Prof. Amthauer

Prof. Dr. med. Holger Amthauer
Medizinisches Versorgungszentrum Universitätsklinikum Magdeburg gGmbH (MVZ)
Abgeschlossene Projekte
- OPTIMAL>60 Verbesserung der Therapieergebnisse und Verminderung der Nebenwirkungen bei älteren Patienten mit CD20+ aggressivenB-Zell-Lymphomen
Laufzeit: 01.10.2013 - 28.09.2018 - RAPSODY - Messung der Strahlenbelastung von Angehörigen und Pflegekräften bei der ambulanten Behandlung von Patienten mit Radium-223-Dichlorid in Deutschland (RAPSODY)
Laufzeit: 01.10.2013 - 28.09.2018 - Anwendung (ASIR) zur Verminderung der Strahlenexposition in der Hybridbildgebung SPECT/CT
Laufzeit: 01.10.2013 - 28.09.2018 - Einflusses des Lebervolumens auf die Dosierung des Yttrium-90-Radioemboliste
Laufzeit: 01.10.2013 - 28.09.2018 - BroCa_ASP - Aspherizität des prätherapeutischen FDG-Uptakes als unabhängiger Prognosefaktor bei Patienten mit nicht-kleinzelligem Lungenkarzinom
Laufzeit: 01.10.2013 - 28.09.2018 - DELCODE - [18F]-FDG-PET: zur Messung des zerebralen Glucosemetabolismus, [18F]-Flutemetamol-PET: zur Messung der zerebralen Amyloid-beta
Laufzeit: 01.10.2013 - 28.09.2018 - „DEMDAS - DZNE Mechanisms of Dementia after Stroke“ (DEMDAS)
Laufzeit: 01.10.2013 - 28.09.2018 - STIMULATE -> Bildgebung -> Photonendetektion
Laufzeit: 01.03.2013 - 28.02.2014 - Evaluation der Wertigkeit der PET und PET/CT in der pädiatrischen Onkologie.
Laufzeit: 01.12.2008 - 01.01.2010
2019
Begutachteter Zeitschriftenartikel
Impact of combined selective internal radiation therapy and sorafenib on survival in advanced hepatocellular carcinoma
In: Journal of hepatology - Amsterdam [u.a.]: Elsevier Science, Bd. 71.2019, 6, S. 1164-1174
Iterative CT reconstruction in abdominal low-dose CT used for hybrid SPECT-CT applications - effect on image quality, image noise, detectability, and readers confidence
In: Acta radiologica open - London: Sage, Bd. 8.2019, 6, S. 1-9
The association of intra-therapeutic heterogeneity of somatostatin receptor expression with morphological treatment response in patients undergoing PRRT with [177Lu]-DOTATATE
In: PLOS ONE - San Francisco, California, US: PLOS, Bd. 14.2019, 5, Art.-Nr. e0216781, insges. 14 S.
2018
Abstract
The impact of combining Selective Internal Radiation Therapy (SIRT) with sorafenib on overall survival in patients with advanced hepatocellular carcinoma - the SORAMIC trial palliative cohort
In: Annals of oncology - Oxford: Oxford Univ. Press, Bd. 29.2018, O-029, Seite v110
Begutachteter Zeitschriftenartikel
Image quality assessment for low-dose-CT in hybrid SPECT/CT imaging
In: Nuklearmedizin: molecular imaging and therapy - Stuttgart: Thieme, Bd. 57.2018, 4, S. 153-159
JAK2-V617F promotes venous thrombosis through β1/β2 integrin activation
In: The journal of clinical investigation - Ann Arbor, Mich: ASCJ, Bd. 128.2018, 10, S. 4359-4371
Local ablation or radioembolization of colorectal cancer metastases - comorbidities or older age do not affect overall survival
In: BMC cancer - London: BioMed Central, Bd. 18.2018, Art.-Nr. 882, insges. 9 S.
