Prof. Bertrand

Prof. Dr. rer. nat. Jessica Bertrand

Medizinische Fakultät/Universitätsklinikum A.ö.R. (FME/UKMD)
Orthopädische Universitätsklinik (KORT)
Haus 28, Leipziger Str. 44, 39120, Magdeburg,
Projekte
Publikationen

2019

Abstrakt

Held, Annelena;  Bollmann, Miriam;  Hansen, Uwe;  Pap, Thomas;  Dell'Accio, Francesco;  Prein, Carina;  Aszodi, Attila;  Clausen-Schaumann, Hauke;  Bertrand, Jessica 

Inhibition of SDC4-LOX mediated extracellular matrix stiffening prevents chondrocyte differentiation in OA cartilage via increased YAP/TAZ signaling
In: Osteoarthritis and cartilage - [S.l.]: Elsevier, Bd. 27.2019, Suppl. 1, S. S150-S151

Bollmann, Miriam;  Pap, Thomas;  Lohmann, Christoph H.;  Bertrand, Jessica 

Matrix metalloproteinase mediated shedding of Syndecan-4 under osteoarthritis conditions
In: Osteoarthritis and cartilage - [S.l.]: Elsevier, Bd. 27.2019, Suppl. 1, S. S196-S197

Begutachteter Zeitschriftenartikel

Döring, Joachim;  Crackau, Maria;  Nestler, Christian;  Welzel, Florian;  Bertrand, Jessica;  Lohmann, Christoph H. 

Characteristics of different cathodic arc deposition coatings on CoCrMo for biomedical applications
In: Journal of the mechanical behavior of biomedical materials - Amsterdam [u.a.]: Elsevier, Bd. 97.2019, S. 212-221

Chamaon, Kathrin;  Schönfeld, Peter;  Awiszus, Friedemann;  Bertrand, Jessica;  Lohmann, Christoph H. 

Ionic cobalt but not metal particles induces ROS generation in immune cells in vitro
In: Journal of biomedical materials research / B - Hoboken, NJ: Wiley, Bd. 107.2019, 4, S. 1246-1253

Harrach, Saliha;  Barz, Vivien;  Pap, Thomas;  Pavenstädt, Hermann;  Schlatter, Eberhard;  Edemir, Bayram;  Distler, Jörg Hans Wilhelm;  Ciarimboli, Giuliano;  Bertrand, Jessica 

Notch-signaling activity determines uptake and biological effect of imatinib in systemic sclerosis dermal fibroblasts
In: The journal of investigative dermatology - Amsterdam: Elsevier, Bd. 139.2019, 2, S. 439-447

Römmelt, Constantin;  Munsch, Thomas;  Drynda, Andreas;  Leßmann, Volkmar;  Lohmann, Christoph H.;  Bertrand, Jessica 

Periprosthetic hypoxia as consequence of TRPM7 mediated cobalt influx in osteoblasts
In: Journal of biomedical materials research / B - Hoboken, NJ: Wiley, Bd. 107.2019, 6, S. 1806-1813

Bertrand, Jessica;  Bollmann, Miriam 

Soluble syndecans - biomarkers for diseases and therapeutic options
In: British journal of pharmacology - Malden, MA: Wiley, Bd. 176.2019, 1, S. 67-81

Sanchez, Christelle;  Lambert, Cécile;  Dubuc, Jean-Emile;  Bertrand, Jessica;  Pap, Thomas;  Henrotin, Yves 

Syndecan-4 is increased in osteoarthritic knee, but not hip or shoulder, articular hypertrophic chondrocytes
In: Cartilage - London: Sage, Bd. 10.2019, insges. 10 S.

