, Robert Steven; Reichl, Udo
In: Magdeburg, Dissertation Otto-von-Guericke-Universität Magdeburg, Fakultät für Verfahrens- und Systemtechnik 2017, XVII, 164, xxxvii Blätter, Illustrationen
Characterisation of cell growth, metabolism and recombinant protein production during transient and steady state conditions for the human cell line AGE1.HN.AAT
Rath, Alexander Georg; Sundmacher, Kai; Reichl, Udo
In: Magdeburg, Dissertation Otto-von-Guericke-Universität Magdeburg, Fakultät für Verfahrens- und Systemtechnik 2017, XV, 178, xvi Seiten [Literaturverzeichnis: Seite 147-168]
Buchbeitrag
Proteotyping of laboratory-scale biogas plants reveals multiple steady-states in community composition
Kohrs, Fabian; Heyer, Robert; Bissinger, Thomas; Kottler, Robert; Schallert, Kay; Püttker, Sebastian; Behne, Alexander; Rapp, Erdmann; Benndorf, Dirk; Reichl, Udo
In: Anaerobe - London : Academic Press, Bd. 46 (2017), S. 56-68
Animal cell expression systems
Butler, M.; Reichl, Udo
In: Advances in biochemical engineering, biotechnology - Berlin : Springer . - 2017, S. 1-36
2016
Begutachteter Zeitschriftenartikel
A membrane-based purification process for cell culture-derived influenza A virus
Weigel, Thomas; Solomaier, Thomas; Wehmeyer, Sebastian; Peuker, Alessa; Wolff, Michael W.; Reichl, Udo
In: Journal of biotechnology - Amsterdam [u.a.]: Elsevier Science, 1984, Bd. 220.2016, S. 12-20
Sialic acid-specific affinity chromatography for the separation of erythropoietin glycoforms using serotonin as a ligand
Meininger, M.; Stepath, M.; Hennig, R.; Cajic, S.; Rapp, E.; Rotering, H.; Wolff, M. W.; Reichl, Udo
In: Journal of chromatography / B - New York, NY [u.a.]: Science Direct, 1977, Bd. 1012/1013.2016, S. 193-203
Site-specific O-glycosylation analysis of human blood plasma proteins
Hoffmann, Marcus; Marx, Kristina; Reichl, Udo; Wuhrer, Manfred; Rapp, Erdmann
In: Molecular & cellular proteomics: MCP - Bethesda, Md: The American Society for Biochemistry and Molecular Biology, 2002, Bd. 15.2016, 2, S. 624-641
Impaired antiviral response of adenovirus-transformed cell lines supports virus replication
Bachmann, Mandy; Breitwieser, Theresa; Lipps, Christoph; Wirth, Dagmar; Jordan, Ingo; Reichl, Udo; Frensing, Timo
In: Journal of general virology: JGV - Reading: Soc., 1967, Bd. 97.2016, 2, S. 293-298
Glycomic characterization of induced pluripotent stem cells derived from a patient suffering from phosphomannomutase 2 congenital Disorder of glycosylation (PMM2-CDG)
Thiesler, Christina T.; Cajic, Samanta; Hoffmann, Dirk; Thiel, Christian; Diepen, Laura van; Hennig, René; Sgodda, Malte; Weiβmann, Robert; Reichl, Udo; Steinemann, Doris; Diekmann, Ulf; Huber, Nicolas M. B.; Oberbeck, Astrid; Cantz, Tobias; Kuss, Andreas W.; Körner, Christian; Schambach, Axel; Rapp, Erdmann; Büttner, Falk
In: Molecular & cellular proteomics - Bethesda, Md. : The American Society for Biochemistry and Molecular Biology, Bd. 15 (2016), Heft 4, S. 1435-1452
Diagnostic concept for dynamically operated biogas production plants
Bensmann, Astrid; Hanke-Rauschenbach, Richard; Heyer, Robert; Kohrs, Fabian; Benndorf, Dirk; Kausmann, Robert; Plöchl, Matthias; Heiermann, Monika; Reichl, Udo; Sundmacher, Kai
In: Renewable energy - Amsterdam [u.a.]: Elsevier Science, Vol. 96.2016, Part A, S. 479-489
Reprint of "Modeling the intracellular replication of influenza A virus in the presence of defective interfering RNAs
Laske, Tanja; Heldt, Frank Stefan; Hoffmann, Helene; Frensing, Timo; Reichl, Udo
In: Virus research : an international journal of molecular and cellular virology. - Amsterdam [u.a.] : Elsevier Science, Bd. 218.2016, S. 86-95
Early changes in the metabolic profile of activated CD8+ T cells
Cammann, Clemens; Rath, Alexander; Reichl, Udo; Lingel, Holger; Brunner-Weinzierl, Monika; Simeoni, Luca; Schraven, Burkhart; Lindquist, Jonathan A.
