Chair of Bioprocess Engineering

Dr. Dirk Benndorf

Institute of Process Engineering
Bioprocess Engineering

Otto von Guericke University Magdeburg
Postfach 4120
D-39016 Magdeburg

Max Planck Institute for Dynamics of Complex Technical Systems
Sandtorstraße 1
Fon: ++49 / 391 / 67-52160
Fax: ++49 / 391 / 67-11209


Bioprocess Engineering:

Coordinator of study course of
Biosystems Engineering

Analysis of natural and artificial mixed cultures

Curriculum Vitae
  • Born in March 1972 in Leipzig.
  • Diploma in biochemistry at University of Leipzig in 1996.
  • From June 1996 to Juli 2007scientist at Helmholtz Centre for Environmental Research - UFZ in the departments of Environmental Microbiology and Proteomics.
  • PhD (biochemistry) in June 2000 (University of Leipzig and Helmholtz Centre for Environmental Research -
    UFZ) Thesis : Molecular Mechanisms of Resistance of Bacteria against Xenobiotics.
  • Since August 2007: scientist at Institute of Process Engineering (Chair of Bioprocess Engineering) in cooperation with Max Planck Institute for Dynamics of Complex Technical Systems.
  • Since July 2017: Adjunct Lecturer, National University of Ireland, Galway, College of Science

Scientific key words

  • Microbiology: Degradation of pollutants, Microbial ecology, Stress Response
  • Proteomics: 2D-PAGE, Mass Spectrometry

Selected publications

  • Koch, S., Benndorf, D., Fronk, K., Reichl, U., Klamt, S. (2016) Predicting compositions of microbial communities from stoichiometric models with applications for the biogas process. Biotechnol Biofuels 9,17. PubMed
  • Heyer, R., Benndorf, D., Kohrs, F., De Vrieze, J., Boon, N., Hoffmann, M., Rapp, E.,Schlüter, A., Sczyrba, A., Reichl, U. (2016) Proteotyping of biogas plant microbiomes separates biogas plants according to process temperature and reactor type. Biotechnol Biofuels  9,155. PubMed
  • Bensmann, A., Hanke-Rauschenbach, R., Heyer, R., Kohrs, F., Benndorf, D., Kausmann, R., Plöchl, M., Heiermann, M., Reichl, U., Sundmacher, K. (2016)  Diagnostic concept for dynamically operated biogas production plants. Renewable Energy 96,479-489
  • Püttker, S., Kohrs, F., Benndorf, D., Heyer, R., Rapp, E., Reichl, U. (2015). Metaproteomics of activated sludge from a wastewater treatment plant - A pilot study. Proteomics 15, 3596-3601. PubMed
  • Kohrs, F., Wolter, S., Benndorf, D., Heyer, R., Hoffmann, M., Rapp, E., Bremges, A., Sczyrba, A., Schlüter, A., Reichl, U. (2015). Fractionation of biogas plant sludge material improves metaproteomic characterization to investigate metabolic activity of microbial communities. Proteomics 15, 3585-3589. PubMed
  • Theuerl, S., Kohrs, F., Benndorf, D., Maus, I., Wibberg, D., Schlüter, A., Kausmann, R., Heiermann, M., Rapp, E., Reichl, U., Pühler, A., Klocke, M. (2015). Community shifts in a well-operating agricultural biogas plant: how process variations are handled by the microbiome. Appl Microbiol Biotechnol., 99, 7791-7803. PubMed
  • Heyer, R., Kohrs, F., Reichl, U., Benndorf, D. (2015). Metaproteomics of complex microbial communities in biogas plants. Microb. Biotechnol., 8, 749–763. PubMed.
  • Muth, T., Behne, A., Heyer, R., Kohrs, F., Benndorf, D., Hoffmann, M., Lehtevä, M., Reichl, U., Martens, L., Rapp, E. (2015). The MetaProteomeAnalyzer: a powerful open-source software suite for metaproteomics data analysis and interpretation. J Proteome Res.14,1557-1565. PubMed
  • Kohrs, F., Heyer, R., Magnussen, A., Benndorf, D., Muth, T., Behne, A., Rapp, E., Kausmann, R., Heiermann, M., Klocke, M., Reichl, U. (2014). Sample prefractionation with liquid isoelectric focusing enables in depth microbial metaproteome analysis of mesophilic and thermophilic biogas plants. Anaerobe 29, 59-67. PubMed
  • Benndorf, D., Reichl, U. (2014). Proteomics in environmental and technical microbiology. Engineering in Life Science 14, 27-46.
  • Heyer, R., Kohrs, F. , Benndorf, D., Rapp, E. , Kausmann, R. ,  Heiermann, M. , Klocke, M., Reichl, U. (2013). Metaproteome analysis of the microbial communities in agricultural biogas plants. New Biotechnology 30, 614-622.PubMed
  • Muth, T., Benndorf, D., Reichl, U., Rapp, E., Martens, L. (2012). Searching for a needle in a stack of needles: challenges in metaproteomics data analysis. Mol. Biosyst. 9, 578-585.PubMed
  • Hanreich, A., Heyer, R., Benndorf, D., Rapp, E.,Pioch, M., Reichl, U., Klocke, M. (2012). Determination of the metabolically active part of a thermophilic microbial community producing biogas from agricultural biomass by metaproteome analysis. Can. J. Microbiol. 58, 917-922.PubMed
  • Kluge, S,Hoffmann, M., Benndorf, D., Rapp, E., Reichl, U. (2012). Proteome Based Tracking and Analysis of a Bacterial Mixed Culture. Proteomics 12, 1893-1901.PubMed
  • Kuhn, R., Benndorf, D., Rapp, E., Reichl, U., Palese, L.L., Pollice, A. (2011). Metaproteome Analysis of Sewage Sludge from Membrane Bioreactors. Proteomics 11, 2738-2744.PubMed
  • Jehmlich, N., Kleinsteuber, S., Vogt, C., Benndorf, D., Harms, H., Schmidt, F., von Bergen, M., Seifert, J. (2010). Phylogenetic and proteomic analysis of an anaerobic toluene-degrading community. J. Appl. Microbiol. 109, 1937-45.PubMed
  • Roma-Rodrigues, C., Santos, P.M., Benndorf, D., Rapp, E., Sá-Correia, I. (2010) Response of Pseudomonas putida KT2440 to phenol at the level of membrane proteome. Journal of Proteomics 73, 1461-1478. PubMed
  • Benndorf, D., Vogt, C., Jehmlich, N., Schmidt, Y,. Thomas, H., Woffendin, G., Shevchenko, A., Richnow, H.H., von Bergen, M. (2009) Improving protein extraction and separation methods for investigating the metaproteome of anaerobic benzene communities within sediments. Biodegradation 20, 737-750. PubMed
  • Benndorf, D ., Balcke, G.U., Harms, H. and von Bergen, M. (2007). Functional metaproteome analysis of protein extracts from contaminated soil and groundwater. The ISME Journal 1 , 224-234.
  • Wiacek, C., Müller, S. and Benndorf, D. (2006). Population heterogeneity of Cupriavidus necator using flow cytometry and proteome analysis. Proteomics 6 , 5983-5994. PubMed
  • Santos , P. M., Benndorf, D. and Sá-Correia, I. (2004). A proteomic analysis of the responses to phenol-induced stress in Pseudomonas putida KT2440. Proteomics 4 , 2640-2652. PubMed