2018

Abstrakt

Bertrand, Jessica;  Kräft, Tabea;  Nitschke, Yvonne;  Rutsch, Frank;  Liote, Frederic;  Pap, Thomas 

BCP crystals drive chondrocyte hypertrophic differentiation via binding WNT ligands and activation of canonical WNT signaling
In: Osteoarthritis and cartilage - [S.l.]: Elsevier, Bd. 26.2018, Suppl. 1, S. S62-S63

Drynda, Susanne;  Drynda, Andreas;  Kekow, Jörn;  Lohmann, Christoph H.;  Bertrand, Jessica 

Influence of cobalt (II) + and chromium (III)-ions on bone formation in human osteoblast-like cells in-vitro
In: Annals of the rheumatic diseases - London: BMJ Publ. Group, Bd. 77.2018, Suppl. 2, AB0107, S. 1248-1249

Bollmann, Miriam;  Colombo, Federico;  Macor, Paolo;  De Maso, Luca;  Brandstädter, Knut;  Lohmann, Christoph H.;  Bertrand, Jessica 

Inhibition of the complement system component C5 as possible treatment in OA
In: Osteoarthritis and cartilage - [S.l.]: Elsevier, Bd. 26.2018, Suppl. 1, S. S108

Sühn, Thomas;  Döring, Joachim;  Bertrand, Jessica;  Lohmann, Christoph H.;  Shetty, Sagar;  Boese, Axel;  Friebe, Michael 

Initial results on energy harvesting by exploiting the temperature gradient in hip implants
In: Biomedical engineering - Berlin [u.a.]: de Gruyter, Vol. 63.2018, Suppl.1, Abstract P 065, S. S364

Stolberg-Stolberg, Josef;  Böttcher, Annika;  Sherwood, Joanna;  Sambale, Meike;  Raschke, Michael;  Pap, Thomas;  Bertrand, Jessica 

Programmed cell death and toll-like receptor activation in articular cartilage
In: Osteoarthritis and cartilage - [S.l.]: Elsevier, Bd. 26.2018, Suppl. 1, S. S70-S71

Sherwood, Joanna;  Sambale, Meike;  Bertrand, Jessica;  Dell'Accio, Francesco;  Pap, Thomas 

Transient receptor potential cation channel (TRPC6) as a regulator of CXCR2-mediated articular cartilage homeostasis
In: Osteoarthritis and cartilage - [S.l.]: Elsevier, Bd. 26.2018, Suppl. 1, S. S96-S97

Begutachteter Zeitschriftenartikel

Hawellek, Thelonius;  Hubert, Jan;  Hischke, Sandra;  Krause, Matthias;  Bertrand, Jessica;  Schmidt, Burkhard C.;  Kronz, Andreas;  Püschel, Klaus;  Rüther, Wolfgang;  Niemeier, Andreas 

Calcification of the acetabular labrum of the hip - prevalence in the general population and relation to hip articular cartilage and fibrocartilage degeneration
In: Arthritis Research & Therapy - London: BioMed Central, Bd. 20.2018, Art.-Nr. 104, insges. 10 S.

Bertrand, Jessica;  Delfosse, Daniel;  Mai, Viola;  Awiszus, Friedemann;  Harnisch, Karsten;  Lohmann, Christoph H. 

Ceramic prosthesis surfaces induce an inflammatory cell response and fibrotic tissue changes
In: Bone & joint journal - B & J journal: B & J journal - London: British Editorial Society of Bone and Joint Surgery, Bd. 100-B.2018, 7, Seite 882-890

Drynda, Andreas;  Drynda, Susanne;  Kekow, Jörn;  Lohmann, Christoph H.;  Bertrand, Jessica 

Differential effect of cobalt and chromium ions as well as CoCr particles on the expression of osteogenic markers and osteoblast function
In: International journal of molecular sciences - Basel: Molecular Diversity Preservation International, Bd. 19.2018, 10, Art.-Nr. 3034, insges. 16 S.

Held, Annelena;  Glas, Adrian;  Dietrich, Laura;  Bollmann, Miriam;  Brandstädter, Knut;  Großmann, Tom N.;  Lohmann, Christoph H.;  Pap, Thomas;  Bertrand, Jessica 

Targeting β-catenin dependent Wnt signaling via peptidomimetic inhibitors in murine chondrocytes and OA cartilage
In: Osteoarthritis and cartilage - [S.l.]: Elsevier, Bd. 26.2018, 6, S. 818-823

Drynda, Susanne;  Drynda, Andreas;  Feuerstein, Bernd;  Kekow, Jörn;  Lohmann, Christoph H.;  Bertrand, Jessica 

The effects of cobalt and chromium ions on transforming growth factor-beta patterns and mineralization in human osteoblast-like MG63 and SaOs-2 cells
In: Journal of biomedical materials research / A - New York, NY [u.a.]: Wiley, Bd. 106.2018, 8, S. 2105-2115