Pre-operative quantification of pulmonary function using hybrid-SPECT/low-dose-CT - a pilot study
In: Lung cancer - Amsterdam [u.a.]: Elsevier, Bd. 118.2018, S. 155-160
Somatostatinrezeptor-PET/CT - Stand: 3/2017 AWMF-Registernummer: 031046
In: Nuklearmedizin: molecular imaging and therapy - Stuttgart: Thieme, Bd. 57.2018, 1, S. 4-17
Urinary excretion of yttrium-90 after radioembolization with yttrium-90-labeled resin-based microspheres
In: Health physics: the radiation safety journal ; official journal of the Health Physics Society - Baltimore, Md.: Lippincott Williams & Wilkins, Bd. 114.2018, 1, S. 58-63
2017
Begutachteter Zeitschriftenartikel
Cytokines and 90Y-radioembolization - relation to liver function and overall survival
In: CardioVascular and interventional radiology: CVIR - Berlin: Springer, Bd. 40.2017, 8, S. 1185-1195
Detektion der obstruktiven Uropathie und Erhebung der seitengetrennten Nierenfunktion mit zwei funktionellen Magnetresonanzurographie-Verfahren - ein Vergleich mit der Nierensequenzszintigraphie bei Säuglingen und Kindern
In: Nuklearmedizin - Stuttgart: Thieme, 1959, Bd. 56.2017, 1, S. 39-46
Extraktion von 223Radium durch Hämodialyse nach Behandlung eines metastasierten kastrationsresistenten Prostatakarzinoms
In: Nuklearmedizin: molecular imaging and therapy - Stuttgart: Thieme, 1959, Bd. 56.2017, 3, S. 69-72
Improvement of image quality and dose management in CT fluoroscopy by iterative 3D image reconstruction
In: European radiology: official organ of the European Association of Radiology - Berlin: Springer, Bd. 27.2017, 9, S. 3625-3634
Position-related renal perfusion disturbances as a possible underestimated mechanism in patients with resistant hypertension - a case vignette
In: International urology and nephrology - Dordrecht [u.a.]: Springer Science + Business Media B.V., 1969, Bd. 49.2017, 10, S. 1823-1833
Predictive value of asphericity in pretherapeutic [111In]DTPA-octreotide SPECT/CT for response to peptide receptor radionuclide therapy with [177Lu]DOTATATE
In: Molecular imaging & biology - Amsterdam [u.a.]: Elsevier Science, Bd. 19.2017, 3, S. 437-445
Proof of therapeutic efficacy of a 177Lu-labeled neurotensin receptor 1 antagonist in a colon carcinoma xenograft model
In: Journal of nuclear medicine - New York, NY: Soc, 1964, Bd. 58.2017, 6, S. 936-941
Software-assisted dosimetry in peptide receptor radionuclide therapy with 177Lutetium-DOTATATE for various imaging scenarios
In: PLOS ONE - San Francisco, California, US: PLOS, 2006, Bd. 12.2017, 11, Art.-Nr. e0187570, insges. 14 S.
Utility of follow-up dopamine transporter SPECT with 123I-FP-CIT in the diagnostic workup of patients with clinically uncertain parkinsonian syndrome
In: Clinical nuclear medicine: CNM - Philadelphia, Pa: Lippincott Williams & Wilkins, Bd. 42.2017, 8, S. 589-594
2016
Abstract
SPECT-imaging of disturbed brain functions in dementia using a lipophilic chelate complex of the K+-probe 201 thallium
In: Journal of cerebral blood flow and metabolism: official journal of the International Society of Cerebral Blood Flow and Metabolism - Thousand Oaks, CA: Sage, 1981, Bd. 36.2016, Suppl. 1, Abs. 198, S. 111-112
Wohin sollten wir unsere Vorlesungen entwickeln? - Auswertung einer Umfrage zu Mediennutzung und Vorlesungsverhalten unter Studierenden in der radiologischen Hauptvorlesung der Universität Magdeburg
In: RöFo : Fortschritte auf dem Gebiet der Röntgenstrahlen und der bildgebenden Verfahren. - Stuttgart [u.a.] : Thieme; Bd. 188.2016, S01, Abs. WISS308_5, insges. 1 S.
Y90 Radioembolisation bei Patienten mit chemorefraktärem, leberdominanten kolorektalen Karzinom - Entwicklung eines prognostischen Scores
In: RöFo: Fortschritte auf dem Gebiet der Röntgenstrahlen und der bildgebenden Verfahren - Stuttgart [u.a.]: Thieme, Bd. 188.2016, S01, Abs. WISS310_6, insges. 1 S.
Begutachteter Zeitschriftenartikel
An investigation of the relation between tumor-to-liver ratio (TLR) and tumor-to-blood standard uptake ratio (SUR) in oncological FDG PET
In: EJNMMI Research - Berlin: Springer, 2011, Bd. 6, 2016, Art.-Nr. 19, insges. 9 S.
Drs. Grosser et al respond - letter to the editor
In: Journal of vascular and interventional radiology: JVIR ; official journal of the Society of Cardiovascular and Interventional Radiology - Amsterdam [u.a.]: Elsevier, 1990, Bd. 27.2016, 2, S. 297-298
Dual time point imaging for F18-FDG-PET/CT does not improve the accuracy of nodal staging in non-small cell lung cancer patients
In: European radiology - Berlin: Springer, 1991, Bd. 26.2016, 8, S. 2808-2818
Extensive use of interventional therapies improves survival in unresectable or recurrent intrahepatic cholangiocarcinoma
In: Gastroenterology research and practice - New York, NY: Hindawi, 2008, 2016, Art.-ID 8732521, insges. 13 S.