In: BMC cell biology - London : BioMed Central - Bd. 17.2016, Art.-Nr. 28, insges. 11 S.
Towards personalized diagnostics via longitudinal study of the human plasma N-glycome
Hennig, René; Cajic, Samanta; Borowiak, Matthias; Hoffmann, Marcus; Kottler, Robert; Reichl, Udo; Rapp, Erdmann
In: Biochimica et biophysica acta / General subjects: BBA - Amsterdam [u.a.]: Elsevier, 1964, Bd. 1860.2016, 8, S. 1728-1738
Influenza virus intracellular replication dynamics, release kinetics, and particle morphology during propagation in MDCK cells
Frensing, Timo; Kupke, Sascha Young; Bachmann, Mandy; Fritzsche, Susanne; Gallo-Ramirez, Lili E.; Reichl, Udo
In: Applied microbiology and biotechnology - Berlin: Springer, 1975, Bd. 100.2016, 16, S. 7181-7192
Ezrin and HNRNP expression correlate with increased virus release rate and early onset of virus-induced apoptosis of MDCK suspension cells
Kluge, Sabine; Genzel, Yvonne; Laus, Kim; Serve, Anja; Pflugmacher, Antje; Peschel, Britta; Rapp, Erdmann; Reichl, Udo
In: Biotechnology journal : BTJ ; systems & synthetic biology, nanobiotech, medicine. - Weinheim : Wiley-VCH, Bd. 11.2016, 10, S. 1332-1342
A cell culture-derived whole virus influenza A vaccine based on magnetic sulfated cellulose particles confers protection in mice against lethal influenza A virus infection
Pieler, Michael M.; Frentzel, Sarah; Bruder, Dunja; Wolff, Michael W.; Reichl, Udo
In: Vaccine - Amsterdam: Elsevier, 1983, Bd. 34.2016, 50, S. 6367-6374
Binding kinetics and multi-bond : finding correlations by synthesizing interactions between ligand-coated bionanoparticles and receptor surfaces
Wang, Wenjing; Voigt, Andreas; Wolff, Michael W.; Reichl, Udo; Sundmacher, Kai
In: Analytical biochemistry : methods in the biological sciences. - San Diego, Calif : Elsevier, Bd. 505.2016, S. 8-17
Bioreactors for high cell density and continuous multi-stage cultivations: options for process intensification in cell culture-based viral vaccine production
Tapia Delgado, Felipe Ignacio; Vázquez Ramírez, Daniel; Genzel, Yvonne; Reichl, Udo
In: Applied microbiology and biotechnology - Berlin: Springer, Bd. 100 (2016), 5, S. 2121-2132
Metaproteomics applied to activated sludge for industrial wastewater treatment revealed a dominant methylotrophic metabolism of Hyphomicrobium zavarzinii
Salerno, Carlo; Benndorf, Dirk; Pech, Sabine; Palese, Luigi Leonardo; Reichl, Udo; Pollice, Alfieri
In: Microbial ecology - New York, NY: Springer . - 2016
Dissertation
Proteomanalytik der Adaption tierischer Zelllinien an Suspensionswachstum und optimierte Medien im Kontext der Impfstoffproduktion
Pech, Sabine; Reichl, Udo
In: Magdeburg: Otto-von-Guericke-Universität Magdeburg, 2016, XXIV, 192, lxxvii Seiten, Illustrationen, Diagramme, 30 cm
Purification of cell culture-derived influenza virus using simulated moving bed chromatography
Kröber, Tina; Reichl, Udo; Seidel-Morgenstern, Andreas
In: Magdeburg, 2016, XX, 171 Seiten, Illustrationen, Diagramme, 30 cm
Modellbasierte Bestimmung von Interventionsstrategien zur Optimierung der Produktion von Biokraftstoffen in Cyanobakterien
Erdrich, Philipp; Reichl, Udo; Kienle, Achim
In: Magdeburg, Dissertation Otto-von-Guericke-Universität Magdeburg, Fakultät für Verfahrens- und Systemtechnik 2016, xx, 158 Seiten [Literaturverzeichnis: Seite 131-158][Literaturverzeichnis: Seite 131-158]
Novel computational methods for the analysis and interpretation of MS/MS data in metaproteomics
Muth, Thilo; Weiß, Helmut; Reichl, Udo
In: Magdeburg, 2016, XVI, 197 Seiten, Illustrationen
Etablierung und Anwendung einer durchflusszytometrischen Methode für die Vitalitätsbestimmung von P. aeruginosa, B. cepacia und S. aureus in Mischkulturen
Rüger, Marc; Reichl, Udo
In: Magdeburg, 2016, XIV, 161, viii Blätter, Illustrationen
Aufsatz
Proteotyping of biogas plant microbiomes separates biogas plants according to process temperature and reactor type
Heyer, Robert; Benndorf, Dirk; Kohrs, F.; Vrieze, J.; Boon, N.; Hoffmann, M.; Rapp, Erdmann; Schlüter, A.; Sczyrba, A.; Reichl, Udo
In: Biotechnology for biofuels - London : BioMed Central, Bd. 9 (2016), Heft 1
Predicting compositions of microbial communities from stoichiometric models with applications for the biogas process
Koch, Sabine; Benndorf, Dirk; Fronk, Karen; Reichl, Udo; Klamt, Steffen
In: Biotechnology for biofuels - London : BioMed Central, Bd. 9 (2016), Heft 17, insges. 16 S.
