Prof. Relja

Prof. Dr. phil. nat. Borna Relja
Aktuelle Projekte
- Forschungscampus STIMULATE - Querschnittsthema Immunoprofiling
Laufzeit: 01.10.2020 - 30.09.2025 - Einfluss des Alters und der Alkoholintoxikation auf die Frakturheilung und das regenerative Potential nach Trauma-Hämorrhagie im murinen Tiermodell
Laufzeit: 07.05.2018 - 30.09.2023 - Project 10: Maladaptation of the hepatic barrier in alcohol-induced liver injury within the RTG 2408: Maladaptive Prozesse an physiologischen Grenzflächen bei chronischen Erkrankungen
Laufzeit: 01.04.2020 - 31.03.2023
Abgeschlossene Projekte
- Die pathophysiologische Bedeutung des Club Cell Protein 16 bei der Entstehung respiratorischer Komplikationen - Analyse eines klinischen Kombinationsmodells von Thoraxtrauma und ARDS unter besonderer Berücksichtigung der Funktion neutrophiler Granulozyten
Laufzeit: 01.01.2018 - 31.01.2021 - Modulation der akuten Entzündungsantwort und der hepato-pulmonalen Organdysfunktion durch Alkohol und Ethylpyruvat in einem klinisch relevanten Kombinationsmodell von hämorrhagischem Schock und Thoraxtrauma unter besonderer Berücksichtigung NF-KappaB-vermittelter Pathomechanismen.
Laufzeit: 01.12.2014 - 31.12.2020
2020
Abstract
Acute alcohol intoxication of healthy volunteers modulates monocyte subsets and their functions in dose- and time-dependent manner
In: Shock: injury, inflammation, and sepsis, laboratory and clinical approaches - Hagerstown, Md.: Lippincott, Williams & Wilkins, 1994, Vol. 53.2020, Suppl. 1, P154, S. 89
DAMP-mediated cardiac dysfunction - cardiomyocytes as actors and target of innate immune response
In: The journal of immunology - Bethesda, Md.: Soc., 1916, Vol. 204.2020, Suppl. 1, 144.18
Trauma-hemorrhage - mitochondrial dysfunction, autophagy and apoptosis in pig liver 72 h post polytrauma
In: Zeitschrift für Orthopädie und Unfallchirurgie: Organ der Deutschen Gesellschaft für Orthopädie und Orthopädische Chirurgie - Stuttgart [u.a.]: Thieme, 2007, Bd. 158.2020, Suppl. 1, DKOU20-150, S. S30-S31
Begutachteter Zeitschriftenartikel
Breast cancer cells in microgravity - new aspects for cancer research
In: International journal of molecular sciences - Basel: Molecular Diversity Preservation International, 2000, Vol. 21.2020, 19, Art.-Nr. 7345, insges. 22 Seiten
Curcumin - a viable agent for better bladder cancer treatment
In: International journal of molecular sciences - Basel: Molecular Diversity Preservation International, 2000, Vol. 21.2020, 11, Art.-Nr. 3761, insgesamt 20 Seiten
Damage-associated molecular patterns in trauma
In: European journal of trauma and emergency surgery: official publication of the European Trauma Society - Heidelberg: Springer Medizin, 2007, Bd. 46.2020, 4, S. 751-775
Different experimental multiple trauma models induce comparable inflammation and organ injury
In: Scientific reports - [London]: Macmillan Publishers Limited, part of Springer Nature, 2011, Vol. 10.2020, Art.-Nr. 20185, insgesamt 12 Seiten
Early local neutralization of CC16 in sepsisinduced ALI following blunt chest trauma leads to delayed mortality without benefitting overall survival
In: International journal of molecular medicine - Athens: Spandidos Publ., 1998, Bd. 46.2020, 6, S. 2207-2215
Effects of circulating HMGB-1 and histones on cardiomyocytes-hemadsorption of these DAMPs as therapeutic strategy after multiple trauma
In: Journal of Clinical Medicine: open access journal - Basel: MDPI, 2012, Bd. 9.2020, 5, Art.-Nr. 1421, insgesamt 13 Seiten
Ethanol intoxication alleviates the inflammatory response of remote organs to experimental traumatic brain injury
In: International journal of molecular sciences - Basel: Molecular Diversity Preservation International, 2000, Vol. 21.2020, 21, Art.-Nr. 8181, insgesamt 14 Seiten
Ethyl pyruvate reduces systemic leukocyte activation via caspase-1 and NF-[kappa]B after blunt chest trauma and haemorrhagic shock
In: Frontiers in medicine - Lausanne: Frontiers Media, 2014, Bd. 7.2020, Art.-Nr. 562904, insgesamt 11 Seiten
Indomethacin increases the efficacy of oxygen utilization of colonic mitochondria and uncouples hepatic mitochondria in tissue homogenates from healthy rats