Pharmacokinetics of 99mTc-MAA- and 99mTc-HSA-microspheres used in preradioembolization dosimetry - influence on the liverlung shunt
In: Journal of nuclear medicine: JNM - New York, NY: Soc, 1964, Bd. 57.2016, 6, S. 925-927
SPECT/CT demonstrates the osseointegrative response of a stemless shoulder prosthesis
In: Journal of shoulder and elbow surgery - St. Louis, Mo.: Mosby, Bd. 25.2016, 4, S. e96-e103
Significance of a single-time-point somatostatin receptor SPECT/multiphase CT protocol in the diagnostic work-up of gastroenteropancreatic neuroendocrine neoplasms
In: Journal of nuclear medicine: JNM - New York, NY: Soc, 1964, Bd. 57.2016, 2, S. 180-185
Standardized visual reading of F18-FDG-PET in patients with non-small cell lung cancer scheduled for preoperative thoracic lymph node staging
In: European journal of radiology - Amsterdam [u.a.]: Elsevier Science, 1990, Bd. 85.2016, 8, S. 1345-1350
The asphericity of the metabolic tumour volume in NSCLC - correlation with histopathology and molecular markers
In: European journal of nuclear medicine and molecular imaging: official journal of the European Association of Nuclear Medicine (EANM)- Heidelberg [u.a.]: Springer-Verl, 2002, Bd. 43.2016, 13, S. 2360-2373
Y90 Radioembolization in chemo-refractory metastastic, liver dominant colorectal cancer patients - outcome assessment applying a predictive scoring system
In: BMC cancer - London: BioMed Central, Bd. 16.2016, Art.-Nr. 509, insges. 7 S.
Buchbeitrag
Illustrative PET/CT visualisation of SIRT-treated lung metastases
In: VCBM 16: Eurographics Workshop on Visual Computing for Biology and Medicine - Eurographics Ass., 2016 . - 2016
Habilitation
Die Sicherheit und Effektivität der bildgeführten, isotopen-basierten Mikrotherapie der Leber
In: Magdeburg: Otto-von-Guericke-Universität Magdeburg, 2016, verschiedene Seitenzählung, Illustrationen, Diagramme
2015
Abstract
Added value of follow-up FP-CIT SPECT in clinical routine
In: Journal of nuclear medicine: JNM : official publ. of the Society of Nuclear Medicine - Reston, Va: SNM, Bd. 56.2015, Suppl. 3, Abs. 1579, insges. 1 S.
Correlation of SUV and tumor to blood standard uptake ratio (SUR) with the metabolic uptake rate derived from quantitative dual time point measurements
In: European journal of nuclear medicine & molecular imaging: official organ of the European Association of Nuclear Medicine (EANM): official journal of the European Association of Nuclear Medicine (EANM) - Berlin: Springer, 1976, Bd. 42.2015, Suppl. 1, OP163, S. S70-S71
Reduced thalamic FDG uptake in adults with neurofibromatosis type 1
In: Journal of nuclear medicine: JNM : official publ. of the Society of Nuclear Medicine - Reston, Va: SNM, Bd. 56.2015, Suppl. 3, Abs. 1608, insges. 1 S.
Begutachteter Zeitschriftenartikel
Cerebral glucose metabolism in adults with neurofibromatosis type 1
In: Brain research: an international multidisciplinary journal devoted to fundamental research in the brain sciences - Amsterdam: Elsevier, Bd. 1625 (2015), S. 97-101
FDG-PET response prediction in pediatric Hodgkinʾs lymphoma - Impact of metabolically defined tumor volumes and individualized SUV measurements on the positive predictive value
In: Cancers - Basel: MDPI, Bd. 7 (2015), 1, S. 287-304
Hybrid SPECT/CT for the assessment of a painful hip after uncemented total hip arthroplasty
In: BMC medical imaging - London: BioMed Central, Bd. 15.2015, Art.-Nr. 18, insges. 10 S.
Intrahepatic activity distribution in radioembolization with yttrium-90-labeled resin microspheres using the body surface area method - a less than perfect model
In: Journal of vascular and interventional radiology: JVIR ; official journal of the Society of Cardiovascular and Interventional Radiology - Amsterdam [u.a.]: Elsevier, Bd. 26 (2015), 11, S. 1615-1621
Locally ablative treatment of breast cancer liver metastases: identification of factors influencing survival (the Mammary Cancer Microtherapy and Interventional Approaches (MAMMA MIA) study)
In: BMC cancer - London: BioMed Central, Bd. 15.2015, Art.-Nr.517, insges. 12 S.
Optimization of SPECT-CT hybrid imaging using iterative image reconstruction for low-dose CT - a phantom study
In: PLOS ONE - San Francisco, California, US: PLOS, Bd. 10.2015, 9, Art.-Nr. e0138658, insges. 15 S.
Peptidrezeptor-Radionuklidtherapie Somatostatinrezeptor-exprimierender Tumore - DGN-Leitlinie (S1) =Peptide receptor radionuclide therapy for patients with somatostatin receptor expressing tumours
In: Nuklearmedizin <Stuttgart, 1959/61 - 1983; 1988 ->: molecular imaging and therapy ; Verbandsorgan der DGN, ÖGN, SGNM, SSNM - Stuttgart: Thieme, Bd. 54.2015, 1, S. 1-11
Perfusion single photon emission computed tomography in a mouse model of neurofibromatosis type 1 - towards a biomarker of neurologic deficits
In: Journal of cerebral blood flow &amp; metabolism: JCBFM : official journal of the International Society of Cerebral Blood Flow and Metabolism - Thousands Oaks, Calif: Sage, Bd. 35.2015, 8, S. 1304-1312
The association of tumor-to-background ratios and SUVmax deviations related to point spread function and time-of-flight F18-FDG-PET/CT reconstruction in colorectal liver metastases
In: EJNMMI Research - Berlin: Springer, Bd. 5.2015, Art.-Nr. 31, insges. 9 S.