Meinshausen, Ann-Kathrin;  Märtens, Nicole;  Berth, Alexander;  Färber, Jacqueline;  Awiszus, Friedemann;  Macor, Paolo;  Lohmann, Christoph H.;  Bertrand, Jessica 

The terminal complement pathway is activated in septic but not in aseptic shoulder revision arthroplasties
In: Journal of shoulder and elbow surgery - St. Louis, Mo: Mosby, Bd. 27.2018, 10, S. 1837-1844

2017

Abstrakt

Bertrand, Jessica 

Calcium crystals and their link to osteoarthritis
In: Annals of the rheumatic diseases - London: BMJ Publ. Group, Bd. 76.2017, Suppl. 2, SP0057, S. 14

Böttcher, Annika;  Stolberg-Stolberg, Josef;  Raschke, Michael;  Pap, Thomas;  Bertrand, Jessica 

Nucleotide binding TLR dependent signalling cascades are activated upon cartilage trauma
In: Osteoarthritis and cartilage - [S.l.]: Elsevier, Bd. 25.2017, Suppl. 1, Abs. 264, S. S171

Bollmann, Miriam;  Gronau, Tobias;  Pap, Thomas;  Lohmann, Christoph H.;  Bertrand, Jessica 

Shed syndecan 4 in synovial fluid as a biomarker for OA severity
In: Osteoarthritis and cartilage - [S.l.]: Elsevier, Bd. 25.2017, Suppl. 1, Abs. 119, S. S93-S94

Held, Annelena;  Prein, Carina;  Aszodi, Attila;  Kronenberg, Daniel;  Hansen, Uwe;  Clausen-Schaumann, Hauke;  Pap, Thomas;  Bertrand, Jessica 

Syndecan-4 deficiency affects extracellular matrix architecture of articular cartilage
In: Osteoarthritis and cartilage - [S.l.]: Elsevier, Bd. 25.2017, Suppl. 1, Abs. 211, S. S146

Sherwood, Joanna;  Bertrand, Jessica;  Dell'Accio, Francesco;  Pap, Thomas 

The role of transient receptor potential cation channel trpc6 activity in cxcr2-mediated chondrocyte phenotypic stability
In: Osteoarthritis and cartilage - [S.l.]: Elsevier, Bd. 25.2017, Suppl. 1, Abs. 16, S. S19

Artikel in Zeitschrift

Harrach, Saliha;  Edemir, Bayram;  Schmidt-Lauber, Christian;  Pap, Thomas;  Bertrand, Jessica;  Ciarimboli, Giuliano 

Importance of the novel organic cation transporter 1 for tyrosine kinase inhibition by saracatinib in rheumatoid arthritis synovial fibroblasts
In: Scientific reports- [London]: Macmillan Publishers Limited, part of Springer Nature, 2011, Bd. 7.2017, S. 1258

Begutachteter Zeitschriftenartikel

Gronau, Tobias;  Krüger, Karsten;  Prein, Carina;  Aszodi, Attila;  Gronau, Isabel;  Iozzo, Renato V.;  Mooren, Frank C.;  Clausen-Schaumann, Hauke;  Bertrand, Jessica;  Pap, Thomas;  Bruckner, Peter;  Dreier, Rita 

Forced exercise-induced osteoarthritis is attenuated in mice lacking the small leucine-rich proteoglycan decorin
In: Annals of the rheumatic diseases - London: BMJ Publ. Group, Bd. 76.2017, 2, S. 442-449

Buchbeitrag

Bertrand, Jessica;  Held, Annelena 

Role of proteoglycans in osteoarthritis
In: Cartilage: Volume 2: Pathophysiology - Cham: Springer International Publishing, S. 63-80, 2017

2016

Abstrakt

Sherwood, Joanna;  Bertrand, Jessica;  Seidemann, M.;  Dell'Accio, Francesco;  Pap, Thomas 

Activation of the transient receptor potential cation channel TRPC6 is required for chondrocyte phenotypic stability
In: Osteoarthritis and cartilage. - [S.l.] : Elsevier; Bd. 24.2016, Suppl. 1, Abs. 249, S. S152-S153