In: Frontiers in medicine - Lausanne: Frontiers Media, 2014, Bd. 7.2020, Art.-Nr. 463, insgesamt 7 Seiten
Intra-hepatic abscopal effect following radioembolization of hepatic metastases
In: CardioVascular and interventional radiology: CVIR - Berlin: Springer, 1978, Bd. 43.2020, 11, S. 1641-1649
M1 but not M0 extracellular vesicles induce polarization of RAW264.7 macrophages via the TLR4-NF[kappa]B pathway in vitro
In: Inflammation - New York, NY [u.a.]: Springer Science + Business Media B.V., 1975, Bd. 43.2020, 5, S. 1611-1619
Post-traumatic sepsis is associated with increased C5a and decreased TAFI levels
In: Journal of Clinical Medicine: open access journal - Basel: MDPI, 2012, Bd. 9.2020, 4, Art.-Nr. 1230, insgesamt 15 Seiten
Regulatory T cells modulate CD4 proliferation after severe trauma via IL-10
In: Journal of Clinical Medicine: open access journal - Basel: MDPI, 2012, Bd. 9.2020, 4, Art.-Nr. 1052, insgesamt 15 Seiten
SARS-CoV-2/COVID-19 - evolving reality, global response, knowledge gaps, and opportunities
In: Shock: injury, inflammation, and sepsis, laboratory and clinical approaches - Hagerstown, Md.: Lippincott, Williams & Wilkins, Bd. 54.2020, 4, S. 416-437
Short exposure to ethanol diminishes caspase-1 and ASC activation in human HepG2 cells in vitro
In: International journal of molecular sciences - Basel: Molecular Diversity Preservation International, 2000, Vol. 21.2020, 9, Art.-Nr. 3196, insges. 18 Seiten
The impact of acute or chronic alcohol intake on the NF-[kappa]B signaling pathway in alcohol-related liver disease
In: International journal of molecular sciences - Basel: Molecular Diversity Preservation International, 2000, Vol. 21.2020, 24, 9407, insgesamt 35 Seiten
Transarterielle Radioembolisation - Immuneffekte und Immunonkologie
In: Der Radiologe: Zeitschrift für diagnostische und interventionelle Radiologie, Radioonkologie, Nuklearmedizin ; Organ der Arbeitsgemeinschaft Berufsverbände Medizinische Radiologie. Dan - Berlin: Springer, Bd. 60.2020, 8, S. 693-703
Trauma severity and its impact on local inflammation in extremity injury - insights from a combined trauma model in pigs
In: Frontiers in immunology - Lausanne: Frontiers Media, 2010, Vol. 10.2020, Article 3028, insges. 10 Seiten
2019
Begutachteter Zeitschriftenartikel
Club cell protein 16 in sera from trauma patients modulates neutrophil migration and functionality via CXCR1 and CXCR2
In: Molecular medicine: insight into the cellular and molecular basis of disease - [London]: BioMed Central, 1994, Bd.25.2019, Art.-Nr. 45, insges. 13 S.
Curcumin combined with exposure to visible light blocks bladder cancer cell adhesion and migration by an integrin dependent mechanism
In: European review for medical and pharmacological sciences - Roma: Verduci, 1997, Bd. 23.2019, 23, S. 10564-10574
Cytokines in inflammatory disease
In: International journal of molecular sciences - Basel: Molecular Diversity Preservation International, 2000, Bd.20.2019, 23, Art.-Nr. 6008, insges. 31 S.
Endogenous uteroglobin as intrinsic anti-inflammatory signal modulates monocyte and macrophage subsets distribution upon sepsis induced lung injury
In: Frontiers in immunology - Lausanne: Frontiers Media, 2010, Bd.10.2019, Art.-Nr. 2276, insges. 14 S.
Innate immunity and alcohol
In: Journal of Clinical Medicine: open access journal - Basel: MDPI, 2012, Bd.8.2019, 11, Art.-Nr. 1981, insges. 31 S.
Modeling trauma in rats - similarities to humans and potential pitfalls to consider
In: Journal of translational medicine - London: BioMed Central, 2003, Bd. 17.2019, Art.-Nr. 305, insges. 19 S.
2017
Artikel in Zeitschrift
Correction - Renal cell carcinoma alters endothelial receptor expression responsible for leukocyte adhesion
In: OncoTarget: open access impact journal - [S.l.]: Impact Journals LLC, 2010, Bd. 8.2017, 1, S. 1953-1954
2016
Artikel in Zeitschrift
Renal cell carcinoma alters endothelial receptor expression responsible for leukocyte adhesion
In: OncoTarget - [S.l.]: Impact Journals LLC, 2010, Bd. 7.2016, 15, S. 20410-20424
2005
Begutachteter Zeitschriftenartikel
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