2015
Begutachteter Zeitschriftenartikel
Bioreactor concepts for cell culture-based viral vaccine production
Gallo-Ramírez, Lilí Esmeralda; Nikolay, Alexander; Genzel, Yvonne; Reichl, Udo
In: Expert review of vaccines - Abingdon, Oxon: Taylor & Francis, 2002, Bd. 14.2015, 9, S. 1181-1195
Navigating through metaproteomics data - a logbook of database searching
Muth, Thilo; Kolmeder, Carolin A.; Salojärvi, Jarkko; Keskitalo, Salla; Varjosalo, Markku; Verdam, Froukje J.; Rensen, Sander S.; Reichl, Udo; Vos, Willem M.; Rapp, Erdmann; Martens, Lennart
In: Proteomics - Weinheim: Wiley VCH, 2001, Bd. 15.2015, 20, S. 3439-3453
Colonic metaproteomic signatures of active bacteria and the host in obesity
Kolmeder, Carolin A.; Ritari, Jarmo; Verdam, Froukje J.; Muth, Thilo; Keskitalo, Salla; Varjosalo, Markku; Fuentes, Susana; Greve, Jan Willem; Buurman, Wim A.; Reichl, Udo; Rapp, Erdmann; Martens, Lennart; Palva, Airi; Salonen, Anne; Rensen, Sander S.; Vos, Willem M.
In: Proteomics - Weinheim : Wiley VCH, Bd. 15 (2015), Heft 20, S. 3544-3552
Modeling the intracellular replication of influenza A virus in the presence of defective interfering RNAs
Laske, Tanja; Heldt, Frank Stefan; Hoffmann, Helene; Frensing, Timo; Reichl, Udo
In: Virus research: an international journal of molecular and cellular virology - Amsterdam [u.a.]: Elsevier Science, 1984, Bd. 213.2015, S. 90-99
Editorial: Can modern vaccine technology pursue the success of traditional vaccine manufacturing?
Grabherr, Reingard; Reichl, Udo
In: Biotechnology journal: BTJ : systems & synthetic biology, nanobiotech, medicine - Weinheim: Wiley-VCH, Bd. 10.2015, 5, S. 657-658
Monitoring changes in proteome during stepwise adaptation of a MDCK cell line from adherence to growth in suspension
Pech, Sabine; Benndorf, Dirk; Genzel, Yvonne; Scharfenberg, Klaus; Rapp, Erdmann; Reichl, Udo
In: Vaccine - Amsterdam: Elsevier, Bd. 33 (2015), 35, S. 4269-4280
Exclusive decoration of simian immunodeficiency virus Env with high-mannose type N-glycans is not compatible with mucosal transmission in rhesus macaques
Karsten, Christina B.; Büttner, Falk; Cajic, Samanta; Nehlmeier, Inga; Neumann, Berit; Klippert, Antonina; Sauermann, Ulrike; Reichl, Udo; Gerardy-Schahn, Rita; Rapp, Erdmann; Stahl-Hennig, Christiane; Pöhlmann, Stefan
In: Journal of virology - Baltimore, Md. : Soc., Bd. 89 (2015), Heft 22, S. 11727-11733
Community shifts in a well-operating agricultural biogas plant - how process variations are handled by the microbiome
Theuerl, Susanne; Kohrs, Fabian; Benndorf, Dirk; Maus, Irena; Wibberg, Daniel; Schlüter, Andres; Kausmann, Robert; Heiermann, Monika; Rapp, Erdmann; Reichl, Udo; Pühler, Alfred; Klocke, Michael
In: Applied microbiology and biotechnology - Berlin: Springer, Bd. 99 (2015), 18, S. 7791-7803
Single-cell analysis and stochastic modelling unveil large cell-to-cell variability in influenza A virus infection
Heldt, Frank S.; Kupke, Sascha Young; Dorl, Sebastian; Reichl, Udo; Frensing, Timo
In: Nature Communications - [London]: Nature Publishing Group UK, 2010, Vol. 6.2015, Art. 8938, insgesamt 12 S.