Gronau, Tobias;  Krüger, Karsten;  Prein, Carina;  Hansen, Uwe;  Seidler, Daniela G.;  Iozzo, Renato V.;  Aszodi, Attila;  Clausen-Schaumann, Hauke;  Mooren, Frank C.;  Bertrand, Jessica;  Pap, Thomas;  Bruckner, Peter;  Dreier, Rita 

Altered matrix stiffness in decorin-null articular cartilage results in improved resistance to osteoarthritis induced by forced exercise
In: Osteoarthritis and cartilage. - [S.l.] : Elsevier; Bd. 24.2016, Suppl. 1, Abs. 214, S. S134

Nalesso, Giovanna;  Wagner, K.;  Bertrand, Jessica;  Sherwood, Joanna C.;  Thomas, B.L.;  Eldridge, Suzanne E.;  Pitzalis, Costantino;  Dell'Accio, Francesco 

Pharmacological blockade of CAMKII is detrimental for osteoarthritis progression
In: Osteoarthritis and cartilage. - [S.l.] : Elsevier; Bd. 24.2016, Suppl. 1, Abs. 243, S. S149

Böttcher, Annika;  Stolberg-Stolberg, Josef;  Gronau, Tobias;  Raschke, Michael;  Pap, Thomas;  Bertrand, Jessica 

Role of toll like receptor 3 in cartilage homoeostasis during posttraumatic and degenerative osteoarthritis
In: Osteoarthritis and cartilage. - [S.l.] : Elsevier; Bd. 24.2016, Suppl. 1, Abs. 124, S. S134-S135

Gronau, Tobias;  Hubert, Jan;  Fürst, Martin;  Pap, Thomas;  Bertrand, Jessica 

Shed syndecan-4 in synovial fluid is a marker of osteoarthritis severity
In: Osteoarthritis and cartilage. - [S.l.] : Elsevier; Bd. 24.2016, Suppl. 1, Abs. 124, S. S81

Artikel in Zeitschrift

Harrach, Saliha;  Schmidt-Lauber, Christian;  Pap, Thomas;  Pavenstädt, Hermann;  Schlatter, Eberhard;  Schmidt, Eva;  Berdel, Wolfgang E.;  Schulze, Ulf;  Edemir, Bayram;  Jeromin, Sabine;  Haferlach, Torsten;  Ciarimboli, Giuliano;  Bertrand, Jessica 

MATE1 regulates cellular uptake and sensitivity to imatinib in CML patients
In: Blood cancer journal- London [u.a.]: Nature Publishing Group, 2011, Bd. 6 (2016), Seite e470

Begutachteter Zeitschriftenartikel

Hawellek, T.;  Hubert, J.;  Hischke, S.;  Krause, M.;  Bertrand, J.;  Pap, T.;  Püschel, K.;  Rüther, W.;  Niemeier, A. 

Articular cartilage calcification of the hip and knee is highly prevalent, independent of age but associated with histological osteoarthritis: evidence for a systemic disorder
In: Osteoarthritis and Cartilage, 2016, S. 2092-2099, ISSN 10634584, 10.1016/j.joca.2016.06.020

Hawellek, Thelonius;  Hubert, Jan;  Hischke, Sandra;  Vettorazzi, Eik;  Wegscheider, Karl;  Bertrand, Jessica;  Pap, Thomas;  Krause, Matthias;  Püschel, Klaus;  Rüther, Wolfgang;  Niemeier, Andreas 

Articular cartilage calcification of the humeral head is highly prevalent and associated with osteoarthritis in the general population
In: Journal of Orthopaedic Research, 2016, S. 1984-1990, ISSN 07360266, 10.1002/jor.23227

Hubert, Jan;  Hawellek, Thelonius;  Hischke, Sandra;  Bertrand, Jessica;  Krause, Matthias;  Püschel, Klaus;  Rüther, Wolfgang;  Niemeier, Andreas 

Hyaline cartilage calcification of the first metatarsophalangeal joint is associated with osteoarthritis but independent of age and BMI
In: BMC musculoskeletal disorders - London: BioMed Central, Bd. 17.2016, Art.-Nr. 474, insges. 8 S.