Time course of contrast enhancement by micro-CT with dedicated contrast agents in normal mice and mice with hepatocellular carcinoma - Comparison of one iodinated and two nanoparticle-based agents
In: Academic radiology - Philadelphia, PA [u.a.]: Elsevier, Bd. 22 (2015), 2, S. 169-178
Habilitation
Therapiemonitoring von malignen Lymphomen im Kindes- und Jugendalter mittels FDG-PET - prognostische Relevanz von visuellen und semi-quantitativen Befundungsparametern : [kumulative Habilitation]
In: Magdeburg, Univ., Med. Fak., Habil.-Schr., 2015, Getr. Zählung, Ill., graph. Darst.
2014
Abstract
Reduction of radiation exposure using adaptive statistical iterative reconstruction (ASIR) in SPECT-CT
In: European journal of nuclear medicine &amp; molecular imaging : official organ of the European Association of Nuclear Medicine (EANM). - Berlin : Springer; Bd. 41.2014, Suppl.2, P014, S. S362
Artikel in Zeitschrift
Assessment of tumor size reduction improves outcome prediction of positron emission tomography/computed tomography after chemotherapy in advanced-stage Hodgkin lymphoma
In: Journal of clinical oncology: JCO ; official journal of the American Society of Clinical Oncology - Alexandria, Va.: American Society of Clinical Oncology, 1983, Bd. 32.2014, 17, S. 1776-1781
Begutachteter Zeitschriftenartikel
Asphericity of pretherapeutic tumour FDG uptake provides independent prognostic value in head-and-neck cancer
In: European radiology: official organ of the European Association of Radiology - Berlin: Springer, Bd. 24.2014, 9, S. 2077-2087
General theory of predictive dosimetry for yttrium-90 radioembolization to sites other than the liver - Reply
In: CardioVascular &amp; interventional radiology. - Berlin : Springer, Bd. 37.2014, 4, S. 1120-1121
Globale Skalierung des Tracer-Uptakes für die semi-quantitative Analyse in der FP-CIT SPECT
In: Nuklearmedizin - Stuttgart: Thieme, 1959, Bd. 53.2014, 6, S. 234-241
Left-liver hypertrophy after therapeutic right-liver radioembolization is substantial but less than after portal vein embolization
In: Hepatology: official journal of the American Association for the Study of Liver Diseases - New York [u.a.]: Wiley Interscience, Bd. 59.2014, 5, S. 1864-1873
Pretreatment dosimetry in HCC radioembolization with 90Y glass microspheres cannot be invalidated with a bare visual evaluation of 99mTc-MAA uptake of colorectal metastases treated with resin microspheres - Reply. Letters to the editor
In: Journal of nuclear medicine: JNM - New York, NY: Soc, Bd. 55.2014, 7, S. 1216-1218
Quantitative assessment of the asphericity of pretherapeutic FDG uptake as an independent predictor of outcome in NSCLC
In: BMC cancer - London: BioMed Central, Bd. 14.2014, Art.-Nr. 896, insges. 10 S.
SPECT-imaging of activity-dependent changes in regional cerebral blood flow induced by electrical and optogenetic self-stimulation in mice
In: NeuroImage: a journal of brain function - Orlando, Fla: Academic Press, Bd. 103.2014, S. 171-180
Safety of repeated radioembolizations in patients with advanced primary and secondary liver tumors and progressive disease after first selective internal radiotherapy
In: Journal of nuclear medicine - New York, NY: Soc, 1964, Bd. 55.2014, 3, S. 360-366
The influence of different signal-to-background ratios on spatial resolution and F18-FDG-PET quantification using point spread function and time-of-flight reconstruction
In: EJNMMI Physics - Berlin: Springer Open, 2014, Bd. 1.2014, Art.-Nr. 12, insges. 16 S.
Tumor cell uptake of 99mTc-labeled 1-thio-[beta]-D-glucose and 5-thio-D-glucose in comparison with 2-deoxy-2-[18F]fluoro-D-glucose in vitro - kinetics, dependencies, blockage and cell compartment of accumulation
In: Molecular imaging &amp; biology: MIB : the official journal of the Academy of Molecular Imaging - Amsterdam [u.a.]: Elsevier Science, Bd. 16.2014, 2, S. 189-198
2013
Abstract
Bildgesteuerte HDR-Brachytherapie von Nierenmalignomen und nierennah gelegenen Metastasen - Evaluation der Nierentoleranzdosis
In: RöFo - Stuttgart [u.a.]: Thieme, 1949, Bd. 185.2013, Nr. S1, VO319_4, insges. 1 S.