Dissertation
Mathematical models of influenza A virus infection - from intracellular replication to virus growth in cell populations
Heldt, Frank Stefan; Frensing, Timo; Reichl, Udo
In: Magdeburg, Univ., Fak. für Verfahrens- und Systemtechnik, Diss., 2015, 2014, XX, 190 S., graph. Darst.
Infection dynamics and virus-induced apoptosis in influenza virus A infected adherent and suspension MDCK cells
Peschel, Britta; Reichl, Udo; Marwan, Wolfgang
In: Aachen: Shaker, Zugl.: Magdeburg, Univ., Fak. für Verfahrens- und Systemtechnik, Diss., 2015, VI, 180 S. - (Forschungsberichte aus dem Max-Planck-Institut für Dynamik komplexer technischer Systeme; 44), ISBN: 978-3-8440-3738-8
Population balance modeling of influenza A virus replication in MDCK cells during vaccine production
Müller, Thomas; Kienle, Achim; Reichl, Udo
In: Magdeburg, Univ., Fak. für Elektrotechnik und Informationstechnik, Diss., 2015, X, 127 S.
Buchbeitrag
The MetaProteomeAnalyzer - a powerful open-source software suite for metaproteomics data analysis and interpretation
Muth, Thilo; Behne, Alexander; Heyer, Robert; Kohrs, Fabian; Benndorf, Dirk; Hoffmann, Marcus; Lehtevä, Miro; Reichl, Udo; Martens, Lennart; Rapp, Erdmann
In: Journal of proteome research - Washington, DC : ACS Publications, Bd. 14 (2015), Heft 3, S. 1557-1565
Comparison of influenza virus particle purification using magnetic sulfated cellulose particles with an established centrifugation method for analytics
Serve, Anja; Pieler, Michael Martin; Benndorf, Dirk; Rapp, Erdmann; Wolff, Michael Werner; Reichl, Udo
In: Analytical chemistry - Columbus, Ohio : American Chemical Society, Bd. 87 (2015), Heft 21, S. 10708-10711
Aufsatz
Fractionation of biogas plant sludge material improves metaproteomic characterization to investigate metabolic activity of microbial communities
Kohrs, Fabian; Wolter, Sophie; Benndorf, Dirk; Heyer, Robert; Hoffmann, Marcus; Rapp, Erdmann; Bremges, Andreas; Sczyrba, Alexander; Schlüter, Andreas; Reichl, Udo
In: Proteomics - Weinheim : Wiley VCH, Bd. 15 (2015), Heft 20, S. 3585-3589
Metaproteomics of activated sludge from a wastewater treatment plant - a pilot study
Püttker, Sebastian; Kohrs, Fabian; Benndorf, Dirk; Heyer, Robert; Rapp, Erdmann; Reichl, Udo
In: Proteomics - Weinheim : Wiley VCH, Bd. 15 (2015), Heft 20, S. 3596-3601
Metaproteomics of complex microbial communities in biogas plants
Heyer, Robert; Kohrs, Fabian; Reichl, Udo; Benndorf, Dirk
In: Microbial biotechnology - Oxford : Wiley-Blackwell, Bd. 8 (2015), Heft 5, S. 749-763
2014
Begutachteter Zeitschriftenartikel
Avidity of influenza virus: Model-based identification of adsorption kinetics from surface plasmon resonance experiments
Wang, Wenjing; Wolff, Michael W.; Reichl, Udo; Sundmacher, Kai
In: Journal of chromatography / A - New York, NY [u.a.]: Science Direct, Bd. 1326.2014, S. 125-129
The influence of cell growth and enzyme activity changes on intracellular metabolite dynamics in AGE1.HN.AAT cells
Rath, Alexander; Rehberg, Markus; Janke, Robert; Genzel, Yvonne; Scholz, Sebastian; Noll, Thomas; Rose, Thomas; Sandig, Volker; Reichl, Udo
In: Journal of biotechnology - Amsterdam [u.a.]: Elsevier Science, Bd. 178.2014, S. 43-53
Impact of defective interfering particles on virus replication and antiviral host response in cell culture-based influenza vaccine production
Frensing, Timo; Pflugmacher, Antje; Bachmann, Mandy; Peschel, Britta; Reichl, Udo
In: Applied microbiology and biotechnology - Berlin: Springer, 1975, Bd. 98.2014, 21, S. 8999-9008
The avian cell line AGE1.CR.pIX characterized by metabolic flux analysis
Lohr, Verena; Hädicke, Oliver; Genzel, Yvonne; Jordan, Ingo; Büntemeyer, Heino; Klamt, Steffen; Reichl, Udo
In: BMC biotechnology - London: BioMed Central, Vol. 14.2014, Art. 72 insgesamt 14 S.