Buchbeitrag

Felson, David T.;  Bertrand, Jessica 

Arthrose
In: Kapitel 321-488: Intensivmedizin, Urologie/Nephrologie, Gastroenterologie, Immunologie, Endokrinologie, Neurologie, Vergiftungen, Umwelteinflüsse - [New York]: McGraw-Hill Education, S. 2737-2745, 2016

2015

Anderes Material

Polte, Tobias;  Petzold, Susanne;  Bertrand, Jessica;  Schütze, Nicole;  Hinz, Denise;  Simon, Jan C;  Lehmann, Irina;  Echtermeyer, Frank;  Pap, Thomas;  Averbeck, Marco 

Critical role for syndecan-4 in dendritic cell migration during development of allergic airway inflammation.
In: Nature communications, Vol. 6, 2015, S. 7554, ISSN 2041-1723, 10.1038/ncomms8554

2014

Begutachteter Zeitschriftenartikel

Sherwood, J.C.;  Bertrand, J.;  Eldridge, S.E.;  Dell'accio, F. 

Cellular and molecular mechanisms of cartilage damage and repair
In: Drug Discovery Today, Vol. 19, 2014, Issue 8, S. 1172-1177, ISSN 13596446, 10.1016/j.drudis.2014.05.014

Höfling, S.;  Scharnert, J.;  Cromme, C.;  Bertrand, J.;  Pap, T.;  Schmidt, M.A.;  Rüter, C. 

Manipulation of pro-inflammatory cytokine production by the bacterial cell-penetrating effector protein YopM is independent of its interaction with host cell kinases RSK1 and PRK2
In: Virulence, Vol. 5, 2014, Issue 7, S. 761-771, ISSN 21505594, 10.4161/viru.29062

2013

Begutachteter Zeitschriftenartikel

Frank, S.;  Peters, M.A.;  Wehmeyer, C.;  Strietholt, S.;  Koers-Wunrau, C.;  Bertrand, J.;  Heitzmann, M.;  Hillmann, A.;  Sherwood, J.;  Seyfert, C.;  Gay, S.;  Pap, T. 

Regulation of matrixmetalloproteinase-3 and matrixmetalloproteinase-13 by SUMO-2/3 through the transcription factor NF-κB
In: Annals of the Rheumatic Diseases, Vol. 72, 2013, Issue 11, S. 1874-1881, ISSN 00034967, 10.1136/annrheumdis-2012-202080

Bertrand, J.;  Stange, R.;  Hidding, H.;  Echtermeyer, F.;  Nalesso, G.;  Godmann, L.;  Timmen, M.;  Bruckner, P.;  Dell'Accio, F.;  Raschke, M.J.;  Pap, T.;  Dreier, R. 

Syndecan 4 supports bone fracture repair, but not fetal skeletal development, in mice
In: Arthritis and Rheumatism, Vol. 65, 2013, Issue 3, S. 743-752, ISSN 00043591, 10.1002/art.37817

Pap, T.;  Bertrand, J. 

Syndecans in cartilage breakdown and synovial inflammation
In: Nature Reviews Rheumatology, Vol. 9, 2013, Issue 1, S. 43-55, ISSN 17594790, 10.1038/nrrheum.2012.178

Lindemann, O.;  Umlauf, D.;  Frank, S.;  Schimmelpfennig, S.;  Bertrand, J.;  Pap, T.;  Hanley, P.J.;  Fabian, A.;  Dietrich, A.;  Schwab, A. 

TRPC6 regulates CXCR2-mediated chemotaxis of murine neutrophils
In: Journal of Immunology, Vol. 190, 2013, Issue 11, S. 5496-5505, ISSN 00221767, 10.4049/jimmunol.1201502

2012

Begutachteter Zeitschriftenartikel

Bertrand, J.;  Nitschke, Y.;  Fuerst, M.;  Hermann, S.;  Schäfers, M.;  Sherwood, J.;  Nalesso, G.;  Ruether, W.;  Rutsch, F.;  Dell'Accio, F.;  Pap, T. 

Decreased levels of nucleotide pyrophosphatase phosphodiesterase 1 are associated with cartilage calcification in osteoarthritis and trigger osteoarthritic changes in mice
In: Annals of the Rheumatic Diseases, Vol. 71, 2012, Issue 7, S. 1249-1253, ISSN 00034967, 10.1136/annrheumdis-2011-200892

Bertrand, J.;  Pap, T. 