Safety and toxicity of the combination of Y90-radioembolization and sorafenib in advanced HCC - An interim analysis of the European multicenter trial soramic
In: Journal of hepatology: the home of liver research - Amsterdam: Elsevier, 1985, Bd. 58.2013, Suppl.1, Abs.268, S. S114
Begutachteter Zeitschriftenartikel
Efficacy of diphenhydramine in the prevention of vertigo and nausea at 7 T MRI
In: European journal of radiology: EJR - Shannon: Elsevier Science Ireland Ltd., 1981, Bd. 82.2013, 5, S. 768-772
Explorative analyses on the value of interim PET for prediction of response in pediatric and adolescent non-Hodgkin lymphoma patients
In: EJNMMI Research - Berlin: Springer, 2011, Bd. 3.2013, Art.-Nr. 71, insges. 11 S.
Influence of rigid coregistration of PET and CT data on metabolic volumetry - user's perspective
In: EJNMMI Research - Berlin: Springer, 2011, Bd. 3.2013, Art.-Nr. 85, insges. 9 S.
Interim-PET bei Kindern und Jugendlichen mit Non-Hodgkin-Lymphom - Ergebnisse einer retrospektiven, multizentrischen Auswertung
In: Nuklearmedizin - Stuttgart: Thieme, 1959, Bd. 52.2013, 4, S. 148-156
Multiparameter analysis of serum levels of C-telopeptide crosslaps, bone-specific alkaline phosphatase, cathepsin K, osteoprotegerin and receptor activator of nuclear factor [kappa]B ligand in the diagnosis of osteoporosis
In: Maturitas - Amsterdam [u.a.]: Elsevier Science, 1978, Bd. 74.2013, 4, S. 363-368
Predictive value of intratumoral 99mTc-macroaggregated albumin uptake in patients with colorectal liver metastases scheduled for radioembolization with 90Y-microspheres
In: Journal of nuclear medicine: JNM ; official publ. of the Society of Nuclear Medicine / ed. Belton A. Burrows: JNM ; official publ. of the Society of Nuclear Medicine - Reston, Va.: SNM, 1959, Bd. 54.2013, 4, S. 516-522
Präventive Knochendichtemessung bei postmenopausalen Frauen - Differenzierung der Therapieempfehlungen der Leitlinien des Dachverbandes Osteologie (DVO)
In: Der Unfallchirurg - Berlin: Springer, 1996, Bd. 116.2013, 7, S. 596-601
Quantification in 68Ga-DOTA(0)-Phe(1)-Tyr(3)-octreotide positron emission tomography/computed tomography - can we be impartial about partial volume effects?
In: Neuroendocrinology: international journal for basic and clinical studies on neuroendocrine relationships ; official organ of the International Society of Neuroendocrinology - Basel: Karger, 1965, Bd. 97.2013, 4, S. 369-374
Results confounded by a disregard for basic doseresponse radiobiology - Reply. Letters to the editor
In: Journal of nuclear medicine - New York, NY: Soc, 1964, Bd. 54.2013, 9, S. 1683-1684
Value of 99mTc-macroaggregated albumin SPECT for radioembolization treatment planning - Reply. Letters to the editor
In: Journal of nuclear medicine - New York, NY: Soc, 1964, Bd. 54.2013, 9, S. 1682
Y90-radioembolization of lung metastases via the bronchial artery - a report of 2 cases
In: CardioVascular and interventional radiology - Berlin: Springer, 1978, Bd. 36.2013, 6, S. 1664-1669
2012
Originalartikel in begutachteter internationaler Zeitschrift
Effectiveness of repeat angiographic assessment in patients designated for radioembolization using yttrium-90 microspheres with initial extrahepatic accumulation of technitium-99m macroaggregated albumin - a single center's experience
In: CardioVascular and interventional radiology: CVIR ; the official journal of the CardioVascular and Interventional Radiological Society of Europe - New York, NY: Springer, Bd. 35 (2012), 5, S. 1083-1093
Estimation of return-to-sports-time for athletes with stress fracture: an approach combining risk level of fracture site with severity based on imaging
In: BMC musculoskeletal disorders - London: BioMed Central, Bd. 13.2012, Art.-Nr.139, insges. 7 S.
Evaluation of functional MR-urography in complex obstructive uropathy of infants: comparison to the conventional diagnostic algorithm: A pilot study
In: Klinische Pädiatrie: clinical research and practice in pediatrics - Stuttgart: Thieme, 1972, Bd. 224.2012, 5, S. 296-302
Hepatic toxicity after radioembolization of the liver using 90Y-microspheres - sequential lobar versus whole liver approach
In: CardioVascular and interventional radiology: CVIR ; the official journal of the CardioVascular and Interventional Radiological Society of Europe - New York, NY: Springer, 1980, Bd. 35.2012, 5, S. 1109-1118
Matched-pair comparison of radioembolization plus best supportive care versus supportive care alone for chemotherapy refractory liver-dominant colorectal metastases
In: CardioVascular and interventional radiology: CVIR ; the official journal of the CardioVascular and Interventional Radiological Society of Europe - New York, NY: Springer, Bd. 35 (2012), 5, S. 1066-1073
SUV-measurements and patient-specific corrections in pediatric Hodgkin-lymphoma: Is there a benefit for PPV in early response assessment by FDG-PET?