Glycolysis is governed by growth regime and simple enzyme regulation in adherent MDCK cells
Rehberg, Markus; Ritter, Joachim B.; Reichl, Udo
In: PLoS Computational Biology: a new community journal - San Francisco, Calif: Public Library of Science, Vol. 10.2014, 10, Art. e1003885, insgesamt 16 S.
Production of high-titer human influenza A virus with adherent and suspension MDCK cells cultured in a single-use hollow fiber bioreactor
Tapia Delgado, Felipe Ignacio; Vogel, Thomas; Genzel, Yvonne; Behrendt, Ilona; Hirschel, Mark; Gangemi, J. David; Reichl, Udo
In: Vaccine - Amsterdam: Elsevier, 1983, Bd. 32.2014, 8, S. 1003-1011
Comparative performance of four methods for high-throughput glycosylation analysis of immunoglobulin G in genetic and epidemiological
Huffman, Jennifer E.; Pučić-Baković, Maja; Klarić, Lucija; Hennig, René; Selman, Maurice H. J.; Vučković, Frano; Novokmet, Mislav; Krištić, Jasminka; Borowiak, Matthias; Muth, Thilo; Polašek, Ozren; Razdorov, Genadij; Gornik, Olga; Plomp, Rosina; Theodoratou, Evropi; Wright, Alan F.; Rudan, Igor; Hayward, Caroline; Campbell, Harry; Deelder, André M.; Reichl, Udo; Aulchenko, Yurii S.; Rapp, Erdmann; Wuhrer, Manfred; Lauc, Gordan
In: Molecular & cellular proteomics: MCP - Bethesda, Md: The American Society for Biochemistry and Molecular Biology, Bd. 13.2014, S. 1598-1610
A flow-through chromatography process for influenza A and B virus purification
Weigel, Thomas; Solomaier, Thomas; Peuker, Alessa; Pathapati, Trinath; Wolff, Michael W.; Reichl, Udo
In: Journal of virological methods - Amsterdam [u.a.]: Elsevier Science, Bd. 207.2014, S. 45-53
High cell density cultivations by alternating tangential flow (ATF) perfusion for influenza A virus production using suspension cells
Genzel, Yvonne; Vogel, Thomas; Buck, Johannes; Behrendt, Ilona; Vázquez Ramírez, Daniel; Schiedner, Gudrun; Jordan, Ingo; Reichl, Udo
In: Vaccine - Amsterdam: Elsevier, Bd. 32 (2014), 24, S. 2770-2781
Biological methanation of hydrogen within biogas plants - a model-based feasibility study
Bensmann, Astrid; Hanke-Rauschenbach, R.; Heyer, Robert; Kohrs, Fabian; Benndorf, Dirk; Reichl, Udo; Sundmacher, Kai
In: Applied energy - Amsterdam [u.a.]: Elsevier Science, Bd. 134 (2014), S. 413-425
Changes in intracellular metabolite pools during growth of adherent MDCK cells in two different media
Rehberg, M.; Rath, A.; Ritter, J. B.; Genzel, Y.; Reichl, Udo
In: Applied microbiology and biotechnology - Berlin: Springer, Bd. 98.2014, 1, S. 385-397
Habilitation
Improving industrial antibody manufacturing processes using animal cell culture technology
Pohlscheidt, Michael; Reichl, Udo
In: Magdeburg, Univ., Fak. für Verfahrens- und Systemtechnik, Habil.-Schr., 2014, Getr. Zählung, Ill., graph. Darst., 30 cm
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