News from the osteoarthritis research [Neues aus der Arthroseforschung]
In: Deutsche Medizinische Wochenschrift, Vol. 137, 2012, Issue 36, S. 1766-1768, ISSN 00120472, 10.1055/s-0032-1305207

Godmann, L.;  Pap, T.;  Bertrand, J. 

Pathogenetic-oriented therapies for osteoarthritis - Are new DMOADS on the way? [Pathogenetisch orientierte therapieansätze bei der osteoarthrose - Sind DMOADs in der pipeline?]
In: Aktuelle Rheumatologie, Vol. 37, 2012, Issue 6, S. 358-365, ISSN 0341051X, 10.1055/s-0032-1314795

Fabian, A.;  Bertrand, J.;  Lindemann, O.;  Pap, T.;  Schwab, A. 

Transient receptor potential canonical channel 1 impacts on mechanosignaling during cell migration.
In: Pflügers Archiv : European journal of physiology, Vol. 464, 2012, Issue 6, S. 623-630, ISSN 14322013

Schmidt-Lauber, C.;  Harrach, S.;  Pap, T.;  Fischer, M.;  Victor, M.;  Heitzmann, M.;  Hansen, U.;  Fobker, M.;  Brand, S.-M.;  Sindic, A.;  Pavenstädt, H.;  Edemir, B.;  Schlatter, E.;  Bertrand, J.;  Ciarimboli, G. 

Transport Mechanisms and Their Pathology-Induced Regulation Govern Tyrosine Kinase Inhibitor Delivery in Rheumatoid Arthritis
In: PLoS ONE, Vol. 7, 2012, Issue 12, ISSN 19326203, 10.1371/journal.pone.0052247

2011

Begutachteter Zeitschriftenartikel

Nalesso, G.;  Sherwood, J.;  Bertrand, J.;  Pap, T.;  Ramachandran, M.;  de Bari, C.;  Pitzalis, C.;  Dell'Accio, F. 

WNT-3A modulates articular chondrocyte phenotype by activating both canonical and noncanonical pathways
In: Journal of Cell Biology, Vol. 193, 2011, Issue 3, S. 551-564, ISSN 00219525, 10.1083/jcb.201011051

2010

Begutachteter Zeitschriftenartikel

Umlauf, D.;  Frank, S.;  Pap, T.;  Bertrand, J. 

Cartilage biology, pathology, and repair
In: Cellular and Molecular Life Sciences, Vol. 67, 2010, Issue 24, S. 4197-4211, ISSN 1420682X, 10.1007/s00018-010-0498-0

Bertrand, J.;  Cromme, C.;  Umlauf, D.;  Frank, S.;  Pap, T. 

Molecular mechanisms of cartilage remodelling in osteoarthritis
In: International Journal of Biochemistry and Cell Biology, Vol. 42, 2010, Issue 10, S. 1594-1601, ISSN 13572725, 10.1016/j.biocel.2010.06.022

2009

Begutachteter Zeitschriftenartikel

Fuerst, M.;  Bertrand, J.;  Lammers, L.;  Dreier, R.;  Echtermeyer, F.;  Nitschke, Y.;  Rutsch, F.;  Schäfer, F.K.W.;  Niggemeyer, O.;  Steinhagen, J.;  Lohmann, C.H.;  Pap, T.;  Rüther, W. 

Calcification of articular cartilage in human osteoarthritis
In: Arthritis and Rheumatism, Vol. 60, 2009, Issue 9, S. 2694-2703, ISSN 00043591, 10.1002/art.24774

Echtermeyer, F.;  Bertrand, J.;  Dreier, R.;  Meinecke, I.;  Neugebauer, K.;  Fuerst, M.;  Lee, Y.J.;  Song, Y.W.;  Herzog, C.;  Theilmeier, G.;  Pap, T. 

Syndecan-4 regulates ADAMTS-5 activation and cartilage breakdown in osteoarthritis
In: Nature Medicine, Vol. 15, 2009, Issue 9, S. 1072-1076, ISSN 10788956, 10.1038/nm.1998

2005

Begutachteter Zeitschriftenartikel

Schulze-Bahr, E.;  Kirchhof, P.;  Eckardt, L.;  Bertrand, J.;  Breithardt, G. 