In: Pediatric blood &amp; cancer: official journal of the International Society of Paediatric Oncology, the American Society of Pediatric Hematology, Oncology, the Histiocyte Society - Hoboken, NJ: Wiley-Liss, Bd. 59 (2012), 3, S. 475-480
Serum Cathepsin K levels are not suitable to differentiate women with chronic bone disorders such as osteopenia and osteoporosis from healthy pre- and postmenopausal women
In: Maturitas: the European menopause journal - Amsterdam: Elsevier/North-Holland Biomed Press, 1978, Bd. 71.2012, 2, S. 169-172
Originalartikel in begutachteter nationaler Zeitschrift
Vergleich von MRT und Skelettszintigraphie zur Diagnose und Gradeinteilung von Stressfrakturen
In: Nuklearmedizin: molecular imaging and therapy ; Verbandsorgan der DGN, ÖGN, SGNM, SSNM / Hrsg. Deutsche Gesellschaft für Nuklearmedizin (DGN), Österreichische Gesellschaft für Nuklearmedizin (ÖGN), Schweizerische Gesellschaft für Nuklearmedizin (SGNM, SSNM): molecular imaging and therapy ; Verbandsorgan der DGN, ÖGN, SGNM, SSNM - Stuttgart: Thieme, Bd. 51 (2012), 3, S. 88-94
2011
Originalartikel in begutachteter internationaler Zeitschrift
68Ga-DOTATOC PET/CT of neuroendocrine tumors: spotlight on the CT phases of a triple-phase protocol
In: Journal of nuclear medicine: JNM ; official publ. of the Society of Nuclear Medicine / ed. Belton A. Burrows: JNM ; official publ. of the Society of Nuclear Medicine - Reston, Va.: SNM, 1959, Bd. 52.2011, 5, S. 697-704
99mTc-besilesomab (Scintimun) in peripheral osteomyelitis: comparison with 99mTc-labelled white blood cells
In: European journal of nuclear medicine &amp; molecular imaging: official organ of the European Association of Nuclear Medicine (EANM) - Berlin: Springer, 1976, Bd. 38.2011, 5, S. 899-910
Blinded-read of bone scintigraphy: the impact on diagnosis and healing time for stress injuries with emphasis on the foot
In: Clinical nuclear medicine - Philadelphia, Pa.: Lippincott Williams &amp; Wilkins, 1976, Bd. 36.2011, 3, S. 186-191
Embolization of the gastroduodenal artery before selective internal radiotherapy - a prospectively randomized trial comparing standard pushable coils with fibered interlock detachable coils
In: CardioVascular and interventional radiology: CVIR ; the official journal of the CardioVascular and Interventional Radiological Society of Europe - New York, NY: Springer, 1980, Bd. 34.2011, 1, S. 74-80
Evaluation of interim PET response criteria in paediatric Hodgkin's lymphoma - results for dedicated assessment criteria in a blinded dual-centre read
In: Annals of oncology: official journal of the European Society for Medical Oncology and the Japanese Society of Medical Oncology: driving innovation in oncology : an official journal of the European Society for Medical Oncology and the Japanese Society of Medical Oncology - Oxford: Elsevier, 1990, Bd. 22.2011, 5, S. 1198-1203
Midbrain serotonin transporters in de novo and L-DOPA-treated patients with early Parkinsons̕ disease - a [123I]-ADAM SPECT study
In: European journal of neurology: the official journal of the European Federation of Neurological Societies - Oxford: Blackwell Science, 1994, Bd. 18.2011, 5, S. 750-755
Radioembolisation mit 90Y-markierten Mikrosphären: Posttherapeutische Therapievalidierung mit Bremsstrahlungs-SPECT
In: Zeitschrift für medizinische Physik: Zeitschrift der DGMP; ÖGMP und SGSMP / Hrsg.: Deutsche Gesellschaft für Medizinische Physik ; Österreichische Gesellschaft für Medizinische Physik ; Schweizerische Gesellschaft für Strahlenbiologie und Medizinische Physik: Zeitschrift der DGMP; ÖGMP und SGSMP - Amsterdam: Elsevier, Urban &amp; Fischer, 1991, Bd. 21.2011, 4, S. 274-280
2010
Originalartikel in begutachteter internationaler Zeitschrift
Assessment of histological response of paediatric bone sarcomas using FDG PET in comparison to morphological volume measurement and standardized MRI parameters
In: European journal of nuclear medicine &amp; molecular imaging . - Berlin : Springer, Bd. 37.2010, 10, S. 1842-1853
Clinical role of anti-granulocyte MoAb versus radiolabeled white blood cells
In: The quarterly journal of nuclear medicine and molecular imaging: official publication of the Italian Association of Nuclear Medicine (AIMN), the International Association of Radiopharmacology (IAR), Section of the Society of Radiopharmaceutical Chemistry and Biology - Torino: Ed. Minerva Medica, Bd. 54 (2010), 6, S. 599-616
Early prediction of anticancer effects with diffusion-weighted MR imaging in patients with colorectal liver metastases following selective internal radiotherapy