Gender differences in cardiac arrhythmias
In: Herz, Vol. 30, 2005, Issue 5, S. 390-400, ISSN 03409937, 10.1007/s00059-005-2724-3

Verkerk, A.O.;  Wilders, R.;  Schulze-Bahr, E.;  Beekman, L.;  Bhuiyan, Z.A.;  Bertrand, J.;  Eckardt, L.;  Lin, D.;  Borggrefe, M.;  Breithardt, G.;  Mannens, M.M.A.M.;  Tan, H.L.;  Wilde, A.A.M.;  Bezzina, C.R. 

Role of sequence variations in the human ether-a-go-go-related gene (HERG, KCNH2) in the Brugada syndrome
In: Cardiovascular Research, Vol. 68, 2005, Issue 3, S. 441-453, ISSN 00086363, 10.1016/j.cardiores.2005.06.027

2004

Begutachteter Zeitschriftenartikel

Bertrand, J.;  Altendorf, K.;  Bramkamp, M. 

Amino acid substitutions in putative selectivity filter regions III and IV in KdpA alter ion selectivity of the KdpFABC complex from Escherichia coli
In: Journal of Bacteriology, Vol. 186, 2004, Issue 16, S. 5519-5522, ISSN 00219193, 10.1128/JB.186.16.5519-5522.2004

2003

Begutachteter Zeitschriftenartikel

Bramkamp, M.;  Gaßel, M.;  Herkenhoff-Hesselmann, B.;  Bertrand, J.;  Altendorf, K. 

The Methanocaldococcus jannaschii protein Mj0968 is not a P-type ATPase
In: FEBS Letters, Vol. 543, 2003, Issue 1-3, S. 31-36, ISSN 00145793, 10.1016/S0014-5793(03)00372-7

Kooperationen
Profil
Service
Vita
10/2015Professor for Experimental Orthopaedics, University Hospital Magdeburg
05/2013-10/2015DFG Emmy-Noether Group Leader at the Institute of Experimental Musculoskeletal Medicine, University Hospital Muenster, Germany
10/2011-04/2013Postdoc. fellow: Postdoctoral fellowship of the DFG at the Institute of Experimental Musculoskeletal Medicine, University Hospital Muenster, Germany
10/2010-09/2011Postdoc. fellow: Postdoctoral fellowship of the DFG at the Centre for Experimental Medicine and Rheumatology, Queen Mary, London
2008 -2010Postdoc. fellow: Institute of Experimental Musculoskeletal Medicine, University Hospital Muenster, Germany
2004 - 2007Ph.D.-thesis:  "Pathomechanisms of potassium channel (HERG-) Mutations causing the LQT 2 syndrome am Leibniz-Institute for Arteriosklerosis Reserarch (LIFA) at the University of Muenster, Germany
2002-2003Undergradute research at the Department of Microbiology, University of Osnabrueck, Germany
1997-2002Diploma (Biology): "Amino acid substitutions in putative selectively filter regions III and IV in KdpA of the KdpFABC coplex from Escherichia coli am Department of Microbiology, University of Osnabrueck, Germany
Presse
Prof. Dr. rer. nat. Jessica Bertrand, Jahrgang 1978, wurde zum 12. Oktober 2015 auf die W2-Professur für Experimentelle Orthopädie an der Otto-von-Guericke-Universität berufen. An der Orthopädischen Universitätsklinik wird sie künftig den Forschungsbereich Experimentelle Orthopädie leiten.Der Schwerpunkt der Forschungsarbeit von Prof. Bertrand richtet sich auf die Untersuchung der molekularen Mechanismen der Knorpel-Remodellierung unter physiologischen und pathologischen Bedingungen. Dies umfasst die Mechanismen der enchondralen Ossifikation und pathologischen Prozesse, wie Osteoarthrose, Frakturheilung und rheumatoide Arthritis. Die Kernhypothese ihrer Arbeit ist, dass es zu einer erneuten Aktivierung embryonaler Signalkaskaden kommt, die sowohl während der Frakturheilung, als auch der Osteoarthrose aktiv sind und denen der enochondralen Ossifikation in der Embryonalentwicklung in großen Teilen gleichen.