In: European radiology: journal of the European Congress of Radiology (ECR) ; official organ of the European Association of Radiology: official journal of the European Congress of Radiology - Berlin: Springer, Bd. 20 (2010), 11, S. 2699-2706
Impact of multiphase 68Ga-DOTATOC-PET/CT on therapy management in patients with neuroendocrine tumors
In: Neuroendocrinology: international journal for basic and clinical studies on neuroendocrine relationships ; official organ of the International Society of Neuroendocrinology - Basel: Karger, 1965, Bd. 91.2010, 1, S. 101-109
Serotonergic neurotransmission in early Parkinson's disease: A pilot study to assess implications for depression in this disorder
In: The world journal of biological psychiatry: the official journal of the World Federation of Societies of Biological Psychiatry - London: Informa Healthcare, Bd. 11 (2010), 6, S. 781-787
Value of combined PET/CT for radiation planning in CT-guided percutaneous interstitial high-dose-rate single-fraction brachytherapy for colorectal liver metastases
In: International journal of radiation oncology, biology, physics / sponsored by the American Society of Therapeutic Radiologists - New York, NY [u.a.]: Elsevier, Bd. 77 (2010), 4, S. 1178-1185
Originalartikel in begutachteter nationaler Zeitschrift
Empfehlungen zur Durchführung der Ganzkörper-18F-FDG-PET und -PET/CT bei Kindern mit onkologischen Erkrankungen - Anpassung der EANM-Guideline an aktuelle Gegebenheiten in Deutschland
In: Nuklearmedizin: molecular imaging and therapy ; Verbandsorgan der DGN, ÖGN, SGNM, SSNM / Hrsg. Deutsche Gesellschaft für Nuklearmedizin (DGN), Österreichische Gesellschaft für Nuklearmedizin (ÖGN), Schweizerische Gesellschaft für Nuklearmedizin (SGNM, SSNM): molecular imaging and therapy ; Verbandsorgan der DGN, ÖGN, SGNM, SSNM - Stuttgart: Thieme, Bd. 49 (2010), 6, S. 225-233
Spezielle Therapiesituationen beim metastasierten kolorektalen Karzinom
In: Onkologie . - Basel : Karger, Bd. 33.2010, S. 8-18
2009
Originalartikel in begutachteter internationaler Zeitschrift
Attenuation correction of somatostatin receptor SPECT by integrated low-dose CT: is there an impact on sensitivity?
In: Clinical nuclear medicine - Philadelphia, Pa.: Lippincott Williams &amp; Wilkins, Bd. 34 (2009), 12, S. 869-873
Early and late therapy response assessment with [18F]fluorodeoxyglucose positron emission tomography in pediatric Hodgkin's lymphoma: analysis of a prospective multicenter trial
In: Journal of clinical oncology: JCO ; official journal of the American Society of Clinical Oncology: JCO : an American Society of Clinical Oncology journal - Alexandria, Va.: American Society of Clinical Oncology, Bd. 27 (2009), 26, S. 4385-4391
Hepatocellular carcinoma and liver cirrhosis: assessment of the liver function after yttrium-90 radioembolization with resin microspheres or after CT-guided high-dose-rate brachytherapy
In: Digestive diseases . - Basel : Karger, Bd. 27.2009, 2, S. 189-199
2008
Originalartikel in begutachteter internationaler Zeitschrift
Planning transarterial radioembolization of colorectal liver metastases with Yttrium 90 microspheres: evaluation of a sequential diagnostic approach using radiologic and nuclear medicine imaging techniques
In: European radiology: journal of the European Congress of Radiology (ECR) ; official organ of the European Association of Radiology: official journal of the European Congress of Radiology - Berlin: Springer, Bd. 18 (2008), 5, S. 892-902
Originalartikel in begutachteter nationaler Zeitschrift
Incidental detection of breast cancer by 68Ga-DOTATOC-PET/CT in women suffering from neureoendocrine tumours
In: Nuklearmedizin: molecular imaging and therapy ; Verbandsorgan der DGN, ÖGN, SGNM, SSNM / Hrsg. Deutsche Gesellschaft für Nuklearmedizin (DGN), Österreichische Gesellschaft für Nuklearmedizin (ÖGN), Schweizerische Gesellschaft für Nuklearmedizin (SGNM, SSNM): molecular imaging and therapy ; Verbandsorgan der DGN, ÖGN, SGNM, SSNM - Stuttgart: Thieme, Bd. 47 (2008), 6, S. 261-265
2007
Originalartikel in begutachteter internationaler Zeitschrift
Assessment of local control after laser-induced thermotherapy of liver metastases from colorectal cancer - contribution of FDG-PET in patients with clinical suspicion of progressive disease
In: Acta radiologica . - Stockholm : Informa Healthcare, Bd. 48.2007, 8, S. 821-830
Evaluation of patients with liver metastases from colorectal cancer for locally ablative treatment with laser induced thermotherapy - Impact of PET with 18F-fluorodeoxyglucose on therapeutic decisions
In: Nuklearmedizin 2006 45 4: 177-184.
- Dr. Kahl Klinikum Magdeburg
- Prof. Schostak, Klinik für Urologie der Universität Magdeburg
- Prof. Emrah Düzel, Institut für Kognitive Neurologie und Demenzforschung
Prof. Dr. med. Holger Amthauer
Adresse (dienstlich):Klinik für Radiologie und Nuklearmedizin
Bereich Nuklearmedizin
Universitätsklinikum Magdeburg A.ö.R.
Leipziger Straße 44
D-39120 Magdeburg
Tel.: 0391/67-13000 Fax: 0391/67-13016
e-mail:
Alter:43
Dienststellung/Position:Von August 2000 bis Juli 2006 Leitender Oberarzt Leiter Ambulanzzentrum Campus Virchow-Klinikum GmbH, Fachgebiet Nuklearmedizin
Ab 01. Juli 2008: Leiter Bereich Nuklearmedizin
Universitätsklinikum Magdeburg A.ö.R.
Ausbildung/Qualifikation:
- Studium Humanmedizin in Budapest, Giessen und München (Technische Universität ) von 1986-1993
- Promotion "Nukleolus organisierende Regionen (NORs) in neuroendokrinen Tumoren des Magen-Darm-Traktes und Pankreas: Korrelation mit histopathologischen und klinischen Daten" (Univ.-Prof. Dr. H. Höfler, Institut für Pathologie, Klinikum rechts der Isar der TU München)
Prädikat: "magna cum laude" / 1998
- Habilitation und Lehrbefugnis Verbesserung der Lokalisationsdiagnostik in der Einzel-Photonen-Emissionscomputertomographie (SPECT) durch Koregistrierung mit anatomischer Schnittbildgebung: Klinische Validierung.
Lehrbefugnis und Lehrbefähigung Nuklearmedizin
Seit: 13.11.2006
- Fachliche Qualifikation - Arzt für Nuklearmedizin
- Fachkunde Radiolog. Diagnostik inkl. Computertomographie
- Fachkunde Magnetresonanztomographie
- Strahlenschutzbeauftrager
Schwerpunkte:
- Forschung- Integrierte Bildgebung mittels SPECT-CT und PET-CT in der Onkologie
- Entwicklung neuer Algorithmen in der Diagnostik von malignen Erkrankungen im Kindes- und Jugendalter
- Diagnostik und Therapie von neuroendokrinen Tumoren
- Anwendung nuklearmed. Verfahren zur Therapieplanung in der Mikrotherapie und Radioonkologie
- Anwendung von innovativen Radiopharmazeutika in der Diagnostik von neurodegenerativen Erkrankungen und in der Neuroonkologie
- Aufbau eines Zentrums für Molekulare Bildgebung im Kleintierbereich
- Krankenversorgung - Aufbau Ambulanzzentrum Fachgebiet Nuklearmedizin und PET-CT;
- Integration der ambulanten und stationären Versorgung
- Etablierung neuer nuklearmedizinischer Therapieverfahren (Radiorezeptortherapie, Radioimmuntherapie, minimal invasive Radionuklidtherapie)
- Diagnostik neurodegenerativer Erkrankungen und Neuroonkologie
- Leitender Oberarzt Bereich Nuklearmedizin, Klinik für Strahlenheilkunde, Campus Virchow-Klinikum, Charité, Berlin
- Leiter Ambulanzzentrum Fachgebiet Nuklearmedizin, Campus Virchow-Klinikum GmbH, Charité, Berlin
- Leitungstätigkeit- Leitender Oberarzt Bereich Nuklearmedizin, Klinik für Strahlenheilkunde, Campus Virchow-Klinikum, Charité, Berlin
- Leiter Ambulanzzentrum Fachgebiet Nuklearmedizin, Campus Virchow-Klinikum GmbH, Charité, Berlin
Publikationen: - Originalarbeiten insgesamt: 67
In den letzten fünf Jahren: 56
- Erst- und Letztautor:19
- Übersichtsarbeiten: 4
Sonstiges:- Hospitation PET-Centre Hammersmith Hospital, London
- Förderpreis der Berlin-Brandenburgischen Gesellschaft für Nuklearmedizin 2004
- Mitglied diverser nationaler und internationaler Fachgesellschaften (BBGN, DGN, EANM, NETworks...)
- Gutachtertätigkeit für "European Journal of Nuclear Medicine and Molecular Imaging", "Journal of Nuclear Medicine" und "European Radiology"
Magdeburg 04. Juni 2008Amthauer